Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

ERCC6L CHD3 CHD4 SRCAP

1.50e-0537814GO:0140658
GeneOntologyMolecularFunctionATP-dependent activity

MDN1 MYL6 ERCC6L MYO18A ACIN1 CHD3 CHD4 SRCAP MYO15A ATP2B4 ABCA8

3.66e-056148111GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

MDN1 ERCC6L MYO18A ACIN1 CHD3 CHD4 SRCAP ATP2B4 ABCA8

7.36e-05441819GO:0016887
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

9.70e-054812GO:0005219
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

ERCC6L MYO18A CHD3 CHD4 SRCAP

1.67e-04127815GO:0008094
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.41e-046812GO:0048763
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM6 STIM2 ATP2B4 RYR2 RYR3

3.73e-04151815GO:0015085
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2D SETD7

4.48e-048812GO:0140945
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor 2 binding

PDCL3 CDH5

7.16e-0410812GO:0043184
GeneOntologyMolecularFunctionprotein phosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

1.10e-0350813GO:0004864
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BAZ1A SRCAP KAT6B

1.16e-0351813GO:0004402
GeneOntologyMolecularFunctionphosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

1.37e-0354813GO:0019212
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BAZ1A SRCAP KAT6B

1.45e-0355813GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BAZ1A SRCAP KAT6B

1.86e-0360813GO:0034212
GeneOntologyMolecularFunctioncalcium channel activity

TRPM6 STIM2 RYR2 RYR3

1.88e-03129814GO:0005262
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor binding

PDCL3 CDH5

2.12e-0317812GO:0005172
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR2 RYR3

2.38e-0318812GO:0015278
GeneOntologyMolecularFunctionhistone modifying activity

KMT2D BAZ1A SETD7 SRCAP KAT6B

2.40e-03229815GO:0140993
GeneOntologyMolecularFunctioncalmodulin binding

CALD1 MYO15A ATP2B4 RYR2 RYR3

2.44e-03230815GO:0005516
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM6 STIM2 KCNK9 ATP2B4 RYR2 RYR3 TFRC

2.80e-03465817GO:0046873
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2D SETD7

2.94e-0320812GO:0042800
GeneOntologyMolecularFunctionhelicase activity

ERCC6L CHD3 CHD4 SRCAP

3.91e-03158814GO:0004386
GeneOntologyMolecularFunctionN-acetyltransferase activity

BAZ1A SRCAP KAT6B

3.93e-0378813GO:0008080
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MDN1 ERCC6L MYO18A ACIN1 CHD3 CHD4 SRCAP ATP2B4 ABCA8

4.10e-03775819GO:0017111
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERCC6L MYO18A CHD3 CHD4 SRCAP

4.26e-03262815GO:0140097
GeneOntologyMolecularFunctionhistone binding

SPIN1 MLLT3 CHD3 CHD4 SRCAP

4.47e-03265815GO:0042393
GeneOntologyBiologicalProcessprotein-DNA complex organization

BDP1 KMT2D CENPT ERCC6L UBR5 BAZ1A RRN3 SPIN1 MLLT3 CHD3 CHD4 SETD7 SRCAP KAT6B

2.01e-059997814GO:0071824
DomainZF_PHD_2

KMT2D JADE3 BAZ1A ASXL3 CHD3 CHD4 KAT6B

1.65e-0795807PS50016
DomainZF_PHD_1

KMT2D JADE3 BAZ1A ASXL3 CHD3 CHD4 KAT6B

1.78e-0796807PS01359
DomainPHD

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

8.12e-0775806PF00628
DomainZnf_PHD-finger

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

1.11e-0679806IPR019787
DomainPHD

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

2.24e-0689806SM00249
DomainZnf_PHD

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

2.55e-0691806IPR001965
DomainSNF2_N

ERCC6L CHD3 CHD4 SRCAP

1.02e-0532804IPR000330
DomainSNF2_N

ERCC6L CHD3 CHD4 SRCAP

1.02e-0532804PF00176
DomainEF-hand-dom_pair

STIM2 MYL6 DTNB TNNC2 UTRN RYR2 RYR3 CAPN11

3.14e-05287808IPR011992
DomainZnf_FYVE_PHD

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

3.99e-05147806IPR011011
DomainCHDCT2

CHD3 CHD4

5.42e-053802PF08074
DomainCHDNT

CHD3 CHD4

5.42e-053802PF08073
DomainRyanrecept_TM4-6

RYR2 RYR3

5.42e-053802IPR009460
DomainDUF1086

CHD3 CHD4

5.42e-053802IPR009462
DomainDUF1087

CHD3 CHD4

5.42e-053802IPR009463
DomainCHD_N

CHD3 CHD4

5.42e-053802IPR012958
DomainCHD_C2

CHD3 CHD4

5.42e-053802IPR012957
DomainRyR

RYR2 RYR3

5.42e-053802PF02026
DomainRyanodine_rcpt

RYR2 RYR3

5.42e-053802IPR003032
DomainRR_TM4-6

RYR2 RYR3

5.42e-053802PF06459
DomainDUF1087

CHD3 CHD4

5.42e-053802PF06465
DomainDUF1086

CHD3 CHD4

5.42e-053802PF06461
DomainDUF1087

CHD3 CHD4

5.42e-053802SM01147
DomainDUF1086

CHD3 CHD4

5.42e-053802SM01146
DomainRyan_recept

RYR2 RYR3

5.42e-053802IPR013333
Domain-

MYL6 DTNB TNNC2 UTRN RYR2 RYR3 CAPN11

1.28e-042618071.10.238.10
DomainZinc_finger_PHD-type_CS

JADE3 BAZ1A CHD3 CHD4

1.73e-0465804IPR019786
DomainAlpha_kinase

TRPM6 ALPK2

2.69e-046802PF02816
DomainRIH_assoc

RYR2 RYR3

2.69e-046802PF08454
DomainRIH_assoc-dom

RYR2 RYR3

2.69e-046802IPR013662
DomainRIH_dom

RYR2 RYR3

2.69e-046802IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

2.69e-046802IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

2.69e-046802IPR015925
DomainALPHA_KINASE

TRPM6 ALPK2

2.69e-046802PS51158
DomainAlpha_kinase

TRPM6 ALPK2

2.69e-046802SM00811
Domain-

RYR2 RYR3

2.69e-0468021.25.10.30
DomainMHCK_EF2_kinase

TRPM6 ALPK2

2.69e-046802IPR004166
DomainEF-hand_dom_typ1

DTNB UTRN

2.69e-046802IPR015153
DomainEF-hand_dom_typ2

DTNB UTRN

2.69e-046802IPR015154
DomainRYDR_ITPR

RYR2 RYR3

2.69e-046802PF01365
DomainEF-hand_2

DTNB UTRN

2.69e-046802PF09068
DomainEF-hand_3

DTNB UTRN

2.69e-046802PF09069
DomainIns145_P3_rec

RYR2 RYR3

2.69e-046802PF08709
DomainEF-hand_8

TNNC2 RYR2 CAPN11

4.11e-0434803PF13833
DomainEF_HAND_2

STIM2 MYL6 TNNC2 RYR2 RYR3 CAPN11

4.70e-04231806PS50222
DomainEF-hand_1

MYL6 TNNC2 RYR2 RYR3 CAPN11

4.92e-04152805PF00036
DomainMIR

RYR2 RYR3

7.97e-0410802PS50919
DomainMIR

RYR2 RYR3

7.97e-0410802PF02815
DomainMIR

RYR2 RYR3

7.97e-0410802SM00472
DomainMIR_motif

RYR2 RYR3

7.97e-0410802IPR016093
DomainHelicase_C

ERCC6L CHD3 CHD4 SRCAP

1.15e-03107804PF00271
DomainHELICc

ERCC6L CHD3 CHD4 SRCAP

1.15e-03107804SM00490
DomainHelicase_C

ERCC6L CHD3 CHD4 SRCAP

1.19e-03108804IPR001650
DomainHELICASE_CTER

ERCC6L CHD3 CHD4 SRCAP

1.23e-03109804PS51194
DomainHELICASE_ATP_BIND_1

ERCC6L CHD3 CHD4 SRCAP

1.23e-03109804PS51192
DomainDEXDc

ERCC6L CHD3 CHD4 SRCAP

1.23e-03109804SM00487
DomainHelicase_ATP-bd

ERCC6L CHD3 CHD4 SRCAP

1.28e-03110804IPR014001
DomainZZ

DTNB UTRN

2.65e-0318802PF00569
DomainZF_ZZ_2

DTNB UTRN

2.65e-0318802PS50135
DomainZF_ZZ_1

DTNB UTRN

2.65e-0318802PS01357
DomainHMG_box_dom

KMT2D CHD3 CHD4

2.73e-0365803IPR009071
DomainZnf_ZZ

DTNB UTRN

2.96e-0319802IPR000433
DomainZnF_ZZ

DTNB UTRN

2.96e-0319802SM00291
DomainEF_hand_dom

MYL6 TNNC2 RYR2 RYR3 CAPN11

3.20e-03232805IPR002048
DomainIQ

MYO18A MYO15A IQCD

3.51e-0371803PF00612
DomainEPHD

KMT2D JADE3

3.96e-0322802PS51805
PathwayREACTOME_MUSCLE_CONTRACTION

MYL6 CALD1 TNNC2 KCNK9 ATP2B4 RYR2 RYR3

4.28e-06165577MM15026
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOR2 KMT2D JADE3 CHD3 CHD4 SETD7 KAT6B

6.31e-06175577MM14941
PathwayREACTOME_MUSCLE_CONTRACTION

MYL6 CALD1 TNNC2 KCNK9 ATP2B4 RYR2 RYR3

1.66e-05203577M5485
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOR2 KMT2D JADE3 CHD3 CHD4 SETD7 KAT6B

1.07e-04272577M29619
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

THOC1 NUP155 SRSF11 RBM8A

3.64e-0484574M725
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

THOC1 NUP155 SRSF11 RBM8A

3.99e-0486574MM15413
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

THOC1 BDP1 NCOR2 KMT2D NUP155 ZKSCAN1 RRN3 MLLT3 SRSF11 RBM8A CHD3 CHD4

6.63e-0410225712MM15436
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK9 ATP2B4 RYR2 RYR3

7.89e-04103574MM15196
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR2 RYR3

8.63e-0411572M47958
PathwayREACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION

RRN3 CHD3 CHD4

8.96e-0447573M1095
PathwayREACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

RRN3 CHD3 CHD4

8.96e-0447573MM15428
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

THOC1 PPP1R2 PASK NCOR2 KMT2D PAXBP1 MDN1 RAPH1 ERCC6L JADE3 MYO18A ACIN1 TAOK1 RBM8A CHD3 CHD4 PATL1 KAT6B

2.28e-13774821815302935
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

THOC1 IPO5 EMC3 MDN1 NUP155 CALD1 UBR5 BAZ1A ACIN1 SRSF11 RBM8A CHD3 CHD4 SRCAP UTRN TFRC

1.92e-091024821624711643
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MAP9 STIM2 MDN1 CALD1 RAPH1 BAZ1A DTNB MYO18A DNAJC21 ACIN1 SRSF11 CHD3 CHD4 PTPN21 SRCAP RYR2 CAPN11 TFRC

5.54e-091442821835575683
Pubmed

Structural basis for regulation of protein phosphatase 1 by inhibitor-2.

PPP1R2 PPP1R2B PPP1R2P1

1.26e-08382317636256
Pubmed

Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.

PPP1R2 PPP1R2B PPP1R2P1

5.04e-0848237949733
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

THOC1 NCOR2 KMT2D PAXBP1 MDN1 MYL6 JADE3 BAZ1A UBP1 ACIN1 SRSF11 RBM8A CHD3 CHD4 MLXIP SRCAP

5.08e-081294821630804502
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

THOC1 IPO5 NCOR2 MDN1 NUP155 UBR5 BAZ1A NANS ACIN1 RBM8A CHD3 CHD4 MYO15A TFRC

1.02e-071014821432416067
Pubmed

Regulators of the protein phosphatase PP1γ2, PPP1R2, PPP1R7, and PPP1R11 are involved in epididymal sperm maturation.

PPP1R2 PPP1R2B PPP1R2P1

1.26e-07582330144392
Pubmed

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.

PPP1R2 PPP1R2B PPP1R2P1

1.26e-07582326558779
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

THOC1 PPP1R2 IPO5 NCOR2 CCDC9B PAXBP1 MYL6 DNAJC21 ACIN1 MLLT3 SRSF11 RBM8A CHD4 PATL1 NFU1

2.01e-071247821527684187
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

PAXBP1 MYL6 CALD1 RAPH1 PDCL3 ACIN1 SRSF11 CHD4 SRCAP UTRN

3.26e-07506821030890647
Pubmed

The functional interactome landscape of the human histone deacetylase family.

IPO5 NCOR2 PAXBP1 MDN1 UBR5 ACIN1 CHD3 CHD4

4.32e-0728982823752268
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

THOC1 MYL6 NUP155 CALD1 BAZ1A UBP1 MYO18A ACIN1 SRSF11 RBM8A TFRC

4.37e-07660821132780723
Pubmed

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

PPP1R2 PPP1R2B PPP1R2P1

4.39e-07782318689497
Pubmed

Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.

PPP1R2 PPP1R2B PPP1R2P1

7.01e-07882336693320
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PPP1R2 PIK3AP1 MYL6 CALD1 RAPH1 UBR5 JADE3 NANS PDCL3 PATL1 MLXIP MAST2

7.54e-07853821228718761
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP1R2 RALGAPA1 NCOR2 KMT2D EMC3 NUP155 RAPH1 DTNB SETD7 PEAK1 PTPN21 UTRN ATP2B4

1.03e-061049821327880917
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

IPO5 NCOR2 MDN1 NUP155 ERCC6L ACIN1 TAOK1 SRSF11 CHD3 CHD4

1.16e-06582821020467437
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

PPP1R2 NCOR2 PPP1R2B STIM2 MYL6 CALD1 JADE3 DTNB RBM8A CHD4 UTRN NFU1

1.48e-06910821236736316
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TRPM6 MAP9 PAXBP1 BAZ1A UBP1 SPIN1 ACIN1 TAOK1 CHD3 PATL1 PEAK1 SRCAP UTRN

1.48e-061084821311544199
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

KMT2D MLLT3 CHD3 CHD4 SRCAP KAT6B

2.03e-0615782630186101
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

THOC1 NCOR2 CENPT PAXBP1 MYL6 CALD1 BAZ1A ACIN1 SRSF11 RBM8A CHD3 CHD4

2.41e-06954821236373674
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

IPO5 MDN1 MYL6 NANS RBM8A CHD4 PEAK1 SRCAP MYO15A UTRN TFRC

3.07e-06807821130575818
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

THOC1 PAXBP1 MYL6 BAZ1A SPIN1 ACIN1 COL14A1 TAOK1 SRSF11 RBM8A CHD3 CHD4 PATL1 ATP2B4

3.67e-061371821436244648
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

PAXBP1 MDN1 MYL6 BAZ1A UBP1 ACIN1 SRSF11 RBM8A CHD3 CHD4 TFRC

4.86e-06847821135850772
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

PPP1R2 RALGAPA1 BDP1 KMT2D MLLT3

5.41e-0610682531024071
Pubmed

Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.

PIK3AP1 CFAP36 DNAJC21 NCKAP5 NFU1

5.41e-0610682518654987
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

5.49e-0628227560064
Pubmed

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.

PPP1R2 PPP1R2B

5.49e-06282223506001
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

5.49e-06282221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

5.49e-06282216678258
Pubmed

The metabolic sensor PASK is a histone 3 kinase that also regulates H3K4 methylation by associating with H3K4 MLL2 methyltransferase complex.

PASK KMT2D

5.49e-06282231529049
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

5.49e-0628227575689
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

5.49e-0628228898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

5.49e-06282214550562
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

5.49e-06282214985349
Pubmed

Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development.

CHD3 CHD4

5.49e-06282235568926
Pubmed

Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen.

CHD3 CHD4

5.49e-0628228843877
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 STIM2 MDN1 RAPH1 ERCC6L SRSF11 PEAK1 PTPN21 MLXIP MAST2 UTRN

5.68e-06861821136931259
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

NCOR2 DNAJC21 ACIN1 SRSF11 RYR2 RYR3

6.28e-0619182620195357
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

RALGAPA1 PAXBP1 CALD1 SRSF11 UTRN RYR2

7.49e-0619782620811636
Pubmed

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.

IPO5 PDCD2 MYL6 ERCC6L CFAP36 CALCOCO1

8.40e-0620182634917906
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RALGAPA1 PASK STIM2 EMC3 PAXBP1 MDN1 NUP155 UBR5 MYO18A DNAJC21 COL14A1 PEAK1 ATP2B4 TFRC

9.25e-061487821433957083
Pubmed

Functional proteomics mapping of a human signaling pathway.

NCOR2 STIM2 KMT2D NUP155 UBR5 BAZ1A CHD3 UTRN RYR2

1.08e-0559182915231748
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

UBR5 MYO18A ACIN1 RBM8A

1.18e-055982416083285
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PPP1R2B MYL6 CALD1 RAPH1 ERCC6L BAZ1A ACIN1 CHD3 CHD4 SRCAP UTRN

1.22e-05934821133916271
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

IPO5 KMT2D PAXBP1 MYL6 BAZ1A ACIN1 CHD3 IQCD

1.53e-0546982827634302
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NCOR2 PDCD2 MDN1 NUP155 UBR5 BAZ1A NANS ACIN1 RBM8A CHD4 SRCAP UTRN TFRC

1.62e-051353821329467282
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

1.64e-05382218403125
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

1.64e-05382218434746
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

1.64e-05382229730765
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

1.64e-0538229204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

1.64e-0538227876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

1.64e-05382221881589
Pubmed

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.

PPP1R2 PPP1R2B

1.64e-05382224195737
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

1.64e-05382212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

1.64e-0538229242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

1.64e-05382222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

1.64e-05382210788707
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

1.64e-05382215024040
Pubmed

The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.

CHD3 CHD4

1.64e-05382232658897
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

1.64e-05382225239916
Pubmed

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.

KMT2D CHD3

1.64e-05382226551667
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

1.64e-0538227621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

1.64e-05382218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

1.64e-05382211159936
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

1.64e-05382210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

1.64e-0538227959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

1.64e-0538224600883
Pubmed

Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs.

ERCC6L TAOK1

1.64e-05382219904549
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

1.64e-0538227635066
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

THOC1 KMT2D CHD4 SRCAP

2.21e-056982428481362
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

RAPH1 BAZ1A ASXL3 PDCL3 CALCOCO1 SRSF11 MAST2

2.39e-0536182726167880
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

IPO5 MDN1 TAOK1 NCKAP5 SRCAP MAST2 UTRN

2.47e-0536382714691545
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

UBR5 DTNB USP4 CHD4 UTRN

2.65e-0514782529576527
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

THOC1 TRPM6 IPO5 PAXBP1 MDN1 MYL6 NUP155 BAZ1A ACIN1 CHD4 PEAK1 MAST2 TFRC

2.79e-051425821330948266
Pubmed

Characterization of the CHD family of proteins.

CHD3 CHD4

3.28e-0548229326634
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

3.28e-05482218206662
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

3.28e-05482223413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

3.28e-0548229384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

3.28e-0548229607712
Pubmed

NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.

CHD3 CHD4

3.28e-05482216574654
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

3.28e-05482223482488
Pubmed

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.

DTNB UTRN RYR2

3.55e-052782318468998
Pubmed

Luzp4 defines a new mRNA export pathway in cancer cells.

THOC1 CALD1 ACIN1 RBM8A

3.96e-058082425662211
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

RALGAPA1 NCOR2 MDN1 MYL6 UBR5 CHD3 KAT6B UTRN

4.07e-0553882828524877
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RALGAPA1 PKNOX2 BDP1 NCOR2 CALD1 DTNB SPIN1 CALCOCO1 SRSF11 CHD3 PATL1 KAT6B UTRN

4.38e-051489821328611215
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

KMT2D TRANK1 MYL6 ASXL3 TAOK1 MLXIP UTRN ATP2B4

4.87e-0555282810737800
Pubmed

Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.

KMT2D MYL6 ACIN1 RBM8A CHD4

5.30e-0517082516159877
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

THOC1 IPO5 KMT2D PAXBP1 ACIN1 CHD3 UTRN

5.34e-0541082726949251
Pubmed

Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.

PPP1R2 PPP1R2B PPP1R2P1

5.41e-053182315778864
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

5.47e-05582233060591
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

5.47e-05582223918386
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

5.47e-05582219011160
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

KLHL38 RALGAPA1 STIM2 ERCC6L DTNB PEAK1 ATP2B4 TFRC

6.02e-0556982830639242
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR2 KMT2D RAPH1 UBR5 CHD3 CHD4 UTRN

6.03e-0541882734709266
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PASK NCOR2 MYL6 UBR5 CFAP36 CHD3 CHD4 SRCAP KAT6B MAST2 ABCA8

6.17e-051116821131753913
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

THOC1 MDN1 NUP155 BAZ1A MYO18A DNAJC21 ACIN1 CHD3 CHD4

7.58e-0575982935915203
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR2 RYR3

8.19e-05682219549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR2 RYR3

8.19e-05682226025922
InteractionNUP43 interactions

NCOR2 KMT2D CENPT PAXBP1 UBR5 JADE3 BAZ1A PDCL3 ACIN1 CHD3 SRCAP RYR2

7.14e-066258112int:NUP43
InteractionSRRM1 interactions

KMT2D CALD1 UBR5 ACIN1 USP4 SRSF11 RBM8A CHD3 CHD4

1.08e-05348819int:SRRM1
InteractionZNF622 interactions

PPP1R2 UBR5 DNAJC21 RBM8A CHD3 CHD4

1.23e-05127816int:ZNF622
InteractionSF3A1 interactions

THOC1 PAXBP1 ASXL3 ACIN1 USP4 RBM8A CHD3 CHD4 PATL1 SRCAP

1.88e-054718110int:SF3A1
InteractionYWHAG interactions

RALGAPA1 LNP1 STIM2 MDN1 RAPH1 ERCC6L BAZ1A ACIN1 TAOK1 SRSF11 PEAK1 PTPN21 MLXIP MAST2 KCNK9 UTRN

3.12e-0512488116int:YWHAG
InteractionKDR interactions

MDN1 NUP155 BAZ1A PDCL3 ACIN1 CDH5

3.15e-05150816int:KDR
InteractionCALM1 interactions

STIM2 MYL6 CALD1 ZKSCAN1 UBR5 MYO18A RBM8A PEAK1 UTRN ATP2B4 RYR2

4.01e-056268111int:CALM1
InteractionPRP4K interactions

THOC1 PAXBP1 UBR5 BAZ1A ACIN1 SRSF11 RBM8A CHD4

5.29e-05329818int:PRP4K
InteractionOBSL1 interactions

THOC1 PASK MDN1 NUP155 CALD1 ACIN1 SRSF11 RBM8A CHD4 PTPN21 SRCAP UTRN ALPK2

5.92e-059028113int:OBSL1
InteractionSARNP interactions

THOC1 UBR5 ACIN1 CHD3 SRCAP ABCA8

5.94e-05168816int:SARNP
InteractionTWIST1 interactions

MYL6 NUP155 UBR5 USP4 CHD3 CHD4

6.34e-05170816int:TWIST1
InteractionAGR2 interactions

THOC1 KLHL38 IPO5 MDN1 MYL6 NANS RBM8A CHD4 PEAK1 SRCAP MYO15A UTRN TFRC

8.43e-059348113int:AGR2
InteractionNUPR1 interactions

THOC1 MYL6 NUP155 CALD1 BAZ1A UBP1 MYO18A ACIN1 SRSF11 RBM8A TFRC

8.77e-056838111int:NUPR1
InteractionTHOC7 interactions

THOC1 PPP1R2 CCDC9B RBM8A CHD3

9.65e-05114815int:THOC7
InteractionACTC1 interactions

PAXBP1 MYL6 CALD1 RAPH1 PDCL3 ACIN1 SRSF11 CHD3 CHD4 SRCAP UTRN

1.01e-046948111int:ACTC1
InteractionGSK3A interactions

PPP1R2 PASK PPP1R2B MDN1 UBR5 ACIN1 RBM8A PEAK1 UTRN

1.01e-04464819int:GSK3A
InteractionSUMO2 interactions

IPO5 MDN1 BAZ1A ACIN1 RBM8A CHD3 CHD4 SRCAP MAST2 ABCA8

1.26e-045918110int:SUMO2
InteractionPAXBP1 interactions

THOC1 PAXBP1 UBR5 CHD3 CHD4

1.28e-04121815int:PAXBP1
InteractionRNF2 interactions

THOC1 KMT2D CCDC9B UBR5 OTUD6A DNAJC21 ACIN1 MLLT3 RBM8A CHD3 CHD4 TFRC

1.69e-048668112int:RNF2
InteractionPPP1CC interactions

PPP1R2 PPP1R2B MYL6 CALD1 RAPH1 UBR5 ACIN1 CHD3 CHD4 PEAK1 RYR2

1.73e-047388111int:PPP1CC
InteractionCEBPB interactions

THOC1 IPO5 PIK3AP1 NCOR2 KMT2D MYL6 BAZ1A NANS UBP1 SPIN1 ACIN1 MLLT3 SRSF11 RBM8A CHD4 TFRC

1.73e-0414438116int:CEBPB
InteractionZBTB7A interactions

NCOR2 MDN1 UBR5 CHD3 CHD4

1.85e-04131815int:ZBTB7A
InteractionTHOC1 interactions

THOC1 CCDC9B PAXBP1 RBM8A CHD4 UTRN

2.02e-04210816int:THOC1
InteractionACIN1 interactions

UBR5 ACIN1 USP4 SRSF11 RBM8A CHD3 CHD4

2.09e-04301817int:ACIN1
InteractionPLAC9 interactions

EMC3 MYO18A ATP2B4

2.12e-0429813int:PLAC9
InteractionMEN1 interactions

THOC1 KMT2D PAXBP1 MDN1 UBR5 BAZ1A ACIN1 RBM8A CHD3 CHD4 SRCAP KAT6B TFRC

2.20e-0410298113int:MEN1
InteractionSAP18 interactions

CALD1 UBR5 ACIN1 SRSF11 RBM8A CHD3 CHD4

2.27e-04305817int:SAP18
InteractionSUPT5H interactions

THOC1 NCOR2 KMT2D UBR5 ACIN1 RBM8A CHD3 CHD4

2.33e-04408818int:SUPT5H
GeneFamilyPHD finger proteins

KMT2D JADE3 BAZ1A CHD3 CHD4 KAT6B

3.42e-079056688
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

2.82e-053562287
GeneFamilyEF-hand domain containing

MYL6 TNNC2 RYR2 RYR3 CAPN11

5.76e-04219565863
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD4

6.10e-04125621305
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DTNB UTRN

1.40e-031856291
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOR2 KMT2D

2.70e-0325562775
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2D SETD7

4.96e-0334562487
CoexpressionKARLSSON_TGFB1_TARGETS_UP

PPP1R2 IPO5 PPP1R2B BAZ1A PPP1R2P1 CHD3

2.98e-06127826MM1289
CoexpressionGSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_DN

THOC1 PIK3AP1 JADE3 NANS DNAJC21 CD79B RBM8A

3.18e-06200827M6989
CoexpressionVANASSE_BCL2_TARGETS_UP

PPP1R2 PPP1R2B PPP1R2P1 RYR2

1.00e-0543824MM799
CoexpressionLEE_AGING_MUSCLE_DN

PPP1R2 PPP1R2B PPP1R2P1 USP4

1.31e-0546824MM670
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

IPO5 PASK UBR5 BAZ1A NANS SPIN1 USP4 MAST2

1.98e-05367828M41159
CoexpressionGABRIELY_MIR21_TARGETS

CALD1 RAPH1 UBR5 SPIN1 SRSF11 UTRN ATP2B4

3.46e-05289827M2196
CoexpressionMURARO_PANCREAS_BETA_CELL

PPP1R2 NCOR2 RAPH1 RRN3 CFAP36 SPIN1 TAOK1 PATL1 VAT1L SETD7 KAT6B UTRN

3.69e-059468212M39169
CoexpressionGSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN

THOC1 PIK3AP1 JADE3 SPIN1 CD79B MAST2

3.96e-05200826M8096
CoexpressionGSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN

CENPT ERCC6L BAZ1A PDCL3 CD79B NFU1

3.96e-05200826M6601
CoexpressionOCONNOR_PBMC_MENVEO_ACWYVAX_AGE_30_70YO_7DY_AFTER_SECOND_DOSE_VS_7DY_AFTER_FIRST_DOSE_UP

MYL6 ACIN1 CHD4 KAT6B ATP2B4

9.68e-05146825M41190
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

IPO5 RALGAPA1 PDCD2 MDN1 UBR5 BAZ1A RRN3 PDCL3 ANKRD10 USP4 RBM8A NFU1 RYR3

9.71e-0512158213M41122
CoexpressionGSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_UP

COL14A1 CD79B PATL1 MYO15A KCNK9

1.06e-04149825M2908
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

CALD1 NCKAP5 MAST2 ATP2B4 ALPK2 RYR2

1.31e-0619081693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

MYL6 CALD1 ZKSCAN1 BAZ1A MLLT3 SETD7

1.57e-0619681638da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

MYL6 CALD1 ZKSCAN1 BAZ1A MLLT3 SETD7

1.57e-06196816721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellTCGA-Lung-Solid_Tissue_Normal|TCGA-Lung / Sample_Type by Project: Shred V9

PKNOX2 NCKAP5 PTPN21 CDH5 ABCA8

1.31e-05166815a8ebdd3cb7f59b3feeaacda45ce6d40d10db556f
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung|TCGA-Lung / Sample_Type by Project: Shred V9

PKNOX2 NCKAP5 PTPN21 CDH5 ABCA8

1.31e-05166815c64971c27cb445dffc5a636d4b6a60261b93a2db
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue|TCGA-Lung / Sample_Type by Project: Shred V9

PKNOX2 NCKAP5 PTPN21 CDH5 ABCA8

1.31e-051668152f3072a7af048f184d33065fdd36153fd563155a
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue-6|TCGA-Lung / Sample_Type by Project: Shred V9

PKNOX2 NCKAP5 PTPN21 CDH5 ABCA8

1.31e-05166815188f2575511f418216874aed9118aa6f165252cb
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

TRPM6 JADE3 ASXL3 CHD3 ALPK2

1.52e-05171815ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PKNOX2 CALD1 MLLT3 NCKAP5 RYR2

1.84e-05178815185b44700f06ec58b3c09c80520502166c965fd6
ToppCellAT1_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC9B NCKAP5 PEAK1 PTPN21 ABCA8

1.94e-05180815e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 ASXL3 MYO15A RYR2 RYR3

2.16e-051848152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKNOX2 CALD1 RAPH1 COL14A1 ABCA8

2.16e-05184815c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 ASXL3 MYO15A RYR2 RYR3

2.16e-05184815ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 ASXL3 MYO15A RYR2 RYR3

2.16e-051848152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NCKAP5 MAST2 ATP2B4 ALPK2 RYR2

2.45e-051898150a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

LRRC46 MAP9 JADE3 CFAP36 MAST2

2.58e-0519181537cf121e6e80760c8519075b7845b9029958a988
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL6 CALD1 COL14A1 TNNC2 ATP2B4

2.71e-0519381588916d9a7d831eb52848599917c04238f8f9812b
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PASK MYL6 TAOK1 PATL1 TFRC

2.78e-051948156cf9d59aec8dd18fa2fc1652ddd0f5ef1f24bcb6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKNOX2 TRANK1 CALD1 RAPH1 ABCA8

2.78e-0519481581713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKNOX2 TRANK1 CALD1 RAPH1 ABCA8

2.78e-05194815627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Central_Memory_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PASK MYL6 NANS PDCL3 RBM8A

2.85e-051958150a200e43e861d5a24c07244c576bba5d67efcf2d
ToppCellASK452|World / Donor, Lineage and Cell class of Lung cells from Dropseq

CALD1 BAZ1A COL14A1 TAOK1 RYR2

2.85e-051958157efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCKAP5 PEAK1 PTPN21 UTRN ABCA8

2.92e-051968156731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCOR2 CALD1 ANKRD10 CDH5 RYR3

2.92e-05196815b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

2.92e-05196815bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCKAP5 PEAK1 PTPN21 UTRN ABCA8

2.92e-051968156856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IPO5 PKNOX2 PDCD2 NANS PDCL3

2.99e-05197815ec92d60f802c9d4bdf9877bed5c0a91a5a5ed5d0
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

2.99e-05197815fb847f2277609c31fffcdf49517243ce0684facf
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IPO5 PKNOX2 PDCD2 NANS PDCL3

2.99e-051978157bec9c1bc8851064eb229324493b47a31201c83c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

PKNOX2 COL14A1 ABCA8 RYR2 RYR3

3.07e-051988150c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.07e-05198815df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MAP9 STIM2 EMC3 BAZ1A UTRN

3.07e-0519881576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.07e-0519881521cf4d81386761d09d0f6829c01c198e5524176d
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.14e-051998154bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.22e-05200815389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 PAXBP1 ACIN1 SRSF11 UTRN

3.22e-0520081512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.22e-05200815cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.22e-05200815cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

TRANK1 PEAK1 SRCAP UTRN ATP2B4

3.22e-052008152281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKNOX2 CALD1 COL14A1 ABCA8 RYR2

3.22e-05200815311fab076f2ceb258e3970eb21e39344b894042a
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CCDC9B CALD1 RYR2 RYR3

1.75e-04153814ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO18A NCKAP5 PEAK1

1.79e-046081328415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO18A NCKAP5 PEAK1

1.79e-046081371eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ASXL3 MLLT3 NCKAP5 VAT1L

2.02e-04159814a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

CALD1 COL14A1 RYR2 RYR3

2.12e-0416181464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PPP1R2 MYO18A CHD3 ABCA8

2.22e-0416381443887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CCDC9B CENPT DTNB ARMC9

2.28e-04164814d6806deabf5f5c355934387be2baae125ac33fb8
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NCKAP5 PEAK1 PTPN21 ABCA8

2.55e-04169814815474855a70498a74e52f6583113c63b7267a0c
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

PKNOX2 CALD1 COL14A1 ABCA8

2.55e-0416981447fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PKNOX2 CALD1 COL14A1 ABCA8

2.55e-04169814e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKNOX2 CALD1 COL14A1 ABCA8

2.55e-04169814a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 KAT6B UTRN TFRC

2.67e-041718142e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 RAPH1 COL14A1 ABCA8

2.73e-041728141ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 RAPH1 COL14A1 ABCA8

2.73e-04172814ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NCKAP5 PEAK1 UTRN ABCA8

2.79e-041738143afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CALD1 COL14A1 RYR2 RYR3

2.79e-04173814a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKNOX2 CALD1 COL14A1 RYR2

2.85e-04174814015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 RAPH1 VAT1L PEAK1

2.91e-041758141b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

KMT2D RRN3 SETD7 UTRN

2.98e-041768142049767fd591045cfcf5b1071d80798e52843f27
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PASK PDCD2 UBP1 ABCA8

2.98e-04176814e08e7a6dd0208acfbb8646d71915af822a64b5de
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PASK PDCD2 UBP1 ABCA8

2.98e-04176814b8264cdda75c5145d8bf8ae00b3e05393fe9a92b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PASK PDCD2 UBP1 ABCA8

2.98e-041768144aee9fdada077db7e531684ab938153f84dc8146
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CALD1 COL14A1 ABCA8 RYR2

3.04e-04177814cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

CALD1 COL14A1 ABCA8 RYR2

3.04e-04177814db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 PEAK1 UTRN CDH5

3.11e-04178814ad3de3e03a401dac64431a541899445262246347
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

PDCL3 COL14A1 CHD3 TNNC2

3.17e-041798145f7e6670a0e906a0a5bc75735408361d88e78fa2
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

NCKAP5 TNNC2 PTPN21 ABCA8

3.24e-041808142d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 RAPH1 VAT1L PEAK1

3.31e-04181814a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

STIM2 PAXBP1 UTRN ATP2B4

3.31e-04181814986c036e656f24fe374807e2711cec9e3c83c892
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 PEAK1 UTRN CDH5

3.31e-04181814e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 RAPH1 VAT1L PEAK1

3.31e-04181814526e858a848470b6d2d5248788004d9735ed3add
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PKNOX2 CALD1 ABCA8 RYR2

3.31e-041818149ede19228ba5c0668a9c06c915510b95585216ef
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYL6 CALD1 ARMC9 ATP2B4

3.31e-04181814beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

NCKAP5 ATP2B4 ALPK2 RYR2

3.38e-04182814287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD4 PEAK1 UTRN

3.38e-04182814e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL6 CALD1 UTRN ATP2B4

3.38e-04182814ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD4 PEAK1 UTRN

3.38e-041828141710eab3037a87609d21838be2d2d29c3bc36651
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R2 PEAK1 UTRN CDH5

3.38e-0418281441b070085edba7a58b81c20aa4942d06f745acf8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRC46 CFAP36 TNNC2 IQCD

3.38e-0418281459fdffe9485b8e464c7db6b387f5a9aa8921ff06
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R2 PEAK1 UTRN CDH5

3.38e-041828145e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R2 PEAK1 UTRN CDH5

3.38e-04182814b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRANK1 BAZ1A TAOK1 UTRN

3.45e-041838148f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CCDC9B NCKAP5 PTPN21 ABCA8

3.45e-041838146821dca076318115d360ff426eb1218cfe104063
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKNOX2 UTRN CDH5 ATP2B4

3.52e-04184814087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL6 CALD1 UTRN ATP2B4

3.52e-0418481494748f63947db79a6b4540e3090a63689fdd9452
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCKAP5 PEAK1 PTPN21 UTRN

3.52e-0418481457c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

COL14A1 SETD7 UTRN ABCA8

3.52e-0418481467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKNOX2 CALD1 COL14A1 ABCA8

3.52e-04184814e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL6 CALD1 UTRN ATP2B4

3.52e-04184814819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCKAP5 PEAK1 PTPN21 UTRN

3.52e-04184814d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKNOX2 CENPT CDH5 ATP2B4

3.60e-04185814eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

KMT2D NUP155 MAST2 TFRC

3.60e-04185814a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC46 MDN1 ARMC9 RYR3

3.60e-04185814bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

PKNOX2 CALD1 NCKAP5 RYR2

3.60e-041858144905adaeeffd353e089578e5ea614437dbe794e6
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP9 STIM2 MLLT3 ATP2B4

3.60e-04185814f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUP155 ASXL3 PTPN21 CDH5

3.67e-0418681439e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 COL14A1 ABCA8 RYR2

3.67e-041868145473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

PKNOX2 CALD1 NCKAP5 RYR2

3.67e-041868148adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUP155 ASXL3 PTPN21 CDH5

3.67e-0418681402418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 CHD3 ATP2B4 RYR2

3.67e-041868147278a1a1bf9bb27aeb03852134defb31b62f30d6
Drug(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A

IPO5 PASK PDCD2 CHD3 PTPN21 MAST2 RYR2

6.83e-061988176444_DN
DrugSuramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A

PASK NCOR2 MYL6 CALD1 DTNB PTPN21 MAST2

6.83e-061988177501_DN
Drugmag-fura-2

TRPM6 ATP2B4 RYR2 RYR3

8.98e-0637814CID000123839
DrugK-Cl

MYL6 CALD1 DTNB MYO18A TNNC2 MYO15A KCNK9 ATP2B4 RYR2 RYR3

3.26e-055678110CID000004873
Drug2-hydroxycarbazole

RYR2 RYR3

3.74e-053812CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

3.74e-053812CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

3.74e-053812CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

3.74e-053812CID005748312
Drug8N3-cADPR

RYR2 RYR3

3.74e-053812CID000127713
Drugaminodantrolene

RYR2 RYR3

3.74e-053812CID009570289
DrugMgCl2

MYL6 CALD1 DTNB MYO18A USP4 TNNC2 MYO15A ATP2B4

3.78e-05354818CID000024584
DrugAC1L380G

TNNC2 RYR2 RYR3

4.03e-0519813CID000084698
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

THOC1 PASK MLXIP KAT6B MAST2 TFRC

6.20e-051918161057_DN
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A

ZKSCAN1 SPIN1 SRSF11 CHD3 PTPN21 UTRN

6.39e-051928165058_DN
Drugprochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A

PKNOX2 KMT2D CALD1 COL14A1 SRCAP ATP2B4

6.39e-051928165575_UP
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A

RALGAPA1 PASK CALD1 CHD3 PTPN21 UTRN

6.76e-051948164572_DN
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

IPO5 MAP9 PDCD2 CENPT CHD4 MAST2

6.96e-051958166561_UP
Drugdoxorubicinol

PDCD2 RYR2 TFRC

7.30e-0523813CID000083970
DrugPCB74

RYR2 RYR3

7.47e-054812CID000036218
Drug148504-47-6

RYR2 RYR3

7.47e-054812CID006444275
DrugSC 38249

RYR2 RYR3

7.47e-054812CID000134834
DrugAC1L1U7A

RYR2 RYR3

7.47e-054812CID000035682
DrugNisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A

PKNOX2 COL14A1 CD79B SRCAP UTRN RYR2

7.57e-051988166496_UP
DrugThyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A

PKNOX2 PASK PTPN21 UTRN ATP2B4 RYR2

7.78e-051998163249_UP
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

PASK CENPT ZKSCAN1 CALCOCO1 PTPN21 ATP2B4

8.00e-052008165474_DN
Drugstrontium

TNNC2 ATP2B4 RYR2 RYR3

1.02e-0468814CID000104798
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

2.07e-053782DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

2.07e-053782DOID:8545 (implicated_via_orthology)
Diseaseamino acid measurement

IPO5 PASK COL14A1 CD79B VAT1L SETD7 MLXIP RYR2 RYR3

7.52e-05678789EFO_0005134
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DTNB UTRN CAPN11

1.19e-0436783DOID:11723 (implicated_via_orthology)
DiseaseAlzheimer disease, survival time

PKNOX2 NCKAP5

1.91e-048782EFO_0000714, MONDO_0004975
Diseasegastric adenocarcinoma (is_implicated_in)

KMT2D UBR5

3.74e-0411782DOID:3717 (is_implicated_in)
DiseaseMetastatic melanoma

PASK PEAK1 ALPK2

4.00e-0454783C0278883
Diseasetestosterone measurement

TRPM6 PKNOX2 NCOR2 ERCC6L SPIN1 PTPN21 SRCAP MYO15A UTRN ATP2B4 ABCA8

5.13e-0412757811EFO_0004908
Diseaseascending aortic diameter

KLHL38 CCDC9B KCNK9 RYR2

5.27e-04140784EFO_0021787
DiseaseT-Cell Lymphoma

KMT2D ASXL3

8.08e-0416782C0079772
Diseasepulmonary hypertension (biomarker_via_orthology)

CDH5 RYR2 RYR3

1.26e-0380783DOID:6432 (biomarker_via_orthology)
Diseasecolon adenocarcinoma (is_implicated_in)

UBR5 CHD4

2.15e-0326782DOID:234 (is_implicated_in)
Diseasered blood cell density measurement

RALGAPA1 UBR5 BAZ1A CHD4 MYO15A MAST2 ATP2B4 TFRC

2.26e-03880788EFO_0007978
DiseaseRS-10-hydroxywarfarin measurement

TRPM6 VAT1L ATP2B4

2.26e-0398783EFO_0803330
DiseaseSezary Syndrome

KMT2D CHD3

2.32e-0327782C0036920

Protein segments in the cluster

PeptideGeneStartEntry
ELEEASAESEDEMIH

ACIN1

161

Q9UKV3
HMEDQSRKDFEEEDV

BDP1

751

A6H8Y1
TNGDTEDDADKMHVD

ANKRD10

241

Q9NXR5
TEHVFLLESDDEEME

ALPK2

351

Q86TB3
MGEKQEELEDLDAVH

IQCD

341

Q96DY2
IMKDLHSDDNEEESD

MLLT3

406

P42568
DGSDVVSDLEHEEMK

CFAP36

141

Q96G28
EKVSEDDMDQDFLHL

CAPN11

561

Q9UMQ6
KEELMHGEEADAVYE

PIK3AP1

406

Q6ZUJ8
AAMIEVKKDEADHDG

CDH5

706

P33151
LDKDDSKAGMEEDHT

CD79B

181

P40259
KDAEGLDEIDHAEME

ATP2B4

1071

P23634
ELHEADKGFRMDTED

ASXL3

1671

Q9C0F0
DQDMVTEDEDDPGSH

BAZ1A

726

Q9NRL2
MEQLSDEEIDHGAEE

RAPH1

1

Q70E73
AMDEDGDESIHKLKE

RBM8A

16

Q9Y5S9
DSHMESAEVEKEELP

KAT6B

1431

Q8WYB5
FDALESDHEMREEEK

KCNK9

26

Q9NPC2
EMSEHLAGFKREEEE

OTUD6A

116

Q7L8S5
SGNEEEMVEEAEALH

NCOR2

711

Q9Y618
GERDEMDLLGDHEEN

PATL1

71

Q86TB9
SDVVEALSEEHMEAD

PASK

176

Q96RG2
MEHKDDDDDDVSFAK

LNP1

1

A1A4G5
EDFDGKMHDGELEEQ

MDN1

4731

Q9NU22
KMHDGELEEQEEDDE

MDN1

4736

Q9NU22
SHMEEKDGLEDKETA

MAP9

186

Q49MG5
AGSEEDDEVVAMIKE

NFU1

161

Q9UMS0
AHAMDDIAELEEPED

MYO15A

426

Q9UKN7
HDDDKVEEMLETAHG

PPP1R2P1

166

Q96PQ5
EEDHDIMEADLDKDE

ARMC9

591

Q7Z3E5
NEMLEDEDAEDHGGT

CCDC9B

141

Q6ZUT6
TEEEVEMLVAGHEDS

MYL6

121

P60660
EALEEELDSMAKHES

PDCD2

221

Q16342
HSKEMESRDEEVEEA

MYO18A

1586

Q92614
MTLEELEDHEDEFNE

PDCL3

51

Q9H2J4
SEEDVLFSNMEEEHE

PEAK1

236

Q9H792
EDGELSEKMFHTLDE

LRRC46

31

Q96FV0
EHGEDEMDMESEKEE

PAXBP1

181

Q9Y5B6
DGSDENEMEEHELKD

DNAJC21

281

Q5F1R6
NEMEEHELKDEEDGK

DNAJC21

286

Q5F1R6
IIAEGEMHEAIKHED

IPO5

1041

O00410
ISKDLHDDDEDEEML

PPP1R2

161

P41236
ADGEFLHELEEKMEV

NUP155

1136

O75694
MLIHSSEEEEDEDFE

PTPN21

706

Q16825
HKDEDLSSLVQDDDM

MLXIP

236

Q9HAP2
EGEKEEEDDHMEYCR

CHD3

446

Q12873
DEKEMKIGETHTDIE

COL14A1

486

Q05707
LHDGVEEAEKKMEEE

CENPT

326

Q96BT3
LHSAEEGAEEEEEKM

DTNB

606

O60941
HHMDSEDEEEVSEDG

MAST2

821

Q6P0Q8
DVEEELMAKDLHFEG

EMC3

236

Q9P0I2
EVGGDLEEEDDHHME

CHD4

436

Q14839
TLDTEEEEDDTIHMG

RYR2

2371

Q92736
EEDHLKAEARGDMSE

RYR2

3336

Q92736
ESDKDALEDHMDGHF

CALCOCO1

666

Q9P1Z2
MMAAHDDSLDGTEEE

PKNOX2

421

Q96KN3
EHGLEMKTILDEGDE

JADE3

341

Q92613
HVEDMEERLDDSSEA

ERCC6L

1106

Q2NKX8
EGLFNMDEDEETEHE

RRN3

281

Q9NYV6
MDEDEETEHETKAGP

RRN3

286

Q9NYV6
KHLESSDEDEKMDEE

UTRN

1791

P46939
EGAMHEKLIHELEEE

NCKAP5

66

O14513
MDSDDEMVEEAVEGH

SETD7

1

Q8WTS6
EMVEEAVEGHLDDDG

SETD7

6

Q8WTS6
EDDTIMEELVDNHGK

NANS

341

Q9NR45
DDKSELDMMEGDHTV

TAOK1

376

Q7L7X3
EQLEGEVDHAMELSE

SRCAP

421

Q6ZRS2
GDNSHVEMKLAVDEE

TFRC

31

P02786
QKTDHVALEDEMDAD

ABCA8

446

O94911
QGSDEISHHEKMEEE

CALD1

246

Q05682
EEEMEHQEEGKEQLS

USP4

661

Q13107
EAKESHMVDDASEEL

TRPM6

651

Q9BX84
ENVTDHDISMEEGEK

RALGAPA1

466

Q6GYQ0
HDISMEEGEKREEEN

RALGAPA1

471

Q6GYQ0
RESKVNGDDHHEEDM

SRSF11

466

Q05519
HKQMDDDKDGGIEVE

STIM2

76

Q9P246
ISKDLHDDDEDEEML

PPP1R2B

161

Q6NXS1
DDEEEEEIVHMGNAI

RYR3

2271

Q15413
AVEHMFETEDGSKDE

SPIN1

136

Q9Y657
EEEDHEGDSENKERM

VAT1L

401

Q9HCJ6
HVTDEEIESLMKDGD

TNNC2

126

P02585
KMDEVIESGLVHDFD

UBP1

6

Q9NZI7
MEERKEEGEAEIQEH

TAPR1

1

Q14CZ0
VKVEEEDEEDHMWGQ

ZKSCAN1

26

P17029
GQDEMDELALEDRDH

TRANK1

2646

O15050
KHTEDREEGMDVEEG

THOC1

201

Q96FV9
QHDEHDEDGSDMELD

UBR5

1601

O95071
MDEESLDGLLFKDHD

KLHL38

1

Q2WGJ6
DEAELHEMETEKVSE

KMT2D

1066

O14686