Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

6.14e-1237948GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

7.75e-1238948GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

9.38e-1011945GO:0004523
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS12 CFLAR ERVK-6 ADAM20 CTSC ERVK-8 ERVK-19 ADAM17 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.11e-074309413GO:0004175
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

4.45e-0714944GO:0003964
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

8.03e-0737945GO:0016891
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

2.44e-0646945GO:0016893
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-8 ERVK-7 ERVK-10

2.59e-0621944GO:0035613
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS12 CFLAR ERVK-6 ADAM20 CTSC ERVK-8 ERVK-19 ADAM17 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.17e-056549413GO:0008233
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

3.01e-0538944GO:0034061
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

3.55e-0579945GO:0004521
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 NYNRIN ERVK-8 ERVK-7 PNLDC1 ERVK-10

4.45e-05136946GO:0004540
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KB2 RPS6KA6

4.53e-047942GO:0004711
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

4.60e-04136945GO:0004519
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 NYNRIN ERVK-8 ERVK-7 PNLDC1 ERVK-10

7.84e-04231946GO:0004518
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 MYL5 NEBL ERVK-8 LAMA2 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 NEB ERVK-24

9.54e-048919412GO:0005198
GeneOntologyMolecularFunctionstructural constituent of muscle

MYL5 NEBL NEB

1.09e-0343943GO:0008307
GeneOntologyBiologicalProcessDNA integration

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

2.09e-0913935GO:0015074
GeneOntologyBiologicalProcesscell-cell fusion

DOCK1 CFLAR ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9

1.12e-0785937GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

DOCK1 CFLAR ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9

1.12e-0785937GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

DOCK1 CFLAR ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9

1.54e-0789937GO:0006949
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 NYNRIN ERVK-8 ERVK-7 ERVK-10

2.46e-0648935GO:0000731
GeneOntologyBiologicalProcesscardiac muscle thin filament assembly

NEBL NEB

6.02e-053932GO:0071691
GeneOntologyBiologicalProcesstype B pancreatic cell maturation

RFX3 GDF11

1.20e-044932GO:0072560
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

CHRNA6 ERBB4 MYO5A GLUL APBA2 LAMA2 DGKE ATF4 PLCL1 ADNP JPH3

1.94e-046639311GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

CHRNA6 ERBB4 MYO5A GLUL APBA2 LAMA2 DGKE ATF4 PLCL1 ADNP JPH3

1.97e-046649311GO:0099177
GeneOntologyBiologicalProcesspositive regulation of epithelial cell proliferation

CFLAR ERBB4 ATP7A MTA3 GLUL ADAM17 ITPR1

2.21e-04270937GO:0050679
GeneOntologyBiologicalProcessviral process

ERVK-6 CANX ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

2.47e-04464939GO:0016032
GeneOntologyCellularComponentaxon

CFH NEK3 ATP7A ACADM MYO5A TIMP2 CANX GLUL CTTN ADNP DAGLA CNGA3 ATL1

1.39e-048919213GO:0030424
GeneOntologyCellularComponentsomatodendritic compartment

CFH ERBB4 ATP7A MYO5A TIMP2 CANX GLUL APBA2 LAMA2 ATF4 CTTN ADNP DAGLA CNGA3 ITPR1

2.88e-0412289215GO:0036477
GeneOntologyCellularComponentdendrite

ERBB4 ATP7A MYO5A CANX APBA2 LAMA2 ATF4 CTTN ADNP DAGLA CNGA3 ITPR1

3.76e-048589212GO:0030425
GeneOntologyCellularComponentdendritic tree

ERBB4 ATP7A MYO5A CANX APBA2 LAMA2 ATF4 CTTN ADNP DAGLA CNGA3 ITPR1

3.84e-048609212GO:0097447
MousePhenoopisthotonus

MYO5A LAMA2 ITPR1

1.05e-065673MP:0002880
DomainNEBU

NEBL NEB

1.14e-044822SM00227
DomainNebulin

NEBL NEB

1.14e-044822PF00880
DomainNebulin

NEBL NEB

1.14e-044822IPR013998
DomainNEBULIN

NEBL NEB

1.14e-044822PS51216
DomainNebulin_repeat

NEBL NEB

1.14e-044822IPR000900
DomainIntegrase_cat-core

ERVK-6 NYNRIN

1.89e-045822IPR001584
DomainINTEGRASE

ERVK-6 NYNRIN

1.89e-045822PS50994
DomainSH3_9

DOCK1 NEBL NEB CTTN

3.85e-0478824PF14604
DomaineIF5C

EIF2B5 EIF5

3.94e-047822SM00515
DomainW2

EIF2B5 EIF5

3.94e-047822PF02020
DomainW2

EIF2B5 EIF5

3.94e-047822PS51363
DomainW2_domain

EIF2B5 EIF5

3.94e-047822IPR003307
DomainPeptidase_M12B_N

ADAMTS12 ADAM20 ADAM17

6.65e-0439823IPR002870
DomainPep_M12B_propep

ADAMTS12 ADAM20 ADAM17

6.65e-0439823PF01562
DomainDISINTEGRIN_1

ADAMTS12 ADAM20 ADAM17

7.17e-0440823PS00427
DomainReprolysin

ADAMTS12 ADAM20 ADAM17

7.17e-0440823PF01421
DomainADAM_MEPRO

ADAMTS12 ADAM20 ADAM17

7.17e-0440823PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAM20 ADAM17

7.17e-0440823PS50214
DomainPeptidase_M12B

ADAMTS12 ADAM20 ADAM17

7.17e-0440823IPR001590
DomainCYSTEINE_SWITCH

ADAMTS12 ADAM20 ADAM17

7.71e-0441823PS00546
DomainDisintegrin_dom

ADAMTS12 ADAM20 ADAM17

7.71e-0441823IPR001762
DomainPept_M10_metallopeptidase

ADAMTS12 ADAM20 ADAM17

8.87e-0443823IPR001818
DomainMIF4-like

EIF2B5 EIF5

1.93e-0315822IPR016021
Domain-

EIF2B5 EIF5

1.93e-03158221.25.40.180
Domain-

ADAM20 ADAM17

3.44e-03208224.10.70.10
DomainRNaseH-like_dom

ERVK-6 NYNRIN PNLDC1

3.47e-0369823IPR012337
DomainDisintegrin

ADAM20 ADAM17

3.79e-0321822PF00200
DomainDISIN

ADAM20 ADAM17

3.79e-0321822SM00050
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

5.00e-11494410469592
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9

1.01e-101294514557543
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.93e-109494821542922
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7 ERVK-21

2.50e-10594412629516
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19 ERVK-10

7.63e-0849437983737
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.49e-071894418664271
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

3.80e-07694315063128
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19 ERVK-21

2.26e-061094312970426
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

7.23e-0629429060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

7.23e-0629429460924
Pubmed

Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor.

ERBB4 ADAM17

7.23e-06294219171023
Pubmed

Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.

TIMP2 ADAM17

7.23e-06294215308656
Pubmed

Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

NEBL NEB

7.23e-06294219851499
Pubmed

NMDA receptor-dependent recruitment of calnexin to the neuronal plasma membrane.

CANX ITPR1

2.16e-05394223851254
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

2.16e-05394210516026
Pubmed

Dissociated presenilin-1 and TACE processing of ErbB4 in lung alveolar type II cell differentiation.

ERBB4 ADAM17

2.16e-05394224462774
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

2.16e-0539429971820
Pubmed

Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.

CNGA3 ITPR1

2.16e-05394228495882
Pubmed

ErbB4 Activated p38γ MAPK Isoform Mediates Early Cardiogenesis Through NKx2.5 in Human Pluripotent Stem Cells.

ERBB4 MAPK12

2.16e-05394226418945
Pubmed

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

NEBL NEB

4.32e-05494223985323
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

MTA3 SF3A1 CHD5 EIF5 CTTN

4.48e-0514394532560809
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ERBB4 ACADM MYO5A CANX TCEAL5 PPA2 GLUL APBA2 CTTN ATL1 JPH3 ITPR1

5.80e-051139941236417873
Pubmed

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.

EIF5 ATF4

7.19e-05594227325740
Pubmed

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.

CNGA3 ITPR1

7.19e-05594226124274
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

7.19e-05594211401426
Pubmed

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone.

ERBB4 ADAM17

7.19e-05594215534001
Pubmed

MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway.

ERBB4 RPS6KB2

7.19e-05594224469061
Pubmed

Molecular analysis of viable spontaneous and radiation-induced albino (c)-locus mutations in the mouse.

ATP7A MYO5A

7.19e-0559427681531
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

EIF5 CTTN ADNP

8.96e-053294327437069
Pubmed

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

ZNF536 ERBB4 ADAM17

9.84e-053394324159190
Pubmed

CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes.

MTA3 CHD5

1.50e-04794221931736
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

MTA3 CHD5 ADNP

1.51e-043894333283408
Pubmed

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.

PNLDC1 ATL1 JPH3

1.63e-043994319724895
Pubmed

Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation.

MAPK12 ACADM ATF4

1.63e-043994318346943
Pubmed

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

ERBB4 MTA3 GLUL

1.63e-043994322802532
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

NEBL NEB

2.00e-04894211309420
Pubmed

The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system.

CANX ADAM17

2.00e-04894234613632
Pubmed

C3 Glomerulopathy

CFH DGKE

2.00e-04894220301598
Pubmed

Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip.

VRK1 CANX

2.57e-04994222572157
Pubmed

Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate.

SF3A1 CANX ADAM17 CTTN

2.84e-0411694427576135
Pubmed

INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.

ACADM MYO5A

3.91e-041194231081062
Pubmed

Genetic Atypical Hemolytic-Uremic Syndrome

CFH DGKE

3.91e-041194220301541
Pubmed

Rab27a regulates the peripheral distribution of melanosomes in melanocytes.

MYO5A CANX

3.91e-041194211266470
Pubmed

TACE is required for fetal murine cardiac development and modeling.

ERBB4 ADAM17

4.69e-041294214499647
Pubmed

Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development.

MTA3 PEG3

4.69e-041294220720167
Pubmed

Identification of epilepsy genes in human and mouse.

MYO5A ITPR1

4.69e-041294211700294
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

CFLAR MAPK12 CANX ADAM17 ATF4 CTTN

5.23e-0437194625241761
Pubmed

Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).

LAMA2 CTTN

5.53e-041394216212419
Pubmed

Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification.

GLUL GDF11

5.53e-041394231155355
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

DOCK1 PNLDC1 ATL1 JPH3

6.11e-0414294419851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

DOCK1 PNLDC1 ATL1 JPH3

6.27e-0414394420198315
Pubmed

Ischemic stroke is associated with the ABO locus: the EuroCLOT study.

CFH F13A1

6.44e-041494223381943
Pubmed

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

MIS18BP1 SF3A1

6.44e-041494210976766
Pubmed

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system.

ERBB4 LAMA2

6.44e-041494219240213
Pubmed

Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.

ACADM GLDC

6.44e-041494235727412
Pubmed

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.

CANX ATF4

7.42e-041594217090218
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

MTA3 CHD5

7.42e-041594225247294
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

NEK3 VRK1 MTA3 SF3A1 CANX RPS6KB2 CTTN ADNP F13A1

8.08e-0491094936736316
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ADAMTS12 MAPK12 ADAM20 RPS6KB2 PPA2 RPS6KA6 DGKE PLCL1

8.27e-0473094834857952
Pubmed

Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.

NEBL NEB

8.46e-041694225987543
Pubmed

Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus.

ANO2 TIMP2

9.57e-041794233084572
Pubmed

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

CTSC ATF4

9.57e-041794221795745
Pubmed

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome.

CIR1 ATF4

9.57e-041794220873783
Pubmed

An investigation into the human serum "interactome".

CFH KIAA0232 PEG3 ERVK-10

9.99e-0416294415174051
Pubmed

Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.

EIF2B5 EIF5

1.08e-031894212426392
Pubmed

Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity.

SF3A1 JPH3

1.08e-031894215527767
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

ERVK-6 ERVK-10 ANKRD55

1.12e-037594315372022
Pubmed

The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.

LAMA2 ADAM17

1.20e-031994215817462
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

MTA3 PATZ1 SF3A1 CANX CHD5 ALYREF ADNP

1.29e-0360594728977666
Pubmed

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.

VRK1 PLCL1

1.61e-032294221507922
Pubmed

PEG3 binds to H19-ICR as a transcriptional repressor.

MTA3 PEG3

1.61e-032294227824289
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

DNAH3 ALYREF DGKE CTTN CNGA3

1.73e-0331794517620599
Pubmed

Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line.

GLUL CNGA3

1.76e-032394226965927
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

EIF5 ADAM17 CTTN ATL1

1.83e-0319194431177093
Pubmed

Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.

LAMA2 ATL1

1.92e-032494224347629
Pubmed

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.

CANX ATF4

1.92e-032494219139267
Pubmed

Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.

CFLAR ATF4

1.92e-032494227106802
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

CFH NEK3 MIS18BP1 MTA3 NEBL MYO5A GLDC TCEAL5 CIR1 ADAM17

1.95e-031242941030973865
Pubmed

Gene expression analysis of the embryonic subplate.

CFH CFLAR NEBL ITPR1

2.01e-0319694421862448
Pubmed

Agrin has a pathological role in the progression of oral cancer.

CANX PPA2 EIF5 ADAM17

2.05e-0319794429872149
Pubmed

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.

PPA2 EIF5 RPS6KA6

2.08e-039394325211037
Pubmed

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.

CFLAR CANX

2.08e-032594226582200
Pubmed

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

SF3A1 ALYREF

2.08e-03259429731529
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ATP7A TYW1B DGKE ADAM17 ATL1 ITPR1

2.50e-0350494634432599
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

C1orf21 MYO5A CANX CTTN JPH3

2.55e-0334794517114649
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DOCK1 GLDC RFX3

2.56e-0310094325807483
Pubmed

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

NEB CTTN

2.61e-032894218067320
Pubmed

Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.

CANX ITPR1

2.61e-032894225332179
Pubmed

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.

CFLAR MAPK12 TIGD2 CTSC SLC35G2 ADAM17

2.65e-0351094616712791
GeneFamilyPHD finger proteins|NuRD complex

MTA3 CHD5

5.88e-04125521305
CoexpressionGSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_DN

NEK3 MTMR12 CEP162 CANX RFX3 TCTN2 ITPR1

4.23e-06199867M9543
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH SLC6A13 VRK1 MIS18BP1 F13A1 MCEMP1

4.00e-0714686645d7cb73776e60d22f335a651845e21e16948fcc
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ANO2 ZNF536 ERBB4 TIMP2 ANKRD55

1.59e-0618586616e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK1 CFH ANO2 CTSC LAMA2 ITPR1

1.98e-0619286660b1312e84f6d6448365a952469c506c00b5fe93
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TIMP2 GLUL DAGLA F13A1 MCEMP1 TCTN2

2.04e-0619386600c9c2945d2bdaa128e054cf3c59df86a279b659
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

ADAMTS12 ERBB4 NYNRIN RPS6KA6 CCDC168

1.05e-05149865d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC192 MAPK12 NYNRIN LAMA2 PLCL1

1.71e-05165865e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC192 MAPK12 NYNRIN LAMA2 PLCL1

1.71e-05165865b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC192 MAPK12 NYNRIN LAMA2 PLCL1

1.71e-05165865d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 CTSC GLUL MCMDC2 ATL1

1.87e-05168865d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH SLC6A13 C1orf21 TCEAL5 ANKRD55

2.03e-0517186538a05b5ec8ef8f09a2399994c6b4b9a707918ec1
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFH MYO5A CTSC GLUL F13A1

2.09e-051728659a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH MYO5A CTSC F13A1 MCEMP1

2.27e-05175865a8b05972e1bec4de73feaa6c4a9bcbe6b50c8044
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.40e-05177865fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 MYO5A CHD5 JPH3 ITPR1

2.46e-05178865a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 MYO5A CHD5 JPH3 ITPR1

2.46e-051788651bddbc083c36657bd6910f7466126ab325e88176
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 NEBL CTTN ATL1 TCTN2

2.53e-05179865e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 NEBL CTTN ATL1 TCTN2

2.53e-051798659863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.53e-0517986597ba67a856680f24846244c0b92c886cc0e79537
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 NEBL CTTN ATL1 TCTN2

2.53e-05179865dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH TIMP2 TCEAL5 PEG3 LAMA2

2.67e-051818653462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH TIMP2 TCEAL5 PEG3 LAMA2

2.67e-051818656730e249cac55ae892cc567d9211615882f3dab4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.74e-051828657dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.74e-05182865420a8fd30543e37a66ba0786215d056d308660d0
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZNF536 ERBB4 SLC35G2 NEB ANKRD55

2.74e-05182865b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 NEK3 ZNF536 SLC35D2 GLUL

2.81e-051838655472cdce6d99314d229418412acf1fff6340db7d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.81e-05183865e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 NEK3 ZNF536 SLC35D2 GLUL

2.89e-051848655939527d24d299e562e707469c9123890edd76be
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.96e-05185865027020754dbf71b0034791f9a34ae795e3b85f81
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.96e-05185865cefd81adb480c027545a5c78dcd05669783717f4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

2.96e-05185865bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP100 CFAP47 DNAH3 ERBB4 TCTN2

2.96e-051858655e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 NEK3 ZNF536 SLC35D2 GLUL

2.96e-051858651d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS12 C1orf21 LAMA2 PLCL1 ITPR1

3.04e-05186865cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 NEK3 ZNF536 SLC35D2 GLUL

3.04e-0518686590eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS12 CFH TIMP2 CTSC PEG3

3.04e-05186865f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 NEK3 ZNF536 SLC35D2 GLUL

3.04e-05186865bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

3.12e-05187865ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAMTS12 CHRNA6 NEBL CTSC LAMA2

3.12e-05187865a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ERBB4 SLC35D2 GLUL

3.12e-0518786597e520705491c8f52a32025311a9fa7b9176979a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

3.45e-05191865764c3a8829ae1253a0790744138266e81fc075ec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA6 ZNF536 ERBB4 TIMP2 ANKRD55

3.54e-051928653abee376c37c3646da33ac381aa63d50a01607a6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 ERBB4 NEBL GLDC PLCL1

3.62e-0519386582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL PATZ1 DGKE OGA F13A1

3.62e-05193865a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MIS18BP1 TIMP2 CTSC GLUL ADAM17

3.71e-0519486569cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

MYO5A TIMP2 CTSC GLUL F13A1

3.71e-05194865800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL PATZ1 DGKE OGA F13A1

3.81e-0519586579114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellLAM-Myeloid-Macrophage|LAM / Condition, Lineage and Cell class

TIMP2 CTSC GLUL ADAM17 MCEMP1

3.81e-0519586585abe51e47b567e6edcadfbe8cf02c2f2f0bb133
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

3.81e-05195865ec218ae03ebf8588996e86d6d9a8ea3cf71affaa
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH3 C1orf21 NEBL CTTN

3.90e-05196865af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH3 C1orf21 NEBL CTTN

3.90e-051968656d02d494196e3f857d53eea46d9419690d43beca
ToppCell(5)_Fibroblasts-(5)_Fibroblast-E|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFH C1orf21 TIMP2 GLUL LAMA2

4.00e-051978659b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCellMNPs-Macrophages|MNPs / lung cells shred on cell class, cell subclass, sample id

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.00e-0519786503d74643646dce5d3a278a1ee48c390d13a7889c
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Luminal_Macrophages|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.00e-05197865523a7f363c7ba8c196ea6e4f7544c29c18c10b51
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.00e-051978652e622d75fb45cfa80f78e1880ad056a50709895a
ToppCellLAM-Myeloid-Macrophage|Myeloid / Condition, Lineage and Cell class

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.00e-05197865355fe286609df2ded973952f1856bbc5f437cfd0
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.09e-051988653dafa555bd01e6d4b5ffbcdd542d738905140801
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIS18BP1 TIMP2 CTSC EIF5 ADAM17

4.09e-0519886593cc01d91ffc543fd1a717ef47e02e532b50b665
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.09e-051988651774dd36315a04c4cdcef2cc674204e4ab9c175b
ToppCellASK428-Immune-Macrophages|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TIMP2 CTSC CANX GLUL MCEMP1

4.09e-05198865fe7d60fa31222ec601bef1d72801803e5b549558
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.09e-05198865768df928a3265dbe7cce2acea07b2f6d6b709642
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.19e-051998655363c6df26f595f218933e38c9f628b22c6f9edd
ToppCell3'_v3-Lung-Myeloid_Mac|Lung / Manually curated celltypes from each tissue

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.19e-051998651677aaee5b7f5f262e27df5d9f1bdf6e21e3d804
ToppCell3'_v3-Lung-Myeloid_Mac-Alveolar_macrophages|Lung / Manually curated celltypes from each tissue

TIMP2 CTSC GLUL ADAM17 MCEMP1

4.19e-05199865eec1b086e5e8b9b0e1770dd269ca903f713d99a8
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIS18BP1 CTSC GLUL ADAM17 MCEMP1

4.19e-051998658e9862907b15809d083216e7d6a0f435015e5d15
ToppCellBAL-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

TIMP2 CTSC GLUL F13A1 MCEMP1

4.19e-05199865d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MYO5A TIMP2 CTSC GLUL F13A1

4.29e-0520086533c5615cbedb9e14f4433169babd3a3a51f69b4c
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

CHRNA6 ANO2 ZNF536 ERBB4 TIMP2

4.29e-05200865523d799eb315b33b77e02d5b7db63dad8450c4e1
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12|Neuronal / cells hierarchy compared to all cells using T-Statistic

CHRNA6 ANO2 ZNF536 ERBB4 TIMP2

4.29e-05200865e5cef95e563a6e793ade190ce88c999bfa0af460
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 CFH NYNRIN LAMA2 ATL1

4.29e-052008655ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellBrain_organoid-organoid_Tanaka_cellReport|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

CFH CANX LAMA2 ATF4 NEB

4.29e-05200865b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PCDH20-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK1 CHRNA6 ZNF536 ERBB4 TIMP2

4.29e-052008651d67c5d2c617749b521e70879950dea2c9d076d6
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 CFH SLC6A13 LAMA2 MGAT5B

4.29e-0520086529054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PCDH20|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK1 CHRNA6 ZNF536 ERBB4 TIMP2

4.29e-0520086526c7f2b0afe9e50f2a5c43918ad8e91d7553b72c
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CCDC192 MIS18BP1 CANX MCMDC2

6.83e-0511386479ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CCDC192 MIS18BP1 CANX MCMDC2

6.83e-0511386491d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CCDC192 MIS18BP1 CANX MCMDC2

6.83e-0511386434ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC192 ANKRD55 JPH3 TCTN2

1.65e-041428645690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VRK1 PKD1L2 F13A1 MCEMP1

1.84e-04146864d8d24851e8d8d90795a6f9378418f209200d55b1
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

OR52H1 TCEAL5 ZNF160 ITPR1

1.84e-041468645b2608b56204dda9a773988f42ff00a9fa743a39
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MIS18BP1 CTSC F13A1

1.94e-04148864bbf4933582b50b3412c805de5ed137107c996236
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MIS18BP1 CTSC F13A1

1.94e-041488646543860e3207a7de92a35bb6004be51287582f7a
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MIS18BP1 CTSC F13A1

1.94e-0414886479e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

CFH CTSC F13A1 MCEMP1

2.14e-041528649145dc014ed7f154c158d454dc2b9754396afcca
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH ZNF536 LAMA2 PNLDC1

2.20e-041538641524557514668f515ac1bbe847611f564b265b42
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ERBB4 CTSC F13A1

2.25e-0415486473de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ERBB4 CTSC F13A1

2.25e-0415486456fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH VRK1 MYO5A CTSC

2.25e-04154864c663e9834be0b45389a862dc3c13a1f988a3e5ee
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TIMP2 CTSC MCEMP1

2.37e-041568646e60e860603a7e8194f437a574ff8e887f6083b8
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VRK1 MIS18BP1 F13A1 MCEMP1

2.43e-04157864904cd98ae85ed6459e0663f077ac462842bf12df
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TYW1B ADAM17 CARNMT1 MCEMP1

2.43e-041578644183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A F13A1 MCEMP1 ITPR1

2.55e-04159864323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCelldroplet-Fat-SCAT-30m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ERBB4 CTSC F13A1

2.61e-0416086461eefe84c8e30d8a3812f5b48d26ed01739aa1ce
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7A TIMP2 ADAM17 PLCL1

2.80e-041638648dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7A TIMP2 ADAM17 PLCL1

2.80e-04163864fd243ca223079033be480a24817a399f281fa4d4
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TIMP2 CTSC F13A1

2.86e-04164864e19fc6ba049336ab989a3a968bdbefd567971d73
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TIMP2 CTSC F13A1

2.86e-04164864d6526551d0b183c3ef027ba3dbfddeac03fd93bb
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TIMP2 CTSC F13A1

2.86e-04164864eba25e4d65ca66b5192a7a4d11423f3fa0956828
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH MYO5A CTSC F13A1

2.93e-0416586447e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH MYO5A CTSC F13A1

2.93e-04165864fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VRK1 C1orf21 MTA3 ITPR1

2.93e-04165864479962ce1c3d6636ae62b6709635299748653801
DrugNSC226080

CFH CFLAR ERBB4 MAPK12 MYO5A IL36B RPS6KB2 EIF2B5 EIF5 GLUL RPS6KA6 ALYREF JPH3 ITPR1

1.30e-067828614CID000005040
Diseaseglycine measurement

SLC6A13 ERBB4 ACADM GLDC PKD1L2

4.11e-05137825EFO_0009767
Diseaseasthma, Hispanic or Latin American

CFH ERBB4

4.56e-054822HANCESTRO_0014, MONDO_0004979
Diseasemitogen-activated protein kinase 12 measurement

CFH MAPK12

4.56e-054822EFO_0020576
DiseaseMembranoproliferative Glomerulonephritis, Type I

CFH DGKE

1.14e-046822C0268742
DiseaseMembranoproliferative Glomerulonephritis, Type III

CFH DGKE

1.14e-046822C1720821
Diseasehexanoylglycine measurement

ACADM GLDC

1.59e-047822EFO_0800233
Diseasetotal blood protein measurement

CFH CFLAR DNAH3 NYNRIN PPA2 DGKE ANKRD55

2.57e-04449827EFO_0004536
DiseaseC3 glomerulopathy

CFH DGKE

2.71e-049822C4087273
DiseaseAlzheimer disease, language impairment

ERBB4 KIAA0232

2.71e-049822EFO_0005425, MONDO_0004975
DiseaseAtypical Hemolytic Uremic Syndrome

CFH DGKE

3.38e-0410822C2931788
Diseaseretinal vasculature measurement

CFH ERBB4 MYO5A GLUL LAMA2 PLCL1 ITPR1

5.96e-04517827EFO_0010554
DiseaseSchizophrenia

ADAMTS12 ERBB4 EIF5 ERVK-8 GLUL APBA2 LAMA2 ATF4 ADNP

7.69e-04883829C0036341
Diseasefactor XI measurement, Ischemic stroke

ZNF160 JPH3

1.01e-0317822EFO_0004694, HP_0002140
Diseasecoagulation factor measurement

CFH F13A1

1.40e-0320822EFO_0004634
Diseasecoronary atherosclerosis measurement, traffic air pollution measurement

DOCK1 NEBL

1.55e-0321822EFO_0007908, EFO_0007938
Diseasebeverage consumption measurement

DOCK1 VRK1 PLCL1

1.62e-0383823EFO_0010088
Diseaseatrophic macular degeneration

CFH PLCL1

2.20e-0325822EFO_1001492
Diseaseresponse to TNF antagonist, joint damage measurement

DOCK1 NEBL

2.20e-0325822EFO_0004653, EFO_0005413

Protein segments in the cluster

PeptideGeneStartEntry
VKMKEKGDIPEGYSV

TRBV28

71

A0A5B6
EKYKPGVLLGFNMKE

ADNP

816

Q9H2P0
DEKEYNADGGKMPIK

ERBB4

871

Q15303
NKEYGEDGNGKIMPA

CARNMT1

136

Q8N4J0
AQLGYMDEKDPGAQK

CHD5

1571

Q8TDI0
MKLGVAYVKGICQNP

ADAM20

306

O43506
YDPPGEKMVAAKVKG

ATF4

261

P18848
TTPGAQEGKKQYKMI

APBA2

486

Q99767
QPGDQVAMVEFKKKT

ANKRD55

396

Q3KP44
ENAIPMGEKKDVYKA

CFH

996

P08603
MPIIIAGNDQQKKKY

ACADM

131

P11310
AEKKGDEYIINGQKM

ACADM

176

P11310
KVPTKKEMYEIKAGG

ANO2

206

Q9NQ90
DGPAMKNVEFKAQKR

CFLAR

376

O15519
KMFKQKEGSGYVDIG

ADAMTS12

706

P58397
YTKGMTPVQDKEEGK

ATP7A

471

Q04656
KYMENPRGKGSQKHV

MIS18BP1

921

Q6P0N0
NKMNIGNEYKIIGIP

MCMDC2

241

Q4G0Z9
PKELVEVIKKAYMQG

ITPR1

2126

Q14643
YVEKPKLDKGQRKGM

MTMR12

541

Q9C0I1
ADQEKDKVKMKGYNP

EIF2B5

471

Q13144
DKVKMKGYNPAEVGA

EIF2B5

476

Q13144
QGKEKFLGILNKYME

MGAT5B

476

Q3V5L5
GNQGELKASMKYVKV

KIAA0232

301

Q92628
MLDPDGKGKINKEYI

MYL5

111

Q02045
YGAKKPLNTEGVMKS

F13A1

501

P00488
KLPEQFEGKKLMAYG

LAMA2

1236

P24043
RKKTGPDAGQLYAMK

RPS6KA6

91

Q9UK32
YPMAQDLGEKQKALK

GPR174

216

Q9BXC1
PGYNIEQMAKRGKKL

OSGEP

176

Q9NPF4
SPALNEFQKMYGKEK

PEG3

611

Q9GZU2
YCDGGDLMQKIKQQK

NEK3

81

P51956
KSKDKGDMEVYIQPG

PKD1L2

556

Q7Z442
AVPKNKMESDGEKKY

PATZ1

591

Q9HBE1
KDMKEGVKQYGPNSP

ERVK-10

316

P87889
KDMKEGVKQYGPNSP

ERVK-19

316

Q9YNA8
KDMKEGVKQYGPNSP

ERVK-21

316

P62683
KDMKEGVKQYGPNSP

ERVK-24

316

P63145
KDMKEGVKQYGPNSP

ERVK-6

316

Q7LDI9
KDMKEGVKQYGPNSP

ERVK-7

316

P63130
KDMKEGVKQYGPNSP

ERVK-8

316

P62685
KDMKEGVKQYGPNSP

ERVK-9

316

P63126
KDMKEGVKQYGPNSP

HERVK_113

316

P62684
QVEGKTKALLKYNGM

CHRNA6

131

Q15825
YKMPRLIAKVEGKGN

EIF5

16

P55010
KEKGNMVYLGIKGKD

IL36B

56

Q9NZH7
TYNKKMEEICGGDKP

ATL1

366

Q8WXF7
AEKPGVNEQLYKAMK

DOCK1

726

Q14185
IQKIYPANAKGMVEK

DNAH3

1231

Q8TD57
MEAYEQVQKGPLKLK

FAM32A

1

Q9Y421
NDKQQIIYGKIPGMV

GDF11

386

O95390
VMGPQEKKVVVYLQK

CTSC

56

P53634
IKPVEEVKYMKNGAE

C1orf21

36

Q9H246
GMEYKKTDAPQPDVK

CANX

511

P27824
EEEGAVMGKQVPYKK

CEP162

476

Q5TB80
KNVEPENMSGYIKQK

CFAP100

141

Q494V2
EVKMQAPAFRDKKQG

MCEMP1

11

Q8IX19
MEGLNKVLENYNKGK

DAGLA

656

Q9Y4D2
QMPYKEAKDRVKIEG

CCDC168

4876

Q8NDH2
DDMKIKGQEKYIPQV

DGKE

291

P52429
KEASGGPYEKMVLVK

CCDC192

121

P0DO97
KKIGQLIYVAEGKGM

CFAP47

2106

Q6ZTR5
EGPRENMGKAKEYLK

NYNRIN

56

Q9P2P1
NPMVYGVKTKQIRDK

OR52H1

296

Q8NGJ2
LGNMALGAPKKVKQY

MROH2A

1411

A6NES4
KKYGGLKMPTQSEEE

MTA3

411

Q9BTC8
KGIKQVYMSLPQGEK

GLUL

11

P15104
NGVYTKQKMDPKELG

SLC35D2

186

Q76EJ3
KVQGTNLGKIYAMKV

RPS6KB2

86

Q9UBS0
MQEKYTKPNGDKELS

OGA

801

O60502
QKQRYKPMQKVDGVA

RFX3

281

P48380
INEGYGNFMEENPKK

SLC35G2

41

Q8TBE7
KNGIPYMNEEQEKKI

PNLDC1

116

Q8NA58
KEPMNPIKQYVKDGK

PPA2

111

Q9H2U2
EATGMPAGKQKLQYE

SF3A1

746

Q15459
KDMKEGVKQYGPNSP

ERVK-9

316

P63128
KSPQEVKPGEKHYNM

ADAM17

286

P78536
MYEAPPGAKKENKEK

CIR1

71

Q86X95
KKGDIGKEMYIINEG

CNGA3

511

Q16281
GLLQKYMDEGNDPKI

TIGD2

341

Q4W5G0
QMKKVFGNKLYTEAP

PLCL1

506

Q15111
NYKGVLMAQKEGKRD

ZNF160

151

Q9HCG1
FGGKYGVQKDRMDKN

CTTN

306

Q14247
NGETKPVYPVMEKKE

SLC6A13

11

Q9NSD5
MEKLYKENEGKPENE

TCEAL5

1

Q5H9L2
YEIKQIKMFKGPEKD

TIMP2

71

P16035
PEKNKPGEIAKYMET

VRK1

291

Q99986
QLYGKGELPMKEKEA

ZNF536

451

O15090
DKALGYGQQIPMEEK

TTC22

181

Q5TAA0
DFGYKQGDPIMTVKK

TCTN2

276

Q96GX1
NMIKQFKGVPGVKAE

TYW1B

391

Q6NUM6
KADALKAMKQYNGVP

ALYREF

156

Q86V81
AGMKIQPVEVDKYGN

GLDC

661

P23378
MTFPDGTKEEGKYKQ

JPH3

326

Q8WXH2
DEAKNYMKGLPELEK

MAPK12

256

P53778
KMKDKGEIAQAYIGL

MYO5A

1301

Q9Y4I1
EYKKGQGIMNKEPAV

NEBL

196

O76041
YEKNKGKMIGVLSIN

NEB

601

P20929