Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRoundabout binding

MYO9B LRTM2 SLIT2 IGFALS

1.78e-06121584GO:0048495
GeneOntologyMolecularFunctionmono-olein transacylation activity

PNPLA4 PNPLA3

1.86e-0431582GO:0051264
GeneOntologyMolecularFunctiondiolein transacylation activity

PNPLA4 PNPLA3

1.86e-0431582GO:0051265
GeneOntologyMolecularFunctionendoplasmic reticulum-organelle membrane tether activity

RETREG2 RETREG1

1.86e-0431582GO:0170009
GeneOntologyMolecularFunctionendoplasmic reticulum-autophagosome adaptor activity

RETREG2 RETREG1

1.86e-0431582GO:0140506
GeneOntologyMolecularFunctionalpha2-adrenergic receptor activity

ADRA2B ADRA2C

1.86e-0431582GO:0004938
GeneOntologyMolecularFunctionautophagosome-membrane adaptor activity

RETREG2 RETREG1

1.86e-0431582GO:0160183
GeneOntologyMolecularFunctionepinephrine binding

ADRA2B ADRA2C

9.14e-0461582GO:0051379
GeneOntologyMolecularFunctionpotassium channel activator activity

LRG1 LRRC26

9.14e-0461582GO:0099104
GeneOntologyMolecularFunctionalpha-adrenergic receptor activity

ADRA2B ADRA2C

9.14e-0461582GO:0004936
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

9.40e-04551584GO:0042974
GeneOntologyCellularComponentextracellular matrix

NPHS1 PODNL1 LRRC24 LRRC32 LAMA5 LAMB3 LINGO3 CHADL OGN TRIL SLIT2 IGFALS SEMA3B SERPING1 LRRN2 GPC5 MMP9 RTN4RL2

2.72e-0665615918GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NPHS1 PODNL1 LRRC24 LRRC32 LAMA5 LAMB3 LINGO3 CHADL OGN TRIL SLIT2 IGFALS SEMA3B SERPING1 LRRN2 GPC5 MMP9 RTN4RL2

2.83e-0665815918GO:0030312
GeneOntologyCellularComponentlaminin-5 complex

LAMA5 LAMB3

3.42e-0441592GO:0005610
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

4.46e-04471594GO:0031462
GeneOntologyCellularComponentCBM complex

CARD10 CARD11

5.66e-0451592GO:0032449
Domain-

NLRP11 PODNL1 ISLR2 LRRC66 LRRC75B PRAMEF10 LRRC24 PRAMEF22 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL PRAMEF17 LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 LRRC14B IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 NLRC3 ADGRA3

8.53e-28321157343.80.10.10
DomainL_dom-like

NLRP11 PODNL1 ISLR2 LRRC66 LRRC75B PRAMEF10 LRRC24 PRAMEF22 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL PRAMEF17 LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 LRRC14B IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 NLRC3 ADGRA3

1.77e-2732815734IPR032675
DomainLRR_8

PODNL1 ISLR2 LRRC66 LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

6.77e-2717115727PF13855
DomainLRR_TYP

PODNL1 ISLR2 LRRC66 LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

1.78e-2617715727SM00369
DomainLeu-rich_rpt_typical-subtyp

PODNL1 ISLR2 LRRC66 LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

1.78e-2617715727IPR003591
DomainLeu-rich_rpt

NLRP11 PODNL1 ISLR2 LRRC66 LRRC75B LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL TPBGL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 NLRC3 ADGRA3

4.04e-2527115730IPR001611
DomainLRR_1

PODNL1 ISLR2 LRRC66 LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

1.25e-2221915726PF00560
DomainCys-rich_flank_reg_C

ISLR2 LRRC24 LINGO3 LRRC4B LRTM2 CHADL TPBGL ADGRA2 LRG1 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

1.04e-219015719IPR000483
DomainLRRCT

ISLR2 LRRC24 LINGO3 LRRC4B LRTM2 CHADL TPBGL ADGRA2 LRG1 TRIL SLIT2 IGFALS LGI3 TLR5 LRRC26 LRRN2 LRRN4 RTN4RL2 ADGRA3

1.04e-219015719SM00082
DomainLRR

PODNL1 ISLR2 LRRC66 LRRC24 LRRC32 LRRC10B PIDD1 LINGO3 LRRC4B LRTM2 CHADL LGR5 ADGRA2 OGN LRG1 LRRC47 TRIL SLIT2 IGFALS LGI3 TLR5 LRRN2 ADGRA3

9.83e-2020115723PS51450
DomainLRRNT

PODNL1 ISLR2 LRRC24 LRRC32 LINGO3 LRRC4B LRTM2 CHADL LGR5 OGN TRIL SLIT2 IGFALS LRRC26 LRRN2 RTN4RL2

1.50e-169815716IPR000372
DomainLRRNT

PODNL1 ISLR2 LRRC24 LRRC32 LINGO3 LRRC4B LRTM2 CHADL LGR5 OGN TRIL SLIT2 IGFALS LRRC26 LRRN2 RTN4RL2

1.50e-169815716SM00013
DomainLRRCT

LRRC24 TRIL SLIT2 LGI3 TLR5 ADGRA3

2.42e-07321576PF01463
DomainLRRNT

LRRC32 LINGO3 LRRC4B LRTM2 LGR5 SLIT2 IGFALS

2.89e-07531577PF01462
DomainIG

NPHS1 ISLR2 LRRC24 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 TIE1 SEMA3B LRRN2 ADGRA3

1.32e-0542115714SM00409
DomainIg_sub

NPHS1 ISLR2 LRRC24 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 TIE1 SEMA3B LRRN2 ADGRA3

1.32e-0542115714IPR003599
DomainIg-like_dom

NPHS1 ISLR2 LRRC24 HLA-DRB5 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 TIE1 SEMA3B LRRN2 ADGRA3

2.31e-0550315715IPR007110
DomainIg-like_fold

NPHS1 ISLR2 LRRC24 HLA-DRB5 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 POMGNT2 PTPRH TIE1 SEMA3B LRRN2 LRRN4 ADGRA3

2.80e-0570615718IPR013783
DomainIg_I-set

NPHS1 LRRC24 FSTL4 LINGO3 LRRC4B PTK7 NEO1 LRRN2 ADGRA3

3.35e-051901579IPR013098
DomainI-set

NPHS1 LRRC24 FSTL4 LINGO3 LRRC4B PTK7 NEO1 LRRN2 ADGRA3

3.35e-051901579PF07679
Domain-

NPHS1 ISLR2 LRRC24 HLA-DRB5 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 POMGNT2 TIE1 SEMA3B LRRN2 LRRN4 ADGRA3

4.42e-05663157172.60.40.10
DomainIG_LIKE

NPHS1 ISLR2 LRRC24 HLA-DRB5 FSTL4 LINGO3 LRRC4B PTPRU ADGRA2 PTK7 NEO1 SEMA3B LRRN2 ADGRA3

7.07e-0549115714PS50835
DomainP-loop_NTPase

SPG7 MYO1C ABCA12 MYO9B SPEF2 WRN TWNK CARD10 UPF1 ABCA7 IQGAP1 KIF20A ORC5 RAB28 AK5 CARD11 DYNC1H1 AQR

2.83e-0484815718IPR027417
DomainFN3_dom

NPHS1 PTPRU TRIL NEO1 POMGNT2 PTPRH TIE1 LRRN4

3.95e-042091578IPR003961
DomainPRAME_family

PRAMEF10 PRAMEF22 PRAMEF17

5.11e-04191573IPR026271
Domain-

ASCC1 UBASH3A

6.91e-04515723.90.1140.10
DomainPLPL

PNPLA4 PNPLA3

6.91e-0451572IPR033562
DomainDUF4704

NBEAL2 WDFY3

6.91e-0451572IPR031570
DomainDUF4704

NBEAL2 WDFY3

6.91e-0451572PF15787
DomainIGc2

NPHS1 LRRC24 FSTL4 LINGO3 LRRC4B PTK7 NEO1 LRRN2

8.54e-042351578SM00408
DomainIg_sub2

NPHS1 LRRC24 FSTL4 LINGO3 LRRC4B PTK7 NEO1 LRRN2

8.54e-042351578IPR003598
DomainPH_BEACH

NBEAL2 WDFY3

1.03e-0361572PF14844
DomainRNA_ligase/cNuc_Pdiesterase

ASCC1 UBASH3A

1.03e-0361572IPR009097
DomainReticulon

RETREG2 RETREG1

1.43e-0371572PF02453
DomainFN3

NPHS1 PTPRU NEO1 POMGNT2 PTPRH TIE1 LRRN4

1.49e-031991577PS50853
DomainPH-BEACH_dom

NBEAL2 WDFY3

1.90e-0381572IPR023362
Domain-

NBEAL2 WDFY3

1.90e-03815722.30.29.40
DomainPH_BEACH

NBEAL2 WDFY3

1.90e-0381572PS51783
DomainReticulon

RETREG2 RETREG1

1.90e-0381572IPR003388
DomainPatatin

PNPLA4 PNPLA3

2.43e-0391572PF01734
DomainBEACH

NBEAL2 WDFY3

2.43e-0391572PS50197
DomainBeach

NBEAL2 WDFY3

2.43e-0391572PF02138
Domain-

NBEAL2 WDFY3

2.43e-03915721.10.1540.10
DomainPNPLA

PNPLA4 PNPLA3

2.43e-0391572PS51635
DomainBeach

NBEAL2 WDFY3

2.43e-0391572SM01026
DomainPatatin/PLipase_A2-rel

PNPLA4 PNPLA3

2.43e-0391572IPR002641
DomainBEACH_dom

NBEAL2 WDFY3

2.43e-0391572IPR000409
DomainBiotin_lipoyl

DLAT PC

2.43e-0391572PF00364
Domainfn3

NPHS1 PTPRU NEO1 PTPRH TIE1 LRRN4

2.50e-031621576PF00041
DomainBIOTINYL_LIPOYL

DLAT PC

3.02e-03101572PS50968
DomainAdenylat/UMP-CMP_kin

SPEF2 AK5

3.02e-03101572IPR000850
DomainBiotin_lipoyl

DLAT PC

3.02e-03101572IPR000089
DomainADR_fam

ADRA2B ADRA2C

3.02e-03101572IPR002233
DomainPTPc

PTPN23 PTPRU PTPRH

3.39e-03361573SM00194
DomainGPS

PKD1L1 ADGRA2 ADGRA3

3.39e-03361573PS50221
DomainGPS

PKD1L1 ADGRA2 ADGRA3

3.67e-03371573IPR000203
Domain-

SPG7 ABCA12 SPEF2 WRN TWNK CARD10 UPF1 ABCA7 ORC5 RAB28 AK5 CARD11 DYNC1H1 AQR

4.20e-03746157143.40.50.300
DomainTYR_PHOSPHATASE_PTP

PTPN23 PTPRU PTPRH

4.27e-03391573PS50055
DomainABC_A

ABCA12 ABCA7

4.38e-03121572IPR026082
DomainSingle_hybrid_motif

DLAT PC

4.38e-03121572IPR011053
DomainQuinoprot_gluc/sorb_DH

MED16 LGI3

4.38e-03121572IPR011041
DomainFN3

NPHS1 PTPRU NEO1 PTPRH TIE1 LRRN4

4.79e-031851576SM00060
DomainPTPase_domain

PTPN23 PTPRU PTPRH

4.92e-03411573IPR000242
DomainY_phosphatase

PTPN23 PTPRU PTPRH

4.92e-03411573PF00102
DomainIBR

RNF31 CUL9

5.98e-03141572PF01485
DomainIBR

RNF31 CUL9

5.98e-03141572SM00647
DomainUBA

RNF31 SIK3 UBASH3A

6.00e-03441573IPR015940
DomainIBR_dom

RNF31 CUL9

6.86e-03151572IPR002867
DomainUBA

RNF31 SIK3 UBASH3A

7.21e-03471573PS50030
DomainLaminin_N

LAMA5 LAMB3

7.80e-03161572IPR008211
DomainLamNT

LAMA5 LAMB3

7.80e-03161572SM00136
DomainLAMININ_NTER

LAMA5 LAMB3

7.80e-03161572PS51117
DomainLaminin_N

LAMA5 LAMB3

7.80e-03161572PF00055
Domain-

NLRP11 PIDD1 CARD10 CARD11

7.86e-039315741.10.533.10
DomainGalactose-bd-like

LAMA5 CUL9 LAMB3 PTPRU

8.16e-03941574IPR008979
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MAN2A2 SPG7 LRRC24 MYO9B LAMA5 CUL9 LAMB3 TWNK PFAS GRID1 SPATA20 CARD10 ADGRA2 ABCA7 ELAC2 FAM83H POMGNT2 NBEAL2 LRP5 SAC3D1 WDFY3 FUT1 PC DYNC1H1 KLHL17

7.80e-1111051632535748872
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

ISLR2 LRRC24 LINGO3 LRRC4B ADGRA2 LRRN2 ADGRA3

2.11e-1034163718848646
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

ISLR2 LRRC24 FSTL4 LRRC4B PTPRU ADGRA2 PTK7 TIE1 SEMA3B LRRN2 ADGRA3

3.31e-101621631125826454
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ISLR2 RNF31 MYO1C ABCA12 TPRN TCP11L1 CHAF1A ASCC1 CUL9 SIK3 SUCLG1 ABCA7 FAM83H KIF20A SLIT2 SMG7 DLAT WDFY3 WDR48

1.36e-0611161631931753913
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

2.12e-0620163426694250
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

3.18e-0622163431729367
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

5.45e-0625163437451217
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ABCA12 SPEF2 LAMA5 CUL9 GRID1 ADGRA2 NEO1 LRP5

8.27e-06214163822199357
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

ADGRA2 SLIT2 TIE1 MMP9 ADGRA3

8.68e-0659163521421844
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

8.72e-0628163425089626
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

1.16e-0530163438786026
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNIK GNPTAB PTPN23 SIK3 ADGRA2 SMG7 WDFY3 WDR48

1.19e-05225163812168954
Pubmed

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

ADGRA2 LRRN4 DYNC1H1

1.62e-0511163319448619
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

2.17e-0535163419389355
Pubmed

Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c.

ADRA2B ADRA2C

2.18e-05216328670422
Pubmed

Cerebrospinal Fluid C1-Esterase Inhibitor and Tie-1 Levels Affect Cognitive Performance: Evidence from Proteome-Wide Mendelian Randomization.

TIE1 SERPING1

2.18e-052163238254961
Pubmed

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.

PTK7 MMP9

2.18e-052163227689325
Pubmed

Validation of LRG1 as a potential biomarker for detection of epithelial ovarian cancer by a blinded study.

MUC16 LRG1

2.18e-052163225799488
Pubmed

Characterization of the regulatory regions of murine alpha 2C2 adrenoceptor subtype gene.

ADRA2B ADRA2C

2.18e-05216328762185
Pubmed

IQGAP1 regulates actin cytoskeleton organization in podocytes through interaction with nephrin.

NPHS1 IQGAP1

2.18e-052163225652011
Pubmed

Urinary Matrix Metalloproteinase-9 and Nephrin in Idiopathic Membranous Nephropathy: A Cross-Sectional Study.

NPHS1 MMP9

2.18e-052163234707724
Pubmed

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.

ADRA2B ADRA2C

2.18e-05216322842764
Pubmed

Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice.

ADRA2B ADRA2C

2.18e-05216329421280
Pubmed

The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage.

CHAF1A WRN

6.53e-053163217173071
Pubmed

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

NPHS1 SRC

6.53e-053163216543952
Pubmed

Perivascular mast cells and expression of vascular endothelial growth factor, laminin-332 and matrix metalloproteinase-9 in human colorectal neoplasms.

LAMB3 MMP9

6.53e-053163235810100
Pubmed

Distribution of mRNA encoding three alpha 2-adrenergic receptor subtypes in the developing mouse embryo suggests a role for the alpha 2A subtype in apoptosis.

ADRA2B ADRA2C

6.53e-05316329415717
Pubmed

Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine.

ADRA2B ADRA2C

6.53e-053163217261653
Pubmed

Impact of flavonoids on matrix metalloproteinase secretion and invadopodia formation in highly invasive A431-III cancer cells.

SRC MMP9

6.53e-053163223991004
Pubmed

LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.

LGR5 IQGAP1

6.53e-053163228739799
Pubmed

Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells.

ADRA2B ADRA2C

6.53e-053163212946937
Pubmed

Resting sympathetic nerve activity is related to age, sex and arterial pressure but not to α2-adrenergic receptor subtype.

ADRA2B ADRA2C

6.53e-053163220613626
Pubmed

Nefopam but not physostigmine affects the thermoregulatory response in mice via alpha(2)-adrenoceptors.

ADRA2B ADRA2C

6.53e-053163219744502
Pubmed

Linkage mapping of alpha-2 adrenergic receptor genes to mouse chromosomes 2 and 5.

ADRA2B ADRA2C

6.53e-05316328281014
Pubmed

Function of brain α2B-adrenergic receptor characterized with subtype-selective α2B antagonist and KO mice.

ADRA2B ADRA2C

6.53e-053163227751959
Pubmed

Polymorphisms of adrenoceptors are not associated with an increased risk of adverse event in heart failure: a MERIT-HF substudy.

ADRA2B ADRA2C

6.53e-053163219477404
Pubmed

Characterization of SMG7 14-3-3-like domain reveals phosphoserine binding-independent regulation of p53 and UPF1.

UPF1 SMG7

6.53e-053163231511540
Pubmed

Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.

ADGRA2 ADGRA3

6.53e-053163215021905
Pubmed

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

ADRA2B ADRA2C

6.53e-053163237841583
Pubmed

Two alpha(2)-adrenergic receptor subtypes, alpha(2A) and alpha(2C), inhibit transmitter release in the brain of gene-targeted mice.

ADRA2B ADRA2C

6.53e-053163211927164
Pubmed

IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.

SRC IQGAP1

6.53e-053163219050761
Pubmed

Circulating osteoglycin and NGAL/MMP9 complex concentrations predict 1-year major adverse cardiovascular events after coronary angiography.

OGN MMP9

6.53e-053163224651681
Pubmed

Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of [alpha]2B adrenoceptors.

ADRA2B ADRA2C

6.53e-053163211125002
Pubmed

Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes.

ADRA2B ADRA2C

6.53e-053163212764077
Pubmed

Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements.

SRC SLIT2

6.53e-053163226582347
Pubmed

Characterization of the interactions of the nephrin intracellular domain.

NPHS1 IQGAP1

6.53e-053163215634346
Pubmed

Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis.

SRC MMP9

6.53e-053163230185799
Pubmed

Effect on diurnal intraocular pressure variation of eliminating the alpha-2 adrenergic receptor subtypes in the mouse.

ADRA2B ADRA2C

6.53e-053163218326714
Pubmed

Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells.

ADRA2B ADRA2C

6.53e-053163217215105
Pubmed

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.

UPF1 SMG7

6.53e-053163223348841
Pubmed

Expression of alpha 2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5' regulatory sequence for the alpha 2A AR-receptor gene in transgenic animals.

ADRA2B ADRA2C

6.53e-05316328843087
Pubmed

Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.

PNPLA4 PNPLA3

6.53e-053163216150821
Pubmed

Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice.

ADRA2B ADRA2C

6.53e-053163217075569
Pubmed

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene.

ADRA2B ADRA2C

6.53e-053163215592690
Pubmed

Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice.

ADRA2B ADRA2C

6.53e-053163210385696
Pubmed

The host nonsense-mediated mRNA decay pathway restricts Mammalian RNA virus replication.

UPF1 SMG7

6.53e-053163225211080
Pubmed

Association between common genetic variants of α2A-, α2B-, and α2C-adrenergic receptors and ischemic stroke.

ADRA2B ADRA2C

6.53e-053163222560155
Pubmed

Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission.

ADRA2B ADRA2C

6.53e-053163210647009
Pubmed

Alpha2-adrenoceptors modulating neuronal serotonin release: a study in alpha2-adrenoceptor subtype-deficient mice.

ADRA2B ADRA2C

6.53e-053163211181434
Pubmed

Insertion/insertion genotype of α(2B)-adrenergic receptor gene polymorphism is associated with silent myocardial ischemia in patients with type 2 diabetes mellitus.

ADRA2B ADRA2C

6.53e-053163220692245
Pubmed

Association between Common Genetic Variants of α2A-, α2B-, and α2C-Adrenergic Receptors and Orthostatic Hypotension.

ADRA2B ADRA2C

6.53e-053163226427149
Pubmed

Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.

RETREG2 RETREG1

6.53e-053163239039299
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF10 PRAMEF22 PRAMEF17

6.55e-0517163323565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF10 PRAMEF22 PRAMEF17

6.55e-0517163337781892
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RNF31 MYO1C MYO9B PTPN23 PFAS UPF1 OCRL ELAC2 FAM83H IQGAP1 LRRC47 KIF20A GEMIN4 DLAT WDFY3 EIF3M DYNC1H1 AQR

7.00e-0513531631829467282
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF10 PRAMEF22 PRAMEF17

7.83e-0518163323894331
Pubmed

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

PRAMEF10 PRAMEF22 PRAMEF17

7.83e-0518163339181896
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF10 PRAMEF22 PRAMEF17

7.83e-0518163312890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF10 PRAMEF22 PRAMEF17

7.83e-0518163329731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF10 PRAMEF22 PRAMEF17

7.83e-0518163314675769
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

9.05e-0550163431806660
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF10 PRAMEF22 PRAMEF17

9.27e-0519163328604677
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

NOG LAMA5 LAMB3

1.09e-0420163322911573
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF10 PRAMEF22 PRAMEF17

1.09e-0420163316580637
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF10 PRAMEF22 PRAMEF17

1.09e-0420163321425410
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PKD1L1 WRN LAMA5 PTK7 SLIT2

1.12e-04100163525807483
Pubmed

High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.

GNPTAB SRC NEO1 LRP5

1.23e-0454163426273529
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

MYO1C HGH1 TCP11L1 ZYX IQGAP1 PC DYNC1H1

1.28e-04235163728378594
Pubmed

Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells.

GPSM2 DYNC1H1

1.30e-044163223389635
Pubmed

LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis.

LGR5 GPSM2

1.30e-044163237991903
Pubmed

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway.

UPF1 SMG7

1.30e-044163215721257
Pubmed

Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response.

ADRA2B ADRA2C

1.30e-044163215920038
Pubmed

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.

LGR5 LRP5

1.30e-044163231452509
Pubmed

Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6.

UPF1 SMG7

1.30e-044163225013172
Pubmed

Dual function of focal adhesion kinase in regulating integrin-induced MMP-2 and MMP-9 release by human T lymphoid cells.

SRC MMP9

1.30e-044163216260653
Pubmed

Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling.

RNF31 CARD11

1.30e-044163231391255
Pubmed

c-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblasts.

SRC MMP9

1.30e-044163224361597
Pubmed

Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.

LAMA5 LAMB3

1.30e-044163210651091
Pubmed

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle.

GPSM2 DYNC1H1

1.30e-044163227462074
Pubmed

Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells.

SRC MMP9

1.30e-044163218061419
Pubmed

Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation.

CARD10 CARD11

1.30e-044163211356195
Pubmed

Abl interactor 1 regulates Src-Id1-matrix metalloproteinase 9 axis and is required for invadopodia formation, extracellular matrix degradation and tumor growth of human breast cancer cells.

SRC MMP9

1.30e-044163219843640
Pubmed

Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia.

NPHS1 PTPRU

1.30e-044163219528353
Pubmed

The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha2-adrenergic receptor subtypes.

ADRA2B ADRA2C

1.30e-044163210224112
Pubmed

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.

PNPLA4 PNPLA3

1.30e-044163215364929
Pubmed

Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane.

NPHS1 MYO1C

1.30e-044163221402783
Pubmed

Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16.

MUC16 TLR5

1.30e-044163225563498
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF10 PRAMEF22 PRAMEF17

1.67e-0423163319480014
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

TNIK SRC MUC16 GRID1 AASDH PTPRU PTK7 PTPRH TIE1

1.75e-04420163928065597
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TNIK PKD1L1 ETFA PPP1R13B PTPN23 OCRL SIK3 FHIP2A FAM83H IQGAP1 SMG7 PC DYNC1H1

2.05e-048531631328718761
InteractionTOP3B interactions

MAN2A2 SPG7 MYO1C LRRC24 MYO9B ETFA WRN LAMA5 CUL9 LAMB3 TWNK PFAS GRID1 SPATA20 CARD10 UPF1 ADGRA2 ABCA7 ELAC2 FAM83H IQGAP1 POMGNT2 SMG7 NBEAL2 DLAT LRP5 SAC3D1 WDFY3 FUT1 PC DYNC1H1 KLHL17

9.18e-08147015732int:TOP3B
Cytoband1p36.21

PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF17

7.75e-056316341p36.21
CytobandEnsembl 112 genes in cytogenetic band chr11q13

MOGAT2 LRRC32 TPBGL DPP3 ZDHHC24 LRP5 SAC3D1 PC

2.35e-044541638chr11q13
CytobandEnsembl 112 genes in cytogenetic band chr19p13

PODNL1 MED16 F2RL3 MYO9B CHAF1A MUC16 LINGO3 UPF1 ABCA7 LRG1

5.99e-0479716310chr19p13
Cytoband8q24.3

LRRC24 HGH1 MROH5 FAM83H

7.30e-0411316348q24.3
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRRC24 FSTL4 LINGO3 LRRC4B PTK7 NEO1 LRRN2 ADGRA3

5.13e-061611078593
GeneFamilyImmunoglobulin like domain containing

NPHS1 ISLR2 FSTL4 ADGRA2 PTK7 NEO1 TIE1 SEMA3B

1.93e-051931078594
GeneFamilyImmunoglobulin like domain containing|Adhesion G protein-coupled receptors, subfamily A

ADGRA2 ADGRA3

1.04e-0431072911
GeneFamilyPRAME family

PRAMEF10 PRAMEF22 PRAMEF17

3.73e-04241073686
GeneFamilyFibronectin type III domain containing

NPHS1 PTPRU NEO1 PTPRH TIE1 LRRN4

3.78e-041601076555
GeneFamilyMyosins, class I

MYO1C MYO1H

9.49e-04810721097
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL2 WDFY3

1.22e-03910721230
GeneFamilyAdrenoceptors

ADRA2B ADRA2C

1.22e-0391072169
GeneFamilyPatatin like phospholipase domain containing

PNPLA4 PNPLA3

1.51e-03101072466
GeneFamilyUPF1 like RNA helicases

UPF1 AQR

1.84e-031110721169
GeneFamilyLaminin subunits

LAMA5 LAMB3

2.20e-03121072626
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA7

3.01e-03141072805
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRU PTPRH

6.77e-03211072813
CoexpressionIBRAHIM_NRF2_DOWN

TNIK NOG SPG7 PIDD1 ABCA7 KIF20A NBEAL2 SEMA3B KLHL17

1.02e-061681619M42513
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

LRRC75B NOG FSTL4 GRID1 LRTM2 ADGRA2 PTGIS SLIT2 ADRA2C AK5 LGI3 MMP9

1.80e-0543816112M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

LRRC75B NOG FSTL4 GRID1 LRTM2 ADGRA2 PTGIS SLIT2 ADRA2C AK5 LGI3 MMP9

1.89e-0544016112MM832
CoexpressionDESCARTES_FETAL_SPLEEN_MESOTHELIAL_CELLS

NPHS1 LAMA5 MUC16 OGN PTGIS FAM83H BNC1 LRRN4

2.79e-051941618M40292
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

OGN PTGIS ZYX PTK7 TRIL SLIT2 NEO1 SERPING1

6.07e-0719416384f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellproximal-Endothelial-Capillary_Aerocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 LRRC32 FSTL4 CARD10 LGR5 TIE1 FUT1 PCDHGA8

6.31e-071951638f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCellproximal-Endothelial-Capillary_Aerocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 LRRC32 FSTL4 CARD10 LGR5 TIE1 FUT1 PCDHGA8

6.31e-07195163813168c9632b58dd65ecb365df3832d95e7325919
ToppCellproximal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 LRRC32 FSTL4 CARD10 LGR5 TIE1 FUT1 PCDHGA8

6.31e-07195163836b2e754ed7ff138ac05fb51f4494e5339669828
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

OGN PTGIS ZYX PTK7 TRIL SLIT2 NEO1 SERPING1

6.56e-07196163854f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 LRRC75B TPBGL ADRA2C LRRN2 LRRN4 NLRC3

3.54e-0617316370a355386210a13927ea29b10b64cb059459952d4
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 LRRC75B TPBGL ADRA2C LRRN2 LRRN4 NLRC3

3.54e-0617316373678b300cad4effd7f49bfb043305ed512693848
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 LRRC75B TPBGL ADRA2C LRRN2 LRRN4 NLRC3

3.68e-061741637aae7ab9df5a78716034ddfd5bd47adc69912d624
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 LRRC75B TPBGL ADRA2C LRRN2 LRRN4 NLRC3

3.68e-061741637d9489c4196d103ead8cb6279492bbe563a222e45
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR10 PODNL1 FSTL4 ADRA2C NBEAL2 LRRN2 LRRN4

4.60e-0618016375c649e2b3f5a53c0040b69df6e289fb3427ef2db
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MYO1C TPRN LAMA5 LAMB3 ABCA7 NBEAL2 SEMA3B

4.60e-0618016372d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

PODNL1 PLB1 NOG OGN PTGIS GGT5 SERPING1

5.50e-06185163716f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

OGN ZYX PTK7 TRIL SLIT2 NEO1 SERPING1

6.33e-061891637dc5164591dea45b420798b94dda211be03daa70c
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

MYO1C LRRC32 ADGRA2 OGN PTGIS GGT5 SERPING1

6.33e-06189163795ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

OGN ZYX PTK7 TRIL SLIT2 NEO1 SERPING1

6.55e-0619016371196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC32 OGN GGT5 TRIL TCF23 ADRA2C SERPING1

6.55e-0619016377f6dafd5418764d67f6d5ec2153233b791910e81
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

OGN ZYX PTK7 TRIL SLIT2 NEO1 SERPING1

6.78e-0619116373379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN PTGIS PTK7 GGT5 AK5 SERPING1 LRRN2

6.78e-0619116376cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN PTGIS PTK7 GGT5 AK5 SERPING1 LRRN2

6.78e-061911637850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRA2 OGN PTGIS BNC1 SEMA3B SERPING1 LRRN4

6.78e-0619116379214655dca96d766737c9f30b624d7fe7050342e
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OGN ZYX TRIL SLIT2 NEO1 SERPING1 GPSM2

6.78e-061911637a05e9a7eb137d804570dd7d8905975d735738767
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN PTGIS PTK7 GGT5 AK5 SERPING1 LRRN2

6.78e-0619116378b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OGN ZYX TRIL SLIT2 NEO1 SERPING1 GPSM2

7.02e-0619216370afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN PTGIS ZYX PTK7 SLIT2 NEO1 SERPING1

7.26e-0619316374c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN PTGIS ZYX PTK7 SLIT2 NEO1 SERPING1

7.26e-061931637ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 LAMA5 PTGIS BNC1 LRRN2 LRRN4 EIF3M

8.03e-061961637429de4119c8b2193c992d36a6af84f806730cbee
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 LAMA5 PTGIS BNC1 LRRN2 LRRN4 EIF3M

8.03e-0619616378c8a73d9d9581b8d9a9babfa93459d12fb9eb3ac
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAN2A2 TPRN CHADL SIK3 AK5 LGI3 RETREG1

8.30e-06197163782b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-|Thalamus / BrainAtlas - Mouse McCarroll V32

CCR10 MOGAT2 LRG1 TCF23 C21orf140

1.44e-0584163539196f7af1a3199ca611acbe7b2e7a76d79c8fdd
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)|Thalamus / BrainAtlas - Mouse McCarroll V32

CCR10 MOGAT2 LRG1 TCF23 C21orf140

1.44e-0584163579cdb04e91aa119a128f0fef7a09b59a0edf00a0
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--|Thalamus / BrainAtlas - Mouse McCarroll V32

CCR10 MOGAT2 LRG1 TCF23 C21orf140

1.44e-0584163566fc8327fc9c0f9a135e874ad2056ca414cd5148
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

VPS37C F2RL3 PCDHGA2 MUC16 ADGRA2 FUT1

1.78e-051481636c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GNPTAB SRC SLIT2 POMGNT2 SEMA3B RETREG1

2.14e-0515316365501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRRC75B CHADL LGR5 OGN IGFALS RTN4RL2

2.86e-0516116369703b7e67d9fadb6129cad166bd01be915042e44
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CCR10 FSTL4 LINGO3 BTG1 LRRC26 ST8SIA5

3.17e-0516416364d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOGAT2 LRRC32 OXGR1 TRIL TIE1 LRRN2

3.28e-051651636347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOGAT2 LRRC32 OXGR1 TRIL TIE1 LRRN2

3.28e-051651636507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOGAT2 LRRC32 OXGR1 TRIL TIE1 LRRN2

3.28e-05165163639a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOGAT2 LRRC32 OXGR1 TRIL TIE1 LRRN2

3.28e-0516516361890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellControl-Epithelial-Mesothelial|Control / Disease state, Lineage and Cell class

MUC16 OGN PTGIS BNC1 SLIT2 ADGRA3

3.39e-0516616361ed3788257e14f097862b999f020bfe2a57de52b
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TPBGL PTGIS BNC1 SERPING1 LRRN4

3.51e-051671636c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TPBGL PTGIS BNC1 SERPING1 LRRN4

3.51e-051671636351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

F2RL3 OXGR1 ADGRA2 TRIL TIE1 LRRN2

4.00e-05171163607ff7059071da83da1d8f266a586573920d75b58
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC16 TPBGL PTGIS BNC1 SERPING1 LRRN4

4.13e-0517216369a256db817c1af1802203cc88a55d608fb328c63
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ISLR2 F2RL3 OXGR1 ADGRA2 TRIL PCDHGA8

4.13e-051721636c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

NPHS1 LGR5 OGN BNC1 LRRN4 PCDHGA8

4.27e-0517316366989c9cebcd81eccceac7e5a86152676ee959386
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PODNL1 HTR3A OGN PTGIS ZYX SERPING1

4.41e-0517416363c47d069bd836599a8d40eae485c23d4d3487517
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLB1 F2RL3 LRRC32 SOX7 TIE1 FUT1

4.41e-05174163642735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNIK MUC16 PTGIS TCF23 ACOT11 LRRN4

4.41e-0517416364da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OGN ZYX SLIT2 NEO1 TIE1 SERPING1

4.55e-051751636282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LRRC32 LRRC10B LAMA5 OGN GGT5 SERPING1

4.70e-05176163610c1f31c27e54b70f58f0b0086ac74dee2ce4197
ToppCellEntopeduncular-Endothelial-MURAL|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LRRC32 LRRC10B LAMA5 OGN GGT5 SERPING1

4.70e-051761636b8e52bec78876562a25f0b0de502aa9372b28bd2
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 PTPRU PTGIS LRG1 TCF23 TIE1

4.70e-051761636c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 PTPRU PTGIS LRG1 TCF23 TIE1

4.70e-051761636d58ef51002ea50b3037636038214bbb7454cb503
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F2RL3 LAMA5 MUC16 SOX7 TIE1 FUT1

5.00e-051781636360d7a987f91d6d721487a921824057ec31a7332
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NPHS1 GNPTAB TPBGL AK5 LRRN4 MMP9

5.00e-051781636a28683690ab8a60eb18f3ef87ea85da4e95b22df
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC10B FSTL4 LINGO3 KCNH4 BNC1 NLRC3

5.00e-051781636a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC10B FSTL4 LINGO3 KCNH4 BNC1 NLRC3

5.00e-0517816361bddbc083c36657bd6910f7466126ab325e88176
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOG HLA-DRB5 LRRC32 PTGIS SOX7 TIE1

5.00e-051781636e2363810d77b6b245394a666eb51bacd345c43f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRA2 OGN GGT5 KIF20A TRIL SERPING1

5.16e-051791636b70509288aaf4457afd350f6c45784521337ce0d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA5 LAMB3 ABCA7 NBEAL2 SEMA3B ALPG

5.16e-051791636d5763912a4ce7188535675e338799b856edb9dda
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGA2 LRRC10B FSTL4 LINGO3 KCNH4 BNC1

5.16e-051791636a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CARD10 GGT5 SOX7 TIE1 LRRN2 FUT1

5.33e-0518016367d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1H LRRC32 LRRC10B LAMA5 LRG1 SERPING1

5.33e-051801636af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

OGN ZYX TRIL SLIT2 NEO1 SERPING1

5.33e-051801636adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1H LRRC32 LRRC10B LAMA5 LRG1 SERPING1

5.33e-051801636f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

MOGAT2 LRG1 SOX7 TCF23 TIE1

5.52e-0511116359ba3590be8862c23b6e2917caed8bdbd9f9c2753
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MOGAT2 LRG1 SOX7 TCF23 TIE1

5.52e-0511116353e38efb22c47506ef2e2c1e19c79450e11d0ce56
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MOGAT2 LRG1 SOX7 TCF23 TIE1

5.52e-051111635cd84f2a9102a6eb63226ecde11d4ece54ff99b48
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

OGN ZYX TRIL SLIT2 NEO1 SERPING1

5.66e-051821636ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN PTGIS PTK7 SLIT2 NEO1 SERPING1

5.66e-051821636c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 LGR5 ADGRA2 OGN GGT5 TRIL

5.66e-051821636b7d532feb73167e05475855061b35a209583f44c
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN PTGIS PTK7 SLIT2 NEO1 SERPING1

5.66e-051821636dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 LGR5 ADGRA2 OGN GGT5 TRIL

5.66e-051821636af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TPBGL PTGIS BNC1 SERPING1 LRRN4

5.66e-0518216369966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellBasal|World / shred by cell class for mouse tongue

MAN2A2 LAMA5 LAMB3 CARD10 ZYX PTK7

5.84e-051831636c6729a207526ff4aa48176207b9353176f631fea
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

MUC16 OGN PTGIS BNC1 SLIT2 SEMA3B

5.84e-0518316367df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR10 PODNL1 FSTL4 ADRA2C LRRN2 LRRN4

6.02e-0518416363d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR10 PODNL1 FSTL4 ADRA2C LRRN2 LRRN4

6.02e-051841636eeed75984ff111c0d1750df2f978163a42f20207
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

LRRC32 PTGIS GGT5 SOX7 TIE1 FUT1

6.20e-051851636ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

MUC16 OGN PTGIS BNC1 SLIT2 ADGRA3

6.20e-05185163623579988036fc1925992c31919750f9b3fe9f790
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

ISLR2 F2RL3 LRRC32 GGT5 SOX7 TIE1

6.20e-051851636133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 GRID1 OGN PTGIS ADRA2C MMP9

6.39e-0518616364e983de6d2515082f9e555f4f949cec84281c140
ToppCellMesenchymal_cells-Ng2+_MSCs|Mesenchymal_cells / Lineage and Cell class

PODNL1 F2RL3 PTGIS KIF20A SLIT2 MMP9

6.58e-051871636e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 LRRC32 LGR5 SOX7 ADRA2C TIE1

6.58e-051871636e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ISLR2 LRRC32 CARD10 SOX7 TIE1 NLRC3

6.58e-051871636a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

OGN ZYX TRIL SLIT2 NEO1 SERPING1

6.77e-0518816363f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F2RL3 HLA-DRB5 LRRC32 LAMA5 TIE1 FUT1

6.77e-051881636be3d287ca60ec9b42be1a8eb0a9b911c16cd8c3a
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ISLR2 LRRC32 GRID1 LRRC4B ADGRA2 SLIT2

6.77e-051881636c90669b51e1902fe7726555290c91c92a911df83
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

OGN ZYX TRIL SLIT2 NEO1 SERPING1

6.77e-0518816366740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYO1C LRRC32 LAMA5 ADGRA2 PTGIS IQGAP1

6.77e-05188163694774652fd42bad5012356672ffac8b6d2c22d37
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

MUC16 OGN PTGIS BNC1 SLIT2 ADGRA3

6.98e-05189163679bb2593ad5d17f94b17972884241f03a0f43770
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

CCR10 LRRC32 LAMA5 GRID1 LRRC4B ADRA2B

6.98e-0518916369c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PODNL1 PLB1 PTGIS GGT5 SLIT2 MMP9

6.98e-05189163646c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FSTL4 UBASH3A AK5 RETREG1 CARD11 NLRC3

7.39e-051911636133864ec1e89f97a82c3bb01d2a3c658397fefaf
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 MUC16 PTGIS BNC1 SERPING1 LRRN4

7.39e-0519116365343a527de6b0f852f45020a91f5b4869e78f13a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPHS1 LAMA5 BNC1 SEMA3B LRRN2 LRRN4

7.39e-0519116364c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OGN PTGIS PTK7 SLIT2 NEO1 SERPING1

7.39e-0519116368a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 MUC16 PTGIS BNC1 SERPING1 LRRN4

7.39e-051911636a25a5f9a380031fdaf57677a079f97a90f0550c0
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OGN PTGIS PTK7 SLIT2 NEO1 SERPING1

7.39e-051911636ce80f65bd24b1c4d2152bf45248449e7a1a97e56
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

NPHS1 PTPRU MMP9

4.59e-05141513DOID:10976 (biomarker_via_orthology)
Diseaseheart valve disease (is_marker_for)

LRP5 MMP9

7.78e-0531512DOID:4079 (is_marker_for)
DiseaseAmelogenesis imperfecta

LAMB3 FAM83H ACP4

8.48e-05171513cv:C0002452
DiseaseHereditary hearing loss and deafness

TPRN TWNK SUCLG1 DLAT GPSM2 PC

1.09e-041461516cv:C0236038
DiseaseMitochondrial disease

TWNK SUCLG1 DLAT PC

1.17e-04491514cv:C0751651
DiseaseInhalant adrenergic use measurement

SPEF2 HLA-DRB5 MUC16 CHADL CARD11

1.38e-04961515EFO_0009941
DiseaseLupus Nephritis

SERPING1 MMP9

1.55e-0441512C0024143
Diseasepolypeptide N-acetylgalactosaminyltransferase 1 measurement

HLA-DRB5 SIK3

2.58e-0451512EFO_0801899
DiseaseAmelogenesis imperfecta type 1

LAMB3 ACP4

2.58e-0451512cv:C0399367
DiseaseAmelogenesis imperfecta local hypoplastic form

LAMB3 ACP4

5.37e-0471512C0399367
Diseasecholine measurement

PLB1 MOGAT2 MYO1H HLA-DRB5 SIK3

5.62e-041301515EFO_0010116
DiseaseLeigh syndrome

DLAT PC

7.14e-0481512cv:C0023264
Diseasebrain ischemia (implicated_via_orthology)

SRC PTGIS MMP9

7.62e-04351513DOID:2316 (implicated_via_orthology)
Diseasealcoholic liver disease

HTR3A TCP11L1 PNPLA3 ADGRA3

8.46e-04821514EFO_0008573
Diseasecathepsin F measurement

GNPTAB ZDHHC24

9.15e-0491512EFO_0022038
DiseaseSpastic Paraplegia

SPG7 WDR48

9.15e-0491512C0037772
DiseaseMitochondrial DNA Deletion Syndromes

TWNK SUCLG1

9.15e-0491512cv:CN043632
Diseaseage at menopause

NLRP11 LRRC66 ADGRA2 BNC1 LRRN4 EIF3M DYNC1H1

9.66e-043021517EFO_0004704
Diseasesex interaction measurement, longitudinal BMI measurement

WRN GPC5

1.14e-03101512EFO_0005937, EFO_0008343
Diseasecystic kidney disease (implicated_via_orthology)

LAMA5 SLIT2

1.14e-03101512DOID:2975 (implicated_via_orthology)
Diseasephospholipids:total lipids ratio

ANKRD31 MOGAT2 HLA-DRB5 ETFA SIK3 PNPLA3

1.14e-032271516EFO_0020946
DiseaseLiver carcinoma

MOGAT2 ETFA IQGAP1 KIF20A SLIT2 ADRA2B IGFALS MMP9 NLRC3

1.25e-035071519C2239176
Diseasesusceptibility to infectious disease measurement

FSTL4 ELAC2 SLIT2

1.30e-03421513EFO_0008422
Diseasepolymyositis (is_marker_for)

SLIT2 MMP9

1.39e-03111512DOID:0080745 (is_marker_for)
Diseasemonocyte percentage of leukocytes

SPEF2 HLA-DRB5 ETFA DLEU1 ZYX GGT5 ADRA2B PTPRH TLR5 PNPLA3 WDFY3

1.40e-0373115111EFO_0007989
Diseaseeosinophil percentage of leukocytes

PLB1 SPEF2 HLA-DRB5 LRRC32 DLEU1 SIK3 UBASH3A ABCA7 GGT5 AK5 CARD11

1.64e-0374615111EFO_0007991
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

FKRP POMGNT2

2.27e-03141512C1836373
Diseasealpha-Dystroglycanopathies

FKRP POMGNT2

2.27e-03141512C2936406
DiseaseFukuyama Type Congenital Muscular Dystrophy

FKRP POMGNT2

2.27e-03141512C0410174
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

SERPING1 MMP9

2.27e-03141512DOID:898 (is_marker_for)
DiseaseMuscle eye brain disease

FKRP POMGNT2

2.27e-03141512C0457133
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

FKRP POMGNT2

2.27e-03141512C4284790
Diseaseheel bone mineral density, urate measurement

ANKRD31 DLEU1 WRN IQGAP1 ACP4

2.50e-031821515EFO_0004531, EFO_0009270
Diseaserelapsing-remitting multiple sclerosis (is_marker_for)

NOG MMP9

2.61e-03151512DOID:2378 (is_marker_for)
DiseaseWalker-Warburg congenital muscular dystrophy

FKRP POMGNT2

2.61e-03151512C0265221
Diseaserheumatoid arthritis

VPS37C HLA-DRB5 SRC FSTL4 UBASH3A TXNDC11 IQGAP1 GPC5

2.70e-034621518EFO_0000685
Diseasephospholipids in medium HDL measurement

MOGAT2 MYO1H SIK3

2.84e-03551513EFO_0022295
Diseaselevel of triacylglycerol (56:6) in blood serum

SIK3 PNPLA3

2.98e-03161512OBA_2020007
Diseasetotal lipids in medium HDL measurement

MOGAT2 MYO1H SIK3

3.30e-03581513EFO_0022310
Diseasefree cholesterol in medium HDL measurement

MOGAT2 MYO1H SIK3

3.30e-03581513EFO_0022267
Diseasedermatomyositis (is_marker_for)

SLIT2 MMP9

3.36e-03171512DOID:10223 (is_marker_for)
Diseaseatrophic macular degeneration, age-related macular degeneration, wet macular degeneration

SPEF2 MMP9 SLC16A8

3.63e-03601513EFO_0001365, EFO_0004683, EFO_1001492
Diseasefree cholesterol in HDL measurement

MOGAT2 MYO1H SIK3

3.81e-03611513EFO_0022264
Diseasephospholipids in HDL measurement

MOGAT2 MYO1H SIK3

3.81e-03611513EFO_0022293
Diseasetotal lipids in HDL measurement

MOGAT2 MYO1H SIK3

4.17e-03631513EFO_0022307
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

SPEF2 SLIT2

4.20e-03191512DOID:9562 (implicated_via_orthology)
Diseasesexual dimorphism measurement

ANKRD31 LRRC66 NOG SPG7 MYO9B ETFA DLEU1 PTPN23 SIK3 AK5 CARD11 MMP9 PC

4.59e-03110615113EFO_0021796
Diseasejuvenile dermatomyositis

HLA-DRB5 ADRA2B

4.65e-03201512EFO_0000557
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

MOGAT2 MYO1H ETFA SIK3 PNPLA3 MMP9

4.80e-033031516EFO_0004612, EFO_0020945
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

MOGAT2 SIK3 PNPLA3

4.95e-03671513EFO_0008595, EFO_0020946
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

MOGAT2 MYO1H HLA-DRB5 ETFA SIK3 MMP9

5.11e-033071516EFO_0004612, EFO_0020946

Protein segments in the cluster

PeptideGeneStartEntry
PSRLLELAGQSLLRN

PRAMEF33

6

A0A0G2JMD5
SPLLRNVIIRSQFDG

C21orf140

6

B9A014
RNLLDLPSSRLDFQV

CARD10

861

Q9BWT7
LLALPALLFSQDGQR

CCR10

171

P46092
SQNLLLRSPGFRQLC

COX18

291

Q8N8Q8
PGLLANFTLLRTLDL

LRG1

181

P02750
TFQGLPRLLRLNISG

ADGRA2

151

Q96PE1
PRLLRLNISGNIFSS

ADGRA2

156

Q96PE1
DSLARGSPENLRLLQ

ABCA12

386

Q86UK0
GSPENLRLLQSTIRF

ABCA12

391

Q86UK0
FSGLSLLERLDLRNN

ADGRA3

101

Q8IWK6
VLTSRALRAPQNLFL

ADRA2C

76

P18825
ALRAPQNLFLVSLAS

ADRA2C

81

P18825
ALLLPTLLAQGEARR

HTR3A

11

P46098
QRLLAGGLFSALSNR

BNC1

676

Q01954
DFLRGNPNLSLRIFT

AICDA

96

Q9GZX7
AAQAFLLLSDLRQRP

ACOT11

436

Q8WXI4
PALASLGLSNNRLSR

IGFALS

146

P35858
RSLRAPQNLFLVSLA

ADRA2B

41

P18089
DGRNILKSFALLPRL

ASCC1

341

Q8N9N2
REGPALLLLSRFSQA

ARMC5

521

Q96C12
LQATPTLLRRFGSQL

AASDH

286

Q4L235
LLLQNPQDGFSRLKR

AQR

1076

O60306
GPLDNFLRNRIETSI

CHAF1A

96

Q13111
PFLLNFLREQSSRVL

CDAN1

51

Q8IWY9
GLRVRFNPLALLLDA

PPP1R13B

881

Q96KQ4
PGRLSNFNDSLVSRL

ABCA7

91

Q8IZY2
DALGALPDLRSLRIN

ISLR2

141

Q6UXK2
NNRLRTLAPGTFDAL

ISLR2

156

Q6UXK2
ALALFRALQSPALGL

IQGAP1

321

P46940
FLQNNLIRTLRPGTF

RTN4RL2

66

Q86UN3
GLDFFLRRITLPGNL

RAB28

46

P51157
RSQLFALNPRSGSLV

PCDHGA2

71

Q9Y5H1
RTQLFALNPRSGSLI

PCDHGA8

71

Q9Y5G5
LRLLSGPLDQVRAAL

PTPN23

526

Q9H3S7
FLSALSPLGQQLLER

SLC16A8

156

O95907
AELLLLNGADPLFRN

ANKRD31

571

Q8N7Z5
FPGDLRTNLTDRQLA

MMP9

31

P14780
LQGLLKPLFRNSSLE

MUC16

12106

Q8WXI7
LANASALRPGDALNL

NPHS1

551

O60500
PSRLLELAGQSLLRN

PRAMEF17

6

Q5VTA0
DQRASFSNLPGLRLT

GPSM2

561

P81274
LALAGDTRPRFLQQD

HLA-DRB5

26

Q30154
FLSGLLSPRVNALLA

NLRC3

516

Q7RTR2
PNSLGVSERLQRLTF

GNPTAB

776

Q3T906
ARREIPQLFESLLNG

AK5

11

Q9Y6K8
GRVLLFSPTLRQLDL

NLRP11

796

P59045
GRSLLPSRTFLQALN

GPC5

216

P78333
LQSLNLSGNRLRELP

LRRC47

131

Q8N1G4
IAPRAFSGLSNLLRL

LRRN2

156

O75325
GERPSLRLQLLSNLF

EIF3M

96

Q7L2H7
ASPLLLFANRRDVRL

LRP5

31

O75197
RLVELLPFSSALQGL

DLEU1

16

O43261
LQPGTALFSRRQLFL

RABIF

31

P47224
GATPRNRLLLQLLGS

DLAT

66

P10515
PRSILRSSLNFFLGN

PNPLA3

446

Q9NST1
LSLANLVRLNQALFP

PNPLA4

211

P41247
RAALGLRLLPNLTAQ

KDM4E

366

B2RXH2
FRAGLPRDLTFNLRQ

KCNH4

676

Q9UQ05
ALPRLTQLLLNGNRL

LRRC75B

206

Q2VPJ9
AGAFRAQPRLLELAL

LRRC24

91

Q50LG9
AQPRLLELALTSNRL

LRRC24

96

Q50LG9
ASLEDQNFRRLPGLL

LINGO3

211

P0C6S8
DIPNLRRLDFTGNLI

OGN

141

P20774
ALLSRLFRAQDPDQL

DPP3

61

Q9NY33
RLLALPADFAQLQSL

LRRC10B

101

A6NIK2
RQLKFLGNPLSARAL

LRRC14B

391

A6NHZ5
LNGGFNLSRILRTAL

TWNK

346

Q96RR1
NLGSRRFQPALLDLS

POMGNT2

106

Q8NAT1
RLAASLDGARTPLLQ

LAMA5

2456

O15230
DLLSIQQPRLSGARA

LRRC66

631

Q68CR7
LARNLQRLFGFQPLA

HPDL

21

Q96IR7
LYLLASLPNQGSLLR

MED16

626

Q9Y2X0
RFLLQRQSGALVPAA

PTPRU

221

Q92729
VSRPLAALNTFGNLL

OXGR1

286

Q96P68
ALALPLTLQRQTFRL

F2RL3

206

Q96RI0
LDLRNNSFSLLPGSA

LRRC32

541

Q14392
ALDARPGSFTLLLRN

MOGAT2

191

Q3SYC2
ILANFSRVQRLGLPL

ACP4

266

Q9BZG2
QFLPRSLRVADLAAN

PODNL1

141

Q6PEZ8
TEAALLLLSRNPRGF

ALPG

311

P10696
LAGLPNLNSARVELF

OR6S1

16

Q8NH40
IGFLNDPRRLNVALT

UPF1

861

Q92900
LPAASLLQLNGVRDA

KLHL17

166

Q6TDP4
SLSLNRFRLALPESN

BPIFC

401

Q8NFQ6
LTPARESLFLINGRQ

FSTL4

806

Q6MZW2
STLRQLFFNGTEPLR

GGT5

196

P36269
LLLLLAGDRASSNPN

SERPING1

11

P05155
SQLFRSNVLLVPLGD

MAN2A2

411

P49641
NNFLARLRSIPLDEG

DYNC1H1

2376

Q14204
RGLQSFLDQASRLGL

GRID1

176

Q9ULK0
LSLRRTLQGLQLDLP

LAMB3

656

Q13751
PSASRVILLENLNRF

CUL9

1256

Q8IWT3
RLQSDFAALLTGPLQ

CENPO

196

Q9BU64
LLLLPQAFSRQGRTL

DCST2

81

Q5T1A1
LVNSLLNLTRSPDGR

FHIP2A

261

Q5W0V3
LLRARDLFNLSAPLA

FKRP

201

Q9H9S5
FRGLGRLLLLNLASN

CHADL

106

Q6NUI6
RGFPSDTQLLDLRRN

CHADL

421

Q6NUI6
LELQLSGNPLRALRD

CHADL

596

Q6NUI6
GLAKQDSFRSRLNPL

FAM83H

661

Q6ZRV2
EGNAARLFRLLQTLP

SAC3D1

271

A6NKF1
LLASPGAQLLSLLFR

PKD1L1

2001

Q8TDX9
SPRLSRASFLFGQLL

CARD11

886

Q9BXL7
NLGFLLPRSCLELNI

MAP3K19

156

Q56UN5
LSGNRLDLIRPGSFQ

LRRC4B

236

Q9NT99
SSLRALALAGNPLRA

LRRN4

146

Q8WUT4
LPSLRFLEELRLAGN

LGR5

86

O75473
SNRLQSLPASLAGLR

PIDD1

226

Q9HB75
SNLSQRPAARAFLLD

HGH1

181

Q9BTY7
LAELDQLLRQRPSGA

NOG

101

Q13253
SLLQGQLRPLLDGFF

MROH5

1076

Q6ZUA9
ALAQLNGRRAFILPA

FUT1

101

P19526
LLSFLLPGHTRLRNQ

TCP11L1

141

Q9NUJ3
NNFSRLEPTLNLLGV

SPEF2

61

Q9C093
PGFLLSSLSRDQNAL

SOX7

131

Q9BT81
SERLLLNAENPRGTF

SRC

161

P12931
LSAFALLPLQGGRDR

TMEM200C

376

A6NKL6
RLDLSNNFLDRLPRS

LRTM2

96

Q8N967
NNFLDRLPRSIFGDL

LRTM2

101

Q8N967
RPLRSLLGFVAANLL

RETREG1

91

Q9H6L5
NLRRGDRLLLFPFLS

PTGIS

376

Q16647
NLLPGFLRLQELADR

ORC5

136

O43913
APGQLRRAASLLRFQ

ETFA

6

P13804
SLPTAELRLFLAQRL

NBEAL2

461

Q6ZNJ1
QAPRRLLELAGQSLL

PRAMEF22

6

A3QJZ6
LQGFLALRPSFRNLD

SMG7

421

Q92540
TFLNLVSDDRRQLLP

NEO1

91

Q92859
LLGRPQALSRQALDS

RETREG2

371

Q8NC44
LPFDGSTLQNLRARV

SIK3

261

Q9Y2K2
PSANRDLLGSRTLLF

ST8SIA5

6

O15466
LPILFLRGSNSQRLA

WRN

981

Q14191
TLPNILREFNRNLTG

PLB1

786

Q6P1J6
GGRALQSLQLRLLTP

SPG7

56

Q9UQ90
PSDRQRAIQFLLGFL

OCRL

881

Q01968
LAAARLLSRSFLLPQ

SUCLG1

21

P53597
LLSRSFLLPQNGIRH

SUCLG1

26

P53597
NILGINFLGRRLSLS

SVOPL

361

Q8N434
RIGLSSQELFRLLPS

BTG1

86

P62324
GLRRRSPAFLLSANQ

PRDM10-DT

21

Q96N53
GQAFSLEQLRPLLAS

RNF31

26

Q96EP0
ILNLPGESTLRRDFL

TNIK

341

Q9UKE5
GTPSLLRFALASLLQ

ZSWIM9

266

Q86XI8
LQLDPALNRLFTAGR

WDR48

36

Q8TAF3
SFLLQGFPSSNDLLR

WDFY3

1571

Q8IZQ1
PSILLQRERALASLG

ELAC2

556

Q9BQ52
PRSLALIFNSLQGQL

KIF20A

181

O95235
AVEQGFTQPLRRLSL

SEMA3B

646

Q13214
TLLANLRLTDPQRFF

TIE1

26

P35590
QLPFLSTLRRLEDQA

SPATA20

746

Q8TB22
ESNALLLRSPNRDFL

PFAS

561

O15067
RFLNLSANELQPSLR

TRIL

206

Q7L0X0
ELRLEGNRLSQLPTA

TRIL

281

Q7L0X0
PSRLLELAGQSLLRN

PRAMEF10

6

O60809
PDAFQGLRSLNSLVL

SLIT2

341

O94813
LGPLARALQLALAAF

ZDHHC24

46

Q6UX98
FSLRSPVLDLFQGQL

TXNDC11

101

Q6PKC3
PLGDLQARALASLRA

TPRN

311

Q4KMQ1
LARAQPAVRALGQLF

ZYX

391

Q15942
GAFRGLPALRSLQLN

TPBGL

136

P0DKB5
TLRQAFLALQAALPA

TCF23

91

Q7RTU1
FRNLPNLRILDLGSS

TLR5

91

O60602
NRSLAERNLEFQGPL

VPS37C

46

A5D8V6
LLRQLQSEGLLGPFS

PTPRH

1036

Q9HD43
FANGSLLLTQVRPRN

PTK7

281

Q13308
TFGPLDSLNTRLFLQ

PC

1026

P11498
GPNLRLSNLTRASFV

UBASH3A

201

P57075
LGSNRALFRQPDLVL

GEMIN4

441

P57678
PLRALRNLSLAGNRL

LRRC26

141

Q2I0M4
FRPLDILNDLDLRGN

LGI3

156

Q8N145
RDRLLQSNPVLEAFG

MYO1C

171

O00159
SLQIARDRLLFSNPV

MYO1H

131

Q8N1T3
QGEDPRSLLQSLSRL

MYO9B

756

Q13459