Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 FZD7 FZD8 FZD2

2.08e-0717634GO:0042813
GeneOntologyMolecularFunctionWnt-protein binding

FZD1 FZD7 FZD8 FZD2

3.89e-0634634GO:0017147
GeneOntologyMolecularFunctionlong-chain fatty acid transmembrane transporter activity

ABCD3 ABCD1 ABCD2

2.36e-0518633GO:0005324
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

ABCD3 ABCD1 ABCD2

5.07e-0523633GO:0015245
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

ABCD3 ABCD1 ABCD2

8.29e-0527633GO:0047617
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ABCD3 ABCD1 ABCD2

9.27e-0528633GO:0016289
GeneOntologyMolecularFunctionthiolester hydrolase activity

ABCD3 ABCD1 ABCD2

4.40e-0447633GO:0016790
GeneOntologyMolecularFunctionABC-type transporter activity

ABCD3 ABCD1 ABCD2

4.97e-0449633GO:0140359
GeneOntologyMolecularFunctionPDZ domain binding

FZD1 FZD7 FZD8 FZD2

6.17e-04123634GO:0030165
GeneOntologyMolecularFunctionactin filament binding

MICAL1 NRAP SPTB NEB CTTN

7.47e-04227635GO:0051015
GeneOntologyMolecularFunctionactin binding

MICAL1 NRAP SPTB TRPC5 KCNMA1 NEB CTTN

7.59e-04479637GO:0003779
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 SORL1

1.14e-0316632GO:0005041
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCD3 ABCD1 ABCD2

1.59e-0373633GO:0170055
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 SORL1

1.98e-0321632GO:0030228
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCD3 ABCD1 ABCD2

2.89e-0390633GO:0008028
GeneOntologyBiologicalProcesslong-chain fatty acid import into peroxisome

ABCD3 ABCD1 ABCD2

1.03e-074623GO:0015910
GeneOntologyBiologicalProcessregulation of fatty acid beta-oxidation

MTOR DBI ABCD1 ABCD2

7.52e-0724624GO:0031998
GeneOntologyBiologicalProcessvery long-chain fatty acid catabolic process

ABCD3 ABCD1 ABCD2

8.97e-077623GO:0042760
GeneOntologyBiologicalProcessfatty acid catabolic process

MTOR ABCD3 DBI ABCD1 ABCD2 PCK1

1.32e-06116626GO:0009062
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

FZD1 FZD7 FZD8 RNF213 FZD2

3.48e-0677625GO:0035567
GeneOntologyBiologicalProcessregulation of lipid catabolic process

MTOR DBI ABCD1 ABCD2 SORL1

3.71e-0678625GO:0050994
GeneOntologyBiologicalProcessfatty acid beta-oxidation

MTOR ABCD3 DBI ABCD1 ABCD2

4.21e-0680625GO:0006635
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

MTOR ABCD3 DBI ABCD1 ABCD2 PCK1

4.84e-06145626GO:0072329
GeneOntologyBiologicalProcessregulation of cellular component size

MTOR SPTB TRPC5 KCNMA1 LRP1 NEB CTTN HCK SLC12A5

4.84e-06426629GO:0032535
GeneOntologyBiologicalProcessregulation of fatty acid oxidation

MTOR DBI ABCD1 ABCD2

1.10e-0546624GO:0046320
GeneOntologyBiologicalProcesslipid catabolic process

MTOR ABCD3 LRP1 DBI ABCD1 ABCD2 PCK1 SORL1

1.82e-05382628GO:0016042
GeneOntologyBiologicalProcesscardiac muscle thin filament assembly

NRAP NEB

2.66e-053622GO:0071691
GeneOntologyBiologicalProcesspositive regulation of lipid biosynthetic process

MTOR DBI ABCD1 ABCD2 PCK1

3.17e-05121625GO:0046889
GeneOntologyBiologicalProcessregulation of lipid metabolic process

MTOR KCNMA1 RNF213 DBI ABCD1 ABCD2 PCK1 SORL1

3.28e-05415628GO:0019216
GeneOntologyBiologicalProcessfatty acid oxidation

MTOR ABCD3 DBI ABCD1 ABCD2

3.30e-05122625GO:0019395
GeneOntologyBiologicalProcesscardiac myofibril assembly

NRAP OBSL1 NEB

3.31e-0521623GO:0055003
GeneOntologyBiologicalProcessperoxisomal membrane transport

ABCD3 ABCD1 ABCD2

3.82e-0522623GO:0015919
GeneOntologyBiologicalProcessperoxisomal transport

ABCD3 ABCD1 ABCD2

3.82e-0522623GO:0043574
GeneOntologyBiologicalProcessfatty acid transmembrane transport

ABCD3 ABCD1 ABCD2

3.82e-0522623GO:1902001
GeneOntologyBiologicalProcesslipid oxidation

MTOR ABCD3 DBI ABCD1 ABCD2

4.31e-05129625GO:0034440
GeneOntologyBiologicalProcesslipid modification

MTOR ABCD3 RNF213 DBI ABCD1 ABCD2

4.41e-05214626GO:0030258
GeneOntologyBiologicalProcessregulation of cell size

MTOR TRPC5 KCNMA1 LRP1 CTTN SLC12A5

5.82e-05225626GO:0008361
GeneOntologyBiologicalProcessnegative regulation of Ras protein signal transduction

RASA4 RASA4B RASAL1

8.03e-0528623GO:0046580
GeneOntologyBiologicalProcessregulation of anatomical structure size

MTOR SPTB TRPC5 KCNMA1 LRP1 NEB CTTN HCK SLC12A5

9.03e-05618629GO:0090066
GeneOntologyBiologicalProcesssupramolecular fiber organization

MICAL1 B4GALT7 NRAP MTOR SPTB CKAP5 OBSL1 NEB CTTN HCK P3H4

1.17e-049576211GO:0097435
GeneOntologyBiologicalProcessmuscular septum morphogenesis

FZD1 FZD2

1.32e-046622GO:0003150
GeneOntologyBiologicalProcessresponse to methionine

MTOR PCK1

1.32e-046622GO:1904640
GeneOntologyBiologicalProcesspositive regulation of lipid metabolic process

MTOR DBI ABCD1 ABCD2 PCK1

1.38e-04165625GO:0045834
GeneOntologyBiologicalProcessvery long-chain fatty acid metabolic process

ABCD3 ABCD1 ABCD2

1.58e-0435623GO:0000038
GeneOntologyBiologicalProcessorganic acid catabolic process

MTOR ABCD3 DBI ABCD1 ABCD2 PCK1

1.65e-04272626GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

MTOR ABCD3 DBI ABCD1 ABCD2 PCK1

1.65e-04272626GO:0046395
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

FZD7 NRAP MTOR OBSL1 NEB

1.92e-04177625GO:0055007
GeneOntologyBiologicalProcessregulation of actin filament length

MTOR SPTB NEB CTTN HCK

2.07e-04180625GO:0030832
GeneOntologyBiologicalProcessperoxisome organization

ABCD3 ABCD1 ABCD2

2.19e-0439623GO:0007031
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

MTOR CKAP5 CTTN HCK

2.52e-04102624GO:0032273
GeneOntologyBiologicalProcessregulation of ketone metabolic process

MTOR KCNMA1 DBI ABCD1 ABCD2

2.60e-04189625GO:0010565
GeneOntologyBiologicalProcessdevelopmental cell growth

MTOR TRPC5 LRP1 PRMT2 CTTN RASAL1

2.84e-04301626GO:0048588
GeneOntologyBiologicalProcessresponse to osmotic stress

MTOR KCNMA1 PCK1 SLC12A5

3.73e-04113624GO:0006970
GeneOntologyBiologicalProcessmembranous septum morphogenesis

FZD1 FZD2

3.94e-0410622GO:0003149
GeneOntologyBiologicalProcesshard palate development

FZD1 FZD2

3.94e-0410622GO:0060022
GeneOntologyBiologicalProcessfatty acid metabolic process

MTOR AACS ABCD3 DBI ABCD1 ABCD2 PCK1

4.53e-04461627GO:0006631
GeneOntologyBiologicalProcesspositive regulation of unsaturated fatty acid biosynthetic process

ABCD1 ABCD2

4.80e-0411622GO:2001280
GeneOntologyBiologicalProcesscardiac muscle cell development

NRAP MTOR OBSL1 NEB

4.99e-04122624GO:0055013
GeneOntologyBiologicalProcesscardiocyte differentiation

FZD7 NRAP MTOR OBSL1 NEB

5.32e-04221625GO:0035051
GeneOntologyBiologicalProcessactin polymerization or depolymerization

MICAL1 MTOR SPTB CTTN HCK

5.43e-04222625GO:0008154
GeneOntologyBiologicalProcessintracellular lipid transport

ABCD3 ABCD1 ABCD2

5.44e-0453623GO:0032365
GeneOntologyBiologicalProcessneuron projection organization

CKAP5 ABCD1 CTTN ABCD2

5.80e-04127624GO:0106027
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

FZD1 FZD7 FZD2

6.07e-0455623GO:0060071
GeneOntologyBiologicalProcessresponse to hypoxia

MTOR KCNMA1 PRMT2 PYGM PCK1 DNMT3A

6.13e-04348626GO:0001666
GeneOntologyBiologicalProcessactin cytoskeleton organization

MICAL1 NRAP MTOR SPTB OBSL1 LRP1 NEB CTTN HCK

6.26e-04803629GO:0030036
GeneOntologyBiologicalProcessregulation of protein polymerization

MTOR SPTB CKAP5 CTTN HCK

6.50e-04231625GO:0032271
GeneOntologyBiologicalProcesscardiac cell development

NRAP MTOR OBSL1 NEB

6.71e-04132624GO:0055006
GeneOntologyBiologicalProcesspositive regulation of fatty acid beta-oxidation

ABCD1 ABCD2

6.79e-0413622GO:0032000
GeneOntologyBiologicalProcessneuron projection maintenance

ABCD1 ABCD2

6.79e-0413622GO:1990535
GeneOntologyBiologicalProcessregulation of fatty acid metabolic process

MTOR DBI ABCD1 ABCD2

7.10e-04134624GO:0019217
GeneOntologyBiologicalProcesspositive regulation of actin filament polymerization

MTOR CTTN HCK

7.46e-0459623GO:0030838
GeneOntologyBiologicalProcessresponse to decreased oxygen levels

MTOR KCNMA1 PRMT2 PYGM PCK1 DNMT3A

7.75e-04364626GO:0036293
GeneOntologyBiologicalProcesshypotonic response

PCK1 SLC12A5

7.90e-0414622GO:0006971
GeneOntologyBiologicalProcessactin filament organization

MICAL1 NRAP MTOR SPTB NEB CTTN HCK

8.14e-04509627GO:0007015
GeneOntologyBiologicalProcessregulation of Ras protein signal transduction

RASA4 RASA4B RASAL1

8.22e-0461623GO:0046578
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

MTOR DBI ABCD1 ABCD2 PCK1

8.62e-04246625GO:0046890
GeneOntologyBiologicalProcessregulation of establishment of planar polarity involved in neural tube closure

FZD1 FZD2

9.10e-0415622GO:0090178
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

MTOR SPTB LRP1 NEB CTTN HCK

1.02e-03384626GO:0032956
GeneOntologyBiologicalProcessestablishment of planar polarity involved in neural tube closure

FZD1 FZD2

1.04e-0316622GO:0090177
GeneOntologyBiologicalProcessnegative regulation of small GTPase mediated signal transduction

RASA4 RASA4B RASAL1

1.08e-0367623GO:0051058
GeneOntologyBiologicalProcessregulation of unsaturated fatty acid biosynthetic process

ABCD1 ABCD2

1.17e-0317622GO:2001279
GeneOntologyBiologicalProcesscellular anatomical entity morphogenesis

NRAP CKAP5 OBSL1 NEB

1.25e-03156624GO:0032989
GeneOntologyBiologicalProcessregulation of actin filament polymerization

MTOR SPTB CTTN HCK

1.25e-03156624GO:0030833
GeneOntologyBiologicalProcesscellular component assembly involved in morphogenesis

NRAP CKAP5 OBSL1 NEB

1.25e-03156624GO:0010927
GeneOntologyBiologicalProcessestablishment of planar polarity of embryonic epithelium

FZD1 FZD2

1.32e-0318622GO:0042249
GeneOntologyBiologicalProcessmyelin maintenance

ABCD1 ABCD2

1.32e-0318622GO:0043217
GeneOntologyBiologicalProcessresponse to calcium ion

RASA4 KCNMA1 RASA4B RASAL1

1.40e-03161624GO:0051592
GeneOntologyBiologicalProcesslong-chain fatty acid transport

ABCD3 ABCD1 ABCD2

1.44e-0374623GO:0015909
GeneOntologyBiologicalProcessregulation of establishment of planar polarity

FZD1 FZD2

1.47e-0319622GO:0090175
GeneOntologyBiologicalProcessneuron apoptotic process

FZD1 MTOR TRPC5 KCNMA1 LRP1 ARSG

1.48e-03413626GO:0051402
GeneOntologyBiologicalProcesslipid localization

TRPC5 ABCD3 LRP1 RNF213 DBI ABCD1 ABCD2

1.49e-03565627GO:0010876
GeneOntologyBiologicalProcessketone metabolic process

MTOR KCNMA1 DBI ABCD1 ABCD2

1.51e-03279625GO:0042180
GeneOntologyBiologicalProcessresponse to metal ion

CYP2R1 RASA4 KCNMA1 RASA4B RASAL1 DNMT3A

1.52e-03415626GO:0010038
GeneOntologyBiologicalProcessactin filament-based process

MICAL1 NRAP MTOR SPTB OBSL1 LRP1 NEB CTTN HCK

1.53e-03912629GO:0030029
GeneOntologyBiologicalProcesssmall molecule catabolic process

MTOR ABCD3 DBI ABCD1 ABCD2 PCK1

1.64e-03421626GO:0044282
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

MTOR SPTB CKAP5 LRP1 NEB CTTN HCK

1.71e-03579627GO:0051493
GeneOntologyBiologicalProcessresponse to oxygen levels

MTOR KCNMA1 PRMT2 PYGM PCK1 DNMT3A

1.82e-03430626GO:0070482
GeneOntologyBiologicalProcessheart development

FZD1 FZD7 NRAP MTOR OBSL1 LRP1 NEB FZD2

1.86e-03757628GO:0007507
GeneOntologyBiologicalProcesspositive regulation of fatty acid oxidation

ABCD1 ABCD2

1.98e-0322622GO:0046321
GeneOntologyBiologicalProcesslocomotor rhythm

MTOR KCNMA1

1.98e-0322622GO:0045475
GeneOntologyBiologicalProcessregulation of actin polymerization or depolymerization

MTOR SPTB CTTN HCK

1.98e-03177624GO:0008064
GeneOntologyBiologicalProcessregulation of actin filament-based process

MTOR SPTB LRP1 NEB CTTN HCK

2.00e-03438626GO:0032970
Domain-

RASA4 RASA4B RASAL1

3.31e-0836134.10.1130.10
DomainFrizzled

FZD1 FZD7 FZD8 FZD2

3.34e-0811614IPR000539
DomainFrizzled

FZD1 FZD7 FZD8 FZD2

3.34e-0811614PF01534
DomainFrizzled

FZD1 FZD7 FZD8 FZD2

3.34e-0811614SM01330
DomainABC_membrane_2

ABCD3 ABCD1 ABCD2

1.32e-074613PF06472
DomainFrizzled/SFRP

FZD1 FZD7 FZD8 FZD2

1.82e-0716614IPR015526
DomainFRI

FZD1 FZD7 FZD8 FZD2

4.80e-0720614SM00063
Domain-

FZD1 FZD7 FZD8 FZD2

5.91e-07216141.10.2000.10
DomainFrizzled_dom

FZD1 FZD7 FZD8 FZD2

1.04e-0624614IPR020067
DomainFZ

FZD1 FZD7 FZD8 FZD2

1.04e-0624614PS50038
DomainFz

FZD1 FZD7 FZD8 FZD2

1.04e-0624614PF01392
DomainBTK

RASA4 RASA4B RASAL1

2.75e-069613SM00107
DomainZnf_Btk_motif

RASA4 RASA4B RASAL1

2.75e-069613IPR001562
DomainBTK

RASA4 RASA4B RASAL1

2.75e-069613PF00779
DomainZF_BTK

RASA4 RASA4B RASAL1

2.75e-069613PS51113
DomainFA_transporter

ABCD3 ABCD1

1.05e-052612IPR005283
DomainRasGAP

RASA4 RASA4B RASAL1

1.18e-0514613SM00323
DomainRasGAP_CS

RASA4 RASA4B RASAL1

1.18e-0514613IPR023152
DomainRasGAP

RASA4 RASA4B RASAL1

1.47e-0515613PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B RASAL1

1.47e-0515613PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B RASAL1

1.47e-0515613PS50018
Domain-

RASA4 RASA4B RASAL1

1.80e-05166131.10.506.10
DomainRasGAP_dom

RASA4 RASA4B RASAL1

2.61e-0518613IPR001936
DomainGPCR_2_secretin-like

FZD1 FZD7 FZD8 FZD2

4.38e-0560614IPR000832
DomainGPCR_2-like

FZD1 FZD7 FZD8 FZD2

4.38e-0560614IPR017981
DomainG_PROTEIN_RECEP_F2_4

FZD1 FZD7 FZD8 FZD2

4.68e-0561614PS50261
DomainNEBU

NRAP NEB

6.27e-054612SM00227
DomainNebulin

NRAP NEB

6.27e-054612PF00880
DomainNebulin

NRAP NEB

6.27e-054612IPR013998
DomainNEBULIN

NRAP NEB

6.27e-054612PS51216
DomainNebulin_repeat

NRAP NEB

6.27e-054612IPR000900
DomainABC_TM1F

ABCD3 ABCD1 ABCD2

1.02e-0428613PS50929
DomainABC1_TM_dom

ABCD3 ABCD1 ABCD2

1.02e-0428613IPR011527
DomainAAA+_ATPase

DNAH12 ABCD3 RNF213 ABCD1 ABCD2

1.07e-04144615IPR003593
DomainAAA

DNAH12 ABCD3 RNF213 ABCD1 ABCD2

1.07e-04144615SM00382
DomainABC_transporter_CS

ABCD3 ABCD1 ABCD2

3.48e-0442613IPR017871
DomainABC_tran

ABCD3 ABCD1 ABCD2

5.16e-0448613PF00005
DomainABC_TRANSPORTER_2

ABCD3 ABCD1 ABCD2

5.16e-0448613PS50893
DomainABC_TRANSPORTER_1

ABCD3 ABCD1 ABCD2

5.49e-0449613PS00211
DomainABC_transporter-like

ABCD3 ABCD1 ABCD2

5.82e-0450613IPR003439
DomainC2

CADPS RASA4 RASA4B RASAL1

8.85e-04131614PF00168
DomainPH

CADPS RASA4 RASA4B CNKSR2 RASAL1

9.03e-04229615PF00169
DomainLdl_recept_b

LRP1 SORL1

9.31e-0414612PF00058
DomainLDLRB

LRP1 SORL1

9.31e-0414612PS51120
DomainC2

CADPS RASA4 RASA4B RASAL1

1.05e-03137614SM00239
DomainLY

LRP1 SORL1

1.07e-0315612SM00135
DomainLDLR_classB_rpt

LRP1 SORL1

1.07e-0315612IPR000033
DomainC2

CADPS RASA4 RASA4B RASAL1

1.19e-03142614PS50004
DomainC2_dom

CADPS RASA4 RASA4B RASAL1

2.03e-03164614IPR000008
DomainSH3_1

PRMT2 NEB CTTN HCK

2.03e-03164614PF00018
DomainSH3_9

PRMT2 NEB CTTN

2.12e-0378613PF14604
DomainPH

CADPS RASA4 RASA4B CNKSR2 RASAL1

2.12e-03278615SM00233
DomainPH_DOMAIN

CADPS RASA4 RASA4B CNKSR2 RASAL1

2.16e-03279615PS50003
DomainPH_domain

CADPS RASA4 RASA4B CNKSR2 RASAL1

2.19e-03280615IPR001849
DomainRho_GTPase_activation_prot

RASA4 RASA4B RASAL1

2.99e-0388613IPR008936
DomainSH3

PRMT2 NEB CTTN HCK

5.43e-03216614SM00326
DomainSH3

PRMT2 NEB CTTN HCK

5.43e-03216614PS50002
DomainSH3_domain

PRMT2 NEB CTTN HCK

5.79e-03220614IPR001452
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD1 FZD7 FZD8 FZD2

1.37e-0714504M47834
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 FZD2

2.47e-0716504M47823
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

FZD1 FZD7 FZD8 LRP1

3.22e-0717504M39525
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD1 FZD7 FZD8 FZD2

5.22e-0719504M47833
PathwayPID_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 FZD2

2.69e-0628504M77
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD7 FZD8 FZD2

7.59e-0636504M39699
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD1 FZD7 FZD8 MTOR FZD2

1.21e-0585505M48315
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD7 FZD8 FZD2

1.71e-0544504MM15878
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 FZD2

1.87e-0545504M47412
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

FZD1 FZD7 FZD8 RAMP1 FZD2

1.98e-0594505M797
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 FZD2

2.05e-0546504M47409
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCD3 ABCD1 ABCD2

2.76e-0517503MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCD3 ABCD1 ABCD2

3.30e-0518503M524
PathwayREACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT

ABCD3 ABCD1 ABCD2

3.91e-0519503MM15651
PathwayKEGG_BASAL_CELL_CARCINOMA

FZD1 FZD7 FZD8 FZD2

4.18e-0555504M17807
PathwayWP_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 LRP1 FZD2

4.23e-05110505MM15977
PathwayREACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT

ABCD3 ABCD1 ABCD2

4.59e-0520503M27930
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

FZD1 FZD7 FZD8 MTOR FZD2

5.45e-05116505MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

FZD1 FZD7 FZD8 MTOR FZD2

5.68e-05117505M39530
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD7 FZD8 FZD2

5.90e-0560504MM15150
PathwayWP_WNT_SIGNALING

FZD1 FZD7 FZD8 FZD2

6.30e-0561504MM15893
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD7 FZD8 FZD2

7.61e-0564504M27396
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

FZD1 FZD7 FZD8 FZD2

8.58e-0566504M39642
PathwayWP_BREAST_CANCER_PATHWAY

FZD1 FZD7 FZD8 MTOR FZD2

2.08e-04154505M39739
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD7 FZD8 FZD2

2.29e-0485504MM15041
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

FZD1 FZD7 FZD8 FZD2

2.74e-0489504M39563
PathwayWNT_SIGNALING

FZD1 FZD7 FZD8 FZD2

2.74e-0489504M5493
PathwayWP_ALZHEIMERS_DISEASE

FZD1 FZD7 FZD8 MTOR LRP1 FZD2

3.05e-04261506M42565
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD7 FZD8 FZD2

3.11e-0492504M27322
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP

RASA4 RASAL1

3.41e-048502M47935
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

ABCD3 LRP1 DBI ABCD1 CTTN ABCD2 SORL1

3.66e-04381507M48063
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 FZD7 FZD8 FZD2

3.96e-0498504M39731
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

FZD1 FZD7 FZD8 FZD2

4.44e-04101504M39387
PathwayKEGG_MELANOGENESIS

FZD1 FZD7 FZD8 FZD2

4.44e-04101504M7761
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

FZD1 FZD7 FZD8 FZD2

4.44e-04101504MM15829
PathwayKEGG_ABC_TRANSPORTERS

ABCD3 ABCD1 ABCD2

5.02e-0444503M11911
PathwayWP_WNT_SIGNALING_WP428

FZD1 FZD7 FZD8 FZD2

6.79e-04113504M39669
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 FZD7 FZD8 FZD2

7.98e-04118504M39852
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD7 FZD8 FZD2

9.32e-04123504MM14988
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

FZD1 FZD7 FZD8 MTOR LRP1 FZD2

9.85e-04326506M39379
PathwayREACTOME_REGULATION_OF_RAS_BY_GAPS

RASA4 RASA4B RASAL1

1.64e-0366503MM15261
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD7 FZD8 FZD2

1.76e-03146504M27288
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD8 FZD2

1.99e-03151504M19428
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

FZD1 FZD7 FZD8 FZD2

2.51e-03161504M39770
PathwayKEGG_PEROXISOME

ABCD3 ABCD1 ABCD2

2.65e-0378503M6391
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD1 FZD7 FZD8 FZD2

2.04e-091063415245425
Pubmed

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

FZD1 FZD7 FZD8 FZD2

2.04e-091063417532316
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD1 FZD7 FZD8 FZD2

3.19e-091163424860427
Pubmed

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

FZD1 FZD7 FZD8 FZD2

3.19e-091163430978219
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD1 FZD7 FZD8 FZD2

3.19e-091163417582687
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD1 FZD7 FZD8 FZD2

3.19e-091163417576136
Pubmed

Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7.

FZD1 FZD7 FZD2

5.66e-0936339813155
Pubmed

Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters.

ABCD3 ABCD1 ABCD2

5.66e-09363310551832
Pubmed

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

FZD1 FZD7 FZD2

5.66e-09363327680706
Pubmed

Peroxisomal ABC Transporters: An Update.

ABCD3 ABCD1 ABCD2

5.66e-09363334198763
Pubmed

Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3).

ABCD3 ABCD1 ABCD2

5.66e-09363317609205
Pubmed

Characterization of human ATP-binding cassette protein subfamily D reconstituted into proteoliposomes.

ABCD3 ABCD1 ABCD2

5.66e-09363329397936
Pubmed

Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p.

ABCD3 ABCD1 ABCD2

2.26e-08463310777694
Pubmed

Identification of novel SNPs of ABCD1, ABCD2, ABCD3, and ABCD4 genes in patients with X-linked adrenoleukodystrophy (ALD) based on comprehensive resequencing and association studies with ALD phenotypes.

ABCD3 ABCD1 ABCD2

2.26e-08463320661612
Pubmed

ABC Transporter Subfamily D: Distinct Differences in Behavior between ABCD1-3 and ABCD4 in Subcellular Localization, Function, and Human Disease.

ABCD3 ABCD1 ABCD2

2.26e-08463327766264
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD1 FZD7 FZD8 FZD2

2.29e-081763428733458
Pubmed

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.

FZD1 FZD7 FZD8 FZD2

3.71e-081963421623369
Pubmed

Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly.

ABCD3 ABCD1 ABCD2

5.65e-08563311883941
Pubmed

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

FZD1 FZD7 FZD8 FZD2

6.98e-082263417064353
Pubmed

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways.

FZD1 FZD7 FZD2

1.13e-07663336867021
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD1 FZD7 FZD8 FZD2

1.20e-072563412812787
Pubmed

The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression.

ABCD3 ABCD1 ABCD2

1.97e-07763310504404
Pubmed

Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

FZD1 FZD7 FZD8

1.97e-07763315370539
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

FZD1 FZD7 FZD8 FZD2

2.24e-072963418364260
Pubmed

Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis.

FZD1 FZD7 FZD8

3.15e-07863310559494
Pubmed

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.

FZD1 FZD7 FZD2

3.15e-07863319388021
Pubmed

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.

FZD1 FZD7 FZD2

4.72e-07963323095888
Pubmed

Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.

FZD1 FZD7 FZD2

4.72e-07963312067714
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD1 FZD7 FZD2

4.72e-0796339707618
Pubmed

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

FZD1 FZD7 FZD8 FZD2

5.51e-073663424151333
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

FZD1 FZD7 FZD8 FZD2

6.17e-073763415342465
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

FZD1 FZD7 FZD8 FZD2

6.17e-073763418800919
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

FZD1 FZD7 FZD8 FZD2

6.89e-073863421041481
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

FZD1 FZD7 FZD8 FZD2

6.89e-073863418635608
Pubmed

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.

FZD1 FZD7 FZD2

1.60e-061363321246654
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

FZD1 FZD7 FZD8 FZD2

1.64e-064763428813421
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

FZD1 FZD7 FZD8 FZD2

1.64e-064763418351675
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

FZD1 FZD7 FZD8 FZD2

1.64e-064763433141892
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

FZD1 FZD7 FZD8 FZD2

1.95e-064963419562671
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

FZD1 FZD7 FZD8 FZD2

2.11e-065063427510977
Pubmed

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.

FZD7 FZD8 FZD2

2.54e-061563315617677
Pubmed

Interspecific backcross mice show sex-specific differences in allelic inheritance.

NEB HCK PCK1

2.54e-06156331916246
Pubmed

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

ABCD3 ABCD1 ABCD2

3.12e-061663310704444
Pubmed

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.

ABCD1 ABCD2

3.23e-06263218854420
Pubmed

Peroxisomal ATP-binding cassette transporters form mainly tetramers.

ABCD1 ABCD2

3.23e-06263228258215
Pubmed

Chromosomal localization of the adrenoleukodystrophy-related gene in man and mice.

ABCD3 ABCD2

3.23e-0626329195160
Pubmed

Distinct phosphoinositide binding specificity of the GAP1 family proteins: characterization of the pleckstrin homology domains of MRASAL and KIAA0538.

RASA4 RASAL1

3.23e-06263211594756
Pubmed

Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers.

ABCD1 ABCD2

3.23e-06263225043761
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

3.23e-06263211448776
Pubmed

Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters.

ABCD3 ABCD1

3.23e-06263211248239
Pubmed

Mouse liver PMP70 and ALDP: homomeric interactions prevail in vivo.

ABCD3 ABCD1

3.23e-06263215276650
Pubmed

Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation.

ABCD1 ABCD2

3.23e-06263221145416
Pubmed

The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage.

ABCD1 ABCD2

3.23e-06263217260006
Pubmed

Effect of testosterone metabolites on ABC half-transporter relative gene expression in X-linked adrenoleukodystrophy.

ABCD3 ABCD2

3.23e-06263217602313
Pubmed

Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.

ABCD1 ABCD2

3.23e-06263218723473
Pubmed

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.

ABCD1 ABCD2

3.23e-06263220179078
Pubmed

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy.

ABCD1 ABCD2

3.23e-06263230769094
Pubmed

Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism.

ABCD3 ABCD1

3.23e-0626329126326
Pubmed

Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts.

FZD1 FZD2

3.23e-06263220189955
Pubmed

Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked Adrenoleukodystrophy.

ABCD1 ABCD2

3.23e-06263236207570
Pubmed

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.

ABCD1 ABCD2

3.23e-06263225255441
Pubmed

ATP-binding and -hydrolysis activities of ALDP (ABCD1) and ALDRP (ABCD2), human peroxisomal ABC proteins, overexpressed in Sf21 cells.

ABCD1 ABCD2

3.23e-06263216946495
Pubmed

Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins.

ABCD3 ABCD1

3.23e-0626329425230
Pubmed

Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations.

ABCD3 ABCD1

3.23e-06263217542813
Pubmed

Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy.

ABCD1 ABCD2

3.23e-06263215489218
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

3.23e-06263216041389
Pubmed

Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.

ABCD1 ABCD2

3.23e-06263210196381
Pubmed

Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.

FZD1 FZD7 FZD8

3.78e-061763326443994
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CADPS KHNYN CKAP5 OBSL1 GON4L CNKSR2 SLC12A5

8.99e-0640763712693553
Pubmed

Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.

ABCD1 ABCD2

9.68e-06363225822341
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

9.68e-06363225637021
Pubmed

CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.

RASA4 RASAL1

9.68e-06363216009725
Pubmed

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.

LRP1 SORL1

9.68e-06363228799085
Pubmed

Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.

FZD1 FZD7

9.68e-06363235296808
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD7 FZD8 FZD2

1.12e-05246339096311
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD7 FZD8 FZD2

1.12e-05246338626800
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

ABCD3 ABCD1 ABCD2

1.27e-052563335681537
Pubmed

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

NEB CTTN HCK

1.80e-052863318067320
Pubmed

A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin.

KCNMA1 CTTN

1.93e-05463217065230
Pubmed

Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.

FZD1 FZD8

1.93e-05463222303445
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

1.93e-05463221460216
Pubmed

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2.

FZD7 FZD2

1.93e-05463218215320
Pubmed

Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle.

FZD7 MTOR

1.93e-05463222179044
Pubmed

TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway.

MTOR TRPC5

1.93e-05463228600513
Pubmed

The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway.

FZD1 LRP1

1.93e-05463214739301
Pubmed

Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.

FZD1 FZD2

1.93e-05463218929644
Pubmed

Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.

ABCD1 ABCD2

1.93e-05463229997171
Pubmed

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.

RASA4 RASA4B

1.93e-05463216234249
Pubmed

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

LRP1 SORL1

1.93e-05463223283348
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD1 FZD7 FZD8 FZD2

2.22e-059063419515997
Pubmed

Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.

FZD1 FZD7

3.22e-05563219543507
Pubmed

Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family.

LRP1 SORL1

3.22e-05563217326667
Pubmed

Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor.

MTOR LRP1

3.22e-05563221454706
Pubmed

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling.

FZD7 FZD8

3.22e-05563218256285
Pubmed

Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation.

RPS6KA5 MTOR

3.22e-05563211777913
Pubmed

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner.

FZD7 FZD8

3.22e-05563210395542
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 SORL1

3.22e-05563219047013
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

FZD7 FZD8 FZD2

3.88e-053663312412008
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

FZD1 FZD7 FZD8

4.21e-053763335831952
Pubmed

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling.

FZD7 FZD2

4.82e-05663220802536
InteractionSCGB1C1 interactions

FZD1 FZD7 FZD2

7.76e-0613623int:SCGB1C1
InteractionABCD2 interactions

ABCD3 ABCD1 ABCD2

2.19e-0518623int:ABCD2
Cytoband3p14.3

DNAH12 SPATA12

7.86e-04306323p14.3
CytobandEnsembl 112 genes in cytogenetic band chr3p14

DNAH12 SPATA12 CADPS

9.64e-04140633chr3p14
Cytoband11p11.2

FNBP4 CKAP5

5.87e-038363211p11.2
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 FZD7 FZD8 FZD2

2.31e-0811544286
GeneFamilyATP binding cassette subfamily D

ABCD3 ABCD1 ABCD2

1.01e-074543808
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B RASAL1

2.98e-0610543830
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

CADPS SPTB RASA4B CNKSR2 RASAL1

3.68e-04206545682
CoexpressionGSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP

RAMP1 RASA4 FNBP4 SOWAHC HCK REV1

8.42e-06199636M7483
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

FZD8 CD207 FNBP4 ABCD3 PYGM DNMT3A

8.66e-06200636M9188
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

FZD1 FZD7 FZD8 RAMP1 FZD2

1.86e-05135635M5825
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FZD1 FZD7 RPS6KA5 SPATA12 CADPS ARSG

1.06e-071606368a4746463ca1976f7d6de803496c851249ced797
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 RASA4 LRP1 SOWAHC HCK

4.53e-061726355f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MICAL1 KCNMA1 LRP1 RNF213 HCK

4.79e-06174635d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADPS RASA4 SPTB RASA4B SLC12A5

5.20e-06177635c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAMP1 NRAP CADPS SPTB ABCD3

6.12e-061836352902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCelltumor_Lung-Myeloid_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

CD207 KCNMA1 DBI HCK SLC12A5

6.12e-061836357ef79365514e62dfc2e182e873e2b413d4f46b46
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 RASA4 KCNMA1 GALNT7

6.12e-06183635ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 RASA4 KCNMA1 GALNT7

6.12e-06183635c52b84034503d931f7b87312d2ff86daff14152d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADPS RASA4 TRPC5 KCNMA1 SLC12A5

6.97e-061886351efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SULT1C2 SPATA12 KCNMA1 HCK SLC12A5

6.97e-06188635fcf1bebef7aa81b4a11c1f9e4319339c290ecd22
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

RAMP1 NRAP CADPS SPTB ABCD3

7.34e-061906353729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 RASA4 KCNMA1 GALNT7 PCK1

7.92e-061936356a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 KCNMA1 GALNT7 PCK1

7.92e-061936354aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 KCNMA1 GALNT7 PCK1

7.92e-06193635aaa5042388dc451bff384c6bb237348f08280a08
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAMP1 NRAP SPTB PYGM NEB

8.75e-0619763544e49943d62bfe622b40ad0460093d31540544df
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

SPTB KCNMA1 NEB FBXO27 HCK

8.75e-0619763515b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

SPTB KCNMA1 NEB FBXO27 HCK

8.75e-06197635a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellmLN-Macrophage-Macrophage|mLN / Region, Cell class and subclass

SPATA12 KCNMA1 OBSL1 HCK SLC12A5

9.19e-061996356bbec8450afb30347b07da28401a698fc51a3c53
ToppCellmLN-(6)_Macrophage-(60)_Macrophage|mLN / shred on region, Cell_type, and subtype

SPATA12 KCNMA1 OBSL1 HCK SLC12A5

9.19e-061996351ea28b832c6173b1b58da432aaf21e6cd291561e
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

AACS ARMCX4 ABCD2 SLC12A5

4.64e-05140634407691970ec72a3afb45e431cf48814546b8acff
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

RAMP1 KHNYN TRPC5 KCNMA1

4.64e-051406345623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TRPC5 CNKSR2 RASAL1 SORL1

5.04e-051436345fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

AACS ARMCX4 ABCD2 SLC12A5

5.32e-0514563445e8089fdf7d6f69b383816d8945e39fba24c873
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-Langerhans_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RAMP1 CD207 FBXO27 RASAL1

6.72e-05154634617ad0929d2ac0eeb7b8d9b0cba687176e684ed0
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

RPS6KA5 PYGM ABCD2 REV1

6.72e-05154634c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP1 AACS LRP1 ARSG

8.18e-05162634d712bc31840ad1523e3dbf884acbb428a8995001
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 SOWAHC HCK

8.57e-05164634cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 SOWAHC HCK

8.57e-0516463412251a49fd4af32d4edb58046245548c260cf04b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM132C RAMP1 MAGED4 GALNT7

9.41e-05168634e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM132C RAMP1 MAGED4 GALNT7

9.41e-05168634b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCellfacs-BAT-Fat-18m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 LRP1 SOWAHC HCK

1.03e-0417263436fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP PYGM NEB PCK1

1.08e-041746344a6e04b4f12b87c15fa1409989cbe32c43736369
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

WDR38 NLRP9 DNAH12 PYGM

1.13e-041766348e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 RASA4 GALNT7

1.18e-0417863407d6d5275a4d17f8024fde74e92ab2505b4adfbf
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 DBI HCK

1.20e-0417963466afd54428e6dcadc3e341faecfde42be4fb5905
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 CD207 PYGM DBI

1.20e-041796347ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 DBI HCK

1.20e-04179634fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 DBI HCK

1.20e-041796346d2458a887047b5c20389f08345ff5aac7c683e6
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

NRAP SULT1C2 KCNMA1 LRP1

1.20e-04179634b4430f633711cecf793e8e76e766a66ff1eff473
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

TMEM132C AACS ABCD2 PCK1

1.23e-04180634d48a3d27357f7d184132a6805950f93080146b59
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C RAMP1 LRP1 CNKSR2

1.23e-041806349b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C RAMP1 LRP1 CNKSR2

1.25e-041816349e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCelldroplet-Lung-30m-Hematologic-myeloid|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAMP1 LRP1 DBI HCK

1.25e-0418163475751d390812c98cc2b32ab578cdb15b34a80750
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

SULT1C2 KCNMA1 PYGM SORL1

1.25e-041816344a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

TMEM132C RAMP1 PYGM SLC12A5

1.25e-04181634f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP1 CADPS CNKSR2 SLC12A5

1.25e-041816347f99002a6411117cc2361334c7c9228e20c574b4
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MICAL1 LRP1 RNF213 NEB

1.28e-041826344234d0cc57b5266a5e03133c75c7918abe48465e
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

TMEM132C AACS ABCD2 PCK1

1.31e-04183634b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

TMEM132C AACS ABCD2 PCK1

1.31e-041836343f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 RASA4 KCNMA1 ARSG

1.31e-041836345a936fb07074cec753bf19e3e3e52499605ea22c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 RASA4 KCNMA1 ARSG

1.31e-0418363407c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAMP1 NRAP CADPS SPTB

1.34e-04184634e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAMP1 NRAP CADPS SPTB

1.36e-04185634549eeb521c3985bff396ea0f202db21822efa51f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAMP1 KCNMA1 CNKSR2 RASAL1

1.39e-0418663456c139e679d640ea901ead657a8e8887e0fca098
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

KCNMA1 LRP1 FZD2 HCK

1.39e-04186634a16ecf70271894a842925f232009e2623d16947e
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP1 SULT1C2 CTTN RASAL1

1.39e-041866346d8dd6d0403d149cb6edb346581fe6c248036785
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 RASA4 KCNMA1 GALNT7

1.39e-0418663432d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PRMT2 ABCD2 DNMT3A SORL1

1.45e-04188634b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RAMP1 CD207 FBXO27 HCK

1.45e-0418863478e79b8e298aa77c8c01320bab4fb1a00f11a772
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

FZD1 LRP1 FZD2 HCK

1.45e-04188634d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

FZD1 LRP1 FZD2 HCK

1.45e-041886340bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDR38 SPATA12 HCK SLC12A5

1.45e-04188634f955f2eb92f399958d4d713e31af77d93fb4a6ec
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

TMEM132C AACS ABCD2 PCK1

1.45e-041886344dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell21-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

CADPS KCNMA1 PYGM NEB

1.45e-04188634e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 SULT1C2 GALNT7 PCK1

1.48e-04189634e11998c57609c5714705713ac3a32016d6d841dd
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C RAMP1 KCNMA1 LRP1

1.48e-0418963445e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-migDC|GI_small-bowel / Manually curated celltypes from each tissue

CD207 DBI FBXO27 HCK

1.51e-04190634e9b2c201d07f0cb87fa60005251c9e1663e246ed
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C RAMP1 KCNMA1 LRP1

1.54e-0419163414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP1 PYGM ABCD2 FZD2

1.54e-04191634fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FZD1 TMEM132C FZD7 CADPS

1.57e-0419263472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

WDR38 DNAH12 RAMP1 ANKUB1

1.60e-041936343e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCelldistal-Hematologic-Basophil/Mast_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPS6KA5 CADPS SPTB FBXO27

1.60e-04193634f22d0a2ea6bbdd625909ccb6a89aca89ab670306
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 RAMP1 FZD2

1.60e-04193634eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCelldistal-Hematologic-Basophil/Mast_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPS6KA5 CADPS SPTB FBXO27

1.60e-04193634dcdc1498726c68bf590bf84cb81e5f7fb7ba4d78
ToppCelldistal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPS6KA5 CADPS SPTB FBXO27

1.60e-0419363423c6c798525dad43eff792727902ea562bf373be
ToppCell3'_v3-bone_marrow-Lymphocytic_NK|bone_marrow / Manually curated celltypes from each tissue

RAMP1 RNF213 PRMT2 DBI

1.60e-04193634e790ab76c12f74a13936c231076f1e397283efb3
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RPS6KA5 CADPS DBI ARSG

1.64e-04194634d8f367beab16a3186821e42311947b6c9e99978c
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 KCNMA1 GALNT7

1.64e-041946340797245ebfa389a6f66874cb0f11297f1456e600
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAMP1 CD207 FBXO27 RASAL1

1.64e-04194634f0467d81063a9b19783906c456935ef8318b9b98
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 RAMP1 FZD2

1.64e-041946345d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCelldistal-1-Hematologic-Myeloid_Dendritic_Type_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAMP1 CD207 FBXO27 RASAL1

1.64e-0419463485a4be291c25ad1fb14199b87d822cf47d748fc0
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 RAMP1 KCNMA1 GALNT7

1.64e-041946340241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

RASA4 ABCD3 EIF3K DBI

1.67e-041956346d6c1197d6fd56f628ec9d22723abcb9700306f7
ToppCellHealthy_Control-Myeloid-mDC|Healthy_Control / Condition, Lineage, Cell class and cell subclass

RAMP1 CD207 FZD2 RASAL1

1.67e-0419563432f505b2c24f4386367706b775e79271f99156f2
ToppCellmetastatic_Brain-Myeloid_cells-Microglia/Mac|metastatic_Brain / Location, Cell class and cell subclass

KCNMA1 LRP1 DBI HCK

1.67e-04195634ae48d493ebda5f87781181a3d1d73d8f84fc5e77
ToppCellHealthy_Control-Myeloid-mDC-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

RAMP1 CD207 FZD2 RASAL1

1.67e-04195634d9a6fc7fa0047472821e1dcf0962ccb3f061313e
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FNBP4 PRMT2 DNMT3A SORL1

1.67e-04195634d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

WDR38 DNAH12 RAMP1 ANKUB1

1.70e-041966349a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RPS6KA5 CADPS DBI ARSG

1.70e-0419663403710e2a843279124a45a271bffb132835e6081c
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CKAP5 CNKSR2 NEB RASAL1

1.74e-04197634ff4df77117165b6b25315e29b0722cc136eba607
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

WDR38 DNAH12 RAMP1 ANKUB1

1.74e-0419763462e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RPS6KA5 CADPS DBI ARSG

1.74e-041976345e4a004052b8560223673a339d4a0d729e533def
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SULT1C2 KCNMA1 FZD2 HCK

1.74e-04197634780ab4a9f1dbf1f58b70a716ba2949c4f51b9295
ToppCellnormal_Lymph_Node-Myeloid_cells-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

KCNMA1 LRP1 DBI HCK

1.74e-04197634d8dc65b580191827ab6bbad5e29f0089419ebaef
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_2|COVID-19_Mild / Disease condition and Cell class

LRP1 CTTN HCK SORL1

1.74e-04197634e844f660010d114d65bd814f3d3fccd8e4a6b8da
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAMP1 CD207 FBXO27 RASAL1

1.74e-0419763481dd7f9318f0ba175352e5156c24772427e0b34f
ToppCell343B-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RAMP1 GON4L RNF213 ARSG

1.74e-04197634879974aff3f887648a00b4659b46d9897c9eb467
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

ANKUB1 KCNMA1 LRP1 HCK

1.77e-0419863433f0a919188a67d2a876b52c61a1cec2c9747969
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CADPS KCNMA1 CNKSR2 SLC12A5

1.77e-04198634c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CADPS KCNMA1 CNKSR2 SLC12A5

1.77e-041986346d18b45eda4014759e6dd282d78ffd28df8a6044
ComputationalGenes in the cancer module 99.

FZD1 FZD7 RAMP1 SULT1C2 ABCD1 PCK1 ARSG

1.27e-04357357MODULE_99
Diseaseadrenoleukodystrophy (implicated_via_orthology)

ABCD3 ABCD1 ABCD2

2.78e-077603DOID:10588 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ABCD3 LRP1 ZNF624 HTR3C CNKSR2 ABCD2 SLC12A5 SORL1

8.48e-05702608C0009402
Diseaseglypican-1 measurement

B4GALT7 NRAP

8.48e-057602EFO_0801649
DiseaseAlzheimer's disease (is_implicated_in)

KCNMA1 LRP1 PCK1 SORL1

1.54e-04132604DOID:10652 (is_implicated_in)
DiseaseMetabolic Bone Disorder

CYP2R1 KCNMA1

3.64e-0414602C0005944
Diseaselobe size

SULT1C2 SOWAHC

3.64e-0414602EFO_0007666
DiseaseOsteopenia

CYP2R1 KCNMA1

4.20e-0415602C0029453
Diseasefat intake measurement

NRAP DNMT3A

9.15e-0422602EFO_0010809
DiseaseOvarian Mucinous Adenocarcinoma

MTOR HCK

1.82e-0331602C1335167

Protein segments in the cluster

PeptideGeneStartEntry
DAWLKEDGVIWPTMA

PRMT2

231

P55345
AAEGTRWVMWFGDGK

DNMT3A

321

Q9Y6K1
EGGWDAVMDWKDVLS

ABCD2

596

Q9UBJ2
MAVEAWNEEGKAVWG

AACS

466

Q86V21
GEWGLAAAGAWETMH

CLK3

136

P49761
DGGSGWTKTQLMELW

HTR3C

401

Q8WXA8
ILADDMGWGDLGANW

ARSG

41

Q96EG1
MGWGDLGANWAETKD

ARSG

46

Q96EG1
GMGSWDGAMIWSETK

ARMCX4

1986

Q5H9R4
WDWDMVGKNDFLGMV

RASAL1

201

O95294
GAMEALCVEAWDWDL

RASA4

191

O43374
VDMEAVGETLWCDWG

RAMP1

46

O60894
PGWKVECVGDDIAWM

PCK1

301

P35558
GAMEALCVEAWDWDL

RASA4B

191

C9J798
REGGWEAMCDWKDVL

ABCD1

591

P33897
WEKDGMALDEVWDSS

OBSL1

161

O75147
DKGEAFAWWSDLMVE

CADPS

906

Q9ULU8
MNIGDEALIGRWSWD

MAGED4

636

Q96JG8
AVAAEVGWMTSVKDW

KCNMA1

151

Q12791
DLAWMKGVGWLTEGS

NRAP

686

Q86VF7
PEAVQDWDSWFSMKG

MSS51

181

Q4VC12
ALAIMGDKLWWADQV

LRP1

1791

Q07954
GDKLWWADQVSEKMG

LRP1

1796

Q07954
GMSNRFWGWGREDDE

B4GALT7

216

Q9UBV7
TWFLAAGMKWGHEAI

FZD2

351

Q14332
WQRSEKRWMDGGFLD

DNAH12

696

Q6ZR08
AAWMVKRWAEGAESL

MICAL1

416

Q8TDZ2
GHDKAVDWWSLGVLM

RPS6KA5

231

O75582
TWFLAAGMKWGHEAI

FZD1

426

Q9UP38
WFLAAGMKWGHEAIE

FZD7

361

O75084
WFLAAGMKWGNEAIA

FZD8

421

Q9H461
NAWAEQTGMKEWLEG

CKAP5

966

Q14008
KGDQMVVLEESGEWW

HCK

101

P08631
MWKLWRAEEGAAALG

CYP2R1

1

Q6VVX0
GDEDGYARGAWDWSM

GALNT7

346

Q86SF2
NTADDEDWKMWLGGL

GON4L

526

Q3T8J9
EDWKMWLGGLMNDDV

GON4L

531

Q3T8J9
GMLDFTGKAKWDAWN

DBI

46

P07108
KVWMSKYGWSADESG

EIF3K

171

Q9UBQ5
REMDWGWKELPGEEA

KHNYN

266

O15037
KWMVQHGGDGWVVEE

FBXO27

126

Q8NI29
QSGEDWWYMGERCEK

MEP1B

631

Q16820
EGSIDVWWIVHDGGM

SLC12A5

846

Q9H2X9
AAAAAWGLGQWDSME

MTOR

1516

P42345
QEGVMFWTDWGDLKP

SORL1

886

Q92673
WVWLGNEAELLESMG

TMEM132C

971

Q8N3T6
AGVGIEMGDWQEVWD

FNBP4

211

Q8N3X1
WMLSASDGKWDSLEG

SOWAHC

271

Q53LP3
WDSVQDWMDVLSGGE

ABCD3

561

P28288
LDVWDGWKEFLMGCL

ANKUB1

156

A6NFN9
YWIGLTKAGMEGDWS

CD207

251

Q9UJ71
TKAGMEGDWSWVDDT

CD207

256

Q9UJ71
WSPSQVVDWMKGLDD

CNKSR2

11

Q8WXI2
MLDWAEGNLWKDRFT

NLRP9

166

Q7RTR0
HGWKESLLGDMEWRL

RNF213

951

Q63HN8
TENGLWDSRMEGLWK

ZNF624

156

Q9P2J8
ISGGWQMEEADDWLR

PYGM

171

P11217
GMEDGDNERTTGWLW

SPATA12

131

Q7Z6I5
ENDGWETWGGYMAAK

REV1

11

Q9UBZ9
NIEMIDDGWWRGVCK

CTTN

521

Q14247
EGMYADWWQEPDAKG

P3H4

411

Q92791
GSWFDHVKGWWEMKD

SULT1C2

171

O00338
SAGDGEVKAWLWAEM

THOC6

91

Q86W42
ATIAEWKDGLNEMWA

SPTB

1766

P11277
WKDGLNEMWADLLEL

SPTB

1771

P11277
ASGGWDKRVMLWDVQ

WDR38

121

Q5JTN6
VLGFIWGEIKEMWDG

TRPC5

411

Q9UL62
WLKGIGWMTSGSLED

NEB

2661

P20929