Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.17e-05281484GO:0001972
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.27e-04351484GO:0015020
GeneOntologyMolecularFunctionprotein kinase C binding

PRKD2 UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.30e-04661485GO:0005080
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

EP400 RSF1 CHD1 RAD54L2

1.58e-04371484GO:0140658
GeneOntologyMolecularFunctionmalate dehydrogenase (decarboxylating) (NADP+) activity

ME1 ME3

1.63e-0431482GO:0004473
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

TYW3 EP400 RSF1 CHD1 DDX51 PIWIL2 MSH4 DCLRE1B RAD54L2 EXOSC2 CNOT6L INTS11 DDX3Y CMTR2

3.21e-0464514814GO:0140640
GeneOntologyMolecularFunctionmalic enzyme activity

ME1 ME3

3.24e-0441482GO:0004470
GeneOntologyMolecularFunctionoxaloacetate decarboxylase activity

ME1 ME3

3.24e-0441482GO:0008948
GeneOntologyMolecularFunctionretinoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.38e-04481484GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.74e-04491484GO:0019840
GeneOntologyMolecularFunctionsteroid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 OSBPL1A NR3C2

4.74e-041331486GO:0005496
GeneOntologyMolecularFunctionthiol oxidase activity

ERO1A P4HB

8.03e-0461482GO:0016972
GeneOntologyMolecularFunctionO-methyltransferase activity

ASMTL PCMTD2 CMTR2

8.14e-04251483GO:0008171
GeneOntologyMolecularFunction7S RNA binding

SRP72 EXOSC2

1.12e-0371482GO:0008312
GeneOntologyMolecularFunctiontranslation termination factor activity

GSPT1 GSPT2

1.12e-0371482GO:0008079
GeneOntologyMolecularFunctiontranslation release factor activity

GSPT1 GSPT2

1.12e-0371482GO:0003747
GeneOntologyMolecularFunctionmalate dehydrogenase activity

ME1 ME3

1.48e-0381482GO:0016615
GeneOntologyMolecularFunctionfatty acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.72e-03691484GO:0005504
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.20e-0851464GO:0006711
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.57e-0861464GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.57e-0861464GO:0046226
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.57e-0861464GO:0051552
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-07101464GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-07101464GO:0009804
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 DCXR

9.68e-07261465GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 DCXR

9.68e-07261465GO:0006063
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.64e-06131464GO:0009812
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A8 UGT1A7 UGT1A9

3.44e-0651463GO:0052696
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-05211464GO:0052695
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-05211464GO:0042447
GeneOntologyBiologicalProcesscerebellum morphogenesis

ABL2 HERC1 MAP2K1 AGTPBP1 PCNT

6.62e-05601465GO:0021587
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A8 UGT1A7 UGT1A9

7.29e-05121463GO:0052697
GeneOntologyBiologicalProcesshindbrain morphogenesis

ABL2 HERC1 MAP2K1 AGTPBP1 PCNT

9.04e-05641465GO:0021575
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.47e-05341464GO:0006706
Domain-

HEATR4 CKAP5 TOGARAM1 ZYG11B HEATR5A EFR3A RIF1 ARID1B ARVCF GCN1 AGTPBP1

1.40e-06222146111.25.10.10
DomainARM-like

HEATR4 CKAP5 TOGARAM1 ZYG11B HEATR5A EFR3A RIF1 ARID1B ARVCF GCN1 AGTPBP1

9.19e-0627014611IPR011989
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.93e-05211464PF00201
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.93e-05211464PS00375
DomainUDP_glucos_trans

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.93e-05211464IPR002213
DomainSecretoglobin_1C1/2

SCGB1C2 SCGB1C1

6.07e-0521462IPR028659
DomainARM-type_fold

DOCK1 HEATR4 CKAP5 TOGARAM1 ZYG11B HEATR5A EFR3A RIF1 ARVCF GCN1 AGTPBP1

7.41e-0533914611IPR016024
DomainMalic_OxRdtase

ME1 ME3

1.81e-0431462IPR001891
DomainMalic_NAD-bd

ME1 ME3

1.81e-0431462IPR012302
DomainMalic_N_dom

ME1 ME3

1.81e-0431462IPR012301
DomainMALIC_ENZYMES

ME1 ME3

1.81e-0431462PS00331
DomainMalic_M

ME1 ME3

1.81e-0431462PF03949
DomainMalic_M

ME1 ME3

1.81e-0431462SM00919
Domainmalic

ME1 ME3

1.81e-0431462PF00390
Domain-

ME1 ME3

1.81e-04314623.40.50.10380
Domainmalic

ME1 ME3

1.81e-0431462SM01274
DomainMalic_enzyme_CS

ME1 ME3

1.81e-0431462IPR015884
DomainHEAT_REPEAT

HEATR4 CKAP5 TOGARAM1 HEATR5A GCN1

2.19e-04701465PS50077
DomainDUF1908

MAST2 MAST3

3.60e-0441462PF08926
DomainMA_Ser/Thr_Kinase_dom

MAST2 MAST3

3.60e-0441462IPR015022
DomainMAST_pre-PK_dom

MAST2 MAST3

3.60e-0441462IPR023142
Domain-

MAST2 MAST3

3.60e-04414621.20.1480.20
DomainHEAT

HEATR4 CKAP5 TOGARAM1 GCN1

1.10e-03581464IPR000357
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 DCXR

2.05e-06281085M19580
PathwayWP_ESTROGEN_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.14e-05221084MM15888
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.08e-05241084MM14599
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.64e-05251084M17787
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.64e-05251084MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.64e-05251084M605
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UPP1

4.27e-05511085M17726
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.28e-05261084M39404
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

MGAM UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.69e-05521085M14171
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A10 UGT1A8 UGT1A9

1.50e-04141083M39328
PathwayREACTOME_PARACETAMOL_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.18e-04391084MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.65e-04411084M7399
PathwayREACTOME_ASPIRIN_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.81e-04451084MM15694
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ST7 RNF213 ZYG11B ME1 CLCC1 IWS1 EFR3A FANCD2 RIF1 ARID1B STXBP3 ARVCF P4HB AHNAK INTS11 PHLPP1 CDK5RAP2 HERC1 RPA3 L3MBTL3 GCN1 AGTPBP1 PCNT

2.13e-1010491522327880917
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

MID2 ACLY ERO1A SERPINH1 CLCC1 EDEM3 GSPT2 P4HB TMEM131 TTC13 HERC1 GCN1 PCNT

4.54e-102851521332838362
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.22e-096152432527940
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.22e-096152420297805
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.21e-08715248467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.21e-08715248464825
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.21e-087152427514509
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.42e-088152420610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.42e-088152418052087
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.42e-088152417179145
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACLY RSF1 CKAP5 SRP72 CHD1 DDX51 SERPINH1 GFPT1 RIF1 PBRM1 DST P4HB AHNAK PDCD11 GCN1 PCNT

3.22e-086531521622586326
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ERO1A SRP72 ZYG11B EXOSC2 CLCC1 GSPT1 FANCD2 EDEM3 IBTK STXBP3 SBNO1 P4HB GORASP1 CDK5RAP2 MTX1 GCN1 PCNT

3.89e-087541521733060197
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.34e-089152422511988
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.22e-0810152423642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.22e-0810152411465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.22e-0810152423371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.22e-0810152422558097
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A10 UGT1A8 UGT1A9

8.18e-083152312847094
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A10 UGT1A8 UGT1A9

8.18e-083152329519853
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.69e-0712152420308471
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.69e-0712152419419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.69e-0712152411434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.43e-0713152422085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.43e-0713152425246029
Pubmed

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

UGT1A10 UGT1A7 UGT1A9

3.26e-074152317558305
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.39e-0714152421646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.39e-0714152410836148
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.39e-071415249295054
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.39e-0714152414672974
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ACLY ERO1A NIF3L1 SRP72 VPS26A SERPINH1 ME1 EXOSC2 GFPT1 GSPT1 IWS1 FANCD2 S100A13 GSPT2 SBNO1 P4HB ASMTL AHNAK HERC1 SEPTIN7 RPA3 GCN1

4.00e-0714551522222863883
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-0716152419414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.98e-0717152420639394
Pubmed

Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

UGT1A8 UGT1A7 UGT1A9

8.13e-075152320565459
Pubmed

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

UGT1A10 UGT1A8 UGT1A9

8.13e-075152315057901
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.02e-0618152420056724
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PRKD2 ACLY ERO1A CKAP5 SRP72 CHD1 MAST2 SERPINH1 GFPT1 NDUFV1 GSPT1 FANCD2 RIF1 PBRM1 STXBP3 SBNO1 P4HB INTS11 PDCD11 SEPTIN7 GCN1

1.14e-0614251522130948266
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.29e-0619152423281178
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

EP400 CKAP5 MAST2 MAGI2 DST CDK5RAP2 MAST3

1.79e-06130152712421765
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ST7 ERO1A CHD1 NDUFV1 CLCC1 SH3BP4 EFR3A STXBP3 P4HB PDCD11 CDK5RAP2 TMEM131 TTC13 C9orf72 MAP2K1 EIF2AK3 DCXR MRPL1 AGTPBP1 MAST3 PCNT

2.22e-0614871522133957083
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ST7 RNF213 SRP72 NDUFV1 CLCC1 FANCD2 IBTK DST ATXN3 PDCD11 CDK5RAP2 TMEM131 TTC13 HERC1 C9orf72 MTX1 RPA3 EIF2AK3 DCXR MRPL1 PCNT

2.44e-0614961522132877691
Pubmed

The Repeat Expansion Diseases: The dark side of DNA repair.

TCF4 ATXN7 ATXN3 C9orf72

2.91e-0623152426002199
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DOCK1 ABL2 ACLY CKAP5 SRP72 GFPT1 CLCC1 DENND4C EFR3A DST AHNAK SEPTIN7 GCN1 EIF2AK3

3.04e-067081521439231216
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.48e-0624152424625756
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PRKD2 CKAP5 VPS26A RAD54L2 GFPT1 ME3 MAGI2 ZNF18 DST SBNO1 COG1 ASB3 OSBPL1A MKLN1 TMEM131 PCMTD2 SEPTIN7 AGTPBP1 PCNT

3.67e-0612851521935914814
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EP400 ERO1A RNF213 CHD1 CLCC1 DENND4C EDEM3 IBTK ARID1B CNOT6L STXBP3 TMEM131 TTC13 AGTPBP1

4.52e-067331521434672954
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DPYSL5 ZYG11B EXOSC2 DENND4C SH3BP4 RIF1 CNOT6L SBNO1 NEK5 P4HB AHNAK OSBPL1A MKLN1 SNAPC1 SEPTIN7 RPA3 GCN1 MAST3 ARHGAP19

5.45e-0613211521927173435
Pubmed

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.

UGT1A10 UGT1A8 UGT1A9

6.74e-069152320732626
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

SRP72 ZYG11B EXOSC2 CLCC1 EDEM3 SBNO1 GORASP1 CDK5RAP2 PCNT

7.10e-06298152932353859
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

EP400 RSF1 CHD1 KNOP1 IWS1 IBTK PBRM1 AHNAK PCMTD2 L3MBTL3 GCN1

7.51e-064691521127634302
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EP400 CKAP5 SRP72 CHD1 DDX51 SERPINH1 EXOSC2 NDUFV1 KNOP1 IWS1 EFR3A GREB1L RIF1 PBRM1 DST CNOT6L P4HB ATXN7 INTS11 PDCD11

8.99e-0614971522031527615
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TCF4 EP400 SERPINH1 GSPT1 FANCD2 IBTK ARID1B PBRM1 PCMTD2 GCN1

1.05e-053961521026687479
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK1 ACLY CHD1 SERPINH1 CLCC1 GSPT1 KNOP1 S100A13 RIF1 P4HB SYDE2 AHNAK SEPTIN7 GCN1 ARHGAP19

1.28e-059161521532203420
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A8 UGT1A7 UGT1A9

1.32e-0511152318695635
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

MGAM ANK1 ACLY CKAP5 EXOSC2 P4HB GCN1

1.63e-05182152731067453
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EP400 CKAP5 RNF213 RAD54L2 RIF1 PBRM1 P4HB AHNAK GCN1

1.68e-05332152932786267
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

ST7 ERO1A RNF213 SRP72 SERPINH1 EXOSC2 CLCC1 GSPT1 IWS1 FANCD2 DST CNOT6L COG1 AHNAK PDCD11 PCMTD2 RPA3 GCN1 MRPL1

1.82e-0514401521930833792
Pubmed

SCGB1C1 Plays a Critical Role in Suppression of Allergic Airway Inflammation through the Induction of Regulatory T Cell Expansion.

SCGB1C2 SCGB1C1

1.90e-052152238892470
Pubmed

Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.

GSPT1 GSPT2

1.90e-052152215987998
Pubmed

Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.

HERC1 AGTPBP1

1.90e-05215223678603
Pubmed

Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species.

ME1 ME3

1.90e-052152233619771
Pubmed

Functional roles of the tetramer organization of malic enzyme.

ME1 ME3

1.90e-052152219416979
Pubmed

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.

UGT1A7 UGT1A9

1.90e-052152211677206
Pubmed

Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics.

ATXN7 ATXN3

1.90e-052152212944423
Pubmed

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

UGT1A10 UGT1A8

1.90e-052152210497143
Pubmed

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.

UGT1A7 UGT1A9

1.90e-052152212944498
Pubmed

Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

UGT1A7 UGT1A9

1.90e-052152217529886
Pubmed

Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.

ATXN7 ATXN3

1.90e-052152226210447
Pubmed

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

UGT1A10 UGT1A9

1.90e-052152225547628
Pubmed

Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis.

CDK5RAP2 PCNT

1.90e-052152224466316
Pubmed

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.

UGT1A10 UGT1A8

1.90e-052152211901093
Pubmed

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

UGT1A10 UGT1A9

1.90e-052152222031623
Pubmed

Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix.

CDK5RAP2 PCNT

1.90e-052152233170211
Pubmed

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

UGT1A8 UGT1A9

1.90e-052152218568343
Pubmed

Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.

UGT1A10 UGT1A8

1.90e-052152217603215
Pubmed

UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.

UGT1A7 UGT1A9

1.90e-052152215709193
Pubmed

ERO1-PDI Redox Signaling in Health and Disease.

ERO1A P4HB

1.90e-052152234074138
Pubmed

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

TCF4 ARRDC4

1.90e-052152234916487
Pubmed

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.

GSPT1 GSPT2

1.90e-052152224981173
Pubmed

Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.

UGT1A10 UGT1A8

1.90e-05215229647757
Pubmed

How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?

UGT1A10 UGT1A9

1.90e-052152220089735
Pubmed

Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase.

ERO1A P4HB

1.90e-052152227703014
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EP400 ACLY RSF1 CKAP5 CHD1 DDX51 VPS26A SERPINH1 GFPT1 GSPT1 RIF1 DST ARVCF P4HB AHNAK INTS11 PDCD11 GCN1

2.76e-0513531521829467282
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EP400 RNF213 CLCC1 KNOP1 SH3BP4 CASP12 RIF1 DST SYDE2 AHNAK CDK5RAP2 DEPDC7 GCN1

3.98e-057771521335844135
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

EP400 RSF1 RNF213 CHD1 SERPINH1 EXOSC2 GFPT1 IWS1 FANCD2 RIF1 PBRM1 SBNO1 AHNAK UPP1 RPA3

4.11e-0510141521532416067
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

CKAP5 FANCD2 PBRM1 STXBP3 AHNAK GCN1 AGTPBP1

4.74e-05215152735973513
Pubmed

Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.

ARRDC4 CLCC1 STXBP3

5.32e-0517152321897333
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 CKAP5 SRP72 GSPT1 FANCD2 RIF1 AHNAK SEPTIN7 DEPDC7 GCN1 PCNT

5.43e-055821521120467437
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ACLY ERO1A NIF3L1 SRP72 SERPINH1 EXOSC2 GFPT1 NDUFV1 EDEM3 DST P4HB AHNAK PDCD11 TTC13 SEPTIN7 MAP2K1 DCXR

5.62e-0512971521733545068
Pubmed

Polymorphisms and mutations in vWF and ADAMTS13 genes and their correlation with plasma levels of FVIII and vWF in patients with deep venous thrombosis.

ADAMTS13 F8

5.68e-053152220682599
Pubmed

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

UGT1A7 UGT1A9

5.68e-053152216636344
Pubmed

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

UGT1A10 UGT1A9

5.68e-053152220007669
Pubmed

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

UGT1A10 UGT1A8

5.68e-053152219244109
Pubmed

Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase.

CDK5RAP2 PCNT

5.68e-053152234233584
Pubmed

Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR.

CASP12 EIF2AK3

5.68e-053152215542627
Pubmed

Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer.

SERPINH1 PHLPP1

5.68e-053152232587773
Pubmed

Polypeptide chain release factor eRF3 is a novel molecular partner of survivin.

GSPT1 GSPT2

5.68e-053152223377885
Pubmed

Glutathione peroxidase 7 utilizes hydrogen peroxide generated by Ero1α to promote oxidative protein folding.

ERO1A P4HB

5.68e-053152223919619
Pubmed

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.

UGT1A8 UGT1A9

5.68e-053152219225446
Pubmed

Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII.

ADAMTS13 F8

5.68e-053152223636243
Pubmed

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13.

ADAMTS13 F8

5.68e-053152218492805
InteractionFPR1 interactions

RNF213 DPH6 EFR3A FANCD2 EDEM3 RIF1 COG1 MTX1 GCN1

1.42e-061471489int:FPR1
Cytoband2q37

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.39e-063115242q37
GeneFamilyUDP glucuronosyltransferases

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.78e-0532894363
GeneFamilyAtaxins|MJD deubiquinating enzymes

ATXN7 ATXN3

3.55e-046892411
GeneFamilyPDZ domain containing

MAST2 MAGI2 GORASP1 AHNAK MAST3

9.25e-041528951220
GeneFamilySecretoglobins

SCGB1C2 SCGB1C1

2.10e-0314892734
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

DOCK1 RSF1 SLC10A7 GFPT1 EFR3A IBTK RIF1 C17orf75 SBNO1 ATXN3 MKLN1 AGTPBP1

3.12e-0633014612DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 RSF1 SLC10A7 GFPT1 GSPT1 EFR3A IBTK C17orf75 ATXN3 MKLN1 L3MBTL3 GCN1 AGTPBP1

3.77e-0639714613gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000

RNF213 PIWIL2 MSH4 GREB1L MAGI2 RIF1 HERC1 C9orf72 DNAH8

4.22e-061791469gudmap_developingGonad_e14.5_ ovary_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

DOCK1 SLC10A7 GFPT1 EFR3A IBTK C17orf75 ATXN3 MKLN1 L3MBTL3 AGTPBP1

4.65e-0623114610gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

DOCK1 TCF4 RSF1 CKAP5 CHD1 ZYG11B HEATR5A GSPT1 IWS1 RIF1 DST COG1 TMEM131

2.23e-0546914613Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000

RNF213 MSH4 GREB1L MAGI2 RIF1 STXBP3 DDX3Y HERC1 C9orf72

3.14e-052301469gudmap_developingGonad_e18.5_ovary_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

DOCK1 CHD1 SLC10A7 LDAH GFPT1 EFR3A IBTK MKLN1 L3MBTL3 GCN1 AGTPBP1

5.08e-0536914611DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_500

RNF213 MSH4 GREB1L MAGI2 DDX3Y HERC1

1.32e-041131466gudmap_developingGonad_e16.5_ovary_500_k3
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000

RNF213 MSH4 GREB1L MAGI2 RIF1 DDX3Y HERC1 C9orf72

1.40e-042191468gudmap_developingGonad_e16.5_ovary_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

RSF1 TOGARAM1 CHD1 GFPT1 PCDH20 IWS1 RIF1 CNOT6L STXBP3 OSBPL1A CMTR2 L3MBTL3

1.56e-0449214612gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

DPYSL5 GSPT2 STXBP3 ARVCF SYT11 INTS11 PHLPP1 C9orf72 ALG6 PHTF1

1.59e-0435014610Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500

TCF4 DPYSL5 ME1 KNOP1 GREB1L DST GSPT2 MAPK12 ARVCF SYT11 ATXN3 PHLPP1

1.65e-0449514612Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000

TCF4 RSF1 DPYSL5 LHPP HEATR5A ME1 KNOP1 GREB1L DST GSPT2 MAPK12 ARVCF SYT11 ATXN3 PHLPP1 PLAGL2 MTX1 GCN1

1.66e-0499414618Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2

TCF4 DPYSL5 GSPT2 ARVCF SYT11 PHLPP1

2.00e-041221466Facebase_RNAseq_e8.5_Floor Plate_1000_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

TCF4 RSF1 TOGARAM1 CHD1 GFPT1 PCDH20 IWS1 MAGI2 RIF1 DST CNOT6L STXBP3 OSBPL1A DDX3Y CMTR2 L3MBTL3

2.11e-0483614616gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000

DOCK1 PRKD2 TCF4 MID2 RNF213 F8 DPH6 CASP12 S100A13 MAPK12 STXBP3 AHNAK PHLPP1 DDX3Y UPP1 NR3C2

2.55e-0485014616gudmap_kidney_adult_RenMedVasc_Tie2_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

ABL2 RNF213 SRP72 PIWIL2 MSH4 GREB1L MAGI2 RIF1 CNOT6L STXBP3 SBNO1 DDX3Y PCMTD2 HERC1 C9orf72

3.11e-0477814615gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

RNF213 LHPP DENND4C GREB1L MAGI2 CFAP54 SRL C9orf72

3.54e-042511468gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000
ToppCellIPF-Myeloid-cMonocyte|IPF / Disease state, Lineage and Cell class

JDP2 CHD1 FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

1.97e-081901529a099f51f2b7618b6712af38eedd5ee64d8663a4a
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

2.38e-071841528ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellControl-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

TCF4 CHD1 FAM157C AIF1 FAM157A MAP2K1 AGTPBP1 MX2

2.81e-07188152847126c371a242c937499fd278a74a882df8f759c
ToppCellIPF-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

3.04e-071901528ffa890138394f579fee53fcfac6c121bf86adc26
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

RSF1 CKAP5 SRP72 HEATR5A DENND4C GSPT1 EFR3A PBRM1

3.43e-071931528abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

3.43e-071931528936ca95995599356b794fba32bfd82d8de339365
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

JDP2 CHD1 FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1

3.57e-071941528f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

CHD1 FAM157C FAM157A C9orf72 MAP2K1 L3MBTL3 AGTPBP1 MX2

3.71e-071951528fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

FAM157C AIF1 FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

4.00e-061891527d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellCOPD-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

CHD1 FAM157C FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

4.00e-0618915276294691231c7d38707323cf31578a107d3b2c622
ToppCellIPF-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

CHD1 FAM157C FAM157A C9orf72 MAP2K1 AGTPBP1 MX2

4.00e-061891527ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A MAP2K1 AGTPBP1 MX2

4.14e-061901527aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellIPF-Myeloid-ncMonocyte|IPF / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A MAP2K1 AGTPBP1 MX2

4.43e-061921527e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF213 CHD1 CNOT6L ATXN7 AHNAK DDX3Y HERC1

4.43e-06192152747646d7e4990be85072987f92bf18d52f8da752e
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A MAP2K1 AGTPBP1 MX2

4.43e-061921527ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF4 ACLY LDAH SYT11 P4HB DDX3Y SEPTIN7

5.79e-062001527fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TCF4 RNF213 SERPINH1 MYCBPAP DST AHNAK OSBPL1A

5.79e-06200152779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DCLRE1B CLCC1 FANCD2 DST ASB3 CDK5RAP2

3.08e-051751526da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPGS2 FANCD2 IBTK ATXN3 MX2 ARHGAP19

3.18e-05176152690f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

RNF213 ARID1B AHNAK MKLN1 DDX3Y HERC1

3.72e-051811526f2315414e714ac86211546a935660c4be6e85f1b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RNF213 CHD1 ARID1B TMEM131 HERC1 EIF2AK3

4.60e-051881526ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HEATR5A CLCC1 CCDC7 ZNF18 CDK5RAP2 L3MBTL3

4.73e-051891526c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DBH ME3 SRL PZP ALPK2

4.73e-051891526e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A AGTPBP1 MX2

4.73e-0518915265c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DBH ME3 SRL PZP ALPK2

4.73e-051891526b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIWIL2 GFPT1 EDEM3 S100A13 HPD MVB12B

4.73e-0518915265a0fd34928117f162c83ca1b068aa8f7069a6765
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HCAR2 JDP2 AHNAK UPP1 C9orf72 AGTPBP1

4.73e-05189152655aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH20 GJB1 ARVCF DEPDC7 L3MBTL3 ARHGAP19

4.73e-0518915260493f7b79127c207fd7ade778ef4810500495d7e
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A AGTPBP1 MX2

4.87e-051901526ed978cd5d9da87b49878a330e362762c487f849f
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

CHD1 FAM157C AIF1 FAM157A AGTPBP1 MX2

4.87e-051901526f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HCAR2 JDP2 AHNAK UPP1 C9orf72 MX2

5.02e-05191152663d4226a8b59f648bdc9f41e4b2d750dfa342034
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DBH ME3 SRL ALPK2 SCGB1C1

5.17e-051921526f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DBH ME3 SRL ALPK2 SCGB1C1

5.17e-0519215261a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LHPP PCDH20 S100A13 GJB1 DST SYT11

5.32e-051931526947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCellMacrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DENND4C S100A13 DST AIF1 DDX3Y UPP1

5.47e-05194152654fda501ce1d041285d04c3c96c15983f454bed4
ToppCellControl-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

FAM157C FAM157A C9orf72 MAP2K1 L3MBTL3 AGTPBP1

5.63e-051951526b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCellmLN-T_cell-gd_T|T_cell / Region, Cell class and subclass

TMEM116 SLC10A7 SH3BP4 S100A13 MAPK12 SYT11

5.79e-0519615268f476408cd5a4ea9d25c763c66565343d7989b38
ToppCellmLN-(1)_T_cell-(17)_gd_T|mLN / shred on region, Cell_type, and subtype

TMEM116 SLC10A7 SH3BP4 S100A13 MAPK12 SYT11

5.96e-0519715265c781ded147db2f3804ee1f21ef0898c4f354890
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK1 LHPP GJB1 DST OSBPL1A MVB12B

5.96e-05197152682b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellmLN-T_cell-gd_T|mLN / Region, Cell class and subclass

TMEM116 SLC10A7 SH3BP4 S100A13 MAPK12 SYT11

5.96e-0519715268ef03bdbd34a874671aebfdbb7111106aa37b2a9
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM HCAR2 CHD1 AIF1 C9orf72 MX2

5.96e-0519715263cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 MAGI2 ARID1B MKLN1 NR3C2 HERC1

6.30e-05199152694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 TCF4 RNF213 SERPINH1 DST AHNAK

6.48e-05200152672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 TCF4 RNF213 SERPINH1 DST AHNAK

6.48e-0520015265c092b2ecc081b5d04476c56333c338cd89ab984
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GSPT2 SYT11 PHLPP1 PLAGL2 EIF2AK3

9.02e-05132152514a512f433315892bf0326419f23d0d5919d01ec
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

CYP2J2 HEATR5A GREB1L GORASP1 AHNAK

9.69e-0513415252647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM1 LHPP MAST2 GFPT1 GORASP1

1.04e-041361525a43b3db1754c619d328a26a2ba6af4756629a723
Drugnaringenin chalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.53e-0951484ctd:C027329
Druganthrarobin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.53e-0951484ctd:C032186
Drug1,2,5,8-tetrahydroxy anthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.55e-0861484ctd:C543211
Drugalloin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.55e-0861484ctd:C006457
Drug2',5'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.55e-0861484ctd:C107497
Drug2',4'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.91e-0871484ctd:C059354
DrugSureCN12722713

UGT1A10 UGT1A8 UGT1A7 UGT1A9 HPD

8.68e-08181485CID005488034
Drug1,4-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.18e-0781484ctd:C034890
Drugtectochrysin

MGAM UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.55e-07201485CID005281954
DrugAC1MRQNQ

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.11e-0791484CID003522271
DrugDHPASiU

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.11e-0791484CID000197602
Drug3-iodophenol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.11e-0791484CID000012272
DrugAC1L4J7U

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.11e-0791484CID000186631
DrugChebi:32663

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.11e-0791484CID005460873
Drug2,6-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.49e-07101484ctd:C034889
Drug4-nitrophenyl)imidazole

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.46e-07111484CID000123155
DrugAC1O5XMV

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.46e-07111484CID006442661
DrugUDP-glucose

MGAM HCAR2 UGT1A10 UGT1A8 UGT1A7 UGT1A9 NIF3L1 GFPT1 AIF1 UPP1 ALG6

6.78e-0724714811CID000001166
DrugAC1L1G0K

UGT1A10 UGT1A8 UGT1A7 JDP2 UGT1A9 MAPK12

7.57e-07491486CID000003473
DrugN-OH-DABZ

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484CID000088735
Drug4-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484ctd:C026418
Drug2,4,6-TCB

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484CID000037247
Drugnonanoyl-N-methylglucamide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484CID000160090
Drug7,7,7-triphenylheptanoic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.15e-07121484CID000276709
Drugerucin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 MAP2K1

9.45e-07281485CID000078160
Drughydratropic acid

UGT1A10 UGT1A8 UGT1A7

1.07e-0641483ctd:C013025
Drug2-vanillin

UGT1A10 UGT1A8 UGT1A7

1.07e-0641483ctd:C060843
Drugdiphenylacetic acid

UGT1A10 UGT1A8 UGT1A7

1.07e-0641483ctd:C037760
DrugAC1L1JAL

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GFPT1

1.14e-06291485CID000004954
Drugiberin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 DBH

1.14e-06291485CID000010455
Drug2-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.17e-06131484ctd:C024980
Drugtritanol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.17e-06131484CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.17e-06131484CID003081279
Drugcotinine-N-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.17e-06131484CID000000411
Drugalizarin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.17e-06131484ctd:C010078
Drug4-ethylphenol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 MAPK12

1.61e-06311485CID000031242
Drugpropranolol glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.63e-06141484CID000119515
DrugPCB-61

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.63e-06141484CID000036401
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484CID000040469
Drugafloqualone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484CID000002040
Drugnaphthyl sulphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484CID000114775
Drugcoumarin-3-carboxylic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484CID000010752
Drugbergamottin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484ctd:C068337
Drugsulforaphane nitrile

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.21e-06151484CID000543743
DrugAC1Q6OQG

UGT1A10 UGT1A8 UGT1A7 UGT1A9 NR3C2

2.22e-06331485CID000009686
Drugisovaleric acid

UGT1A10 UGT1A8 UGT1A7

2.67e-0651483ctd:C008216
Drugbiphenylylacetic acid

UGT1A10 UGT1A8 UGT1A7

2.67e-0651483ctd:C012776
Drugquercetin-3,4'-diglucoside

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.94e-06161484CID005320835
Drug1'-hydroxyestragole

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.94e-06161484CID000040003
Drugbilirubin-phosphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.94e-06161484CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.82e-06171484CID000003573
Drug6-hydroxychrysene

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.82e-06171484CID000037766
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID000152226
DrugBr 2

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID003060900
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID000036614
DrugApApG

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID003081975
DrugC1 11-32

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID000443077
DrugC11131

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.89e-06181484CID000443076
Drug3-phenylpropionic acid

UGT1A10 UGT1A8 UGT1A7

5.31e-0661483ctd:C035253
DrugIndoprofen

UGT1A10 UGT1A8 UGT1A7

5.31e-0661483ctd:D007216
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; HL60; HG-U133A

TCF4 RSF1 ME1 CLCC1 EFR3A IBTK C17orf75 SBNO1 ATXN7

5.42e-0619514891370_UP
Drug9-OH-risperidone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.16e-06191484CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.16e-06191484CID000091433
Drugalmokalant

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.16e-06191484CID003033962
Drugnitrosamine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 PBRM1 AGTPBP1

6.34e-06701486CID000037183
DrugAC1L1OBF

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.66e-06201484CID000032736
Drug4'-hydroxydiclofenac

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.66e-06201484CID000116545
Drugentacapone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.66e-06201484ctd:C071192
DrugWoodward's reagent K

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UPP1

8.56e-06431485CID000077804
Drugestriol-16-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.41e-06211484CID000122281
Drugdulcin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.41e-06211484CID000009013
DrugBenzamidoxime hydrochloride

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.41e-06211484CID000069186
Drugamonafide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.14e-05221484CID000050515
DrugN-methylpiperazine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.14e-05221484CID000053167
Drugplumbagin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.14e-05221484ctd:C014758
Drugamidoxime

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.38e-05231484CID000465967
Drugestradiol-3-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.38e-05231484CID000066651
Drugphenanthridine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.38e-05231484CID000009189
Drugglabridin

UGT1A10 UGT1A8 UGT1A9

1.47e-0581483ctd:C107601
Drugisoamyl alcohol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 CHD1

1.48e-05481485CID000031260
Drugcinnamic acid

HCAR2 UGT1A10 UGT1A8 UGT1A7

1.65e-05241484ctd:C029010
DrugAS-3201

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.65e-05241484CID000153948
Drug5-MOP

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484CID000002355
DrugHymecromone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484ctd:D006923
DrugAzMC

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484CID000064986
DrugN-acetylbenzidine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484CID000018787
Drug5,6-benzoquinoline

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484CID000006796
DrugN-phenylmaleimide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.95e-05251484CID000013662
Drug7-ethoxycoumarin

CYP2J2 UGT1A10 UGT1A8 UGT1A7 UGT1A9 PCNT

2.09e-05861486CID000035703
DrugAC1L1FK5

UGT1A10 UGT1A8 UGT1A7 UGT1A9 NR3C2 PZP EPHA1

2.19e-051291487CID000003272
DrugAC1NQGK1

MGAM UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.20e-05521485CID005195977
DrugThymol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.29e-05261484ctd:D013943
DrugASA404

UGT1A10 UGT1A8 UGT1A7 UGT1A9 RIF1

2.42e-05531485CID000123964
DrugDEPC

MGAM UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.42e-05531485CID000015357
Drugluteolin

MGAM UGT1A10 UGT1A8 UGT1A7 UGT1A9 GFPT1 ALPK2

2.42e-051311487CID005280445
Drugtangeretin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 MAPK12

2.65e-05541485CID000068077
DrugEquol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 ME1

2.65e-05541485ctd:D060754
Druglicochalcone A

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.68e-05271484ctd:C070840
Drugdiflunisal

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.68e-05271484CID000003059
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.20e-0951504EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.20e-0951504EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.20e-0951504EFO_0801853
DiseaseX-21339 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.22e-0871504EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0021260
DiseaseSuccinimide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0022118
DiseaseX-11530 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0800696
DiseaseX-10458 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0800692
DiseaseX-24849 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0600043
Diseaseplasma clozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0802740
DiseaseX-16946 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.42e-0881504EFO_0800766
DiseaseX-11442 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0021236
DiseaseX-11441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0801036
DiseaseX-11880 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.93e-0891504EFO_0004570, GO_0009410
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A8 UGT1A9

1.29e-0731503EFO_0800043
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A8 UGT1A9

1.29e-0731503EFO_0022216
Diseasebilirubin measurement, response to tenofovir

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.32e-07101504EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.32e-07101504EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.32e-07101504EFO_0802185
DiseaseX-23974 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.32e-07101504EFO_0800867
Diseasepregnenetriol sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0600039
Diseasehistidine betaine (hercynine) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0800972
DiseaseX-21796 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-07111504EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.08e-07121504EFO_0800079
Diseasebiliverdin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.08e-07121504EFO_0021033
Diseasepregnenetriol disulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.43e-07131504EFO_0800587
DiseaseX-24588 measurement

UGT1A10 UGT1A8 HEATR4 UGT1A9

4.43e-07131504EFO_0800898
Diseaseretinol dehydrogenase 16 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.43e-07131504EFO_0802007
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.45e-06171504EFO_0004611, EFO_0007800
DiseaseX-21441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.45e-06171504EFO_0800814
Diseaseangiopoietin-related protein 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.86e-06181504EFO_0801382
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A8 UGT1A9

2.55e-0661503EFO_0800566
Diseasetissue factor measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-06211504EFO_0010623
Diseasehormone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 ASB3 MVB12B

4.58e-06841506EFO_0004730
Diseaseneuroblastoma, cutaneous melanoma

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.19e-05281504EFO_0000389, EFO_0000621
Diseasexanthurenate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.38e-05291504EFO_0010551
Diseaseindoleacetate measurement

UGT1A10 UGT1A8 UGT1A9

1.51e-05101503EFO_0021015
Diseaseresponse to dolutegravir

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.59e-05301504EFO_0600017
DiseaseParanoia

TCF4 DBH DNAH8

2.06e-05111503C1456784
Diseasevitamin D deficiency

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.72e-05371504EFO_0003762
Diseasecholelithiasis

UGT1A10 UGT1A8 UGT1A7 UGT1A9 SH3BP4

8.86e-05881505EFO_0004799
Diseasevitamin D measurement, COVID-19

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.14e-04491504EFO_0004631, MONDO_0100096
Diseaselate-onset Alzheimers disease

UGT1A10 UGT1A8 ERO1A CKAP5 CASP12 AHNAK ASB3 EPHA1

1.31e-042921508EFO_1001870
Diseaseautoimmune disease (implicated_via_orthology)

AHNAK C9orf72

1.53e-0441502DOID:417 (implicated_via_orthology)
DiseaseMachado-Joseph disease (implicated_via_orthology)

GFPT1 ATXN3

1.53e-0441502DOID:1440 (implicated_via_orthology)
Diseaseurate measurement, spine bone mineral density

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.20e-04581504EFO_0004531, EFO_0007701
Diseasegallstones

UGT1A10 UGT1A8 UGT1A7 UGT1A9 SH3BP4

2.32e-041081505EFO_0004210
DiseaseNonorganic psychosis

TCF4 PBRM1 C9orf72 PCNT

4.29e-04691504C0349204
Diseaseapolipoprotein B measurement

ANK1 UGT1A10 UGT1A8 UGT1A7 DPYSL5 UGT1A9 LDAH CLCC1 STXBP3 PCMTD2 L3MBTL3

6.03e-0466315011EFO_0004615
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3P1 MEIS3P2

7.04e-0481502DOID:0050425 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 PBRM1 SBNO1 SYT11 AHNAK L3MBTL3 GCN1 ALPK2 MAST3 EPHA1

8.22e-0491415013EFO_0004532
Diseasethyroxine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.63e-04831504EFO_0005130
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A10 UGT1A8 UGT1A7 UGT1A9 CASP12

9.50e-041471505DOID:9352 (biomarker_via_orthology)
DiseaseMoyamoya disease

DOCK1 RNF213 MAGI2

1.11e-03401503MONDO_0016820
DiseaseLiver carcinoma

ACLY JDP2 DBH ADAMTS13 ME1 FANCD2 GJB1 ARID1B PZP

1.19e-035071509C2239176
Diseasebitter beverage consumption measurement

MAGI2 EDEM3 PCMTD2

1.28e-03421503EFO_0010089
DiseaseMajor Depressive Disorder

LHPP DBH NDUFV1 NR3C2 MAP2K1 PCNT

1.56e-032431506C1269683
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

1.64e-03121502EFO_0021054
Diseaseurinary bladder carcinoma

UGT1A10 UGT1A8 SH3BP4

1.77e-03471503MONDO_0004986
DiseasePsychotic Disorders

TCF4 PBRM1 C9orf72 PCNT

1.79e-031011504C0033975
Diseasecardiac troponin I measurement

IWS1 CASP12 NR3C2 PZP MVB12B

2.10e-031761505EFO_0010071
DiseaseUnipolar Depression

LHPP DBH NDUFV1 NR3C2 MAP2K1 PCNT

2.16e-032591506C0041696
Diseasesitting height ratio

PRKD2 TCF4 ARID1B

2.24e-03511503EFO_0007118
Diseasemetabolite measurement

UGT1A10 UGT1A8 HEATR4 UGT1A7 UGT1A9 PKD1L2 MAGI2 MAPK12 HPD

2.34e-035601509EFO_0004725
Diseaseanti-neutrophil antibody associated vasculitis

F8 ASB3 PHTF1

2.37e-03521503EFO_0004826
Diseasesleep apnea measurement

ANK1 DENND4C ARID1B ASB3

2.96e-031161504EFO_0007817
Diseaseopen-angle glaucoma

LHPP ME3 DST SEPTIN7 MVB12B

2.99e-031911505EFO_0004190
Diseaselymphocyte count

TCF4 ANK1 JDP2 ME3 PBRM1 ARVCF SBNO1 SCGB1C2 SYT11 AHNAK ASB3 PHLPP1 NR3C2 L3MBTL3 PHTF1 SCGB1C1

3.26e-03146415016EFO_0004587
DiseaseMoyamoya Disease

RNF213 PCNT

3.32e-03171502C0026654
Diseasenon-high density lipoprotein cholesterol measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 HEATR5A DENND4C PBRM1 SBNO1 MTX1 L3MBTL3

3.62e-0371315010EFO_0005689
Diseaseleukemia (implicated_via_orthology)

MEIS3P1 MEIS3P2

4.15e-03191502DOID:1240 (implicated_via_orthology)
Diseasetea consumption measurement

MGAM TCF4 PCMTD2 ALG6

4.32e-031291504EFO_0010091
DiseaseDrug-Induced Liver Disease

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C0860207
DiseaseDrug-Induced Acute Liver Injury

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C3658290
DiseaseHepatitis, Toxic

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C0019193
DiseaseChemically-Induced Liver Toxicity

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C4279912
DiseaseChemical and Drug Induced Liver Injury

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C4277682
DiseaseHepatitis, Drug-Induced

UGT1A9 SRP72 SLC10A7 ME1 HPD P4HB PZP

4.73e-034041507C1262760
Diseasepulse pressure measurement

TCF4 CKAP5 RNF213 HEATR5A MAST2 LDAH DENND4C ARID1B PBRM1 ARVCF ATXN7 ASB3 INTS11 MKLN1 CMTR2

4.97e-03139215015EFO_0005763

Protein segments in the cluster

PeptideGeneStartEntry
VVLKARHLPKMDITG

SYT11

311

Q9BT88
IKAVGKLTPEHLIKM

EP400

2806

Q96L91
LHLEGVVTKRKPIMI

EPHA1

686

P21709
VILGLQEKHLKADIM

CFAP54

2441

Q96N23
PLKMVIIDHGLQTLT

ARVCF

476

O00192
LLMDPELHVGKCKIE

CATSPERD

376

Q86XM0
NLLPEDEMIGKIIKH

CCDC7

76

Q96M83
VMREVKALAKLEHPG

EIF2AK3

636

Q9NZJ5
ITGLPLIKEALIHMD

CYP2J2

91

P51589
MKEIKHPNLVQLLGV

ABL2

336

P42684
LKIKDILPRHIQLIM

ALG6

286

Q9Y672
FLISHKMEEPKIEVL

ALPK2

1621

Q86TB3
GHVKMVVELLHKEII

ANK1

56

P16157
MIIKVAALGLDPDKH

DPH6

161

Q7L8W6
KGREAIHPLLSKMTL

CMTR2

321

Q8IYT2
LHLKAPKISMPEVDL

AHNAK

4586

Q09666
AMETGLLPNHKLKTV

ARID1B

141

Q8NFD5
KIPGTLHKIVSVKLM

DEPDC7

421

Q96QD5
PKMVLLFHLIEESVK

RAD54L2

721

Q9Y4B4
PSNGVLVHMVKLLIK

CASP12

6

Q6UXS9
LMVQIHSILAKIGPK

AGTPBP1

131

Q9UPW5
SMLKEPALTLGKQIH

DCLRE1B

126

Q9H816
IKMDPDLSLTHKILP

CHD1

1276

O14646
LHMVAKLLESGEPKL

EFR3A

101

Q14156
VHLVKMVILTEPEGA

ADAMTS13

126

Q76LX8
GAKKLMLELPLVIGT

ARRDC4

301

Q8NCT1
KHVKILGPLAPEMID

CDK5RAP2

1181

Q96SN8
GLVMARKLIHLEIKP

MAP2K1

91

Q02750
MVLVPSLLHTEAPKK

PZP

31

P20742
LPAVVMHLKKQDLKE

IWS1

591

Q96ST2
TDIVKIMSIKLGPAL

L3MBTL3

746

Q96JM7
THKSLTLGIPMLKIV

SLC10A7

276

Q0GE19
LEVQIPLKGKIDLHM

PCDH20

926

Q8N6Y1
IILEPMDLKIIEHNI

PBRM1

561

Q86U86
HLIVMALEKEGLPKE

ME1

311

P48163
IMKVLLLLSTIPKDG

NR3C2

871

P08235
IHVGKVLPKTGLLMT

MAGEB5

121

Q9BZ81
MPHADIVKLIKDAGL

MAGI2

986

Q86UL8
PKLDQALVVEHIEKM

RASGRP2

416

Q7LDG7
EPESVLLVHGEAKKM

INTS11

406

Q5TA45
IGLTVHLLKKKMPIQ

HCAR2

156

Q8TDS4
LEMPIHSDILKVILD

IBTK

811

Q9P2D0
NHEMVLKDVLPPIIK

DST

2701

Q03001
MVLCPVIGKLLHKRV

ASMTL

1

O95671
KVEMELPGDKIGLHL

MGAM

801

O43451
ELGRMVQLHLKSDKP

TCF4

586

P15884
MHRPKLIGEELAQLK

ATXN3

186

P54252
PEHLEILKKMGVSLI

EDEM3

586

Q9BZQ6
MGVAIRTKKPLDLHL

HERC1

4586

Q15751
MIAPLHFLEVKLGKR

JDP2

46

Q8WYK2
VKHLIVLINKMDDPT

GSPT2

341

Q8IYD1
LKVGGILVMPLEEKL

PCMTD2

181

Q9NV79
KKHVEPMAVRQLLLG

FAM157A

21

C9JC47
IIQEMLEEVGKPKHR

PGPEP1L

166

A6NFU8
EVILLEKMKHPNIVA

NEK5

51

Q6P3R8
KVMALELGPHKIRVN

DCXR

161

Q7Z4W1
IVVGALELHTEPMKL

DNAH8

1056

Q96JB1
LELHTEPMKLALSIE

DNAH8

1061

Q96JB1
KKHVEPMAVRQLLLG

FAM157C

21

P0CG43
IELDKMLLSKVKVPH

PRKD2

251

Q9BZL6
MITKTHKVDLGLPEK

KNOP1

1

Q1ED39
KVDLLAPMIIHGIKT

F8

2091

P00451
VILPAVMLALKEKLG

GCN1

2111

Q92616
VLMELEKPVLISLGK

LHPP

141

Q9H008
FLEGKIKPHLMSQEL

P4HB

346

P07237
KPLDLAQGAEMKHIL

OSBPL1A

211

Q9BXW6
HQIKDILKPEIMEEI

EXOSC2

266

Q13868
GKHLESMRLPLVSDK

GREB1L

1496

Q9C091
DILLKIVKVEHEEMP

C17orf75

361

Q9HAS0
IEKLQHELSLMGPVV

PCNT

1746

O95613
VKVEKIHPKMDGTLL

ATXN7

256

O15265
GVKHLIVLINKMDDP

GSPT1

211

P15170
TLIESHEGKPLKLMV

GORASP1

151

Q9BQQ3
HLGNVLVDMKLIDIK

MVB12B

106

Q9H7P6
VMEHVQTTLLLGKLP

PKD1L2

1041

Q7Z442
RFHLLELEKGKMPID

MEIS3P2

141

A8K0S8
KKHVEPMAVRQLLLG

FAM157B

21

P0CG42
QMGHTKILDLLIPLT

ASB3

256

Q9Y575
KGPKILDHLTMIDNK

CKAP5

1771

Q14008
PHGKGKIIMTLAEDL

HEATR5A

521

Q86XA9
HKIKFIPEMVGPILE

DOCK1

1076

Q14185
GHALPKVTLQEMLKS

COG1

761

Q8WTW3
EMLKEEHKVAVLGVP

nan

21

C9JQL5
KPLVVLHLVLEMGFS

DDX51

491

Q8N8A6
EIRMLKKVVSVHPGD

DBH

446

P09172
MSLGKEVHDIIRVKL

HEATR4

691

Q86WZ0
HLGLLTPVERKMVSK

DENND4C

291

Q5VZ89
IEKKMLRLEGHGDPL

GJB1

101

P08034
KMLLLEILHEIKSFP

ERO1A

341

Q96HE7
LKPDNLLITSMGHIK

MAST2

636

Q6P0Q8
VLGLVHMDVVELLLK

MAST3

1011

O60307
HLLVMALEKEGVPKA

ME3

346

Q16798
KHAIPIIKGKRDLMA

DDX3Y

206

O15523
GEVPKELVELHLKLM

RSF1

61

Q96T23
MPIKLKIGLRHPDAV

SBNO1

246

A3KN83
NIIMALAEKIKPGLH

C9orf72

446

Q96LT7
MIIGHVLPDKETSLV

DPYSL5

96

Q9BPU6
PEMKGKVLTRLKHIV

FANCD2

806

Q9BXW9
LRFHLLELEKGKMPI

MEIS3P1

56

A6NDR6
MSLLEEKLLPVLVHT

MTX1

246

Q13505
PKLPKCSLEMIDHIV

HPD

171

P32754
LPEIEKATLKMLLDH

SYDE2

946

Q5VT97
GIPSISIMLHELIKL

UPP1

111

Q16831
ELHLGLDKMKNPITK

SH3BP4

916

Q9P0V3
LPHLLKDVGSLDEKM

S100A13

46

Q99584
GELKHGPLALVDKLM

GFPT1

591

Q06210
HPMLTDIHDKLVLKG

MKLN1

206

Q9UL63
LQKDVHKIEGRVLPM

PIWIL2

556

Q8TC59
LMEITIKGLPQKVLG

RIF1

551

Q5UIP0
EMSVPLKELIEKHAG

NDUFV1

291

P49821
DGLQPMHKAELVKLL

SCGB1C2

71

P0DMR2
EKLQIVEMPLAHKLS

SERPINH1

251

P50454
HTLELVDPLKIAMKN

MSH4

426

O15457
HSGILPILKEIVEML

SKIV2L

636

Q15477
LVSLMKTLHLEPLKA

PRAMEF2

66

O60811
LRSIEELKHKPGMVS

SRP72

396

O76094
LEMKSLILPPEHILK

ST7

421

Q9NRC1
EILSLEKPLLLHTGM

NIF3L1

236

Q9GZT8
HIAVVLEEIPKLMKE

STXBP3

296

O00186
LEKIHPTGKMFILSD

RPA3

31

P35244
LLKIKTEPVDMLGLL

PLAGL2

246

Q9UPG8
IHKEDKPLSLSMPVI

SNAPC1

331

Q16533
LMTREKHPDGKILII

ACLY

326

P53396
KRMLEKLGVPKTHLE

AIF1

71

P55008
EFIKALMKEIPALLH

CLCC1

321

Q96S66
AGMKPIHAADKQLLI

CNOT6L

341

Q96LI5
LELHEMIILKLKNPQ

RNF213

5131

Q63HN8
IHPGMLLIGFVKSIK

PDCD11

726

Q14690
DVTGPMLLHKAKELA

TIGD3

96

Q6B0B8
PKMLELFKNGHEIKV

MRPL1

231

Q9BYD6
DLIAHLEQGKKPLTM

ZNF93

51

P35789
ALEKVHKVEDLLPIM

TTC13

646

Q8NBP0
LTHVMEKTKPEILKL

ZYG11B

351

Q9C0D3
EKLILRGHEVVVVMP

UGT1A10

46

Q9HAW8
KKMGHIKPDLIDVDL

PHTF1

41

Q9UMS5
GLKPLDIEFMKRLHE

SEPTIN7

171

Q16181
VLMHGPKLKTIEGIV

SRL

136

Q86TD4
ILIHDVLLPEEAKTM

TMEM131

466

Q92545
LMIIKLTKPQDTKLH

TMEM116

156

Q8NCL8
ALSEHLKKPVSELLM

MYCBPAP

221

Q8TBZ2
LKKPVSELLMHTGET

MYCBPAP

226

Q8TBZ2
DGLQPMHKAELVKLL

SCGB1C1

71

Q8TD33
KMFLGELPEPLLTHK

ARHGAP19

181

Q14CB8
EKLILRGHEVVVVMP

UGT1A9

46

O60656
VKLDEHIIPLGSMAI

TPGS2

81

Q68CL5
HMELQLIKKEITGIG

VPS26A

206

O75436
KMHVLPLIGGKVEEV

PHLPP1

581

O60346
VMSGPHETLKQLRKL

ZNF18

51

P17022
PPHIKKSLEELLDMT

TOGARAM1

1701

Q9Y4F4
KEMLVDVPPHLKRLG

MID2

641

Q9UJV3
EKLILRGHEVVVVMP

UGT1A7

46

Q9HAW7
EVPLSHKGKLMVTEE

TYW3

151

Q6IPR3
EKLILRGHEVVVVMP

UGT1A8

46

Q9HAW9
HLDQLKEIMKVTGTP

MAPK12

231

P53778
HVPKDMKLVLIGHSI

LDAH

126

Q9H6V9
TELIMHIQKSLPLLE

MX2

376

P20592