Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acyltransferase activity	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B ZDHHC14 PORCN RNF216 ALAS1 LONRF3 TRIM40 LONRF2 EP300 TRIM3	6.38e-11	775	52	16	GO:0016746
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	2.37e-09	473	52	12	GO:0004842
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRIM33 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	2.47e-09	372	52	11	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	TRIM33 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	4.99e-09	398	52	11	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	5.77e-09	512	52	12	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	8.84e-09	532	52	12	GO:0016755
GeneOntologyMolecularFunction	zinc ion binding	TRIM33 TRIM66 TRAF2 TRAF3 P2RX7 RNF19A RNF112 RNF19B NFXL1 RNF216 TRIM40 EP300 TRIM3	3.21e-07	891	52	13	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	TRIM33 TRIM66 TRAF2 TRAF3 P2RX7 RNF19A RNF112 RNF19B NFXL1 RNF216 TRIM40 EP300 TRIM3	7.96e-06	1189	52	13	GO:0046914
GeneOntologyMolecularFunction	thioesterase binding	TRAF2 TRAF3	2.95e-04	10	52	2	GO:0031996
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF5 PRAMEF6 SMAD7	1.28e-03	82	52	3	GO:1990756
GeneOntologyMolecularFunction	SMAD binding	TRIM33 EP300 SMAD7	1.46e-03	86	52	3	GO:0046332
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF5 PRAMEF6 SMAD7	1.95e-03	95	52	3	GO:0140767
GeneOntologyMolecularFunction	acetylation-dependent protein binding	PSME4 EP300	2.95e-03	31	52	2	GO:0140033
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ZDHHC14 PORCN ALAS1 EP300	3.40e-03	238	52	4	GO:0016747
GeneOntologyMolecularFunction	tumor necrosis factor receptor binding	TRAF2 TRAF3	3.75e-03	35	52	2	GO:0005164
GeneOntologyMolecularFunction	beta-catenin binding	GJA1 EP300 SMAD7	3.77e-03	120	52	3	GO:0008013
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	RNF19A RNF19B	3.96e-03	36	52	2	GO:0031624
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	RNF19A RNF19B	5.36e-03	42	52	2	GO:0044390
GeneOntologyMolecularFunction	tau protein binding	ROCK1 EP300	6.40e-03	46	52	2	GO:0048156
GeneOntologyBiologicalProcess	protein ubiquitination	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 TRIM40 KLHL18 TRIM3 PRAMEF6 SMAD7	4.50e-08	811	50	13	GO:0016567
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 TRIM40 KLHL18 TRIM3 PRAMEF6 SMAD7	1.38e-07	893	50	13	GO:0032446
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 TRIM40 KLHL18 TRIM3 PRAMEF6 SMAD7	5.58e-07	1009	50	13	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B RNF216 TRIM40 KLHL18 TRIM3 PRAMEF6 SMAD7	1.13e-06	1074	50	13	GO:0043687
GeneOntologyBiologicalProcess	protein catabolic process	GJA1 TRAF2 PSME4 P2RX7 RNF19A SH3RF2 RNF19B RNF216 ROCK1 TRIM40 TRIM3 PRAMEF6 SMAD7	1.71e-06	1115	50	13	GO:0030163
GeneOntologyBiologicalProcess	protein autoubiquitination	TRAF2 SH3RF2 RNF112 RNF19B	3.82e-05	78	50	4	GO:0051865
GeneOntologyBiologicalProcess	protein polyubiquitination	TRAF2 TRAF3 RNF19A RNF19B RNF216 TRIM3	6.80e-05	289	50	6	GO:0000209
GeneOntologyBiologicalProcess	blastoderm segmentation	PCSK6 CHRD LAMA5	8.31e-05	35	50	3	GO:0007350
GeneOntologyBiologicalProcess	regulation of ventricular cardiac muscle cell membrane depolarization	GJA1 SMAD7	1.60e-04	8	50	2	GO:0060373
GeneOntologyBiologicalProcess	segmentation	PCSK6 CHRD LAMA5 EP300	2.24e-04	123	50	4	GO:0035282
GeneOntologyCellularComponent	ubiquitin ligase complex	TRAF2 TRAF3 PRAMEF5 RNF19A RNF19B PRAMEF6	2.08e-04	352	51	6	GO:0000151
GeneOntologyCellularComponent	bleb	P2RX7 ROCK1	2.59e-04	10	51	2	GO:0032059
GeneOntologyCellularComponent	CD40 receptor complex	TRAF2 TRAF3	3.16e-04	11	51	2	GO:0035631
GeneOntologyCellularComponent	intracellular protein-containing complex	TRAF2 TRAF3 PRAMEF5 PSME4 RNF19A RNF19B TSEN2 EP300 PRAMEF6	5.12e-04	972	51	9	GO:0140535
MousePheno	abnormal heart septum morphology	GJA1 FRAS1 PSME4 PCSK6 CHRD LAMA5 EP300 SMAD7	2.87e-05	388	45	8	MP:0006113
MousePheno	lethality throughout fetal growth and development, incomplete penetrance	GJA1 FRAS1 TRAF2 PCSK6 CHRD EP300	5.07e-05	208	45	6	MP:0011109
MousePheno	lethality throughout fetal growth and development	GJA1 FRAS1 TRAF2 PCSK6 CHRD LAMA5 NTN1 EP300	6.46e-05	435	45	8	MP:0006208
MousePheno	abnormal interventricular septum morphology	GJA1 FRAS1 PSME4 PCSK6 LAMA5 EP300 SMAD7	1.01e-04	342	45	7	MP:0000281
Domain	ZF_RING_1	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B NFXL1 RNF216 LONRF3 TRIM40 LONRF2 TRIM3	9.00e-13	291	52	13	PS00518
Domain	ZF_RING_2	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B NFXL1 RNF216 LONRF3 TRIM40 LONRF2 TRIM3	1.22e-12	298	52	13	PS50089
Domain	Znf_RING	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B NFXL1 LONRF3 TRIM40 LONRF2 TRIM3	7.22e-11	326	52	12	IPR001841
Domain	RING	TRIM33 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B LONRF3 TRIM40 LONRF2 TRIM3	6.13e-10	305	52	11	SM00184
Domain	-	TRIM33 TRIM66 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B LONRF3 TRIM40 LONRF2 TRIM3	2.78e-09	449	52	12	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRIM33 TRIM66 TRAF2 TRAF3 RNF19A SH3RF2 RNF112 RNF19B LONRF3 TRIM40 LONRF2 TRIM3	3.56e-09	459	52	12	IPR013083
Domain	Znf_RING_CS	TRIM33 TRAF2 TRAF3 SH3RF2 LONRF3 TRIM40 LONRF2 TRIM3	1.54e-08	163	52	8	IPR017907
Domain	Znf_C3HC4_RING-type	TRAF2 SH3RF2 RNF112 LONRF3 TRIM40 LONRF2 TRIM3	4.69e-07	172	52	7	IPR018957
Domain	Znf-RING_LisH	TRIM33 SH3RF2 LONRF2 TRIM3	2.33e-06	34	52	4	IPR027370
Domain	zf-RING_UBOX	TRIM33 SH3RF2 LONRF2 TRIM3	2.33e-06	34	52	4	PF13445
Domain	zf-C3HC4	TRAF2 SH3RF2 RNF112 LONRF3 TRIM40 LONRF2 TRIM3	2.67e-06	223	52	7	PF00097
Domain	IBR	RNF19A RNF19B RNF216	7.25e-06	14	52	3	SM00647
Domain	Bbox_C	TRIM33 TRIM66 TRIM3	9.05e-06	15	52	3	IPR003649
Domain	IBR_dom	RNF19A RNF19B RNF216	9.05e-06	15	52	3	IPR002867
Domain	BBC	TRIM33 TRIM66 TRIM3	9.05e-06	15	52	3	SM00502
Domain	-	TRIM33 TRIM66 TRIM40 TRIM3	4.52e-05	71	52	4	4.10.45.10
Domain	Neurhyp_horm	LONRF3 LONRF2	4.55e-05	4	52	2	IPR000981
Domain	VWC	FRAS1 CHRD VWCE	6.35e-05	28	52	3	PF00093
Domain	Growth_fac_rcpt_	FRAS1 IGFBP4 PCSK6 LAMA5 VWCE	7.22e-05	156	52	5	IPR009030
Domain	ZF_BBOX	TRIM33 TRIM66 TRIM40 TRIM3	7.23e-05	80	52	4	PS50119
Domain	Znf_B-box	TRIM33 TRIM66 TRIM40 TRIM3	7.59e-05	81	52	4	IPR000315
Domain	LON	LONRF3 LONRF2	1.13e-04	6	52	2	SM00464
Domain	TNF_rcpt--assoc_TRAF	TRAF2 TRAF3	1.13e-04	6	52	2	IPR012227
Domain	LON_N	LONRF3 LONRF2	1.13e-04	6	52	2	PS51787
Domain	LON_substr-bd_dom	LONRF3 LONRF2	1.13e-04	6	52	2	IPR003111
Domain	LON_substr_bdg	LONRF3 LONRF2	1.13e-04	6	52	2	PF02190
Domain	VWFC_1	FRAS1 CHRD VWCE	1.36e-04	36	52	3	PS01208
Domain	BROMODOMAIN_1	TRIM33 TRIM66 EP300	1.48e-04	37	52	3	PS00633
Domain	VWC	FRAS1 CHRD VWCE	1.60e-04	38	52	3	SM00214
Domain	Bromodomain	TRIM33 TRIM66 EP300	1.60e-04	38	52	3	PF00439
Domain	VWFC_2	FRAS1 CHRD VWCE	1.60e-04	38	52	3	PS50184
Domain	BROMODOMAIN_2	TRIM33 TRIM66 EP300	2.01e-04	41	52	3	PS50014
Domain	zf-TRAF	TRAF2 TRAF3	2.11e-04	8	52	2	PF02176
Domain	BROMO	TRIM33 TRIM66 EP300	2.16e-04	42	52	3	SM00297
Domain	Bromodomain	TRIM33 TRIM66 EP300	2.16e-04	42	52	3	IPR001487
Domain	-	TRIM33 TRIM66 EP300	2.16e-04	42	52	3	1.20.920.10
Domain	VWF_dom	FRAS1 CHRD VWCE	2.16e-04	42	52	3	IPR001007
Domain	E3_UB_ligase_RBR	RNF19A RNF19B	3.37e-04	10	52	2	IPR031127
Domain	EGF	SNED1 FRAS1 PCSK6 LAMA5 VWCE	4.85e-04	235	52	5	SM00181
Domain	MATH/TRAF_dom	TRAF2 TRAF3	4.93e-04	12	52	2	IPR002083
Domain	MATH	TRAF2 TRAF3	4.93e-04	12	52	2	PS50144
Domain	MATH	TRAF2 TRAF3	4.93e-04	12	52	2	SM00061
Domain	Znf_TRAF	TRAF2 TRAF3	4.93e-04	12	52	2	IPR001293
Domain	MATH	TRAF2 TRAF3	4.93e-04	12	52	2	PF00917
Domain	ZF_TRAF	TRAF2 TRAF3	5.82e-04	13	52	2	PS50145
Domain	EGF-like_dom	SNED1 FRAS1 PCSK6 LAMA5 VWCE	6.31e-04	249	52	5	IPR000742
Domain	IBR	RNF19A RNF19B	6.77e-04	14	52	2	PF01485
Domain	-	TRAF2 TRAF3	6.77e-04	14	52	2	2.60.210.10
Domain	EGF_1	SNED1 LAMA5 NTN1 VWCE ITGB7	7.02e-04	255	52	5	PS00022
Domain	EGF-like_CS	SNED1 LAMA5 NTN1 VWCE ITGB7	7.80e-04	261	52	5	IPR013032
Domain	Zinc_finger_PHD-type_CS	TRIM33 TRIM66 NFXL1	7.87e-04	65	52	3	IPR019786
Domain	EGF_2	SNED1 LAMA5 NTN1 VWCE ITGB7	8.35e-04	265	52	5	PS01186
Domain	Laminin_N	LAMA5 NTN1	8.90e-04	16	52	2	IPR008211
Domain	LAMININ_NTER	LAMA5 NTN1	8.90e-04	16	52	2	PS51117
Domain	Laminin_N	LAMA5 NTN1	8.90e-04	16	52	2	PF00055
Domain	LamNT	LAMA5 NTN1	8.90e-04	16	52	2	SM00136
Domain	BBOX	TRIM33 TRIM66 TRIM3	9.37e-04	69	52	3	SM00336
Domain	zf-B_box	TRIM33 TRIM66 TRIM3	1.06e-03	72	52	3	PF00643
Domain	Furin_repeat	FRAS1 PCSK6	1.13e-03	18	52	2	IPR006212
Domain	FU	FRAS1 PCSK6	1.13e-03	18	52	2	SM00261
Domain	VWC_out	FRAS1 VWCE	1.26e-03	19	52	2	SM00215
Domain	PUA-like_domain	LONRF3 LONRF2	1.26e-03	19	52	2	IPR015947
Domain	PRAME_family	PRAMEF5 PRAMEF6	1.26e-03	19	52	2	IPR026271
Domain	TRAF-like	TRAF2 TRAF3	2.02e-03	24	52	2	IPR008974
Domain	Galactose-bd-like	PCSK6 LAMA5 NTN1	2.28e-03	94	52	3	IPR008979
Domain	-	ZNF668 ZNF777 ZBTB48 ZNF827 EGR4 ZNF629 ZNF831	2.63e-03	679	52	7	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF668 ZNF777 ZBTB48 ZNF827 EGR4 ZNF629 ZNF831	2.97e-03	694	52	7	IPR013087
Domain	EGF_LAM_2	LAMA5 NTN1	3.15e-03	30	52	2	PS50027
Domain	EGF_LAM_1	LAMA5 NTN1	3.15e-03	30	52	2	PS01248
Domain	GPS	ADGRG2 ADGRB2	4.03e-03	34	52	2	SM00303
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	TRAF2 TRAF3 RNF216 EP300	3.38e-05	82	32	4	M1002
Pathway	KEGG_TGF_BETA_SIGNALING_PATHWAY	CHRD ROCK1 EP300 SMAD7	4.08e-05	86	32	4	M2642
Pathway	KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY	TRAF2 TRAF3	1.39e-04	8	32	2	M47587
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	TRAF3 EP300	1.78e-04	9	32	2	M47451
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	TRIM33 EP300 SMAD7	2.05e-04	51	32	3	M665
Pathway	REACTOME_DEUBIQUITINATION	TRAF2 TRAF3 PSME4 EP300 SMAD7	2.85e-04	262	32	5	MM15286
Pathway	BIOCARTA_TALL1_PATHWAY	TRAF2 TRAF3	3.83e-04	13	32	2	MM1507
Pathway	WP_SARSCOV2_INNATE_IMMUNITY_EVASION_AND_CELLSPECIFIC_IMMUNE_RESPONSE	TRAF2 TRAF3 EP300	4.41e-04	66	32	3	M40067
Pathway	BIOCARTA_TALL1_PATHWAY	TRAF2 TRAF3	5.15e-04	15	32	2	M12985
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	TRAF3 EP300	5.15e-04	15	32	2	M953
Pathway	REACTOME_DEUBIQUITINATION	TRAF2 TRAF3 PSME4 EP300 SMAD7	5.22e-04	299	32	5	M27574
Pathway	BIOCARTA_TNFR2_PATHWAY	TRAF2 TRAF3	6.65e-04	17	32	2	M10082
Pathway	REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY	TRAF2 TRAF3	6.65e-04	17	32	2	M27561
Pathway	BIOCARTA_TGFB_PATHWAY	EP300 SMAD7	6.65e-04	17	32	2	MM1509
Pathway	BIOCARTA_TNFR2_PATHWAY	TRAF2 TRAF3	6.65e-04	17	32	2	MM1517
Pathway	REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY	TRAF2 TRAF3	7.47e-04	18	32	2	MM15275
Pathway	BIOCARTA_TGFB_PATHWAY	EP300 SMAD7	8.33e-04	19	32	2	M18933
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	TRAF2 TRAF3 LAMA5	8.94e-04	84	32	3	M3228
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	TRAF2 TRAF3 ZBTB48 LONRF2 KLHL18 TRIM3	6.89e-08	138	53	6	28786561
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRIM33 TRAF2 RNF19A RNF19B RNF216	3.54e-07	95	53	5	29643511
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TRAF2 TRAF3 ADGRB2 CHRD LAMA5 ALAS1 VWCE TRIM3	2.02e-06	560	53	8	21653829
Pubmed	Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors.	GJA1 P2RX7	2.28e-06	2	53	2	15331634
Pubmed	Unique signaling properties of CTAR1 in LMP1-mediated transformation.	TRAF2 TRAF3	2.28e-06	2	53	2	17626074
Pubmed	Brief Research Report Regional Difference in TRAF2 and TRAF3 Gene Mutations in Colon Cancers.	TRAF2 TRAF3	2.28e-06	2	53	2	34257589
Pubmed	SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence.	TRAF2 TRAF3	2.28e-06	2	53	2	38005906
Pubmed	Functional analysis of corin protein domains required for PCSK6-mediated activation.	PCSK6 CORIN	2.28e-06	2	53	2	29180304
Pubmed	Roles of TRAF2 and TRAF3 in Epstein-Barr virus latent membrane protein 1-induced alternative NF-kappaB activation.	TRAF2 TRAF3	2.28e-06	2	53	2	20585848
Pubmed	PCSK6-mediated corin activation is essential for normal blood pressure.	PCSK6 CORIN	2.28e-06	2	53	2	26259032
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDR2L TBC1D16 FRAS1 PSME4 SLC45A3 ZNF827 ADGRB2 LAMA5 EP300 SMAD7	5.67e-06	1105	53	10	35748872
Pubmed	Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.	TRIM33 PCSK6 CHRD	6.61e-06	24	53	3	20573697
Pubmed	RhoA/ROCK Regulates Prion Pathogenesis by Controlling Connexin 43 Activity.	GJA1 ROCK1	6.83e-06	3	53	2	32070020
Pubmed	Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1.	TRAF2 TRAF3	6.83e-06	3	53	2	19667091
Pubmed	TRAF2 regulates peripheral CD8(+) T-cell and NKT-cell homeostasis by modulating sensitivity to IL-15.	TRAF2 TRAF3	6.83e-06	3	53	2	25931426
Pubmed	USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation.	TRAF2 TRAF3	6.83e-06	3	53	2	30038267
Pubmed	TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.	TRAF2 TRAF3	6.83e-06	3	53	2	19228877
Pubmed	Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3.	TRAF2 TRAF3	6.83e-06	3	53	2	9151858
Pubmed	Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"?	GJA1 P2RX7	6.83e-06	3	53	2	22797941
Pubmed	The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling.	TRAF2 TRAF3	6.83e-06	3	53	2	16311516
Pubmed	Control of Smad7 stability by competition between acetylation and ubiquitination.	EP300 SMAD7	6.83e-06	3	53	2	12408818
Pubmed	TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-κB1 Activation.	TRAF2 TRAF3	6.83e-06	3	53	2	30341187
Pubmed	Silencing of URG11 expression inhibits the proliferation and epithelial‑mesenchymal transition in benign prostatic hyperplasia cells via the RhoA/ROCK1 pathway.	ROCK1 VWCE	6.83e-06	3	53	2	29749520
Pubmed	Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.	TRAF2 TRAF3	6.83e-06	3	53	2	18997792
Pubmed	TRAF2 decrease promotes the TGF-β-mTORC1 signal in MAFLD-HCC through enhancing AXIN1-mediated Smad7 degradation.	TRAF2 SMAD7	6.83e-06	3	53	2	38363556
Pubmed	Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation.	GJA1 P2RX7	6.83e-06	3	53	2	32103010
Pubmed	Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation.	TRAF2 TRAF3	6.83e-06	3	53	2	10352240
Pubmed	Characterization of the latent membrane protein 1 signaling complex of Epstein-Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementation.	TRAF2 TRAF3	6.83e-06	3	53	2	21864338
Pubmed	Human 4-1BB (CD137) signals are mediated by TRAF2 and activate nuclear factor-kappa B.	TRAF2 TRAF3	1.36e-05	4	53	2	9464265
Pubmed	Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC.	TRAF2 TRAF3	1.36e-05	4	53	2	31034780
Pubmed	TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase.	TRAF2 TRAF3	1.36e-05	4	53	2	10903733
Pubmed	TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.	TRAF2 TRAF3	1.36e-05	4	53	2	15708970
Pubmed	TRIM40 interacts with ROCK1 directly and inhibits colorectal cancer cell proliferation through the c-Myc/p21 axis.	ROCK1 TRIM40	1.36e-05	4	53	2	39357549
Pubmed	Analyses of TGF-beta1-inducible Ig germ-line gamma2b promoter activity: involvement of Smads and NF-kappaB.	EP300 SMAD7	1.36e-05	4	53	2	19266485
Pubmed	TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation.	TRAF2 TRAF3	1.36e-05	4	53	2	15208311
Pubmed	Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor of NF-kappa B activation.	TRAF2 TRAF3	1.36e-05	4	53	2	15944293
Pubmed	Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta.	ITGB7 SMAD7	1.36e-05	4	53	2	11934870
Pubmed	A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.	TRAF2 TRAF3	1.36e-05	4	53	2	21041452
Pubmed	Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells.	TRAF2 TRAF3	1.36e-05	4	53	2	25051892
Pubmed	Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene.	ZBTB48 EP300	1.36e-05	4	53	2	24382891
Pubmed	NF-kappaB activation in CD27 signaling: involvement of TNF receptor-associated factors in its signaling and identification of functional region of CD27.	TRAF2 TRAF3	1.36e-05	4	53	2	9794406
Pubmed	CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.	TRAF2 TRAF3	1.36e-05	4	53	2	9582383
Pubmed	The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching.	TRAF2 TRAF3	1.36e-05	4	53	2	12354380
Pubmed	Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response.	TRAF3 RNF216	1.36e-05	4	53	2	27026194
Pubmed	Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation.	TRAF2 TRAF3	1.36e-05	4	53	2	23603814
Pubmed	CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins.	TRAF2 TRAF3	1.36e-05	4	53	2	8662842
Pubmed	Downstream regulator TANK binds to the CD40 recognition site on TRAF3.	TRAF2 TRAF3	1.36e-05	4	53	2	12005438
Pubmed	TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells.	TRAF2 TRAF3	1.36e-05	4	53	2	16260598
Pubmed	The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK.	TRAF2 TRAF3	1.36e-05	4	53	2	20818435
Pubmed	Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.	TRAF2 TRAF3	1.36e-05	4	53	2	26122662
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 PSME4 PCSK6 LAMA5	1.69e-05	100	53	4	25807483
Pubmed	RACK1 attenuates RLR antiviral signaling by targeting VISA-TRAF complexes.	TRAF2 TRAF3	2.27e-05	5	53	2	30527812
Pubmed	NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation.	TRAF2 TRAF3	2.27e-05	5	53	2	25072696
Pubmed	The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation.	TRAF3 RNF216	2.27e-05	5	53	2	19893624
Pubmed	SOX9 negatively regulates the RLR antiviral signaling by targeting MAVS.	TRAF2 TRAF3	2.27e-05	5	53	2	35103914
Pubmed	Mapping modifiers affecting muscularity of the myostatin mutant (Mstn(Cmpt-dl1Abc)) compact mouse.	PCSK6 CHRD	2.27e-05	5	53	2	14504233
Pubmed	TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.	TRAF2 TRAF3	2.27e-05	5	53	2	17332487
Pubmed	Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.	TRAF2 TRAF3	2.27e-05	5	53	2	10037686
Pubmed	Comparison of the peptide binding preferences of three closely related TRAF paralogs: TRAF2, TRAF3, and TRAF5.	TRAF2 TRAF3	2.27e-05	5	53	2	26779844
Pubmed	Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation.	TRAF2 TRAF3	2.27e-05	5	53	2	12169272
Pubmed	RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.	TRAF2 TRAF3	2.27e-05	5	53	2	29661858
Pubmed	P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid.	P2RX7 ROCK1	2.27e-05	5	53	2	17135244
Pubmed	Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.	TRAF2 TRAF3	2.27e-05	5	53	2	18997794
Pubmed	Nuclear TRAF3 is a negative regulator of CREB in B cells.	TRAF2 TRAF3	2.27e-05	5	53	2	26755589
Pubmed	Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1).	TRAF2 TRAF3	2.27e-05	5	53	2	10523862
Pubmed	Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40.	TRAF2 TRAF3	2.27e-05	5	53	2	9990007
Pubmed	Mitochondrial DUT-M potentiates RLR-mediated antiviral signaling by enhancing VISA and TRAF2 association.	TRAF2 TRAF3	2.27e-05	5	53	2	33582548
Pubmed	Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation.	TRAF2 TRAF3	2.27e-05	5	53	2	29903906
Pubmed	Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development.	TRAF2 TRAF3	2.27e-05	5	53	2	9507120
Pubmed	TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death.	TRAF2 TRAF3	2.27e-05	5	53	2	10809768
Pubmed	Expression of TNF-receptor-associated factor genes in murine tooth development.	TRAF2 TRAF3	2.27e-05	5	53	2	12711536
Pubmed	The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators.	TRAF2 TRAF3	3.40e-05	6	53	2	11384837
Pubmed	The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways.	TRAF2 TRAF3	3.40e-05	6	53	2	10837247
Pubmed	SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response.	TRAF2 TRAF3	3.40e-05	6	53	2	33707416
Pubmed	Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling.	TRAF2 TRAF3	3.40e-05	6	53	2	12958312
Pubmed	TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.	TRAF2 TRAF3	3.40e-05	6	53	2	18313334
Pubmed	Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.	TRAF2 TRAF3	3.40e-05	6	53	2	21041727
Pubmed	Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.	TRAF2 TRAF3	3.40e-05	6	53	2	10097072
Pubmed	Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).	TRAF2 TRAF3	3.40e-05	6	53	2	11435475
Pubmed	Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.	TRAF2 TRAF3	3.40e-05	6	53	2	19937093
Pubmed	Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase.	TRAF2 TRAF3	3.40e-05	6	53	2	10025951
Pubmed	Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation.	TRAF2 TRAF3	3.40e-05	6	53	2	9488716
Pubmed	Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.	TRAF2 TRAF3	3.40e-05	6	53	2	15084608
Pubmed	p300 modulates HIV-1 gp120-induced apoptosis in human proximal tubular cells: associated with alteration of TGF-beta and Smad signaling.	EP300 SMAD7	3.40e-05	6	53	2	16179804
Pubmed	TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.	TRAF2 TRAF3	3.40e-05	6	53	2	8565075
Pubmed	N4BP3 Regulates RIG-I-Like Receptor Antiviral Signaling Positively by Targeting Mitochondrial Antiviral Signaling Protein.	TRAF2 TRAF3	3.40e-05	6	53	2	34880843
Pubmed	Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.	TRAF2 TRAF3	3.40e-05	6	53	2	9275204
Pubmed	Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily.	TRAF2 TRAF3	3.40e-05	6	53	2	9168896
Pubmed	BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.	TRAF2 TRAF3	3.40e-05	6	53	2	20138174
Pubmed	A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.	TRAF2 TRAF3	3.40e-05	6	53	2	27135603
Pubmed	The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily.	TRAF2 TRAF3	3.40e-05	6	53	2	9852070
Pubmed	TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation.	TRAF2 TRAF3	3.40e-05	6	53	2	15383523
Pubmed	Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.	TRAF2 TRAF3	3.40e-05	6	53	2	14517219
Pubmed	Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-κB pathway in TNF stimulation.	TRAF2 TRAF3	3.40e-05	6	53	2	23543740
Pubmed	The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells.	TRAF2 TRAF3	3.40e-05	6	53	2	10799510
Pubmed	Tumor necrosis factor receptor-associated factors (TRAFs).	TRAF2 TRAF3	3.40e-05	6	53	2	11607847
Pubmed	I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.	TRAF2 TRAF3	3.40e-05	6	53	2	8710854
Pubmed	BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS.	TRAF2 TRAF3	3.40e-05	6	53	2	36045679
Pubmed	A20 undermines alternative NF-κB activity and expression of anti-apoptotic genes in Helicobacter pylori infection.	TRAF2 TRAF3	3.40e-05	6	53	2	35089437
Pubmed	TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.	TRAF2 TRAF3	3.40e-05	6	53	2	8612133
Interaction	NOTCH2 interactions	GJA1 TRIM66 ZNF668 ZNF777 IGFBP4 ZBTB48 ZNF629 NTN1 C9orf163	1.20e-06	423	52	9	int:NOTCH2
Cytoband	Ensembl 112 genes in cytogenetic band chr4p12	NFXL1 CORIN	4.18e-04	26	53	2	chr4p12
GeneFamily	Ring finger proteins	TRIM33 TRAF2 RNF19A SH3RF2 RNF112 RNF19B RNF216 LONRF3 TRIM40 LONRF2 TRIM3	3.09e-11	275	43	11	58
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM33 TRIM66 TRIM40 TRIM3	7.54e-05	95	43	4	59
GeneFamily	TNF receptor associated factors	TRAF2 TRAF3	1.15e-04	7	43	2	1056
GeneFamily	PRAME family	PRAMEF5 PRAMEF6	1.48e-03	24	43	2	686
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF668 ZNF777 ZBTB48 ZNF827 EGR4 ZNF629	6.69e-03	718	43	6	28
GeneFamily	PHD finger proteins	TRIM33 TRIM66	1.94e-02	90	43	2	88
Coexpression	NABA_ECM_GLYCOPROTEINS	SNED1 FRAS1 IGFBP4 LAMA5 NTN1 VWCE	2.39e-06	191	53	6	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	SNED1 FRAS1 IGFBP4 LAMA5 NTN1 VWCE	2.78e-06	196	53	6	M3008
Coexpression	GSE26351_UNSTIM_VS_WNT_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP	ZNF777 TRAF2 IGFBP4 ALAS1 KLHL18 SMAD7	3.12e-06	200	53	6	M8482
Coexpression	GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP	TRIM33 ZNF777 TRAF3 SLC45A3 RNF112 PLEKHM3	3.12e-06	200	53	6	M7366
Coexpression	NABA_CORE_MATRISOME	SNED1 FRAS1 IGFBP4 LAMA5 NTN1 VWCE	1.73e-05	270	53	6	MM17057
Coexpression	NABA_CORE_MATRISOME	SNED1 FRAS1 IGFBP4 LAMA5 NTN1 VWCE	1.92e-05	275	53	6	M5884
Coexpression	GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP	DZANK1 TRAF2 ZBTB48 ZNF827 ADGRB2	5.12e-05	199	53	5	M313
Coexpression	GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP	TRIM33 TRAF3 RNF216 ALAS1 PLEKHM3	5.24e-05	200	53	5	M8500
Coexpression	SMID_BREAST_CANCER_BASAL_DN	SNED1 GJA1 DZANK1 IGFBP4 PCSK6 ADGRB2 CHRD TRIM3	7.55e-05	699	53	8	M4960
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	7.91e-08	182	53	6	0cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	7.91e-08	182	53	6	2cc434e46985c66fc36de05344a67aa96d90abc9
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	7.91e-08	182	53	6	3e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.78e-07	124	53	5	4b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6 NTN1	1.85e-06	171	53	5	686f95892c3909973c66c9a27159a070a068f175
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6 NTN1	1.85e-06	171	53	5	f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCell	PND14-Endothelial-Endothelial_lymphatic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6 NTN1	1.85e-06	171	53	5	d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6 NTN1	1.85e-06	171	53	5	fbf8e9db00573adcada4b25730e191417b7c9999
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	SNED1 GJA1 SLC45A3 PCSK6 NTN1	1.91e-06	172	53	5	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.13e-06	176	53	5	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.13e-06	176	53	5	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	P28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNED1 GJA1 SLC45A3 PCSK6 NTN1	2.19e-06	177	53	5	e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GJA1 IGFBP4 RNF112 ZDHHC14 NTN1	2.19e-06	177	53	5	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	P28-Endothelial-lymphatic_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNED1 GJA1 SLC45A3 PCSK6 NTN1	2.19e-06	177	53	5	6e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 GJA1 SLC45A3 PCSK6 NTN1	2.72e-06	185	53	5	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.72e-06	185	53	5	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 GJA1 SLC45A3 PCSK6 NTN1	2.72e-06	185	53	5	64791056cdbb739136dbef08f4b16e2b5427faad
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.72e-06	185	53	5	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.80e-06	186	53	5	f23f21781a758541f59c06efa7739d26a03fb478
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	2.80e-06	186	53	5	0de87109da9324c597fadf2eb782f0f158afe832
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CDR2L GJA1 FRAS1 SH3RF2 LAMA5	2.87e-06	187	53	5	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 GJA1 SLC45A3 PCSK6 NTN1	2.95e-06	188	53	5	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 GJA1 SLC45A3 PCSK6 NTN1	2.95e-06	188	53	5	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SNED1 GJA1 SLC45A3 PCSK6 NTN1	3.10e-06	190	53	5	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	3.18e-06	191	53	5	51cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	3.18e-06	191	53	5	a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 IGFBP4 SLC45A3 PCSK6 NTN1	3.18e-06	191	53	5	38681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCell	Control-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	GJA1 IGFBP4 PCSK6 ZDHHC14 NTN1	3.26e-06	192	53	5	f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCell	Control-Endothelial-Lymphatic\|Control / Disease state, Lineage and Cell class	GJA1 IGFBP4 PCSK6 ZDHHC14 NTN1	3.35e-06	193	53	5	64d19be73e5432d491436a01da5de5c926b615a9
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA1 IGFBP4 PCSK6 ZDHHC14 NTN1	3.43e-06	194	53	5	f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA1 IGFBP4 PCSK6 ZDHHC14 NTN1	3.43e-06	194	53	5	5d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA1 IGFBP4 PCSK6 ZDHHC14 NTN1	3.43e-06	194	53	5	3b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCell	COPD-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	SNED1 IGFBP4 PCSK6 LONRF3 LONRF2	3.61e-06	196	53	5	4930eeb303d174c28fd91021723e26fdf1af9170
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 EGR4 CHRD ZNF831	9.36e-06	111	53	4	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2L TBC1D16 ZNF777 NTN1	1.32e-05	121	53	4	e82c9e10b98c8d7ad828cf8ac19a2342014be2ba
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|367C / Donor, Lineage, Cell class and subclass (all cells)	EGR4 PCSK6 PLEKHM3 ITGB7	1.80e-05	131	53	4	cc5b5afab8622e98f673fa116a226d930c295327
ToppCell	metastatic_Brain-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	FRAS1 IGFBP4 ZNF629 CORIN	2.21e-05	138	53	4	b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCell	tumor_Lung-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	FRAS1 ZNF629 NFXL1 ZNF831	2.75e-05	146	53	4	8b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCell	Globus_pallidus-Neuronal-Excitatory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FRAS1 EGR4 SH3RF2 ZNF831	3.94e-05	160	53	4	f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 SLC45A3 PCSK6 NTN1	4.03e-05	161	53	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 SLC45A3 PCSK6 NTN1	4.03e-05	161	53	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 SLC45A3 PCSK6 NTN1	4.03e-05	161	53	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FRAS1 EGR4 SH3RF2 ZNF831	4.03e-05	161	53	4	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 SLC45A3 PCSK6 NTN1	4.13e-05	162	53	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6	4.34e-05	164	53	4	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6	4.34e-05	164	53	4	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6	4.34e-05	164	53	4	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 GJA1 SLC45A3 PCSK6	4.34e-05	164	53	4	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP4 SLC45A3 PCSK6 NTN1	4.44e-05	165	53	4	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP4 SLC45A3 PCSK6 NTN1	4.44e-05	165	53	4	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP4 SLC45A3 PCSK6 NTN1	4.44e-05	165	53	4	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP4 SLC45A3 PCSK6 NTN1	4.44e-05	165	53	4	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 SLC45A3 PCSK6 NTN1	4.44e-05	165	53	4	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	CDR2L FRAS1 IGFBP4 EGR4	4.55e-05	166	53	4	ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EGR4 RNF112 CHRD ZNF831	4.76e-05	168	53	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC45A3 RNF112 PCSK6 NTN1	4.87e-05	169	53	4	f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC45A3 RNF112 PCSK6 NTN1	4.99e-05	170	53	4	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC45A3 RNF112 PCSK6 NTN1	4.99e-05	170	53	4	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC45A3 RNF112 PCSK6 NTN1	4.99e-05	170	53	4	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 SLC45A3 PCSK6 NTN1	5.22e-05	172	53	4	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 SLC45A3 PCSK6 NTN1	5.22e-05	172	53	4	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	Mesenchymal_cells-Osteo-CAR\|Mesenchymal_cells / Lineage and Cell class	GJA1 IGFBP4 PORCN PLEKHM3	5.46e-05	174	53	4	430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 SLC45A3 PCSK6 NTN1	5.58e-05	175	53	4	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 SLC45A3 PCSK6 NTN1	5.58e-05	175	53	4	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GJA1 SLC45A3 PCSK6 NTN1	5.58e-05	175	53	4	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 EGR4 RNF112 ZNF831	5.58e-05	175	53	4	21f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 EGR4 RNF112 ZNF831	5.58e-05	175	53	4	ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GJA1 SLC45A3 PCSK6 NTN1	5.58e-05	175	53	4	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RX7 LAMA5 KLHL18 ITGB7	6.36e-05	181	53	4	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	BAL-Control-cDC_8\|Control / Compartment, Disease Groups and Clusters	ZNF777 IGFBP4 PORCN LONRF3	6.36e-05	181	53	4	f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 P2RX7 PCSK6 NTN1	6.36e-05	181	53	4	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 SLC45A3 SH3RF2 TRIM3	6.50e-05	182	53	4	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 SLC45A3 SH3RF2 TRIM3	6.50e-05	182	53	4	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	EGR4 RNF112 ADGRB2 ZNF831	6.78e-05	184	53	4	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GJA1 SLC45A3 ZDHHC14 ZNF831	6.92e-05	185	53	4	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGFBP4 PCSK6 CHRD NTN1	6.92e-05	185	53	4	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 IGFBP4 SLC45A3 ZNF831	6.92e-05	185	53	4	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 IGFBP4 SLC45A3 ZNF831	7.07e-05	186	53	4	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGFBP4 ADGRG2 PCSK6 NTN1	7.22e-05	187	53	4	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	GJA1 PCSK6 ZDHHC14 NTN1	7.22e-05	187	53	4	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGFBP4 PCSK6 CHRD NTN1	7.37e-05	188	53	4	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	GJA1 PCSK6 ZDHHC14 NTN1	7.37e-05	188	53	4	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GJA1 PCSK6 ZDHHC14 NTN1	7.37e-05	188	53	4	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 IGFBP4 PCSK6 NTN1	7.52e-05	189	53	4	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EGR4 ADGRB2 CHRD ZNF831	7.52e-05	189	53	4	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CDR2L ADGRG2 ADGRB2 NTN1	7.52e-05	189	53	4	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 SLC45A3 PCSK6 NTN1	7.68e-05	190	53	4	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNED1 PCSK6 ZDHHC14 NTN1	7.68e-05	190	53	4	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	IPF-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	GJA1 IGFBP4 PCSK6 ZDHHC14	7.68e-05	190	53	4	ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 SLC45A3 PCSK6 NTN1	7.68e-05	190	53	4	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 SLC45A3 PCSK6 NTN1	7.68e-05	190	53	4	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 PCSK6 ADGRB2 NTN1	7.83e-05	191	53	4	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 GJA1 SLC45A3 PCSK6	7.83e-05	191	53	4	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 GJA1 SLC45A3 PCSK6	7.83e-05	191	53	4	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	IPF-Endothelial-Lymphatic\|IPF / Disease state, Lineage and Cell class	GJA1 IGFBP4 PCSK6 ZDHHC14	7.99e-05	192	53	4	2496edd8f3a41146d418879de9ee2ccc7857431f
Disease	pulmonary hypertension (biomarker_via_orthology)	GJA1 ALAS1 SMAD7	3.43e-04	80	50	3	DOID:6432 (biomarker_via_orthology)
Disease	platelet component distribution width	TRIM33 TRAF2 ZNF629 ZDHHC14 LAMA5 ZNF831	1.68e-03	755	50	6	EFO_0007984
Disease	oral microbiome measurement	FRAS1 TRIM40	2.32e-03	42	50	2	EFO_0801229
Disease	dimethylglycine measurement	PCSK6 ZDHHC14	2.78e-03	46	50	2	EFO_0010476
Disease	lymphocyte count	TBC1D16 FRAS1 TRAF3 PSME4 SLC45A3 RNF19A ZNF831 ITGB7	3.01e-03	1464	50	8	EFO_0004587
Disease	serum non-albumin protein measurement	TBC1D16 TRAF3 LONRF2 TSEN2	3.26e-03	361	50	4	EFO_0004568

Protein segments in the cluster

Peptide	Gene	Start	Entry
PCSEKRCPAFHEMCR	ADGRB2	521	O60241
CTRHDCPVCLPLKNA	EP300	406	Q09472
HTFPCLKELCTSPRC	CDR2L	156	Q86X02
CTLRGRRCHCLPFPK	C9orf163	141	Q8N9P6
IRPMEHCCCSVRIPC	ADGRG2	211	Q8IZP9
CRHNTAGPECDRCKP	NTN1	306	O95631
LIHLDGKCCPECISR	FRAS1	331	Q86XX4
VCEREFKPPCGHKCL	NFXL1	256	Q6ZNB6
PECLHCEEGCSKSRP	NFXL1	696	Q6ZNB6
LKPHSSAECNFCRRP	ALAS1	601	P13196
PGLPHKVCRRCDENC	PCSK6	891	P29122
RHCPRHCPREACANK	FAM205A	1316	Q6ZU69
KCLERCLDHAPHCPL	LONRF2	471	Q1L5Z9
TRCFCPRPHAKAFAC	EGR4	471	Q05215
CRAHVEGPSCDRCKP	LAMA5	746	O15230
FHSECKEKSVPCPRC	PLEKHM3	711	Q6ZWE6
DQCPGCKTPCERHRD	ITGB7	636	P26010
ILSACVLSKRCPPDC	PORCN	371	Q9H237
HRCLEELCCRKKPGA	P2RX7	491	Q99572
ACCTFLRERLHPKNC	KLHL18	126	O94889
TCKRDPCPHQVDCFL	GJA1	186	P17302
IPPCRALCEHSKERC	CORIN	526	Q9Y5Q5
TDFLKCAHCLAPRPS	DZANK1	206	Q9NVP4
REDASPLPHVCCCKQ	TSEN2	211	Q8NCE0
REAEPKLLPCLHSFC	TRIM33	136	Q9UPN9
KLLPCLHSFCLRCLP	TRIM33	141	Q9UPN9
FCCPLCRKPCSEEVL	TRIM40	51	Q6P9F5
APRLLSCPHRSCRDC	RNF19B	131	Q6ZMZ0
FSCPNPHCRKETCRK	RNF216	621	Q9NWF9
HCPPCSEEKLARCRP	IGFBP4	26	P22692
SLSPHCCPCRARLAF	SLC45A3	236	Q96JT2
CEKARPHLCSSGPCR	SNED1	576	Q8TER0
VPHCERDDCSLPLSC	CHRD	906	Q9H2X0
KCRVPCRFHAIGCLE	TRAF2	211	Q12933
RHPKRILFCTDCCPD	PRAMEF6	446	Q5VXH4
PHACPTCAKCFLSRT	ZBTB48	406	P10074
ERKECPPSCHSDIDC	WFDC8	161	Q8IUA0
PDLRHSSEVKRLCCC	SMAD7	166	O15105
CHFEELPCVRPDCKE	TRAF3	141	Q13114
ERTHSGEKPFLCPRC	ZNF668	271	Q96K58
NRCLKHPLARDTPVC	RNF112	156	Q9ULX5
ECPLCLLRHSKDRFP	RNF19A	131	Q9NV58
LPRIPCSLHDLCKLC	TBC1D16	696	Q8TBP0
RHPKRILFCTDCCPD	PRAMEF5	446	Q5TYX0
CEKVRCEAACSHPIP	VWCE	416	Q96DN2
SCKRTDCVDSCPHPI	VWCE	601	Q96DN2
KCCPEESLKLFVPHC	PSME4	636	Q14997
PPALECRRCHVKCHR	ROCK1	1256	Q13464
KIFRPPRASHCSLCD	ZDHHC14	171	Q8IZN3
SHQCPLCPFRCARKD	ZNF827	401	Q17R98
FKAHKELRCPECRTP	SH3RF2	41	Q8TEC5
CPHCGRDCLKPSVLE	ZNF831	146	Q5JPB2
RTHLREDPFKCPVCG	ZNF629	366	Q9UEG4
RERPHACPECGKSFI	ZNF777	746	Q9ULD5
ELLCCDRCPKVFHLS	TRIM66	981	O15016
APRKCCEAVLACPLV	nan	121	Q6ZVH6
CPKVLPCLHTFCERC	TRIM3	31	O75382
PCGHTFCLKCLERCL	LONRF3	481	Q496Y0