Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainVPS10

SORCS3 SORCS1

1.32e-055222IPR006581
DomainSortilin_N

SORCS3 SORCS1

1.32e-055222IPR031778
DomainSortilin_C

SORCS3 SORCS1

1.32e-055222IPR031777
DomainVPS10

SORCS3 SORCS1

1.32e-055222SM00602
DomainSortilin_C

SORCS3 SORCS1

1.32e-055222PF15901
DomainSortilin-Vps10

SORCS3 SORCS1

1.32e-055222PF15902
DomainPKD

SORCS3 SORCS1

2.77e-057222PF00801
DomainSialidases

SORCS3 SORCS1

4.74e-059222IPR011040
DomainPKD

SORCS3 SORCS1

7.24e-0511222PS50093
DomainPKD_dom

SORCS3 SORCS1

7.24e-0511222IPR000601
Domain-

SORCS3 SORCS1

7.24e-05112222.60.40.670
DomainPTPc

PTPRK PTPN13

8.14e-0436222SM00194
DomainTYR_PHOSPHATASE_PTP

PTPRK PTPN13

9.56e-0439222PS50055
DomainPTPase_domain

PTPRK PTPN13

1.06e-0341222IPR000242
DomainY_phosphatase

PTPRK PTPN13

1.06e-0341222PF00102
DomainPTPc_motif

PTPRK PTPN13

2.18e-0359222SM00404
DomainTyr_Pase_cat

PTPRK PTPN13

2.18e-0359222IPR003595
DomainTYR_PHOSPHATASE_1

PTPRK PTPN13

4.56e-0386222PS00383
DomainTYR_PHOSPHATASE_2

PTPRK PTPN13

4.66e-0387222PS50056
DomainTYR_PHOSPHATASE_dom

PTPRK PTPN13

4.66e-0387222IPR000387
Domain-

PTPRK PTPN13

5.20e-03922223.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPRK PTPN13

6.00e-0399222IPR029021
DomainPDZ

MPDZ PTPN13

1.18e-02141222PF00595
DomainPDZ

MPDZ PTPN13

1.30e-02148222SM00228
Domain-

MPDZ PTPN13

1.33e-021502222.30.42.10
DomainPDZ

MPDZ PTPN13

1.35e-02151222PS50106
DomainPDZ

MPDZ PTPN13

1.37e-02152222IPR001478
DomainUbiquitin-rel_dom

PTPN13 RAPGEF4

1.96e-02184222IPR029071
Pubmed

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

SORCS3 SORCS1

3.82e-07222229440124
Pubmed

Identification and characterization of SorCS, a third member of a novel receptor family.

SORCS3 SORCS1

3.82e-07222210600506
Pubmed

Hidden Twins: SorCS Neuroreceptors Form Stable Dimers.

SORCS3 SORCS1

1.15e-06322228827148
Pubmed

Spatiotemporal expression analysis of the growth factor receptor SorCS3.

SORCS3 SORCS1

1.15e-06322224715575
Pubmed

The three sorCS genes are differentially expressed and regulated by synaptic activity.

SORCS3 SORCS1

1.15e-06322215009648
Pubmed

Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.

SORCS3 SORCS1

1.15e-06322231095505
Pubmed

The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

SORCS3 SORCS1

2.29e-06422211499680
Pubmed

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

MPDZ PTPN13

2.29e-06422214516276
Pubmed

Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.

MPDZ PTPN13

2.97e-051322223576434
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

SORCS3 OBI1 TCF4 SORCS1

4.41e-0531822416919269
Pubmed

The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.

MPDZ PTPN13

4.56e-051622218824598
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MECOM OBI1 PTPN13 S100PBP

1.27e-0441822434709266
Pubmed

Turnover of the mTOR inhibitor, DEPTOR, and downstream AKT phosphorylation in multiple myeloma cells, is dependent on ERK1-mediated phosphorylation.

ERAP1 OBI1

5.16e-045322235216969
Pubmed

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

MPDZ PTPN13

5.56e-045522218448421
Cytoband10q23-q25

SORCS3 SORCS1

1.31e-06422210q23-q25
CytobandEnsembl 112 genes in cytogenetic band chr10q25

SORCS3 SORCS1

1.80e-03131222chr10q25
GeneFamilyPDZ domain containing

MPDZ PTPN13

7.80e-031521621220
CoexpressionGSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN

PTPRK MROH9 KLHL35 OBI1 TCF4

5.28e-07196225M4431
CoexpressionPHONG_TNF_RESPONSE_VIA_P38_COMPLETE

PTPRK ERAP1 MECOM TCF4

3.37e-05224224M2500
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_500

ERAP1 MECOM TCF4 AGMO RAPGEF4

4.48e-05417215gudmap_kidney_adult_RenMedVasc_Tie2_500
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#3_top-relative-expression-ranked_500

ERAP1 MECOM RAPGEF4

8.38e-0587213gudmap_kidney_adult_GlomCapSys_Tie2_k3_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

MECOM PTPN13

1.26e-0417212gudmap_kidney_P4_CapMesRenVes_Crym_k4_200
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

DOCK10 PTPRK ERAP1 MECOM PTPN13 RAPGEF4

1.51e-04872216gudmap_kidney_adult_Mesangium_Meis_1000
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SORCS3 TCF4 SORCS1

9.44e-071552243b8def9e8f66511736ea37f259511f7c8b7743af
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SORCS3 TCF4 SORCS1

1.43e-061722247e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM TCF4 AGMO RAPGEF4

1.83e-06183224ff95382cfed592190d0636d2b750328471f82e0d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRK MECOM TCF4 RAPGEF4

2.31e-061942240b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL35 PTPN13 AGMO IL22RA2

2.45e-06197224dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCelldistal-Endothelial-Bronchial_Vessel_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MECOM TCF4 ZNF57 RAPGEF4

2.45e-061972249fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL35 PTPN13 AGMO IL22RA2

2.45e-06197224ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

DOCK10 MROH9 TCF4 PTAR1

2.50e-06198224d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPRK MECOM TCF4 PTPN13

2.55e-061992243d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MPDZ MECOM TCF4 RAPGEF4

2.60e-06200224dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK SORCS3 RAPGEF4 SORCS1

2.60e-062002241a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-062002244fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-06200224f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-06200224cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

DOCK10 KLHL35 OBI1 TCF4

2.60e-06200224332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK SORCS3 RAPGEF4 SORCS1

2.60e-062002246f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK SORCS3 RAPGEF4 SORCS1

2.60e-0620022486705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK SORCS3 RAPGEF4 SORCS1

2.60e-06200224db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-06200224310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-06200224c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

MROH9 SORCS3 RAPGEF4 SORCS1

2.60e-06200224961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 TMEM132E SORCS1

2.81e-051212237f2057367777c6c92f596054cbc5fe567d079fbc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 TMEM132E SORCS1

3.03e-05124223690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 TMEM132E SORCS1

3.49e-051302238bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 TMEM132E SORCS1

3.49e-0513022360e28d452d0e2af768459ba8dbe998117c94a251
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MPDZ SORCS3 SORCS1

4.26e-051392239e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SORCS3 TCF4

4.73e-051442237de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SORCS3 TCF4

5.23e-0514922310ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 TCF4 SORCS1

5.23e-0514922398ae408d2d0347865875ff8bbd89d359decea526
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL35 PTAR1 S100PBP

5.34e-05150223c2c51a3230c978e2fdb1b3ae14193d4014431b25
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SORCS3 TMEM132E TCF4

5.89e-05155223105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SORCS3 TCF4

5.89e-0515522399e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MPDZ TMEM132E RAPGEF4

6.11e-05157223516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SORCS3 TMEM132E TCF4

6.35e-051592237f29f9dcf25ffa1822b137c571e9ac16defc6292
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

6.35e-051592238680b054622f573a82b1625fb93c2d5db81d1034
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 TCF4 SORCS1

6.83e-05163223ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 MPDZ TMEM132E

6.83e-051632238d17f44faf0549fe71a9a45f811f50d767275414
ToppCell390C-Lymphocytic-ILC|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM132E OBI1 PTAR1

6.96e-05164223b0fc63b72162b5cc4d1e0a271a12f3d3ab29398f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

7.21e-05166223c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 TCF4 SORCS1

7.34e-051672231c1b4722c6c0eff85a9b32ca7b4e281caebf63b0
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

SORCS3 PTPN13 SORCS1

7.61e-05169223a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

7.74e-05170223269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

7.74e-05170223a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 TCF4 SORCS1

7.88e-05171223f9ae7964a3740f559431125c17c660549798cccc
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTPRK MECOM AGMO

8.15e-05173223ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

SORCS3 PTPN13 SORCS1

8.15e-051732236fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PTPRK MECOM AGMO

8.29e-05174223110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MECOM TCF4 IL22RA2

8.29e-0517422318ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 TCF4 SORCS1

8.29e-05174223a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCellASK452-Epithelial-Secretory|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZNF57 PTPN13 SORCS1

8.58e-05176223dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL35 MECOM TCF4

8.58e-0517622377516048aefbe1f48e825052756df0c310c1c486
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL35 MECOM TCF4

8.58e-0517622396779273b94345250cf53ba671203345b43d9e00
ToppCellIIH-mDC1-|IIH / Condition, Cell_class and T cell subcluster

TMEM132E AGMO RAPGEF4

8.58e-05176223bb80a3e595d071f6cc8b042984b8d9490e377eef
ToppCellIIH-mDC1|IIH / Condition, Cell_class and T cell subcluster

TMEM132E AGMO RAPGEF4

8.58e-05176223a75dc132a1061006fd1cb305bd314784fca07ea6
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPDZ TCF4 RAPGEF4

8.72e-0517722316197068260fc062bf8b730a51a199887ea580b9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

8.87e-05178223f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

9.17e-05180223198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 MECOM PTPN13

9.17e-05180223023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

SORCS3 PTPN13 SORCS1

9.17e-051802235842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM PTPN13 AGMO

9.32e-05181223aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

SORCS3 PTPN13 SORCS1

9.32e-051812237d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

9.32e-05181223c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

9.47e-05182223759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK RAPGEF4 SORCS1

9.63e-05183223c7e94fe3e7669db9304b249979fef7a69c30a143
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

9.63e-051832236847c1252d6bb105524f812658112517fd351eab
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 RAPGEF4 SORCS1

9.79e-051842239cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

9.79e-05184223369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

9.79e-05184223102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

MECOM TCF4 RAPGEF4

9.79e-051842230f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

9.94e-05185223673f0c688ae6984bc8027df2da335787924f4137
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

MECOM TCF4 RAPGEF4

9.94e-05185223f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

9.94e-0518522398b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

SORCS3 TCF4 RAPGEF4

9.94e-05185223ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM TCF4 AGMO

9.94e-0518522362cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

9.94e-05185223563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

9.94e-05185223cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM PTPN13 AGMO

9.94e-05185223d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

1.01e-041862236a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

1.01e-041862239798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

1.01e-041862233006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

1.03e-0418722381cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

1.03e-041872238407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

MECOM TCF4 RAPGEF4

1.03e-041872232d20193a6cacdfa4877457c97b0077408942186c
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLHL35 MECOM TCF4

1.04e-0418822359f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

MECOM TCF4 RAPGEF4

1.04e-04188223eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

1.04e-04188223707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRK MECOM PTPN13

1.04e-04188223c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF679 KLHL35 TCF4

1.06e-041892238e6b6025f5554672e26a5d19fe365acb4333789c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

1.06e-04189223dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

MECOM TCF4 RAPGEF4

1.06e-0418922375c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

MECOM TCF4 RAPGEF4

1.06e-04189223c81787a8c662db5d7814c583dd64562857629e81
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

1.06e-04189223f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLHL35 MECOM TCF4

1.06e-04189223360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL35 MECOM TCF4

1.06e-04189223feedac2751ed770f80bc56fec31662b5b3826f58
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM TCF4 RAPGEF4

1.06e-041892237346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM TCF4 RAPGEF4

1.06e-04189223fe49852ba15f948b384d6b4c258927c70b741357
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRK MECOM PTPN13

1.08e-041902238aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

PTPRK MECOM PTPN13

1.08e-04190223ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

PTPRK TCF4 RAPGEF4

1.08e-04190223812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

PTPRK TCF4 RAPGEF4

1.08e-041902237f3f419fffe02934b6f27b697f7a6401072491ed
DiseaseHodgkins lymphoma

PTPRK ERAP1 CDCP2

2.65e-0582213EFO_0000183
Diseaseosteosarcoma, overall survival

MECOM AGMO

3.17e-0512212EFO_0000637, EFO_0000638
Diseasemood instability measurement

ERAP1 SORCS3 TCF4

1.00e-04128213EFO_0008475
Diseasereading and spelling ability

MECOM ZNF57 PTPN13

2.16e-04166213EFO_0005301
Diseasetrauma exposure measurement

SORCS3 AGMO RAPGEF4

2.40e-04172213EFO_0010703
Diseasecardiovascular disease

ERAP1 MECOM SORCS3 DCLRE1B

2.76e-04457214EFO_0000319
DiseaseCalcium channel blocker use measurement

ERAP1 MECOM SORCS3

4.48e-04213213EFO_0009930
Diseaseheart rate

DOCK10 AGMO RAPGEF4

5.26e-04225213EFO_0004326
Diseasesitting height ratio

MECOM TCF4

6.02e-0451212EFO_0007118
Diseaseattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder

SORCS3 TCF4

6.02e-0451212EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
DiseaseBehcet's syndrome

ERAP1 IL22RA2

6.50e-0453212EFO_0003780
DiseasePROSTATE CANCER, HEREDITARY, 1

MECOM TCF4

8.33e-0460212C4722327
DiseaseAntihypertensive use measurement

MECOM SORCS3 TCF4

8.45e-04265213EFO_0009927
DiseaseMicrocephaly

TCF4 AGMO

1.04e-0367212C0025958
DiseaseProstate cancer, familial

MECOM TCF4

1.10e-0369212C2931456
DiseaseAgents acting on the renin-angiotensin system use measurement

ERAP1 MECOM SORCS3

1.66e-03335213EFO_0009931
Diseaseschizophrenia, intelligence, self reported educational attainment

SORCS3 TCF4 RAPGEF4

1.82e-03346213EFO_0004337, EFO_0004784, MONDO_0005090
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

DOCK10 PTPRK SORCS3 TCF4

2.23e-03801214EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseVisual seizure

MPDZ TCF4

2.33e-03101212C0270824
DiseaseEpileptic drop attack

MPDZ TCF4

2.33e-03101212C0270846
DiseaseGeneralized seizures

MPDZ TCF4

2.33e-03101212C0234533
DiseaseClonic Seizures

MPDZ TCF4

2.33e-03101212C0234535
DiseaseVertiginous seizure

MPDZ TCF4

2.33e-03101212C0422855
DiseaseGustatory seizure

MPDZ TCF4

2.33e-03101212C0422854
DiseaseSeizures, Somatosensory

MPDZ TCF4

2.33e-03101212C0422850
DiseaseOlfactory seizure

MPDZ TCF4

2.33e-03101212C0422853
DiseaseSeizures, Auditory

MPDZ TCF4

2.33e-03101212C0422852
DiseaseGeneralized Absence Seizures

MPDZ TCF4

2.33e-03101212C4505436
DiseaseConvulsive Seizures

MPDZ TCF4

2.33e-03101212C0751494
DiseaseSeizures, Sensory

MPDZ TCF4

2.33e-03101212C0751496
DiseaseAtonic Absence Seizures

MPDZ TCF4

2.33e-03101212C0751123
DiseaseComplex partial seizures

MPDZ TCF4

2.33e-03101212C0149958
DiseaseSingle Seizure

MPDZ TCF4

2.33e-03101212C0751110
DiseaseEpileptic Seizures

MPDZ TCF4

2.33e-03101212C4317109
DiseaseJacksonian Seizure

MPDZ TCF4

2.33e-03101212C0022333
DiseaseNon-epileptic convulsion

MPDZ TCF4

2.33e-03101212C0751056
DiseaseNonepileptic Seizures

MPDZ TCF4

2.33e-03101212C3495874
DiseaseTonic Seizures

MPDZ TCF4

2.38e-03102212C0270844
DiseaseAbsence Seizures

MPDZ TCF4

2.38e-03102212C4316903
DiseaseConvulsions

MPDZ TCF4

2.38e-03102212C4048158
DiseaseSeizures, Focal

MPDZ TCF4

2.47e-03104212C0751495
DiseaseMyoclonic Seizures

MPDZ TCF4

2.47e-03104212C4317123
DiseaseTonic - clonic seizures

MPDZ TCF4

2.47e-03104212C0494475
Diseaseage at first birth measurement

SORCS3 TCF4

3.27e-03120212EFO_0009101
Diseasedepressive symptom measurement

SORCS3 OBI1 TCF4

3.28e-03426213EFO_0007006
DiseaseTinnitus

SORCS3 PTPN13

3.83e-03130212HP_0000360
Diseasecorneal resistance factor

MROH9 TCF4 PTPN13

3.84e-03451213EFO_0010067
Diseaseirritable bowel syndrome

SORCS3 TCF4

3.89e-03131212EFO_0000555
Diseaseunipolar depression, mood disorder

SORCS3 TCF4

4.06e-03134212EFO_0003761, EFO_0004247
Diseaseemphysema imaging measurement

PTPRK MROH9

4.80e-03146212EFO_0007626
Diseaseparental longevity

DCLRE1B RAPGEF4 SORCS1

4.96e-03494213EFO_0007796
Diseasediabetic nephropathy

SORCS3 AGMO

5.06e-03150212EFO_0000401
Diseasemean arterial pressure

DOCK10 ERAP1 MECOM

5.10e-03499213EFO_0006340
Diseaseintraocular pressure measurement

MROH9 MECOM TCF4

5.39e-03509213EFO_0004695
Diseasemajor depressive disorder

SORCS3 TCF4

5.39e-03155212MONDO_0002009
Diseaseunipolar depression, bipolar disorder

SORCS3 TCF4

5.46e-03156212EFO_0003761, MONDO_0004985

Protein segments in the cluster

PeptideGeneStartEntry
HEVNIMWAGHQTHHS

AGMO

136

Q6ZNB7
SSWHVMSVIFHSDKH

CDCP2

116

Q5VXM1
HMHSDHTVGLSSTWA

DCLRE1B

31

Q9H816
HSTSHSSSNVWHSMA

MECOM

1201

Q03112
HHSSDPWSSSSGMNQ

TCF4

221

P15884
SSSHWHQEGVDVKTM

ERAP1

506

Q9NZ08
SSEMHSLHNHLQSPW

OBI1

676

Q5W0B1
SMKSSHQKPSGCWQH

IL22RA2

71

Q969J5
QDSVKWHHMAHKVNS

MROH9

16

Q5TGP6
SQWMHSTSSHEGHKQ

DOCK10

1421

Q96BY6
HMQHSKWQHPSDLTT

S100PBP

356

Q96BU1
MQDSAIDSSSKDHHW

PTPN13

1206

Q12923
TVSNLWNSTHHVFMH

PTPRK

546

Q15262
MVAAHAAHSSSSAEW

RAPGEF4

1

Q8WZA2
SSTKHWASMHVSDHS

PTAR1

221

Q7Z6K3
QTSMDHSHHWVFLGN

TMEM132E

926

Q6IEE7
TGDSAHNQAMVHWSG

SORCS3

191

Q9UPU3
HNQAMVHWSGHNSSV

SORCS3

196

Q9UPU3
STISAHSNPVHWQHM

MPDZ

241

O75970
WSSSLANHKSMHTGE

ZNF679

391

Q8IYX0
TWSSTLHNHVRMHTG

ZNF57

486

Q68EA5
SAHNQAMVHWSGHNS

SORCS1

171

Q8WY21
GGHINSHDVWMFSSH

KLHL35

356

Q6PF15