Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPM6 TSPOAP1 ABCC11 TMC4 AQP3 TMC3 ABCA10 SLC1A5 ABCC6 CHRNA5 SLC2A5 ITPR3 NALF1 SLC30A5 SLC18A3 ABCC12 TMC5 FXYD1 ATP2A1 ATP2A2 SVOP SLC38A3 SLC2A11 MCOLN3	7.76e-09	1180	105	24	GO:0022857
GeneOntologyMolecularFunction	transporter activity	TRPM6 TSPOAP1 ABCC11 TMC4 AQP3 TMC3 ABCA10 SLC1A5 ABCC6 CHRNA5 SLC2A5 ITPR3 NALF1 SLC30A5 SLC18A3 ABCC12 TMC5 FXYD1 ATP2A1 ATP2A2 SVOP SLC38A3 SLC2A11 MCOLN3	4.22e-08	1289	105	24	GO:0005215
GeneOntologyMolecularFunction	mechanosensitive monoatomic ion channel activity	TMC4 TMC3 NALF1 TMC5	2.09e-06	18	105	4	GO:0008381
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPM6 TSPOAP1 ITPR3 NALF1 ATP2A1 ATP2A2 MCOLN3	1.51e-05	151	105	7	GO:0015085
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPM6 TSPOAP1 TMC4 TMC3 CHRNA5 ITPR3 NALF1 SLC30A5 SLC18A3 TMC5 FXYD1 ATP2A1 ATP2A2 SLC38A3 MCOLN3	1.68e-05	793	105	15	GO:0015075
GeneOntologyMolecularFunction	channel activity	TRPM6 TSPOAP1 TMC4 AQP3 TMC3 SLC1A5 CHRNA5 ITPR3 NALF1 TMC5 FXYD1 MCOLN3	2.04e-05	525	105	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPM6 TSPOAP1 TMC4 AQP3 TMC3 SLC1A5 CHRNA5 ITPR3 NALF1 TMC5 FXYD1 MCOLN3	2.08e-05	526	105	12	GO:0022803
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC11 ABCA10 ABCC6 ABCC12 ATP2A1 ATP2A2	2.39e-05	109	105	6	GO:0042626
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPM6 TSPOAP1 ABCC11 AQP3 ABCC6 ITPR3 NALF1 SLC30A5 SLC18A3 FXYD1 ATP2A1 ATP2A2 SLC38A3 MCOLN3	4.28e-05	758	105	14	GO:0015318
GeneOntologyMolecularFunction	gated channel activity	TSPOAP1 TMC4 TMC3 SLC1A5 CHRNA5 ITPR3 NALF1 TMC5 MCOLN3	6.76e-05	334	105	9	GO:0022836
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC11 ABCA10 ABCC6 ABCC12	1.27e-04	49	105	4	GO:0140359
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM6 TSPOAP1 TMC4 TMC3 CHRNA5 ITPR3 NALF1 TMC5 FXYD1 MCOLN3	1.54e-04	459	105	10	GO:0005216
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC11 ABCA10 SLC1A5 ABCC6 SLC30A5 SLC18A3 ABCC12 ATP2A1 ATP2A2 SLC38A3	2.09e-04	477	105	10	GO:0022804
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	GPR32 GPR32P1	2.71e-04	5	105	2	GO:0004982
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC11 ABCA10 ABCC6 ABCC12 ATP2A1 ATP2A2	3.58e-04	178	105	6	GO:0015399
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC11 TOR4A ABCA10 ABCC6 SHOC1 ABCC12 ATP2A1 ATP2A2 DNAH9	5.33e-04	441	105	9	GO:0016887
GeneOntologyMolecularFunction	calcium channel activity	TRPM6 TSPOAP1 ITPR3 NALF1 MCOLN3	6.00e-04	129	105	5	GO:0005262
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPM6 TSPOAP1 CHRNA5 ITPR3 NALF1 SLC30A5 SLC18A3 ATP2A1 ATP2A2 SLC38A3 MCOLN3	7.42e-04	664	105	11	GO:0008324
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC11 ABCC6	7.51e-04	8	105	2	GO:0015431
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPM6 TSPOAP1 ITPR3 NALF1 SLC30A5 ATP2A1 ATP2A2 SLC38A3 MCOLN3	7.77e-04	465	105	9	GO:0046873
GeneOntologyMolecularFunction	fructose transmembrane transporter activity	SLC2A5 SLC2A11	9.63e-04	9	105	2	GO:0005353
GeneOntologyMolecularFunction	L-glutamine transmembrane transporter activity	SLC1A5 SLC38A3	9.63e-04	9	105	2	GO:0015186
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC11 ABCC6	1.20e-03	10	105	2	GO:0043225
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	AQP3 SLC2A5 SLC2A11	1.40e-03	42	105	3	GO:0015144
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2A1 ATP2A2	1.46e-03	11	105	2	GO:0005388
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPM6 TSPOAP1 ITPR3 NALF1 SLC30A5 SLC18A3 ATP2A1 ATP2A2 SLC38A3 MCOLN3	1.72e-03	627	105	10	GO:0022890
GeneOntologyMolecularFunction	complement receptor activity	GPR32 GPR32P1	2.39e-03	14	105	2	GO:0004875
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC11 ABCC6	2.75e-03	15	105	2	GO:0008559
GeneOntologyBiologicalProcess	positive regulation of endoplasmic reticulum calcium ion concentration	TMTC4 ATP2A1 ATP2A2	1.28e-07	3	105	3	GO:0032470
GeneOntologyBiologicalProcess	monoatomic ion transport	TRPM6 TSPOAP1 ABCC11 TMC4 TMC3 ABCC6 CHRNA5 ITPR3 NALF1 SLC30A5 TMEM168 SLC18A3 UCN KEL TMC5 FXYD1 ATP2A1 ATP2A2 SLC38A3 CRBN MCOLN3 CNR1	1.29e-06	1374	105	22	GO:0006811
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	TRPM6 TSPOAP1 ABCC11 TMC4 TMC3 ABCC6 CHRNA5 ITPR3 NALF1 SLC30A5 TMEM168 SLC18A3 KEL TMC5 FXYD1 ATP2A1 ATP2A2 CRBN MCOLN3	3.15e-06	1115	105	19	GO:0034220
GeneOntologyBiologicalProcess	glutamine secretion	SLC1A5 SLC38A3	2.57e-05	2	105	2	GO:0010585
GeneOntologyBiologicalProcess	calcium ion homeostasis	TSPOAP1 ABCC6 ITPR3 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	2.98e-05	389	105	10	GO:0055074
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell contraction	DSC2 FXYD1 ATP2A1 ATP2A2	6.72e-05	43	105	4	GO:0086004
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	TSPOAP1 ITPR3 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	9.18e-05	359	105	9	GO:0006874
GeneOntologyBiologicalProcess	regulation of cardiac muscle contraction	DSC2 UCN FXYD1 ATP2A1 ATP2A2	9.18e-05	89	105	5	GO:0055117
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	PDE3B TSPOAP1 LRRK2 ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 SLC38A3 CNR1	1.26e-04	866	105	14	GO:0055082
GeneOntologyBiologicalProcess	cellular homeostasis	PDE3B TSPOAP1 LRRK2 ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 UBE2S KEL FXYD1 ATP2A1 ATP2A2 SLC38A3 CNR1	1.31e-04	981	105	15	GO:0019725
GeneOntologyBiologicalProcess	regulation of actin filament-based movement	DSC2 FXYD1 ATP2A1 ATP2A2	1.53e-04	53	105	4	GO:1903115
GeneOntologyBiologicalProcess	chemical homeostasis	PDE3B TSPOAP1 LRRK2 AQP3 LYST ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 CYP7B1 KEL FXYD1 ATP2A1 ATP2A2 SLC38A3 CNR1	1.83e-04	1249	105	17	GO:0048878
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	TSPOAP1 LRRK2 ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	2.47e-04	705	105	12	GO:0055080
GeneOntologyBiologicalProcess	L-glutamine import across plasma membrane	SLC1A5 SLC38A3	2.54e-04	5	105	2	GO:1903803
GeneOntologyBiologicalProcess	regulation of striated muscle contraction	DSC2 UCN FXYD1 ATP2A1 ATP2A2	2.60e-04	111	105	5	GO:0006942
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	TSPOAP1 LRRK2 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	2.83e-04	611	105	11	GO:0030003
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	TSPOAP1 LRRK2 ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	2.88e-04	717	105	12	GO:0050801
GeneOntologyBiologicalProcess	inorganic ion homeostasis	TSPOAP1 ABCC6 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	3.29e-04	622	105	11	GO:0098771
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	TSPOAP1 LRRK2 ITPR3 SLC30A5 TMTC4 PDZD8 KEL FXYD1 ATP2A1 ATP2A2 CNR1	3.29e-04	622	105	11	GO:0006873
GeneOntologyBiologicalProcess	endoplasmic reticulum calcium ion homeostasis	TMTC4 ATP2A1 ATP2A2	4.25e-04	29	105	3	GO:0032469
GeneOntologyCellularComponent	platelet dense tubular network membrane	ITPR3 ATP2A1 ATP2A2	1.10e-05	9	108	3	GO:0031095
GeneOntologyCellularComponent	platelet dense tubular network	ITPR3 ATP2A1 ATP2A2	2.15e-05	11	108	3	GO:0031094
Domain	TMC	TMC4 TMC3 TMC5	8.94e-06	8	103	3	PF07810
Domain	TMC	TMC4 TMC3 TMC5	8.94e-06	8	103	3	IPR012496
Domain	TMEM191C	TMEM191C TMEM191B	3.01e-05	2	103	2	PF15194
Domain	TMEM191B/C	TMEM191C TMEM191B	3.01e-05	2	103	2	IPR028186
Domain	ABC_transporter_CS	ABCC11 ABCA10 ABCC6 ABCC12	8.31e-05	42	103	4	IPR017871
Domain	P-type_ATPase_IIA	ATP2A1 ATP2A2	9.00e-05	3	103	2	IPR005782
Domain	ABC_tran	ABCC11 ABCA10 ABCC6 ABCC12	1.41e-04	48	103	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCC11 ABCA10 ABCC6 ABCC12	1.41e-04	48	103	4	PS50893
Domain	AAA+_ATPase	ABCC11 TOR4A ABCA10 ABCC6 ABCC12 DNAH9	1.46e-04	144	103	6	IPR003593
Domain	AAA	ABCC11 TOR4A ABCA10 ABCC6 ABCC12 DNAH9	1.46e-04	144	103	6	SM00382
Domain	ABC_TRANSPORTER_1	ABCC11 ABCA10 ABCC6 ABCC12	1.53e-04	49	103	4	PS00211
Domain	ABC_transporter-like	ABCC11 ABCA10 ABCC6 ABCC12	1.65e-04	50	103	4	IPR003439
Domain	ABC_membrane	ABCC11 ABCC6 ABCC12	3.03e-04	24	103	3	PF00664
Domain	ABC_TM1F	ABCC11 ABCC6 ABCC12	4.83e-04	28	103	3	PS50929
Domain	ABC1_TM_dom	ABCC11 ABCC6 ABCC12	4.83e-04	28	103	3	IPR011527
Domain	ARM-like	LRRK2 HEATR1 MEI1 HEATR6 NALF1 AP2A1 HEATR9	7.43e-04	270	103	7	IPR011989
Domain	MFS_sugar_transport-like	SLC2A5 SVOP SLC2A11	1.02e-03	36	103	3	IPR005828
Domain	Sugar_tr	SLC2A5 SVOP SLC2A11	1.02e-03	36	103	3	PF00083
Domain	Hydrolase_3	ATP2A1 ATP2A2	1.32e-03	10	103	2	PF08282
Domain	Sugar/inositol_transpt	SLC2A5 SLC2A11	2.62e-03	14	103	2	IPR003663
Domain	ARM-type_fold	LRRK2 HEATR1 MEI1 LYST HEATR6 AP2A1 HEATR9	2.73e-03	339	103	7	IPR016024
Domain	MFS	SLC2A5 SLC18A3 SVOP SLC2A11	3.01e-03	108	103	4	PS50850
Domain	-	ATP2A1 ATP2A2	3.44e-03	16	103	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2A1 ATP2A2	3.44e-03	16	103	2	IPR023298
Domain	SUGAR_TRANSPORT_2	SLC2A5 SLC2A11	3.88e-03	17	103	2	PS00217
Domain	ATPase_P-typ_cation-transptr_C	ATP2A1 ATP2A2	3.88e-03	17	103	2	IPR006068
Domain	Cation_ATPase_C	ATP2A1 ATP2A2	3.88e-03	17	103	2	PF00689
Domain	Cadherin	DSC2 PCDHGA11 PCDHGA4 FREM3	4.14e-03	118	103	4	IPR002126
Domain	Cation_ATPase_N	ATP2A1 ATP2A2	4.35e-03	18	103	2	PF00690
Domain	Cation_ATPase_N	ATP2A1 ATP2A2	4.35e-03	18	103	2	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2A1 ATP2A2	4.84e-03	19	103	2	IPR004014
Domain	DEP	GPR155 PREX1	6.47e-03	22	103	2	PF00610
Domain	DEP	GPR155 PREX1	6.47e-03	22	103	2	PS50186
Domain	DEP	GPR155 PREX1	6.47e-03	22	103	2	SM00049
Domain	MFS_dom	SLC2A5 SLC18A3 SVOP SLC2A11	6.48e-03	134	103	4	IPR020846
Domain	DEP_dom	GPR155 PREX1	7.07e-03	23	103	2	IPR000591
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	TRPM6 ABCC11 AQP3 ABCA10 SLC1A5 ABCC6 SLC30A5 AP2A1 FXYD1 ATP2A1 ATP2A2 SLC38A3 SLC2A11 MCOLN3	2.43e-05	736	74	14	M27287
Pathway	KEGG_ABC_TRANSPORTERS	ABCC11 ABCA10 ABCC6 ABCC12	8.10e-05	44	74	4	M11911
Pathway	REACTOME_ION_HOMEOSTASIS	ITPR3 FXYD1 ATP2A1 ATP2A2	1.81e-04	54	74	4	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	ITPR3 FXYD1 ATP2A1 ATP2A2	1.81e-04	54	74	4	MM15202
Pubmed	Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.	TMC4 TMC3 TMC5	1.70e-06	8	110	3	12906855
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	ITPR3 ATP2A1 ATP2A2	1.70e-06	8	110	3	19033399
Pubmed	TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.	TMC4 TMC3 TMC5	1.70e-06	8	110	3	12812529
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCC11 ABCA10 ABCC12	3.63e-06	10	110	3	11435397
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDE3B POLR1A DSC2 EARS2 HEATR1 URB2 SLC1A5 NUP205 ITPR3 NAA25 AP2A1 COG5 ATP2A2	9.15e-06	942	110	13	31073040
Pubmed	Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.	ATP2A1 ATP2A2	9.91e-06	2	110	2	12556521
Pubmed	Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.	ATP2A1 ATP2A2	9.91e-06	2	110	2	19644701
Pubmed	Cannabinoid modulation of midbrain urocortin 1 neurones during acute and chronic stress.	UCN CNR1	9.91e-06	2	110	2	22734681
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.	ATP2A1 ATP2A2	9.91e-06	2	110	2	14638697
Pubmed	Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.	ABCC11 ABCC12	9.91e-06	2	110	2	11688999
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.	ATP2A1 ATP2A2	9.91e-06	2	110	2	10603953
Pubmed	Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.	ATP2A1 ATP2A2	9.91e-06	2	110	2	34769190
Pubmed	Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.	ATP2A1 ATP2A2	9.91e-06	2	110	2	18953100
Pubmed	Muscle RANK is a key regulator of Ca2+ storage, SERCA activity, and function of fast-twitch skeletal muscles.	TNFRSF11A ATP2A2	9.91e-06	2	110	2	26825123
Pubmed	SERCA overexpression reduces hydroxyl radical injury in murine myocardium.	ATP2A1 ATP2A2	9.91e-06	2	110	2	16798816
Pubmed	Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.	ABCC11 ABCC12	9.91e-06	2	110	2	11483364
Pubmed	GPR155: Gene organization, multiple mRNA splice variants and expression in mouse central nervous system.	GPR155 CNR1	9.91e-06	2	110	2	20537985
Pubmed	Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.	ATP2A1 ATP2A2	9.91e-06	2	110	2	12975374
Pubmed	Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.	ATP2A1 ATP2A2	9.91e-06	2	110	2	15718407
Pubmed	SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.	ATP2A1 ATP2A2	9.91e-06	2	110	2	11402072
Pubmed	An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction.	ITPR3 CNR1	2.97e-05	3	110	2	26037800
Pubmed	Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.	BUB1 LTA	2.97e-05	3	110	2	18922873
Pubmed	Cloning genes encoding receptors related to chemoattractant receptors.	GPR32 GPR32P1	2.97e-05	3	110	2	9653656
Pubmed	Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.	ATP2A1 ATP2A2	2.97e-05	3	110	2	27055500
Pubmed	Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway.	SLC1A5 SLC38A3	2.97e-05	3	110	2	21812036
Pubmed	Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart.	ATP2A1 ATP2A2	2.97e-05	3	110	2	25615793
Pubmed	Phospholamban domain IB forms an interaction site with the loop between transmembrane helices M6 and M7 of sarco(endo)plasmic reticulum Ca2+ ATPases.	ATP2A1 ATP2A2	2.97e-05	3	110	2	11526231
Pubmed	The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.	ATP2A1 ATP2A2	2.97e-05	3	110	2	16410239
Pubmed	Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.	ATP2A1 ATP2A2	2.97e-05	3	110	2	15972723
Pubmed	RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.	TNFRSF11A LTA	2.97e-05	3	110	2	17502664
Pubmed	Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.	ATP2A1 ATP2A2	2.97e-05	3	110	2	16754798
Pubmed	The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls.	CRBN CNR1	2.97e-05	3	110	2	38514794
Pubmed	Coordinate regulation of SR Ca(2+)-ATPase and phospholamban expression in developing murine heart.	ATP2A1 ATP2A2	2.97e-05	3	110	2	9038922
Pubmed	Specific effects of endurance and sprint training on protein expression of calsequestrin and SERCA in mouse skeletal muscle.	ATP2A1 ATP2A2	2.97e-05	3	110	2	22466636
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	POLR1A HEATR1 SLC1A5 NUP205 ATP2A1 ATP2A2	4.62e-05	202	110	6	24639526
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 CD22	5.92e-05	4	110	2	12646615
Pubmed	Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs).	ATP2A1 ATP2A2	5.92e-05	4	110	2	12032137
Pubmed	Myeloid related proteins are up-regulated in autoimmune thyroid diseases and activate toll-like receptor 4 and pro-inflammatory cytokines in vitro.	ABCC11 ABCC6	5.92e-05	4	110	2	29656212
Pubmed	Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.	TAS2R3 TAS2R50	5.92e-05	4	110	2	32227702
Pubmed	The nongastric H+-K+-ATPases: molecular and functional properties.	ATP2A1 ATP2A2	5.92e-05	4	110	2	10362770
Pubmed	Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle.	ATP2A1 ATP2A2	5.92e-05	4	110	2	12074580
Pubmed	Insulin receptor substrate proteins create a link between the tyrosine phosphorylation cascade and the Ca2+-ATPases in muscle and heart.	ATP2A1 ATP2A2	5.92e-05	4	110	2	9295312
Pubmed	TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis.	ITPR3 ATP2A2	5.92e-05	4	110	2	25996873
Pubmed	CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain.	CD38 ATP2A1	5.92e-05	4	110	2	12403647
Pubmed	Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.	ATP2A1 ATP2A2	5.92e-05	4	110	2	25110346
Pubmed	SERCA1a can functionally substitute for SERCA2a in the heart.	ATP2A1 ATP2A2	5.92e-05	4	110	2	9887021
Pubmed	Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.	ATP2A1 ATP2A2	5.92e-05	4	110	2	10555147
Pubmed	The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.	ATP2A1 ATP2A2	9.85e-05	5	110	2	30299255
Pubmed	ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.	ITPR3 ATP2A2	1.47e-04	6	110	2	16352659
Pubmed	Screening of LRRK2 interactants by yeast 2-hybrid analysis.	STRBP LRRK2	1.47e-04	6	110	2	19001729
Pubmed	Functional significance of isoform diversification in the protocadherin gamma gene cluster.	PCDHGA11 PCDHGA4 SLC18A3	1.72e-04	34	110	3	22884324
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	NRCAM TMC4 BIRC6 MEX3A UBE2S	2.01e-04	168	110	5	30631154
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	ATP2A1 ATP2A2	2.06e-04	7	110	2	24786561
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	POLR1A STRBP HEATR1 URB2 BIRC6 NUP205 ITPR3 ATP2A2 NUP160	2.37e-04	653	110	9	22586326
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	ITPR3 ATP2A1 ATP2A2	2.40e-04	38	110	3	30786075
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2A1 ATP2A2	2.74e-04	8	110	2	10951186
Pubmed	Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.	TNFRSF11A LTA	2.74e-04	8	110	2	21441458
Pubmed	Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.	ATP2A1 ATP2A2	2.74e-04	8	110	2	27967605
Pubmed	Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.	SLC18A3 CNR1	2.74e-04	8	110	2	23319656
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC6 ABCC12	2.74e-04	8	110	2	15802388
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	ATP2A1 ATP2A2	2.74e-04	8	110	2	11784029
Pubmed	Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.	ATP2A1 ATP2A2	2.74e-04	8	110	2	27923914
Pubmed	Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss.	TMTC4 ATP2A2	2.74e-04	8	110	2	30188326
Pubmed	Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse.	ABCC11 ABCC12	3.52e-04	9	110	2	26122848
Pubmed	The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.	ATP2A1 ATP2A2	3.52e-04	9	110	2	15253893
Pubmed	A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.	ATP2A1 ATP2A2	3.52e-04	9	110	2	25640239
Pubmed	Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.	TNFRSF11A NUP205	3.52e-04	9	110	2	21623375
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	POLR1A STRBP HEATR1 URB2 SLC1A5 NUP205 ITPR3 AP2A1 SVIL ATP2A2 NUP160	4.10e-04	1024	110	11	24711643
Pubmed	The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.	BUB1 UBE2S	5.35e-04	11	110	2	26912231
Pubmed	The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis.	ATP2A1 ATP2A2	5.35e-04	11	110	2	12122109
Pubmed	Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development.	NRCAM SLC18A3	5.35e-04	11	110	2	29536590
Pubmed	Identification of new high affinity targets for Roquin based on structural conservation.	STRBP MEX3A	5.35e-04	11	110	2	30295819
Pubmed	SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I.	POLR1A SHOC1	7.56e-04	13	110	2	30746471
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TPST2 TOR4A BIRC6 LYST SLC1A5 ITPR3 AP2A1 TP53I13 PDZD8 LRRC14 PREX1	7.69e-04	1105	110	11	35748872
Pubmed	Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.	HEATR1 LYST	8.80e-04	14	110	2	11472062
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	PDE3B DSC2 SQLE BIRC6 SLC1A5 NUP205 SLC30A5 PDZD8 ATP2A2 SLC38A3	8.97e-04	952	110	10	38569033
Pubmed	LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.	LRRK2 AP2A1	1.01e-03	15	110	2	21307259
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGA11 PCDHGA4	1.01e-03	15	110	2	23515096
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	LRRK2 SLC1A5 ATP2A2	1.02e-03	62	110	3	26508657
Pubmed	Location of mouse and human genes corresponding to conserved canine olfactory receptor gene subfamilies.	OR2F2 OR2F1	1.31e-03	17	110	2	9545490
Pubmed	Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.	ATP2A1 ATP2A2	1.31e-03	17	110	2	22411552
Pubmed	Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo.	ATP2A1 ATP2A2	1.47e-03	18	110	2	22522309
Pubmed	Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.	PDE3B NALF1	1.64e-03	19	110	2	25208829
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	POLR1A STRBP NEK3 AP2A1 SVIL UBE2S	1.75e-03	400	110	6	35013556
Pubmed	Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.	ATP2A1 ATP2A2	1.81e-03	20	110	2	18978355
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	POLR1A STRBP HEATR1 URB2 BIRC6 NUP205 AP2A1 NUP160	1.82e-03	704	110	8	29955894
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	DSC2 TSPOAP1 PCDHGA11 IL18BP HEATR1 LYST TRANK1	1.90e-03	552	110	7	10737800
Pubmed	Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis.	POLR1A SHOC1	2.00e-03	21	110	2	30272023
Pubmed	A novel family of mammalian taste receptors.	TAS2R3 TAS2R50	2.00e-03	21	110	2	10761934
Pubmed	Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.	ATP2A1 ATP2A2	2.20e-03	22	110	2	35081489
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA10 ABCC6	2.20e-03	22	110	2	8894702
Pubmed	Identification of Modifier Genes in a Mouse Model of Gaucher Disease.	ITPR3 PDZD8	2.20e-03	22	110	2	27568557
Pubmed	Human ORFeome version 1.1: a platform for reverse proteomics.	NEK3 TMTC4	2.20e-03	22	110	2	15489335
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R3 TAS2R50	2.20e-03	22	110	2	12734386
Pubmed	The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.	ATP2A1 ATP2A2	2.20e-03	22	110	2	28890335
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R3 TAS2R50	2.40e-03	23	110	2	20022913
Pubmed	Discovery and fine mapping of serum protein loci through transethnic meta-analysis.	TNFRSF11A CHRNA5	2.40e-03	23	110	2	23022100
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	TPST2 LAYN NR4A3 TNFRSF11A AQP3 TAS2R3 UCN ATP2A1 MCOLN3	2.53e-03	915	110	9	32393512
Pubmed	ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.	PDE3B ITPR3 AP2A1 PDZD8 ATP2A2	2.67e-03	299	110	5	37931956
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	GPR155 TPST2 STRBP SQLE AP2A1 TMTC4 PREX1 SLC38A3	2.68e-03	750	110	8	11230166
Cytoband	7q35	OR2F2 OR2A5 OR2F1	3.21e-04	55	110	3	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	OR2F2 OR2A5 OR2F1	5.49e-04	66	110	3	chr7q35
GeneFamily	Transmembrane channel likes	TMC4 TMC3 TMC5	3.63e-06	8	74	3	1135
GeneFamily	ATP binding cassette subfamily C	ABCC11 ABCC6 ABCC12	1.83e-05	13	74	3	807
GeneFamily	ATPases Ca2+ transporting	ATP2A1 ATP2A2	5.84e-04	9	74	2	1209
CoexpressionAtlas	B cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3	GPR155 STRBP LRRK2 ITPR3 FRY HEATR6 CD22 CD38 NUP160	3.95e-05	348	100	9	GSM538216_500
CoexpressionAtlas	B cells, B.T1.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23-, Spleen, avg-3	GPR155 STRBP LRRK2 ITPR3 FRY HEATR6 CD22 CD38 NUP160	4.41e-05	353	100	9	GSM538213_500
CoexpressionAtlas	B cells, B.FrE.FL, AA4.1+ IgM+ CD19+ CD43- CD24+, Fetal Liver, avg-3	GPR155 STRBP LRRK2 ITPR3 FRY HEATR6 CD22 CD38 BUB1	6.60e-05	372	100	9	GSM538204_500
CoexpressionAtlas	B cells, B.FrE.BM, CD19+ IgM+ AA4.1+ HSA+, Bone marrow, avg-3	GPR155 STRBP LRRK2 SLC1A5 ITPR3 FRY HEATR6 CD22 CD38	7.17e-05	376	100	9	GSM399438_500
ToppCell	Mild-CD4+_T\|World / Disease group and Cell class	TMEM191C AQP3 CLDN9 TRANK1 ATRIP LTA IL26	3.45e-07	183	109	7	c4ac8893d38a3da4e19fe2ef1756bd69c89e975c
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRCAM STRBP MEI1 CFAP54 CD22 CD38 IL26	5.67e-07	197	109	7	0f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TMPRSS12 WFDC1 CFAP54 NALF1 HEATR9 SVOP	1.07e-06	136	109	6	27a41463e6f16deb5b1d4f17fefded9959038c07
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMPRSS12 WFDC1 CFAP54 NALF1 HEATR9 SVOP	1.07e-06	136	109	6	88b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK3 FRY MEX3A KEL LTA MCOLN3	2.13e-06	153	109	6	a8f83ec640fae51d4fba34b92e3d6cca4999e930
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK3 FRY MEX3A KEL LTA MCOLN3	3.07e-06	163	109	6	66ecd544d7b52e61880b125bf39d1f406af6900a
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLR1A NUP205 ATRIP CD22 LTA CRBN	3.91e-06	170	109	6	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	MEI1 TMC3 SLC2A5 CFAP54 CD38 IL26	4.62e-06	175	109	6	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	HEATR1 LYST SLC1A5 TMEM168 CD38 LTA	4.77e-06	176	109	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	Mild-CD4+_T\|Mild / Disease group and Cell class	LRRK2 AQP3 FRY SVIL LTA IL26	6.35e-06	185	109	6	c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRRK2 TMC4 AQP3 ABCC6 TMC5 CNR1	7.40e-06	190	109	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PDE3B NRCAM FRY NALF1 KEL	7.40e-06	190	109	6	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRCAM STRBP MEI1 CFAP54 CD38 IL26	8.83e-06	196	109	6	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRCAM ARHGDIG NALF1 SLC18A3 SVOP CNR1	9.09e-06	197	109	6	f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell	mild-Plasmablast\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MEI1 AQP3 SLC1A5 SLC2A5 CD38 BUB1	9.36e-06	198	109	6	b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TPST2 MEI1 CFAP54 CD38 CNR1 IL26	9.63e-06	199	109	6	2f60682f1b82918a65e8851e99c9e3398845b62f
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TPST2 MEI1 CFAP54 CD38 CNR1 IL26	9.63e-06	199	109	6	58242d78517c05fa367a7c6edac57ef79107453c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SQLE LRRK2 AQP3 ITPR3 EVA1A TMC5	9.63e-06	199	109	6	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SQLE LRRK2 AQP3 ITPR3 EVA1A TMC5	9.63e-06	199	109	6	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	LAYN AQP3 LYST ITPR3 TRANK1 CD38	9.63e-06	199	109	6	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TPST2 MEI1 CFAP54 CD38 CNR1 IL26	9.91e-06	200	109	6	e1b3fc516887510b18cf688ada0e00b5f5eff684
ToppCell	Parenchymal-10x3prime_v2-Epithelial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK2 TMC4 AQP3 ABCC6 EVA1A TMC5	9.91e-06	200	109	6	16828c6a2be66bbbd805453325d6da719f2dea1b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC2 AQP3 RTL1 LTA	1.97e-05	65	109	4	d90513969c0147c48403ce0155580a97f44ba716
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x-Inhibitory_Neuron.Gad1Gad2_Sst.Pcdh11x_(Interneuron,_OLM4_(Dentate_enriched?))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC2 AQP3 RTL1 LTA	1.97e-05	65	109	4	f7f4560363bacad033154a402d7593aa5ebfb2e7
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x-Inhibitory_Neuron.Gad1Gad2_Sst.Pcdh11x_(Interneuron,_OLM4_(Dentate_enriched?))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC2 AQP3 RTL1 LTA	1.97e-05	65	109	4	d6ad7b63bc09fdc05a1245bf66d3c5a46e622ba5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 LAYN TMEM191C ABCA10 SVOP	3.51e-05	151	109	5	f41c6558a5874b6464c157027fdf202257c60e5b
ToppCell	COVID-19-kidney-Plasma\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STRBP MEI1 SLC2A5 CFAP54 CD38	4.63e-05	160	109	5	f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCell	ICU-NoSEP-Lymphocyte-B-Plasmablast\|ICU-NoSEP / Disease, Lineage and Cell Type	MEI1 AQP3 SLC2A5 CD38 TMC5	4.77e-05	161	109	5	8ca34d800551cb0f796293e6bfdcbf58509cc668
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LAYN NAA25 HEATR6 CYP7B1 ATP2A1	4.91e-05	162	109	5	64353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LAYN NAA25 HEATR6 CYP7B1 ATP2A1	5.06e-05	163	109	5	9f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM191C ITPR3 CD22 PDZD8 KEL	5.52e-05	166	109	5	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM191C ITPR3 CD22 PDZD8 KEL	5.52e-05	166	109	5	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TPST2 MEI1 CHRNA5 CD38 BUB1	5.68e-05	167	109	5	0130743084dbcb20e10f96715d30961122150cbf
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B NR4A3 HEATR6 UBE2S PREX1	5.68e-05	167	109	5	4b6853efefea5178280ba7c31facda0fbd1cc469
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TPST2 MEI1 CHRNA5 CD38 BUB1	5.68e-05	167	109	5	7bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TPST2 MEI1 CHRNA5 CD38 BUB1	5.68e-05	167	109	5	c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC2 SLC2A5 CD68 TMC5 OCSTAMP	6.71e-05	173	109	5	b75353fcbc9f8cdb21d4f10ddbc93a83fd797a3c
ToppCell	10x3'2.3-week_17-19-Lymphocytic_T-T_NK-Treg\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GPR155 LAYN MEI1 AQP3 LTA	6.89e-05	174	109	5	7ca39c9ecd609e5ade30dac1a948a4a4fff1b3b2
ToppCell	Healthy_donor-Treg\|World / disease group, cell group and cell class (v2)	GPR155 PDE3B LAYN AQP3 CYP7B1	6.89e-05	174	109	5	dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	POLR1A TMEM191C NR4A3 CFAP54 TMEM191B	7.28e-05	176	109	5	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 CHRNA5 ARHGDIG NALF1 SVOP	7.47e-05	177	109	5	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	STRBP ABCC6 CD22 FXYD1 SLC38A3	8.30e-05	181	109	5	0bc58c8942491e7ee5b858c5742770df7677532f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MEI1 TRANK1 CD22 CD38 IL26	8.30e-05	181	109	5	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NRCAM ARHGDIG SLC18A3 SVOP CNR1	8.52e-05	182	109	5	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	STRBP MEI1 CD38 BUB1 IL26	8.75e-05	183	109	5	2c016bb59f131a0e821853b085289a3583f0a729
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|lung / Disease (COVID-19 only), tissue and cell type	STRBP MEI1 SLC2A5 CD38 BUB1	8.97e-05	184	109	5	480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell	wk_08-11-Hematologic_Lymphocytic-T_&_ILC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MEI1 AQP3 LTA PREX1 IL26	8.97e-05	184	109	5	51ae0963b4fb034c3f605ee4e5da513cba7aca35
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 TMPRSS12 ITPR3 EVA1A TMC5	8.97e-05	184	109	5	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 TMPRSS12 ITPR3 EVA1A TMC5	8.97e-05	184	109	5	2a8338e94937686a148b5433515700ca0f674058
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MEI1 TMC3 CFAP54 CD38 IL26	9.20e-05	185	109	5	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGDIG FRY SLC18A3 UCN CNR1	9.20e-05	185	109	5	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	mild-Lymphocytic-Plasmablast\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MEI1 AQP3 SLC2A5 CD38 BUB1	9.44e-05	186	109	5	060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRCAM ARHGDIG NALF1 SLC18A3 SVOP	9.93e-05	188	109	5	bd091503f580dedab40e0996273101285d24b586
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AQP3 ABCC6 EVA1A TMC5	1.02e-04	189	109	5	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B NRCAM FRY NALF1 KEL	1.02e-04	189	109	5	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	severe_COVID-19-Plasmablast\|severe_COVID-19 / disease group, cell group and cell class (v2)	AQP3 CHRNA5 SLC2A5 CD38 BUB1	1.02e-04	189	109	5	953143b2c2e87a4d8ef033a5fbb155fe62e9c78e
ToppCell	(2)_NK/T-(210)_NKT_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	TPST2 TSPOAP1 SQLE FRY HEATR9	1.02e-04	189	109	5	fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell	PCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	AQP3 CD38 LTA PREX1 IL26	1.02e-04	189	109	5	620d5a71b8cb6288540e2d2d848b9d4d66c1226f
ToppCell	(2)_NK/T-(21)_NKT_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	TPST2 TSPOAP1 SQLE FRY HEATR9	1.02e-04	189	109	5	b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AQP3 ABCC6 EVA1A TMC5	1.02e-04	189	109	5	926b5fa3064b501a57ba78583e8af33532add455
ToppCell	metastatic_Lymph_Node-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	TPST2 MEI1 AQP3 CD38 UBE2S	1.04e-04	190	109	5	5ec49cc7692053c1a525ca9137c996ccd2794e1c
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 NR4A3 ITPR3 CD22 LTA	1.04e-04	190	109	5	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AQP3 ABCC6 EVA1A TMC5	1.04e-04	190	109	5	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 NR4A3 ITPR3 CD22 LTA	1.04e-04	190	109	5	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 NR4A3 ITPR3 CD22 LTA	1.04e-04	190	109	5	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NR4A3 SLC1A5 HEATR9 UBE2S PREX1	1.07e-04	191	109	5	04faa7d2237e45418611153294eb6f7bb690cbde
ToppCell	wk_08-11-Epithelial-PNS-SST+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NRCAM ARHGDIG SLC18A3 SVOP CNR1	1.07e-04	191	109	5	df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCell	T_cells-Central_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	GPR155 PDE3B AQP3 LTA MCOLN3	1.07e-04	191	109	5	25dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRCAM EVA1A CD38 CYP7B1 FXYD1	1.10e-04	192	109	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 NR4A3 NAA25 CD38 UBE2S	1.12e-04	193	109	5	89c63dd5d97fbd92ea308405b7e8e630dda5158d
ToppCell	COVID-19_Severe-Plasmablast\|COVID-19_Severe / disease group, cell group and cell class	MEI1 AQP3 SLC2A5 CD38 BUB1	1.12e-04	193	109	5	8074bcede261b85f9ae03ee372bd6d4b40384537
ToppCell	11.5-Airway-Immune-Hematopoietic,_T_Cells\|Airway / Age, Tissue, Lineage and Cell class	TNFRSF11A AQP3 LTA PREX1 IL26	1.12e-04	193	109	5	7c14bc481ed38378b9e6a85f768a1e526c5997e6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LRRK2 NR4A3 NAA25 CD38 UBE2S	1.12e-04	193	109	5	7842f29c16fe3a289ed3861fa570430142d2363f
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EARS2 LRRK2 ITPR3 NEK3 HEATR6	1.15e-04	194	109	5	df835578d86a49ae5af5632152fbab9548c0a448
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EARS2 LRRK2 ITPR3 NEK3 HEATR6	1.15e-04	194	109	5	0715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCell	PBMC-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	STRBP SLC2A5 CD22 CD38 BUB1	1.15e-04	194	109	5	7dbedbdece4271e10134c9338c85cb3e04484c75
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	NRCAM HEATR1 URB2 NAA25 SVIL	1.15e-04	194	109	5	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	(7)_Epithelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LRRK2 AQP3 ITPR3 EVA1A TMC5	1.15e-04	194	109	5	413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell	Severe-CD4+_T\|World / Disease group and Cell class	AQP3 FRY SVIL LTA FXYD1	1.15e-04	194	109	5	2ad888f78765ecfb8d1ea978c75c90fa3030509a
ToppCell	PBMC-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	STRBP SLC2A5 CD22 CD38 BUB1	1.15e-04	194	109	5	bd2c53fb064edfec76abe56a9ffaced0bda32ab0
ToppCell	AT2\|World / shred by cell class for parenchyma	LRRK2 AQP3 ITPR3 EVA1A TMC5	1.15e-04	194	109	5	e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EARS2 LRRK2 ITPR3 NEK3 HEATR6	1.15e-04	194	109	5	a4f7cd507eba40985d82635bbae28c7f5703f883
ToppCell	356C-Epithelial_cells\|356C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AQP3 ITPR3 EVA1A TMC5	1.18e-04	195	109	5	d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP SLC1A5 HEATR6 CD22 CD38	1.18e-04	195	109	5	d77423d0ec64b397c6d1eec181c5fc0acaa92d63
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MEI1 TMC3 CFAP54 CD38 IL26	1.18e-04	195	109	5	0b0615553b9a1b60d666d074ce4260919e2d5642
ToppCell	(7)_Epithelial-A_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LRRK2 AQP3 ITPR3 EVA1A TMC5	1.18e-04	195	109	5	c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell	Control-Lymphoid-CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	PDE3B AQP3 CFAP54 LTA FXYD1	1.18e-04	195	109	5	8679a122fe796b1eddef82460e985b3fd3b3a2a5
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAYN AQP3 LTA SLC38A3 IL26	1.18e-04	195	109	5	69201b1172bcf0999c726516e4d30863afceab0b
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP SLC1A5 HEATR6 CD22 CD38	1.18e-04	195	109	5	f5bf4797972185afa76638293166abd536e5472f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SQLE LRRK2 ITPR3 EVA1A TMC5	1.21e-04	196	109	5	a6a52cafd7c9994bc3d2f68b15a1491cd96ef908
ToppCell	normal_Pleural_Fluid-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	TPST2 AQP3 CD38 BUB1 UBE2S	1.21e-04	196	109	5	0ff8cfb209063a8b217df6690ac1dec89004593f
ToppCell	COVID-19-Lymphoid-CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	AQP3 FRY SVIL LTA FXYD1	1.21e-04	196	109	5	28515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCell	proximal-Hematologic-Interstitial_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSC2 IL18BP ADGRE4P CD68 TAS2R50	1.21e-04	196	109	5	b6a858c43fef42cd724d56c8283e954bcb546106
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LRRK2 AQP3 ITPR3 TMC5 CNR1	1.21e-04	196	109	5	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	droplet-Marrow-BM-1m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP SLC1A5 CD22 BUB1 UBE2S	1.21e-04	196	109	5	ef1482f83872af72a55b6c5b5a1491e6f7f44dd7
ToppCell	tumor_Lung-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	TPST2 MEI1 AQP3 SLC1A5 CD38	1.21e-04	196	109	5	1f63dba9d226e4a42d9bee7258580a1e547c0e92
ToppCell	proximal-3-Hematologic-Interstitial_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSC2 IL18BP ADGRE4P CD68 TAS2R50	1.21e-04	196	109	5	d8c9cb86233470c3044865ad05ea202e294d80bf
ToppCell	proximal-Hematologic-Interstitial_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSC2 IL18BP ADGRE4P CD68 TAS2R50	1.21e-04	196	109	5	9d4d8ffe9d30de7d1dc33d261bc2aaf4189ad86c
ToppCell	Severe-CD4+_T\|Severe / Disease group and Cell class	AQP3 FRY SVIL LTA FXYD1	1.21e-04	196	109	5	576e0aa2ae146a86201dea21097ffe1c867956e7
ToppCell	356C-Epithelial_cells-Epithelial-B_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AQP3 ITPR3 EVA1A TMC5	1.24e-04	197	109	5	06ed8f293d4ee89f14dc2f43d6cae93bbc02508a
Drug	mag-fura-2	TRPM6 ITPR3 BTC ATP2A1 ATP2A2	8.45e-07	37	108	5	CID000123839
Drug	Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	PDE3B DSC2 AQP3 LYST FRY LRRC14 DNAH9 SLC2A11	4.58e-06	197	108	8	3859_UP
Drug	AC1MMLID	ITPR3 CD22 FXYD1 ATP2A1 ATP2A2 SLC38A3	5.07e-06	92	108	6	CID000013245
Disease	upper aerodigestive tract neoplasm	HEATR1 BIRC6 CHRNA5 NAA25 SVIL CYP7B1 SLC38A3	2.75e-05	246	104	7	EFO_0004284
Disease	phosphatidylcholine 40:6 measurement	TMTC4 TMC5 DNAH9	2.79e-05	17	104	3	EFO_0010389
Disease	Brody myopathy (implicated_via_orthology)	ATP2A1 ATP2A2	3.68e-05	3	104	2	DOID:0050692 (implicated_via_orthology)
Disease	type 1 diabetes mellitus (is_implicated_in)	ITPR3 BTC CD38 LTA	2.37e-04	85	104	4	DOID:9744 (is_implicated_in)
Disease	Osteitis Deformans	TNFRSF11A NUP205	4.36e-04	9	104	2	C0029401
Disease	Anxiety States, Neurotic	CHRNA5 UCN CNR1	5.07e-04	44	104	3	C0376280
Disease	Anxiety Disorders	CHRNA5 UCN CNR1	5.07e-04	44	104	3	C0003469
Disease	Anxiety neurosis (finding)	CHRNA5 UCN CNR1	5.07e-04	44	104	3	C1279420
Disease	linguistic error measurement, specific language impairment	TPST2 RTL1	5.44e-04	10	104	2	EFO_0007798, EFO_1001510
Disease	osteitis deformans	TNFRSF11A NUP205	9.36e-04	13	104	2	EFO_0004261
Disease	N-acetyltaurine measurement	SLC38A3 CNR1	9.36e-04	13	104	2	EFO_0020023
Disease	dystonia (is_implicated_in)	TSPOAP1 MECR	1.09e-03	14	104	2	DOID:543 (is_implicated_in)
Disease	Arthritis, Psoriatic	CD68 LTA	1.09e-03	14	104	2	C0003872
Disease	infant head circumference	STRBP PREX1	1.25e-03	15	104	2	EFO_0004577
Disease	fish consumption measurement	LAYN NAA25 TMTC4	1.52e-03	64	104	3	EFO_0010139
Disease	emphysema pattern measurement	CHRNA5 SVIL	2.02e-03	19	104	2	EFO_0005850
Disease	type 2 diabetes mellitus (is_implicated_in)	BTC CD38 LTA CNR1	3.19e-03	171	104	4	DOID:9352 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QGRQLLLVSLTRLCH	URB2	1051	Q14146
RVLRHCDILTGVLTL	ERC2-IT1	41	O76042
RRCLRANLLVLLTVV	SLC1A5	46	Q15758
SVVQCLHILSSLRLI	CFAP54	216	Q96N23
RIGLKLIDILLRNCA	BIRC6	3391	Q9NR09
IRALRNRLIVLLLEC	BUB1	1066	O43683
RRALLCLLLVLGIAF	ABCA10	771	Q8WWZ4
IIGTCAHLIRAKLLR	GPR32	231	O75388
CLLNRQVRLIILSVI	ADGRE4P	436	Q86SQ3
IIQTKALQVGCLLRL	AP2A1	931	O95782
IQLLKIGSAIQRLRC	CRBN	296	Q96SW2
NGALCRLLLLTLAIL	DSC2	11	Q02487
LVRILLLAACISFVL	ATP2A1	61	O14983
RAQLCLGVSILVLIL	CD38	21	P28907
LVLLTLATLCTRLHR	TP53I13	321	Q8NBR0
LLRALGELRQRCAIL	TSPOAP1	126	O95153
LVLTLAALVIRISCH	EVA1A	46	Q9H8M9
SRLLLLLCIFLGTLR	PCDHGA11	11	Q9Y5H2
LLRLTRTLLGIIDCV	ITPR3	881	Q14573
LELLRSGVIVRLAQC	NUP205	1571	Q92621
LGLLALVLIAFCIIR	CD68	331	P34810
HTRLLQICLLLGVLV	PCDHGA4	41	Q9Y5G9
GNLLIILAICADIRL	OR1A2	41	Q9Y585
CLVSLILCIRSVIRG	MCOLN3	296	Q8TDD5
ILCIRSVIRGLQLQQ	MCOLN3	301	Q8TDD5
ILILLIVCFIRRNKG	NRCAM	1181	Q92823
GDQQLTRHVLLCLLL	GPR155	651	Q7Z3F1
TRHVLLCLLLIIGLF	GPR155	656	Q7Z3F1
VLLLCAHVVTLLVRA	IL18BP	16	O95998
ALQAVLLAVLLVGLR	LAYN	6	Q6UX15
LLHLCRLTIRNQLLT	ASB17	256	Q8WXJ9
VRICLGAVILIILAG	GP6	271	Q9HCN6
GRLKVTLLECSRLLI	PDZD8	321	Q8NEN9
RLLLVLSCVGLLLTL	PDE3B	196	Q13370
LCIARAVLRNSKIIL	ABCC11	1286	Q96J66
VSLRTQICQALIHLL	HEATR6	1066	Q6AI08
ILFILGILIVLSRRC	FXYD1	46	O00168
ALALGEVLRLNRCLV	LRRC74A	291	Q0VAA2
HTSLRLLRQELVVLC	LRRK2	1911	Q5S007
VVTVLGNCLIVLLIR	OR2F1	36	Q13607
GNCLIVLLIRLDSRL	OR2F1	41	Q13607
GNCLIVLLIRLDSRL	OR2F2	41	O95006
LLSRGIVARLVQKCL	NEK3	251	P51956
LIRGHFLLILQRLLV	MEI1	881	Q5TIA1
CGSLLALVHVVLILR	OR2A5	151	Q96R48
VACDLLRRIIRILNL	COG5	171	Q9UP83
LRLLLLVQLVAGRCG	CHRNA5	11	P30532
LVRILLLAACISFVL	ATP2A2	61	P16615
RLIQGRILLLTICAA	SLC2A11	6	Q9BYW1
AQLLELLRLALCARV	ARHGDIG	11	Q99819
IIGTCAHLIRAKLLR	GPR32P1	231	Q8NGA4
REVLLCVLVFLSLGL	SQLE	26	Q14534
ILRCGLLLVTLSLAI	IL26	6	Q9NPH9
VLENLLVLCVILHSR	CNR1	131	P21554
QSIRLLEALLAICLH	LYST	1101	Q99698
AALLLLALCLLVRRT	CYP7B1	26	O75881
LIKDGLSCLIVLLQR	HEATR1	296	Q9H583
ELILTLCDLIRRGQL	MECR	326	Q9BV79
GRLTVLLQEICNLLI	DNAH9	356	Q9NYC9
LRVHQLGCEVVVLLL	FRY	1196	Q5TBA9
TVRCLRDTVLLLHGL	ATRIP	716	Q8WXE1
LLALALGLVILHCVV	BTC	16	P35070
LAILILAICGLKLQR	CD22	696	P20273
LRIQLVLGACSIGLI	OR10J1	151	P30954
VLILLLTLCGRNKLE	OR2B8P	161	P59922
LLVLLLLALGVRAVR	MUC3B	1151	Q9H195
ALVELRKICTLGLQR	NR4A3	586	Q92570
TPRQLLVALACLLLS	FREM3	11	P0C091
ALAAILVLLRVRQCL	RTL1	1091	A6NKG5
VILLGTLIFLVCHLL	TAS2R50	131	P59544
LLFICVGRNVLTLLL	SVOP	416	Q8N4V2
QRRLVLVIVCVALLL	SLC18A3	31	Q16572
VIHLLLCQLRVLEVG	POLR1A	116	O95602
ICLRIIANILVLLSL	TMC3	316	Q7Z5M5
RHVLIAVGLLTCINL	SLC38A3	406	Q99624
ILLQSCTGLVTHRLL	SVIL	21	O95425
FIITTLALLRIILLC	TAS2R3	46	Q9NYW6
LAIRRCVLGALQVLL	TMEM191B	276	P0C7N4
ALAIRRCVLGALQVL	TMEM191C	276	A6NGB0
CLARALLRKTQILIL	ABCC6	1411	O95255
CAVFVVELLGRRLLL	SLC2A5	331	P22732
RRLLLLLGFSICLIA	SLC2A5	341	P22732
QLRLRLCVLNEILGT	PREX1	46	Q8TCU6
LLHLLVTIRDVLLTC	SHOC1	661	Q5VXU9
RANGLKSCVIVLRIL	STRBP	211	Q96SI9
LSQEELLSCLLRLGL	OCSTAMP	291	Q9BR26
VPRLCLTLANLNRVI	PEX11A	81	O75192
IAIVLTLSCHILLRR	ABCC12	356	Q96J65
CVARALLRNSKIILL	ABCC12	1266	Q96J65
TRFLICRDLLILQQL	NUP160	726	Q12769
RILLLRQGHICRLQD	EARS2	401	Q5JPH6
LLRQALAECLGTLIL	AQP3	21	Q92482
RALCVIALLLALLGL	CLDN9	81	O95484
CRRQIIRALCLLLLL	WFDC1	11	Q9HC57
VLGILFINTLRCVLR	TMTC4	446	Q5T4D3
RRVLLAAGCALVLVL	TPST2	6	O60704
RVCGTTLHLLLLGLL	LTA	11	P01374
ILLSHVGLLLRRLCC	TRPM6	1106	Q9BX84
RALQLALDQLCLLGL	MEX3A	36	A1L020
VGLICLLLILHRSVS	TMC4	261	Q7Z404
AILGCLNKHVIRALI	HEATR9	206	A2RTY3
LTINILRGQILIALC	TMPRSS12	326	Q86WS5
LRGQILIALCFVILL	TMPRSS12	331	Q86WS5
LLLTSIVLRILCSLV	TMEM168	126	Q9H0V1
IVLRILCSLVERISG	TMEM168	131	Q9H0V1
ELGIRHVLLTIKCLL	UBE2S	106	Q16763
RCLLLLVAIVGFQVL	TOR4A	121	Q9NXH8
RLQALSHLVSVLLLC	SLC30A5	236	Q8TAD4
IRNIFLKISIIGILC	TMC5	696	Q6UXY8
KHLLGRLCQITRSLL	TRANK1	2126	O15050
RAALLAALLLLVQLC	UCN	6	P55089
LLCALLARLQVALQI	TNFRSF11A	16	Q9Y6Q6
KLLGILVLCLHTRGI	PSORS1C2	6	Q9UIG4
VLALSHTVLVLLLLC	TMEM272	156	A0A1B0GTI8
RRVLTAILILGLLLC	KEL	46	P23276
VALLQLLDAGCLRRV	LRRC14	211	Q15048
RLKLCVLVLILLHTV	NALF1	416	B1AL88
LQQHLCVVQLTRLLG	NAA25	411	Q14CX7