Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPV1 GRIN2A RYR1 RYR3 ITPR3

4.19e-06311585GO:0099604
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

TRPV1 RYR1 RYR3 ITPR3

1.06e-05181584GO:0015278
GeneOntologyMolecularFunctioncalcium channel activity

TRPV1 GRIN2A PANX3 RYR1 RYR3 ITPR3 SEC61A1

7.58e-051291587GO:0005262
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

TRPV1 RYR1 RYR3 ITPR3

1.29e-04331584GO:0005217
GeneOntologyMolecularFunctiondiglucosylglycerate octanoyltransferase activity

CRAT CROT

1.86e-0431582GO:0016414
GeneOntologyMolecularFunctioncarnitine O-octanoyltransferase activity

CRAT CROT

1.86e-0431582GO:0008458
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPV1 GRIN2A PANX3 RYR1 RYR3 ITPR3 SEC61A1

2.02e-041511587GO:0015085
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRB2 TRPV1 TTYH2 GRIN2A PANX3 RYR1 RYR3 ITPR3 BSND PIEZO2 SCN2A SEC61A1

3.01e-0445915812GO:0005216
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

3.69e-0441582GO:0005219
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

4.86e-04821585GO:1990756
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRB2 TRPV1 TTYH2 GRIN2A RYR1 RYR3 ITPR3

8.83e-041931587GO:0015276
GeneOntologyMolecularFunctioncarnitine O-acyltransferase activity

CRAT CROT

9.14e-0461582GO:0016406
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPP ALPG

9.14e-0461582GO:0004035
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

9.14e-0461582GO:0048763
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

9.40e-04551584GO:0042974
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

9.51e-04951585GO:0140767
GeneOntologyMolecularFunctionchannel activity

GABRB2 TRPV1 TTYH2 GRIN2A PANX3 RYR1 RYR3 ITPR3 BSND PIEZO2 SCN2A SEC61A1

9.84e-0452515812GO:0015267
GeneOntologyMolecularFunctionligand-gated channel activity

GABRB2 TRPV1 TTYH2 GRIN2A RYR1 RYR3 ITPR3

9.95e-041971587GO:0022834
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRB2 TRPV1 TTYH2 GRIN2A PANX3 RYR1 RYR3 ITPR3 BSND PIEZO2 SCN2A SEC61A1

1.00e-0352615812GO:0022803
GeneOntologyMolecularFunctiongated channel activity

GABRB2 TRPV1 TTYH2 GRIN2A RYR1 RYR3 ITPR3 PIEZO2 SCN2A

1.40e-033341589GO:0022836
GeneOntologyBiologicalProcesssynaptic membrane adhesion

NRG1 MAGI2 MDGA1 CDH6 CDH9

1.73e-05421595GO:0099560
GeneOntologyBiologicalProcesssynapse assembly

GABRB2 NRG1 PDGFB USP9X PCLO MAGI2 DOCK7 ADGRL2 MDGA1 CDH9 ADGRL3

2.81e-0530815911GO:0007416
GeneOntologyBiologicalProcessresponse to nutrient levels

CYP1A1 TRPV1 DSC2 PARP2 LRRK2 F5 FBXO22 GCLC SCD AGL CPEB4 NPRL3 BCL10 ULK1 MLST8

3.36e-0556615915GO:0031667
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.92e-05471605GO:0031462
GeneOntologyCellularComponentZ disc

FLNB NEBL NEB RYR1 RYR3 FBXO22 NOS1

1.66e-041511607GO:0030018
GeneOntologyCellularComponentsomatodendritic compartment

PCSK2 FLNB TRPV1 PDGFB FAT3 PCLO LRRK2 CNTNAP3 MPDZ GRIN2A DCTN1 ITPR3 MAGI2 SNCAIP FCGR2B CPEB4 ULK1 ARHGEF2 MDGA1 NOS1 CDH9 EPHA8

1.74e-04122816022GO:0036477
GeneOntologyCellularComponentmyofibril

FLNB NEBL NEB RYR1 RYR3 FBXO22 NOS1 ALPP ALPG

2.62e-042731609GO:0030016
GeneOntologyCellularComponentI band

FLNB NEBL NEB RYR1 RYR3 FBXO22 NOS1

2.96e-041661607GO:0031674
GeneOntologyCellularComponentdendrite

PCSK2 TRPV1 PDGFB FAT3 PCLO LRRK2 MPDZ GRIN2A ITPR3 MAGI2 FCGR2B CPEB4 ARHGEF2 MDGA1 NOS1 CDH9 EPHA8

3.21e-0485816017GO:0030425
GeneOntologyCellularComponentdendritic tree

PCSK2 TRPV1 PDGFB FAT3 PCLO LRRK2 MPDZ GRIN2A ITPR3 MAGI2 FCGR2B CPEB4 ARHGEF2 MDGA1 NOS1 CDH9 EPHA8

3.29e-0486016017GO:0097447
GeneOntologyCellularComponentcontractile muscle fiber

FLNB NEBL NEB RYR1 RYR3 FBXO22 NOS1 ALPP ALPG

4.08e-042901609GO:0043292
GeneOntologyCellularComponentSec61 translocon complex

SEC61A2 SEC61A1

5.73e-0451602GO:0005784
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 RYR3 ITPR3 AGL NOS1

5.80e-04881605GO:0016529
GeneOntologyCellularComponenttranslocon complex

SEC61A2 SEC61A1

8.56e-0461602GO:0071256
GeneOntologyCellularComponentaxon

NRG1 USP9X PCLO LRRK2 CNTNAP3 EXOC3 GRIN2A DCTN1 SCN2A CPEB4 DOCK7 ULK1 MDGA1 NOS1 CDH9 ADGRL3

1.37e-0389116016GO:0030424
GeneOntologyCellularComponentsecretory vesicle

PCSK2 ABCC4 KLK6 ANPEP PDGFB ACR PRAMEF15 LRRK2 EXOC3 GRIN2A PRAMEF4 F5 ITPR3 CFD SNCAIP AGL KLK1 NOS1 PRAMEF11 VEGFB

1.37e-03124616020GO:0099503
GeneOntologyCellularComponentGABA-ergic synapse

GABRB2 NRG1 TRPV1 PCLO MAGI2 MDGA1

1.67e-031641606GO:0098982
GeneOntologyCellularComponentplatelet alpha granule lumen

PDGFB F5 CFD VEGFB

1.74e-03671604GO:0031093
GeneOntologyCellularComponentsarcoplasm

RYR1 RYR3 ITPR3 AGL NOS1

1.85e-031141605GO:0016528
GeneOntologyCellularComponentsecretory granule

PCSK2 ABCC4 KLK6 ANPEP PDGFB ACR PRAMEF15 EXOC3 PRAMEF4 F5 ITPR3 CFD AGL KLK1 NOS1 PRAMEF11 VEGFB

2.01e-03101416017GO:0030141
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

2.02e-0391602GO:0030314
DomainRIH_assoc-dom

RYR1 RYR3 ITPR3

1.06e-0561533IPR013662
DomainIns145_P3_rec

RYR1 RYR3 ITPR3

1.06e-0561533PF08709
DomainRIH_assoc

RYR1 RYR3 ITPR3

1.06e-0561533PF08454
DomainRIH_dom

RYR1 RYR3 ITPR3

1.06e-0561533IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3 ITPR3

1.06e-0561533IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3 ITPR3

1.06e-0561533IPR015925
Domain-

RYR1 RYR3 ITPR3

1.06e-05615331.25.10.30
DomainRYDR_ITPR

RYR1 RYR3 ITPR3

1.06e-0561533PF01365
DomainPRAME_family

PRAMEF25 PRAMEF15 PRAMEF4 PRAMEF27

1.52e-05191534IPR026271
DomainCadherin_C

DSC2 DSC3 CDH6 CDH9

4.79e-05251534PF01049
DomainCadherin_cytoplasmic-dom

DSC2 DSC3 CDH6 CDH9

4.79e-05251534IPR000233
DomainMIR

RYR1 RYR3 ITPR3

6.20e-05101533PF02815
DomainMIR_motif

RYR1 RYR3 ITPR3

6.20e-05101533IPR016093
DomainMIR

RYR1 RYR3 ITPR3

6.20e-05101533PS50919
DomainMIR

RYR1 RYR3 ITPR3

6.20e-05101533SM00472
DomainSecY_su_dom

SEC61A2 SEC61A1

6.67e-0521532IPR023201
DomainSECY_1

SEC61A2 SEC61A1

6.67e-0521532PS00755
DomainSECY_2

SEC61A2 SEC61A1

6.67e-0521532PS00756
Domain-

SEC61A2 SEC61A1

6.67e-05215321.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A2 SEC61A1

6.67e-0521532IPR019561
DomainSecY_CS

SEC61A2 SEC61A1

6.67e-0521532IPR030659
DomainPlug_translocon

SEC61A2 SEC61A1

6.67e-0521532PF10559
DomainSecY

SEC61A2 SEC61A1

6.67e-0521532PF00344
DomainSecY/SEC61-alpha

SEC61A2 SEC61A1

6.67e-0521532IPR002208
DomainCatenin_binding_dom

DSC2 DSC3 CDH6 CDH9

8.77e-05291534IPR027397
Domain-

DSC2 DSC3 CDH6 CDH9

8.77e-052915344.10.900.10
DomainGalactose-bd-like

PCSK2 PITHD1 CNTNAP3 F5 NPRL3 EPHA8

1.23e-04941536IPR008979
DomainLatrophilin

ADGRL2 ADGRL3

1.99e-0431532PF02354
DomainRyanodine_rcpt

RYR1 RYR3

1.99e-0431532IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR3

1.99e-0431532IPR009460
DomainRyR

RYR1 RYR3

1.99e-0431532PF02026
DomainRR_TM4-6

RYR1 RYR3

1.99e-0431532PF06459
DomainGPCR_2_latrophilin_rcpt_C

ADGRL2 ADGRL3

1.99e-0431532IPR003334
DomainRyan_recept

RYR1 RYR3

1.99e-0431532IPR013333
DomainNebulin

NEBL NEB

3.96e-0441532PF00880
DomainAlk_phosphatase

ALPP ALPG

3.96e-0441532PF00245
DomainAlkaline_phosphatase_AS

ALPP ALPG

3.96e-0441532IPR018299
DomainNEBULIN

NEBL NEB

3.96e-0441532PS51216
DomainNEBU

NEBL NEB

3.96e-0441532SM00227
DomainNebulin

NEBL NEB

3.96e-0441532IPR013998
DomainAlkaline_phosphatase

ALPP ALPG

3.96e-0441532IPR001952
DomainNebulin_repeat

NEBL NEB

3.96e-0441532IPR000900
DomainalkPPc

ALPP ALPG

3.96e-0441532SM00098
DomainALKALINE_PHOSPHATASE

ALPP ALPG

3.96e-0441532PS00123
DomainGal_Lectin

ADGRL2 ADGRL3

6.56e-0451532PF02140
DomainINTEGRASE

GIN1 NYNRIN

6.56e-0451532PS50994
DomainIntegrase_cat-core

GIN1 NYNRIN

6.56e-0451532IPR001584
DomainGPCR_2_latrophilin

ADGRL2 ADGRL3

6.56e-0451532IPR003924
DomainLectin_gal-bd_dom

ADGRL2 ADGRL3

6.56e-0451532IPR000922
DomainSUEL_LECTIN

ADGRL2 ADGRL3

6.56e-0451532PS50228
DomainCarn_acyl_trans

CRAT CROT

1.36e-0371532IPR000542
DomainDesmosomal_cadherin

DSC2 DSC3

1.36e-0371532IPR009122
DomainCadherin_pro

DSC2 DSC3

1.36e-0371532PF08758
DomainCarn_acyltransf

CRAT CROT

1.36e-0371532PF00755
DomainACYLTRANSF_C_1

CRAT CROT

1.36e-0371532PS00439
DomainPD_growth_factor_CS

PDGFB VEGFB

1.36e-0371532IPR023581
DomainACYLTRANSF_C_2

CRAT CROT

1.36e-0371532PS00440
DomainCadherin_pro

DSC2 DSC3

1.81e-0381532SM01055
DomainCadherin_pro_dom

DSC2 DSC3

1.81e-0381532IPR014868
DomainCadherin_CS

DSC2 DSC3 FAT3 CDH6 CDH9

2.04e-031091535IPR020894
DomainBEACH

WDR81 WDFY4

2.31e-0391532PS50197
DomainBeach

WDR81 WDFY4

2.31e-0391532PF02138
Domain-

WDR81 WDFY4

2.31e-03915321.10.1540.10
DomainPDGF_1

PDGFB VEGFB

2.31e-0391532PS00249
DomainBeach

WDR81 WDFY4

2.31e-0391532SM01026
DomainPDGF

PDGFB VEGFB

2.31e-0391532SM00141
DomainBEACH_dom

WDR81 WDFY4

2.31e-0391532IPR000409
DomainPDGF

PDGFB VEGFB

2.31e-0391532PF00341
DomainPDGF_2

PDGFB VEGFB

2.31e-0391532PS50278
DomainPDGF/VEGF_dom

PDGFB VEGFB

2.31e-0391532IPR000072
DomainCADHERIN_1

DSC2 DSC3 FAT3 CDH6 CDH9

2.39e-031131535PS00232
DomainCadherin

DSC2 DSC3 FAT3 CDH6 CDH9

2.39e-031131535PF00028
DomainIon_trans_dom

TRPV1 RYR1 RYR3 ITPR3 SCN2A

2.48e-031141535IPR005821
DomainIon_trans

TRPV1 RYR1 RYR3 ITPR3 SCN2A

2.48e-031141535PF00520
DomainCADHERIN_2

DSC2 DSC3 FAT3 CDH6 CDH9

2.48e-031141535PS50268
Domain-

DSC2 DSC3 FAT3 CDH6 CDH9

2.48e-0311415352.60.40.60
DomainCA

DSC2 DSC3 FAT3 CDH6 CDH9

2.57e-031151535SM00112
DomainCadherin-like

DSC2 DSC3 FAT3 CDH6 CDH9

2.67e-031161535IPR015919
DomainCadherin

DSC2 DSC3 FAT3 CDH6 CDH9

2.88e-031181535IPR002126
Domain-

PCSK2 CNTNAP3 F5 EPHA8

3.04e-037315342.60.120.260
DomainGAIN_dom_N

ADGRL2 ADGRL3

3.49e-03111532IPR032471
DomainGAIN

ADGRL2 ADGRL3

3.49e-03111532PF16489
DomainOxysterol-bd_CS

OSBPL3 OSBPL10

4.17e-03121532IPR018494
DomainOxysterol_BP

OSBPL3 OSBPL10

4.17e-03121532PF01237
DomainOxysterol-bd

OSBPL3 OSBPL10

4.17e-03121532IPR000648
DomainOSBP

OSBPL3 OSBPL10

4.17e-03121532PS01013
DomainOLF

ADGRL2 ADGRL3

4.90e-03131532PF02191
DomainOLF

ADGRL2 ADGRL3

4.90e-03131532PS51132
DomainOlfac-like_dom

ADGRL2 ADGRL3

4.90e-03131532IPR003112
DomainOLF

ADGRL2 ADGRL3

4.90e-03131532SM00284
DomainTRYPSIN_SER

KLK6 ACR CFD KLK1

6.41e-03901534IPR033116
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 RYR3 ITPR3

3.88e-074161322100703
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HDAC9 MAN2B2 PTPN23 WDFY4 SLC45A4 FAN1 PER3 ALMS1 OSBPL3 N4BP2 CPEB4 WDR35 PRDM16

5.67e-074931611315368895
Pubmed

Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.

CDX2 DSC2 DSC3

9.67e-075161322438068
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR3 ITPR3

1.93e-066161323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR3 ITPR3

1.93e-066161325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR3 ITPR3

1.93e-066161320519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR3 ITPR3

1.93e-066161316844763
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.02e-0620161426694250
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

3.03e-0622161431729367
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR3 ITPR3

3.36e-067161311860456
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

FAT3 MDGA1 CDH6 CDH9 PLXNA2 EPHA8

4.32e-0691161628558017
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

5.19e-0625161437451217
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR3 ITPR3

5.36e-068161319033399
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

RALGAPA1 IRS4 USP9X MPDZ NCKAP5L LRCH1 ALMS1 NYNRIN CPEB4 DOCK7 ARHGEF2

8.11e-064461611124255178
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

8.31e-0628161425089626
Pubmed

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

IRS4 USP9X LRRK2 MCM4 AGL

1.04e-0562161526508657
Pubmed

USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription.

IRS4 USP9X FBXO22

1.56e-0511161333558705
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

KLK6 MAN2B2 DSC2 NEBL PRAMEF15 GRIN2A IDE PRAMEF4 SULT1C4 OGDH DCTN1 ADAR MAGI2 GCLC OSBPL3 PLXNA2 PRAMEF11 DNPEP

1.96e-0512421611830973865
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.07e-0535161419389355
Pubmed

Purification and partial sequencing of human placental alkaline phosphatase.

ALPP ALPG

2.13e-05216126651840
Pubmed

Reciprocal signalling between NR2 subunits of the NMDA receptor and neuregulin1 and their role in schizophrenia.

NRG1 GRIN2A

2.13e-052161221371516
Pubmed

Changes in actin dynamics and F-actin structure both in synaptoneurosomes of LRRK2(R1441G) mutant mice and in primary human fibroblasts of LRRK2(G2019S) mutation carriers.

KHDRBS2 LRRK2

2.13e-052161225301747
Pubmed

Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.

KHDRBS2 LRRK2

2.13e-052161222342962
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.13e-05216129489997
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

2.13e-052161212640042
Pubmed

Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.

ALPP ALPG

2.13e-052161211124260
Pubmed

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

ALPP ALPG

2.13e-05216123461452
Pubmed

Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells.

ALPP ALPG

2.13e-05216123459156
Pubmed

Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein.

ALPP ALPG

2.13e-05216121730777
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

2.13e-052161214592949
Pubmed

ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism.

METTL3 ADAR

2.13e-052161233509238
Pubmed

LRRK2 expression is enriched in the striosomal compartment of mouse striatum.

KHDRBS2 LRRK2

2.13e-052161222850484
Pubmed

Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA.

ALPP ALPG

2.13e-05216123001717
Pubmed

Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.

ADGRL2 ADGRL3

2.13e-052161230792275
Pubmed

Variable phenotype of del45-55 Becker patients correlated with nNOSμ mislocalization and RYR1 hypernitrosylation.

RYR1 NOS1

2.13e-052161222589245
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

2.13e-05216129799464
Pubmed

Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution.

ALPP ALPG

2.13e-05216123042787
Pubmed

Novel IgCAM, MDGA1, expressed in unique cortical area- and layer-specific patterns and transiently by distinct forebrain populations of Cajal-Retzius neurons.

NRG1 MDGA1

2.13e-052161216959869
Pubmed

Substrate specificity of human kallikreins 1 and 6 determined by phage display.

KLK6 KLK1

2.13e-052161218359858
Pubmed

Latrophilin GPCR signaling mediates synapse formation.

ADGRL2 ADGRL3

2.13e-052161233646123
Pubmed

Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

NEBL NEB

2.13e-052161219851499
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

2.13e-052161217118445
Pubmed

Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation.

NRG1 TRPV1

2.13e-052161221949864
Pubmed

Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme.

ALPP ALPG

2.13e-05216123422741
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

2.13e-052161211500519
Pubmed

Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy.

TRPV1 NOS1

2.13e-052161223202294
Pubmed

The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.

KHDRBS2 LRRK2

2.13e-052161226811536
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A2 SEC61A1

2.13e-052161218480044
Pubmed

Mutation of a single amino acid converts germ cell alkaline phosphatase to placental alkaline phosphatase.

ALPP ALPG

2.13e-05216121939159
Pubmed

Non-motor and motor features in LRRK2 transgenic mice.

KHDRBS2 LRRK2

2.13e-052161223936174
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

2.13e-052161212565913
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.13e-05216129192302
Pubmed

RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis.

METTL3 ADAR

2.13e-052161236077054
Pubmed

ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer.

ADAR SCD

2.13e-052161237208334
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

2.13e-05216127556644
Pubmed

Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase.

ALPP ALPG

2.13e-05216122153284
Pubmed

14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening.

KHDRBS2 LRRK2

2.13e-052161226546614
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

2.13e-052161215894801
Pubmed

Molecular cloning and sequence analysis of human placental alkaline phosphatase.

ALPP ALPG

2.13e-05216123512548
Pubmed

ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.

LRRK2 ULK1

2.13e-052161227023913
Pubmed

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors.

RYR1 ITPR3

2.13e-052161221150295
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

2.13e-05216129817784
Pubmed

Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.

NEB RYR1

2.13e-052161238520674
Pubmed

Cdx2 homeodomain protein regulates the expression of MOK, a member of the mitogen-activated protein kinase superfamily, in the intestinal epithelial cells.

MOK CDX2

2.13e-052161215327990
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RALGAPA1 PITHD1 FLNB RIOK1 DSC2 DSC3 USP9X EXOC3 MPDZ PTPN23 MCM4 DOCK7 ADGRL2

2.80e-057081611339231216
Pubmed

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.

CDX2 ALPP ALPG

3.41e-0514161336639541
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

ZCCHC12 PEG10 PRAMEF15 KHDRBS2 PRAMEF4 ADAR SUPT6H CPEB4 PRAMEF11

3.73e-05347161916033648
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RALGAPA1 FLNB USP9X PCLO SCRN1 GRIN2A OGDH DCTN1 MAGI2 NWD2 SUGP2 SCN2A CPEB4 DOCK7 OSBPL10 PACS2 ARHGEF2 NOS1 DNPEP

3.77e-0514311611937142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLNB IRS4 UNCX PCLO KHDRBS2 NUCB1 CCDC150 NEB OGDH DCTN1 AAR2 SEC61A2 GCLC N4BP2 ULK1 ARHGEF2 PPIP5K2 SEC61A1 PLXNA2

4.17e-0514421611935575683
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNB BMS1 MCC MPDZ PTPN23 MCM4 IDE NCKAP5L AAR2 ITPR3 FBXO22 OSBPL3 AGL ADGRL2 SEC61A1

5.09e-059741611528675297
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 IRS4 DSC2 MPDZ NCKAP5L DNAH7 ALMS1 SAMD11 OSBPL3 N4BP2 DOCK7 OSBPL10 ARHGEF2 PPIP5K2

5.14e-058611611436931259
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

PRAMEF15 WDR81 PRAMEF4 ABHD4 MAGI2 CDH6 PRAMEF11 ALPP ALPG

5.28e-05363161914691545
Pubmed

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.

CDX2 PRAMEF15 PRAMEF4 PRAMEF11

6.20e-0546161417287250
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RALGAPA1 DSC2 DSC3 PEG10 NUCB1 BMS1 EXOC3 MPDZ NCKAP5L OGDH DCTN1 AAR2 ITPR3 SEC61A2 SUPT6H SCD N4BP2 ADGRL2 SEC61A1

6.28e-0514871611933957083
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF15 PRAMEF4 PRAMEF11

6.31e-0517161323565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF15 PRAMEF4 PRAMEF11

6.31e-0517161337781892
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL2 ADGRL3

6.37e-053161210994649
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

6.37e-053161218403125
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

6.37e-053161211171121
Pubmed

NRF1 mitigates motor dysfunction and dopamine neuron degeneration in mice with Parkinson's disease by promoting GLRX m6 A methylation through upregulation of METTL3 transcription.

METTL3 NRF1

6.37e-053161237735974
Pubmed

Prenatal development of transient receptor potential vanilloid 1-expressing primary sensory projections to sacral autonomic preganglionic neurons.

TRPV1 NOS1

6.37e-053161216973277
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR3

6.37e-05316127876312
Pubmed

The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.

USP9X PEG10

6.37e-053161230951545
Pubmed

Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion.

KLF15 SCD

6.37e-053161221862590
Pubmed

Regulation of differential proton-coupled folate transporter gene expression in human tumors: transactivation by KLF15 with NRF-1 and the role of Sp1.

NRF1 KLF15

6.37e-053161230914440
Pubmed

Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.

KHDRBS2 LRRK2

6.37e-053161224652679
Pubmed

Characterization of the interaction of amphipathic cytochrome b5 with stearyl coenzyme A desaturase and NADPH:cytochrome P-450 reductase.

CYP1A1 SCD

6.37e-05316126102994
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR3

6.37e-053161222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR3

6.37e-053161210788707
Pubmed

Organic pyrophosphates as substrates for human alkaline phosphatases.

ALPP ALPG

6.37e-053161216742561
Pubmed

The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.

KLF15 PER3

6.37e-053161229186676
Pubmed

Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels.

TRPV1 PIEZO2

6.37e-053161234825354
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR3

6.37e-05316127621815
Pubmed

SIRT1 accelerates the progression of activity-based anorexia.

NRF1 GRIN2A

6.37e-053161232499508
Pubmed

The influence of desmocollin 1-3 expression on prognosis after curative resection of colorectal liver metastases.

DSC2 DSC3

6.37e-053161223975055
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR3

6.37e-053161210473538
Pubmed

Compositionally different desmosomes in the various compartments of the human hair follicle.

DSC2 DSC3

6.37e-05316129810708
Pubmed

Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.

DSC2 DSC3

6.37e-05316129389456
Pubmed

Assignment of the human genes for desmocollin 3 (DSC3) and desmocollin 4 (DSC4) to chromosome 18q12.

DSC2 DSC3

6.37e-05316127774948
Pubmed

A novel form of capsaicin-modified amygdala LTD mediated by TRPM1.

TRPV1 NOS1

6.37e-053161227633915
Cytoband1p36.21

PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF11

2.97e-066316151p36.21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PITHD1 PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 DFFB PER3 SAMD11 PRDM16 PRAMEF27 PRAMEF11 EPHA8

5.76e-0668116112chr1p36
Cytoband14q11.1

METTL3 RNASE12

5.40e-0410161214q11.1
Cytoband5q21

MCC CPEB4

7.88e-041216125q21
Cytoband7q21

PEG10 MAGI2

9.29e-041316127q21
GeneFamilyPRAME family

PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

3.05e-09241006686
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

9.05e-0531002287
GeneFamilyAlkaline phosphatases

ALPP ALPG

1.80e-04410021072
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL2 ADGRL3

1.80e-0441002918
GeneFamilyDesmosomal cadherins

DSC2 DSC3

6.25e-04710021188
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 WDFY4

1.06e-03910021230
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL3 OSBPL10

1.93e-03121002670
GeneFamilyCD molecules|Type II classical cadherins

CDH6 CDH9

2.27e-031310021186
GeneFamilyKallikreins

KLK6 KLK1

3.46e-03161002616
GeneFamilyAminopeptidases|CD molecules

ANPEP DNPEP

3.90e-03171002104
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

DSC2 NEBL ANPEP PEG10 FAT3 MCC MPDZ MCM4 SCRN1 DNAH7 MAGI2 HEY1 SCD NYNRIN SCN2A WDR35 ADGRL2 CDH6 PLXNA2 ADGRL3 DSE MBNL3

1.25e-0782715322gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_100

DSC2 ANPEP MAGI2 ADGRL3 MBNL3

3.67e-06331535gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_100
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

DSC2 ANPEP PEG10 FAT3 MCC MPDZ RNASE12 MAGI2 NYNRIN SCN2A ZSCAN18 WDR35 PPIP5K2 ADGRL2 CDH6 PLXNA2 ADGRL3 MBNL3 CDON

3.77e-0678315319gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

DSC2 ANPEP PEG10 FAT3 MCC DNAH7 MAGI2 NYNRIN ZSCAN18 KLHL8 PPIP5K2 NOS1 CDH6 PLXNA2 ADGRL3 DSE MBNL3 CDON

1.82e-0579715318gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_100

DSC2 ANPEP MAGI2 CDH6 ADGRL3 MBNL3

2.46e-05801536gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_100
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

DSC2 ANPEP DNAH7 MAGI2 KLHL8 PPIP5K2 NOS1 ADGRL3 MBNL3 CDON

2.72e-0527015310gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

DSC2 PEG10 FAT3 MCC MPDZ DNAH7 MAGI2 NYNRIN SCN2A ZSCAN18 WDR35 ADGRL2 CDH6 PLXNA2 ADGRL3 MBNL3 CDON

1.06e-0483115317gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

DSC2 ANPEP PEG10 MAGI2 NYNRIN SCN2A ADGRL2 CDH6 ADGRL3 MBNL3 CDON

1.21e-0438815311gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

GABRB2 ABCC4 UNCX RNASE12 SCRN1 TMEM52B SNCAIP CCDC198 HEY1 PRDM16 CDH6

1.51e-0439815311gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500

NEBL UNCX USP9X CYB561D2 TTYH2 SCRN1 TMEM52B CCDC198 HEY1 PRDM16 CDH6

1.80e-0440615311gudmap_developingKidney_e15.5_S-shaped body_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

DSC2 ANPEP PEG10 FAT3 MCC MAGI2 SNCAIP NYNRIN SCN2A PPIP5K2 ADGRL2 CDH6 PLXNA2 ADGRL3 MBNL3 CDON

2.12e-0479715316gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500

DSC2 ANPEP DNAH7 ADGRL2 ADGRL3 MBNL3 CDON

2.20e-041681537gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

DSC2 DNAH7 MAGI2 ADGRL2 PLXNA2 ADGRL3 MBNL3 CDON

2.26e-042241538gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

DSC2 NEBL FAT3 MCC SCRN1 NYNRIN SCN2A ADGRL2 CDH6 ADGRL3 MBNL3

2.31e-0441815311gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasMyeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3

ANPEP LRRK2 WDFY4 GCSAM ALMS1 LPCAT2 FCGR2B GCLC OSBPL3 DOCK7 CDON

2.66e-0442515311GSM538255_500
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_k-means-cluster#3_top-relative-expression-ranked_1000

GINM1 MCC LRCH1 SNCAIP CPEB4

2.83e-04801535gudmap_kidney_adult_RenMedVasc_Tie2_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

PEG10 NYNRIN SCN2A ADGRL3 MBNL3 CDON

2.94e-041251536gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

PIK3AP1 NRG1 ABCC4 NEBL ANPEP KHDRBS2 LRRK2 RHEX CCDC198 SLC28A1 OSBPL10 CDH6 CDH9

1.64e-131841611351ed1ebfdef45149541917c66cbacad87072e51f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 ABCC4 KHDRBS2 LRRK2 SULT1C4 RHEX SLC28A1 OSBPL10 CDH6 CDH9

1.62e-0918616110f28d72b47624b69a580b4429e2be560a26898591
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 ABCC4 NEBL FAT3 LRRK2 DNAH7 MAGI2 RHEX CCDC198 ADGRL3

1.89e-0918916110904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 ABCC4 KHDRBS2 LRRK2 RHEX SLC28A1 CDH6 CDH9

1.94e-08179161958ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ANPEP PCLO RHEX CCDC198 SLC28A1 OSBPL10 CDH6 CDH9

2.03e-081801619358923e4228035a3e90e2957392089219e90dcd7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NEBL UNCX LRRK2 GRIN2A MAGI2 RHEX CCDC198 OSBPL10

2.24e-081821619eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

NRG1 ABCC4 ANPEP KHDRBS2 RHEX GCLC SLC28A1 OSBPL10 CDH6

2.83e-081871619d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 ABCC4 KHDRBS2 RHEX CCDC198 SLC28A1 OSBPL10 CDH6 CDH9

3.10e-08189161928b502611829e4a24caff2562545c7db97686099
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 NEBL FAT3 LRRK2 DNAH7 RHEX CCDC198 OSBPL10 ADGRL3

3.39e-081911619d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DSC2 NEBL FAT3 CNTNAP3 F5 RYR3 BSND NOS1 CDON

4.06e-081951619d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DSC2 NEBL FAT3 CNTNAP3 F5 RYR3 BSND NOS1 CDON

4.06e-08195161919853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ANPEP PCLO RHEX CCDC198 SLC28A1 CDH6 CDH9

2.87e-07178161823a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 NEBL LRRK2 MAGI2 RHEX CCDC198 OSBPL10 ADGRL3

2.87e-071781618c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ANPEP RHEX CCDC198 SLC28A1 OSBPL10 CDH6 CDH9

3.13e-071801618864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NEBL LRRK2 GRIN2A MAGI2 RHEX CCDC198 OSBPL10

3.26e-0718116189d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL FAT3 LRRK2 MAGI2 RHEX CCDC198 LPCAT2 ADGRL3

3.26e-071811618071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 DNAH7 RHEX CCDC198 SLC28A1 OSBPL10 CDH6 CDH9

3.55e-0718316186878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL FAT3 LRRK2 MAGI2 RHEX CCDC198 OSBPL10 ADGRL3

3.55e-07183161892fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 FAT3 PCLO NEB RYR3 PIEZO2 SCN2A ADGRL3

3.70e-0718416182cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 FAT3 PCLO NEB RYR3 PIEZO2 SCN2A ADGRL3

3.70e-071841618ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 FAT3 PCLO NEB RYR3 PIEZO2 SCN2A ADGRL3

3.70e-0718416182b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 NEBL FAT3 LRRK2 DNAH7 MAGI2 RHEX ADGRL3

3.70e-071841618da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ANPEP PCLO RHEX CCDC198 SLC28A1 CDH6 CDH9

3.85e-0718516181bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 LRRK2 RHEX CCDC198 OSBPL10 CDH6 ADGRL3

4.02e-0718616185c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

FLNB ABCC4 NEBL SLC45A4 SNCAIP HEY1 PRDM16 PLXNA2

4.18e-07187161840ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ANPEP LRRK2 RHEX CCDC198 SLC28A1 OSBPL10 CDH6

4.18e-0718716189d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 PCLO RHEX CCDC198 SCN2A SLC28A1 CDH6 CDH9

4.18e-071871618d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NEBL LRRK2 MAGI2 RHEX CCDC198 OSBPL3 OSBPL10

4.18e-071871618c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LRRK2 DNAH7 MAGI2 CCDC198 OSBPL10 CDH6 CDH9

4.36e-071881618af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 ABCC4 LRRK2 SULT1C4 RHEX CCDC198 OSBPL10 CDH6

4.53e-0718916183b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 ABCC4 NEBL LRRK2 DNAH7 RHEX CDH6

4.53e-071891618bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 ANPEP KHDRBS2 RHEX SLC28A1 OSBPL10 CDH6 CDH9

4.72e-071901618989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 ABCC4 LRRK2 SULT1C4 RHEX CCDC198 OSBPL10 CDH6

4.91e-0719116181cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DDAH2 SCRN1 WDFY4 RHEX FCGR2B OSBPL10 KLK1 VEGFB

5.11e-071921618e33579a20ca86dcaf02c97273681ba5eee7561b8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL FAT3 SLC45A4 RHEX CCDC198 OSBPL3 SCN2A PRDM16

5.97e-071961618c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ENTPD7 NRG1 COL7A1 DSC3 MCC CROT GCLC ADGRL2

6.20e-0719716181e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RALGAPA1 MCHR1 NEBL FAT3 L1TD1 PIEZO2 KLHL8

8.74e-0714216177b6678a73d04feac12bbc909f2df478215511de0
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RALGAPA1 MCHR1 NEBL FAT3 L1TD1 PIEZO2 KLHL8

8.74e-071421617347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 NEBL LRRK2 RHEX CCDC198 CDH6

1.44e-061531617d6526d17826470534b766df144c74e73eb83fdad
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

HDAC9 DSC3 TTYH2 WDFY4 GCSAM RHEX NOS1

2.02e-061611617cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 LRRK2 GRIN2A SLC45A4 MAGI2 CPEB4

2.29e-061641617382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

HDAC9 ANPEP PDGFB WDFY4 GCSAM TBX19 RHEX

2.48e-0616616170590e404f45afce90e20f93f90a3def83949c66b
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 DNAH7 MAGI2 RHEX CCDC198 OSBPL10 CDH6

2.69e-061681617a086c306be430adf0632ba53e98cd8014d2de330
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LRRK2 ABHD4 TBC1D16 SCD CPEB4 KLHL8

3.14e-061721617356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LRRK2 ABHD4 TBC1D16 SCD CPEB4 KLHL8

3.14e-06172161746fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LRRK2 ABHD4 TBC1D16 SCD CPEB4 KLHL8

3.14e-061721617438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 NEBL LRRK2 DNAH7 CCDC198 OSBPL10

3.52e-061751617284fdc7a9d303636a637041846850d19d114861a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL FAT3 LRRK2 MAGI2 RHEX CCDC198 ADGRL3

3.65e-061761617327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 DNAH7 MAGI2 RHEX CCDC198 OSBPL10 CDH6

3.94e-061781617544379f5a6145429762258d426b876bb36c112f5
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

MOK LRRK2 TRMT11 DCTN1 ITPR3 SEC61A2 GCLC

4.08e-06179161768511e87b12b8253de7771e5ccfc5869248b8450
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NEBL LRRK2 DNAH7 TBC1D16 CCDC198 ADGRL3

4.39e-0618116176a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 FAT3 LRRK2 MAGI2 RHEX CCDC198

4.39e-0618116176956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 PCLO RHEX CCDC198 SLC28A1 CDH6 CDH9

4.39e-0618116176980ea624151da32b7f537f263e40fcb87a02e81
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 DSC2 TMEM52B BSND TBC1D16 GCLC KLK1

4.56e-0618216172ef6889321fd0104d277518d130e19143b3af41c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NRG1 NEBL LRRK2 MAGI2 RHEX CCDC198

4.56e-0618216175e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 FLNB DSC2 TMEM52B BSND GCLC KLK1

4.56e-06182161775608f80fd570da499891dc02f8649d5428b896c
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO RHEX CCDC198 SCN2A SLC28A1 CDH6 CDH9

4.56e-0618216179d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL FAT3 LRRK2 MAGI2 RHEX CCDC198 ADGRL3

4.72e-061831617738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 DSC2 ANPEP RETSAT F5 GCLC AGL

4.72e-061831617d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 TMEM52B OSBPL3 SCN2A CPEB4 ADGRL2 PRDM16

4.72e-0618316172e831a4d99c6f983793df71c0994124c943c6da9
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 HDAC9 ANPEP LRRK2 WDFY4 GCSAM RHEX

4.90e-061841617315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 UNCX WDFY4 GCSAM NWD2 SCN2A MDGA1

5.07e-061851617c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 NEBL LRRK2 SLC45A4 TBC1D16 RHEX ADGRL3

5.26e-0618616173dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 FLNB DSC2 DSC3 F5 NOS1 ADGRL3

5.26e-06186161792092f11ecce22c14f244e42c499af0822977e6f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 KHDRBS2 SULT1C4 RHEX CCDC198 OSBPL10 CDH6

5.26e-061861617b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LRRK2 DNAH7 MAGI2 OSBPL10 CDH6 CDH9

5.44e-061871617c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 TMEM52B OSBPL3 SCN2A CPEB4 PRDM16 NOS1

5.64e-061881617bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 TMEM52B OSBPL3 SCN2A CPEB4 PRDM16 NOS1

5.64e-061881617eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 TMEM52B OSBPL3 SCN2A CPEB4 ADGRL2 PRDM16

5.84e-061891617975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 TMEM52B OSBPL3 SCN2A CPEB4 ADGRL2 PRDM16

5.84e-0618916177eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

NRG1 ABCC4 ANPEP RHEX SLC28A1 OSBPL10 CDH6

5.84e-0618916170be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

NRG1 COL7A1 DSC3 KHDRBS2 MCC LRCH1 LPCAT2

6.04e-0619016174f15842b424eefadbfe451875e517cf70e29607f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DSC2 NEBL UNCX LRRK2 CCDC198 LPCAT2

6.04e-061901617b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB F5 SLC45A4 SNCAIP HEY1 SAMD11 PRDM16

6.04e-061901617aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

GABRB2 ZCCHC12 PEG10 FAT3 PCLO SCN2A ADGRL3

6.04e-0619016176e92c78799f34b31d098854503c796edb0dc7f80
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DSC2 NEBL UNCX FAT3 LRRK2 LPCAT2

6.04e-061901617a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ANPEP RHEX SLC28A1 OSBPL10 CDH6 CDH9

6.25e-0619116173c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ANPEP RHEX SLC28A1 OSBPL10 CDH6 CDH9

6.25e-0619116171c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFB KHDRBS2 MCC GRIN2A SULT1C4 ADGRL2 ADGRL3

6.25e-061911617f229abf69a1217194f74b0502486907e07dba989
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

ABCC4 MCC SLC45A4 LPCAT2 HEY1 PRDM16 NOS1

6.47e-0619216177e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellHealthy_donor-B_intermediate|World / disease group, cell group and cell class (v2)

HDAC9 WDFY4 RHEX FCGR2B OSBPL10 KLK1 VEGFB

6.47e-061921617f77007b284e11f8654ad599eef929df7c6c4ebf0
ToppCellwk_20-22-Hematologic-Myeloid-DC1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HDAC9 ANPEP LRRK2 WDFY4 GCSAM RHEX DSE

6.69e-061931617a260d943e9db966e4ce7d642313fd11354c2d2ba
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SCRN1 WDFY4 FCGR2B OSBPL10 BCL10 KLK1 VEGFB

6.69e-0619316179f798a1bbd9f076c3122d02ed28418c18bb7a369
ToppCellsevere-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HDAC9 PEG10 KHDRBS2 WDFY4 RHEX FCGR2B OSBPL10

7.16e-06195161773e39005a597e13aea571ae6ae5824d1c7448b71
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 NEBL FAT3 KHDRBS2 LRRK2 GRIN2A SCN2A

7.16e-061951617787e95fb59c40bba784544b662fac37606ae1427
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 PCSK2 NRG1 FAT3 KHDRBS2 GRIN2A SCN2A

7.16e-0619516172e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 PCSK2 PCLO KHDRBS2 GRIN2A SCN2A ADGRL2

7.40e-061961617676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL PCLO LRRK2 DNAH7 RHEX CCDC198 CPEB4

7.40e-0619616176ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL PCLO DNAH7 CCDC198 OSBPL3 CPEB4 PRDM16

7.40e-061961617eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 KHDRBS2 NEB WDFY4 FCGR2B OSBPL10 KLK1

7.40e-061961617de43dd0697e1daf4d50800957cf0b27b54a7a333
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LRRK2 DNAH7 SLC45A4 RHEX CCDC198 SCN2A

7.65e-0619716177e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellmyeloid-Monocyte|myeloid / Lineage, cell class and subclass

NRG1 DSC2 ANPEP LRRK2 F5 CFD ULK1

7.65e-0619716176acf059cee6ba6bdeacc089b090d72336790972a
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

DSC2 LRRK2 TTYH2 NEB RYR1 PIEZO2 NOS1

7.65e-06197161715b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

DSC2 LRRK2 TTYH2 NEB RYR1 PIEZO2 NOS1

7.65e-061971617a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

COL7A1 DSC2 MCC CROT GCLC NYNRIN CDH6

7.91e-0619816174235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 PCSK2 PCLO KHDRBS2 GRIN2A SCN2A ADGRL2

7.91e-0619816170ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NRG1 COL7A1 ABCC4 DSC3 KHDRBS2 CROT GCLC

7.91e-0619816175374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NRG1 COL7A1 ABCC4 DSC3 KHDRBS2 CROT GCLC

8.17e-06199161794a7867e800df352731796de8c24cba133c29622
ToppCellsevere-B_memory|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KHDRBS2 SCRN1 WDFY4 FCGR2B OSBPL10 KLK1 VEGFB

8.17e-0619916176d3436dd65d525aaa23ec02672005380f21c4d0f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB2 PCSK2 ZCCHC12 KHDRBS2 GRIN2A SCN2A CDH9

8.45e-0620016172f481e2fd248c02a5aa2e0248c16808df142fed2
Drug8-amino-cADPR

RYR1 RYR3 ITPR3 DFFB

7.09e-07111584CID003081323
Drug2,4-dichlorophenoxyacetic acid

MOK DDAH2 CRAT GCLC SCN2A MLST8 ADGRL2 NOS1

4.00e-061321588CID000001486
Drughomoarginine hydrochloride

ANPEP DCTN1 GCLC NOS1 ALPP ALPG

6.54e-06661586CID000003625
DrugCalcium

CYP1A1 TRPV1 PDGFB OGDH RYR1 RYR3 ITPR3 CFD GCLC ADGRL2 SEC61A1 KLK1 NOS1 ALPP

9.24e-0649315814ctd:D002118
Drugraloxifene hydrochloride; Down 200; 0.1uM; HL60; HG-U133A

RALGAPA1 DSC3 KLF15 CINP ITPR3 SUGP2 NPRL3 CDH6 MBNL3

1.04e-051981589388_DN
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR3 ITPR3

1.12e-0571583CID009547999
Drugpivaloylcarnitine

CRAT CROT PLXNA2

1.12e-0571583CID000126894
DrugBr2BAPTA

RYR1 RYR3 ITPR3

1.12e-0571583CID003081001
DrugHippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A

NEBL PDGFB MCC SGSM3 CPLANE1 ADGRL2 CDH6 CDON VEGFB

1.13e-0520015893682_DN
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A

RALGAPA1 DSC2 NEBL PDGFB DNAH7 KBTBD4 PER3 ALMS1 SGSM3

1.13e-0520015895750_DN
DrugT0702

TRPV1 RYR1 RYR3 ITPR3

2.52e-05251584CID000005908
DrugPD138142-15

CYP1A1 CRAT CFD

2.67e-0591583CID003025787
Drugvinyl sulfone

NRF1 ACR JAK1 GCLC SCN2A

3.02e-05521585CID000006496
DrugAsp-Lys

CDX2 ANPEP IDE DNPEP

3.46e-05271584CID000165361
DrugMUGB

ANPEP ACR CFD

3.80e-05101583CID000134454
DrugPCB 95

CYP1A1 RYR1 RYR3

3.80e-05101583CID000038012
Drugcaged InsP3

RYR1 RYR3 ITPR3 DFFB

4.63e-05291584CID000122248
DrugBAPNA

ACR RYR1 RYR3 CFD KLK1

4.73e-05571585CID000013494
Drug(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium

CRAT CROT

4.79e-0521582DB02648
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

4.79e-0521582ctd:C005147
DrugR 478

RYR1 RYR3 ITPR3

5.19e-05111583CID000084223
DrugCalycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A

DSC2 NRF1 CRAT RYR1 TBX19 HEY1 CDON VEGFB

6.28e-0519315882764_UP
Drugborate

HDAC9 TRPV1 RYR1 RYR3 ITPR3 PACS2

6.32e-05981586CID000007628
Drug17-AAG; Down 200; 1uM; MCF7; HG-U133A

FLNB MCHR1 NEBL KLF15 GRIN2A KBTBD4 ALMS1 NPRL3

6.51e-051941588428_DN
DrugIopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A

ABCC4 DSC2 PDGFB MCC TRMT11 MCM4 MANEA PER3

6.51e-0519415887189_UP
Drug5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA

CYP1A1 NRG1 NEBL CRAT RYR1 TBX19 SGSM3 CDON

6.51e-051941588828_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A

NUCB1 ABHD4 SEC61A2 SUGP2 SUPT6H NPRL3 SGSM3 CDH6

6.51e-0519415884291_DN
Drug2-aminoethoxydiphenyl borate

CYP1A1 TRPV1 PDGFB ITPR3 NOS1

6.57e-05611585ctd:C109986
DrugCelecoxib

GABRB2 RALGAPA1 NRG1 ABCC4 GRIN2A ADAR SLC45A4 ABHD4 JAK1 PNCK EPHA8

6.65e-0537615811ctd:D000068579
DrugCefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A

ENTPD7 COL7A1 TRPV1 NEBL MPDZ CPLANE1 NOS1 PLXNA2

6.75e-0519515886159_UP
DrugMethylatropine nitrate [52-88-0]; Up 200; 11uM; HL60; HT_HG-U133A

MOK IRS4 PDGFB F5 ITPR3 CCDC198 MBNL3 CDON

6.99e-0519615883116_UP
DrugChlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A

RALGAPA1 NEBL DSC3 PCLO BMS1 CFD ALMS1 SGSM3

6.99e-0519615886692_DN
DrugLycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

COL7A1 NRF1 PEG10 F5 NYNRIN KLK1 NOS1 CDON

7.51e-0519815883891_UP
DrugMegestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A

GABRB2 NEBL NRF1 PCLO FAN1 PER3 NPRL3 SGSM3

7.51e-0519815885013_DN
DrugRiboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A

CYP1A1 COL7A1 PDGFB PEG10 ITPR3 MAGI2 TBX19 HEY1

7.51e-0519815882760_UP
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

IRS4 NEBL PEG10 SEC61A2 CROT FBXO22 PER3 CDH6

7.51e-0519815881544_UP
DrugPyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A

MCM4 LRCH1 DFFB ALMS1 SUGP2 SUPT6H NPRL3 DNPEP

7.51e-0519815883482_UP
DrugGriseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A

NEBL NRF1 MANEA CINP TBX19 SEC61A2 OSBPL3 ARHGEF2

7.51e-0519815887363_DN
Drugbenzamidine

KLK6 ACR WDR81 IDE F5 CFD KLK1

7.66e-051471587CID000002332
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HG-U133A

GABRB2 RALGAPA1 GIN1 BMS1 CROT SUPT6H AGL PPIP5K2

7.78e-051991588426_UP
DrugZalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A

CYP1A1 NEBL PDGFB NUCB1 NYNRIN NPRL3 NOS1 CDH6

7.78e-0519915884799_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A

TRPV1 NUCB1 NEB F5 TBX19 PACS2 ADGRL3 VEGFB

7.78e-0519915882402_DN
DrugPalmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A

COL7A1 METTL3 DSC2 NEBL CINP SEC61A2 ALMS1 CDON

8.05e-0520015886612_DN
DrugBAEE

ACR F5 CFD KLK1 NOS1

8.28e-05641585CID000123880
DrugC13932

TRPV1 GRIN2A OGDH RYR1 RYR3 ITPR3 DFFB NPRL3

9.89e-052061588CID000168297
DrugNP-EGTA

GRIN2A RYR1 RYR3

1.13e-04141583CID000183793
Drugsodium glycocholate

ABCC4 NUCB1 EXOC3 SLC28A1 ALPP

1.19e-04691585CID000000755
Drugmag-fura-2

RYR1 RYR3 ITPR3 DFFB

1.23e-04371584CID000123839
DrugAC1L98DX

RYR1 RYR3 ITPR3 DFFB

1.37e-04381584CID000439957
DrugGvapspat amide

RYR1 RYR3 ITPR3

1.40e-04151583CID000125015
Drugcis-diammineplatinum(II

RYR1 RYR3

1.43e-0431582CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR3

1.43e-0431582CID002750949
Drug8N3-cADPR

RYR1 RYR3

1.43e-0431582CID000127713
Drugaminodantrolene

RYR1 RYR3

1.43e-0431582CID009570289
Drug2-hydroxycarbazole

RYR1 RYR3

1.43e-0431582CID000093551
Drugiodipamide ethyl ester

IDE CFD

1.43e-0431582CID000127535
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

1.43e-0431582CID000080262
Drugflubendiamide

RYR1 RYR3

1.43e-0431582CID011193251
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR3

1.43e-0431582CID005748312
Drug3-keto-4-pentenoyl-CoA

OGDH CRAT

1.43e-0431582CID000157435
Drugphenytoin

COL7A1 PDGFB RYR1 RYR3 ITPR3 SCN2A NOS1 VEGFB

1.51e-042191588CID000001775
DrugNAADP

RYR1 RYR3 ITPR3 DFFB

1.52e-04391584CID000123952
Diseasemyocardial infarction (is_implicated_in)

PCSK2 NRG1 F5 GCLC KLK1 VEGFB

1.38e-05991546DOID:5844 (is_implicated_in)
DiseaseACUTE ALCOHOL WITHDRAWAL

ANPEP MPDZ

2.71e-0521542C0149821
DiseaseHydrocephalus

WDR81 MPDZ

8.09e-0531542cv:C0020255
DiseaseCongenital hydrocephalus

WDR81 MPDZ

8.09e-0531542cv:C0020256
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

8.09e-0531542DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

8.09e-0531542DOID:8545 (implicated_via_orthology)
Diseasesleep duration, low density lipoprotein cholesterol measurement

OGDH BSND MAGI2 GCLC DOCK7

1.18e-04911545EFO_0004611, EFO_0005271
DiseaseDepressive disorder

HDAC9 NRG1 MCHR1 PCLO GRIN2A TBX19 PER3 NOS1

1.46e-042891548C0011581
Diseaseperipheral arterial disease

HDAC9 NEBL F5 OSBPL10

1.84e-04541544EFO_0004265
Diseasechronic kidney disease

PCSK2 NRG1 UNCX GRIN2A AGL ADGRL3 CDON

2.45e-042351547EFO_0003884
Diseasearrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)

DSC2 DSC3

2.68e-0451542DOID:0050431 (implicated_via_orthology)
Diseaseclubfoot (is_implicated_in)

CYP1A1 FLNB

2.68e-0451542DOID:11836 (is_implicated_in)
Diseasedesmocollin-2 measurement

DSC2 DSC3

2.68e-0451542EFO_0021936
DiseaseIschemic stroke

HDAC9 NRG1 MPDZ LRCH1 F5 LPCAT2 NYNRIN ADGRL3

3.16e-043241548HP_0002140
Diseasecystic fibrosis (is_implicated_in)

CYP1A1 GCLC NOS1

3.72e-04271543DOID:1485 (is_implicated_in)
DiseaseMental Depression

HDAC9 NRG1 MCHR1 PCLO GRIN2A TBX19 PER3

3.91e-042541547C0011570
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB RYR1

4.00e-0461542C1854678
Diseaseportal hypertension (is_marker_for)

F5 CPEB4

4.00e-0461542DOID:10762 (is_marker_for)
Diseasehydrocephalus (is_implicated_in)

WDR81 MPDZ

4.00e-0461542DOID:10908 (is_implicated_in)
DiseaseMammary Carcinoma, Human

CYP1A1 NRG1 COL7A1 DSC3 TRMT11 ADAR PER3 HEY1 SLC28A1 VEGFB

4.57e-0452515410C4704874
DiseaseMammary Neoplasms, Human

CYP1A1 NRG1 COL7A1 DSC3 TRMT11 ADAR PER3 HEY1 SLC28A1 VEGFB

4.57e-0452515410C1257931
DiseaseMammary Neoplasms

CYP1A1 NRG1 COL7A1 DSC3 TRMT11 ADAR PER3 HEY1 SLC28A1 VEGFB

4.70e-0452715410C1458155
Diseasecaudate nucleus volume

MOK FAT3 PRDM16

5.10e-04301543EFO_0004830
DiseaseAlcoholic Intoxication, Chronic

GABRB2 MPDZ GRIN2A TBX19 PER3 CDH9 EPHA8

5.39e-042681547C0001973
DiseaseBreast Carcinoma

CYP1A1 NRG1 COL7A1 DSC3 TRMT11 ADAR PER3 HEY1 SLC28A1 VEGFB

5.52e-0453815410C0678222
DiseaseMorphine Abuse

GRIN2A NOS1

5.59e-0471542C0600272
DiseaseMorphine Dependence

GRIN2A NOS1

5.59e-0471542C0026552
Diseaseinternet addiction disorder

NRG1 FLNB PNCK

6.78e-04331543EFO_0803368
DiseaseParkinson's disease (is_implicated_in)

CYP1A1 KLK6 LRRK2 NOS1

6.84e-04761544DOID:14330 (is_implicated_in)
DiseaseE3 ubiquitin-protein ligase RNF13 measurement

NRG1 F5

7.42e-0481542EFO_0801556
Diseaseallantoin measurement

MAGI2 HEY1

7.42e-0481542EFO_0010456
Diseasepulmonary hypertension (biomarker_via_orthology)

CYP1A1 PDGFB RYR1 RYR3

8.29e-04801544DOID:6432 (biomarker_via_orthology)
DiseaseBipolar Disorder

GABRB2 NRG1 MCHR1 PCLO GRIN2A MAGI2 PER3 SCN2A MDGA1

9.39e-044771549C0005586
Diseasethiamine measurement

NRG1 N4BP2

1.18e-03101542EFO_0010540
Diseasetheophylline measurement

CYP1A1 LRRK2

1.18e-03101542EFO_0021180
DiseaseChronic Kidney Diseases

FAN1 SEC61A1

1.18e-03101542C1561643
Diseaseend stage renal disease (is_implicated_in)

CYP1A1 F5 KLK1

1.28e-03411543DOID:783 (is_implicated_in)
Diseasebitter beverage consumption measurement

CYP1A1 MAGI2 N4BP2

1.38e-03421543EFO_0010089
Diseasebeta-nerve growth factor measurement

KHDRBS2 F5 TBX19

1.38e-03421543EFO_0008035
Diseaseglycerophosphorylcholine measurement

JAK1 EPHA8

1.44e-03111542EFO_0020018
Diseasebronchopulmonary dysplasia

DSC2 DSC3 MAGI2

1.68e-03451543MONDO_0019091
Diseasehydroxy-leucine measurement

NRG1 ALMS1 ADGRL2

1.68e-03451543EFO_0005276
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

NRG1 ITPR3

1.73e-03121542DOID:10595 (is_implicated_in)
DiseaseCongenital myopathy (disorder)

NEB RYR1

1.73e-03121542C0270960
DiseaseNeurobehavioral Manifestations

MAGI2 NOS1

1.73e-03121542C0525041
Diseaseinterleukin 6 receptor subunit alpha measurement

NUP210L ADAR

2.03e-03131542EFO_0008187
Diseasecirrhosis of liver

HDAC9 KLHL8

2.03e-03131542EFO_0001422
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

F5 CFD

2.03e-03131542EFO_0802114
Diseasedepressive symptom measurement, stressful life event measurement

PCLO SNCAIP DSE

2.28e-03501543EFO_0007006, EFO_0007781
DiseaseYu-Zhi constitution type

GABRB2 PIEZO2

2.72e-03151542EFO_0007638
Diseasemean platelet volume

HDAC9 NRF1 NUP210L LRRK2 SULT1C4 LRCH1 SLC45A4 SCD CPEB4 DOCK7 KLHL8 PRDM16 DSE

2.75e-03102015413EFO_0004584
DiseaseAcute Cerebrovascular Accidents

HDAC9 LRCH1 F5

2.85e-03541543C0751956
Diseaseneuroticism measurement, cognitive function measurement

NUP210L PCLO RNASE12 GRIN2A N4BP2 SCN2A OSBPL10 NOS1 CDH9

3.00e-035661549EFO_0007660, EFO_0008354
DiseasePolyposis, Adenomatous Intestinal

MCC F5

3.10e-03161542C2713442
DiseaseFamilial Intestinal Polyposis

MCC F5

3.10e-03161542C2713443
Diseaseserum gamma-glutamyl transferase measurement

ENTPD7 PIK3AP1 NUP210L MCC KLF15 FCGR2B GCLC ULK1 KLHL8 ARHGEF2 ADGRL2 CDH6

3.14e-0391415412EFO_0004532
Diseasediabetic neuropathy (biomarker_via_orthology)

NRG1 LRRK2

3.50e-03171542DOID:9743 (biomarker_via_orthology)
DiseaseAdenomatous Polyposis Coli

MCC F5

3.50e-03171542C0032580
Diseaseserum urea measurement

CYP1A1 UNCX FBXO22 ARHGEF2 ADGRL2

3.66e-031951545EFO_0009795
Diseaseserum metabolite measurement

RALGAPA1 CYP1A1 ABCC4 CRAT SLC45A4 MAGI2 NWD2 ALMS1 DOCK7 SLC28A1 NPRL3 MDGA1

4.10e-0394515412EFO_0005653
DiseaseCerebrovascular accident

HDAC9 LRCH1 F5

4.21e-03621543C0038454
DiseaseMalignant neoplasm of breast

CYP1A1 NRG1 FLNB COL7A1 DSC3 TRMT11 MANEA ADAR PER3 HEY1 N4BP2 SLC28A1 VEGFB

4.25e-03107415413C0006142
Diseaseblood metabolite measurement

CRAT ALMS1

4.37e-03191542EFO_0005664
Diseasedense area measurement, mammographic density measurement

MAGI2 SGSM3

4.37e-03191542EFO_0005941, EFO_0006503

Protein segments in the cluster

PeptideGeneStartEntry
LLDKDVSMYPSSVRH

CDX2

6

Q99626
MTDAGRPHSEAAYTL

CNTNAP3

766

Q9BZ76
GSLYPEMSAHERSLD

DCTN1

686

Q14203
LATEPHVRMVTLYDN

DNPEP

296

Q9ULA0
HYDMETTELPELTST

ACR

406

P10323
PEMYEVHTASRDDRS

ARHGEF2

546

Q92974
AENTITYSLLMHPDA

FCGR2B

286

P31994
TPAEITKHSMDLSYA

AAR2

221

Q9Y312
EDLQSPHRDSLYTSM

ADGRL3

1346

Q9HAR2
KPTRESEYHSSDLRM

ALMS1

446

Q8TCU4
PDSYVRDMEIKGASH

ABHD4

306

Q8TB40
DHLQSPNRDSLYTSM

ADGRL2

1361

O95490
TMPRVSEDVYRSHVA

CRAT

291

P43155
DEYELLMPHRISSHF

GCSAM

146

Q8N6F7
YRVMAVDALASSHPL

ANPEP

441

P15144
DMDSCLSRHSINPYS

DFFB

231

O76075
DAVYESMAHLSTDLL

PIK3AP1

416

Q6ZUJ8
TSHPYILADRMEDLT

BMS1

251

Q14692
DEPDTMHTRLKYSII

DSC2

271

Q02487
VPLHSSMDVTYSPER

NWD2

946

Q9ULI1
LMHLVVESFPSYRDV

C9orf64

181

Q5T6V5
DRSHLPYMEAFILET

CYP1A1

361

P04798
LHELLTYCDSDSSPM

JAK1

1071

P23458
VPMAAHEASSLYSEE

PTPN23

361

Q9H3S7
VEDHSPLMYHISLVD

ITPR3

1356

Q14573
RDSPHSERYVSAMTT

NRG1

416

Q02297
APTHSDYTMTLLDLF

PARP2

391

Q9UGN5
EAEAHARPYMASVQL

CFD

31

P00746
DMASRIIHYTEPINS

MDGA1

731

Q8NFP4
RILPHTVLYMADSET

FBXO22

96

Q8NEZ5
IAYAHSTIMPRLSEE

MCM4

691

P33991
RMDSSGPDYKELDVH

MAGI2

766

Q86UL8
DYSHDLMLLRLTEPA

KLK1

116

P06870
VYSSHSMGARVDLEP

NCKAP5L

751

Q9HCH0
AMADTPEHASDYLRP

ENTPD7

136

Q9NQZ7
VLRHSNYTLPLEESM

GINM1

161

Q9NU53
ETMSHYTDEPRFTIE

HMBOX1

11

Q6NT76
VSITSAHIDPDASYM

MLST8

171

Q9BVC4
IHPDVDEHSVMTYLS

FLNB

221

O75369
PEELYEMLSDHSIRS

PDGFB

26

P01127
SSRLHSYVKAEEDPM

PCLO

4101

Q9Y6V0
SMYSLEELATIASEH

PER3

111

P56645
SILSYLHPEDRSLMV

PER3

306

P56645
DPESSAMLDYELHSD

PLXNA2

206

O75051
MASLSSVERYDPHLD

KLHL8

471

Q9P2G9
LHTYVCLMASPSEEE

NPRL3

406

Q12980
EASRASKPDHIYMDA

GCLC

226

P48506
TYTEHSMLSADEDSP

NRF1

31

Q16656
HVYSLSEPEMAALRD

PEG10

546

Q86TG7
LSHMDVSRYVSPEQK

PRAMEF15

241

P0DUQ1
TADSLYLHTMERPHL

LRCH1

296

Q9Y2L9
PHLRSLDMSSNDIQY

LRRK2

1196

Q5S007
LTEAVHTMLSSPLEY

DSE

71

Q9UL01
YTMDPHENILLSTLE

GABRB2

396

P47870
LLHAMVAYDPDERIA

MOK

261

Q9UQ07
LDLLYDTLDMEHPSD

PACS2

286

Q86VP3
VEMHPAYTEEELRRF

NUCB1

336

Q02818
YSSRDPSVIETHMRQ

MANEA

161

Q5SRI9
EVRSTSHKPDEIYGM

METTL3

506

Q86U44
SISSSPDMYPDEVHL

NOS1

1181

P29475
TAAEYMLSDALLPDR

PANX3

6

Q96QZ0
LEDVHESPSHLYLAM

PNCK

76

Q6P2M8
IPVTDHTYEDCRLMI

LPCAT2

316

Q7L5N7
EDDMYSVLPEDRSQH

ABCC4

41

O15439
MKYEIHRDSTLDPSL

ALPP

296

P05187
GDMKYEIHRDSTLDP

ALPG

291

P10696
SLLRHPEARSSFDEM

OGDH

861

Q02218
TMLELESIHIDPLSY

MCC

586

P23508
VMSYSEDHRSLLAPE

BSND

121

Q8WZ55
AYLRSEIMSLHEASE

CCDC150

326

Q8NCX0
ESEMDPHVRDCIRSY

DOCK7

106

Q96N67
DEPDTMHTRLKYSIL

DSC3

271

Q14574
CSDRAMESTESRHYP

ADAR

976

P55265
AVPSSAELHYMAASV

CPLANE1

2626

Q9H799
KLRASTVMYHPEGES

BCL10

146

O95999
HSEERDTPKMYCSAE

EPHA8

236

P29322
HLAELEPSSLYEVLM

CDON

641

Q4KMG0
MKESVAPTEHLRLYD

DNAH7

481

Q8WXX0
YSLHSDSQPEKVMEA

FAT3

2851

Q8TDW7
RYAHPTDASMIEASD

MBNL3

196

Q9NUK0
TESPKVRDMYATHLA

MAN2B2

426

Q9Y2E5
MAIDRYLATVHPISS

MCHR1

206

Q99705
PGEAYSRMSHALEEI

KHDRBS2

141

Q5VWX1
AYHMLPSPVSEDDSD

KLF15

31

Q9UIH9
MKRAHPEYSSSDSEL

HEY1

1

Q9Y5J3
PVKYSVDRHTDMDRI

CDH6

416

P55285
TAVVTAHRYMLAPDA

COL7A1

1136

Q02388
DRPRTFDMHSLESSL

CPEB4

376

Q17RY0
PHYLESRVEAFLITM

IDE

856

P14735
PRIVRESYAMTSAHE

CCDC168

6566

Q8NDH2
IHEDSMNLLSLYTSP

HDAC9

311

Q9UKV0
VRAMAVLTDHPYASL

DDAH2

196

O95865
LSPHVVSELLDTYMS

EXOC3

371

O60645
SRDMYFDIPLEHRET

CCDC198

76

Q9NVL8
EAVMSTLEHLHVDYP

RNASE12

21

Q5GAN4
LAESGARYTEMPHVI

RYR1

3256

P21817
MLYTLRVDASNTHPD

CDH9

341

Q9ULB4
MALSAETESHIYRAL

CYB561D2

1

O14569
SSLLVYSMEDSSPHV

CROT

271

Q9UKG9
QSMDVLHRTYSAPAI

OSBPL3

241

Q9H4L5
TYMEAESSVELVPLH

NUP210L

941

Q5VU65
MDSHRDAIPDYEALV

NYNRIN

1101

Q9P2P1
TPAMALADSAIRYDA

IRS4

1026

O14654
DLIRYAAATHMLSDI

FAN1

601

Q9Y2M0
ERYVSMPREEAAEHI

RETSAT

421

Q6NUM9
TDPSITHENMDAYLS

RIOK1

386

Q9BRS2
SDYHEERTILPMSRA

USP9X

866

Q93008
VPVSLSYHLSDMFLD

TRMT11

341

Q7Z4G4
DIPMSDSLYRHDSDT

RHEX

76

Q6ZWK4
DTSMVHELNRYIPTA

SEC61A2

406

Q9H9S3
HRSSSPELSEMLEYD

F5

1146

P12259
PELSEMLEYDRSHKS

F5

1151

P12259
MWLADRHSDPELYTA

KBTBD4

151

Q9NVX7
MYEPNRDLLASHSAE

PRDM16

21

Q9HAZ2
RNPYMPETSDSLHEV

GIN1

291

Q9NXP7
LSHMDVSRYVSPEQK

PRAMEF25

241

A6NGN4
VELTPDYSMESHQRD

SGSM3

456

Q96HU1
MTTEVILHYRPCESD

SHLD3

1

Q6ZNX1
PSTSLGELEHYDLDM

SNCAIP

136

Q9Y6H5
MAPEDHYRRLVSALS

SAMD11

186

Q96NU1
LSHMDVSRYVSPEQK

PRAMEF27

241

A3QJZ7
SRDSPLKTLMSHYEE

NFATC2IP

366

Q8NCF5
PSSSYASDHDMIVSI

OR5T2

301

Q8NGG2
LSDEAPHMLVVYSAN

OSBPL10

131

Q9BXB5
KMDAEHPELRSYAQS

SCRN1

196

Q12765
YVESDSRLHLESMLL

CINP

191

Q9BW66
HELALDYPDVDIMRS

SLC45A4

291

Q5BKX6
MYEPSELESSHLTDQ

SUPT6H

271

Q7KZ85
LSHMDVSRYVSPEQK

PRAMEF4

241

O60810
HLLPSTEASSYEMDK

RALGAPA1

1371

Q6GYQ0
LASVDYDPFMHLESL

RALGAPA1

1456

Q6GYQ0
DPVLDLHMSLEELYT

MPDZ

891

O75970
AYSSSETPNRHDMLL

TRPV1

401

Q8NER1
ETSMVHELNRYIPTA

SEC61A1

406

P61619
EDDDSHPSEMRLYKN

PITHD1

96

Q9GZP4
DLAESGARYTEMPHV

RYR3

3116

Q15413
PSMRATYLSVADEHL

TTYH2

511

Q9BSA4
LSHMDVSRYVSPEQK

PRAMEF9

241

P0DUQ2
HLLAESYSAVMELTR

SOGA1

821

O94964
NYSSIPAEIMDHSIS

SULT1C4

246

O75897
THPEESMYKRLGVSA

TBC1D16

386

Q8TBP0
VPRSRAEMYDDVHSD

SUGP2

46

Q8IX01
SSYHVSMDLLEDPTS

SCN2A

686

Q99250
SLDTLPGYEEALHMS

TMEM52B

131

Q4KMG9
ATHYPTDERKLLSMT

PIEZO2

391

Q9H5I5
LISLATDDHTMYAAV

WDFY4

1381

Q6ZS81
LSHMDVSRYVSPEQK

PRAMEF11

241

O60813
MPAHLLQDDISSSYT

SCD

1

O00767
IRPYLADMTLSEVHV

SLC28A1

326

O00337
YPSSQLGEMSLEEHS

VEGFB

106

P49765
SILSDGVYERHMDPL

ZSCAN18

146

Q8TBC5
MEDPKSSDIQLYHSE

PPIP5K2

681

O43314
MYSLLLDFVPTDSHR

TBX19

86

O60806
RERIYHVDDTPSGSM

WDR35

476

Q9P2L0
ADYLHAMRTLSEDTI

ULK1

101

O75385
PFVLSLMSEEHTAVY

WDR81

926

Q562E7
THTEMERSRVAPGEY

ZCCHC12

381

Q6PEW1
ESHYPDVFMREALAL

UNCX

126

A6NJT0
TPLHVAEYMLDAARN

AGL

531

P35573
PDYDAASHDQDIMLL

KLK6

96

Q92876
LSIEEFRDYVLHMPT

L1TD1

841

Q5T7N2
LILETPHMYFSDSES

N4BP2

676

Q86UW6
YLPEEMAHSDISETS

GRIN2A

1051

Q12879
HTYSAELDRPDIKMA

NEBL

171

O76041
RQHPDTLKYSTLMDS

NEB

1961

P20929
YDPAEDNIQSRSLHM

NEB

6511

P20929
EASSISHMPQLIDIY

PCSK2

251

P16519