Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity

MAN1A1 MAN1C1

2.38e-048592GO:0004571
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

MAN1A1 MAN1C1 LYG2 SI

2.44e-04103594GO:0004553
GeneOntologyMolecularFunctionmannosyl-oligosaccharide mannosidase activity

MAN1A1 MAN1C1

3.80e-0410592GO:0015924
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

MAN1A1 MAN1C1 LYG2 SI

8.68e-04144594GO:0016798
GeneOntologyMolecularFunctionalpha-mannosidase activity

MAN1A1 MAN1C1

8.79e-0415592GO:0004559
GeneOntologyMolecularFunctioncarbonate dehydratase activity

CA2 CA5A

1.00e-0316592GO:0004089
GeneOntologyMolecularFunctionmannosidase activity

MAN1A1 MAN1C1

1.00e-0316592GO:0015923
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

ZNF451 MIB1 RNF10 HERC2 RNF43 FBXO30

1.12e-03398596GO:0061659
GeneOntologyBiologicalProcesssiRNA-mediated post-transcriptional gene silencing

AGO1 AGO3

5.14e-054612GO:0140766
GeneOntologyBiologicalProcesssiRNA-mediated gene silencing by mRNA destabilization

AGO1 AGO3

5.14e-054612GO:0090625
GeneOntologyBiologicalProcessregulation of cell differentiation involved in phenotypic switching

SOD2 DNMT1

8.55e-055612GO:1905915
GeneOntologyBiologicalProcessregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

SOD2 DNMT1

8.55e-055612GO:1905930
GeneOntologyBiologicalProcessvascular associated smooth muscle cell differentiation involved in phenotypic switching

SOD2 DNMT1

8.55e-055612GO:1905420
GeneOntologyBiologicalProcesscell differentiation involved in phenotypic switching

SOD2 DNMT1

8.55e-055612GO:0090679
GeneOntologyBiologicalProcessubiquitin-dependent glycoprotein ERAD pathway

MAN1A1 MAN1C1

2.38e-048612GO:0097466
GeneOntologyBiologicalProcessprotein deglycosylation involved in glycoprotein catabolic process

MAN1A1 MAN1C1

2.38e-048612GO:0035977
GeneOntologyBiologicalProcessprotein alpha-1,2-demannosylation

MAN1A1 MAN1C1

2.38e-048612GO:0036508
GeneOntologyBiologicalProcessprotein demannosylation

MAN1A1 MAN1C1

2.38e-048612GO:0036507
GeneOntologyBiologicalProcessmannose trimming involved in glycoprotein ERAD pathway

MAN1A1 MAN1C1

2.38e-048612GO:1904382
GeneOntologyBiologicalProcessRNA secondary structure unwinding

AGO1 AGO3

3.06e-049612GO:0010501
GeneOntologyBiologicalProcessRISC complex assembly

AGO1 AGO3

3.81e-0410612GO:0070922
GeneOntologyBiologicalProcessnegative regulation of Notch signaling pathway

HEY1 HERC2 YTHDF2

3.87e-0448613GO:0045746
GeneOntologyCellularComponentP-body

AGO1 AGO3 TNRC6C YTHDF2

2.25e-04102614GO:0000932
GeneOntologyCellularComponentRISC-loading complex

AGO1 AGO3

3.71e-0410612GO:0070578
GeneOntologyCellularComponentcluster of actin-based cell projections

RALGDS LOXHD1 PAFAH1B1 SI PKHD1L1

4.83e-04223615GO:0098862
DomainZZ

DTNB MIB1 HERC2

2.49e-0518603PF00569
DomainZF_ZZ_2

DTNB MIB1 HERC2

2.49e-0518603PS50135
DomainZF_ZZ_1

DTNB MIB1 HERC2

2.49e-0518603PS01357
DomainZnf_ZZ

DTNB MIB1 HERC2

2.94e-0519603IPR000433
DomainZnF_ZZ

DTNB MIB1 HERC2

2.94e-0519603SM00291
DomainArgonaute_N

AGO1 AGO3

6.06e-054602IPR032474
DomainArgonaute_Mid_dom

AGO1 AGO3

6.06e-054602IPR032473
DomainArgoL2

AGO1 AGO3

6.06e-054602IPR032472
DomainMib_Herc2

MIB1 HERC2

6.06e-054602IPR010606
DomainMIB_HERC2

MIB1 HERC2

6.06e-054602PS51416
DomainMIB_HERC2

MIB1 HERC2

6.06e-054602PF06701
DomainArgoN

AGO1 AGO3

6.06e-054602PF16486
DomainArgoMid

AGO1 AGO3

6.06e-054602PF16487
DomainArgoL2

AGO1 AGO3

6.06e-054602PF16488
DomainDUF1785

AGO1 AGO3

1.01e-045602SM01163
DomainArgoL1

AGO1 AGO3

1.51e-046602PF08699
DomainArgoL1

AGO1 AGO3

1.51e-046602IPR014811
DomainGlyco_hydro_47

MAN1A1 MAN1C1

2.11e-047602PF01532
Domain-

MAN1A1 MAN1C1

2.11e-0476021.50.10.50
DomainPIWI

AGO1 AGO3

2.81e-048602PS50822
DomainPiwi

AGO1 AGO3

2.81e-048602SM00950
DomainPiwi

AGO1 AGO3

2.81e-048602IPR003165
DomainPiwi

AGO1 AGO3

2.81e-048602PF02171
DomainGlyco_hydro_47

MAN1A1 MAN1C1

2.81e-048602IPR001382
DomainPAZ

AGO1 AGO3

3.60e-049602PS50821
DomainPAZ

AGO1 AGO3

3.60e-049602SM00949
DomainPAZ_dom

AGO1 AGO3

3.60e-049602IPR003100
DomainPAZ

AGO1 AGO3

3.60e-049602PF02170
DomainCarbonic_anhydrase_a-class_CS

CA2 CA5A

6.56e-0412602IPR018338
DomainCarbonic_anhydrase_a-class

CA2 CA5A

1.04e-0315602IPR023561
DomainALPHA_CA_1

CA2 CA5A

1.04e-0315602PS00162
DomainALPHA_CA_2

CA2 CA5A

1.34e-0317602PS51144
DomainCarb_anhydrase

CA2 CA5A

1.34e-0317602PF00194
DomainCarb_anhydrase

CA2 CA5A

1.34e-0317602SM01057
Domain-

CA2 CA5A

1.34e-03176023.10.200.10
DomainCarbonic_anhydrase_a

CA2 CA5A

1.34e-0317602IPR001148
DomainMAM

MALRD1 MAMDC4

1.34e-0317602SM00137
DomainMAM

MALRD1 MAMDC4

1.50e-0318602PF00629
DomainMAM_dom

MALRD1 MAMDC4

1.50e-0318602IPR000998
DomainMAM_2

MALRD1 MAMDC4

1.50e-0318602PS50060
DomainRCC1

RCCD1 HERC2

1.86e-0320602PF00415
DomainRCC1_1

RCCD1 HERC2

2.05e-0321602PS00625
DomainRCC1_2

RCCD1 HERC2

2.05e-0321602PS00626
DomainRCC1_3

RCCD1 HERC2

2.05e-0321602PS50012
DomainReg_chr_condens

RCCD1 HERC2

2.25e-0322602IPR000408
Domain-

RCCD1 HERC2

2.25e-03226022.130.10.30
DomainRCC1/BLIP-II

RCCD1 HERC2

2.46e-0323602IPR009091
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO3 TNRC6C

9.17e-077433M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

AGO1 AGO3 TNRC6C

2.19e-069433M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

AGO1 AGO3 TNRC6C

2.19e-069433M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

AGO1 AGO3 TNRC6C

3.13e-0610433M48013
PathwayREACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER

AGO1 AGO3 TNRC6C DNMT1

3.67e-0635434M42525
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

AGO1 AGO3 TNRC6C

7.40e-0613433M46434
PathwayREACTOME_SIGNALING_BY_NOTCH

HDAC11 AGO1 AGO3 HEY1 MIB1 TNRC6C ATP2A1

8.53e-06246437M10189
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

AGO1 AGO3 TNRC6C

1.74e-0517433M27788
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

AGO1 AGO3 TNRC6C

2.48e-0519433M48238
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

HDAC11 AGO1 AGO3 HEY1 MIB1 TNRC6C RNF43 DNMT1

6.82e-05464438M27547
PathwayREACTOME_TGFBR3_EXPRESSION

AGO1 AGO3 TNRC6C

8.21e-0528433M48253
PathwayREACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI

MAN1A1 MAN1C1

9.04e-055432M27954
PathwayBIOCARTA_DICER_PATHWAY

AGO1 AGO3

9.04e-055432M22079
PathwayREACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI

MAN1A1 MAN1C1

9.04e-055432MM15670
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

AGO1 AGO3 TNRC6C

1.23e-0432433M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

AGO1 AGO3 TNRC6C

1.23e-0432433M27900
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO1 AGO3

1.35e-046432MM14818
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO3

1.35e-046432MM15083
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

AGO1 AGO3 TNRC6C

1.48e-0434433M46422
PathwayREACTOME_ONCOGENE_INDUCED_SENESCENCE

AGO1 AGO3 TNRC6C

1.62e-0435433M27190
PathwayREACTOME_SIGNALING_BY_ALK_IN_CANCER

AGO1 AGO3 TNRC6C DNMT1

1.80e-0493434M42521
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

AGO1 AGO3 TNRC6C

1.91e-0437433M29790
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO3

2.52e-048432MM15082
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

AGO1 AGO3 TNRC6C

2.60e-0441433M29748
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO3

3.23e-049432M27340
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

AGO1 AGO3 TNRC6C

3.90e-0447433M29777
PathwayREACTOME_SIGNALING_BY_TGFBR3

AGO1 AGO3 TNRC6C

4.42e-0449433M48250
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

AGO1 AGO3 TNRC6C ATP2A1

4.62e-04119434M607
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA2 CA5A

5.88e-0412432M671
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA2 CA5A

5.88e-0412432MM14574
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

HDAC11 HEY1 MIB1

7.26e-0458433M29616
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

AGO1 AGO3 TNRC6C

7.26e-0458433M11980
PathwayWP_MODULATORS_OF_TCR_SIGNALING_AND_T_CELL_ACTIVATION

AGO1 DGKA IKBKB

8.41e-0461433M42548
PathwayREACTOME_CA2_PATHWAY

AGO1 AGO3 TNRC6C

8.82e-0462433M27321
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

AGO1 AGO3 TNRC6C

9.24e-0463433M27862
PathwayBIOCARTA_AMAN_PATHWAY

MAN1A1 MAN1C1

9.31e-0415432M22009
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 AGO1 AGO3 TNRC6C

9.96e-04146434M27288
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS

MAN1A1 MAN1C1

1.06e-0316432M47632
PathwayREACTOME_SIGNALING_BY_NOTCH1

HDAC11 HEY1 MIB1

1.47e-0374433M616
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD1 RNF43

1.50e-0319432M47833
PathwayBIOCARTA_ERAD_PATHWAY

MAN1A1 MAN1C1

1.50e-0319432M22013
PathwayWP_TYPE_II_DIABETES_MELLITUS

PHKA2 IKBKB

2.02e-0322432M39658
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

AGO1 AGO3 TNRC6C

2.12e-0384433M27495
PathwayKEGG_NITROGEN_METABOLISM

CA2 CA5A

2.21e-0323432M4629
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

AGO1 AGO3 TNRC6C

2.58e-0390433M820
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO1 AGO3

2.61e-0325432M712
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

AGO1 AGO3 TNRC6C

1.88e-07762319470757
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

AGO1 AGO3 TNRC6C

1.88e-07762319383768
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

AGO1 AGO3 TNRC6C HERC2 ATP2A1

2.56e-077662527542412
Pubmed

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

AGO1 AGO3

3.13e-06262222318144
Pubmed

Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

AGO1 AGO3

9.37e-06362223665583
Pubmed

Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.

MAN1A1 MAN1C1

9.37e-06362210915796
Pubmed

The roles of individual mammalian argonautes in RNA interference in vivo.

AGO1 AGO3

9.37e-06362224992693
Pubmed

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.

MAN1A1 MAN1C1

9.37e-0636222406237
Pubmed

Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.

CA2 CA5A

9.37e-06362214600151
Pubmed

MiR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression.

SOD2 DNMT1

9.37e-06362227021683
Pubmed

Argonaute proteins in cardiac tissue contribute to the heart injury during viral myocarditis.

AGO1 AGO3

9.37e-06362226764146
Pubmed

Apoptosis-inducing factor regulates death in peripheral T cells.

TXNDC12 SOD2

9.37e-06362217617569
Pubmed

Argonaute2 is the catalytic engine of mammalian RNAi.

AGO1 AGO3

9.37e-06362215284456
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIPK3 PHKA2 ZNF106 HEY1 MAN1C1 ZNF451 HERC2 INVS

1.00e-0559162815231748
Pubmed

Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases.

MAN1A1 MAN1C1

1.87e-05462217727818
Pubmed

Molecular dissection of human Argonaute proteins by DNA shuffling.

AGO1 AGO3

1.87e-05462223748378
Pubmed

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.

AGO1 AGO3

1.87e-05462215260970
Pubmed

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.

MIB1 HERC2

1.87e-05462237074924
Pubmed

Slicing-independent RISC activation requires the argonaute PAZ domain.

AGO1 AGO3

1.87e-05462222795694
Pubmed

ATP-dependent human RISC assembly pathways.

AGO1 AGO3

1.87e-05462219966796
Pubmed

Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.

AGO1 AGO3

1.87e-05462218771919
Pubmed

A Requirement for Argonaute 4 in Mammalian Antiviral Defense.

AGO1 AGO3

1.87e-05462232049003
Pubmed

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.

AGO1 AGO3

3.12e-05562212526743
Pubmed

Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.

AGO1 AGO3

3.12e-05562219393748
Pubmed

Suppression of long non-coding RNA TNRC6C-AS1 protects against thyroid carcinoma through DNA demethylation of STK4 via the Hippo signalling pathway.

TNRC6C DNMT1

3.12e-05562230938030
Pubmed

Differential expression of components of the microRNA machinery during mouse organogenesis.

AGO1 AGO3

3.12e-05562216036130
Pubmed

Quantitative functions of Argonaute proteins in mammalian development.

AGO1 AGO3

3.12e-05562222474261
Pubmed

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.

AGO1 AGO3

3.12e-05562212414724
Pubmed

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.

AGO1 AGO3

3.12e-05562219324964
Pubmed

Hey1 and Hey2 are differently expressed during mouse tooth development.

HEY1 PAX9

3.12e-05562229155305
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

JPH1 PHKA2 ZNF106 ZNF451 PAFAH1B1 MIB1 ZNF324 HERC2 FBXO30 CA2

3.51e-051155621020360068
Pubmed

Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.

HIPK3 ZNF106 ZNF451

4.35e-053862328680062
Pubmed

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.

AGO1 AGO3

6.53e-05762228683311
Pubmed

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.

AGO1 AGO3

6.53e-05762234907157
Pubmed

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

AGO1 AGO3

6.53e-05762219536157
Pubmed

Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation.

MAN1A1 MAN1C1

8.69e-05862217121831
Pubmed

ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress.

TXNDC12 SOD2

8.69e-05862224191052
Pubmed

MicroRNA-500 sustains nuclear factor-κB activation and induces gastric cancer cell proliferation and resistance to apoptosis.

AGO1 IKBKB

8.69e-05862225595906
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

AGO1 AGO3

8.69e-05862219345100
Pubmed

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.

AGO1 AGO3

8.69e-05862229021386
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

FZD1 HDAC11 AGO1 AGO3 TXNDC12 DNMT1

1.09e-0442462621731673
Pubmed

Identification of eight members of the Argonaute family in the human genome.

AGO1 AGO3

1.12e-04962212906857
Pubmed

Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus.

PAX9 SBSN

1.12e-04962222567161
Pubmed

Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.

FZD1 HEY1

1.39e-041062217496152
Pubmed

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.

AGO1 AGO3

1.70e-041162222915799
Pubmed

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.

TUBB1 PAFAH1B1

1.70e-041162218331715
Pubmed

A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.

CA2 CA5A

2.04e-041262217362527
Pubmed

A human MAP kinase interactome.

HIPK3 RALGDS ZNF106 ZNF451 HERC2 FBXO30

2.29e-0448662620936779
Pubmed

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

AGO1 TNRC6C

2.81e-041462219716330
Pubmed

Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.

IKBKB ITGAL

2.81e-041462230131424
Pubmed

Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface.

MAN1A1 MAN1C1

3.23e-04156228892864
Pubmed

Microtubule-dependent apical polarization of basement membrane matrix mRNAs in mouse epithelial cells.

PAX9 TXNDC12

3.23e-041562238103869
Pubmed

Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling.

HEY1 MIB1

3.69e-041662216061358
Pubmed

Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.

GCM1 CA2

3.69e-041662218163532
Pubmed

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

AGO1 AGO3

3.69e-041662220102707
Pubmed

TRIM24 is an insulin-responsive regulator of P-bodies.

AGO1 AGO3 TNRC6C

4.02e-048062335803934
Pubmed

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

MAN1A1 MAN1C1

4.18e-04176222355006
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

DTNB HERC2

4.18e-041762223502783
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

NFE2L3 PAFAH1B1 MIB1

4.32e-048262331073041
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JPH1 NFE2L3 HEY1 ZNF451 MIB1 RNF10 HERC2 PREPL DNMT1

4.34e-04128562935914814
Pubmed

Low 8-oxo-7,8-dihydro-2'-deoxyguanosine levels and influence of genetic background in an Andean population exposed to high levels of arsenic.

SOD2 DNMT1

4.70e-041862219896490
Pubmed

Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome.

HEY1 PAX9

4.70e-041862231412026
Pubmed

Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function.

HEY1 GCM1

5.24e-041962228526753
Pubmed

SHARPIN negatively associates with TRAF2-mediated NFκB activation.

ZNF106 TXNDC12

5.24e-041962221829440
Pubmed

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.

HEY1 MIB1

5.82e-042062223314057
Pubmed

Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.

HEY1 GCM1

5.82e-042062221606200
Pubmed

Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.

MAN1A1 MAN1C1

5.82e-042062212560567
Pubmed

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.

HEY1 PAX9

5.82e-042062216169709
Pubmed

An obligatory role of mind bomb-1 in notch signaling of mammalian development.

HEY1 MIB1

6.42e-042162218043734
Pubmed

Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear.

HEY1 CA2

6.42e-042162224583262
Pubmed

Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.

MIB1 CA2

6.42e-042162219855135
Pubmed

Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.

MAN1A1 MAN1C1

7.06e-04226228673525
Pubmed

Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.

MAN1A1 MAN1C1

7.06e-04226229109416
Pubmed

Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.

MAN1A1 MAN1C1

7.06e-042262211530211
Pubmed

A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development.

CA2 CA5A

7.06e-042262223233153
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FZD1 TNRC6C HERC2 MRPL46 ZNF865 RNF43 TIAM2 TJP3

7.49e-04110562835748872
Pubmed

Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.

MAN1A1 MAN1C1

7.72e-04236221736542
Pubmed

Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.

MAN1A1 MAN1C1

7.72e-04236228093218
Pubmed

Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.

MAN1A1 MAN1C1

7.72e-04236223099781
Pubmed

Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.

MAN1A1 MAN1C1

7.72e-04236223264072
Pubmed

The DNA sequence and analysis of human chromosome 6.

TRERF1 MAN1A1 ZNF451 GCM1 FBXO30 SOD2

8.40e-0462262614574404
Pubmed

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice†.

HEY1 CA2

8.41e-042462237471646
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

MAN1A1 MAN1C1

9.14e-04256222283726
Pubmed

Human transcription factor protein interaction networks.

TRERF1 AGO1 AGO3 ZNF451 GCM1 TNRC6C PAX9 HERC2 YTHDF2

9.27e-04142962935140242
Pubmed

A dual role for Ikk alpha in tooth development.

PAX9 IKBKB

9.89e-042662214960276
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

MAN1A1 MAN1C1

9.89e-04266228218172
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

HIPK3 PHKA2 AGO1 AGO3 DTNB IKBKB YTHDF2

1.16e-0391062736736316
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

JPH1 MIB1 PREPL SBSN TXNDC12 TIAM2 CA2

1.20e-0391662732203420
Pubmed

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.

MIB1 SBSN CA2

1.21e-0311762336898370
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF106 MAN1A1 ZNF451 PAFAH1B1 SBSN TXNDC12 CA2 SOD2

1.29e-03120362829180619
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

HDAC11 AGO1 AGO3 MIB1 YTHDF2

1.41e-0346262531138677
Pubmed

The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci.

ITGAL CA2

1.41e-03316222165966
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

ZNF106 ZNF324 DNMT1

1.47e-0312562321654808
Pubmed

Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.

HEY1 MIB1

1.59e-033362216000382
Pubmed

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.

TUBB1 PAFAH1B1

1.69e-033462223533177
InteractionCNOT6L interactions

GPBP1L1 AGO1 AGO3 MIB1 TNRC6C YTHDF2

4.10e-0793626int:CNOT6L
InteractionATOH1 interactions

AGO1 AGO3 TNRC6C HERC2 ATP2A1

4.71e-0680625int:ATOH1
InteractionCPEB4 interactions

GPBP1L1 AGO1 AGO3 TNRC6C RNF43 YTHDF2

8.40e-06156626int:CPEB4
InteractionMKRN2 interactions

FZD1 AGO1 AGO3 MIB1 TNRC6C FITM2 RNF43 YTHDF2

2.27e-05385628int:MKRN2
InteractionTNRC6A interactions

GPBP1L1 AGO1 AGO3 MIB1 TNRC6C RNF43 YTHDF2

2.37e-05280627int:TNRC6A
InteractionTNRC6B interactions

GPBP1L1 AGO1 AGO3 MIB1 TNRC6C RNF43 YTHDF2

2.48e-05282627int:TNRC6B
InteractionFUBP3 interactions

AGO1 AGO3 TNRC6C PAX9 IKBKB RNF43 YTHDF2

3.46e-05297627int:FUBP3
InteractionTNRC6C interactions

GPBP1L1 AGO1 AGO3 TNRC6C YTHDF2

6.62e-05138625int:TNRC6C
InteractionCNOT7 interactions

GPBP1L1 AGO1 AGO3 TNRC6C YTHDF2

7.09e-05140625int:CNOT7
InteractionCNOT9 interactions

GPBP1L1 AGO1 AGO3 TNRC6C FITM2 YTHDF2

7.64e-05231626int:CNOT9
InteractionCTIF interactions

AGO1 AGO3 TNRC6C YTHDF2

9.29e-0577624int:CTIF
InteractionHELZ interactions

AGO1 AGO3 TNRC6C ANGPTL7 RNF43 YTHDF2

1.37e-04257626int:HELZ
InteractionDCP1A interactions

AGO1 AGO3 RCCD1 TNRC6C YTHDF2

1.58e-04166625int:DCP1A
InteractionGARRE1 interactions

GPBP1L1 AGO1 AGO3 TNRC6C YTHDF2

1.63e-04167625int:GARRE1
Cytoband8q21

JPH1 HEY1

1.17e-04126228q21
Cytoband1p35

MAN1C1 YTHDF2

1.39e-04136221p35
Cytoband19q13.42

SSC5D KIR3DX1 ZNF865

6.63e-0412562319q13.42
Cytoband6p12.1

ZNF451 GCM1

9.22e-04336226p12.1
CytobandEnsembl 112 genes in cytogenetic band chr6q25

ULBP1 TIAM2 SOD2

1.45e-03164623chr6q25
CytobandEnsembl 112 genes in cytogenetic band chr8q21

JPH1 HEY1 CA2

2.27e-03192623chr8q21
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DTNB MIB1 HERC2

9.97e-061843391
GeneFamilyMannosidases alpha class 1

MAN1A1 MAN1C1

3.31e-0544321193
GeneFamilyArgonaute/PIWI family

AGO1 AGO3

1.53e-048432408
GeneFamilyCarbonic anhydrases

CA2 CA5A

8.25e-0418432460
CoexpressionGSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP

TRERF1 ZNF106 AGO1 CLEC10A FITM2 PREPL

7.24e-06197626M3343
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

3.84e-061696257962165cab84af73d20b56eb70b1ed87c94025ef
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 RCCD1 PKHD1L1 ANGPTL7 SBSN

4.30e-06173625ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 RCCD1 PKHD1L1 ANGPTL7 SBSN

4.30e-061736253725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

4.55e-0617562521bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

5.08e-06179625d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

5.22e-06180625bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

5.22e-06180625839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 MAN1C1 CLEC10A ATP2A1 ANGPTL7

5.22e-0618062582965ed1b72a1873c24dd4553d39681596057316
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1C1 CLEC10A IKBKB ITGAL ATP2A1

5.36e-061816257286700396676fdc41d9723979b8b408177aceb9
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TUBB1 MAN1A1 ZNF451 FBXO30 CA2

7.32e-06193625305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TUBB1 MAN1A1 ZNF451 FBXO30 CA2

7.32e-06193625dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KIR3DX1 ITGAL CA5A

5.56e-05536232147787ed3de18b49f51a8518984c7b6ba9a8cef
ToppCellFetal_29-31_weeks-Immune-mast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TUBB1 NFE2L3 LINC00299 ANGPTL7

6.97e-051586240c27c475289c70b17b6a66fc71f628511c5f0ae1
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

RCCD1 MAN1C1 LYG2 INVS

7.32e-05160624a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2L3 PKHD1L1 ANGPTL7 SBSN

8.44e-05166624545f6c91102568791443717e522f89cb3bd1a070
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 PKHD1L1 ANGPTL7 SBSN

8.64e-051676247abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

JPH1 DTNB RNF43 FBXO30

8.64e-051676245c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 PKHD1L1 ANGPTL7 SBSN

8.64e-05167624d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellAdult-Immune-natural_killer_cell-D122|Adult / Lineage, Cell type, age group and donor

TRERF1 KIR3DX1 LINC00299 ITGAL

8.64e-05167624ff1ce3b1a2d91d2ad979f25899db4f4eeb865892
ToppCelldroplet-Lung-LUNG-30m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 CLEC10A ATP2A1 ANGPTL7

8.84e-05168624e156297a7515e785a9e79a9676700bd3a9d92b98
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 CLEC10A ATP2A1 ANGPTL7

8.84e-0516862432e0bc0873baa13027241063283ef26d2aab56f5
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC10A ATP2A1 ANGPTL7 TJP3

9.25e-05170624749144a1a869a6bf9acdd227184319083367dc3f
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC10A ATP2A1 ANGPTL7 TJP3

9.25e-0517062425d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLEC10A ATP2A1 ANGPTL7 TJP3

9.68e-05172624422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2L3 PKHD1L1 ANGPTL7 SBSN

9.68e-051726249a256db817c1af1802203cc88a55d608fb328c63
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLEC10A ATP2A1 ANGPTL7 TJP3

9.68e-051726241abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFE2L3 CLEC10A ATP2A1 ANGPTL7

9.90e-051736244f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFE2L3 CLEC10A ATP2A1 ANGPTL7

9.90e-051736249bbea566964281f47bf75d665b7d69ba8326e207
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TUBB1 ZNF451 PKHD1L1 CA2

1.03e-041756244c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NFE2L3 ZNF106 ZNF451 RNF43

1.03e-04175624334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1C1 CLEC10A ATP2A1 ANGPTL7

1.10e-04178624742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 CLEC10A ATP2A1 ANGPTL7

1.13e-041796241757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 CLEC10A ATP2A1 ANGPTL7

1.15e-0418062464f01494a4052186773720e10b4e7c724ff94547
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2L3 PKHD1L1 ANGPTL7 SBSN

1.15e-041806242ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 KIR3DX1 LINC00299 ITGAL

1.18e-041816248906ee8a7a1616dfe8c3b5c73988416641213629
ToppCellMS|World / Condition, Cell_class and T cell subcluster

LYG2 PKHD1L1 CA5A TJP3

1.18e-0418162499f054a586a95947528dc3fd8043c1bda5e74cc4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB1 LRFN4 FBXO30 CA2

1.18e-041816249dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB1 LRFN4 FBXO30 CA2

1.18e-0418162414c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB1 LRFN4 FBXO30 CA2

1.18e-04181624c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 DTNB MAN1C1 CA2

1.18e-04181624b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB1 LRFN4 FBXO30 CA2

1.18e-04181624fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCellAdult-Immune-natural_killer_cell-D231|Adult / Lineage, Cell type, age group and donor

TRERF1 KIR3DX1 LINC00299 ITGAL

1.20e-04182624dbf47bf4754d8ec3bc3ab1d5be7a6c47a7afbf43
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TUBB1 PKHD1L1 CA2 SOD2

1.25e-04184624213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 SSC5D LRFN4 MAN1C1

1.25e-04184624f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 CLEC10A ATP2A1 ANGPTL7

1.28e-0418562465dcb0a7ee64990a34a87c167b44497107f035ee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 DTNB MAN1C1 CA2

1.36e-0418862458ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellIPF-Lymphoid-NK|IPF / Disease state, Lineage and Cell class

TRERF1 KIR3DX1 LINC00299 ITGAL

1.39e-04189624d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

TRERF1 DGKA LINC00299 ITGAL

1.42e-041906240733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 DGKA LINC00299 ITGAL

1.42e-04190624b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCellAdult-Immune-natural_killer_cell|Adult / Lineage, Cell type, age group and donor

TRERF1 KIR3DX1 LINC00299 ITGAL

1.45e-04191624758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 KIR3DX1 LINC00299 ITGAL

1.45e-041916249b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCellIPF-Lymphoid-NK|World / Disease state, Lineage and Cell class

TRERF1 KIR3DX1 LINC00299 ITGAL

1.45e-04191624f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCellInfluenza_Severe-RBC|Influenza_Severe / Disease group and Cell class

ZNF451 RNF10 FBXO30 CA2

1.48e-04192624f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCellAdult-Immune-T_lymphocyte|Adult / Lineage, Cell type, age group and donor

TRERF1 DGKA LINC00299 ITGAL

1.51e-0419362426df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNF451 RNF10 ACKR2 FBXO30

1.51e-04193624be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellsevere_influenza-RBC|severe_influenza / disease group, cell group and cell class (v2)

ZNF451 RNF10 FBXO30 CA2

1.51e-04193624ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCellCOVID-19-lung-NK/NKT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 KIR3DX1 LINC00299 ITGAL

1.51e-04193624c24b44fcc92fff42ebba6f1aff91c7aaea179e56
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

TRERF1 DGKA LINC00299 ITGAL

1.54e-041946245c1dca33f382f37a7deb23e573578343c3b54986
ToppCellCOVID-19-lung-NK_cells|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 KIR3DX1 LINC00299 ITGAL

1.57e-041956243b716ec7acc9a37af6bf40e711a539ce58d74aa4
ToppCellCOVID-19-lung-NK/NKT|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 KIR3DX1 LINC00299 ITGAL

1.57e-041956243ab941a369e3815f338890b116dc77aefa054098
ToppCellwk_08-11-Hematologic-Myeloid-Myelocyte-like|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HIPK3 AGO1 RCCD1 DGKA

1.60e-041966244b88c96b737a747422674ad99c073b28e6febc7c
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LYG2 DGKA LINC00299 TNRC6C

1.63e-04197624e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

HDAC11 RNF10 PKHD1L1 FBXO30

1.66e-04198624dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCellT_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RALGDS DGKA TNRC6C ITGAL

1.66e-041986241ca6cd8e75891fdfaddbb4a7342eec9ca4d11e5d
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HDAC11 PKHD1L1 FBXO30 CA2

1.69e-04199624565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 DGKA LINC00299 ITGAL

1.69e-04199624fbdde57dd88656621801e65ee2818251588f3874
ToppCellInfluenza-Influenza_Severe-Others-RBC|Influenza_Severe / Disease, condition lineage and cell class

ZNF451 RNF10 FBXO30 CA2

1.69e-04199624da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell(2)_Fibroblasts-(24)_Fibro-5|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SSC5D ACKR2 ANGPTL7 SBSN

1.69e-041996246c0354f57883330c685a8d9d5d3014ace7eca584
ComputationalPol II transcription.

PHKA2 MIB1 HERC2 DNMT1

1.47e-0471414MODULE_308
DrugI7C

CA2 CA5A

2.18e-053622CID000069561
Drug4-hydroxymethylbenzenesulfonamide

CA2 CA5A

2.18e-053622CID010081162
Drug4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide

CA2 CA5A

2.18e-053622CID000031035
DrugAC1Q551A

CA2 CA5A

2.18e-053622CID011206245
DrugAC1NA7ER

CA2 CA5A

2.18e-053622CID004422372
Drug4-(2-aminoethyl)benzenesulfonamide

CA2 CA5A

2.18e-053622CID000169682
Drug6-hydroxy-1,3-benzothiazole-2-sulfonamide

CA2 CA5A

2.18e-053622CID006852129
Drug4-hydrazinobenzenesulfonamide

CA2 CA5A

2.18e-053622CID000078105
DrugCTK1B7592

CA2 CA5A

2.18e-053622CID009998322
Drug4-(2-hydroxyethyl)benzenesulfonamide

CA2 CA5A

2.18e-053622CID010375558
DrugAC1NQARZ

CA2 CA5A

2.18e-053622CID005172475
Drugsulpiride (SLP

CA2 CA5A

2.18e-053622CID003018597
Drug1-alpha-25-dihydroxycholecalciferol

FZD1 HDAC11 MIB1 GCM1 PAX9 ITGAL ATP2A1 RNF43 CA2 SOD2 CA5A

3.04e-059096211CID000002524
Drugperchlorate

ATP2A1 CA2 SOD2 DNMT1 CA5A

3.12e-05133625ctd:C494474
Drug3-Iodosulfanilamide

CA2 CA5A

4.36e-054622CID009861037
DrugNSC-700707

CA2 CA5A

4.36e-054622CID000134560
Drug3-bromosulfanilamide

CA2 CA5A

4.36e-054622CID003526523
DrugI-7B

CA2 CA5A

4.36e-054622CID000067136
DrugAC1Q511M

CA2 CA5A

4.36e-054622CID004687472
DrugPB311

CA2 CA5A

4.36e-054622CID001502014
Drugpotassium periodate

CA2 CA5A

7.26e-055622ctd:C037192
Drugsodium metasilicate

CA2 CA5A

7.26e-055622ctd:C025349
DrugIodates

CA2 CA5A

7.26e-055622ctd:D007452
Drug4-carbethoxyhexafluorobutyryl chloride

ACKR2 XPNPEP2

7.26e-055622CID000161251
Drugcobalt-60

TUBB1 DTNB XPNPEP2 PREPL CA2 SOD2 CA5A

8.97e-05390627CID000061492
DrugAC1L9R2Z

HIPK3 TUBB1 HDAC11 HERC2 SOD2

9.49e-05168625CID000453624
DrugEMD 486019

CA2 CA5A

1.09e-046622CID011245700
Drugorthanilamide

CA2 CA5A

1.09e-046622CID000072894
Drug2h15

CA2 CA5A

1.09e-046622CID010712038
DrugMG-262; Down 200; 0.1uM; MCF7; HT_HG-U133A

FZD1 LRFN4 MAN1A1 ZNF324 CA2

1.18e-041766257063_DN
Druggramicidin s

DTNB ATP2A1 SOD2

1.40e-0437623CID000073357
Drugchloric acid

CA2 CA5A

1.52e-047622ctd:C022842
DrugBaralyme

HEY1 SOD2

1.52e-047622CID000170176
DrugCarbonates

CA2 CA5A

1.52e-047622ctd:D002254
Drugsulfamic acid

CA2 CA5A

1.52e-047622ctd:C005741
DrugNitric Acid

CA2 CA5A

1.52e-047622ctd:D017942
Drugethoxzolamide

SI CA2 CA5A

1.77e-0440623CID000003295
DrugICI 182,780; Down 200; 1uM; MCF7; HG-U133A

FZD1 HIPK3 PHKA2 RALGDS MAN1A1

1.77e-04192625367_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A

HIPK3 HDAC11 MAN1A1 DGKA PAX9

1.95e-041966254319_UP
DrugAzathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A

FZD1 PHKA2 MAN1A1 AGO3 ZNF324

1.95e-041966252827_DN
DrugPyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A

FZD1 ZNF324 IKBKB RNF43 TJP3

1.95e-041966252751_DN
DrugRibavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A

HIPK3 TUBB1 ZNF324 PAX9 ITGAL

1.95e-041966256018_UP
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

HDAC11 MAN1C1 ZNF324 IKBKB RNF43

1.95e-041966257091_UP
DrugMeropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

FZD1 MAN1A1 ZNF324 SOD2 TJP3

2.00e-041976257180_UP
DrugProglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A

HIPK3 RALGDS MAN1A1 PAFAH1B1 IKBKB

2.00e-041976254337_DN
Druglixazinone

ZNF106 MIB1

2.02e-048622CID000058573
DrugBromates

CA2 CA5A

2.02e-048622ctd:D001959
Drugaminozolamide

CA2 CA5A

2.02e-048622CID000093505
DrugL-662,583

CA2 CA5A

2.02e-048622CID003082977
DrugL-643,799

CA2 CA5A

2.02e-048622CID000121595
Drugsezolamide

CA2 CA5A

2.02e-048622CID000060692
DrugDizocilpine maleate [77086-22-7]; Up 200; 11.8uM; PC3; HT_HG-U133A

RALGDS DTNB ULBP1 ACKR2 TJP3

2.05e-041986255746_UP
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

FZD1 PAFAH1B1 PAX9 RNF43 SOD2

2.10e-041996256882_DN
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A

FZD1 HIPK3 MAN1C1 DGKA ULBP1

2.10e-041996255436_UP
DrugIfenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A

HIPK3 ACKR2 PAX9 IKBKB RNF43

2.14e-042006257404_UP
DrugBendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

DTNB ZNF324 ULBP1 ACKR2 ATP2A1

2.14e-042006253840_UP
DrugChlorpyrifos

FZD1 ZNF106 DTNB PAFAH1B1 GCM1 PAX9 YTHDF2 FBXO30 CA2 SOD2

2.48e-049606210ctd:D004390
Drugtetrahydropyran

GPBP1L1 ACKR2 SOD2

2.51e-0445623CID000008894
DrugPyrones

IKBKB SOD2

2.59e-049622ctd:D011753
Drugqassa

CA2 CA5A

2.59e-049622CID003082191
Drug6-hydroxyethoxzolamide

CA2 CA5A

2.59e-049622CID000094706
DrugFebuxostat

IKBKB SOD2

2.59e-049622ctd:D000069465
Drugzinc methionine

SI SOD2

2.59e-049622CID000162430
DiseasePancreatic carcinoma

RNF43 SOD2

7.03e-0419612C0235974
DiseaseBreast Carcinoma

TRERF1 HEY1 RCCD1 HERC2 SOD2 DNMT1

8.49e-04538616C0678222
DiseaseCarcinoma, Pancreatic Ductal

HEY1 DNMT1

1.13e-0324612C0887833
DiseaseMalignant neoplasm of breast

TRERF1 HEY1 RCCD1 HERC2 IKBKB MAMDC4 SOD2 DNMT1

1.60e-031074618C0006142
DiseaseCarcinoma, Granular Cell

CA2 SOD2 DNMT1

1.80e-03116613C0205644
DiseaseAdenocarcinoma, Tubular

CA2 SOD2 DNMT1

1.80e-03116613C0205645
DiseaseAdenocarcinoma, Oxyphilic

CA2 SOD2 DNMT1

1.80e-03116613C0205642
DiseaseCarcinoma, Cribriform

CA2 SOD2 DNMT1

1.80e-03116613C0205643
DiseaseAdenocarcinoma, Basal Cell

CA2 SOD2 DNMT1

1.80e-03116613C0205641
DiseaseAdenocarcinoma

CA2 SOD2 DNMT1

1.80e-03116613C0001418

Protein segments in the cluster

PeptideGeneStartEntry
GVWNCHADFGGHGTI

ACKR2

191

O00590
KDGNSLHRHGDQAWG

LINC00299

51

Q6ZSB3
AQGQLAVWGAGGHRR

MAMDC4

1076

Q6UXC1
PHTGNRHNHWAGLYG

DNMT1

1501

P26358
RGWAINVGGGFHHCS

HDAC11

131

Q96DB2
GGGREVWFGFHQSVR

AGO1

191

Q9UL18
HPLGGGREVWFGFHQ

AGO3

191

Q9H9G7
IGHFNDPVHGGSWFR

ATP2A1

276

O14983
SWGGGRHGQLGHGTL

RCCD1

181

A6NED2
GHDNWVRGVLFHSGG

PAFAH1B1

336

P43034
GSIRGDFWLGNEHIH

ANGPTL7

196

O43827
YVAGHGWQHAGGTSL

PAX9

296

P55771
LGTGGFGNVIRWHNQ

IKBKB

21

O14920
MSQRSGGGTGNHRHW

GPBP1L1

106

Q9HC44
GGGTGNHRHWNGSFH

GPBP1L1

111

Q9HC44
SGTIYGWGHNHRGQL

HERC2

3951

O95714
GWGHNHRGQLGGIEG

HERC2

3956

O95714
GQWAGGMRHGYGVRQ

JPH1

131

Q9HDC5
VSVGHGNVGVNRGWF

LOXHD1

361

Q8IVV2
PFSASGGWGRAGHLH

NFE2L3

61

Q9Y4A8
HGGSNLWGDTRRPHG

DGKA

606

P23743
FGSGHQEWNGNFGHR

HIPK3

1061

Q9H422
FRHGVAHGQWLSGGQ

KIR3DX1

256

Q9H7L2
AHGQWLSGGQRHREA

KIR3DX1

261

Q9H7L2
VQSLQHGHGGWTDGM

MIB1

261

Q86YT6
RWGLGNGISIHHGEE

MALRD1

1116

Q5VYJ5
LKQFHFHWGAVNEGG

CA5A

126

P35218
FWTSNPQHGGGGHRG

FZD1

246

Q9UP38
HQEGGFWHGFDISGH

FITM2

141

Q8N6M3
RGHGGFPVTNFWRHD

GCM1

126

Q9NP62
FWRGHAGGPHSNQHQ

DTNB

271

O60941
LHHGGNKGQRWLGYE

RALGDS

86

Q12967
GNWVQHHVSVGGLGD

MAN1C1

376

Q9NR34
SHGGSVLQDGWDHRG

LYG2

106

Q86SG7
WGQHHVSVGGLGDSF

MAN1A1

401

P33908
AHAGLGHIPWGTVFG

HEY1

171

Q9Y5J3
FKNVHGDIHAGLNGW

FBXO30

536

Q8TB52
FGQGAHHGLSEGWKE

SBSN

206

Q6UWP8
RFGQGVHHGLSEGWK

SBSN

331

Q6UWP8
SDSGGHHIGWGERQG

PHKA2

1051

P46019
QDGHSLLHWAALGGN

INVS

421

Q9Y283
GDFSQAGNKGHHVWV

MRPL46

241

Q9H2W6
WGRGSGNNGVGNIHS

TNRC6C

311

Q9HCJ0
GNNGVGNIHSGAWGH

TNRC6C

316

Q9HCJ0
AGAQHPYAQGWGLSH

RNF43

406

Q68DV7
VHGNSGAGNNWAKGH

TUBB1

91

Q9H4B7
FAGSGRHAAHWLGDN

SI

591

P14410
GGGHWSQVQTIHGTQ

ITGAL

441

P20701
GNEGQLGLCHHRGWK

SSC5D

91

A1L4H1
IQFHFHWGSLDGQGS

CA2

91

P00918
WQGHGLGGGEDCAHF

CLEC10A

271

Q8IUN9
WSNFFGHLPGHLNQG

ZNF451

896

Q9Y4E5
GHLPGHLNQGTFIWG

ZNF451

901

Q9Y4E5
QWGIVDLSGHQHLFG

ZNF865

146

P0CJ78
AGGRGHHRMGAVWQE

ZNF324

216

O75467
KSLHGWGHGSNGAGY

TIAM2

41

Q8IVF5
RGQTGHFEGSGHGSW

RNF10

151

Q8N5U6
YCHVRGGGELGLQWH

PREPL

506

Q4J6C6
IRHNAVAGGTHFGFW

PKHD1L1

2571

Q86WI1
NGGGHINHSIFWTNL

SOD2

91

P04179
GPGQSHARGGHWLAV

TJP3

511

O95049
AHGHGRGSWQFLFNG

ULBP1

131

Q9BZM6
GTGHGIGNFLCVHEW

XPNPEP2

521

O43895
GHNGLGKGFGDHIHW

TXNDC12

26

O95881
HNHSNSGGGWLSNSG

ZNF106

176

Q9H2Y7
WVAPRNRGSGFGHNG

YTHDF2

351

Q9Y5A9
RQGGWGSHAGPGNHV

TRERF1

81

Q96PN7
GGAWARRSHSVHGGL

LRFN4

601

Q6PJG9