Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1 LRP2 CD320 STAB1	7.27e-08	16	52	4	GO:0005041
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1 LRP2 CD320 STAB1	2.37e-07	21	52	4	GO:0030228
GeneOntologyMolecularFunction	complement component C3b binding	CFH CFHR2 CR1	3.60e-06	12	52	3	GO:0001851
GeneOntologyMolecularFunction	opsonin binding	CFH CFHR2 CR1	3.68e-05	25	52	3	GO:0001846
GeneOntologyMolecularFunction	cargo receptor activity	LRP1 LRP2 CD320 STAB1	7.08e-05	85	52	4	GO:0038024
GeneOntologyMolecularFunction	complement binding	CFH CFHR2 CR1	7.83e-05	32	52	3	GO:0001848
GeneOntologyMolecularFunction	proteoglycan binding	COL2A1 CFH LRP1	3.18e-04	51	52	3	GO:0043394
GeneOntologyMolecularFunction	tumor necrosis factor receptor activity	TNFRSF11A TNFRSF4	4.32e-04	12	52	2	GO:0005031
GeneOntologyMolecularFunction	glycosaminoglycan binding	CFH CCN4 ECM2 PTCH1 STAB1	6.51e-04	268	52	5	GO:0005539
GeneOntologyMolecularFunction	death receptor activity	TNFRSF11A TNFRSF4	1.35e-03	21	52	2	GO:0005035
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL2A1 SSPOP MUC5AC MUC6	1.45e-03	188	52	4	GO:0005201
GeneOntologyMolecularFunction	sulfur compound binding	CFH CCN4 ECM2 LRP1 PTCH1	1.50e-03	323	52	5	GO:1901681
GeneOntologyMolecularFunction	heparin binding	CFH CCN4 ECM2 PTCH1	1.56e-03	192	52	4	GO:0008201
GeneOntologyMolecularFunction	scavenger receptor activity	LRP1 STAB1	2.24e-03	27	52	2	GO:0005044
GeneOntologyMolecularFunction	heparan sulfate proteoglycan binding	CFH LRP1	2.58e-03	29	52	2	GO:0043395
GeneOntologyMolecularFunction	lipoprotein particle binding	CD320 STAB1	3.75e-03	35	52	2	GO:0071813
GeneOntologyMolecularFunction	protein-lipid complex binding	CD320 STAB1	3.75e-03	35	52	2	GO:0071814
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	LRP1 LRP2	4.63e-03	39	52	2	GO:0070325
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP1 LRP2	6.45e-05	5	53	2	GO:1905167
GeneOntologyBiologicalProcess	chemoattraction of axon	LRP1 LRP2	6.45e-05	5	53	2	GO:0061642
GeneOntologyBiologicalProcess	activation of membrane attack complex	CFH CR1	9.65e-05	6	53	2	GO:0001905
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	RAG1 CCN4 NTRK2 BRINP2 LRP1 VWC2L LRP2 PAX4 TNFRSF11A PTCH1 CR1	1.26e-04	1141	53	11	GO:0045597
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LRP1 LRP2	1.35e-04	7	53	2	GO:1904352
GeneOntologyBiologicalProcess	regulation of complement activation, alternative pathway	CFH CR1	1.35e-04	7	53	2	GO:0030451
GeneOntologyCellularComponent	extracellular matrix	COL2A1 CCN4 LRRN3 FCGBP ZAN ECM2 MUC5B SSPOP MUC5AC MUC6 OTOG	6.14e-07	656	53	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL2A1 CCN4 LRRN3 FCGBP ZAN ECM2 MUC5B SSPOP MUC5AC MUC6 OTOG	6.33e-07	658	53	11	GO:0030312
GeneOntologyCellularComponent	keratin filament	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1	1.07e-04	97	53	4	GO:0045095
GeneOntologyCellularComponent	axonal growth cone	LRP1 LRP2 PTCH1	2.03e-04	45	53	3	GO:0044295
Domain	VWF_dom	COL2A1 CCN4 FCGBP ZAN ECM2 VWC2L MUC5B SSPOP MUC5AC MUC6 OTOG	1.27e-19	42	53	11	IPR001007
Domain	TIL_dom	FCGBP ZAN LRP2 MUC5B SSPOP MUC5AC MUC6 OTOG	7.17e-18	14	53	8	IPR002919
Domain	VWD	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 VWDE OTOG	3.06e-17	16	53	8	SM00216
Domain	VWF_type-D	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 VWDE OTOG	3.06e-17	16	53	8	IPR001846
Domain	VWFD	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 VWDE OTOG	3.06e-17	16	53	8	PS51233
Domain	VWD	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 VWDE OTOG	3.06e-17	16	53	8	PF00094
Domain	TIL	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 OTOG	7.69e-16	12	53	7	PF01826
Domain	C8	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 OTOG	7.69e-16	12	53	7	PF08742
Domain	VWC	COL2A1 CCN4 FCGBP ZAN ECM2 VWC2L MUC5B SSPOP MUC5AC	8.93e-16	38	53	9	SM00214
Domain	Unchr_dom_Cys-rich	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 OTOG	1.66e-15	13	53	7	IPR014853
Domain	C8	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 OTOG	1.66e-15	13	53	7	SM00832
Domain	VWC_out	FCGBP ZAN MUC5B SSPOP MUC5AC MUC6 OTOG	4.82e-14	19	53	7	SM00215
Domain	VWFC_1	COL2A1 CCN4 ZAN ECM2 VWC2L MUC5B SSPOP MUC5AC	6.89e-14	36	53	8	PS01208
Domain	VWFC_2	COL2A1 CCN4 ZAN ECM2 VWC2L MUC5B SSPOP MUC5AC	1.11e-13	38	53	8	PS50184
Domain	Cys_knot_C	CCN4 MUC5B SSPOP MUC5AC MUC6 OTOG	6.62e-11	25	53	6	IPR006207
Domain	CTCK_2	CCN4 MUC5B SSPOP MUC5AC MUC6 OTOG	6.62e-11	25	53	6	PS01225
Domain	CT	CCN4 MUC5B MUC5AC MUC6 OTOG	3.85e-09	22	53	5	SM00041
Domain	VWC	COL2A1 CCN4 ECM2 MUC5B MUC5AC	1.42e-08	28	53	5	PF00093
Domain	Keratin_B2	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1 KRTAP2-2	9.25e-08	40	53	5	PF01500
Domain	CTCK_1	CCN4 MUC5B SSPOP MUC5AC	1.72e-07	18	53	4	PS01185
Domain	EGF_3	ZAN ADAM23 LRP1 LRP2 SSPOP VWDE OTOG STAB1	3.03e-07	235	53	8	PS50026
Domain	EGF	FCGBP ZAN ADAM23 BRINP2 LRP1 LRP2 VWDE STAB1	3.03e-07	235	53	8	SM00181
Domain	EGF-like_dom	FCGBP ZAN ADAM23 LRP1 LRP2 VWDE OTOG STAB1	4.71e-07	249	53	8	IPR000742
Domain	KAP	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1 KRTAP2-2	6.20e-07	58	53	5	IPR002494
Domain	LDLR_class-A_CS	LRP1 LRP2 CD320 SSPOP	4.90e-06	40	53	4	IPR023415
Domain	EGF_1	ZAN ADAM23 LRP1 LRP2 SSPOP VWDE STAB1	7.35e-06	255	53	7	PS00022
Domain	Ldl_recept_a	LRP1 LRP2 CD320 SSPOP	7.90e-06	45	53	4	PF00057
Domain	-	LRP1 LRP2 CD320 SSPOP	8.63e-06	46	53	4	4.10.400.10
Domain	EGF_2	ZAN ADAM23 LRP1 LRP2 SSPOP VWDE STAB1	9.44e-06	265	53	7	PS01186
Domain	Glyco_hormone_CN	CCN4 MUC5B MUC5AC	9.58e-06	15	53	3	IPR006208
Domain	Cys_knot	CCN4 MUC5B MUC5AC	9.58e-06	15	53	3	PF00007
Domain	LDLRA_1	LRP1 LRP2 CD320 SSPOP	1.02e-05	48	53	4	PS01209
Domain	LDLRA_2	LRP1 LRP2 CD320 SSPOP	1.11e-05	49	53	4	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LRP2 CD320 SSPOP	1.11e-05	49	53	4	IPR002172
Domain	LDLa	LRP1 LRP2 CD320 SSPOP	1.11e-05	49	53	4	SM00192
Domain	TILa	FCGBP ZAN	2.37e-05	3	53	2	PF12714
Domain	TILa_dom	FCGBP ZAN	2.37e-05	3	53	2	IPR025615
Domain	TNFR_c6	TNFRSF8 TNFRSF11A TNFRSF4	3.20e-05	22	53	3	PF00020
Domain	TNFR	TNFRSF8 TNFRSF11A TNFRSF4	5.36e-05	26	53	3	SM00208
Domain	TNFR_NGFR_1	TNFRSF8 TNFRSF11A TNFRSF4	7.48e-05	29	53	3	PS00652
Domain	TNFR_NGFR_2	TNFRSF8 TNFRSF11A TNFRSF4	7.48e-05	29	53	3	PS50050
Domain	EGF-like_CS	ZAN ADAM23 LRP1 LRP2 VWDE STAB1	9.31e-05	261	53	6	IPR013032
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF8 TNFRSF11A TNFRSF4	1.11e-04	33	53	3	IPR001368
Domain	WxxW_domain	MUC5B MUC5AC	1.18e-04	6	53	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	1.18e-04	6	53	2	PF13330
Domain	Keratin_B2_2	KRTAP2-3 KRTAP10-10 KRTAP2-2	1.83e-04	39	53	3	PF13885
Domain	Sushi	CFH CFHR2 CR1	4.32e-04	52	53	3	PF00084
Domain	EGF	ZAN LRP1 LRP2 STAB1	4.48e-04	126	53	4	PF00008
Domain	CCP	CFH CFHR2 CR1	4.83e-04	54	53	3	SM00032
Domain	SUSHI	CFH CFHR2 CR1	5.38e-04	56	53	3	PS50923
Domain	Sushi_SCR_CCP_dom	CFH CFHR2 CR1	5.67e-04	57	53	3	IPR000436
Domain	EGF_extracell	ADAM23 LRP2 STAB1	6.59e-04	60	53	3	IPR013111
Domain	EGF_2	ADAM23 LRP2 STAB1	6.59e-04	60	53	3	PF07974
Domain	Ldl_recept_b	LRP1 LRP2	7.03e-04	14	53	2	PF00058
Domain	LDLRB	LRP1 LRP2	7.03e-04	14	53	2	PS51120
Domain	TSP_1	CCN4 THSD7A SSPOP	7.60e-04	63	53	3	PF00090
Domain	LY	LRP1 LRP2	8.10e-04	15	53	2	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP2	8.10e-04	15	53	2	IPR000033
Domain	TSP1	CCN4 THSD7A SSPOP	8.32e-04	65	53	3	SM00209
Domain	TSP1_rpt	CCN4 THSD7A SSPOP	8.32e-04	65	53	3	IPR000884
Domain	TSP1	CCN4 THSD7A SSPOP	8.32e-04	65	53	3	PS50092
Domain	Growth_fac_rcpt_	CCN4 LRP1 LRP2 STAB1	9.98e-04	156	53	4	IPR009030
Domain	Znf_RING_CS	RAG1 RNF144A CHFR TRIM77	1.17e-03	163	53	4	IPR017907
Domain	LRR_8	LRRN3 ECM2 NTRK2 LRRC7	1.40e-03	171	53	4	PF13855
Domain	cEGF	LRP1 LRP2	2.46e-03	26	53	2	IPR026823
Domain	cEGF	LRP1 LRP2	2.46e-03	26	53	2	PF12662
Domain	ArfGap	ASAP2 ARAP2	3.05e-03	29	53	2	SM00105
Domain	ArfGap	ASAP2 ARAP2	3.05e-03	29	53	2	PF01412
Domain	ARFGAP	ASAP2 ARAP2	3.05e-03	29	53	2	PS50115
Domain	ArfGAP	ASAP2 ARAP2	3.05e-03	29	53	2	IPR001164
Domain	LRR_1	LRRN3 ECM2 NTRK2 LRRC7	3.44e-03	219	53	4	PF00560
Domain	zf-C3HC4	RAG1 RNF144A CHFR TRIM77	3.67e-03	223	53	4	PF00097
Domain	EGF_CA	LRP1 LRP2 STAB1	5.02e-03	122	53	3	SM00179
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD7A MUC5B SSPOP MUC5AC MUC6	1.47e-06	68	41	5	M27303
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC5B MUC5AC MUC6	1.25e-05	16	41	3	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC5B MUC5AC MUC6	1.51e-05	17	41	3	M27412
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A MUC5B SSPOP MUC5AC MUC6	1.51e-05	109	41	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A MUC5B SSPOP MUC5AC MUC6	1.65e-05	111	41	5	M27416
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC MUC6	2.93e-05	21	41	3	MM15706
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC MUC6	3.88e-05	23	41	3	M556
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD7A MUC5B SSPOP MUC5AC MUC6	5.59e-05	143	41	5	M27275
Pathway	REACTOME_DECTIN_2_FAMILY	MUC5B MUC5AC MUC6	5.67e-05	26	41	3	M27483
Pathway	REACTOME_KERATINIZATION	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1 KRTAP2-2	7.71e-05	153	41	5	MM15343
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD7A MUC5B CD320 SSPOP MUC5AC MUC6	7.83e-05	250	41	6	M27554
Pathway	KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN	CFH CR1	8.21e-05	5	41	2	M47875
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL2A1 KRTAP2-3 ADAM23 KRTAP2-4 KRTAP10-10 KRTAP2-1 SEMA4A KRTAP2-2	8.28e-05	502	41	8	MM14537
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFH CFHR2	1.23e-04	6	41	2	M47880
Pathway	WP_COMPLEMENT_SYSTEM	CFH CFHR2 LRP2 CR1	1.69e-04	96	41	4	M39581
Pathway	REACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY	LRP2 CD320	1.72e-04	7	41	2	MM15703
Pathway	REACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY	LRP2 CD320	2.29e-04	8	41	2	M45025
Pathway	KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR	LRP2 PTCH1	2.93e-04	9	41	2	M47893
Pathway	REACTOME_KERATINIZATION	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1 KRTAP2-2	3.94e-04	217	41	5	M27640
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC5B MUC5AC MUC6	6.96e-04	60	41	3	MM15636
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC5B MUC5AC MUC6	7.67e-04	62	41	3	M546
Pathway	REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM	LRP2 CD320	8.46e-04	15	41	2	MM14762
Pathway	BIOCARTA_ARAP_PATHWAY	ASAP2 ARAP2	1.09e-03	17	41	2	M2482
Pathway	PID_HEDGEHOG_2PATHWAY	LRP2 PTCH1	1.84e-03	22	41	2	M211
Pathway	REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM	LRP2 CD320	1.84e-03	22	41	2	M27084
Pathway	REACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS	TNFRSF8 TNFRSF4	2.57e-03	26	41	2	MM15270
Pathway	REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY	TNFRSF8 TNFRSF11A TNFRSF4	2.79e-03	97	41	3	MM15268
Pathway	REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY	TNFRSF8 TNFRSF11A TNFRSF4	3.12e-03	101	41	3	M27552
Pathway	REACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS	TNFRSF8 TNFRSF4	3.19e-03	29	41	2	M27555
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	THSD7A LRP1 LRP2 SSPOP MUC5AC MUC6	1.24e-09	71	53	6	33541421
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC MUC6	1.34e-08	4	53	3	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC5AC MUC6	1.34e-08	4	53	3	14984930
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC5AC MUC6	1.34e-08	4	53	3	29869461
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC MUC6	1.34e-08	4	53	3	23807779
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC5AC MUC6	1.34e-08	4	53	3	12676567
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC5AC MUC6	6.66e-08	6	53	3	19110483
Pubmed	Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.	KRTAP2-3 KRTAP2-4 KRTAP2-1 KRTAP2-2	3.06e-07	37	53	4	11279113
Pubmed	Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.	LRP1 LRP2 MUC5B MUC5AC	8.16e-07	47	53	4	11208732
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	2.28e-06	2	53	2	7513696
Pubmed	Synergistic OX40 and CD30 signals sustain CD8+ T cells during antigenic challenge.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	19609980
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	2.28e-06	2	53	2	34058148
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	2.28e-06	2	53	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	2.28e-06	2	53	2	14988081
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	2.28e-06	2	53	2	34445520
Pubmed	Maternofetal transport of vitamin B12: role of TCblR/CD320 and megalin.	LRP2 CD320	2.28e-06	2	53	2	28351841
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	2.28e-06	2	53	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	2.28e-06	2	53	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	2.28e-06	2	53	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	2.28e-06	2	53	2	22391959
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	2.28e-06	2	53	2	14718370
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	2.28e-06	2	53	2	35776514
Pubmed	Expression of CD30 and Ox40 on T lymphocyte subsets is controlled by distinct regulatory mechanisms.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	14634058
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	2.28e-06	2	53	2	24327612
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	2.28e-06	2	53	2	21653907
Pubmed	Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.	MUC5AC MUC6	2.28e-06	2	53	2	28321513
Pubmed	Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs.	MUC5AC MUC6	2.28e-06	2	53	2	9422745
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	2.28e-06	2	53	2	36427316
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	2.28e-06	2	53	2	28607090
Pubmed	Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.	MUC5AC MUC6	2.28e-06	2	53	2	12360467
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	2.28e-06	2	53	2	23272068
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	2.28e-06	2	53	2	31030254
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	2.28e-06	2	53	2	27729120
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	2.28e-06	2	53	2	23527003
Pubmed	Combination blockade of OX40L and CD30L inhibits allergen-driven memory TH2 cell reactivity and lung inflammation.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	33160971
Pubmed	A diametric role for OX40 in the response of effector/memory CD4+ T cells and regulatory T cells to alloantigen.	RAG1 TNFRSF4	2.28e-06	2	53	2	23817421
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	2.28e-06	2	53	2	16540890
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	2.28e-06	2	53	2	36111525
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	2.28e-06	2	53	2	27845589
Pubmed	The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.	LRP2 CD320	2.28e-06	2	53	2	23430977
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	2.28e-06	2	53	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	2.28e-06	2	53	2	26871672
Pubmed	Aggregated low-density lipoprotein induces LRP1 stabilization through E3 ubiquitin ligase CHFR downregulation in human vascular smooth muscle cells.	CHFR LRP1	2.28e-06	2	53	2	23241409
Pubmed	Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	15778343
Pubmed	Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.	MUC5AC MUC6	2.28e-06	2	53	2	11988092
Pubmed	Different role of CD30 in the development of acute and chronic airway inflammation in a murine asthma model.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	19544310
Pubmed	Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes.	CFH CR1	2.28e-06	2	53	2	2977721
Pubmed	Blockade of tumor necrosis factor superfamily members CD30 and OX40 abrogates disease activity in murine immune-mediated glomerulonephritis.	TNFRSF8 TNFRSF4	2.28e-06	2	53	2	33785369
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	2.28e-06	2	53	2	32348677
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	2.28e-06	2	53	2	11587997
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	2.28e-06	2	53	2	24332705
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	2.28e-06	2	53	2	34656442
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5B MUC5AC MUC6	2.68e-06	18	53	3	18834073
Pubmed	Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.	COL2A1 SPRY4 PTCH1	3.74e-06	20	53	3	23633963
Pubmed	Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.	TNFRSF8 TNFRSF11A TNFRSF4	5.04e-06	22	53	3	15301860
Pubmed	Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice.	COL2A1 SPRY4 PTCH1	5.04e-06	22	53	3	28027321
Pubmed	Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung.	COL2A1 SPRY4 PTCH1	6.61e-06	24	53	3	19097117
Pubmed	Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.	RAG1 CCN4	6.83e-06	3	53	2	28783045
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	6.83e-06	3	53	2	27776277
Pubmed	RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.	RAG1 TNFRSF4	6.83e-06	3	53	2	32169842
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	6.83e-06	3	53	2	29286856
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CFH CR1	6.83e-06	3	53	2	3782802
Pubmed	Mucin expression in reactive gastropathy: an immunohistochemical analysis.	MUC5AC MUC6	6.83e-06	3	53	2	17227128
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	6.83e-06	3	53	2	36675209
Pubmed	Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate.	RAG1 STAB1	6.83e-06	3	53	2	29898394
Pubmed	Mucin phenotype expression of gastric neuroendocrine neoplasms: analysis of histopathology and carcinogenesis.	MUC5AC MUC6	6.83e-06	3	53	2	23828549
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	6.83e-06	3	53	2	29802623
Pubmed	Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.	RAG1 LRP1	6.83e-06	3	53	2	24778318
Pubmed	Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.	CFH CR1	6.83e-06	3	53	2	20702729
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC5AC MUC6	6.83e-06	3	53	2	18825309
Pubmed	Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).	CFH CR1	6.83e-06	3	53	2	9988761
Pubmed	Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice.	TNFRSF8 TNFRSF4	6.83e-06	3	53	2	21788408
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC5AC MUC6	6.83e-06	3	53	2	18300795
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	6.83e-06	3	53	2	34158522
Pubmed	A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer.	MUC5AC MUC6	6.83e-06	3	53	2	19924550
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	6.83e-06	3	53	2	29604272
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	6.83e-06	3	53	2	19596978
Pubmed	RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.	RAG1 TNFRSF11A	6.83e-06	3	53	2	17502664
Pubmed	Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity.	TNFRSF8 TNFRSF4	6.83e-06	3	53	2	28646041
Pubmed	Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.	RAG1 PTCH1	6.83e-06	3	53	2	19297414
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	6.83e-06	3	53	2	19556605
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	6.83e-06	3	53	2	21455588
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	6.83e-06	3	53	2	20422702
Pubmed	The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells.	RAG1 TNFRSF11A	6.83e-06	3	53	2	29858011
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	6.83e-06	3	53	2	19718741
Pubmed	PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud.	COL2A1 SPRY4 PTCH1	9.52e-06	27	53	3	27827819
Pubmed	Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.	CFH CFHR2	1.36e-05	4	53	2	24333077
Pubmed	Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.	CFH CR1	1.36e-05	4	53	2	27165610
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC5AC MUC6	1.36e-05	4	53	2	33154304
Pubmed	Contribution of CD30/CD153 but not of CD27/CD70, CD134/OX40L, or CD137/4-1BBL to the optimal induction of protective immunity to Mycobacterium avium.	TNFRSF8 TNFRSF4	1.36e-05	4	53	2	15316035
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	1.36e-05	4	53	2	31582416
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC5AC MUC6	1.36e-05	4	53	2	24901817
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	1.36e-05	4	53	2	12413896
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	1.36e-05	4	53	2	25638393
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC5AC MUC6	1.36e-05	4	53	2	36367122
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	1.36e-05	4	53	2	21097527
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	1.36e-05	4	53	2	22269464
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	1.36e-05	4	53	2	23249391
Pubmed	Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.	LRP1 PTCH1	1.36e-05	4	53	2	15769472
Pubmed	Distinct spatiotemporal roles of hedgehog signalling during chick and mouse cranial base and axial skeleton development.	COL2A1 PTCH1	1.36e-05	4	53	2	23009899
Interaction	ZDHHC15 interactions	THSD7A LRP1 LRP2 SSPOP MUC5AC MUC6	7.23e-07	125	51	6	int:ZDHHC15
Interaction	SPATA3 interactions	KRTAP2-3 KRTAP2-4 VWC2L	2.98e-05	24	51	3	int:SPATA3
Interaction	MANBA interactions	CFH SIAE BRINP2 IGFL3	3.87e-05	75	51	4	int:MANBA
Interaction	NTF3 interactions	NTRK2 LRP1 VWDE	4.28e-05	27	51	3	int:NTF3
Interaction	LCE1C interactions	KRTAP2-3 KRTAP2-4 KRTAP10-10 VWC2L	4.30e-05	77	51	4	int:LCE1C
Interaction	OTX1 interactions	CCN4 KRTAP2-3 KRTAP2-4 SPRY4 VWC2L	4.45e-05	155	51	5	int:OTX1
Interaction	CFHR1 interactions	CFH CFHR2	1.31e-04	7	51	2	int:CFHR1
Interaction	ZNF264 interactions	KRTAP2-3 KRTAP2-4 LRP2	1.52e-04	41	51	3	int:ZNF264
Interaction	HOXA1 interactions	CCN4 KRTAP2-3 KRTAP2-4 KRTAP10-10 SPRY4 VWC2L	2.68e-04	356	51	6	int:HOXA1
Interaction	GNG8 interactions	CFH FCGBP MUC5B MUC5AC	2.81e-04	125	51	4	int:GNG8
Interaction	BDNF interactions	NTRK2 LRP1 PTCH1	2.92e-04	51	51	3	int:BDNF
Interaction	THBS1 interactions	COL2A1 CFH LRP1 LRP2	2.99e-04	127	51	4	int:THBS1
Cytoband	17q21.2	KRTAP2-3 KRTAP2-4 KRTAP2-2	7.53e-05	70	53	3	17q21.2
Cytoband	9q22.3	ECM2 PTCH1	8.57e-05	12	53	2	9q22.3
Cytoband	11p15.5	MUC5B MUC5AC MUC6	3.53e-04	118	53	3	11p15.5
Cytoband	7p21.3	THSD7A VWDE	4.85e-04	28	53	2	7p21.3
Cytoband	1p36	TNFRSF8 TNFRSF4	1.37e-03	47	53	2	1p36
Cytoband	1q32	CFH CR1	1.49e-03	49	53	2	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRTAP2-3 KRTAP2-4 KRTAP2-1 KRTAP2-2	2.19e-03	473	53	4	chr17q21
Cytoband	Ensembl 112 genes in cytogenetic band chr1q31	CFH CFHR2	3.44e-03	75	53	2	chr1q31
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	MUC5B MUC5AC MUC6 OTOG	4.10e-03	564	53	4	chr11p15
Cytoband	Ensembl 112 genes in cytogenetic band chr7p21	THSD7A VWDE	4.80e-03	89	53	2	chr7p21
GeneFamily	Keratin associated proteins	KRTAP2-3 KRTAP2-4 KRTAP10-10 KRTAP2-1 KRTAP2-2	3.55e-06	109	39	5	619
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC MUC6	1.20e-05	21	39	3	648
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF8 TNFRSF11A TNFRSF4	3.26e-05	29	39	3	782
GeneFamily	Complement system\|Sushi domain containing	CFH CFHR2 CR1	6.31e-05	36	39	3	492
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	TNFRSF8 LRP1 TNFRSF11A CD320 CR1 TNFRSF4	1.83e-04	394	39	6	471
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH CFHR2 CR1	2.50e-04	57	39	3	1179
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2	3.48e-04	13	39	2	634
GeneFamily	ArfGAPs	ASAP2 ARAP2	2.29e-03	33	39	2	395
GeneFamily	Ring finger proteins	RAG1 RNF144A CHFR TRIM77	2.83e-03	275	39	4	58
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ASAP2 RASA3 ARAP2	9.85e-03	206	39	3	682
Coexpression	NABA_MATRISOME	COL2A1 CCN4 ADAM23 ECM2 BRINP2 VWC2L MUC5B SEMA4A SSPOP MUC5AC MUC6 VWDE OTOG	7.51e-08	1008	53	13	MM17056
Coexpression	NABA_MATRISOME	COL2A1 CCN4 ADAM23 ECM2 BRINP2 VWC2L MUC5B SEMA4A SSPOP MUC5AC MUC6 VWDE OTOG	9.22e-08	1026	53	13	M5889
Coexpression	JAEGER_METASTASIS_DN	CFH GABRE FCGBP NTRK2 PTCH1 ARAP2	1.40e-05	260	53	6	M10702
Coexpression	NABA_CORE_MATRISOME	COL2A1 CCN4 ECM2 SSPOP VWDE OTOG	1.73e-05	270	53	6	MM17057
Coexpression	NABA_CORE_MATRISOME	COL2A1 CCN4 ECM2 SSPOP VWDE OTOG	1.92e-05	275	53	6	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	CCN4 ECM2 SSPOP VWDE OTOG	4.21e-05	191	53	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	CCN4 ECM2 SSPOP VWDE OTOG	4.76e-05	196	53	5	M3008
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_PROXIMAL_SECRETORY_1_CELL	CFH FCGBP BRINP2 MUC5B	7.08e-05	109	53	4	M45707
Coexpression	DESCARTES_FETAL_SPLEEN_MEGAKARYOCYTES	GABRE ASAP2 RASA3 NBEAL2	8.43e-05	114	53	4	M40293
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOPC	COL2A1 RNF144A SPRY4 BRINP2 LRP1 SSPOP	9.39e-05	366	53	6	M39052
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL3	LRRN3 THSD7A NTRK2 LRP1 LRP2 SSPOP ARAP2	1.50e-04	574	53	7	M39056
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZAN LRP2 MUC5B SSPOP OTOG	8.44e-08	184	53	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZAN LRP2 MUC5B SSPOP OTOG	8.44e-08	184	53	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZAN LRP2 MUC5B SSPOP OTOG	8.44e-08	184	53	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Mild-CD4+_T\|Mild / Disease group and Cell class	CFH RASA3 ADAM23 NTRK2 CR1 TNFRSF4	8.71e-08	185	53	6	c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCell	Caecum-(6)_Macrophage-(61)_LYVE1_Macrophage\|Caecum / shred on region, Cell_type, and subtype	ASAP2 FCGBP LRP1 TNFRSF11A SSPOP STAB1	1.30e-07	198	53	6	e684c3934c163aef4d284b69435832d2c9614f2a
ToppCell	Caecum-Macrophage-LYVE1_Macrophage\|Caecum / Region, Cell class and subclass	ASAP2 FCGBP LRP1 TNFRSF11A SSPOP STAB1	1.30e-07	198	53	6	a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GJA3 FCGBP SCN10A LRP2	7.97e-07	60	53	4	aa75fef294803ec6396c7d2c1f51d52bc4a5b43f
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GJA3 FCGBP SCN10A LRP2	7.97e-07	60	53	4	069fbabfd0e48e5809ff01a026439fd0bd017779
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL2A1 GABRE THSD7A PAX4 OTOG	8.22e-07	145	53	5	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 THSD7A ECM2 LRP1 MUC5AC	1.55e-06	165	53	5	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL2A1 MUC5B TNFRSF11A MUC5AC MUC6	1.75e-06	169	53	5	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 ECM2 SPRY4 LRP1	2.45e-06	181	53	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 ECM2 SPRY4 LRP1	2.45e-06	181	53	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH GABRE CCN4 RNF144A PTCH1	3.02e-06	189	53	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH GABRE CCN4 RNF144A PTCH1	3.02e-06	189	53	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FCGBP TNFRSF11A CR1 MUC6 STAB1	3.02e-06	189	53	5	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A LRP1 PTCH1	3.26e-06	192	53	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 ECM2 RNF144A LRP1	3.26e-06	192	53	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	Enterocyte_Progenitors-C_06\|Enterocyte_Progenitors / shred on cell type and cluster	CFH FCGBP MUC5B MUC5AC MUC6	3.26e-06	192	53	5	b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A LRP1 PTCH1	3.26e-06	192	53	5	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	C_06\|World / shred on cell type and cluster	CFH MUC5B CD320 MUC5AC MUC6	3.43e-06	194	53	5	5cb42e09f380c4468cdc603ec0c3de35eadd3213
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP IGFL3 TNFRSF11A CR1 STAB1	3.43e-06	194	53	5	48c37251518f96524807b5bd1bbc2820637666ad
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP IGFL3 TNFRSF11A CR1 STAB1	3.43e-06	194	53	5	7b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A LRP1 PTCH1	3.43e-06	194	53	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP IGFL3 TNFRSF11A CR1 STAB1	3.43e-06	194	53	5	435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCN4 ECM2 NTRK2 LRP1	3.61e-06	196	53	5	fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A LRP1 PTCH1	3.70e-06	197	53	5	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A LRP1 PTCH1	3.70e-06	197	53	5	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Bronchus_Control_(B.)-Immune-TX-MoAM-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FCGBP LRP1 TNFRSF11A CR1 STAB1	3.89e-06	199	53	5	fb63885273d906a85fef178d859d20a311eb8a72
ToppCell	Sigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage\|Sigmoid / shred on region, Cell_type, and subtype	ASAP2 LRP1 TNFRSF11A CR1 STAB1	3.98e-06	200	53	5	bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
ToppCell	Sigmoid-Macrophage-LYVE1_Macrophage\|Sigmoid / Region, Cell class and subclass	ASAP2 LRP1 TNFRSF11A CR1 STAB1	3.98e-06	200	53	5	851a1b372ddbec522829069e69ed36a1f4832131
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP2-3 KRTAP10-10 KRTAP2-1 KRTAP2-2	2.75e-05	146	53	4	522c32103c24fc26836bb5b642083904682d9292
ToppCell	COVID-CD4-antiviral_CD4\|COVID / Condition, Cell_class and T cell subcluster	CFH LRRN3 PRDM4 TNFRSF4	3.48e-05	155	53	4	7e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAM23 TNFRSF11A SSPOP TNFRSF4	3.57e-05	156	53	4	095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCell	facs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG1 TNFRSF8 RNF144A ARAP2	3.57e-05	156	53	4	bb64bf520cb74897a01c64924a85a1550df2b801
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAM23 TNFRSF11A SSPOP TNFRSF4	3.57e-05	156	53	4	29b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GJA3 SCN10A MUC5AC	4.09e-05	56	53	3	af55596513ddbe60b08648b27e41a7b65e3da58c
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAG1 TNFRSF8 RNF144A ARAP2	4.13e-05	162	53	4	1f1b93394b1f27cbb76b369c19b9313609edd577
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIAE FCGBP MUC5B MUC5AC	4.55e-05	166	53	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIAE FCGBP MUC5B MUC5AC	4.55e-05	166	53	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	Club_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CFH KRTAP2-4 MUC5B MUC6	4.55e-05	166	53	4	a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCell	COPD-Lymphoid-ILC_B\|COPD / Disease state, Lineage and Cell class	RNF144A PAX4 TNFRSF11A TNFRSF4	4.55e-05	166	53	4	7609671e453280c6e522e9f659c06aab8be81945
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIAE FCGBP MUC5B MUC5AC	4.55e-05	166	53	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFH FCGBP MUC5B MUC5AC	4.65e-05	167	53	4	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NBEAL2 RNF144A LRP1	4.76e-05	168	53	4	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH GABRE FCGBP MUC5B	4.87e-05	169	53	4	aec97583b23112060437b619cb429dc32f29285f
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	KRTAP2-4 MUC5B MUC5AC MUC6	5.22e-05	172	53	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	PND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFH TNFRSF11A SEMA4A STAB1	5.22e-05	172	53	4	9a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 TNFRSF11A SSPOP TNFRSF4	5.22e-05	172	53	4	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM23 TNFRSF11A SSPOP TNFRSF4	5.22e-05	172	53	4	48d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 TNFRSF11A SSPOP TNFRSF4	5.22e-05	172	53	4	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GABRE FCGBP MUC5B VWDE	5.34e-05	173	53	4	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	FCGBP LRP1 SEMA4A STAB1	5.46e-05	174	53	4	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	CFH TNFRSF8 LRP1 CR1	5.58e-05	175	53	4	2eca4c168dea2017ea0e383006e28abed22f32ec
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH FCGBP MUC5B MUC5AC	5.58e-05	175	53	4	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 LRP1 LRRC7	5.58e-05	175	53	4	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH CFHR2 TNFRSF11A STAB1	5.58e-05	175	53	4	53e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH FCGBP MUC5B MUC5AC	5.58e-05	175	53	4	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 LRP2 SSPOP OTOG	5.71e-05	176	53	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FCGBP LRP1 CR1 STAB1	5.83e-05	177	53	4	382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP MUC5B TNFRSF11A MUC5AC	5.83e-05	177	53	4	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	facs-Lung-EPCAM-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 TNFRSF11A SEMA4A TNFRSF4	5.83e-05	177	53	4	d445167dae956e641386f84ab3ae9f47c089e09a
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFH FCGBP MUC5B MUC5AC	5.83e-05	177	53	4	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FCGBP MUC5B MUC5AC	5.83e-05	177	53	4	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FCGBP MUC5B MUC5AC	5.83e-05	177	53	4	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFH FCGBP MUC5B MUC5AC	5.83e-05	177	53	4	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A TNFRSF8 VWDE TNFRSF4	5.96e-05	178	53	4	888add8935ef3aef9b6693c5698e9d1842e66337
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A TNFRSF8 VWDE TNFRSF4	5.96e-05	178	53	4	43eda32af2e5e28a92421612d0a4c21e5427a772
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL2A1 CFH CCN4 NTRK2	5.96e-05	178	53	4	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 RNF144A PTCH1	5.96e-05	178	53	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASAP2 SPRY4 CD320 TNFRSF4	6.23e-05	180	53	4	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFH FCGBP BRINP2 MUC5B	6.36e-05	181	53	4	bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH ECM2 NTRK2 LRP1	6.50e-05	182	53	4	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	Club-club-8\|World / Class top	CFH FCGBP MUC5B MUC5AC	6.50e-05	182	53	4	8111d917e588008d947021460ddf8f1e7ae1337a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH FCGBP MUC5B MUC5AC	6.50e-05	182	53	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH CCN4 NTRK2 LRP1	6.78e-05	184	53	4	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CFHR2 THSD7A NBEAL2 CR1	6.78e-05	184	53	4	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN4 LRP1 LRRC7	6.78e-05	184	53	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	RSV-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	LRRN3 TNFRSF8 NTRK2 TNFRSF11A	6.78e-05	184	53	4	1e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCell	RSV-Healthy-5\|RSV / Virus stimulation, Condition and Cluster	LRRN3 TNFRSF8 NTRK2 TNFRSF11A	6.78e-05	184	53	4	ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP MUC5B MUC5AC MUC6	6.78e-05	184	53	4	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ECM2 NTRK2 LRP1	6.78e-05	184	53	4	fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAM23 ECM2 NTRK2	6.92e-05	185	53	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAM23 ECM2 NTRK2	6.92e-05	185	53	4	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAM23 ECM2 NTRK2	6.92e-05	185	53	4	a94694e226856bc5b168464f52d76004145717a5
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RAG1 CCN4 ECM2	6.92e-05	185	53	4	e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RAG1 CCN4 ECM2	6.92e-05	185	53	4	9d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ECM2 SPRY4 STAB1	7.07e-05	186	53	4	f23f21781a758541f59c06efa7739d26a03fb478
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ECM2 NTRK2 LRP1	7.07e-05	186	53	4	a66da8453bb78f7e9f5f59452b3c50ae679d83c3
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	CFH FCGBP MUC5B MUC5AC	7.07e-05	186	53	4	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFH FCGBP TNFRSF11A STAB1	7.07e-05	186	53	4	9673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCN4 NTRK2 LRP1	7.07e-05	186	53	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NTRK2 RNF144A LRP1	7.07e-05	186	53	4	cc94e0c5d1665d2ea2bb871ad79d8e1ec2249fb5
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL2A1 FCGBP LRP2 VWDE	7.07e-05	186	53	4	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ECM2 SPRY4 STAB1	7.07e-05	186	53	4	0de87109da9324c597fadf2eb782f0f158afe832
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFH ADAM23 NTRK2 TNFRSF4	7.22e-05	187	53	4	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	CFH SPRY4 BRINP2 MUC5B	7.22e-05	187	53	4	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH CFHR2 CCN4 ECM2	7.22e-05	187	53	4	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ASAP2 LRP2 MUC5AC	7.22e-05	187	53	4	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	FCGBP LRP1 TNFRSF11A STAB1	7.37e-05	188	53	4	d0045fdda757d191dabc7853f6a6e99c0e97d93d
Computational	Genes in the cancer module 27.	GABRE TNFRSF8 NTRK2 LRP1 LRP2 CR1 TNFRSF4	6.66e-05	355	32	7	MODULE_27
Computational	Trachea genes.	COL2A1 CFH FCGBP ECM2 LRP1 MUC5B STAB1	1.77e-04	415	32	7	MODULE_6
Drug	mono-(2-ethylhexyl)phthalate	COL2A1 FCGBP ZAN ADAM23 NBEAL2 SPRY4 MUC5B TNFRSF11A PTCH1 OTOG	2.41e-06	658	53	10	ctd:C016599
Drug	0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A	LRRN3 SCN10A LRP1 MUC5B PTCH1 MUC5AC	6.18e-06	196	53	6	3690_UP
Drug	Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A	TNFRSF8 NTRK2 SCN10A LRP2 PAX4 PTCH1	6.36e-06	197	53	6	4502_UP
Drug	Pregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A	COL2A1 GJA3 LRRN3 RASA3 SCN10A PAX4	6.55e-06	198	53	6	4218_UP
Disease	retinal detachment (is_implicated_in)	COL2A1 CFH	2.81e-06	2	50	2	DOID:5327 (is_implicated_in)
Disease	mucinous adenocarcinoma (is_marker_for)	MUC5AC MUC6	2.80e-05	5	50	2	DOID:3030 (is_marker_for)
Disease	C3 glomerulopathy	CFH CFHR2	1.01e-04	9	50	2	C4087273
Disease	pulmonary fibrosis	MUC5B MUC5AC	1.53e-04	11	50	2	EFO_0009448
Disease	Sensory hearing loss	COL2A1 LRP2	1.53e-04	11	50	2	C1691779
Disease	receptor-interacting serine/threonine-protein kinase 2 measurement	CFH ECM2	1.53e-04	11	50	2	EFO_0802997
Disease	cholangiocarcinoma (is_marker_for)	MUC5B MUC5AC MUC6	1.77e-04	64	50	3	DOID:4947 (is_marker_for)
Disease	gastric ulcer (implicated_via_orthology)	MUC5AC MUC6	2.53e-04	14	50	2	DOID:10808 (implicated_via_orthology)
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH LRP2	2.53e-04	14	50	2	DOID:10976 (biomarker_via_orthology)
Disease	Manic	THSD7A NTRK2 STAB1	3.18e-04	78	50	3	C0338831
Disease	glaucoma (is_marker_for)	CFH MUC5AC	5.24e-04	20	50	2	DOID:1686 (is_marker_for)
Disease	complement factor H-like 1 protein measurement	CFH THSD7A	6.36e-04	22	50	2	EFO_0600092
Disease	nephrosis (biomarker_via_orthology)	CFH LRP2	6.36e-04	22	50	2	DOID:2527 (biomarker_via_orthology)
Disease	pancreatic cancer (is_marker_for)	PTCH1 MUC5AC MUC6	6.79e-04	101	50	3	DOID:1793 (is_marker_for)
Disease	Sensorineural Hearing Loss (disorder)	COL2A1 LRP2	6.96e-04	23	50	2	C0018784
Disease	L lactate dehydrogenase measurement	CFH STAB1	8.91e-04	26	50	2	EFO_0004808
Disease	response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema	THSD7A VWDE	8.91e-04	26	50	2	EFO_0005325, EFO_0005532, EFO_0010735
Disease	hair shape measurement	KRTAP2-3 KRTAP2-4	9.61e-04	27	50	2	EFO_0007824
Disease	complement factor H-related protein 2 measurement	CFH CFHR2	1.11e-03	29	50	2	EFO_0600055
Disease	Child Development Disorders, Specific	NTRK2 LRP2	1.11e-03	29	50	2	C0085997
Disease	Child Development Deviations	NTRK2 LRP2	1.11e-03	29	50	2	C0085996
Disease	Developmental Disabilities	NTRK2 LRP2	1.19e-03	30	50	2	C0008073
Disease	anxiety disorder	THSD7A NTRK2	1.19e-03	30	50	2	EFO_0006788
Disease	Age related macular degeneration	CFH CFHR2	1.19e-03	30	50	2	C0242383
Disease	Complement deficiency disease	CFH CFHR2	1.44e-03	33	50	2	C0272242
Disease	COVID-19 symptoms measurement	MUC5B MUC5AC	1.62e-03	35	50	2	EFO_0600019
Disease	facial emotion recognition measurement	GJA3 THSD7A	1.62e-03	35	50	2	EFO_0008329
Disease	asthma	TNFRSF8 SPRY4 LRP1 TNFRSF11A PTCH1 MUC5AC	1.63e-03	751	50	6	MONDO_0004979

Protein segments in the cluster

Peptide	Gene	Start	Entry
WEPSSRKPKCDCTES	ADAM23	441	O75077
SNRSCADCKAPDPDW	ARAP2	696	Q8WZ64
DTSSRPQFCKWPCEC	CCN4	41	O95388
CTESGWRPLPSCEEK	CFH	251	P08603
VWKPEPCRICVCDTG	COL2A1	46	P02458
LCVSWRTPDTCPLFC	MUC5B	1141	Q9HC84
WRSSCPAKECPESLC	RAG1	896	P15918
WLCCRAPSDSAPGCS	RASA3	696	Q14644
WVCTERPCPGHCSLE	MUC6	386	Q6W4X9
PARLSGDCCTPWARC	LRRC7	496	Q96NW7
CKDSGRCIPARWKCD	LRP1	3501	Q07954
CDRKKCEWLCLLSPS	LRP1	4151	Q07954
CCDCGAPDPTWLSTN	ASAP2	436	O43150
CRTSGLCVPLTWRCD	CD320	61	Q9NPF0
PSSCTAVVCRPCCWA	KRTAP2-2	81	Q9BYT5
PSSCTAVVCRPCCWA	KRTAP2-3	81	P0C7H8
TCAEEGWSPTPKCLR	CFHR2	71	P36980
PSSCTAVVCRPCCWA	KRTAP2-1	81	Q9BYU5
GPRSLCSKLACCEWC	GABRE	436	P78334
PSSCTAVVCRPCCWA	KRTAP2-4	81	Q9BYR9
CSPREWSCPESGRCI	LRP2	266	P98164
CEAATWTLTCRPKLC	MUC5AC	5301	P98088
PCRTWCPASTCQAVC	RNF144A	106	P50876
PSCYQLCWATAPERC	PAX4	276	O43316
GWMERSSLCPTCRCP	CHFR	331	Q96EP1
WSPEAPRCAVKSCDD	CR1	1246	P17927
DPLCWDECRGSCPTC	FCGBP	3051	Q9Y6R7
WDECRGSCPTCPEDR	FCGBP	4256	Q9Y6R7
RACSEPSPWTCLLCS	FAM25E	96	A8MYX2
STCTFWPCFELCCPE	IGFL3	71	Q6UXB1
WSPEPCTTCLCSDGR	ECM2	116	O94769
SWRVVDCPESCCEPC	KRTAP10-10	16	P60014
CDRWPCPNTVDCFIS	GJA3	181	Q9Y6H8
WCTLCDRAYPSDCPE	PRDM4	376	Q9UKN5
VWSPDRCCPYKSCEC	OTOG	2631	Q6ZRI0
KCKECASPRTLPSCW	SPRY4	166	Q9C004
PCPRSCDDLVHCVWR	SSPOP	3326	A2VEC9
ACDAPCPKDCVLSTW	THSD7A	626	Q9UPZ6
KVDCPRLCTCEIRPW	LRRN3	26	Q9H3W5
RWLCDSCPASRATCV	NBEAL2	476	Q6ZNJ1
DPHCAWDPESRTCCL	SEMA4A	511	Q9H3S1
SDSSLHCLEPPCTKW	PTCH1	716	Q13635
ISCCSDHRCKWLPAS	SIAE	441	Q9HAT2
KENDCWCKCSPTFPE	BRINP2	291	Q9C0B6
CKCSASRIWCSDPSP	NTRK2	36	Q16620
ECIAPSICHCPSSWE	VWDE	1531	Q8N2E2
LLWEDTLTPNCCPVC	TRIM77	41	I1YAP6
RHCPCCKLDTTKSPW	SCN10A	1121	Q9Y5Y9
APCASCCHSRWPSLT	SERINC4	41	A6NH21
TPCAWNSSRVCECRP	TNFRSF8	96	P28908
TPCAWNSSRTCECRP	TNFRSF8	271	P28908
CWPSPCSLLAQCSVS	STAB1	236	Q9NY15
EKLECSLWCCLSDPS	UBE2Q2L	46	H0YL09
CKPCTWCNLRSGSER	TNFRSF4	81	P43489
LEEFKPSPCEWCRCE	VWC2L	126	B2RUY7
DRGRCWLCLSSPCCS	SLC35G1	41	Q2M3R5
WLCLSSPCCSRTEPE	SLC35G1	46	Q2M3R5
SCNCTEPLCRTDWTP	TNFRSF11A	401	Q9Y6Q6
LPSCSPSCWDLDGRC	ZAN	2221	Q9Y493