Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	susceptibility to T cell mediated cytotoxicity	PVR NECTIN2	3.94e-05	2	130	2	GO:0060370
GeneOntologyBiologicalProcess	cytosolic transport	TANC2 MAP2 VPS13C LRRK2 TMEM87B TMED9 KIF5A	4.68e-05	150	130	7	GO:0016482
GeneOntologyBiologicalProcess	dense core granule cytoskeletal transport	TANC2 MAP2 KIF5A	5.16e-05	12	130	3	GO:0099519
MousePheno	abnormal estrous cycle	KDM3B SCD5 GREM2 GCLM PRKAA1 C3 DDX20	2.54e-05	120	101	7	MP:0001927
MousePheno	abnormal ovulation cycle	KDM3B SCD5 GREM2 GCLM PRKAA1 C3 DDX20	3.49e-05	126	101	7	MP:0009344
Domain	Rrp44_S1	DIS3L DIS3	4.66e-05	2	128	2	PF17215
Domain	RRP44_S1	DIS3L DIS3	4.66e-05	2	128	2	IPR033770
Domain	RIBONUCLEASE_II	DIS3L DIS3	1.39e-04	3	128	2	PS01175
Domain	Rrp44_CSD1	DIS3L DIS3	1.39e-04	3	128	2	PF17216
Domain	BMP_1/tolloid-like	BMP1 TLL1	1.39e-04	3	128	2	IPR015446
Domain	Rrp44_CSD1	DIS3L DIS3	1.39e-04	3	128	2	IPR033771
Domain	ZINC_FINGER_C2H2_2	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 PRMT3 ZNF528 ZNF649 ZNF281	2.75e-04	775	128	15	PS50157
Domain	RNase_II/R_CS	DIS3L DIS3	2.77e-04	4	128	2	IPR022966
Domain	Shroom_fam	SHROOM2 SHROOM4	2.77e-04	4	128	2	IPR027685
Domain	ASD2_dom	SHROOM2 SHROOM4	2.77e-04	4	128	2	IPR014799
Domain	ASD2	SHROOM2 SHROOM4	2.77e-04	4	128	2	PF08687
Domain	ASD2	SHROOM2 SHROOM4	2.77e-04	4	128	2	PS51307
Domain	ZINC_FINGER_C2H2_1	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 PRMT3 ZNF528 ZNF649 ZNF281	2.82e-04	777	128	15	PS00028
Domain	zf-C2H2	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649 ZNF281	2.88e-04	693	128	14	PF00096
Domain	zf-C2H2_6	ZNF141 ZNF200 PRDM2 ZNF878 ZNF852 ZNF382 ZNF737 ZNF749 ZNF649	3.17e-04	314	128	9	PF13912
Domain	Znf_C2H2-like	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 PRMT3 ZNF528 ZNF649 ZNF281	3.64e-04	796	128	15	IPR015880
Domain	Znf_C2H2	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 PRMT3 ZNF528 ZNF649 ZNF281	4.10e-04	805	128	15	IPR007087
Domain	ZnF_C2H2	ZNF141 TSHZ2 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 PRMT3 ZNF528 ZNF649 ZNF281	4.26e-04	808	128	15	SM00355
Domain	Peptidase_M12A	BMP1 TLL1	6.87e-04	6	128	2	IPR001506
Domain	Astacin	BMP1 TLL1	6.87e-04	6	128	2	PF01400
Domain	-	ZNF141 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649 ZNF281	7.89e-04	679	128	13	3.30.160.60
Domain	KRAB	ZNF141 ZNF23 ZNF878 ZNF852 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649	8.14e-04	358	128	9	PS50805
Domain	Znf_C2H2/integrase_DNA-bd	ZNF141 ZNF200 PRDM2 ZNF23 ZNF878 ZNF852 MTF1 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649 ZNF281	9.64e-04	694	128	13	IPR013087
Domain	KRAB	ZNF141 ZNF23 ZNF878 ZNF852 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649	1.01e-03	369	128	9	SM00349
Domain	KRAB	ZNF141 ZNF23 ZNF878 ZNF852 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649	1.03e-03	370	128	9	IPR001909
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	WAPL HK2 KDM3B MIB2 CLSTN1 DIS3 DENND3 TSR1 ELMO2 DSTYK TLL1 PRKAA1 RACGAP1 METTL16	2.00e-07	650	132	14	38777146
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM3A WAPL DIS3L MAGEH1 VPS26C MRPS35 BIRC2 SHROOM2 CREBZF FBH1 VPS35L USP32 OSBPL1A ASTN2 ZNF528 KIF5A STAMBPL1 FHL1 WDR17	4.19e-07	1285	132	19	35914814
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	FLNA VRK1 ERCC2 WAPL MTHFD1L GARS1 KDM3B MRPS35 CCT4 DIS3 ADD2 KNOP1 TSR1 GCLM DDX23 TMED9 DDX20 PRMT3	2.67e-06	1318	132	18	30463901
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNA VRK1 WAPL HK2 MTHFD1L VPS13C GARS1 MRPS35 CCT4 DIS3 PRDM2 URB1 TSR1 RACGAP1 TMED9 DDX20 PRMT3 FHL1	7.80e-06	1425	132	18	30948266
Pubmed	Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice.	PVR NECTIN2	1.43e-05	2	132	2	25384044
Pubmed	Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional.	LDLR BMP1	1.43e-05	2	132	2	31600776
Pubmed	Skeletal muscle expression of bone morphogenetic protein-1 and tolloid-like-1 extracellular proteases in different fiber types and in response to unloading, food deprivation and differentiation.	BMP1 TLL1	1.43e-05	2	132	2	20658214
Pubmed	Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins.	LDLR PLTP	1.43e-05	2	132	2	14993244
Pubmed	Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.	BMP1 TLL1	1.43e-05	2	132	2	7798260
Pubmed	Influence of C3 deficiency on atherosclerosis.	LDLR C3	1.43e-05	2	132	2	12081998
Pubmed	Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma.	PVR NECTIN2	1.43e-05	2	132	2	37383234
Pubmed	PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity.	LDLR PLTP	1.43e-05	2	132	2	15258196
Pubmed	Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.	LDLR BMP1	1.43e-05	2	132	2	31388055
Pubmed	Abundance of follicular helper T cells in Peyer's patches is modulated by CD155.	PVR NECTIN2	1.43e-05	2	132	2	19688744
Pubmed	Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1.	BMP1 TLL1	1.43e-05	2	132	2	8661043
Pubmed	Molecular cloning and characterization of a novel nuclear protein kinase in mice.	VRK1 C3	1.43e-05	2	132	2	9521809
Pubmed	Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.	BMP1 TLL1	1.43e-05	2	132	2	28000152
Pubmed	Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development.	LDLR PLTP	1.43e-05	2	132	2	17170377
Pubmed	Acute elevation of plasma PLTP activity strongly increases pre-existing atherosclerosis.	LDLR PLTP	1.43e-05	2	132	2	18421000
Pubmed	Proteolysis of the low-density lipoprotein receptor in hepatocytes is mediated by BMP1 but not by other astacin proteases.	LDLR BMP1	1.43e-05	2	132	2	37235726
Pubmed	Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.	BMP1 TLL1	1.43e-05	2	132	2	33169406
Pubmed	Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study.	LDLR PLTP	1.43e-05	2	132	2	18711210
Pubmed	Beta-adducin and sodium-calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis.	ADD2 SLC8A1	1.43e-05	2	132	2	26045217
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	VPS13C GARS1 NEB DENND3 BMP1 DNAH11	2.63e-05	152	132	6	34299191
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A WAPL VPS13C KDM3B LRCH1 DIS3 TUBGCP6 TSR1 RACGAP1 L3MBTL3	3.63e-05	529	132	10	14621295
Pubmed	Human colostrum: identification of minor proteins in the aqueous phase by proteomics.	KLK11 SELENBP1 XDH APOH C3 PLTP	3.76e-05	162	132	6	16502470
Pubmed	Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients.	PVR NECTIN2	4.28e-05	3	132	2	21383766
Pubmed	Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice.	SCD5 LDLR	4.28e-05	3	132	2	17960025
Pubmed	Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.	BMP1 TLL1	4.28e-05	3	132	2	18824173
Pubmed	Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.	BMP1 TLL1	4.28e-05	3	132	2	12808086
Pubmed	BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.	BMP1 TLL1	4.28e-05	3	132	2	28068493
Pubmed	Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids.	APOH LDLR	4.28e-05	3	132	2	20223219
Pubmed	Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor.	PVR NECTIN2	4.28e-05	3	132	2	16249389
Pubmed	Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases.	BMP1 TLL1	4.28e-05	3	132	2	32209430
Pubmed	Bone morphogenetic protein-1 processes probiglycan.	BMP1 TLL1	4.28e-05	3	132	2	10896944
Pubmed	The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity.	PVR NECTIN2	4.28e-05	3	132	2	19815499
Pubmed	Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice.	SCD5 LDLR	4.28e-05	3	132	2	30139760
Pubmed	Immunoglobulin treatment reduces atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice via the complement system.	LDLR C3	4.28e-05	3	132	2	16297155
Pubmed	Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.	HK2 XDH	4.28e-05	3	132	2	29414774
Pubmed	Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).	PVR NECTIN2	4.28e-05	3	132	2	15536144
Pubmed	Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.	BMP1 TLL1	4.28e-05	3	132	2	24419319
Pubmed	Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.	MAP2 KIF5A	4.28e-05	3	132	2	21768290
Pubmed	Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient mice.	LDLR C3	4.28e-05	3	132	2	19729477
Pubmed	Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation.	BMP1 TLL1	4.28e-05	3	132	2	27847137
Pubmed	Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E.	LDLR PLTP	4.28e-05	3	132	2	12105225
Pubmed	Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis.	SCD5 LDLR	4.28e-05	3	132	2	19095997
Pubmed	Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice.	LDLR PRKAA1	4.28e-05	3	132	2	26822081
Pubmed	Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia.	ERCC2 ITGA2	4.28e-05	3	132	2	29121049
Pubmed	Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands.	PVR NECTIN2	4.28e-05	3	132	2	15752754
Pubmed	Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.	BMP1 TLL1	4.28e-05	3	132	2	19079247
Pubmed	Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).	PVR NECTIN2	4.28e-05	3	132	2	15039383
Pubmed	PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.	PVR NECTIN2	4.28e-05	3	132	2	15607800
Pubmed	Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites.	SCD5 LDLR	4.28e-05	3	132	2	38354249
Pubmed	Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency.	LDLR PLTP	4.28e-05	3	132	2	11433351
Pubmed	Atherogenic, enlarged, and dysfunctional HDL in human PLTP/apoA-I double transgenic mice.	LDLR PLTP	4.28e-05	3	132	2	17761633
Pubmed	Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency.	LDLR PLTP	4.28e-05	3	132	2	17928634
Pubmed	Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase.	BMP1 TLL1	4.28e-05	3	132	2	20043912
Pubmed	Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo.	LDLR PRKAA1	4.28e-05	3	132	2	20124121
Pubmed	Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains.	BMP1 TLL1	4.28e-05	3	132	2	16507574
Pubmed	Transforming growth factor-β-activated kinase 1 regulates angiogenesis via AMP-activated protein kinase-α1 and redox balance in endothelial cells.	LDLR PRKAA1	4.28e-05	3	132	2	24072697
Pubmed	The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation.	PVR NECTIN2	4.28e-05	3	132	2	26840537
Pubmed	Linkage disequilibrium analysis of two genes mapping on OFC3: PVR and PVRL2.	PVR NECTIN2	4.28e-05	3	132	2	17534374
Pubmed	The involvement of beta2-glycoprotein I (beta2-GPI) in human and murine atherosclerosis.	APOH LDLR	4.28e-05	3	132	2	10441168
Pubmed	Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).	PVR NECTIN2	4.28e-05	3	132	2	28515320
Pubmed	Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.	PVR NECTIN2	4.28e-05	3	132	2	12913096
Pubmed	DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis.	PVR NECTIN2	4.28e-05	3	132	2	34504191
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	KDM3B AGGF1 ITGA2 DENND3 PRDM2 SHROOM4 DSTYK PVR NOL8 DNAH11	5.18e-05	552	132	10	10737800
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FLNA WAPL HK2 CLSTN1 URB1 PVR NECTIN2 EIF2B2 TMED9 DDX20 METTL16 COG5 ZNF281	6.45e-05	942	132	13	31073040
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNA WAPL SCD5 SHROOM2 LDLR DIS3 PRDM2 KNOP1 URB1 SLC7A3 TSR1 PRKAA1 VPS35L COG5	6.78e-05	1084	132	14	11544199
Pubmed	Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.	KDM3A KDM3B	8.54e-05	4	132	2	29526734
Pubmed	Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.	KDM3A KDM3B	8.54e-05	4	132	2	23593242
Pubmed	Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice.	LDLR C3	8.54e-05	4	132	2	15059809
Pubmed	The role of the small intestine in modulating metabolism and inflammation in atherosclerosis and cancer.	SCD5 LDLR	8.54e-05	4	132	2	31356236
Pubmed	Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.	SHROOM2 SHROOM4	8.54e-05	4	132	2	16684770
Pubmed	The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.	BMP1 TLL1	8.54e-05	4	132	2	10331975
Pubmed	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.	PVR NECTIN2	8.54e-05	4	132	2	19011627
Pubmed	BMP1-like proteinases are essential to the structure and wound healing of skin.	BMP1 TLL1	8.54e-05	4	132	2	27363389
Pubmed	The P2Y2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells.	FLNA LDLR	8.54e-05	4	132	2	27522265
Pubmed	Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.	HYDIN DNAH11	8.54e-05	4	132	2	36140829
Pubmed	AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.	LDLR PRKAA1	8.54e-05	4	132	2	21459323
Pubmed	Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration.	LDLR NECTIN2	8.54e-05	4	132	2	28062492
Pubmed	Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.	PVR NECTIN2	8.54e-05	4	132	2	16304049
Pubmed	Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP.	LRRK2 PRKAA1	8.54e-05	4	132	2	22012985
Pubmed	Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.	LDLR C3	8.54e-05	4	132	2	37499656
Pubmed	JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.	KDM3A KDM3B	8.54e-05	4	132	2	16603237
Pubmed	Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.	MTHFD1L NECTIN2	8.54e-05	4	132	2	20885792
Pubmed	Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition.	PVR NECTIN2	8.54e-05	4	132	2	38592213
Pubmed	Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains.	PVR NECTIN2	8.54e-05	4	132	2	12759359
Pubmed	Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.	FLNA NEB	8.54e-05	4	132	2	16902413
Pubmed	A new standard nomenclature for proteins related to Apx and Shroom.	SHROOM2 SHROOM4	8.54e-05	4	132	2	16615870
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KDM3A VRK1 WAPL KDM3B PRDM2 KNOP1 TSR1 RACGAP1 ZNF649 ZNF281	1.15e-04	608	132	10	36089195
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 DIS3L CLSTN1 DENND3 SHROOM4 PER3 DSTYK ASTN2 N4BP1	1.17e-04	493	132	9	15368895
Pubmed	Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.	SCD5 LDLR BMP1 PRKAA1	1.26e-04	67	132	4	16806233
Pubmed	NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47.	URB1 NOL8	1.42e-04	5	132	2	16963496
Pubmed	Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process.	PVR NECTIN2	1.42e-04	5	132	2	16831868
Pubmed	Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cells.	DIS3L DIS3	1.42e-04	5	132	2	20368444
Pubmed	PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1.	BMP1 TLL1	1.42e-04	5	132	2	12393877
Pubmed	Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study.	DGKI DNAH11	1.42e-04	5	132	2	24468470
Pubmed	Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domain.	PVR NECTIN2	1.42e-04	5	132	2	12011057
Pubmed	Curcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H).	CREBZF PRKAA1	1.42e-04	5	132	2	21994947
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF141 TSHZ2 ZNF200 ZNF23 ZNF878 ZNF852 ZNF382 ZNF737 ZNF749 ZNF528 ZNF649 ZNF281	2.02e-04	718	89	12	28
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP1 TLL1	3.55e-04	6	89	2	894
GeneFamily	Exosome complex	DIS3L DIS3	1.53e-03	12	89	2	817
GeneFamily	Chaperonins	CCT4 BBS12	2.41e-03	15	89	2	587
Coexpression	MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN	MRPS35 BIRC2 CCT4 DIS3 FZD1 LRRC42 VPS35L C8orf76 DDX20 ZNF281	1.18e-06	272	131	10	M15123
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TANC2 MTHFD1L LRRK2 SLC26A9 ITGA2 LDLR HPCAL1 C3	8.73e-08	186	132	8	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	(09)_Ionocytes-(3)_72hpi\|(09)_Ionocytes / shred by cell type and Timepoint	FLNA DIS3L GARS1 AGGF1 ELMO2 L3MBTL3	9.49e-07	110	132	6	fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37\|World / Primary Cells by Cluster	MAP2 TSHZ2 MAGEH1 SCD5 CLSTN1 SYNPR CRYM	2.06e-06	197	132	7	00d756bc0231e1b3b88430214338c1059cb11106
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MTHFD1L FAM153B DGKI CNTN3 ASTN2 FYB2	8.33e-06	160	132	6	9049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MTHFD1L FAM153B DGKI CNTN3 ASTN2 FYB2	8.33e-06	160	132	6	f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MTHFD1L FAM153B DGKI CNTN3 ASTN2 FYB2	8.33e-06	160	132	6	0eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA LRRK2 XDH LDLR C3 PLTP	8.33e-06	160	132	6	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 LRRK2 APOH LDLR HPCAL1 C3	9.59e-06	164	132	6	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 LRRK2 APOH LDLR HPCAL1 C3	9.59e-06	164	132	6	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 SYNPR CFAP65 PPP1R1A HYDIN FYB2	1.03e-05	166	132	6	d96c562e1483adb4cdd817b68133f03356d7279b
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C LRRK2 SCD5 TBC1D8B FZD1 DNAH11	1.10e-05	168	132	6	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 LRRK2 ITGA2 LDLR BMP1 C3	1.58e-05	179	132	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 LRRK2 VPS41 ASTN2 HYDIN DNAH11	1.68e-05	181	132	6	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MTHFD1L ITGA2 LDLR SHROOM4 GCLM C3	1.68e-05	181	132	6	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 PAPPA2 MAP2 LRRK2 ASTN2 STAMBPL1	1.84e-05	184	132	6	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR31 CFAP65 C3 BBS12 HYDIN DNAH11	1.84e-05	184	132	6	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL12RB2 TSHZ2 CRYM TLL1 CNTN3 STAMBPL1	1.84e-05	184	132	6	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR31 CFAP65 C3 BBS12 HYDIN DNAH11	1.84e-05	184	132	6	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR31 CFAP65 C3 BBS12 HYDIN DNAH11	1.84e-05	184	132	6	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	SELENBP1 LRRK2 TDRD1 BMP1 CRYM C3	1.90e-05	185	132	6	3b3268e3f99121124e33086cac88479808d31630
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSHZ2 LRRK2 ITGA2 VSIG10 PCDH12 TUBGCP6	1.90e-05	185	132	6	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 GCNT3 CLCA3P PER3 HPCAL1 FHL1	1.96e-05	186	132	6	32d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	PCDH12 NEB FZD1 PER3 OSBPL1A PLTP	2.02e-05	187	132	6	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 LRRK2 ITGA2 LDLR BMP1 C3	2.08e-05	188	132	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SELENBP1 LRRK2 SLC26A9 SHROOM4 BMP1 C3	2.14e-05	189	132	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 MAP2 SCD5 DENND3 HPCAL1 FHL1	2.27e-05	191	132	6	a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCell	IPF-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	KLK11 LDLR PPP1R1A CRYM TLL1 C3	2.27e-05	191	132	6	267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR BMP1	2.41e-05	193	132	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	MTHFD1L SCD5 PARP14 SHROOM2 SHROOM4 TLL1	2.41e-05	193	132	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 LDLR BMP1 C3	2.41e-05	193	132	6	8646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSHZ2 ITGA2 CFAP65 HYDIN FYB2 DNAH11	2.41e-05	193	132	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	TANC2 SELENBP1 LRRK2 SLC26A9 BMP1 C3	2.41e-05	193	132	6	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR BMP1	2.41e-05	193	132	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	COPD-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	KLK11 GCNT3 TSHZ2 PPP1R1A CRYM TLL1	2.48e-05	194	132	6	72a2e0cba171ab59aa176e91a59a54c562af0390
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR BMP1	2.48e-05	194	132	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PCDH12 FZD1 PER3 OSBPL1A C3 PLTP	2.55e-05	195	132	6	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 APOH LDLR BMP1	2.55e-05	195	132	6	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 APOH LDLR BMP1	2.55e-05	195	132	6	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.55e-05	195	132	6	460e12044905370797fd9774e99c3aedaebfe343
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 APOH LDLR BMP1	2.55e-05	195	132	6	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.55e-05	195	132	6	ff9f6b38f41dc5660b746fe40ceaddfb2958acd3
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.63e-05	196	132	6	1ff4b41817556a6e573f0737819a5cc24a7ef821
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 APOH BMP1 C3	2.63e-05	196	132	6	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	SELENBP1 LRRK2 SLC26A9 LDLR BMP1 C3	2.63e-05	196	132	6	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.63e-05	196	132	6	020110cd79453df9546fb20802fe38ecadd9fe74
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.63e-05	196	132	6	8e909c31733762646359fe78b645cbd60237459e
ToppCell	Bronchial_Biopsy-Epithelial-Club\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	KLK11 HK2 SELENBP1 PPP1R1A CRYM C3	2.63e-05	196	132	6	057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 SLC26A9 LDLR BMP1 C3	2.63e-05	196	132	6	65e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR C3	2.70e-05	197	132	6	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.70e-05	197	132	6	ff19e4c45715752a04541ad6a0cdf5454c9daaa2
ToppCell	Bronchial_Biopsy-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	KLK11 HK2 SELENBP1 PPP1R1A CRYM C3	2.70e-05	197	132	6	3f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP2 ITGA2 SCD5 DENND3 FHL1 FYB2	2.70e-05	197	132	6	69d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 LRRK2 APOH LDLR BMP1 C3	2.70e-05	197	132	6	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	tumor_Lung-Epithelial_cells-tS1\|tumor_Lung / Location, Cell class and cell subclass	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR CRYM	2.70e-05	197	132	6	8336e6647604e4bdd1596ea554c22203d13782e9
ToppCell	AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SELENBP1 LRRK2 SLC26A9 ITGA2 CRYM C3	2.70e-05	197	132	6	8b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCell	LAM-Epithelial-AT2\|Epithelial / Condition, Lineage and Cell class	TANC2 SELENBP1 LRRK2 APOH BMP1 C3	2.70e-05	197	132	6	27e6eb7bbc27e7635df1aae7c7d75f8a3f1b1cc2
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TANC2 SELENBP1 LRRK2 SLC26A9 LDLR C3	2.70e-05	197	132	6	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP2 ITGA2 SCD5 DENND3 FHL1 FYB2	2.70e-05	197	132	6	e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELENBP1 LRRK2 SLC26A9 APOH LDLR C3	2.78e-05	198	132	6	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TANC2 LRRK2 ITGA2 LDLR BMP1 C3	2.78e-05	198	132	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Biopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KLK11 SELENBP1 XDH SCD5 PPP1R1A CRYM	2.78e-05	198	132	6	a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.78e-05	198	132	6	778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 SELENBP1 PPP1R1A CRYM C3 FYB2	2.78e-05	198	132	6	7896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCell	distal-Epithelial-Mucous-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK11 GCNT3 SCD5 PPP1R1A CRYM C3	2.86e-05	199	132	6	35fb7bd35e53d8ca189fe8c7744211a5201081f6
ToppCell	proximal-Epithelial-Mucous-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK11 GCNT3 PPP1R1A URB1 CRYM C3	2.86e-05	199	132	6	baac580484124b7c36717b607adcf2cb446e631d
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TSHZ2 ITGA2 PCDH12 SHROOM2 SHROOM4 NECTIN2	2.86e-05	199	132	6	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	proximal-Epithelial-Mucous\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK11 GCNT3 PPP1R1A URB1 CRYM C3	2.86e-05	199	132	6	15ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCell	Biopsy_Other_PF-Epithelial-SCGB3A2+_SCGB1A1+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	KLK11 SELENBP1 XDH SCD5 CRYM C3	2.86e-05	199	132	6	036244251d2dd39f8184b7095418c723c0524eff
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TANC2 LRRK2 SCD5 LDLR CNTN3 HYDIN	2.86e-05	199	132	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	SELENBP1 LRRK2 SLC26A9 LDLR BMP1 C3	2.86e-05	199	132	6	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	proximal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK11 GCNT3 PPP1R1A URB1 CRYM C3	2.86e-05	199	132	6	3018378860de084662be0cc46fce421db3bb9ec9
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 LRRK2 LDLR BMP1 CRYM C3	2.94e-05	200	132	6	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 LRRK2 LDLR BMP1 CRYM C3	2.94e-05	200	132	6	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SELENBP1 LRRK2 LDLR BMP1 CRYM C3	2.94e-05	200	132	6	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP2 LRRK2 SLC8A1 TLL1 DGKI CNTN3	2.94e-05	200	132	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Influenza_Severe-CD4+_T_naive\|World / Disease group and Cell class	TSHZ2 WDR31 GREM2 SHROOM4 FAM153B	8.21e-05	149	132	5	ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRK2 PARP14 GREM2 N4BP1	8.53e-05	78	132	4	d5e2e2e04e380b265b2530e93cba6f98ad329e4f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SYNPR FZD1 SLC7A3 HPCAL1 L3MBTL3	9.89e-05	155	132	5	99e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	HK2 GARS1 TBC1D8B LDLR NECTIN2	1.12e-04	159	132	5	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYM TLL1 CNTN3 WDR17 HYDIN	1.15e-04	160	132	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GCNT3 SELENBP1 CFAP65 CLCA3P DNAH11	1.15e-04	160	132	5	028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GCNT3 SELENBP1 CFAP65 CLCA3P DNAH11	1.15e-04	160	132	5	1f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYM TLL1 CNTN3 WDR17 HYDIN	1.15e-04	160	132	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	KLK11 CRYM TLL1 CNTN3 FYB2	1.40e-04	167	132	5	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	WAPL TSHZ2 FAM117B ELMO2 KIF5A	1.40e-04	167	132	5	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	TSHZ2 SCD5 NEB C3 BBS12	1.48e-04	169	132	5	dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ITGA2 SCD5 GREM2 ZNF23 STAMBPL1	1.48e-04	169	132	5	1d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ITGA2 SCD5 GREM2 ZNF23 STAMBPL1	1.48e-04	169	132	5	58098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK2 NEB VPS35L STAMBPL1 NOL8	1.48e-04	169	132	5	813472d429c0b12580b17b440e00a6d8beb7947f
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TSHZ2 TLL1 ASTN2 FHL1 PLTP	1.52e-04	170	132	5	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	MAP2 SCD5 LDLR HPCAL1 FYB2	1.52e-04	170	132	5	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	TSHZ2 GARS1 PCDH12 TLL1 VPS35L	1.57e-04	171	132	5	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KDM3A FLNA HK2 PCDH12 HPCAL1	1.61e-04	172	132	5	965a9f62b73a7e3531c343121a7c507b7e1bfe05
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KLK11 FAM153B TLL1 DGKI GSDMA	1.65e-04	173	132	5	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL12RB2 TSHZ2 CRYM TLL1 CNTN3	1.65e-04	173	132	5	ee972d9cc68755926512fd3bbe1267098c67cd94
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	SCD5 DENND3 BMP1 MTF1 ELMO2 DSTYK ASTN2 ZNF749 CLBA1	2.11e-06	195	132	9	3669_DN
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A	TANC2 PAPPA2 MAGEH1 SCD5 NEB BMP1 DSTYK N4BP1 METTL16	2.20e-06	196	132	9	3726_DN
Drug	Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A	PAPPA2 AGGF1 BMP1 PER3 PVR NECTIN2 METTL16 FHL1 CLBA1	2.30e-06	197	132	9	2743_UP
Drug	Dimethadione [695-53-4]; Down 200; 31uM; PC3; HT_HG-U133A	SHROOM2 TBC1D8B LDLR DIS3 DENND3 BMP1 ELMO2 DSTYK	1.87e-05	195	132	8	4607_DN
Drug	Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A	ERCC2 APOH BMP1 PVR KIF5A METTL16 FHL1 CLBA1	1.94e-05	196	132	8	3372_UP
Drug	Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A	MAP2 PCDH12 SCD5 NEB LDLR DIS3 C3 N4BP1	1.94e-05	196	132	8	2236_UP
Drug	dimyristoylphosphatidylglycerol	FLNA APOH LDLR CREBZF	1.98e-05	28	132	4	CID000107767
Drug	SC 19220; Down 200; 10uM; PC3; HT_HG-U133A	ERCC2 AGGF1 ZNF200 KNOP1 DSTYK PRKAA1 VPS35L FHL1	2.08e-05	198	132	8	7095_DN
Drug	Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; PC3; HT_HG-U133A	GCNT3 TBC1D8B ADD2 FZD1 BMP1 PVR ASTN2 ZNF528	2.08e-05	198	132	8	5096_UP
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SCD5 TDRD1 CREBZF FZD1 PER3 PVR N4BP1 FHL1	2.08e-05	198	132	8	5431_DN
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; HL60; HT_HG-U133A	ERCC2 VSIG10 NEB LRCH1 DSTYK N4BP1 ZNF528 PLTP	2.08e-05	198	132	8	2182_DN
Disease	Dyslipidemias	LDLR NECTIN2 PLTP DNAH11	2.96e-06	24	124	4	C0242339
Disease	Dyslipoproteinemias	LDLR NECTIN2 PLTP DNAH11	2.96e-06	24	124	4	C0598784
Disease	OROFACIAL CLEFT 1	PVR NECTIN2	1.75e-05	2	124	2	C1861537
Disease	Intellectual Disability	TANC2 VRK1 KDM3B PCDH12 METTL23 SHROOM4 MTF1 KLHL15 PCYT2 KIF5A	2.02e-05	447	124	10	C3714756
Disease	phospholipids in IDL measurement	APOH LDLR NECTIN2 PLTP	6.88e-05	52	124	4	EFO_0022164
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	APOH LDLR PLTP	9.12e-05	21	124	3	EFO_0022246
Disease	free cholesterol to total lipids in medium VLDL percentage	APOH LDLR NECTIN2 PLTP	9.88e-05	57	124	4	EFO_0022284
Disease	free cholesterol to total lipids in very large VLDL percentage	APOH LDLR NECTIN2 PLTP	1.13e-04	59	124	4	EFO_0022289
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	FAM117B LDLR NECTIN2 PLTP DNAH11	1.57e-04	120	124	5	EFO_0004611, EFO_0004639
Disease	asphyxia neonatorum (biomarker_via_orthology)	ERCC2 MAP2	2.60e-04	6	124	2	DOID:11088 (biomarker_via_orthology)
Disease	Osteochondritis dissecans	SCD5 SLC8A1	3.63e-04	7	124	2	HP_0010886
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	APOH LDLR PLTP	3.94e-04	34	124	3	EFO_0008317, EFO_0008596, EFO_0020944
Disease	apolipoprotein B measurement	ERCC2 FAM117B APOH LDLR PVR NECTIN2 L3MBTL3 HYDIN PLTP DNAH11	5.04e-04	663	124	10	EFO_0004615
Disease	triglycerides to total lipids in large VLDL percentage	APOH LDLR PLTP	5.93e-04	39	124	3	EFO_0022332
Disease	Malignant neoplasm of breast	KDM3A FLNA BIRC2 XDH SHROOM2 BMP1 PER3 TLL1 PRKAA1 NECTIN2 ASTN2 ZNF281 L3MBTL3	6.01e-04	1074	124	13	C0006142
Disease	spinal muscular atrophy (implicated_via_orthology)	GARS1 KIF5A	6.19e-04	9	124	2	DOID:12377 (implicated_via_orthology)
Disease	cholesterol in very small VLDL measurement	APOH LDLR PLTP	6.39e-04	40	124	3	EFO_0022231
Disease	free cholesterol in medium LDL measurement	LDLR NECTIN2 PLTP	6.39e-04	40	124	3	EFO_0022268
Disease	theophylline measurement	LRRK2 ITGA2	7.71e-04	10	124	2	EFO_0021180
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	APOH LDLR PLTP	9.64e-04	46	124	3	EFO_0008317, EFO_0008596, EFO_0020943
Disease	oncostatin-M measurement	GSDMA C3	1.12e-03	12	124	2	EFO_0010792
Disease	phospholipids in medium LDL measurement	LDLR NECTIN2 PLTP	1.16e-03	49	124	3	EFO_0022183
Disease	cholesterol in medium LDL measurement	LDLR NECTIN2 PLTP	1.16e-03	49	124	3	EFO_0022224
Disease	cholesterol in small LDL measurement	LDLR NECTIN2 PLTP	1.16e-03	49	124	3	EFO_0022227
Disease	cholesterol to total lipids in small VLDL percentage	APOH LDLR NECTIN2	1.30e-03	51	124	3	EFO_0022242
Disease	total lipids in medium LDL	LDLR NECTIN2 PLTP	1.38e-03	52	124	3	EFO_0022180
Disease	total lipids in LDL measurement	LDLR NECTIN2 PLTP	1.38e-03	52	124	3	EFO_0022308
Disease	triglycerides to total lipids in very large VLDL percentage	APOH LDLR NECTIN2	1.46e-03	53	124	3	EFO_0022340
Disease	cholesterol in small VLDL measurement	LDLR NECTIN2 PLTP	1.46e-03	53	124	3	EFO_0022228
Disease	cholesteryl esters to total lipids in very large VLDL percentage	APOH LDLR NECTIN2	1.46e-03	53	124	3	EFO_0022258
Disease	cholesterol to total lipids in very large VLDL percentage	APOH LDLR NECTIN2	1.54e-03	54	124	3	EFO_0022244
Disease	GDH/6PGL endoplasmic bifunctional protein measurement	APOH OVCH1	1.54e-03	14	124	2	EFO_0801619
Disease	cholesterol to total lipids in large LDL percentage	LDLR NECTIN2 PLTP	1.71e-03	56	124	3	EFO_0022235
Disease	free cholesterol to total lipids in large HDL percentage	LDLR NECTIN2 PLTP	1.71e-03	56	124	3	EFO_0022279
Disease	cholesteryl esters to total lipids in large VLDL percentage	APOH LDLR PLTP	1.71e-03	56	124	3	EFO_0022250
Disease	quinate measurement	LRRK2 ITGA2	1.77e-03	15	124	2	EFO_0021167
Disease	triglycerides to total lipids in chylomicrons and extremely large VLDL percentage	APOH PLTP	1.77e-03	15	124	2	EFO_0022328
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	APOH LDLR NECTIN2 L3MBTL3 PLTP DNAH11	1.81e-03	303	124	6	EFO_0004612, EFO_0020945
Disease	urate measurement, spine bone mineral density	PAPPA2 XDH SLC8A1	1.89e-03	58	124	3	EFO_0004531, EFO_0007701
Disease	low density lipoprotein particle size measurement	APOH LDLR PLTP	1.89e-03	58	124	3	EFO_0008593
Disease	triglycerides to total lipids in small VLDL percentage	APOH LDLR NECTIN2	1.89e-03	58	124	3	EFO_0022338
Disease	phospholipids in LDL measurement	LDLR NECTIN2 PLTP	1.89e-03	58	124	3	EFO_0022294
Disease	N-acetyl-beta-alanine measurement	KNOP1 VPS35L	2.02e-03	16	124	2	EFO_0021430
Disease	total lipids in IDL	APOH LDLR NECTIN2	2.08e-03	60	124	3	EFO_0022161
Disease	Insulin Resistance	PRKAA1 C3 PLTP	2.08e-03	60	124	3	C0021655
Disease	Insulin Sensitivity	PRKAA1 C3 PLTP	2.08e-03	60	124	3	C0920563
Disease	free cholesterol in IDL measurement	APOH LDLR NECTIN2	2.18e-03	61	124	3	EFO_0022181
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	APOH LDLR PLTP	2.18e-03	61	124	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	APOH LDLR L3MBTL3 PLTP DNAH11	2.19e-03	215	124	5	EFO_0008317, EFO_0008591
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOH PLTP	2.29e-03	17	124	2	EFO_0022232
Disease	spinal stenosis	MRPS35 ASTN2	2.29e-03	17	124	2	EFO_0007490
Disease	free cholesterol in very large HDL measurement	LDLR NECTIN2 PLTP	2.29e-03	62	124	3	EFO_0022273
Disease	triglycerides to total lipids in medium VLDL percentage	APOH LDLR NECTIN2	2.39e-03	63	124	3	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	APOH LDLR NECTIN2	2.39e-03	63	124	3	EFO_0022239
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	APOH LDLR L3MBTL3 PLTP DNAH11	2.42e-03	220	124	5	EFO_0004529, EFO_0008317
Disease	cholesteryl esters to total lipids in medium VLDL percentage	APOH LDLR NECTIN2	2.50e-03	64	124	3	EFO_0022253
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	APOH LDLR NECTIN2 L3MBTL3 PLTP	2.61e-03	224	124	5	EFO_0004574, EFO_0008317
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	GARS1 APOH LDLR NECTIN2 PLTP	2.66e-03	225	124	5	EFO_0008317, EFO_0020947
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	APOH LDLR NECTIN2 PLTP	2.71e-03	137	124	4	EFO_0004611, EFO_0008591
Disease	low density lipoprotein cholesterol measurement, physical activity	LDLR NECTIN2 DNAH11	2.73e-03	66	124	3	EFO_0003940, EFO_0004611
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	APOH LDLR L3MBTL3 PLTP DNAH11	2.87e-03	229	124	5	EFO_0004639, EFO_0008317
Disease	Stuttering	MAP2 GRIK4 DENND3 TMEM87B	3.17e-03	143	124	4	HP_0025268
Disease	non-high density lipoprotein cholesterol measurement	APOH LDLR DSTYK ZNF737 COG5 L3MBTL3 HYDIN PLTP DNAH11	3.22e-03	713	124	9	EFO_0005689
Disease	free cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOH PLTP	3.49e-03	21	124	2	EFO_0022277
Disease	free cholesterol to total lipids in large LDL percentage	LDLR NECTIN2 PLTP	3.78e-03	74	124	3	EFO_0022280
Disease	free cholesterol to total lipids in small VLDL percentage	APOH LDLR NECTIN2	3.92e-03	75	124	3	EFO_0022287

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHQVTFEVPTCEGKE	SYNPR	51	Q8TBG9
VHEKDYIPVKGEVCI	TDRD1	306	Q9BXT4
HPSVICTDDKGVFAT	ADAL	286	Q6DHV7
IDGTIEVPKCFKEHS	APOH	316	P02749
DVCLPKATHQKEFDT	ANKRD30B	741	Q9BXX2
HKEAVTIPKGCVLAF	GSDMA	191	Q96QA5
FPDVLECTVSHAVEK	GCLM	66	P48507
DKKGICVADPFEVTV	C3	811	P01024
FIEETKGIEPVHKDS	DNAH11	3026	Q96DT5
KTKCDPYVLEHGDEV	AGGF1	491	Q8N302
VTVTKEGEICGFKIH	CLSTN1	76	O94985
HSECGIIEKATSPKE	DDX20	521	Q9UHI6
ALLKPCKDFEVDSHI	DENND3	131	A2RUS2
LHGKFCGSEKPEVIT	BMP1	661	P13497
GPLKSSKFIIDEECH	BBS12	31	Q6ZW61
HECFVSPVAKAVIEL	MTHFD1L	196	Q6UB35
GSELTCIIHFPSKKV	ASTN2	911	O75129
IKGVKPAHCEKTTVF	CRYM	276	Q14894
GEPCEVGQSHKDVDK	PCDH12	786	Q9NPG4
PGCEEHGKVFKDEQI	L3MBTL3	721	Q96JM7
IKDEVHPEVKCVGSV	C8orf76	326	Q96K31
HSIFGDPKKIVTEEF	MAGEH1	126	Q9H213
VSIKHKCPEDQDAEG	CFAP65	346	Q6ZU64
DACKRGDVTVKPSHV	IL12RB2	26	Q99665
HETVKDLAPKCDVSF	HK2	876	P52789
TTHTPGCVFLEVDEK	PER3	276	P56645
KVDLVCHGKTEIIPD	PCYT2	301	Q99447
HAEFPGCKIRVTSKA	PLTP	16	P55058
KDCPTGHLTVDEFKK	HPCAL1	36	P37235
SCIKVAEDFVSPEHV	KDM3B	1696	Q7LBC6
ETRIIKGFECKPHSQ	KLK11	51	Q9UBX7
IKEDSCHRLSPVKGE	LRCH1	361	Q9Y2L9
KCGLKVISSIVHFPD	LRRK2	561	Q5S007
QHKRVPCGKEEVSLF	METTL16	356	Q86W50
VTPLRFGKDVDGKCH	ERCC2	121	P18074
KKGVSTLCEEHVEPE	KNOP1	71	Q1ED39
KCVHIPLESFDADKE	METTL23	151	Q86XA0
ISKEVEDCVPVFLKH	TUBGCP6	576	Q96RT7
VPLKEFDHSNCKTEG	LRRC42	291	Q9Y546
EDKPTHIIFGSDSEC	NOL8	791	Q76FK4
HILEVIDKCGYKEPT	DDX23	401	Q9BUQ8
IKCFDDTIHGFRVPK	OSBPL1A	301	Q9BXW6
IPRHVKKEEESFQSC	GREM2	106	Q9H772
ETAKVFSIPFHKDCG	ITGA2	776	P17301
VKLPEAFERCASKDH	DSTYK	846	Q6XUX3
DSVCVKSVHTDKPGA	PARP14	736	Q460N5
KESVHLGPLDTFCDI	PAPPA2	991	Q9BXP8
AKKRDPVSHICFIEE	COG5	356	Q9UP83
PVSHICFIEEIVKDG	COG5	361	Q9UP83
VECRKPIGADSKEVH	FHL1	41	Q13642
DTLKCEKFPVHGAGE	FZD1	211	Q9UP38
DTVHVLDDFVKVPCA	FBH1	881	Q8NFZ0
AFTCLTEKGFIHPEK	HYDIN	4026	Q4G0P3
VTYHPTEVGKESLCK	HYDIN	4591	Q4G0P3
KQVCVFDPSKEGTIE	KLHL15	441	Q96M94
SCIKVAEDFVSPEHV	KDM3A	1256	Q9Y4C1
KHECPFGRSAIELTK	ELMO2	401	Q96JJ3
PHIFKDKVVLDVGCG	PRMT3	251	O60678
SKHVKVVCDGTDLTP	DGKI	581	O75912
PVHDVTDASKVKCSG	FLNA	1441	P21333
SHLVFSIDPKGCEDV	DIS3L	471	Q8TF46
RVKVFEECSPKQLHE	FAM117B	476	Q6P1L5
EKESECEVAPKQLHS	CENPJ	646	Q9HC77
CVHVDEKSPETFKEA	GCNT3	161	O95395
VHEDKNRVPFVKGCT	KIF5A	156	Q12840
PFTEGDILEKVSVHC	EIF2B2	296	P49770
IISNICGEKEVPHFK	GRIK4	106	Q16099
CGEKEVPHFKVAPEE	GRIK4	111	Q16099
IFPVGSEDKKITLHC	CNTN3	36	Q9P232
EVAKDKAGPSIVICF	SLC7A3	56	Q8WY07
PSVVKDCIHAVLKEE	DYNLT2B	41	Q8WW35
ADGKVTVTPHSKCKV	KIF28P	436	B7ZC32
VKKRVCFPSEDHLEE	FAM153B	146	P0C7A2
EGKEFKESHSVQPTC	PRDM2	861	Q13029
IDVVLTAEGEKFPCH	KBTBD12	31	Q3ZCT8
PFQHGDKVKCLLDTD	MIB2	256	Q96AX9
CKVEHESFEKPQLLT	PVR	221	P15151
EKCEKHFPIEIDSTD	MRPS35	141	P82673
SKLHGKFCGAEVPEV	TLL1	686	O43897
FEDGSLECKHVFPSI	SLC26A9	716	Q7LBE3
VRVHTKEKPFECDVQ	MTF1	191	Q14872
CAPEKHIIKLTFEDF	OVCH1	451	Q7RTY7
HVFKVDACEGTPEKI	FYB2	406	Q5VWT5
EPVLKTSGHVDKFAD	GARS1	186	P41250
EVEAIVKGVCKPSEF	SHROOM2	1471	Q13796
HCEPLTVSKIEDGGK	SHROOM4	31	Q9ULL8
EGEKTKFLCDPRSGH	TANC2	776	Q9HCD6
EDIEFICKTIGTKPV	CCT4	331	P50991
VIEPKDIHAKCELAF	SELENBP1	121	Q13228
TDAGKIPFCDAKEEI	SCD5	6	Q86SK9
GHVETIFDCKFKPDD	WDR17	391	Q8IZU2
LHDFVSKTVIKPESC	RACGAP1	286	Q9H0H5
KEKAIEEGIPAFTCE	DIS3	181	Q9Y2L1
KEFIPCIFSSGIKED	URB1	221	O60287
DKEVSVVFIPCGHLV	BIRC2	576	Q13490
DDDHVPTLFKKICDG	PRKAA1	226	Q13131
DHFLISPKGVSCSEV	ADD2	166	P35612
SSEEKPGVERVHKLC	CLBA1	176	Q96F83
VTEFCTEKTHNKEAP	CLCA3P	246	Q9Y6N3
HIGETEKKCFIEEIP	TMED9	41	Q9BVK6
KFVIPSEVKSECHQD	UHRF1BP1L	581	A0JNW5
EPVKAKEELIFHCGF	TSR1	606	Q2NL82
HGAKDEEVPSKQCVS	ZNF749	51	O43361
SLEVGEEKHPVHLCK	TSPY1	186	Q01534
IKECDESGFPKHLLF	VPS35L	451	Q7Z3J2
FRLPKGESLKEVHEC	TBC1D8B	291	Q0IIM8
AIVCSPKHKDTGIFR	STAMBPL1	376	Q96FJ0
GVCLHVDKDKVSVEF	CREBZF	326	Q9NS37
HVVVEDTVVSDKCFP	WAPL	121	Q7Z5K2
AEIKSCHDKSGIPDE	ZNF281	591	Q9Y2X9
IDTSEAKKVPGFVCF	XDH	621	P47989
CFDFTDSKGEPLHII	VPS13C	1481	Q709C8
VKECGKESPHEEASS	TSHZ2	611	Q9NRE2
GEEFHETFDCPIKII	VPS41	116	P49754
DPKRCHDGTIEFTSI	VRK1	216	Q99986
REEFVETCPSEHKGV	MAP2	1266	P11137
EHKRIHTGEKPFTCE	ZNF141	216	Q15928
CGKTFPKNEEFVLHL	ZNF200	341	P98182
LCKFAHVPEQGDEKV	TOPAZ1	1111	Q8N9V7
DIKLSVKSFHCSGPV	TMEM87B	71	Q96K49
VEHERIHTGEKPFKC	ZNF852	371	Q6ZMS4
ERKISGCKHFEKPVS	ZNF528	126	Q3MIS6
KKFKCVTSHIVGPES	VSIG10	286	Q8N0Z9
VKHEIINSEERPFKC	ZNF23	156	P17027
GHEHEITKVACIPKS	WDR31	101	Q8NA23
LHEKTHIEGKPFICI	ZNF382	341	Q96SR6
GTAKKTAECIPKTHE	PPP1R1A	131	Q13522
TAECIPKTHERGSKE	PPP1R1A	136	Q13522
HVVDGKVPDTLRKCF	USP32	121	Q8NFA0
KDLTKTCEFIVHSAP	VPS26C	131	O14972
IHERTHTGEKPFECK	ZNF878	356	C9JN71
ECGKAFPRKSELTEH	ZNF649	266	Q9BS31
EECGKAFKHPSVLTT	ZNF737	316	O75373
EGFQLDPHTKACKAV	LDLR	381	P01130
CVYVVPDGETRKIKH	SLC8A1	186	P32418
AVHSAKEYIKGICEP	N4BP1	61	O75113
DFEKHKGCFTPVVTD	NEB	6441	P20929
VLLEKHEDKSPICDS	NEUROD4	181	Q9HD90
VTCKVEHESFEEPAL	NECTIN2	236	Q92692