Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	8.52e-08	431	108	14	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR5W2 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR5L2	4.43e-07	127	108	8	GO:0005549
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 ADGRB2 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	2.12e-05	884	108	16	GO:0004930
GeneOntologyMolecularFunction	phosphatase activity	DNAJC6 PPP1R3D PTPN3 PPP3CB SYNJ1 PLPP3 PTPRO PLPPR2	1.68e-04	287	108	8	GO:0016791
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	DNAJC6 PPP1R3D PTPN3 PPP3CB SYNJ1 PLPP3 PTPRO PLCG1 PLPPR2	2.49e-04	386	108	9	GO:0042578
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 ADGRB2 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR51J1 OR6P1 OR6A2 THBD PTPRO OR5L2 OR2H2	3.29e-04	1353	108	18	GO:0004888
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	DIS3L ASPG DNAJC6 ELAC2 PPP1R3D PTPN3 PPP3CB SYNJ1 PLPP3 PTPRO DDHD1 PLCG1 PLPPR2	4.16e-04	807	108	13	GO:0016788
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	5.91e-08	432	108	14	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	1.46e-07	465	108	14	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	2.43e-07	485	108	14	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 ROM1 OR5L2 OR2H2	3.73e-07	582	108	15	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	6.16e-07	524	108	14	GO:0009593
GeneOntologyBiologicalProcess	sensory perception	OR5W2 NPR2 OR10A2 OR6S1 OR5B12 GRK7 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR51J1 OR6P1 OR6A2 LRP2 ROM1 GJC3 OR5L2 OR2H2	6.49e-07	1072	108	20	GO:0007600
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	1.02e-06	547	108	14	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus	OR5W2 OR10A2 OR6S1 OR5B12 GRK7 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 ROM1 OR5L2 OR2H2	1.09e-06	722	108	16	GO:0051606
GeneOntologyBiologicalProcess	nitrobenzene metabolic process	GSTM1 GSTM4	1.62e-04	4	108	2	GO:0018916
GeneOntologyBiologicalProcess	mitochondrial RNA processing	ELAC2 FASTK SUPV3L1	2.00e-04	22	108	3	GO:0000963
Domain	Olfact_rcpt	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	3.94e-07	393	107	13	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	2.85e-05	670	107	14	IPR017452
Domain	7tm_1	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	3.19e-05	677	107	14	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	3.63e-05	685	107	14	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	3.99e-05	691	107	14	PS50262
Domain	GPCR_Rhodpsn	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 NMUR2 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	4.05e-05	692	107	14	IPR000276
Domain	CUB_dom	OVCH2 ZZEF1 SEZ6L2 CRHBP	3.18e-04	57	107	4	IPR000859
Domain	GST_mu	GSTM1 GSTM4	3.22e-04	5	107	2	IPR003081
Domain	APC_su10/DOC_dom	CUL9 ZZEF1	6.70e-04	7	107	2	IPR004939
Domain	DOC	CUL9 ZZEF1	6.70e-04	7	107	2	PS51284
Domain	ANAPC10	CUL9 ZZEF1	6.70e-04	7	107	2	PF03256
Domain	APC10	CUL9 ZZEF1	6.70e-04	7	107	2	SM01337
Domain	Rap_GAP	RALGAPA2 SIPA1L2	1.42e-03	10	107	2	PF02145
Domain	GST_C_3	GSTM1 GSTM4	1.42e-03	10	107	2	PF14497
Domain	Rap_GAP_dom	RALGAPA2 SIPA1L2	1.73e-03	11	107	2	IPR000331
Domain	RAPGAP	RALGAPA2 SIPA1L2	1.73e-03	11	107	2	PS50085
Domain	-	ZZEF1 SEZ6L2 CRHBP	3.30e-03	52	107	3	2.60.120.290
Domain	-	PLPP3 PLPPR2	4.69e-03	18	107	2	1.20.144.10
Domain	acidPPc	PLPP3 PLPPR2	4.69e-03	18	107	2	SM00014
Domain	P_Acid_Pase_2/haloperoxidase	PLPP3 PLPPR2	5.78e-03	20	107	2	IPR000326
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	5.76e-08	417	78	14	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR5W2 OR10A2 OR6S1 OR5B12 GRK7 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 LRP2 OR5L2 OR2H2	3.09e-07	636	78	16	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR6A2 OR5L2 OR2H2	9.08e-06	389	78	11	M14091
Pathway	WP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS	PPP3CB ITPRIP PLCG1	1.74e-04	20	78	3	M48330
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	3.87e-12	340	109	14	11875048
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	4.36e-12	343	109	14	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	4.90e-12	346	109	14	14611657
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5W2 OR10A2 OR5B12 OR5AS1 OR5B21 OR13G1 OR5A1 OR5AR1 OR51J1 OR6P1 OR6A2 OR5L2 OR2H2	5.97e-11	340	109	13	11802173
Pubmed	The human olfactory receptor gene family.	OR5W2 OR10A2 OR6S1 OR5B12 OR5AS1 OR13G1 OR5A1 OR5AR1 OR6P1 OR6A2 OR5L2 OR2H2	1.42e-07	541	109	12	14983052
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 B4GALNT4 SZT2 ARHGAP26 ADGRB2 NSD1 CUL9 RALGAPA2 ZZEF1 ITGB5 ELAC2 JAK3 SYNJ1 PLCG1 SIPA1L2 PRRC2B	3.62e-07	1105	109	16	35748872
Pubmed	Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.	GSTM1 GSTM4	9.73e-06	2	109	2	3174634
Pubmed	Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology.	DNAJC6 SYNJ1	9.73e-06	2	109	2	36792618
Pubmed	GST-M1 is transcribed moreso than AKR7A2 in AFB₁-exposed human monocytes and lymphocytes.	AKR7A2 GSTM1	9.73e-06	2	109	2	25027672
Pubmed	Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.	GSTM1 GSTM4	2.91e-05	3	109	2	8471052
Pubmed	Genetics of Parkinson's disease--state of the art, 2013.	DNAJC6 SYNJ1	2.91e-05	3	109	2	24262182
Pubmed	The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole.	GSTM1 GSTM4	2.91e-05	3	109	2	8512323
Pubmed	Differential and nonredundant roles of phospholipase Cgamma2 and phospholipase Cgamma1 in the terminal maturation of NK cells.	JAK3 PLCG1	2.91e-05	3	109	2	17015722
Pubmed	Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.	GSTM1 GSTM4	2.91e-05	3	109	2	27466493
Pubmed	Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.	GSTM1 GSTM4	2.91e-05	3	109	2	16549767
Pubmed	Genetic variants in vitamin d pathway genes and risk of pancreas cancer; results from a population-based case-control study in ontario, Canada.	CYP2R1 LRP2	5.82e-05	4	109	2	23826131
Pubmed	Primary Biliary Cholangitis in British Columbia First Nations: Clinical features and discovery of novel genetic susceptibility loci.	NTN1 DNMT1	5.82e-05	4	109	2	29297981
Pubmed	Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.	GSTM1 GSTM4	5.82e-05	4	109	2	8373352
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR5W2 OR10A2 OR5B12 OR5A1 OR5L2 OR2H2	6.87e-05	219	109	6	12213199
Pubmed	Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.	GSTM1 GSTM4	9.67e-05	5	109	2	19856098
Pubmed	Glutathione S-transferase variants and hypertension.	GSTM1 GSTM4	9.67e-05	5	109	2	18551009
Pubmed	Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.	FRY LRP2 SIPA1L2	1.39e-04	32	109	3	25189868
Pubmed	Netrin-1/DCC-mediated PLCγ1 activation is required for axon guidance and brain structure development.	NTN1 PLCG1	1.45e-04	6	109	2	30224412
Pubmed	Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.	GSTM1 GSTM4	1.45e-04	6	109	2	1530570
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ADGRB2 DNAJC6 CYFIP1 PPP3CB SYNJ1 PLPP3	1.45e-04	251	109	6	27507650
Pubmed	Vitamin D.	CYP2R1 LRP2	2.02e-04	7	109	2	15951480
Pubmed	Analysis of polymorphic patterns in candidate genes in Israeli patients with prostate cancer.	ELAC2 GSTM1	2.69e-04	8	109	2	14719475
Pubmed	Exome sequencing supports a de novo mutational paradigm for schizophrenia.	RB1CC1 CFAP65 EDEM2	2.72e-04	40	109	3	21822266
Pubmed	Genomic analysis of orthologous mouse and human olfactory receptor loci.	OR10A2 OR6A2	3.45e-04	9	109	2	11416212
Pubmed	Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling.	JAK3 PLCG1	3.45e-04	9	109	2	9045636
Pubmed	The sperm-associated antigen 6 interactome and its role in spermatogenesis.	COPB1 NMUR2 GSTM1 PPP3CB DDHD1	4.21e-04	199	109	5	31146259
Pubmed	Autophagy proteins control goblet cell function by potentiating reactive oxygen species production.	NCF1 RB1CC1	4.31e-04	10	109	2	24185898
Pubmed	Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction.	TPO THBD	4.31e-04	10	109	2	20036902
Pubmed	TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.	HMGB2 RB1CC1 GGCT PPIL2	5.15e-04	117	109	4	36898370
Pubmed	Specificity of the binding of synapsin I to Src homology 3 domains.	NCF1 PLCG1	5.26e-04	11	109	2	10899172
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TICRR ARHGAP26 NSD1 MSH5 PPP2R5C PPP3CB SYNJ1 DDHD1 LRP2 ITPRIP PLCG1	6.09e-04	1084	109	11	11544199
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	COPB1 DIS3L GATM CUL9 FRY PPP3CB SYNJ1 SUPV3L1 LRP2 PLCG1 QKI DNMT1	7.12e-04	1285	109	12	35914814
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	SZT2 DNAJC6 VPS13D	7.36e-04	56	109	3	9455484
Pubmed	Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.	ADGRB2 LRP2	7.42e-04	13	109	2	12508107
Pubmed	Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.	ASPG GATM GSTM1 LRP2	8.11e-04	132	109	4	22496890
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ADGRB2 NSD1 DNAJC6 FRY CYFIP1 PPP3CB SYNJ1 PLPP3 PRRC2B DNMT1	9.11e-04	963	109	10	28671696
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ARHGAP26 JMJD4 DNAJC6 PTPN3 CYFIP1 PTPRO PLCG1 SIPA1L2 QKI PRRC2B	9.93e-04	974	109	10	28675297
Pubmed	Early life environment, neurodevelopment and the interrelation with atopy.	DPP10 GSTM1	1.13e-03	16	109	2	20701904
Pubmed	CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing.	NSD1 DNMT1	1.13e-03	16	109	2	24292684
Pubmed	Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation.	TPO ROM1	1.13e-03	16	109	2	8630490
Pubmed	Genomic analysis of mouse retinal development.	NSD1 CUL9 HMGB2 SEZ6L2 CRHBP FANCC PPP2R5C PLPP3 PLPPR2 PRRC2B	1.26e-03	1006	109	10	15226823
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR5AR1 OR6A2	1.28e-03	17	109	2	20668191
Pubmed	Emx2 stimulates odorant receptor gene expression.	OR6A2 OR2H2	1.28e-03	17	109	2	18854508
Pubmed	MORC2B is essential for meiotic progression and fertility.	MSH5 CFAP65	1.44e-03	18	109	2	29329290
Pubmed	Low 8-oxo-7,8-dihydro-2'-deoxyguanosine levels and influence of genetic background in an Andean population exposed to high levels of arsenic.	GSTM1 DNMT1	1.44e-03	18	109	2	19896490
Pubmed	Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.	FRAS1 SIPA1L2	1.44e-03	18	109	2	20602751
Pubmed	Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.	OR6P1 OR6A2	1.44e-03	18	109	2	20550939
Pubmed	Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.	COPB1 CYP2R1	1.61e-03	19	109	2	25208829
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	NLGN4Y ADGRB2 CYFIP1 PPP3CB SYNJ1	1.96e-03	281	109	5	28706196
Pubmed	Cul3-Klhl18 ubiquitin ligase modulates rod transducin translocation during light-dark adaptation.	PPP3CB ROM1	1.97e-03	21	109	2	31696965
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	OVCH2 OR10A2 ROM1	2.06e-03	80	109	3	16554811
Pubmed	Genetic analysis of 22 candidate genes for hypertension in the Japanese population.	GSTM1 HSD11B2	2.16e-03	22	109	2	15167446
Pubmed	NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.	ARHGAP26 CYFIP1	2.16e-03	22	109	2	21946561
Pubmed	Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity.	PPP3CB PLCG1	2.36e-03	23	109	2	20379146
Pubmed	The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.	ATRIP PRRC2B	2.36e-03	23	109	2	17203973
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	COPB1 ADGRB2 ITGB5	2.37e-03	84	109	3	15123239
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	PPP3CB SYNJ1 FASTK	2.45e-03	85	109	3	23055939
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCF1 CUL9 CYFIP1 SYNJ1 PPIL2 SIPA1L2 PRRC2B	2.57e-03	588	109	7	38580884
Pubmed	Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.	LRP2 QKI	2.79e-03	25	109	2	23554936
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5W2 OR5B12 OR5AS1 OR5B21 OR5A1 OR5AR1 ROM1 OR5L2	1.84e-06	345	109	8	chr11q12
Cytoband	11q12.1	OR5B12 OR5AS1 OR5B21 OR5A1 OR5AR1	4.34e-05	161	109	5	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	B4GALNT4 OVCH2 OR10A2 COPB1 OR51J1 OR6A2 CYP2R1	4.12e-04	564	109	7	chr11p15
Cytoband	11p15.2	COPB1 CYP2R1	5.75e-04	15	109	2	11p15.2
Cytoband	1p13.3	CHI3L2 GSTM1 GSTM4	6.09e-04	69	109	3	1p13.3
GeneFamily	Olfactory receptors, family 5	OR5W2 OR5B12 OR5AS1 OR5B21 OR5A1 OR5AR1 OR5L2	4.06e-07	112	75	7	152
GeneFamily	Olfactory receptors, family 6	OR6S1 OR6P1 OR6A2	1.24e-03	51	75	3	153
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR ARHGAP26 GATM HMGB2 CFAP65 MAP3K15 DNMT1	2.13e-07	172	108	7	eba1568d4307e91c94fc616549057cbed8df5840
Disease	Atypical juvenile parkinsonism	DNAJC6 SYNJ1	3.83e-05	3	106	2	C4510873
Disease	Brugada syndrome (implicated_via_orthology)	GSTM1 GSTM4	1.27e-04	5	106	2	DOID:0050451 (implicated_via_orthology)
Disease	pack-years measurement, systolic blood pressure	FRY LRP2 SIPA1L2	2.49e-04	34	106	3	EFO_0006335, EFO_0006526
Disease	autism spectrum disorder (is_marker_for)	SRSF11 CYFIP1	2.65e-04	7	106	2	DOID:0060041 (is_marker_for)
Disease	juvenile myelomonocytic leukemia (is_implicated_in)	ARHGAP26 JAK3	2.65e-04	7	106	2	DOID:0050458 (is_implicated_in)
Disease	cortical surface area measurement	EFCAB5 TICRR NPR2 CHRDL2 COPB1 OR5B12 OR5B21 CUL9 MSH5 ITGB5 ELAC2 EDEM2 C8orf82 NTN1	3.28e-04	1345	106	14	EFO_0010736
Disease	Fanconi anemia (is_implicated_in)	GSTM1 FANCC	5.65e-04	10	106	2	DOID:13636 (is_implicated_in)
Disease	Metabolic Bone Disorder	CYP2R1 LRP2	1.13e-03	14	106	2	C0005944
Disease	rostral middle frontal gyrus volume measurement	ADGB NTN1	1.13e-03	14	106	2	EFO_0010328
Disease	Osteopenia	CYP2R1 LRP2	1.30e-03	15	106	2	C0029453
Disease	thyroglobulin measurement	OR5B12 OR5B21	1.48e-03	16	106	2	EFO_0010050
Disease	lung non-small cell carcinoma (is_implicated_in)	MSH5 PLCG1 SDHC DNMT1	1.62e-03	139	106	4	DOID:3908 (is_implicated_in)
Disease	Chronic myeloproliferative disorder	JAK3 ATRIP	2.10e-03	19	106	2	C1292778
Disease	Juvenile Myelomonocytic Leukemia	ARHGAP26 JAK3	2.10e-03	19	106	2	C0349639
Disease	Liver carcinoma	TICRR ASPG HMGB2 MSH5 DNAJC6 CRHBP GSTM1	2.40e-03	507	106	7	C2239176
Disease	Parkinson's disease (is_implicated_in)	DNAJC6 GSTM1 SYNJ1	2.62e-03	76	106	3	DOID:14330 (is_implicated_in)
Disease	schizophrenia (is_implicated_in)	GSTM1 CYFIP1 CACNA1I	2.82e-03	78	106	3	DOID:5419 (is_implicated_in)
Disease	Asthma	GSTM1 HSD11B2 DNMT1	3.03e-03	80	106	3	C0004096
Disease	acute myeloid leukemia (is_implicated_in)	NSD1 GSTM1 FANCC	3.48e-03	84	106	3	DOID:9119 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QEQVCAHFAPRLLPL	ADGRB2	86	O60241
QVETELFPCLRHFGL	AKR7A2	206	O43488
AFPFLSPCGRERNFL	C8orf82	91	Q6P1X6
VQCITFPIEFNHRPL	CCIN	456	Q13939
LFPEPLHVFAPRACQ	DNMT1	1326	P26358
HVVLPNFEPESCRFT	ADGB	776	Q8N7X0
DLRCLNISFLHPQRF	A4GNT	246	Q9UNA3
PLFRQLAKCVSSPHF	PPP2R5C	326	Q13362
FTPENIDPFLCSHLI	CHI3L2	46	Q15782
FNHLTRFIGACIDPP	NPR2	576	P20594
FFISHCLPRALQPGQ	HSD11B2	366	P80365
NQHFLLFCEGPRVPV	DPP10	486	Q8N608
GHPRRCIPDFVNAAF	NTN1	46	O95631
HPLPLDVLEDIFCRF	RBM45	401	Q8IUH3
PAAFHRECLNIDIPE	NSD1	1726	Q96L73
RLPFDHCSLSLQPFV	PPIL2	36	Q13356
LPNFCGIFNHLERLL	QKI	31	Q96PU8
QVDRPLLCHLFVPFT	ITPRIP	201	Q8IWB1
QHFFCKEVAPPRLLE	JAK3	356	P52333
CTLHFRVRFFIPDPN	PTPN3	101	P26045
EPCILHFQVLFENPL	PCDHB18P	46	Q96TA0
SNEINHFFCDIPPLL	OR5W2	171	Q8NH69
FLRVPLLCDFEPLHQ	RB1CC1	596	Q8TDY2
RNFVGPPHFQVICRL	CYFIP1	906	Q7L576
RCLPFRALHFVFSPG	FASTK	326	Q14296
KAACFDAFHPLSPLR	GJC3	61	Q8NFK1
IDHFFCEIPPLLALS	OR13G1	171	Q8NGZ3
TLHLPFCPDRQVDDF	OR2H2	161	O95918
EINHFFCDIPPLLAL	OR5B21	171	A6NL26
CTAHAPERFLIPIAF	FRAS1	3631	Q86XX4
LLLHLFRAPQACFLP	MED12L	1131	Q86YW9
LCGPRRSHFFLPVSV	NMUR2	36	Q9GZQ4
VLSNPDRPCHQIDLF	GATM	316	P50440
CHRALPVFEQFPLVD	HECA	401	Q9UBI9
ARRFAAFCSPNLLPL	ASPG	191	Q86U10
KRPPSAFFLFCSEHR	HMGB2	96	P26583
FQPTHPIICFRRVAC	CFAP65	531	Q6ZU64
ELAAFQAEHRACLPP	KCNK7	46	Q9Y2U2
LENAFPFDELRPLTC	EDEM2	51	Q9BV94
SLEACLFPDVLHPFF	OR51J1	96	Q9H342
IINHFFCDLPPVLAL	OR5A1	176	Q8NGJ0
ENFLPRARTGPLFAC	TPO	641	P07202
CPHLLDFFKVRPDDL	NCF1	111	P14598
HPNEFIRGSTLRFLC	COPB1	111	P53618
IHLRNPSAAFFCVAR	GGCT	31	O75223
LLLAPSTRNFFCHPL	KCNS1	291	Q96KK3
HLCLDVPCNSPNRFR	LRP2	3876	P98164
VVEHFFCDAPPLLTL	OR5B12	171	Q96R08
AHELFPSRLPNQCVL	CHRDL2	126	Q6WN34
NTIIRHCPPRFFSLG	RALGAPA2	1056	Q2PPJ7
KLFPNCVPSFGFRHL	ITGB5	206	P18084
CVPSFGFRHLLPLTD	ITGB5	211	P18084
SNIVNHFFCDIPPLL	OR5AS1	171	Q8N127
DIPHFAADLPLNRCK	PTPRO	951	Q16827
VNHFFCDSPPVLRLV	OR10A2	161	Q9H208
PHLKRSFSIIPCFVF	PLPPR2	6	Q96GM1
FSAVCPQHLDERFLL	NLGN4Y	106	Q8NFZ3
PNIINHFFCDISPLL	OR6P1	171	Q8NGX9
VVQHFFCDSGPLLRL	OR6S1	176	Q8NH40
NPPTIHRKSCIFRDF	EFCAB5	1216	A4FU69
RPQLHCAAFFISEPE	CRHBP	76	P24387
HQSEIFADRPCLPLF	CYP2R1	101	Q6VVX0
PPHQEFFSELRECAK	DIS3L	711	Q8TF46
HPDLAPIAFFCLRQT	CACNA1I	51	Q9P0X4
HLCRDFPVEDVFTLP	JMJD4	186	Q9H9V9
AHFSPQLCIRNAVPL	SDHC	16	Q99643
LPQAACHPAIFRVVD	FANCC	281	Q00597
PIRQAPSLHNLFAVC	DNAJC6	131	O75061
TPPLFHLDFLCCQLR	C2CD4D	191	B7Z1M9
FCPRPFETPLSHLRQ	FAM47A	301	Q5JRC9
IPFFDVFLRHLCQGS	CUL9	1146	Q8IWT3
CNRLLNIFHPTDPVA	DDHD1	651	Q8NEL9
LFSFLRQENLPKHCP	FRY	856	Q5TBA9
LIQCVPVHHRRFLFP	FRY	1101	Q5TBA9
RAFPLCQLPGAVHFL	ATRIP	406	Q8WXE1
CQLPGAVHFLPLVQF	ATRIP	411	Q8WXE1
FHSLCEQQPIGRRLF	GRK7	56	Q8WTQ7
AIRGFSPPHRICSFE	PPP3CB	466	P16298
PNIINHFFCDVSPLL	OR6A2	176	O95222
RGPTCPHIFVATNFL	MSH5	696	O43196
ARAFILSCFEPDPHK	MAP3K15	881	Q6ZN16
LLSRFPQSCRHFQSP	SZT2	3341	Q5T011
LCEFHFPATCRPLAV	THBD	166	P07204
VCLFVFIRPQHAPFI	SYNJ1	636	O43426
IGRLRPHFLSVCNPD	PLPP3	151	O14495
HFVGPICLPELREQF	OVCH2	156	Q7RTZ1
LHRIFEPNCLDAFPN	GSTM4	166	Q03013
LHRIFEPKCLDAFPN	GSTM1	166	P09488
LCVSRHPVFFLTVPA	PTCHD4	36	Q6ZW05
NFVPCHPNLHLLFDR	ARHGAP26	731	Q9UNA1
PEFFRCDPAISPSLH	SIPA1L2	231	Q9P2F8
FVLHFKEVPRNDTCP	SEZ6L2	631	Q6UXD5
RAAICSALRPHFGPF	SUPV3L1	21	Q8IYB8
SNIINHFFCEIPPLL	OR5AR1	171	Q8NGP9
SNVINHFFCDLPPLL	OR5L2	171	Q8NGL0
EHQLPPASRCVLVFE	SOAT2	221	O75908
VFLCDLHIHFPPNIL	B4GALNT4	911	Q76KP1
VNAVFLLAPCPHSQR	TICRR	151	Q7Z2Z1
LLAPCPHSQRELLQF	TICRR	156	Q7Z2Z1
LIHPDIFPLLTSFRC	ELAC2	391	Q9BQ52
PLPVSSRVCFVKFHD	SRSF11	71	Q05519
LRHLGTFLAPSCQFP	ROM1	46	Q03395
LDLPPFQNCIGTIHF	THAP9	496	Q9H5L6
NLQEIFLPAFPCHER	ZDHHC4	326	Q9NPG8
PLCARTFRQSALLFH	ZNF672	131	Q499Z4
GPCRTIRPFFHALSV	TXNDC2	481	Q86VQ3
CLRIPSAFRHLFTQP	TMEM135	271	Q86UB9
DPAFRPDQSHCFVIL	PLCG1	96	P19174
QDLEFTLHCLVPDFP	PPP1R3D	146	O95685
HTQNLRCSPLEPDFV	PRRC2B	846	Q5JSZ5
NIPDDPCRHFLLDFA	ZZEF1	1281	O43149
PCRHFLLDFAQSEPA	ZZEF1	1286	O43149
LLCDDLFSHQPFPRG	SCML4	196	Q8N228
PFVPFALRNHTGCTL	VPS13D	2886	Q5THJ4