Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentGolgi lumen

MUC16 MUC5B MUC4 MUC5AC

1.73e-05109304GO:0005796
MousePhenoabnormal hepatic cord morphology

PILRB PILRA

4.22e-056242MP:0012246
MousePhenoincreased circulating interferon-gamma level

PILRB PILRA MUC5AC

9.30e-0552243MP:0008577
MousePhenoincreased interferon level

PILRB PILRA MUC5AC

2.35e-0471243MP:0014435
MousePhenoincreased susceptibility to infection induced morbidity/mortality

MUC5B PILRB PILRA MUC4

2.56e-04185244MP:0009787
MousePhenoabnormal circulating interleukin-1 level

PILRB PILRA IL1R2

2.77e-0475243MP:0008589
MousePhenoincreased cytokine level

PILRB PILRA MUC5AC

2.77e-0475243MP:0014433
MousePhenoabnormal circulating interferon-gamma level

PILRB PILRA MUC5AC

3.60e-0482243MP:0008551
DomainVWFD

MUC5B MUC4 MUC5AC

1.67e-0616283PS51233
DomainVWD

MUC5B MUC4 MUC5AC

1.67e-0616283SM00216
DomainVWF_type-D

MUC5B MUC4 MUC5AC

1.67e-0616283IPR001846
DomainVWD

MUC5B MUC4 MUC5AC

1.67e-0616283PF00094
DomainWxxW_domain

MUC5B MUC5AC

3.24e-056282IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

3.24e-056282PF13330
Domain-

LRRN2 IGF1R DSCAM PILRB TNR PILRA IL1R2

4.25e-056632872.60.40.10
DomainIg-like_fold

LRRN2 IGF1R DSCAM PILRB TNR PILRA IL1R2

6.33e-05706287IPR013783
DomainTIL

MUC5B MUC5AC

1.42e-0412282PF01826
DomainC8

MUC5B MUC5AC

1.42e-0412282PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC

1.67e-0413282IPR014853
DomainC8

MUC5B MUC5AC

1.67e-0413282SM00832
DomainTIL_dom

MUC5B MUC5AC

1.95e-0414282IPR002919
DomainGlyco_hormone_CN

MUC5B MUC5AC

2.25e-0415282IPR006208
DomainCys_knot

MUC5B MUC5AC

2.25e-0415282PF00007
DomainCTCK_1

MUC5B MUC5AC

3.27e-0418282PS01185
DomainIG

LRRN2 DSCAM PILRB PILRA IL1R2

3.64e-04421285SM00409
DomainIg_sub

LRRN2 DSCAM PILRB PILRA IL1R2

3.64e-04421285IPR003599
DomainVWC_out

MUC5B MUC5AC

3.65e-0419282SM00215
DomainCT

MUC5B MUC5AC

4.91e-0422282SM00041
DomainCys_knot_C

MUC5B MUC5AC

6.36e-0425282IPR006207
DomainCTCK_2

MUC5B MUC5AC

6.36e-0425282PS01225
DomainIG_LIKE

LRRN2 DSCAM PILRB PILRA IL1R2

7.33e-04491285PS50835
DomainVWC

MUC5B MUC5AC

8.00e-0428282PF00093
DomainIg-like_dom

LRRN2 DSCAM PILRB PILRA IL1R2

8.17e-04503285IPR007110
DomainVWFC_1

MUC5B MUC5AC

1.32e-0336282PS01208
DomainVWC

MUC5B MUC5AC

1.47e-0338282SM00214
DomainKH_1

ANKRD17 TDRKH

1.47e-0338282PF00013
DomainVWFC_2

MUC5B MUC5AC

1.47e-0338282PS50184
Domain-

ANKRD17 TDRKH

1.55e-03392823.30.1370.10
DomainKH

ANKRD17 TDRKH

1.63e-0340282SM00322
DomainKH_dom

ANKRD17 TDRKH

1.63e-0340282IPR004087
Domainfn3

IGF1R DSCAM TNR

1.79e-03162283PF00041
DomainKH_TYPE_1

ANKRD17 TDRKH

1.80e-0342282PS50084
DomainVWF_dom

MUC5B MUC5AC

1.80e-0342282IPR001007
DomainKH_dom_type_1

ANKRD17 TDRKH

1.97e-0344282IPR004088
DomainFN3

IGF1R DSCAM TNR

2.61e-03185283SM00060
DomainFN3

IGF1R DSCAM TNR

3.21e-03199283PS50853
DomainIg_V-set

DSCAM PILRB PILRA

3.21e-03199283IPR013106
DomainFN3_dom

IGF1R DSCAM TNR

3.68e-03209283IPR003961
DomainIGc2

LRRN2 DSCAM IL1R2

5.11e-03235283SM00408
DomainIg_sub2

LRRN2 DSCAM IL1R2

5.11e-03235283IPR003598
DomainANK_REPEAT

MUC16 ANKRD17 HECTD1

6.27e-03253283PS50088
DomainANK_REP_REGION

MUC16 ANKRD17 HECTD1

6.33e-03254283PS50297
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC4 MUC5AC

6.55e-0916214M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC4 MUC5AC

8.55e-0917214M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4 MUC5AC

2.14e-0821214MM15706
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4 MUC5AC

3.16e-0823214M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC4 MUC5AC

5.33e-0826214M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC4 MUC5AC

1.68e-0660214MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC4 MUC5AC

1.92e-0662214M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC4 MUC5AC

2.79e-0668214M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC4 MUC5AC

1.83e-05109214MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC4 MUC5AC

1.97e-05111214M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC4 MUC5AC

4.89e-05140214M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC4 MUC5AC

5.31e-05143214M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 MUC5B MUC4 MUC5AC

4.56e-04250214M27554
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC4 MUC5AC

1.36e-091830418834073
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4 MUC5AC

5.78e-09530311062147
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC5AC

1.16e-08630319110483
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

7.19e-0723027513696
Pubmed

Modulation of paired immunoglobulin-like type 2 receptor signaling alters the host response to Staphylococcus aureus-induced pneumonia.

PILRB PILRA

7.19e-07230220065029
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

7.19e-07230223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

7.19e-07230231030254
Pubmed

A single-amino-acid substitution in herpes simplex virus 1 envelope glycoprotein B at a site required for binding to the paired immunoglobulin-like type 2 receptor alpha (PILRalpha) abrogates PILRalpha-dependent viral entry and reduces pathogenesis.

PILRB PILRA

7.19e-07230220686018
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

7.19e-07230227729120
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

7.19e-07230234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

7.19e-07230237146737
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

7.19e-07230223527003
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

7.19e-07230214988081
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

7.19e-07230216540890
Pubmed

PILRα and PILRβ have a siglec fold and provide the basis of binding to sialic acid.

PILRB PILRA

7.19e-07230224843130
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

7.19e-07230215563276
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

7.19e-07230236111525
Pubmed

Alterations of the ocular surface epithelial MUC16 and goblet cell MUC5AC in patients with atopic keratoconjunctivitis.

MUC16 MUC5AC

7.19e-07230218782111
Pubmed

PILRα negatively regulates mouse inflammatory arthritis.

PILRB PILRA

7.19e-07230224935926
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

7.19e-07230217621824
Pubmed

MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer.

MUC4 MUC5AC

7.19e-07230218475301
Pubmed

Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers.

MUC16 MUC5AC

7.19e-07230222220206
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

7.19e-07230224317696
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

7.19e-07230227845589
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

7.19e-07230222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

7.19e-07230214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

7.19e-07230235776514
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

7.19e-07230227435107
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

7.19e-07230223544943
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

7.19e-07230224327612
Pubmed

The Ig-like v-type domain of paired Ig-like type 2 receptor alpha is critical for herpes simplex virus type 1-mediated membrane fusion.

PILRB PILRA

7.19e-07230220573830
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

7.19e-07230226871672
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

7.19e-07230221653907
Pubmed

Monocyte infiltration into obese and fibrilized tissues is regulated by PILRα.

PILRB PILRA

7.19e-07230226840635
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

7.19e-07230236427316
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

7.19e-07230214690056
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

7.19e-07230232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

7.19e-07230211587997
Pubmed

Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation.

PILRB PILRA

7.19e-07230223142774
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

7.19e-07230228607090
Pubmed

Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.

MUC4 MUC5AC

7.19e-07230219158956
Pubmed

Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer.

MUC16 MUC5AC

7.19e-07230224722639
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

7.19e-07230224332705
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

7.19e-07230234656442
Pubmed

Blood flow guides sequential support of neutrophil arrest and diapedesis by PILR-β1 and PILR-α.

PILRB PILRA

2.16e-06330231385804
Pubmed

Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren's syndrome-associated dry eyes.

MUC16 MUC5AC

2.16e-06330233232357
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

2.16e-06330227776277
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

2.16e-06330223053434
Pubmed

The CD8α-PILRα interaction maintains CD8+ T cell quiescence.

PILRB PILRA

2.16e-06330235617401
Pubmed

The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production.

PILRB PILRA

2.16e-06330222479310
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

2.16e-06330234158522
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

2.16e-06330229604272
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

2.16e-06330229286856
Pubmed

PANP is a novel O-glycosylated PILRα ligand expressed in neural tissues.

PILRB PILRA

2.16e-06330221241660
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

2.16e-06330219596978
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

2.16e-06330227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

2.16e-06330230236127
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

2.16e-06330235879412
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

2.16e-06330236675209
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

2.16e-06330219556605
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC4 MUC5AC

2.16e-06330223464473
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

2.16e-06330217592322
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

2.16e-06330221455588
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

2.16e-06330229802623
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

2.16e-06330220422702
Pubmed

Counter-regulation of the ligand-receptor pair Leda-1/Pianp and Pilrα during the LPS-mediated immune response of murine macrophages.

PILRB PILRA

2.16e-06330226188512
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

2.16e-06330227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

2.16e-06330224204560
Pubmed

Negative regulation of DSS-induced experimental colitis by PILRα.

PILRB PILRA

2.16e-06330225710489
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

2.16e-06330224939955
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

2.16e-06330219718741
Pubmed

Evolutionarily conserved paired immunoglobulin-like receptor α (PILRα) domain mediates its interaction with diverse sialylated ligands.

PILRB PILRA

4.31e-06430222396535
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5B MUC5AC

4.31e-06430231582416
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC5AC

4.31e-06430223807779
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC5AC

4.31e-06430225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC5AC

4.31e-06430217471237
Pubmed

Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.

PILRB PILRA

4.31e-06430214970179
Pubmed

MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.

MUC5B MUC5AC

4.31e-06430221097527
Pubmed

TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

MUC16 MUC4

4.31e-06430239024979
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC5AC

4.31e-06430222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC5AC

4.31e-06430214984930
Pubmed

TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.

MUC5B MUC5AC

4.31e-06430223249391
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC5AC

4.31e-06430212676567
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC5AC

4.31e-06430229869461
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

MUC5B MUC5AC

4.31e-06430218258655
Pubmed

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair.

MUC5B IL1R2 MUC5AC

6.50e-064230331776260
Pubmed

FDF03, a novel inhibitory receptor of the immunoglobulin superfamily, is expressed by human dendritic and myeloid cells.

PILRB PILRA

7.18e-06530210903717
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC5AC

7.18e-06530216188033
Pubmed

Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes.

PILRB PILRA

7.18e-06530216926269
Pubmed

MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.

MUC4 MUC5AC

7.18e-06530216475027
Pubmed

PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif-bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta.

PILRB PILRA

1.51e-05730210660620
Pubmed

Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.

PILRB PILRA

2.01e-05830227349870
Pubmed

An essential role of sialylated O-linked sugar chains in the recognition of mouse CD99 by paired Ig-like type 2 receptor (PILR).

PILRB PILRA

2.01e-05830218209065
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ANKRD17 PARP14 CCT3 HECTD1

2.69e-0520230433005030
Pubmed

Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.

MUC5B MUC4 IL1R2 MUC5AC

2.79e-0520430420503287
Pubmed

Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.

MUC5B MUC4 IL1R2 MUC5AC

2.85e-0520530419258923
Pubmed

Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.

MUC5B MUC4 IL1R2 MUC5AC

2.96e-0520730417703412
Pubmed

Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development.

PILRB PILRA

3.22e-051030218802077
Pubmed

Epithelial colonization by gut dendritic cells promotes their functional diversification.

PILRB PILRA

3.22e-051030234910930
Pubmed

Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.

MUC5B MUC5AC

3.94e-051130224429156
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC4 MUC5AC

1.17e-0821234648
GeneFamilyFibronectin type III domain containing

IGF1R DSCAM TNR PTPRQ

4.59e-05160234555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRRN2 DSCAM

1.76e-02161232593
GeneFamilyAdenosine receptors|V-set domain containing

PILRB PILRA

1.81e-02163232590
GeneFamilyImmunoglobulin like domain containing

DSCAM IL1R2

2.48e-02193232594
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC4 MUC5AC

3.08e-05158304MM17063
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC4 MUC5AC

4.10e-05170304M5880
CoexpressionAtlasMyeloid Cells, DC.103+11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103+ F4/80-lo, Small Intestine, avg-4

PILRB PILRA IL1R2

6.72e-0558293GSM854237_100
CoexpressionAtlasMyeloid Cells, DC.103+11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103+ F480-, Small Intestine, avg-5

PILRB PILRA IL1R2

1.13e-0469293GSM854232_100
CoexpressionAtlasMyeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3

PILRB PILRA IL1R2

1.23e-0471293GSM854312_100
CoexpressionAtlasBM Top 100 - trachea

MUC16 MUC4 MUC5AC

1.28e-0472293BM Top 100 - trachea
CoexpressionAtlasMyeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3

PILRB PILRA IL1R2

1.39e-0474293GSM854309_100
CoexpressionAtlasMyeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7

PILRB PILRA IL1R2

1.45e-0475293GSM854262_100
CoexpressionAtlasBM Top 100 - bronchus

MUC5B MUC4 MUC5AC

1.51e-0476293BM Top 100 - bronchus
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#3_top-relative-expression-ranked_200

MUC16 ADGRD1 PTPRQ

4.48e-04110293gudmap_kidney_adult_RenalCapsule_k3_200
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MUC5B IGF1R DSCAM PILRA MUC4 IL1R2

1.10e-091623069c9a63adb692651ea5a52cc77b02c5ce11d0ccea
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B IGF1R DSCAM PILRA MUC4 IL1R2

1.10e-09162306dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MUC5B IGF1R DSCAM PILRA MUC4 IL1R2

1.10e-091623061d29983b22f963b34e72cfd1eec328d2d7c4932f
ToppCelldroplet-Lung-LUNG-30m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B IGF1R DSCAM PILRA MUC4 IL1R2

1.10e-091623062a4e09545e9874519f0f56e81065104987d81cd6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B DSCAM MUC4 MUC5AC

6.87e-0815930560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.05e-07173305464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.58e-071883055901b276f2379abf486b8285957277e95f08464e
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.80e-0719330571bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.80e-07193305b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.85e-07194305d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.94e-07196305c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.94e-071963057a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.94e-07196305a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.94e-0719630560ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.99e-07197305da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.99e-07197305a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

1.99e-071973053fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.04e-071983053477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.04e-07198305da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.04e-07198305e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.04e-07198305af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.10e-071993057223f853335492ca617dbec3e4b6872a8a463a45
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.10e-0719930570c0b9cff195d3d24e98443a729e211cac20c90f
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.10e-07199305e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.10e-07199305ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.10e-07199305a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC5B MUC4 MUC5AC

2.15e-07200305133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC5AC

3.46e-0615530462b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4 MUC5AC

4.33e-061643046e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 FAM83D MUC4 MUC5AC

5.11e-0617130425c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 FAM83D MUC4 MUC5AC

5.11e-06171304fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC16 FAM83D MUC5B MUC5AC

5.47e-061743047d2f802f493f19a068e097b2909a9000e2160266
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

5.47e-0617430442f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

5.60e-061753048252ddc2ca95071381f0354aefb70c4714828491
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

5.60e-061753048ccf60fc469059d7aaf4e6ce54159db2962e0060
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

5.99e-061783049a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

5.99e-0617830419b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

5.99e-06178304b413a634283550fa224db7d0d05956e3f64694a1
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

5.99e-0617830449a2271718637522f74334068d252963ee13b1ce
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

6.12e-061793046e965e424eebef50f0202cff75f458be395cfca1
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

MUC16 FAM83D MUC5B MUC5AC

6.12e-061793041fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC4 MUC5AC

6.12e-06179304859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 MUC5AC

6.26e-06180304d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC4 MUC5AC

6.26e-061803043dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC4 MUC5AC

6.26e-06180304668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4 MUC5AC

6.54e-061823043f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC4 MUC5AC

6.68e-0618330415d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4 MUC5AC

6.68e-06183304940cbe298e9c53b5622af09264586ed823d3141f
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC4 MUC5AC

6.83e-06184304d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

6.83e-0618430401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellSevere_COVID-19-Epithelial-undefined_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MUC16 MUC5B MUC4 MUC5AC

7.59e-061893048cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PARP14 MUC4 MUC5AC

7.75e-061903046ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MUC16 MUC5B MUC4 MUC5AC

7.75e-0619030451ca9ef4df3220487152fcf684147730637c7cc1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

7.75e-061903043c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

7.75e-0619030423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

7.91e-06191304529068029fb461df766135576dd0d8b5980f9bc0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 MUC5B MUC4 MUC5AC

8.08e-06192304612be3f861bd2f71a31c57f48c8b10930c3471ea
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 MUC5B MUC4 MUC5AC

8.08e-06192304f627a3f43e2340c8ba502211940171f25c7ff436
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

8.24e-06193304605fc2a25ed6846fb283b2918cfed98df6039d6b
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 MUC5AC

8.24e-061933049d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B MUC4 MUC5AC

8.41e-06194304e0228f593c3493175962a4817500d4337ddc4e88
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 MUC5AC

8.58e-06195304b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 MUC5B MUC4 MUC5AC

8.58e-06195304b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC16 PARP14 MUC4 MUC5AC

8.58e-061953047509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B MUC4 MUC5AC

8.58e-06195304e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304808c0a7d1889a8f3508ed9790c6dc7ec16bbc840
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

8.76e-0619630491a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell(05)_Secretory|World / shred by cell type by condition

MUC16 MUC5B MUC4 MUC5AC

8.76e-061963048032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC4 MUC5AC

8.76e-06196304b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM83D MUC4 MUC5AC

8.76e-06196304c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC16 FAM83D MUC5B MUC5AC

8.76e-06196304057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 MUC5B MUC4 MUC5AC

8.76e-06196304b246e482f012dd9782b49c2a953acedfa3c1139d
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC16 FAM83D MUC5B MUC5AC

8.94e-061973043f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

MUC16 MUC5B MUC4 MUC5AC

8.94e-06197304b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC5AC

8.94e-06197304ff19e4c45715752a04541ad6a0cdf5454c9daaa2
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MUC16 MUC5B MUC4 MUC5AC

8.94e-061973044cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B MUC4 MUC5AC

9.12e-061983045dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC5AC

9.12e-061983047896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 MUC5B MUC4 MUC5AC

9.12e-06198304484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC5B MUC5AC

9.12e-06198304778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

9.30e-061993041e693d7bb481bf03a943b460a69787229625d7b1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 FAM83D MUC4 MUC5AC

9.30e-0619930473704e8d774b3d08a311f69137972b07015c38f6
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B MUC4 MUC5AC

9.30e-061993043c3133d0aa65338a576634def13e7f0f5c573a10
ToppCellBiopsy_Other_PF-Epithelial-MUC5B+|Biopsy_Other_PF / Sample group, Lineage and Cell type

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304afd0df242a93f176438309668a9487be1250d9ca
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBiopsy_IPF-Epithelial-MUC5AC+_High|Biopsy_IPF / Sample group, Lineage and Cell type

MUC16 FAM83D MUC5B MUC5AC

9.30e-0619930451cb306e36537a53968c55187bd87c83e1706187
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304644197ff7e3299587881dd678836262e670ed4a8
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MUC16 MUC5B MUC4 MUC5AC

9.30e-061993042a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

9.30e-06199304fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5B+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

FAM83D MUC5B MUC4 MUC5AC

9.30e-061993044ab45996e6bca406c77895a5998982b8ab1cf210
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MUC16 MUC5B MUC4 MUC5AC

9.49e-0620030485f946dd3831acf3488c87efba96689cc2667c3a
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MUC16 MUC5B MUC4 MUC5AC

9.49e-06200304292c63693eb7f435335a8cfba07aa35b72139393
ToppCellBiopsy_IPF-Epithelial-MUC5B+|Biopsy_IPF / Sample group, Lineage and Cell type

MUC16 MUC5B MUC4 MUC5AC

9.49e-06200304f0a6747f6d37ec6d261bd649ac678c39cca5e4c8
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 IGF1R HECTD1 MUC4

9.49e-06200304ecbe89ff95d046155b984c8c150e0b9e7278f839
DrugDobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

LRRN2 MUC5B DSCAM IL1R2 MUC5AC

4.05e-061853056286_UP
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC4 IL1R2 MUC5AC

5.59e-0964305DOID:4947 (is_marker_for)
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B IGF1R MUC4 MUC5AC

4.35e-0761304DOID:3587 (is_marker_for)
Diseasekeratoconjunctivitis (is_marker_for)

MUC16 MUC5AC

3.00e-063302DOID:9368 (is_marker_for)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC5AC

9.97e-065302DOID:3030 (is_marker_for)
Diseasebiliary tract benign neoplasm (is_marker_for)

MUC4 MUC5AC

2.09e-057302DOID:0050625 (is_marker_for)
Diseasecommon bile duct neoplasm (is_marker_for)

MUC4 MUC5AC

2.79e-058302DOID:4608 (is_marker_for)
Diseaseotitis media (is_marker_for)

MUC5B MUC4

4.47e-0510302DOID:10754 (is_marker_for)
Diseasedry eye syndrome (is_marker_for)

MUC16 MUC5AC

4.47e-0510302DOID:10140 (is_marker_for)
Diseasenucleus accumbens volume change measurement

MUC16 DSCAM

5.46e-0511302EFO_0021493
Diseasepulmonary fibrosis

MUC5B MUC5AC

5.46e-0511302EFO_0009448
Diseaseotitis media (biomarker_via_orthology)

MUC4 MUC5AC

1.35e-0417302DOID:10754 (biomarker_via_orthology)
Diseasepancreatic cancer (is_marker_for)

MUC16 MUC4 MUC5AC

1.48e-04101303DOID:1793 (is_marker_for)
DiseaseSjogren's syndrome (is_marker_for)

MUC16 MUC5AC

2.72e-0424302DOID:12894 (is_marker_for)
Diseaselysophosphatidylethanolamine 16:0 measurement

ANKRD17 TNR

3.20e-0426302EFO_0010366
DiseaseCOVID-19 symptoms measurement

MUC5B MUC5AC

5.82e-0435302EFO_0600019
Diseasetuberculosis

SLC8A3 DSCAM TNR

1.36e-03216303MONDO_0018076
Diseaseidiopathic pulmonary fibrosis

MUC5B MUC5AC

1.54e-0357302EFO_0000768
Diseaseresponse to opioid

MUC16 TNR

1.76e-0361302EFO_0008541
Diseasecystic fibrosis (is_marker_for)

MUC5B MUC5AC

1.82e-0362302DOID:1485 (is_marker_for)
Diseaseinterstitial lung disease

MUC5B MUC5AC

2.12e-0367302EFO_0004244
DiseaseAlzheimer's disease (is_marker_for)

MRE11 SLC8A3 IGF1R

2.23e-03257303DOID:10652 (is_marker_for)
Diseaseurinary bladder cancer (is_implicated_in)

MRE11 MUC5B

2.72e-0376302DOID:11054 (is_implicated_in)
Diseaselung adenocarcinoma (is_marker_for)

MUC4 IL1R2

3.39e-0385302DOID:3910 (is_marker_for)
Diseasefeeling nervous measurement

ZCCHC14 DSCAM

3.54e-0387302EFO_0009597
DiseaseInhalant adrenergic use measurement

MUC16 MUC5AC

4.29e-0396302EFO_0009941
Diseasechronic obstructive pulmonary disease (is_marker_for)

MUC5B MUC5AC

4.38e-0397302DOID:3083 (is_marker_for)
Diseasesusceptibility to pneumonia measurement

MUC5B MUC5AC

4.38e-0397302EFO_0008410
DiseaseAbortion, Tubal

TNR MUC4

5.50e-03109302C0000822
DiseaseEarly Pregnancy Loss

TNR MUC4

5.50e-03109302C3830362
DiseaseMiscarriage

TNR MUC4

5.50e-03109302C4552766
DiseaseSpontaneous abortion

TNR MUC4

5.50e-03109302C0000786
Diseasepancreatic cancer (is_implicated_in)

IGF1R MUC4

5.79e-03112302DOID:1793 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
DKTNSLIWTTRTTRT

CATSPERG

976

Q6ZRH7
TKVWSLTSSSARTSN

ADGRD1

821

Q6QNK2
ATTTTTIGISATWTT

ANKRD17

1536

O75179
SSLGTTWTRLSQTTT

MUC5B

1986

Q9HC84
WILTKLTTTATTTES

MUC5B

3691

Q9HC84
TTWILTELTTTATTT

MUC5B

4246

Q9HC84
LRATTSSTSKASSWT

MUC16

506

Q8WXI7
SQGTLTWDTSITTSQ

MUC16

6456

Q8WXI7
TTSWRTSIQDTSASS

MUC4

181

Q99102
TVSTNLTWSSASSLR

LRRN2

551

O75325
TSTTTSKNRIIITWH

IGF1R

496

P08069
TRIASSQTTIWSRST

FAM83D

426

Q9H4H8
SQTTIWSRSTTTQTD

FAM83D

431

Q9H4H8
TQSTSSWQKSRTTTL

MUC5AC

2241

P98088
SWQKSRTTTLVTTST

MUC5AC

2246

P98088
PTQSTSSWQKSRTTT

MUC5AC

3346

P98088
SSWQKSRTTTLVTTS

MUC5AC

3351

P98088
QSTSSWQKSRTTTLV

MUC5AC

3646

P98088
WQKSRTTTLVTSSIT

MUC5AC

3651

P98088
SPTQSTSSWQKSRTT

MUC5AC

4076

P98088
TSSWQKSRTTTLVTT

MUC5AC

4081

P98088
ISCTTSTTWSRLQTQ

FAAP100

506

Q0VG06
SSSTLTQNEISSVWK

PTPRQ

291

Q9UMZ3
KTWQADTSTTLSSIR

PARP14

381

Q460N5
SSMTTTWRLSSTTTT

PILRA

161

Q9UKJ1
STVSGTTQSWSSLVK

HECTD1

1351

Q9ULT8
SSWLSTFTTSTSQSL

AVL9

626

Q8NBF6
EKISWTTKSRTSYSS

CCDC168

6901

Q8NDH2
TSQTSWTSSSTKRNA

nan

66

A6NNC1
TVSKTTSSSITLSWL

DSCAM

1386

O60469
SQVSALSWSQETTKT

SPATA31C2

281

B4DYI2
INSSITTKAISRWSS

CCT3

156

P49368
WSSTSSSKIMSQSQV

MRE11

666

P49959
TLRTTVKEASSTFSW

IL1R2

336

P27930
MSTERTSWTSLSTIQ

TDRKH

1

Q9Y2W6
ASSETSISLIWTKAS

TNR

696

Q92752
TRISSAGNTQTTWTT

USF3

421

Q68DE3
KLTITQAVTTTTTWR

PILRB

146

Q9UKJ0
LWSDSSITSVTKSSS

ZCCHC14

121

Q8WYQ9
VSTSRQTWVATNTLS

ZSWIM8

821

A7E2V4
SIRSSQWSFSTISSS

TMEM134

86

Q9H6X4
TSTTTIRVWNETVSN

SLC8A3

121

P57103