Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK9 CDK16 CDK17 CDK18 CDK15 CDK14 CDK13	2.16e-09	30	151	7	GO:0004693
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK9 CDK16 CDK17 CDK18 CDK15 CDK14 CDK13	2.16e-09	30	151	7	GO:0097472
GeneOntologyMolecularFunction	protein serine kinase activity	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 CDK13 CLK3 MAPK4	2.11e-05	363	151	12	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 IKBKE CDK13 CLK3 MAPK4	3.55e-05	446	151	13	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4 PCK1	5.15e-05	600	151	15	GO:0004672
GeneOntologyMolecularFunction	NADH oxidase H202-forming activity	DUOX2 DUOX1	5.68e-05	2	151	2	GO:0106293
GeneOntologyMolecularFunction	efflux transmembrane transporter activity	ABCB6 SLC22A2 SLC26A6	2.21e-04	16	151	3	GO:0015562
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4 PCK1	3.20e-04	709	151	15	GO:0016773
GeneOntologyMolecularFunction	acetylglucosaminyltransferase activity	HEXB B4GAT1 MGAT1 A4GALT	4.35e-04	47	151	4	GO:0008375
GeneOntologyMolecularFunction	ubiquitin-specific protease binding	AMFR DERL1 CLTC	4.40e-04	20	151	3	GO:1990381
GeneOntologyMolecularFunction	NADPH oxidase H202-forming activity	DUOX2 DUOX1	5.60e-04	5	151	2	GO:0106294
GeneOntologyMolecularFunction	kinase activity	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4 PCK1	6.95e-04	764	151	15	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK9 CDK16 CDK17 SMG1 CDK18 PGS1 CDK15 PAK4 MAP3K14 CDK14 MST1R RPAP1 IKBKE CDK13 CLK3 MAPK4 PCK1	7.50e-04	938	151	17	GO:0016772
GeneOntologyMolecularFunction	heme binding	PTGES2 DUOX2 ABCB6 CYP46A1 DUOX1 CYP26C1	1.13e-03	154	151	6	GO:0020037
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	ABCC6 SLC22A2 SLC26A6 ABCC10	1.17e-03	61	151	4	GO:1901682
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC6 ABCC10	1.54e-03	8	151	2	GO:0015431
GeneOntologyMolecularFunction	tetrapyrrole binding	PTGES2 DUOX2 ABCB6 CYP46A1 DUOX1 CYP26C1	1.57e-03	164	151	6	GO:0046906
GeneOntologyBiologicalProcess	regulation of Rab protein signal transduction	DENND4A DENND4C MADD	6.98e-06	6	147	3	GO:0032483
Domain	Protein_kinase_ATP_BS	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4	1.12e-05	379	149	13	IPR017441
Domain	Ser/Thr_kinase_AS	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 IKBKE CDK13 CLK3 MAPK4	3.00e-05	357	149	12	IPR008271
Domain	S_TKc	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 IKBKE CDK13 CLK3 MAPK4	3.17e-05	359	149	12	SM00220
Domain	PROTEIN_KINASE_ST	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 IKBKE CDK13 CLK3 MAPK4	3.44e-05	362	149	12	PS00108
Domain	Pkinase	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 IKBKE CDK13 CLK3 MAPK4	5.64e-05	381	149	12	PF00069
Domain	DUOX1	DUOX2 DUOX1	6.32e-05	2	149	2	IPR029595
Domain	PROTEIN_KINASE_ATP	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4	8.11e-05	459	149	13	PS00107
Domain	Kinase-like_dom	CDK9 CDK16 CDK17 SMG1 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4	1.14e-04	542	149	14	IPR011009
Domain	Prot_kinase_dom	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4	1.52e-04	489	149	13	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK9 CDK16 CDK17 CDK18 CDK15 PAK4 MAP3K14 CDK14 MST1R IKBKE CDK13 CLK3 MAPK4	1.65e-04	493	149	13	PS50011
Domain	DENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	SM00799
Domain	DENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	PF02141
Domain	dDENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	PF03455
Domain	UDENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	PS50946
Domain	DDENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	PS50947
Domain	dDENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	SM00801
Domain	dDENN_dom	DENND4A DENND4C MADD	2.58e-04	16	149	3	IPR005112
Domain	uDENN_dom	DENND4A DENND4C MADD	2.58e-04	16	149	3	IPR005113
Domain	DENN	DENND4A DENND4C MADD	2.58e-04	16	149	3	PS50211
Domain	DENN_dom	DENND4A DENND4C MADD	2.58e-04	16	149	3	IPR001194
Domain	fn3	IL11RA COL7A1 FN1 DSCAM TNC PTPRO TNXB	3.25e-04	162	149	7	PF00041
Domain	PPR	DENND4A DENND4C	3.75e-04	4	149	2	PF01535
Domain	GPR40-rel_orph	FFAR3 GPR42	3.75e-04	4	149	2	IPR013312
Domain	FN3	IL11RA COL7A1 FN1 DSCAM TNC PTPRO TNXB	7.18e-04	185	149	7	SM00060
Domain	ABC_membrane	ABCB6 ABCC6 ABCC10	8.91e-04	24	149	3	PF00664
Domain	FN3	IL11RA COL7A1 FN1 DSCAM TNC PTPRO TNXB	1.10e-03	199	149	7	PS50853
Domain	EGF-like_CS	NID2 FN1 TNC PGAP6 FAT1 NRXN2 TNXB MASP2	1.20e-03	261	149	8	IPR013032
Domain	NAD_binding_6	DUOX2 DUOX1	1.29e-03	7	149	2	PF08030
Domain	FAD_binding_8	DUOX2 DUOX1	1.29e-03	7	149	2	PF08022
Domain	FAD-bd_8	DUOX2 DUOX1	1.29e-03	7	149	2	IPR013112
Domain	Fe_red_NAD-bd_6	DUOX2 DUOX1	1.29e-03	7	149	2	IPR013121
Domain	ABC_TM1F	ABCB6 ABCC6 ABCC10	1.41e-03	28	149	3	PS50929
Domain	ABC1_TM_dom	ABCB6 ABCC6 ABCC10	1.41e-03	28	149	3	IPR011527
Domain	FN3_dom	IL11RA COL7A1 FN1 DSCAM TNC PTPRO TNXB	1.46e-03	209	149	7	IPR003961
Domain	PPR	DENND4A DENND4C	1.72e-03	8	149	2	PS51375
Pubmed	Cyclin-dependent kinases: a family portrait.	CDK16 CDK17 CDK18 CDK15 CDK14 CDK13	5.94e-12	12	153	6	19884882
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	NID2 COL7A1 FN1 TNC APOL4 ADAMTS20 TNXB	1.40e-08	64	153	7	22261194
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK9 CDK16 CDK17 CDK18 NES DENND4A PAK4 MAP3K14 PARD3B TBC1D22B CDK14 DENND4C MADD IKBKE CLK3 OSBPL10 MIEF1 MAPK4	5.23e-08	861	153	18	36931259
Pubmed	Expression of tenascin in developing and adult mouse lymphoid organs.	FN1 TNC TNXB	8.35e-08	3	153	3	7687262
Pubmed	PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.	CDK16 CDK17 CDK18	3.33e-07	4	153	3	1437147
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	CDK9 CDK16 CDK17 CDK18 PAK4 CLK3	1.30e-06	78	153	6	17192257
Pubmed	The Role of CDKs and CDKIs in Murine Development.	CDK9 CDK16 CDK17 CDK13	2.03e-06	21	153	4	32731332
Pubmed	Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.	FN1 TNC ACAN TNXB	2.48e-06	22	153	4	27527664
Pubmed	A family of human cdc2-related protein kinases.	CDK16 CDK17 CDK18	4.60e-06	8	153	3	1639063
Pubmed	Mice develop normally without tenascin.	FN1 TNC TNXB	4.60e-06	8	153	3	1383086
Pubmed	SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors.	NID2 FN1 TNC	4.60e-06	8	153	3	21349332
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CDK9 CDK18 CDK15 MAP3K14 CDK14 AREL1 IKBKE CLK3 KLHL34 MAPK4	6.43e-06	372	153	10	22939624
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 DMXL2 PGS1 DENND4A ACADM DHX37 MADD RPAP1 CDK13 TONSL EIF2B5 OSBPL10 OGFOD1	6.61e-06	650	153	13	38777146
Pubmed	Dynamic expression patterns of ECM molecules in the developing mouse olfactory pathway.	NES TNC ACAN	6.88e-06	9	153	3	18570250
Pubmed	Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.	FN1 ADAMTS5 ACAN	1.34e-05	11	153	3	38750698
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	CDK17 DENND4A PAK4 PARD3B CLK3 PIK3R2 CLTC MIEF1	1.85e-05	255	153	8	15324660
Pubmed	Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.	DUOX2 DUOX1	1.92e-05	2	153	2	28633507
Pubmed	Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.	FFAR3 GPR42	1.92e-05	2	153	2	25637492
Pubmed	ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.	ZDHHC11B ZDHHC11	1.92e-05	2	153	2	28331227
Pubmed	Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.	FFAR3 GPR42	1.92e-05	2	153	2	30478340
Pubmed	Type VII collagen specifically binds fibronectin via a unique subdomain within the collagenous triple helix.	COL7A1 FN1	1.92e-05	2	153	2	7963647
Pubmed	The tenascin gene family in axon growth and guidance.	TNC TNXB	1.92e-05	2	153	2	9321695
Pubmed	Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.	FFAR3 GPR42	1.92e-05	2	153	2	35858247
Pubmed	Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.	FFAR3 GPR42	1.92e-05	2	153	2	22506074
Pubmed	Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.	DUOX2 DUOX1	1.92e-05	2	153	2	22523549
Pubmed	GRIM-19 associates with the serine protease HtrA2 for promoting cell death.	HTRA2 NDUFA13	1.92e-05	2	153	2	17297443
Pubmed	Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.	DUOX2 DUOX1	1.92e-05	2	153	2	23281318
Pubmed	Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.	DUOX2 DUOX1	1.92e-05	2	153	2	31706280
Pubmed	The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.	FFAR3 GPR42	1.92e-05	2	153	2	24748202
Pubmed	Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage.	FN1 ACAN	1.92e-05	2	153	2	21224775
Pubmed	Staphylococcal superantigen-like protein 8 (SSL8) binds to tenascin C and inhibits tenascin C-fibronectin interaction and cell motility of keratinocytes.	FN1 TNC	1.92e-05	2	153	2	23485472
Pubmed	The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.	FFAR3 GPR42	1.92e-05	2	153	2	36362376
Pubmed	Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.	FN1 TNC	1.92e-05	2	153	2	28986537
Pubmed	Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.	FFAR3 GPR42	1.92e-05	2	153	2	20399779
Pubmed	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.	DUOX2 DUOX1	1.92e-05	2	153	2	15972824
Pubmed	Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.	DUOX2 DUOX1	1.92e-05	2	153	2	23362256
Pubmed	Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.	DUOX2 DUOX1	1.92e-05	2	153	2	19144650
Pubmed	Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.	FFAR3 GPR42	1.92e-05	2	153	2	23110765
Pubmed	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	FFAR3 GPR42	1.92e-05	2	153	2	26522986
Pubmed	Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.	FFAR3 GPR42	1.92e-05	2	153	2	27664183
Pubmed	Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.	TNC TNXB	1.92e-05	2	153	2	17202312
Pubmed	Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.	DUOX2 DUOX1	1.92e-05	2	153	2	11762710
Pubmed	Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.	DUOX2 DUOX1	1.92e-05	2	153	2	11822874
Pubmed	Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes.	TNC ACAN	1.92e-05	2	153	2	7524681
Pubmed	Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.	FN1 TNC	1.92e-05	2	153	2	23313574
Pubmed	Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.	DUOX2 DUOX1	1.92e-05	2	153	2	18177232
Pubmed	Cryptic domains of tenascin-C differentially control fibronectin fibrillogenesis.	FN1 TNC	1.92e-05	2	153	2	20708078
Pubmed	Distribution of tenascin-C and -X, and soft X-ray analysis of the mandibular symphysis during mandible formation in the human fetus.	TNC TNXB	1.92e-05	2	153	2	15455729
Pubmed	Tenascin variants: ligands and expression.	TNC TNXB	1.92e-05	2	153	2	7509489
Pubmed	Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.	ZDHHC11B ZDHHC11	1.92e-05	2	153	2	35384384
Pubmed	G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.	FFAR3 GPR42	1.92e-05	2	153	2	37019194
Pubmed	The effects of tenascin C knockdown on trabecular meshwork outflow resistance.	TNC TNXB	1.92e-05	2	153	2	23882691
Pubmed	Binding of tenascin-C to soluble fibronectin and matrix fibrils.	FN1 TNC	1.92e-05	2	153	2	7499434
Pubmed	Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.	DUOX2 DUOX1	1.92e-05	2	153	2	12824283
Pubmed	3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.	FFAR3 GPR42	1.92e-05	2	153	2	38040866
Pubmed	Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.	DUOX2 DUOX1	1.92e-05	2	153	2	30375286
Pubmed	Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.	FFAR3 GPR42	1.92e-05	2	153	2	35408893
Pubmed	FFAR3 modulates insulin secretion and global gene expression in mouse islets.	FFAR3 GPR42	1.92e-05	2	153	2	26091414
Pubmed	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.	DUOX2 DUOX1	1.92e-05	2	153	2	10806195
Pubmed	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.	DUOX2 DUOX1	1.92e-05	2	153	2	11514595
Pubmed	GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.	FFAR3 GPR42	1.92e-05	2	153	2	27550964
Pubmed	Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes.	CDK16 CDK18	1.92e-05	2	153	2	8088790
Pubmed	Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5.	ADAMTS5 ACAN	1.92e-05	2	153	2	21928430
Pubmed	Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.	CDK17 CDK18	1.92e-05	2	153	2	26885753
Pubmed	Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.	DUOX2 DUOX1	1.92e-05	2	153	2	24161126
Pubmed	Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.	FFAR3 GPR42	1.92e-05	2	153	2	32073900
Pubmed	Tenascin C, Fibronectin, and Tumor-Stroma Ratio in Pancreatic Ductal Adenocarcinoma.	FN1 TNC	1.92e-05	2	153	2	30451798
Pubmed	Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts.	TNC TNXB	1.92e-05	2	153	2	8856503
Pubmed	Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.	DUOX2 DUOX1	1.92e-05	2	153	2	11443211
Pubmed	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.	DUOX2 DUOX1	1.92e-05	2	153	2	10601291
Pubmed	Cleft palate formation in fetal Br mice with midfacial retrusion: tenascin, fibronectin, laminin, and type IV collagen immunolocalization.	FN1 TNC	1.92e-05	2	153	2	9482226
Pubmed	Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.	FFAR3 GPR42	1.92e-05	2	153	2	19630535
Pubmed	The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.	DUOX2 DUOX1	1.92e-05	2	153	2	25586178
Pubmed	De novo expression of fetal ED-A(+) fibronectin and B (+) tenascin-C splicing variants in human cardiac allografts: potential impact for targeted therapy of rejection.	FN1 TNC	1.92e-05	2	153	2	24792713
Pubmed	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.	DUOX2 DUOX1	1.92e-05	2	153	2	16111680
Pubmed	Invasion of melanoma in double knockout mice lacking tenascin-X and tenascin-C.	TNC TNXB	1.92e-05	2	153	2	12359049
Pubmed	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.	FFAR3 GPR42	1.92e-05	2	153	2	14722361
Pubmed	Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.	DUOX2 DUOX1	1.92e-05	2	153	2	11753072
Pubmed	Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.	DUOX2 DUOX1	1.92e-05	2	153	2	18281478
Pubmed	Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.	DUOX2 DUOX1	1.92e-05	2	153	2	15062544
Pubmed	Regulated hydrogen peroxide production by Duox in human airway epithelial cells.	DUOX2 DUOX1	1.92e-05	2	153	2	15677770
Pubmed	The change in tenascin expression in mouse uterus during early pregnancy.	TNC TNXB	1.92e-05	2	153	2	9013311
Pubmed	Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.	DUOX2 DUOX1	1.92e-05	2	153	2	24128054
Pubmed	Changes in extra cellular matrix remodelling and re-expression of fibronectin and tenascin-C splicing variants in human myocardial tissue of the right atrial auricle: implications for a targeted therapy of cardiovascular diseases using human SIP format antibodies.	FN1 TNC	1.92e-05	2	153	2	20232238
Pubmed	Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.	FFAR3 GPR42	1.92e-05	2	153	2	26260360
Pubmed	Transcriptome analysis of human gastric cancer.	MAGEA6 CDK18 PTGES2 TMC4 CDK14 NDUFA13 TGIF1 DBNDD1 KRTCAP3 HCFC1R1 HYI PRDM15 PCK1	3.99e-05	772	153	13	16341674
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	NID2 FN1 TNC SERPINE2 TNXB	4.03e-05	86	153	5	28327460
Pubmed	Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.	HEXB RPGRIP1 BCAT2 ACAN	4.26e-05	44	153	4	27534441
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	CDK18 PTGES2 PGS1 ACADM HTRA2 FPGS ABCB6 BCAT2 LARS2 DARS2 COQ10A NDUFA13 MRPS7 NUDT6 MIEF1 CA5B	4.39e-05	1136	153	16	34800366
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	ABCC6 SLC22A2 ABCC10	4.48e-05	16	153	3	35307651
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	DMXL2 OTUD1 DARS2 MRPS7 GTF2I WDHD1	4.98e-05	147	153	6	29576527
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CDK17 MAGEA6 AMFR DENND4A QPCTL CDK15 DHX37 PAK4 CDK14 MRPS7 TGIF1 GTF2I IKBKE CLK3 TONSL EIF2B5 CLTC	5.40e-05	1284	153	17	17353931
Pubmed	A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.	AMFR DERL1	5.75e-05	3	153	2	29275994
Pubmed	Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.	DENND4A DENND4C	5.75e-05	3	153	2	12906859
Pubmed	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.	FFAR3 GPR42	5.75e-05	3	153	2	12496283
Pubmed	Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.	TNC TNXB	5.75e-05	3	153	2	7694605
Pubmed	PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport.	CDK16 CDK18	5.75e-05	3	153	2	16091426
Pubmed	Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.	FFAR3 GPR42	5.75e-05	3	153	2	23665276
Pubmed	Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.	FFAR3 GPR42	5.75e-05	3	153	2	34210970
Pubmed	TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation.	CDK9 GTF2I	5.75e-05	3	153	2	36690785
Cytoband	16p13.3	PRSS41 PAQR4 RHBDL1 PGAP6 JMJD8 HCFC1R1	1.78e-04	244	153	6	16p13.3
GeneFamily	Cyclin dependent kinases	CDK9 CDK16 CDK17 CDK18 CDK15 CDK14 CDK13	7.19e-11	26	99	7	496
GeneFamily	Fibronectin type III domain containing	COL7A1 FN1 DSCAM TNC PTPRO TNXB	2.49e-04	160	99	6	555
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND4A DENND4C MADD	3.36e-04	25	99	3	504
GeneFamily	ATP binding cassette subfamily C	ABCC6 ABCC10	2.23e-03	13	99	2	807
GeneFamily	Rhomboid family	DERL1 RHBDL1	2.59e-03	14	99	2	926
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA9 CHRNG	3.39e-03	16	99	2	173
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 ACAN APOL4 SGCE	4.21e-07	197	153	8	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL11RA AMFR ZDHHC11B COQ10A ACAN TIGD5 HYI	1.07e-06	154	153	7	b944be7fc30d8897d52689f2b2622ff7ede8a6a1
ToppCell	moderate-Lymphoid-NK\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NES NID2 COL7A1 FN1 TNC SERPINE2 SGCE	3.62e-06	185	153	7	4979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL11RA NID2 FN1 TNC SERPINE2 HCFC1R1 SGCE	5.66e-06	198	153	7	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	DOK1 DENND4A TMC4 CDCP1 A4GALT DYNLT4 IL4I1	6.05e-06	200	153	7	5c638c80661017c85f9390f1b398ac7728c8f001
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 ZDHHC11B FPGS DBNDD1 WDHD1 KRTCAP3	1.67e-05	156	153	6	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	356C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZDHHC11B CDK15 PARD3B TFR2 KLHL34 TTLL10	2.22e-05	164	153	6	b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell	356C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZDHHC11B CDK15 PARD3B TFR2 KLHL34 TTLL10	2.22e-05	164	153	6	f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 ZDHHC11B FPGS DBNDD1 WDHD1 KRTCAP3	2.46e-05	167	153	6	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 ZDHHC11B FPGS DBNDD1 WDHD1 KRTCAP3	2.72e-05	170	153	6	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 DIPK1A BTBD17 MADD PTPRO SLC26A6	3.00e-05	173	153	6	3c51e7bda1835c25915e50c801b0d643979971a3
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 DIPK1A BTBD17 MADD PTPRO SLC26A6	3.00e-05	173	153	6	a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL7A1 FN1 MADD MST1R FAT1 ACAN	3.09e-05	174	153	6	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	Adult-Immune-dendritic_cell-D175\|Adult / Lineage, Cell type, age group and donor	DIPK1A MAP3K14 NRXN2 APCDD1L DISP2 IL4I1	3.30e-05	176	153	6	1f0f1f953e6d61119f342de0d980aa1287511dba
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 SERPINE2 NRXN2 APCDD1L SGCE TNXB	3.86e-05	181	153	6	e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NES NID2 COL7A1 FN1 TNC SGCE	3.98e-05	182	153	6	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NID2 FN1 TNC ADAMTS5 SERPINE2 TNXB	3.98e-05	182	153	6	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNC DUOX2 ABCB6 TBC1D22B NRXN2 OSBPL10	4.36e-05	185	153	6	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	Mesenchymal_cells-Osteo-CAR\|World / Lineage and Cell class	TNC ADAMTS5 FAT1 SERPINE2 SLC22A2 SGCE	4.36e-05	185	153	6	16f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD3 C16orf95 ADAMTS5 SERPINE2 ZDHHC11 TNXB	4.63e-05	187	153	6	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 TNC FAT1 SERPINE2 ACAN APOL4	5.20e-05	191	153	6	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	COL7A1 TNC RHBDL1 BCAT2 FAT1 A4GALT	5.20e-05	191	153	6	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 TNC FAT1 SERPINE2 ACAN APOL4	5.20e-05	191	153	6	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NID2 FN1 TNC CDK14 SERPINE2 TNXB	5.36e-05	192	153	6	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP6 DENND4C MADD CLTC LRP3 DISP2	5.51e-05	193	153	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 APOL4	5.51e-05	193	153	6	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP6 DENND4C MADD CLTC LRP3 DISP2	5.51e-05	193	153	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA FN1 ADAMTS5 SERPINE2 IAH1 TNXB	5.51e-05	193	153	6	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 COL7A1 TNC PARD3B FAT1 PTPRO	5.67e-05	194	153	6	43eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ACADM RHBDL1 PARD3B CDK14 METTL25B PTPRO	5.84e-05	195	153	6	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL11RA NID2 SERPINE2 NRXN2 SGCE TNXB	6.18e-05	197	153	6	2744cc94883c5d0424677cf5093bbab622933e9b
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 ACAN SGCE	6.35e-05	198	153	6	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 APOL4	6.35e-05	198	153	6	6a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 ACAN	6.35e-05	198	153	6	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	facs-Trachea-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA FN1 ADAMTS5 SERPINE2 SGCE TNXB	6.35e-05	198	153	6	e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 ACAN	6.53e-05	199	153	6	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IL11RA FN1 TNC ADAMTS5 FAT1 TNXB	6.53e-05	199	153	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	(5)_Epi_suprabasal\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	COL7A1 TNC BCAT2 TGIF1 SERPINE2 KRTCAP3	6.53e-05	199	153	6	e1d0fd71b2f3925d02638413f2155db009f103d9
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 TNC ADAMTS5 SERPINE2 SGCE TNXB	6.53e-05	199	153	6	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NID2 FN1 TNC CDK14 LRP3 TNXB	6.53e-05	199	153	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NES FN1 TNC FAT1 SERPINE2 ACAN	6.53e-05	199	153	6	bf138cc692df727e087d140c014149ee5da00d9d
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HEXB FN1 PAQR4 TRIM14 WDHD1 APOL4	6.71e-05	200	153	6	0cf7208eab0dc58fbea35e256c5cb55cdd4a4928
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-4\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	IL11RA FN1 SERPINE2 APCDD1L SGCE TNXB	6.71e-05	200	153	6	54b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCell	(5)_Epithelial_cells-(5)_Epi_suprabasal\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	COL7A1 TNC BCAT2 TGIF1 SERPINE2 KRTCAP3	6.71e-05	200	153	6	92382ca82da3e435ccbee1c73261d55164d54779
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 TNC RHBDL1 GSDMC FAT1 KRTCAP3	6.71e-05	200	153	6	0594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_2\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DUOX2 HOXB9 DBNDD1 APOL4 IL4I1	7.75e-05	127	153	5	508b188ccbe5aa6ec0128c443aedb5a8ea35a6d0
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DUOX2 HOXB9 DBNDD1 APOL4 IL4I1	8.66e-05	130	153	5	04ad0542210e7a8c8d4d9d0bfd83de2629bc3176
Computational	Neighborhood of CASP2	DENND4A DHX37 TBC1D22B COQ10A	3.97e-05	27	78	4	GCM_CASP2
Computational	Neighborhood of TINF2	DENND4A DHX37 TBC1D22B COQ10A	2.12e-04	41	78	4	GCM_TINF2
Drug	NSC105327	CDK9 CDK16 CDK17 CDK18 CDK14 CDK13 TONSL	4.15e-07	70	151	7	CID005318433
Disease	lissencephaly (implicated_via_orthology)	CDK17 CDK18 CDK15 CDK14	8.28e-06	27	142	4	DOID:0050453 (implicated_via_orthology)
Disease	lean body mass	AMPD3 PARD3B DCST2 MST1R NUDT6 ACAN SLC22A2 FGF3 MASP2	9.64e-05	379	142	9	EFO_0004995
Disease	hemifacial microsomia	NID2 PARD3B FGF3	9.99e-05	19	142	3	MONDO_0015398
Disease	phenylketonuria (implicated_via_orthology)	DUOX2 DUOX1	1.37e-04	4	142	2	DOID:9281 (implicated_via_orthology)
Disease	bowel opening frequency	CDK18 FFAR3 GPR42	4.03e-04	30	142	3	EFO_0600084
Disease	Colorectal Neoplasms	COL7A1 FPGS SLC22A15 ABCB6 ABCC6 FAT1 CDH22	4.03e-04	277	142	7	C0009404
Disease	Colorectal Carcinoma	MKRN3 COL7A1 FN1 FPGS SLC22A15 ABCB6 ABCC6 FAT1 CDH22 RPAP1 TTLL10	6.10e-04	702	142	11	C0009402
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX2 DUOX1	8.10e-04	9	142	2	DOID:0050338 (implicated_via_orthology)
Disease	tenascin measurement	TNC TNXB	1.01e-03	10	142	2	EFO_0008296
Disease	degenerative disc disease (biomarker_via_orthology)	ADAMTS5 ACAN	1.23e-03	11	142	2	DOID:90 (biomarker_via_orthology)
Disease	hypothyroidism (implicated_via_orthology)	DUOX2 DUOX1	1.73e-03	13	142	2	DOID:1459 (implicated_via_orthology)
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX2 DUOX1	2.01e-03	14	142	2	DOID:0050328 (implicated_via_orthology)
Disease	phenylalanine measurement	LARS2 ABCC6 WDHD1	2.38e-03	55	142	3	EFO_0005001
Disease	transferrin saturation measurement	DUOX2 TFR2	2.64e-03	16	142	2	EFO_0006333
Disease	fibroblast growth factor basic measurement	PCNX3 SERPINE2 ACAN	2.91e-03	59	142	3	EFO_0008130
Disease	acute kidney failure (biomarker_via_orthology)	NES FN1 SLC22A2	3.20e-03	61	142	3	DOID:3021 (biomarker_via_orthology)
Disease	hearing loss	NID2 ACAN IL4I1	4.17e-03	67	142	3	EFO_0004238
Disease	osteoarthritis (biomarker_via_orthology)	ADAMTS5 ACAN	4.55e-03	21	142	2	DOID:8398 (biomarker_via_orthology)
Disease	Infiltrating duct carcinoma of female breast	SMG1 CDK15	4.55e-03	21	142	2	C3165106
Disease	disease	BCAT2 SLC22A2	4.55e-03	21	142	2	EFO_0000408
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	COL7A1 AMPD3 BCAT2 MADD CDH22 MAPK4	4.71e-03	321	142	6	EFO_0004612, EFO_0004639

Protein segments in the cluster

Peptide	Gene	Start	Entry
PINIRWRDSVYDPGL	CA5B	66	Q9Y2D0
WRDSVYDPGLKPLTI	CA5B	71	Q9Y2D0
WEPYLLPVLSDASRI	A4GALT	166	Q9NPC4
YSRWVNLPEESLLRP	B4GAT1	301	O43505
TVGRPLIAWRYVPIN	APOL4	256	Q9BPW4
VVTLWYRPPDVLLGS	CDK18	301	Q07002
KVYLRTPNWDRGLPS	CDCP1	556	Q9H5V8
ARYTLKPLLRGPWAE	ADAMTS5	161	Q9UNA0
PRDYEGLWVLRVPST	CHRNG	91	P07510
RSILEPNFRYPWSIP	GSDMC	431	Q9BYG8
SPRWLPVSLRPVYAD	BTBD17	361	A6NE02
RLPPARAWLPGALYE	APCDD1L	161	Q8NCL9
RHYRPPEVILELGWA	CLK3	486	P49761
LRLLSGYLWPRGSPA	ABCB6	246	Q9NP58
RIPSDLVWRPDIVLY	CHRNA9	106	Q9UGM1
IYSELILWRVDPIGP	DMXL2	721	Q8TDJ6
ILWRVDPIGPLSYTG	DMXL2	726	Q8TDJ6
EVVTLWYRPPDVLLG	CDK14	291	O94921
GEYPVPLIRRAWELG	ACADM	71	P11310
WLALRETVYDPSLPA	DISP2	1341	A7MBM2
TLWYRPPELLLGEER	CDK13	876	Q14004
LAFSRRGLPTITPLW	ASTL	241	Q6HA08
DISGIPSNVRWLPRY	ADAMTS20	631	P59510
SEPRLSIYGRSPEEW	AMPD3	436	Q01432
VWYFRRLDLPSNLPG	DENND4A	1676	Q7Z401
RRPAGVPLVYEALSW	PCK1	436	P35558
GQLDPQRLWSTYLRP	QPCTL	86	Q9NXS2
PWTTRLREIYSAPTG	DUOX1	1341	Q9NRD9
PRVYTLRIRASDWGL	FAT1	531	Q14517
GRRIAFILYLVPPWD	OGFOD1	161	Q8N543
PDYILPCSPGWRLRL	ABCC10	56	Q5T3U5
ARPSEYDLLWVPGRG	PARD3B	1051	Q8TEW8
YLGPEDSLRPSIWLS	OTUD1	411	Q5VV17
VESVPGYPRRLRASW	IL11RA	226	Q14626
PGADQWTRLRPLPYD	KLHL34	546	Q8N239
EIEAWIYRLLRSPVP	MADD	246	Q8WXG6
GPRISYPLLHEWALR	MAGEA6	296	P43360
GRRVHLAPPLTWEGY	MGAT1	426	P26572
LPLAPARWVAPSYRT	DYNLT4	96	Q5JR98
RYPVSLSSDLEWRPD	MAPK4	356	P31152
GVFLLPAPYWAPRER	FDPS	11	P14324
WLGSLRRPSLVHGYP	FDPS	26	P14324
RPTLPYRTWEAALRQ	KIAA2026	361	Q5HYC2
YTIDWSREPLPGLTR	LENG8	331	Q96PV6
PGARRQPSAERLWYV	FGF3	141	P11487
RRENGPLEWSYTLPI	IKBKE	251	Q14164
VGPWTTRLREIYSSP	DUOX2	1336	Q9NRD8
LLVYVRSWRKAGPLP	FCRL6	326	Q6DN72
ADVIRRWVYPLTPEA	EIF2B5	311	Q13144
LPGRWTSVRYERLAL	PCNX3	766	Q9H6A9
PLRYTTVLTWPVVGR	OR52B2	131	Q96RD2
TLWLREGPSRLPGYA	NUDT6	126	P53370
GDRRPAPDTWIYPLI	PGS1	341	Q32NB8
WVPPLIGELYGLRTT	NDUFA13	116	Q9P0J0
LPPEVWTAALRAGYV	NRXN2	641	Q9P2S2
STPQFLYRWLPSRRG	DERL1	201	Q9BUN8
LGFYLRSPTSPRWDP	NES	1301	P48681
TERRGVIYSPAWPLN	LRP3	51	O75074
ILIARSSPPWFIVDR	SERPINE2	361	P07093
WVAGLPGYELPYRLR	METTL25B	301	Q96FB5
TLWYRPPDVLLGSSE	CDK17	351	Q00537
WPAIGSLLDYVIRPA	MIEF1	276	Q9NQG6
WSRRANLIIPYPETD	PGAP6	451	Q9HCN3
SVAHPLWYKTRPRLG	GPR42	116	O15529
REPGERPSPIYWDTI	DQX1	226	Q8TE96
SSLPLLLPYWRDVAE	IAH1	221	Q2TAA2
CRPWLRPAALVGYTV	PAQR4	141	Q8N4S7
WLADGSLRYPIVTPR	ACAN	626	P16112
LGPTAVVLSWTRPYL	PTPRO	541	Q16827
GELTSRPTPWNLRAY	PRSS41	111	Q7RTY9
GVPPAESRYLRTWLE	HOXB9	86	P17482
ESRYLRTWLEPAPRG	HOXB9	91	P17482
PRAIAVDPIRGNLYW	NID2	1231	Q14112
YRPELPAPRTDWSLS	PIK3R2	146	O00459
PRPEVVSLETRYWAS	C3orf14	76	Q9HBI5
SWLFPELSGLPARVR	HYI	11	Q5T013
PRARVTYGTPSLWAR	HTRA2	46	O43464
VRWPPGLAEVVLSVY	CABIN1	501	Q9Y6J0
EPLLSWPYTLLRRYG	DOK1	196	Q99704
VTLWYRPPDALLGAT	CDK15	261	Q96Q40
VLKESLRLYPPAWGT	CYP46A1	356	Q9Y6A2
LRLYPPAWGTFRLLE	CYP46A1	361	Q9Y6A2
EVVTLWYRPPDILLG	CDK16	321	Q00536
LPRAGYLRSPSWTRT	DBNDD1	111	Q9H9R9
RWTPPRAQITGYRLT	FN1	1016	P02751
LVSWQPPRARITGYI	FN1	2011	P02751
YLSLEGSRWPPAIRQ	C19orf71	31	A6NCJ1
ETIWRFSPGIPAYPR	COQ10A	171	Q96MF6
SVAHPLWYKTRPRLG	FFAR3	116	O14843
VWYFRRLDLPSNLPG	DENND4C	1726	Q5VZ89
IIPWRLYTFRVCPGT	AREL1	371	O15033
LVRTARWELATPAFP	CYP26C1	476	Q6V0L0
RWTLTAPPGYRLRLY	MASP2	46	O00187
PGRTQVLRRGPLTWY	FPGS	361	Q05932
LLWRYPGSLIPEALR	HCFC1R1	101	Q9NWW0
RASSYILSWRPLRGP	COL7A1	981	Q02388
GRLPVSRVEAALPYW	C16orf95	86	Q9H693
SRVEAALPYWVPLSL	C16orf95	91	Q9H693
PLNSRAISPWRYELD	IL25	81	Q9H293
YLSSWGPRFRPLAAL	CDH22	801	Q9UJ99
YILLASSWKRPEPGI	CYB561A3	216	Q8NBI2
ARRYIPPGSIFLSQW	DCST2	386	Q5T1A1
IPFRSPSWYGIPRLE	GTF2I	511	P78347
EYVDATNLTPRLWPR	HEXB	491	P07686
SVPWLLCGPRRYASS	BCAT2	16	O15382
TLWYRPPELLLGERD	CDK9	191	P50750
RASVFYRVGWPLPAI	DHX37	1036	Q8IY37
LPWVIELFIPSGFRR	DIPK1A	241	Q5T7M9
PESPRWLYSQGRLSE	SLC22A15	246	Q8IZD6
RLPLGPCRDGWVYET	SLC22A2	116	O15244
LTIDRIGRRYPWAAS	SLC22A2	396	O15244
PTRIYDTALALWIPS	KRTCAP3	156	Q53RY4
LISRLPYGPEVDIWS	PAK4	486	O96013
RIVPLYGAVREGPWV	MAP3K14	451	Q99558
PPPREGALLLASYTW	IL4I1	386	Q96RQ9
IPPVTLRWYLATGEE	DSCAM	51	O60469
LRGNVSSYIRWPVPI	RTL5	46	Q5HYW3
RLTGPALQWVIPYIR	RTL8A	71	Q9BWD3
RPIRRTTQPIWGSLY	DARS2	16	Q6PI48
LPGLTQVRWSRYSPE	MRPS7	26	Q9Y2R9
LPPIVRGGAIDRYWP	SMS	111	P52788
RKGELTPLPETGYWR	TRIM39	416	Q9HCM9
TPLPETGYWRVRLWN	TRIM39	421	Q9HCM9
WGVRYLRPDAVPSIF	THAP8	71	Q8NA92
LRSRWLGTQPSPYAV	RPGRIP1	811	Q96KN7
RPITWRLLSGYLPAN	TBC1D22B	216	Q9NU19
DWLISRQRYWGTPIP	LARS2	446	Q15031
GYRRPLRPKDLWSLG	ABCC6	226	O95255
LPRYPVRDWLLGDLL	SLC26A6	81	Q9BXS9
SRDIPPGTELRVWYA	PRDM15	511	P57071
TAPWRGIIPQLFSRL	SMG1	1816	Q96Q15
PWYLRVERAITEASP	PTGES2	361	Q9H7Z7
IWSLYDAGPRSIRCP	SPG21	31	Q9NZD8
AYGWPELPARTRERI	TEX45	131	Q8NA69
PDGGSRWATYLELRP	PROB1	161	E7EW31
SEVGRAVWLRFSPPL	RHBDL1	351	O75783
LPSAYARSILTIPWV	OSBPL10	591	Q9BXB5
DRPGWLRYIQRTPYS	SGCE	96	O43556
LERFPWPSLRTYTGL	AMFR	6	Q9UKV5
WGSVLLESNPYRRPL	CLTC	956	Q00610
PVCYPLGRLLDWALR	CNNM1	371	Q9NRU3
ILWGVFLISRTRPPA	SHANK2-AS3	56	Q9BTD1
RLSRGTLAYLPPAPW	TGIF1	51	Q15583
DPRIYRIEWTTPDLG	PRR22	76	Q8IZ63
VVPSRYPRWFTLGHL	ZSWIM5	786	Q9P217
PYRGRWVASAPEAPL	MKRN3	211	Q13064
ARSLPFPTVLRVWDA	TBC1D10C	261	Q8IV04
EVTSWDLPPLTDRYR	TONSL	1006	Q96HA7
GDPLPLTRKSYLAWI	WDHD1	616	O75717
AATLRYRDPGVLPWG	TMC4	46	Q7Z404
LTWTEPPVRPAGYLL	TNXB	3951	P22105
TWRPPRASVTGYLLV	TNC	1906	P24821
DINPAWYASRGIRPV	PRLH	36	P81277
LYFRTLVTGALRPRW	RPAP1	1286	Q9BWH6
LVTGALRPRWCPVLY	RPAP1	1291	Q9BWH6
PRISRVNGWSLPLHY	ZDHHC11	26	Q9H8X9
YPALRLWEGAISIPR	TRIM14	426	Q14142
PRISRVNGWSLPLHY	ZDHHC11B	26	P0C7U3
RYSPDAWLSRPLLRG	TIGD5	316	Q53EQ6
GIPPSLRGRAWQYLS	TBC1D10A	111	Q9BXI6
ALEDLPWTSPGYLRP	TTLL10	261	Q6ZVT0
PWTSPGYLRPQRVLR	TTLL10	266	Q6ZVT0
RARLWPEGTPIYLQC	WDR87	791	Q6ZQQ6
LLWELLTRGAPPYRH	MST1R	1276	Q04912
LIPWAAAGRRAAPYL	TFR2	71	Q9UP52
WPLYRAPSALRLGDR	VIP	26	P01282
VWPIPRSSLEYRASS	THEG	216	Q9P2T0
SQRWTPLPSLPGYTR	KLHL35	326	Q6PF15
TTLAWLRDTYPALPP	JMJD8	211	Q96S16