Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

6.18e-2211415220GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.63e-2112415220GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.88e-2013715220GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.68e-1719215220GO:0008234
GeneOntologyMolecularFunctionpeptidase activity

USP17L7 USP17L21 USP17L4 TMPRSS15 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 ADAM7 USP17L24 USP17L5 USP17L10 USP17L19 PREPL USP17L18 USP17L17 LNPEP USP17L6P USP17L3 ADAMTS18 MMP1 USP17L22 USP17L15 USP17L8 USP17L13

4.33e-1265415226GO:0008233
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP1B STEAP1

5.67e-0451522GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP1B STEAP1

5.67e-0451522GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP1B STEAP1

5.67e-0451522GO:0008823
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.29e-2112515220GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.32e-2014415220GO:0070646
GeneOntologyBiologicalProcesspost-translational protein modification

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 UBE3B UBR4 FN3KRP USP17L24 USP17L5 BIRC3 USP17L10 USP17L19 ASB15 DDB1 USP17L18 ARRB2 USP17L17 LNPEP DAW1 HACE1 SHPRH USP17L6P USP17L3 HERC1 MED23 USP17L22 USP17L15 USP17L8 USP17L13 LARGE1

3.51e-13107415234GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 UBE3B UBR4 USP17L24 USP17L5 BIRC3 USP17L10 USP17L19 ASB15 DDB1 USP17L18 ARRB2 USP17L17 LNPEP DAW1 HACE1 SHPRH USP17L6P USP17L3 HERC1 MED23 USP17L22 USP17L15 USP17L8 USP17L13

1.89e-12100915232GO:0070647
GeneOntologyCellularComponentendoplasmic reticulum membrane

USP17L7 USP17L21 USP17L4 CYP2B6 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 TMEM39B USP17L10 USP17L19 GRM6 RTN1 USP17L18 ACSL3 SGMS1 USP17L17 USP17L6P USP17L3 ATL2 USP17L22 USP17L15 USP17L8 USP17L13

2.41e-06129315326GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

USP17L7 USP17L21 USP17L4 CYP2B6 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 TMEM39B USP17L10 USP17L19 GRM6 RTN1 USP17L18 ACSL3 SGMS1 USP17L17 USP17L6P USP17L3 ATL2 USP17L22 USP17L15 USP17L8 USP17L13

2.62e-06129915326GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

USP17L7 USP17L21 USP17L4 CYP2B6 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 TMEM39B USP17L10 USP17L19 GRM6 RTN1 USP17L18 ACSL3 SGMS1 USP17L17 USP17L6P USP17L3 ATL2 USP17L22 USP17L15 USP17L8 USP17L13

3.86e-06132715326GO:0042175
HumanPhenoAplasia/Hypoplasia of the frontal sinuses

FLNA SMCHD1 DNAI1 ALX1

3.25e-0516624HP:0009119
HumanPhenoAplasia/Hypoplasia involving the sinuses

FLNA SMCHD1 DNAI1 ALX1

3.25e-0516624HP:0009120
DomainHABP4_PAI-RBP1

USP17L7 USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13

2.96e-281615014PF04774
DomainHABP4_PAIRBP1-bd

USP17L7 USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13

2.96e-281615014IPR006861
DomainUCH

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.47e-227115018PF00443
DomainUSP_2

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.47e-227115018PS00973
DomainUSP_3

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.94e-227215018PS50235
DomainUSP_dom

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.94e-227215018IPR028889
DomainPeptidase_C19_UCH

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.94e-227215018IPR001394
DomainUSP_CS

USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.71e-216615017IPR018200
DomainUSP_1

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

5.20e-217015017PS00972
DomainCPSF_A

DDB1 CPSF1

1.91e-0431502PF03178
DomainCleavage/polyA-sp_fac_asu_C

DDB1 CPSF1

1.91e-0431502IPR004871
PathwayREACTOME_RAS_PROCESSING

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.15e-284512019MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 BIRC3 USP17L10 USP17L19 USP17L18 ARRB2 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

8.48e-1819112021MM15289
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 BIRC3 USP17L10 USP17L19 USP17L18 ARRB2 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.51e-1522112020M27578
PathwayREACTOME_DEUBIQUITINATION

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 BIRC3 USP17L10 USP17L19 USP17L18 ARRB2 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.48e-1526212021MM15286
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 ARRB2 USP17L17 PIK3CB USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.53e-1331812021MM15278
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 BIRC3 USP17L10 USP17L19 USP17L18 ARRB2 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

7.86e-1329912020M27574
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 FN3KRP USP17L5 BIRC3 USP17L10 USP17L19 DDB1 USP17L18 ARRB2 GLB1 USP17L17 ST6GALNAC3 SHPRH USP17L6P USP17L3 ADAMTS18 C3 USP17L22 USP17L15 USP17L8 USP17L13 LARGE1

3.82e-06138912029MM15307
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 FN3KRP USP17L24 CAPZA1 USP17L5 BIRC3 USP17L10 USP17L19 ASB15 DDB1 USP17L18 ARRB2 GLB1 USP17L17 ST6GALNAC3 SHPRH USP17L3 ADAMTS18 C3 USP17L22 USP17L15 USP17L8 USP17L13 LARGE1

4.23e-06147512030M19806
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-4321154198622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-43211541914583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-43211541911468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-4321154198756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-43211541912447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.25e-43211541918980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

9.12e-4322154199154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.50e-4124154198995226
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.04e-40251541921115691
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.84e-40261541935816173
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.27e-39331542020228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542020403174
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542014699124
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542015780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542019188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542011941478
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542017109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542020388806
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542020715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-3934154209806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542020368735
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542010936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.07e-39341542021448158
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

7.15e-39351542016611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

7.15e-39351542021239494
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.16e-38291541932527007
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.60e-38361542020147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.47e-38371542020228808
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.62e-32501541931806660
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8

5.49e-1810154824207026
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8

6.00e-1712154824695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8

3.61e-1614154811793228
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8

8.92e-1519154828067227
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L7 USP17L21 USP17L4 CYP2B6 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.39e-116741542037196079
Pubmed

Human and mouse proteases: a comparative genomic approach.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8

3.01e-0981154812838346
Pubmed

DNA sequence and analysis of human chromosome 8.

USP17L7 USP17L4 USP17L1 INTS1 USP17L3 USP17L8

7.19e-0848154616421571
Pubmed

Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.

USP17L2 USP17L15 USP17L13

3.39e-074154322984479
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA NAA15 KIF1A RPS6KA1 SMCHD1 UBR4 FN3KRP FARSB SIX4 DDB1 PREPL ACSL3 PTPRO LNPEP SNX27 C3 PADI2 DHX29

3.55e-079741541828675297
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 USP17L17

1.08e-06119154728625976
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FLNA KIF1A SMCHD1 UBR4 FN3KRP CAPZA1 FARSB BIRC3 DDB1 NDUFS3 ACSL3 SARS1 CDC40 SND1 CPSF1 CC2D2A MED23 ATL2 DHX29 NIPBL

5.32e-0614251542030948266
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

USP17L7 IPPK DNAH3 USP17L12 KIF1A TOPAZ1 UBR4 INTS1 PCARE NDUFS3 SARS1 GLIPR1L2 USP17L3 CPSF1

5.51e-067361541429676528
Pubmed

Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase.

TEC PLK4

1.95e-052154211489907
Pubmed

Single-nucleotide polymorphisms in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility.

LOXL4 C3

1.95e-052154221733505
Pubmed

KCNF1 promotes lung cancer by modulating ITGB4 expression.

ITGB4 KCNF1

1.95e-052154236385523
Pubmed

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.

BRSK2 BRSK1

1.95e-052154230307479
Pubmed

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.

C3 GPNMB

1.95e-052154228446616
Pubmed

TEC kinase stabilizes PLK4 to promote liver cancer metastasis.

TEC PLK4

1.95e-052154234637843
Pubmed

Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.

STEAP1B STEAP1

1.95e-052154237209327
Pubmed

SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.

BRSK2 BRSK1

1.95e-052154216630837
Pubmed

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.

BRSK2 BRSK1

1.95e-052154218339622
Pubmed

Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.

PCDH11Y PCDH19 PCDH9

2.99e-0514154320847152
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA NAA15 KIF1A SMCHD1 UBR4 INTS1 DDB1 ACSL3 SND1 CPSF1 DDX23 NIPBL

3.69e-056531541222586326
Pubmed

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.

BRSK2 BRSK1

5.83e-053154222669945
Pubmed

Inhibition of mouse RM-1 prostate cancer and B16F10 melanoma by the fusion protein of HSP65 & STEAP1 186-193.

STEAP1B STEAP1

5.83e-053154230841425
Pubmed

Lessons from genetic knockout mice deficient in neural recognition molecules.

MPZ ATP1B2

5.83e-05315427524110
Pubmed

PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.

RPS6KA1 ITGB4

5.83e-053154226580203
Pubmed

Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins.

FLNA ARRB2

5.83e-053154216611986
Pubmed

Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.

PCDH11Y PCDH9

5.83e-053154221129452
Pubmed

Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.

STEAP1B STEAP1

5.83e-053154211479226
Pubmed

Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.

BRSK2 BRSK1

5.83e-053154220026642
Pubmed

Microtubule stabilization specifies initial neuronal polarization.

BRSK2 BRSK1

5.83e-053154218268107
Pubmed

G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.

FLNA ARRB2

5.83e-053154215687500
Pubmed

Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.

STEAP1B STEAP1

5.83e-053154219196137
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

UBR4 INTS1 PCDH19 HACE1 CC2D2A SYT4

6.46e-05153154610718198
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

FLNA USP17L1 UBR4 FN3KRP CAPZA1 FARSB USP17L5 ACSL3 AGO1 SARS1 HMCN1 SND1 CPNE4

1.05e-048441541325963833
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA NAA15 SMCHD1 UBR4 CAPZA1 FARSB DDB1 NDUFS3 ACSL3 ARRB2 CDC40 SND1 CPSF1 SNX27 DDX23 DHX29 NIPBL

1.11e-0413531541729467282
Pubmed

Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.

ABCA9 ABCA8

1.16e-044154216445568
Pubmed

CUL4A-DDB1-Rbx1 E3 ligase controls the quality of the PTS2 receptor Pex7p.

PEX7 DDB1

1.16e-044154224989250
Pubmed

Tuberous sclerosis complex proteins control axon formation.

BRSK2 BRSK1

1.16e-044154218794346
Pubmed

Mapping of synapsin II (SYN2) genes to human chromosome 3p and mouse chromosome 6 band F.

SYN2 ATP2B2

1.16e-04415427587399
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNA SMCHD1 UBR4 FARSB SARS1 SND1 SNX27 NIPBL

1.24e-04332154832786267
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

VWA3A CYP2B6 TMPRSS15 CYP11A1 UBE3B TIMMDC1 NDUFS3 AGO1 SGMS1 PIK3CB MANEAL CC2D2A HERC1 MED23 ATP2B2 UEVLD

1.34e-0412421541630973865
Pubmed

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

FLNA ARRB2

1.93e-045154217984062
Pubmed

The Steap proteins are metalloreductases.

STEAP1B STEAP1

1.93e-045154216609065
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA9 ABCA8

1.93e-045154212532264
Pubmed

Foot pad skin biopsy in mouse models of hereditary neuropathy.

MPZ ITGB4

1.93e-045154220878767
Pubmed

The response of autologous T cells to a human melanoma is dominated by mutated neoantigens.

UBR4 GPNMB

1.93e-045154216247014
Pubmed

Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.

SYN2 ATP2B2

1.93e-04515429615221
Pubmed

Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate.

STEAP1B STEAP1

1.93e-045154212429817
Pubmed

Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function.

BRSK2 BRSK1

1.93e-045154215150265
Pubmed

C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.

BRSK2 BRSK1

1.93e-045154218854318
Pubmed

ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.

ABCA8 ABCC8

1.93e-045154228468577
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

VWA3A MPZ TRPC6 ADGRL4 SEMA3D PRELID2 ADAMTS18 MMP1 PADI2 DHX29 HYDIN

2.56e-046861541129987050
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

NAA15 KIF1A SMCHD1 UBR4 FARSB AGO1 SNX27 C3 DHX29

2.83e-04475154931040226
Pubmed

LKB1 and AMPK regulate synaptic remodeling in old age.

BRSK2 BRSK1

2.89e-046154225086610
Pubmed

Mammalian SAD kinases are required for neuronal polarization.

BRSK2 BRSK1

2.89e-046154215705853
Pubmed

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.

BRSK2 BRSK1

2.89e-046154221985311
Pubmed

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex.

TRADD BIRC3

2.89e-04615428943045
Pubmed

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).

TRADD BIRC3

2.89e-046154218939944
Pubmed

SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems.

BRSK2 BRSK1

2.89e-046154224395778
Pubmed

A unified taxonomy for ciliary dyneins.

DNAI1 DAW1

2.89e-046154221953912
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

FLNA CAPZA1 BRSK2 SYN2 BRSK1

3.14e-04132154516944949
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TOPAZ1 DDB1 DNAI1 SARS1 SHPRH CPSF1 DDX23 HERC1 HYDIN

3.93e-04497154936774506
Pubmed

RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.

FLNA ARRB2

4.03e-047154227188791
Pubmed

A class of dynamin-like GTPases involved in the generation of the tubular ER network.

RTN1 ATL2

4.03e-047154219665976
Pubmed

The structural genes encoding P450scc and P450arom are closely linked on mouse chromosome 9.

CYP11A1 GLB1

4.03e-04715422792009
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA KIAA0513 UBE3B UBR4 INTS1 KDM3B LMTK2 ITGB4 SND1 NEK8 CPSF1 DEPDC5 HERC1 CABIN1

4.20e-0411051541435748872
Pubmed

Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo.

PCDH11Y PCDH19 PCDH9

5.02e-0435154325977363
Pubmed

MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.

SEMA3D ABCC8 ADAMTS18

5.02e-0435154322407321
Pubmed

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

TRADD BIRC3

5.36e-048154219815541
Cytoband4p16.1

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.29e-2079154144p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.67e-1422215414chr4p16
Cytoband8p23.1

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8

1.44e-0515415468p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8

1.47e-042341546chr8p23
GeneFamilyNon-clustered protocadherins

PCDH11Y PCDH19 PCDH9

2.46e-051289321
GeneFamilyProteases, serine|STEAP family

STEAP1B STEAP1

2.37e-0458921324
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

CPAMD8 C3

8.43e-0498921234
GeneFamilyATP binding cassette subfamily A

ABCA9 ABCA8

2.10e-0314892805
CoexpressionMADAN_DPPA4_TARGETS

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.44e-258615119MM1312
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

7.80e-2311215119MM1095
CoexpressionGERY_CEBP_TARGETS

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 C3 USP17L22 USP17L15 USP17L8 USP17L13

3.23e-2116015120MM1155
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ITGB4 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 PADI2 USP17L15 USP17L8 USP17L13

1.65e-1064715121MM981
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

USP17L7 USP17L21 TRADD USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 UBE3B USP17L5 BIRC3 USP17L10 USP17L19 USP17L18 SARS1 CDC40 USP17L17 LNPEP USP17L6P USP17L3 HERC1 USP17L22 USP17L15 USP17L8 USP17L13

5.09e-10107215126MM1031
CoexpressionBRUINS_UVC_RESPONSE_LATE

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 LMTK2 PEX7 USP17L5 USP17L10 USP17L19 ITGB4 NDUFS3 USP17L18 USP17L17 USP17L6P USP17L3 SMG9 SNX27 LRRC28 USP17L22 USP17L15 USP17L8 USP17L13

5.19e-09119815126MM1062
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

USP17L7 IPPK USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ITGB4 USP17L18 USP17L17 USP17L6P USP17L3 HERC1 USP17L22 PADI2 USP17L15 USP17L8 USP17L13

5.86e-07122615123MM979
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#1_top-relative-expression-ranked_200

KCNF1 LNPEP SYN2 C3 OSMR

1.35e-05501305gudmap_developingLowerUrinaryTract_adult_bladder_200_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_1000

MPZ BRSK2 RTN1 PTPRO SYN2 SYT4 ATP2B2

1.98e-051351307gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k3
CoexpressionAtlascerebral cortex

KIF1A KIAA0513 SMIM18 FRMPD2 PCDH11Y BRSK2 CHST1 RTN1 CRB1 NDST3 KCNF1 ABCC8 MANEAL PCDH19 SYN2 SYT4 CPNE4 BRSK1 ATP1B2 PADI2 ATP2B2 PCDH9

5.35e-05142813022cerebral cortex
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MPZ HTR3A KIF1A SMIM18 RTN1 SYN2 SYT4 ATP2B2

1.49e-071791478e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF1A BRSK2 RTN1 CRB1 PTPRO MANEAL SYN2 SYT4

1.77e-0718314789dfb398b9995d562864fe688861a831ada0814cd
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A BRSK2 RTN1 CRB1 MANEAL SYN2 SYT4

1.92e-071851478512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CPAMD8 CYP2B6 HMCN1 CELF2 ST6GALNAC3 C3 CPNE4 ATL2

2.55e-071921478356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 HERC1 PADI2

1.71e-061721477c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 HERC1 PADI2

1.71e-061721477953b05f776348cff784e79c93df65841939d880f
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RTN1 ABCC8 MANEAL SYN2 SYT4 PLCXD3 CPNE4

2.00e-0617614772e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A BRSK2 RTN1 ABCC8 SYT4 ATP2B2

2.50e-061821477a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 UROC1 DNAI1 DAW1 HYDIN

2.68e-0618414775daff849625f2f41d56615569c0ed59cd733b34c
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A KIF1A SMIM18 RTN1 SYT4 PLCXD3 ATP2B2

2.88e-06186147724b23880d4ff8fb4a23e2012d5890b9e2fcf7283
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

2.88e-06186147785787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMIM18 ITGB4 NDST3 ABCC8 BRSK1 ATP2B2 HYDIN

3.09e-061881477ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A KIF1A SMIM18 RTN1 ABCC8 PCDH19 SYT4

3.09e-061881477bd091503f580dedab40e0996273101285d24b586
ToppCellwk_15-18-Epithelial-PNS-PCP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A SMIM18 RTN1 SYN2 SYT4 ATP2B2

3.20e-06189147722c927d2691b867fbdee1fbee042a6d3f7eadd7d
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A SMIM18 CHST1 RTN1 MANEAL SYT4

3.43e-061911477df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST1 RTN1 KCNF1 SYN2 SYT4 CPNE4 ATP2B2

3.68e-061931477be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MPZ KIF1A SMIM18 RTN1 SYN2 SYT4 ATP2B2

3.68e-061931477ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST1 RTN1 KCNF1 SYN2 SYT4 CPNE4 ATP2B2

3.68e-0619314770c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST1 RTN1 KCNF1 SYN2 SYT4 CPNE4 ATP2B2

3.68e-0619314778689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

3.80e-0619414771ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

3.94e-061951477e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A KIF1A SMIM18 RTN1 ABCC8 PCDH19 SYT4

3.94e-0619514775a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

4.07e-061961477d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA3A DNAH3 TCP11X2 FRMPD2 DNAI1 DAW1 HYDIN

4.21e-06197147715b4d1203943ce90a7083178d4a4284d9b323071
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A KIF1A BRSK2 RTN1 ABCC8 MANEAL SYT4

4.21e-061971477a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

SMIM18 RTN1 NDST3 CELF2 PTPRO SYT4 CPNE4

4.65e-06200147744bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

1.24e-051541476f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 TRPC6 PEX7 CC2D2A GPNMB BRSK1

1.65e-0516214767d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

1.77e-051641476f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

1.77e-051641476dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

2.17e-051701476bca78719c17355772ad6c53ee75e459faf1d089f
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

2.17e-05170147640d863554ec98ae43f76511c1112859688846613
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

2.32e-0517214766503e85182eb6e8a40a890e393e9ac5c5350e322
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 TEC GRM6 ADORA3 ARRB2 PADI2

2.32e-0517214763c0bf7200e582ee730af49dcd86446e112226aca
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 GRM6 ADORA3 HYLS1 PADI2 TEC

2.55e-0517514761b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 GRM6 ADORA3 HYLS1 PADI2 TEC

2.55e-051751476a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A SMIM18 RTN1 SYT4 CPNE4 ATP2B2

2.64e-05176147604dad262929581872e5bbc66cd8182c963e7e52f
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 GRM6 ADORA3 GLB1 PADI2 TEC

2.64e-0517614768e4600efeea095a92178cfd26d7c58db7dfc0c80
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPZ KIF1A BRSK2 CRB1 PTPRO MANEAL

2.81e-05178147638ffbd01230c99f52274424ee6c172381daffc73
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA9 ABCA8 PIEZO2 ALX1 PLCXD3 OSMR

2.81e-05178147678a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPZ KIF1A BRSK2 CRB1 MANEAL SYN2

2.90e-051791476df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 GRM6 ADORA3 ST6GALNAC3 PADI2 TEC

2.99e-05180147641e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.08e-0518114765a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.08e-051811476a4e891603645f694687e68e585744ddc1a3c8697
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A ADGRL4 HMCN1 ST6GALNAC3 PCDH19 OSMR

3.18e-0518214763b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A ADGRL4 HMCN1 ST6GALNAC3 PCDH19 OSMR

3.18e-051821476ab5761bf9af439231cd0f487b6467e372672a517
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.28e-051831476b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.28e-051831476cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HTR3A SMIM18 RTN1 MANEAL SYN2 SYT4

3.38e-051841476571136c832cb8c08457744152231537aa8e8abd7
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC6 DNAI1 PIEZO2 KCNF1 ATP1B2 HYDIN

3.38e-0518414761c857126c0ea0671f0d60b048efca288d348d653
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A KIF1A SMIM18 RTN1 MANEAL SYN2

3.48e-0518514763d6711030ca4328357b06d5497cf98cdefcd7f4f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CPAMD8 CYP2B6 CYP11A1 ST6GALNAC3 ATL2 PCDH9

3.48e-051851476673f0c688ae6984bc8027df2da335787924f4137
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A DNAH3 FRMPD2 DNAI1 CC2D2A HYDIN

3.48e-0518514765e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 UROC1 DNAI1 HYDIN

3.48e-05185147630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

MPZ HTR3A KIF1A RTN1 MANEAL SYT4

3.48e-051851476d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.48e-05185147618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A SMIM18 RTN1 SYT4 CPNE4 ATP2B2

3.48e-051851476edb114487206e4e8df4c7878285df40f49b7fd64
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0513 BRSK2 RTN1 ABCC8 SYT4 PLCXD3

3.59e-051861476d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellPCW_07-8.5-Neuronal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPZ HTR3A BRSK2 CRB1 SYN2 SYT4

3.59e-0518614767a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGB4 ADGRL4 ST6GALNAC3 ABCC8 PLCXD3 OSMR

3.70e-051871476e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA9 ABCA8 ALX1 PLCXD3 OSMR LARGE1

3.70e-05187147676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPZ ARMCX5 NDST3 BRSK1 ATP1B2 PCDH9

3.70e-0518714768e8b147258982b359447add5027318f5b6d51963
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

VWA3A FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

3.70e-0518714761a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.81e-05188147634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.81e-0518814762b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-051891476a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-05189147668a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-051891476dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

CPAMD8 ITGB4 ADGRL4 HMCN1 ST6GALNAC3 PLCXD3

3.93e-051891476fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-051891476a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCellMulticiliated|World / shred by cell class for nasal brushing

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-05189147634b110aef839376228c5a403a6b5047a945f472b
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-051891476b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-05189147627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellE12.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MPZ HTR3A SMIM18 RTN1 NDST3 SYT4

3.93e-051891476620d30bb6211fff6adab0638d0d994f547167a29
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

3.93e-05189147693b1026bb1ba759e5704561c9a5de14a30c08894
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.04e-0519014767031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A SMIM18 RTN1 MANEAL SYT4

4.16e-0519114763a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-0519114762a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-05191147646c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-051911476ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-051911476995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-051911476a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-0519114762d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.16e-0519114766228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.29e-051921476d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

VWA3A DNAH3 FRMPD2 DNAI1 DAW1 HYDIN

4.29e-051921476354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGB4 ADGRL4 ST6GALNAC3 ABCC8 PLCXD3 OSMR

4.41e-0519314769ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRL4 SEMA3D HMCN1 CASKIN2 ST6GALNAC3 ADAMTS18

4.41e-0519314761f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellAdult-Endothelial|Adult / Lineage, Cell type, age group and donor

ADGRL4 SEMA3D CASKIN2 ST6GALNAC3 SYN2 PLCXD3

4.54e-051941476963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell18-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

MPZ HTR3A KIF1A SMIM18 RTN1 SYT4

4.54e-051941476d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWA3A DNAH3 FRMPD2 DNAI1 CC2D2A HYDIN

4.67e-0519514763486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 FRMPD2 DNAI1 DAW1 CC2D2A HYDIN

4.81e-05196147627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HTR3A KIF1A SMIM18 CHST1 RTN1 SYT4

4.81e-051961476afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCellprimary_visual_cortex-Neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIF1A RTN1 PREPL SYN2 SYT4 ATP2B2

4.81e-0519614768efc2b3a95f57c31be203ac781b2098d4909297f
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIF1A RTN1 PREPL SYN2 SYT4 ATP2B2

4.81e-051961476de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A SMIM18 RTN1 ABCC8 MANEAL SYT4

4.95e-05197147627c044833e471a312a572e0b1c83e4bc8a36e896
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA9 ABCA8 SEMA3D C3 ATP1B2 STEAP1

4.95e-05197147631c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWA3A DNAH3 FRMPD2 DAW1 CC2D2A HYDIN

4.95e-051971476e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWA3A DNAH3 FRMPD2 DAW1 CC2D2A HYDIN

4.95e-051971476d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VWA3A DNAH3 DNAI1 DAW1 HYLS1 PLK4

5.09e-051981476f31790442ef142f1c0c49bf3daf2d0efb193d2c9
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.00e-344614620DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 NAA15 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.89e-326914621DOID:1682 (implicated_via_orthology)
DiseaseIntellectual Disability

NAA15 BRSK2 KDM3B FARSB UROC1 PREPL AGO1 SNX27 SERAC1 MED23 LARGE1

1.49e-0544714611C3714756
Diseaseserine/threonine-protein kinase BRSK2 measurement

BRSK2 BRSK1

7.27e-0531462EFO_0803063
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.45e-0441462EFO_0020830
Diseasechildhood trauma measurement

NDST3 ST6GALNAC3 PCDH9

2.23e-04241463EFO_0007979
DiseaseCiliopathies

PCARE CRB1 NEK8 HYLS1 CC2D2A

2.23e-041101465C4277690
Diseasedepressive symptom measurement

TOPAZ1 UBE3B CRB1 ADGRL4 CELF2 SYN2 HERC1 PCDH9 LARGE1

2.84e-044261469EFO_0007006
DiseaseGlobal developmental delay

INTS1 BRSK2 KDM3B AGO1 SNX27

5.35e-041331465C0557874
DiseaseColorectal Carcinoma

DNAH3 CPAMD8 FRMPD2 ABCA9 ABCA8 NDST3 ADORA3 ABCC8 ADAMTS18 MMP1 GPNMB

7.69e-0470214611C0009402
DiseaseSeizures

CYP11A1 KDM3B GLB1 HACE1 SYN2 SNX27

7.80e-042181466C0036572
Diseasevisceral heterotaxy (implicated_via_orthology)

DNAI1 DAW1 CC2D2A

8.15e-04371463DOID:0050545 (implicated_via_orthology)
Diseaseoverall survival

OSMR PCDH9

8.56e-0491462EFO_0000638
DiseaseRetinal Detachment

CPAMD8 CRB1

1.30e-03111462C0035305
Diseasesciatic neuropathy (biomarker_via_orthology)

MPZ CYP11A1 ABCC8 C3

1.50e-03991464DOID:11446 (biomarker_via_orthology)
Diseasetemporal pole volume measurement

PTPRO SYT4

1.55e-03121462EFO_0010334
Diseasetyrosine-protein kinase ZAP-70 measurement

C3 PLCXD3

1.55e-03121462EFO_0020833
DiseaseHereditary Motor and Sensory-Neuropathy Type II

MPZ KIF1A

1.83e-03131462C0270914
DiseaseKartagener syndrome (implicated_via_orthology)

DNAI1 DAW1

2.13e-03141462DOID:0050144 (implicated_via_orthology)
Disease3-hydroxyphenylacetic acid measurement

PIEZO2 STEAP1B

2.13e-03141462EFO_0010448
Diseasewellbeing measurement

UBE3B ADGRL4 SGMS1 CELF2 SND1 SYN2 LRRC28 HERC1 PCDH9 LARGE1

2.41e-0369214610EFO_0007869
DiseaseGeneralized hypotonia

AGO1 SNX27

2.45e-03151462C1858120
DiseaseColorectal Neoplasms

CPAMD8 ABCA9 ABCA8 ABCC8 MMP1 GPNMB

2.63e-032771466C0009404
DiseaseSpondyloepiphyseal Dysplasia

FLNA GLB1

2.79e-03161462C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLNA GLB1

2.79e-03161462C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

FLNA GLB1

2.79e-03161462C4551479
DiseaseAbnormal behavior

BRSK2 KDM3B

2.79e-03161462C0233514
DiseaseSchwartz-Jampel Syndrome

FLNA GLB1

2.79e-03161462C0036391
DiseaseMelnick-Needles Syndrome

FLNA GLB1

2.79e-03161462C0025237
DiseaseVan Buchem disease

FLNA GLB1

3.15e-03171462C0432272
DiseaseMeckel syndrome type 1

HYLS1 CC2D2A

3.53e-03181462C3714506
DiseaseAge-related macular degeneration

HMCN1 C3

3.53e-03181462cv:C0242383
Diseasecystathionine measurement

TEC TEC

3.93e-03191462EFO_0010474
DiseaseOsteochondrodysplasias

FLNA GLB1

3.93e-03191462C0029422
DiseaseDyschondroplasias

FLNA GLB1

3.93e-03191462C0013366
DiseaseDisorder of eye

PEX7 PCARE GRM6 CRB1 CC2D2A

4.16e-032121465C0015397
DiseaseMultiple Epiphyseal Dysplasia

FLNA GLB1

4.36e-03201462C0026760
Diseaseesophagus adenocarcinoma (is_implicated_in)

BIRC3 MMP1

4.80e-03211462DOID:4914 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
FQKTHYPDVYVREQL

ALX1

151

Q15699
YLIVVGVIYNKGFLH

ADGRL4

516

Q9HBW9
LKELFEPYGAVYQIN

CELF2

56

O95319
YFPGAHRQVYKNLQE

CYP2B6

226

P20813
CIIYFNGEVPQLVLY

ADORA3

251

P0DMS8
GEHLVFKYNLRVPYG

ADAM7

151

Q9H2U9
IPQLLEHLFYESYQK

ABCA9

876

Q8IUA7
AQVVGVLKIQVHYYE

CAPZA1

186

P52907
HGRAYVPIAQVKDVY

GPNMB

216

Q14956
YVYIRHQGEVQNYKP

HTR3A

136

P46098
YQPGITYIVVQKRHH

AGO1

696

Q9UL18
IKQGHIPELQEYVKY

ASB15

51

Q8WXK1
FKVHQYFNVELIQPG

C3

1461

P01024
YFNVELIQPGAVKVY

C3

1466

P01024
LYEHLFVQQDIKYIP

BIRC3

521

Q13489
YKPIGFVNQLAVHYT

DNAI1

91

Q9UI46
KKYQEYIPVQTGAHA

DHX29

806

Q7Z478
HGPYYQTLAEIKKQI

ARMCX5

271

Q6P1M9
KELYYHGEPLNVNVH

ARRB2

206

P32121
VVQAYVGDVHYKEIP

ATP2B2

511

Q01814
LNQHKANEYYPVVLI

ADAMTS18

756

Q8TE60
DEVQKFLGVLPHYNY

NDST3

781

O95803
ESQPGFIQGYHVYLK

OSMR

651

Q99650
YVHYGEVVQLPLEFV

IPPK

71

Q9H8X2
GEKIYLYTHLKQQPI

KIAA0513

286

O60268
PHFSKPYYQVIVQEN

PCDH19

451

Q8TAB3
QYIHVTGTVFLQLPY

DEPDC5

1501

O75140
YHIVYKEGQFYPVNL

LARGE1

531

O95461
GNYIFQVIVNPHYEV

LOXL4

691

Q96JB6
IYLQDVQMVHPKFYG

GLIPR1L2

101

Q4G1C9
QFIHKYITYNAPAAI

INTS1

1961

Q8N201
PGFEKRLQLYQLFHY

FN3KRP

271

Q9HA64
YGKKFHVNYTQPLVA

ATP1B2

231

P14415
HLEFKVNYTDYIQPI

TMPRSS15

881

P98073
LQEQYAYEKPHVVCG

HERC1

3861

Q15751
QHAQYVGPYRLEKTL

BRSK2

11

Q8IWQ3
LYPLTFIQVKQHYGF

GLB1

401

P16278
IKQIAQPGAAYFYVE

CWF19L1

456

Q69YN2
LNIIDLQFLHGYYEP

CPSF1

201

Q10570
QYIHIFLANLYVVVP

OR52E6

271

Q96RD3
EVPFHLKAVYDNQYL

PCDH9

406

Q9HC56
AGPLQVYKEHAQEVY

PEX7

101

O00628
FYKHILGIPVNYQDV

HACE1

666

Q8IYU2
TEFQLLYVYHLVGPF

MED23

1241

Q9ULK4
KFHLQNTLYPQYDPV

NIPBL

1341

Q6KC79
VVYAIAFNNPYGDKI

DAW1

136

Q8N136
KLLNHPNVIEYYENF

NEK8

56

Q86SG6
YSVQGHRVKIYQPEG

KDM3B

196

Q7LBC6
YAVPEKIGQVHYALE

LNPEP

381

Q9UIQ6
TFLKNGEPYYILQHP

LMTK2

181

Q8IWU2
YVENPFFGQRYIHIL

PADI2

216

Q9Y2J8
IHDYLYFQVLSPGDI

PRADC1

26

Q9BSG0
YNPLYKERHQVQLLG

DDX23

286

Q9BUQ8
KHNIIPIFAVTNYSY

ITGB4

316

P16144
QIPLHLAAQYGHYEV

CASKIN2

116

Q8WXE0
KHGIYVQAINYPTVP

ALAS2

496

P22557
VQYYLAQHYDKIGQP

NAA15

376

Q9BXJ9
YIDKGQYLHIPRAQV

HMCN1

1596

Q96RW7
GVLFEIHYPEKYNVF

PTPRO

136

Q16827
IHYPEKYNVFTRVNI

PTPRO

141

Q16827
LEPPNFFQKYRHYIV

PAPOLG

361

Q9BWT3
YVHPNQVDFGNIYVL

HYDIN

806

Q4G0P3
QHIYVPNNYLVPTEK

HYLS1

256

Q96M11
YVPKTYVILFHPEQN

GRM6

836

O15303
VEFALAVYIHPYPKN

CC2D2A

1591

Q9P2K1
AEKQQQPPTVYLLHY

CABIN1

1216

Q9Y6J0
QNYARKYTIPIDHIG

DNAH3

3981

Q8TD57
PVVHEIAYQYGKNVG

PDSS1

286

Q5T2R2
DYSILVKYNEQHVPG

FLNA

1931

P21333
NYPKEQVESKPYFHV

FRMPD2

481

Q68DX3
VHISTPNKYEFQYVQ

CPAMD8

951

Q8IZJ3
HPYQPNEYLKALVAV

CPNE4

331

Q96A23
FKAYIKIYQGEELPH

ATL2

356

Q8NHH9
LHHVQNFQKYGPIYR

CYP11A1

76

P05108
QHAQYVGPYRLEKTL

BRSK1

26

Q8TDC3
QYSIQVAFHIQPYKG

MANEAL

216

Q5VSG8
YLSYFENVHGFINKP

CRB1

1106

P82279
VYQDPQGRHVKTYEV

DDB1

181

Q16531
YIKSQPIVFEVFGHY

KIF1A

1066

Q12756
VFTHNEYKFYVPENL

PCDH11Y

601

Q9BZA8
FPEPLVKAHQQAYTY

PCARE

176

A6NGG8
PVVYVKHQAQIDQYL

RTN1

736

Q16799
YGIPYTQIQELALHF

SYT4

226

Q9H2B2
FYQSLGIPYHIVNIV

SARS1

351

P49591
GEKFPLIEQTYYPNH

SYN2

241

Q92777
VQEKYQDGVYVLHPQ

SERAC1

371

Q96JX3
GVQPEHIQYLKNYFH

SMCHD1

326

A6NHR9
AYAHPQQKVAVYRAL

TRADD

31

Q15628
HHNQQVFGPYYAEIL

TCP11X2

376

Q5H9J9
NKYPFQVVHDANTLY

TEC

76

P42680
QYVYVDNNIHLKGLP

LRRC28

206

Q86X40
VQGQNVLHGYPKDIY

MMP1

351

P03956
FGEYVAEILPKYVQQ

NDUFS3

61

O75489
HLDPAVKEVQYNPTY

CDC40

71

O60508
TEYYPHLVFLQNKAR

SMG9

361

Q9H0W8
YLGFQVQKIYPFHDN

SMIM18

16

P0DKX4
AFHQGIYPELYSILE

SIX4

156

Q9UIU6
HYGYINVKTQEPLQL

ST6GALNAC3

61

Q8NDV1
YQKPEGNHIIKVGIY

SHPRH

201

Q149N8
PAKIHVFYIDYGNRE

SND1

756

Q7KZF4
YVFGDHPLIQFQYIR

PIK3CB

256

P42338
QLKHPSILELYNYFE

PLK4

66

O00444
YYNKNPGFEIIHGLL

FARSB

501

Q9NSD9
FIRVLQPYNKTHIYV

SEMA3D

131

O95025
SHQQYFYKIPILVIN

STEAP1

101

Q9UHE8
TSHQQYFYKIPILVI

STEAP1B

81

Q6NZ63
AIYFEKILPNEYGHR

ABCA8

416

O94911
VVYYHNIETSNFPKL

ABCC8

121

Q09428
SYHSYVIGFVVPNQK

ACSL3

616

O95573
VFYLFEPLYHVQNTL

CHST1

86

O43916
EKDYQVLVFYHSPVA

PLCXD3

186

Q63HM9
NTGPLVYVLYAVLVH

USP17L3

311

A6NCW0
NTGPLVYVLYAVLVH

USP17L4

311

A6NCW7
APEFAQELQLYGHIY

UROC1

61

Q96N76
QYEIVDYLGPRKHFI

STPG1

271

Q5TH74
YGGIPAFIHAKQQYI

TIMMDC1

91

Q9NPL8
NTGPLVYVLYAVLVH

USP17L18

311

D6R9N7
EIYVPIKQFFYNLIH

PIEZO2

2166

Q9H5I5
NTGPLVYVLYAVLVH

USP17L5

311

A8MUK1
NTGPLVYVLYAVLVH

USP17L21

311

D6R901
NTGPLVYVLYAVLVH

USP17L13

311

C9JLJ4
DVHQVYKYPFEQVVA

PRELID2

6

Q8N945
YFEKNVQGIVPRSYH

SGMS1

376

Q86VZ5
EFPHKLYIQNYTSAV

SNX27

336

Q96L92
NTGPLVYVLYAVLVH

USP17L19

311

D6RCP7
INVEVKHGGFVYYQE

PREPL

111

Q4J6C6
NTGPLVYVLYAVLVH

USP17L1

311

Q7RTZ2
HLPELQLFQYEGKIY

ZNF347

191

Q96SE7
QRYPGYFKVDHIKGI

ZNF658

76

Q5TYW1
DPEHFNYIVKLLYQV

TOPAZ1

1236

Q8N9V7
NTGPLVYVLYAVLVH

USP17L12

311

C9JPN9
YIHENYLQLFEFVGK

UBE3B

766

Q7Z3V4
AYIKQQGIHFREKPY

ZNF655

366

Q8N720
KHVDAQGRIYLPYLQ

UEVLD

101

Q8IX04
NTGPLVYVLYAVLVH

USP17L24

311

Q0WX57
IQFNKHLLSTYYVPG

ZNF74

586

Q16587
NTGPLVYVLYAVLVH

USP17L7

311

P0C7H9
NTGPLVYVLYAVLVH

USP17L8

311

P0C7I0
VVINYNHKFIENIGY

TRPC6

691

Q9Y210
NHKFIENIGYVLYGV

TRPC6

696

Q9Y210
NTGPLVYVLYAVLVH

USP17L6P

311

Q6QN14
VQYPGQHLQLLLKYF

TRAV8-1

56

A0A0A6YYK1
NTGPLVYVLYAVLVH

USP17L22

311

D6RA61
LHQYSKAPVYLFEQV

UBR4

866

Q5T4S7
NSGPLVYVLYAVLVH

USP17L15

311

C9J2P7
NTGPLVYVLYAVLVH

USP17L17

311

D6RBQ6
INRKVQLTYYPHGVK

PPIP5K1

486

Q6PFW1
NTGPLVYVLYAVLVH

USP17L2

311

Q6R6M4
KNIHVDPPFLYKYQQ

VWA3A

466

A6NCI4
NTGPLVYVLYAVLVH

USP17L20

311

D6RJB6
VYKAVGHYNVAIPSD

TMEM39B

391

Q9GZU3
NTGPLVYVLYAVLVH

USP17L10

311

C9JJH3
NTGPLVYVLYAVLVH

USP17L11

311

C9JVI0
PIHPIINNFVRYYNK

KCNF1

401

Q9H3M0
YGQHPNIITLKDVYD

RPS6KA1

466

Q15418
AISIFHYAKGQPYID

MPZ

76

P25189