Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	2.43e-05	2	99	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	2.43e-05	2	99	2	GO:0001566
GeneOntologyMolecularFunction	MHC class Ib protein binding	KIR3DL3 KIR2DL4 KIR2DS4	6.32e-05	16	99	3	GO:0023029
GeneOntologyMolecularFunction	diacylglycerol binding	UNC13B UNC13C UNC13A	6.32e-05	16	99	3	GO:0019992
GeneOntologyMolecularFunction	ceramide cholinephosphotransferase activity	SGMS2 SGMS1	7.28e-05	3	99	2	GO:0047493
GeneOntologyMolecularFunction	ceramide phosphoethanolamine synthase activity	SGMS2 SGMS1	7.28e-05	3	99	2	GO:0002950
GeneOntologyMolecularFunction	sphingomyelin synthase activity	SGMS2 SGMS1	7.28e-05	3	99	2	GO:0033188
GeneOntologyMolecularFunction	MHC class Ib receptor activity	KIR3DL3 KIR2DL4 KIR2DS4	1.08e-04	19	99	3	GO:0032394
GeneOntologyMolecularFunction	syntaxin-1 binding	UNC13B UNC13C UNC13A	2.22e-04	24	99	3	GO:0017075
GeneOntologyMolecularFunction	kinase activity	SGMS2 AVP KSR2 RIPK4 CCNH KSR1 MAST4 SGMS1 SHPK KHK ULK1 ULK2	3.95e-04	764	99	12	GO:0016301
GeneOntologyMolecularFunction	steroid hormone binding	ATP1A2 ATP1A3	5.03e-04	7	99	2	GO:1990239
GeneOntologyMolecularFunction	urea transmembrane transporter activity	SLC14A1 SLC14A2	8.56e-04	9	99	2	GO:0015204
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A2 ATP1A3	1.07e-03	10	99	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A2 ATP1A3	1.07e-03	10	99	2	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A2 ATP1A3	1.30e-03	11	99	2	GO:0008556
GeneOntologyMolecularFunction	secondary active sulfate transmembrane transporter activity	SLC26A3 SLC13A4	1.30e-03	11	99	2	GO:0008271
GeneOntologyMolecularFunction	chloride:bicarbonate antiporter activity	SLC26A3 SLC4A8	1.83e-03	13	99	2	GO:0140900
GeneOntologyMolecularFunction	MAP-kinase scaffold activity	KSR2 KSR1	1.83e-03	13	99	2	GO:0005078
GeneOntologyMolecularFunction	bicarbonate:monoatomic anion antiporter activity	SLC26A3 SLC4A8	1.83e-03	13	99	2	GO:0140829
GeneOntologyMolecularFunction	aminoacyl-tRNA editing activity	LARS2 VARS1	2.13e-03	14	99	2	GO:0002161
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SGMS2 AVP KSR2 RIPK4 CCNH KSR1 MAST4 SGMS1 SHPK KHK ULK1 ULK2	2.32e-03	938	99	12	GO:0016772
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13C UNC13A	4.15e-07	4	98	3	GO:0061789
GeneOntologyBiologicalProcess	presynaptic dense core vesicle exocytosis	UNC13B UNC13C UNC13A	1.22e-05	10	98	3	GO:0099525
GeneOntologyBiologicalProcess	secretory granule localization	UNC13B MYO5C UNC13C UNC13A	1.99e-05	34	98	4	GO:0032252
GeneOntologyBiologicalProcess	neuronal dense core vesicle exocytosis	UNC13B UNC13C UNC13A	2.22e-05	12	98	3	GO:0099011
GeneOntologyBiologicalProcess	somatic sensory system development	ULK1 ULK2	2.23e-05	2	98	2	GO:0160038
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	2.23e-05	2	98	2	GO:0061790
GeneOntologyBiologicalProcess	tetrapyrrole catabolic process	SLCO2B1 CUBN UGT1A1	3.64e-05	14	98	3	GO:0033015
GeneOntologyBiologicalProcess	dense core granule exocytosis	UNC13B UNC13C UNC13A	4.54e-05	15	98	3	GO:1990504
GeneOntologyBiologicalProcess	L-ascorbic acid metabolic process	SELENON ATP1A2 ATP1A3	5.57e-05	16	98	3	GO:0019852
GeneOntologyBiologicalProcess	synaptic vesicle docking	UNC13B UNC13C UNC13A	6.74e-05	17	98	3	GO:0016081
GeneOntologyBiologicalProcess	lactone metabolic process	SELENON ATP1A2 ATP1A3	9.54e-05	19	98	3	GO:1901334
GeneOntologyBiologicalProcess	regulation of short-term neuronal synaptic plasticity	UNC13B ATP1A3 UNC13A	1.50e-04	22	98	3	GO:0048172
GeneOntologyBiologicalProcess	transmission of nerve impulse	GHRL AVP CLCN1 ATP1A2 ATP1A3	1.96e-04	112	98	5	GO:0019226
GeneOntologyBiologicalProcess	response to glycoside	ATP1A2 ATP1A3	2.21e-04	5	98	2	GO:1903416
GeneOntologyBiologicalProcess	regulation of collateral sprouting	SEMA4D ULK1 ULK2	2.22e-04	25	98	3	GO:0048670
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	UNC13B UNC13C UNC13A	2.22e-04	25	98	3	GO:0048791
GeneOntologyBiologicalProcess	dense core granule localization	UNC13B UNC13C UNC13A	3.13e-04	28	98	3	GO:0032253
GeneOntologyBiologicalProcess	negative regulation of synaptic plasticity	UNC13B UNC13C	3.31e-04	6	98	2	GO:0031914
GeneOntologyBiologicalProcess	synaptic vesicle priming	UNC13B UNC13C UNC13A	4.24e-04	31	98	3	GO:0016082
GeneOntologyBiologicalProcess	water-soluble vitamin metabolic process	CUBN SELENON ATP1A2 ATP1A3	4.27e-04	74	98	4	GO:0006767
GeneOntologyBiologicalProcess	response to sucrose	PNPLA3 KHK	4.62e-04	7	98	2	GO:0009744
GeneOntologyCellularComponent	calyx of Held	UNC13B UNC13C ATP1A3 UNC13A	2.48e-05	36	99	4	GO:0044305
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	UNC13B UNC13C UNC13A	1.70e-04	23	99	3	GO:0098831
Domain	Unc-13	UNC13B UNC13C UNC13A	1.44e-07	3	99	3	IPR027080
Domain	Munc13_dom-2	UNC13B UNC13C UNC13A	1.43e-06	5	99	3	IPR014772
Domain	Membr_traf_MHD	UNC13B UNC13C UNC13A	1.43e-06	5	99	3	PF10540
Domain	MHD2	UNC13B UNC13C UNC13A	1.43e-06	5	99	3	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C UNC13A	1.43e-06	5	99	3	IPR019558
Domain	DUF1041	UNC13B UNC13C UNC13A	1.43e-06	5	99	3	SM01145
Domain	DUF1041	UNC13B UNC13C UNC13A	4.98e-06	7	99	3	PF06292
Domain	Munc13_1	UNC13B UNC13C UNC13A	4.98e-06	7	99	3	IPR014770
Domain	CAPS_dom	UNC13B UNC13C UNC13A	4.98e-06	7	99	3	IPR010439
Domain	MHD1	UNC13B UNC13C UNC13A	4.98e-06	7	99	3	PS51258
Domain	C1_1	UNC13B KSR2 KSR1 UNC13C UNC13A	1.27e-05	57	99	5	PF00130
Domain	ZF_DAG_PE_1	UNC13B KSR2 KSR1 UNC13C UNC13A	2.25e-05	64	99	5	PS00479
Domain	ZF_DAG_PE_2	UNC13B KSR2 KSR1 UNC13C UNC13A	2.25e-05	64	99	5	PS50081
Domain	C1	UNC13B KSR2 KSR1 UNC13C UNC13A	2.43e-05	65	99	5	SM00109
Domain	PE/DAG-bd	UNC13B KSR2 KSR1 UNC13C UNC13A	2.61e-05	66	99	5	IPR002219
Domain	Urea_transporter	SLC14A1 SLC14A2	2.78e-05	2	99	2	IPR004937
Domain	KSR1-SAM	KSR2 KSR1	2.78e-05	2	99	2	PF13543
Domain	Ser/Thr_kinase_C	ULK1 ULK2	2.78e-05	2	99	2	IPR022708
Domain	DUF3543	ULK1 ULK2	2.78e-05	2	99	2	PF12063
Domain	Ser/Thr_kin_STPK_Ulk-1/2	ULK1 ULK2	2.78e-05	2	99	2	IPR016237
Domain	KSR_SAM-like_dom	KSR2 KSR1	2.78e-05	2	99	2	IPR025561
Domain	UT	SLC14A1 SLC14A2	2.78e-05	2	99	2	PF03253
Domain	Sphingomyelin_synth-like_dom	SGMS2 SGMS1	8.32e-05	3	99	2	IPR025749
Domain	PAP2_C	SGMS2 SGMS1	8.32e-05	3	99	2	PF14360
Domain	Pecanex_C	PCNX3 PCNX1	1.66e-04	4	99	2	PF05041
Domain	Pecanex	PCNX3 PCNX1	1.66e-04	4	99	2	IPR007735
Domain	Val/Leu/Ile-tRNA-synth_edit	LARS2 VARS1	4.11e-04	6	99	2	IPR009008
Domain	Anticodon_1	LARS2 VARS1	4.11e-04	6	99	2	PF08264
Domain	P-type_ATPase_IIC	ATP1A2 ATP1A3	4.11e-04	6	99	2	IPR005775
Domain	M/V/L/I-tRNA-synth_anticd-bd	LARS2 VARS1	4.11e-04	6	99	2	IPR013155
Domain	-	LARS2 VARS1	4.11e-04	6	99	2	3.90.740.10
Domain	aa-tRNA-synth_Ia	LARS2 VARS1	5.74e-04	7	99	2	IPR002300
Domain	-	SLC14A1 SLC14A2	5.74e-04	7	99	2	1.10.3430.10
Domain	Ammonium/urea_transptr	SLC14A1 SLC14A2	5.74e-04	7	99	2	IPR029020
Domain	tRNA-synt_1	LARS2 VARS1	5.74e-04	7	99	2	PF00133
Domain	DHC_N1	DYNC2H1 DNAH11	7.63e-04	8	99	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH11	7.63e-04	8	99	2	IPR013594
Domain	-	LARS2 VARS1	1.48e-03	11	99	2	1.10.730.10
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH11	2.43e-03	14	99	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH11	2.43e-03	14	99	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH11	2.43e-03	14	99	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH11	2.43e-03	14	99	2	PF08393
Domain	MT	DYNC2H1 DNAH11	2.43e-03	14	99	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH11	2.43e-03	14	99	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH11	2.43e-03	14	99	2	IPR011704
Domain	AAA_5	DYNC2H1 DNAH11	2.43e-03	14	99	2	PF07728
Domain	DHC_fam	DYNC2H1 DNAH11	2.79e-03	15	99	2	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH11	2.79e-03	15	99	2	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH11	2.79e-03	15	99	2	PF03028
Domain	tRNAsynth_Ia_anticodon-bd	LARS2 VARS1	2.79e-03	15	99	2	IPR009080
Domain	-	ATP1A2 ATP1A3	3.18e-03	16	99	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A2 ATP1A3	3.18e-03	16	99	2	IPR023298
Domain	ig	SEMA4D FCER1A KIR3DL3 KIR2DL4 KIR2DS4	3.42e-03	190	99	5	PF00047
Domain	Immunoglobulin	SEMA4D FCER1A KIR3DL3 KIR2DL4 KIR2DS4	3.42e-03	190	99	5	IPR013151
Domain	ATPase_P-typ_cation-transptr_C	ATP1A2 ATP1A3	3.59e-03	17	99	2	IPR006068
Domain	Cation_ATPase_C	ATP1A2 ATP1A3	3.59e-03	17	99	2	PF00689
Domain	aa-tRNA-synth_I_CS	LARS2 VARS1	4.03e-03	18	99	2	IPR001412
Domain	Cation_ATPase_N	ATP1A2 ATP1A3	4.03e-03	18	99	2	PF00690
Domain	Cation_ATPase_N	ATP1A2 ATP1A3	4.03e-03	18	99	2	SM00831
Domain	EFTu-like_2	EFL1 GTPBP1	4.03e-03	18	99	2	IPR004161
Domain	GTP_EFTU_D2	EFL1 GTPBP1	4.03e-03	18	99	2	PF03144
Domain	G_TR_2	EFL1 GTPBP1	4.03e-03	18	99	2	PS51722
Domain	TF_GTP-bd_dom	EFL1 GTPBP1	4.48e-03	19	99	2	IPR000795
Domain	ATPase_P-typ_cation-transptr_N	ATP1A2 ATP1A3	4.48e-03	19	99	2	IPR004014
Domain	AA_TRNA_LIGASE_I	LARS2 VARS1	4.48e-03	19	99	2	PS00178
Domain	P_Acid_Pase_2/haloperoxidase	SGMS2 SGMS1	4.97e-03	20	99	2	IPR000326
Domain	PAP2	SGMS2 SGMS1	4.97e-03	20	99	2	PF01569
Domain	C2	UNC13B PLCL2 UNC13C UNC13A	5.21e-03	131	99	4	PF00168
Domain	FA58C	CNTNAP3B CNTNAP3	5.47e-03	21	99	2	SM00231
Domain	-	ACACA CDYL	5.47e-03	21	99	2	3.90.226.10
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC26A3 SLC4A8 AVP SLCO2B1 SLC13A4 SLC14A1 SLC16A2 SLC14A2 SLC7A10	9.62e-06	238	82	9	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC26A3 SLC4A8 AVP SLCO2B1 SLC13A4 SLC14A1 SLC16A2 SLC14A2 SLC7A10	1.38e-05	249	82	9	M5988
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC26A3 SLC4A8 AVP SLCO2B1 CUBN ZDHHC8 SLC13A4 CLCN1 SLC14A1 SLC16A2 ATP1A2 ATP1A3 SLC14A2 UNC79 SLC7A10	1.91e-05	736	82	15	M27287
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	AVP SLCO2B1 SLC16A2	3.03e-05	11	82	3	M930
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC26A3 SLC4A8 AVP SLCO2B1 ZDHHC8 SLC13A4 CLCN1 SLC14A1 SLC16A2 ATP1A2 ATP1A3 SLC14A2 UNC79 SLC7A10	3.43e-05	681	82	14	MM14985
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	AVP SLCO2B1 SLC16A2	4.02e-05	12	82	3	MM15476
Pathway	WP_SYNAPTIC_VESICLE_PATHWAY	UNC13B UNC13C ATP1A2 UNC13A	2.16e-04	51	82	4	M39457
Pathway	WP_SYNTHESIS_OF_CERAMIDES_AND_1DEOXYCERAMIDES	SGMS2 A3GALT2 SGMS1	2.70e-04	22	82	3	M45544
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C UNC13A	2.38e-08	3	101	3	23658173
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C UNC13A	2.38e-08	3	101	3	33105896
Pubmed	Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.	UNC13B UNC13C UNC13A	2.38e-08	3	101	3	22966208
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13C UNC13A	2.38e-08	3	101	3	15988013
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13B UNC13C UNC13A	2.37e-07	5	101	3	34706221
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13B UNC13C UNC13A	2.37e-07	5	101	3	26575293
Pubmed	Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.	KIR3DL3 KIR2DL4 KIR2DS4	8.25e-07	7	101	3	12618911
Pubmed	Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.	KIR3DL3 KIR2DL4 KIR2DS4	8.25e-07	7	101	3	15748957
Pubmed	Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.	UNC13B UNC13C UNC13A	8.25e-07	7	101	3	36398873
Pubmed	A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.	KIR3DL3 KIR2DL4 KIR2DS4	1.32e-06	8	101	3	15730517
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13B UNC13C UNC13A	1.32e-06	8	101	3	25609709
Pubmed	Distribution of KIR genes in the Czech population.	KIR3DL3 KIR2DL4 KIR2DS4	1.97e-06	9	101	3	18186800
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	UNC13B UNC13C UNC13A	3.86e-06	11	101	3	34767769
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].	KIR3DL3 KIR2DL4 KIR2DS4	5.13e-06	12	101	3	17490516
Pubmed	Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus.	SGMS2 SGMS1	8.35e-06	2	101	2	27892528
Pubmed	Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK.	KSR2 KSR1	8.35e-06	2	101	2	22801368
Pubmed	Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).	ULK1 ULK2	8.35e-06	2	101	2	30782972
Pubmed	Chlamydia trachomatis-infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2.	SGMS2 SGMS1	8.35e-06	2	101	2	31596951
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	8.35e-06	2	101	2	31150793
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	8.35e-06	2	101	2	12070347
Pubmed	Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression.	SERPINA1 PNPLA3	8.35e-06	2	101	2	37625151
Pubmed	Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum.	SGMS2 SGMS1	8.35e-06	2	101	2	27927984
Pubmed	The domain responsible for sphingomyelin synthase (SMS) activity.	SGMS2 SGMS1	8.35e-06	2	101	2	18694848
Pubmed	Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism.	SGMS2 SGMS1	8.35e-06	2	101	2	33545384
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	8.35e-06	2	101	2	12871971
Pubmed	Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.	DYNC2H1 DNAH11	8.35e-06	2	101	2	9325061
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	8.35e-06	2	101	2	17561838
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	8.35e-06	2	101	2	23070049
Pubmed	Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.	SGMS2 SGMS1	8.35e-06	2	101	2	18370930
Pubmed	Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.	SGMS2 SGMS1	8.35e-06	2	101	2	16508036
Pubmed	Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.	ULK1 ULK2	8.35e-06	2	101	2	9600096
Pubmed	Circulating levels of obestatin and copeptin in obese and nonobese women with polycystic ovary syndrome.	GHRL AVP	8.35e-06	2	101	2	25837320
Pubmed	Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes.	ULK1 ULK2	8.35e-06	2	101	2	24135897
Pubmed	Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation.	SGMS2 SGMS1	8.35e-06	2	101	2	31847800
Pubmed	Generation and phenotypic analysis of mice lacking all urea transporters.	SLC14A1 SLC14A2	8.35e-06	2	101	2	27914708
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	8.35e-06	2	101	2	28489077
Pubmed	ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.	ATP1A2 ATP1A3	8.35e-06	2	101	2	33880529
Pubmed	Role of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism.	SLC14A1 SLC14A2	8.35e-06	2	101	2	21849488
Pubmed	Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation.	SGMS2 SGMS1	8.35e-06	2	101	2	22209789
Pubmed	The murine urea transporter genes Slc14a1 and Slc14a2 occur in tandem on chromosome 18.	SLC14A1 SLC14A2	8.35e-06	2	101	2	10640821
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	8.35e-06	2	101	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	8.35e-06	2	101	2	22066784
Pubmed	The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy.	ULK1 ULK2	8.35e-06	2	101	2	21460635
Pubmed	Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.	SGMS2 SGMS1	8.35e-06	2	101	2	22106271
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	8.35e-06	2	101	2	32187536
Pubmed	Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3.	SLC14A1 SLC14A2	8.35e-06	2	101	2	26407594
Pubmed	Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes.	ULK1 ULK2	8.35e-06	2	101	2	33149253
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	8.35e-06	2	101	2	28772123
Pubmed	The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.	ATP1A2 ATP1A3	8.35e-06	2	101	2	18957371
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	8.35e-06	2	101	2	26807827
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	8.35e-06	2	101	2	17267576
Pubmed	ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.	ULK1 ULK2	8.35e-06	2	101	2	27153534
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	8.35e-06	2	101	2	22814762
Pubmed	Expression of urea transporters in potassium-depleted mouse kidney.	SLC14A1 SLC14A2	8.35e-06	2	101	2	12952854
Pubmed	SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.	SGMS2 SGMS1	8.35e-06	2	101	2	17982138
Pubmed	2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.	SGMS2 SGMS1	8.35e-06	2	101	2	30305392
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	8.35e-06	2	101	2	28426965
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	8.35e-06	2	101	2	35613050
Pubmed	Cloning and functional expression of a urea transporter from human bone marrow cells.	SLC14A1 SLC14A2	8.35e-06	2	101	2	7989337
Pubmed	Water transport mediated by murine urea transporters: implications for urine concentration mechanisms.	SLC14A1 SLC14A2	8.35e-06	2	101	2	32661130
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	8.35e-06	2	101	2	23770256
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	8.35e-06	2	101	2	30816091
Pubmed	Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.	SGMS2 SGMS1	8.35e-06	2	101	2	17449912
Pubmed	Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.	SGMS2 SGMS1	8.35e-06	2	101	2	17616479
Pubmed	Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes.	SLC14A1 SLC14A2	8.35e-06	2	101	2	18256317
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	8.35e-06	2	101	2	22674279
Pubmed	Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly.	ZDHHC5 ZDHHC8	8.35e-06	2	101	2	25049274
Pubmed	KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.	KSR2 KSR1	8.35e-06	2	101	2	19883615
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	8.35e-06	2	101	2	19558619
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	8.35e-06	2	101	2	18701688
Pubmed	Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.	ULK1 ULK2	8.35e-06	2	101	2	23291478
Pubmed	Functional differentiation of the human red blood cell and kidney urea transporters.	SLC14A1 SLC14A2	8.35e-06	2	101	2	8997401
Pubmed	Molecular characterization of a new urea transporter in the human kidney.	SLC14A1 SLC14A2	8.35e-06	2	101	2	8647271
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	8.35e-06	2	101	2	31851910
Pubmed	Sphingomyelin synthases regulate protein trafficking and secretion.	SGMS2 SGMS1	8.35e-06	2	101	2	21980337
Pubmed	An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis.	SGMS2 SGMS1	8.35e-06	2	101	2	19001565
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	8.35e-06	2	101	2	11832228
Pubmed	Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.	ATP1A2 ATP1A3	8.35e-06	2	101	2	24356962
Pubmed	Vasopressin regulation of the proestrous luteinizing hormone surge in wild-type and Clock mutant mice.	AVP CLOCK	8.35e-06	2	101	2	16870944
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	8.35e-06	2	101	2	23229896
Pubmed	Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle.	ULK1 ULK2	8.35e-06	2	101	2	34658916
Pubmed	Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice.	SGMS2 SGMS1	8.35e-06	2	101	2	22641779
Pubmed	A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons.	ULK1 ULK2	8.35e-06	2	101	2	10624947
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	8.35e-06	2	101	2	11792326
Pubmed	Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis.	KSR2 KSR1	8.35e-06	2	101	2	28180061
Pubmed	Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity.	SGMS2 SGMS1	8.35e-06	2	101	2	34774525
Pubmed	Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.	KIR3DL3 KIR2DL4 KIR2DS4	8.45e-06	14	101	3	19875891
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.	KIR3DL3 KIR2DL4 KIR2DS4	8.45e-06	14	101	3	15896204
Pubmed	[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].	KIR3DL3 KIR2DL4 KIR2DS4	8.45e-06	14	101	3	19489269
Pubmed	Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.	KIR3DL3 KIR2DL4 KIR2DS4	8.45e-06	14	101	3	18945962
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	20082646
Pubmed	Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	19926642
Pubmed	[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	20356536
Pubmed	Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	20643584
Pubmed	KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	17498266
Pubmed	Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.	KIR3DL3 KIR2DL4 KIR2DS4	1.05e-05	15	101	3	19326408
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CNTNAP3 ZDHHC5 THADA SPHKAP PHACTR1	1.25e-05	102	101	5	11214970
Pubmed	Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.	KIR3DL3 KIR2DL4 KIR2DS4	1.30e-05	16	101	3	19897003
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.	KIR3DL3 KIR2DL4 KIR2DS4	1.30e-05	16	101	3	19000141
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.	KIR3DL3 KIR2DL4 KIR2DS4	1.30e-05	16	101	3	20670355
GeneFamily	UNC13 homologs	UNC13B UNC13C UNC13A	2.52e-07	4	73	3	836
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR3DL3 KIR2DL4 KIR2DS4	4.93e-05	18	73	3	620
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	KSR2 KSR1	1.60e-04	5	73	2	1157
GeneFamily	Solute carriers	SLC26A3 SLC4A8 SLCO2B1 SLC13A4 SLC14A1 SLC16A2 SLC14A2 SLC7A10	1.88e-04	395	73	8	752
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A2 ATP1A3	3.33e-04	7	73	2	1208
GeneFamily	Aminoacyl tRNA synthetases, Class I	LARS2 VARS1	2.63e-03	19	73	2	131
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC5 ZDHHC8	4.19e-03	24	73	2	76
GeneFamily	Selenoproteins	SELENON SELENOF	4.54e-03	25	73	2	890
GeneFamily	Autophagy related	ULK1 ULK2	7.83e-03	33	73	2	1022
Coexpression	GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP	SEMA4D PMS2 ACACA PCNX3 DYNC2H1 ZDHHC8 UBE4A	6.40e-06	180	101	7	M357
ToppCell	LV\|World / Chamber and Cluster_Paper	ENOX1 MAST4 SPHKAP PLCL2 ATP1A2 PHACTR1	3.49e-06	180	101	6	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARS2 SPHKAP UNC13C CDYL ATP1A3 UNC79	4.08e-06	185	101	6	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ENOX1 MAST4 SPHKAP PLCL2 ATP1A2 PHACTR1	4.76e-06	190	101	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B ACACA MYO5C MAST4 AOPEP PHACTR1	5.52e-06	195	101	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_9\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	UNC13B MYO1E SELENON MYO5C SLC13A4	8.68e-06	122	101	5	489a01c71882be5a6d71a19d06574698988c20f6
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_9\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UNC13B MYO1E SELENON MYO5C SLC13A4	8.68e-06	122	101	5	7dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2\|TCGA-Pancreas / Sample_Type by Project: Shred V9	KSR2 CFAP65 ATP1A3 UNC79 UNC13A	2.07e-05	146	101	5	bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma\|TCGA-Pancreas / Sample_Type by Project: Shred V9	KSR2 CFAP65 ATP1A3 UNC79 UNC13A	2.07e-05	146	101	5	72c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CDH20 SPHKAP UNC79 UNC13A	3.62e-05	164	101	5	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GHRL KSR2 CFAP65 SERPINA1 UNC13A	3.83e-05	166	101	5	f0912ce0df5ede3bc5e7c99ccfe4decc16c6064e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl-Penk_(Layer_2/3)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC26A3 AVP FCER1A AGMAT	3.84e-05	83	101	4	b683c8496474b0df0042f596c9b0ea5916a2ab15
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SEMA4D PCNX3 SELENON SERPINA1 FCER1A	3.94e-05	167	101	5	820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN LARS2 UNC13C UNC79 DNAH11	4.17e-05	169	101	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPK4 CFAP65 SERPINA1 AGMAT CALML4	4.79e-05	174	101	5	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPK4 CFAP65 SERPINA1 AGMAT CALML4	4.79e-05	174	101	5	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KSR2 MAST4 SPHKAP PCNX1 PHACTR1	5.34e-05	178	101	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KSR2 PLCL2 UNC13C SLC14A2 PHACTR1	5.48e-05	179	101	5	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 ACSS1 OXCT1 DNAH11 PHACTR1	5.63e-05	180	101	5	fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	UNC13B SGMS2 ACACA MAST4 PHACTR1	5.63e-05	180	101	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 ACSS1 OXCT1 DNAH11 PHACTR1	5.63e-05	180	101	5	6763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP UNC13C CDYL ATP1A3 UNC79	5.63e-05	180	101	5	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 UNC79	5.78e-05	181	101	5	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A3 CUBN AGMAT PNPLA3 KHK	5.78e-05	181	101	5	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 UNC79	5.78e-05	181	101	5	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 KHK	6.09e-05	183	101	5	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 KHK	6.09e-05	183	101	5	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	UNC13B ACACA MYO5C MAST4 PHACTR1	6.25e-05	184	101	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 CUBN SLC16A2 KHK CALML4	6.41e-05	185	101	5	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A8 ACSS1 OXCT1 MAST4 UNC13C	6.41e-05	185	101	5	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 CUBN SLC16A2 KHK CALML4	6.41e-05	185	101	5	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.57e-05	186	101	5	73cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARS2 SPHKAP UNC13C CDYL UNC79	6.57e-05	186	101	5	a1ab273b01971d6a892912560d387685dd657179
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARS2 SPHKAP UNC13C CDYL UNC79	6.74e-05	187	101	5	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP UNC13C CDYL ATP1A3 UNC79	6.74e-05	187	101	5	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	6.74e-05	187	101	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	6.74e-05	187	101	5	93c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCN1 SPHKAP UNC13C ATP1A3 DNAH11	6.74e-05	187	101	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGMS2 DYNC2H1 MYO5C SLC16A2 UNC13C	6.74e-05	187	101	5	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	ENOX1 SPHKAP PLCL2 ATP1A2 PHACTR1	6.74e-05	187	101	5	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 KHK	6.91e-05	188	101	5	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	MAST4 SPHKAP PLCL2 ATP1A2 PHACTR1	6.91e-05	188	101	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SPHKAP UNC79 UNC13A	6.91e-05	188	101	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	UNC13B SGMS2 MYO5C MAST4 PHACTR1	6.91e-05	188	101	5	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN MAST4 PNPLA3 KHK	6.91e-05	188	101	5	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	UNC13B SGMS2 SLC4A8 RIPK4 MYO5C	7.09e-05	189	101	5	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ENOX1 MAST4 SPHKAP PLCL2 PHACTR1	7.09e-05	189	101	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	78cc6c28b31de041c24175a98f47da256ecc15a2
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	5c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.27e-05	190	101	5	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E KSR2 UNC13C SLC14A2 PHACTR1	7.45e-05	191	101	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ENOX1 MAST4 SPHKAP PLCL2 PHACTR1	7.45e-05	191	101	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	7.45e-05	191	101	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	7.45e-05	191	101	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1E ACSS1 LARS2 MAST4 VARS1	7.64e-05	192	101	5	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	7.64e-05	192	101	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.64e-05	192	101	5	f7e4509003d71f805b9d4587098e90d2897b6739
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	MAST4 AOPEP SPHKAP PLCL2 PHACTR1	7.64e-05	192	101	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	7.64e-05	192	101	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.64e-05	192	101	5	43beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	UNC13B ACACA MYO5C MAST4 PHACTR1	7.64e-05	192	101	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1E ACSS1 LARS2 MAST4 VARS1	7.64e-05	192	101	5	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.64e-05	192	101	5	705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.82e-05	193	101	5	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	7.82e-05	193	101	5	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E KSR2 UNC13C SLC14A2 PHACTR1	8.02e-05	194	101	5	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DYNC2H1 ADAM15 CNTNAP3 MYO5C CPLANE1	8.02e-05	194	101	5	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B ACACA MYO5C MAST4 PHACTR1	8.02e-05	194	101	5	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E KSR2 UNC13C SLC14A2 PHACTR1	8.02e-05	194	101	5	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B SGMS2 ACACA MAST4 PHACTR1	8.02e-05	194	101	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC26A3 CUBN SERPINA1 KHK CALML4	8.02e-05	194	101	5	fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A3 CUBN SERPINA1 AGMAT KHK	8.41e-05	196	101	5	3cf73ed99f3efa76b632c16a8b98b6b7758ff63f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ADAM15 CNTNAP3 NUDT12 SEPSECS MAST4	8.41e-05	196	101	5	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	PBMC-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GHRL MYO1E ADAM15 FCER1A PHACTR1	8.62e-05	197	101	5	22e4ffb5de483eaf78f14badf3d08db898e3b3dd
ToppCell	PBMC-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GHRL MYO1E ADAM15 FCER1A PHACTR1	8.62e-05	197	101	5	346974c6c5809a3fe88cbf067e2d64c340310a31
ToppCell	PBMC-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GHRL MYO1E ADAM15 FCER1A PHACTR1	8.62e-05	197	101	5	1ae45c1ec3b3f88e0c1f99de58c58b1ec1b968ee
ToppCell	COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease group, lineage and cell class	GHRL MYO1E ADAM15 FCER1A PHACTR1	8.62e-05	197	101	5	843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCell	PBMC-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GHRL MYO1E ADAM15 FCER1A PHACTR1	8.62e-05	197	101	5	f78f44dcd7855c96f148678c1f416075aef71b4e
ToppCell	tumor_Lung-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	IRAG1 SLC14A1 AOPEP PCSK7 ATP1A2	8.83e-05	198	101	5	f540f464118edc0fb809ebcb813d0302e6952253
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KSR2 ATP1A3 UNC79 UNC13A PHACTR1	8.83e-05	198	101	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13B ACACA MYO5C MAST4 PHACTR1	8.83e-05	198	101	5	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13B ACACA MYO5C MAST4 PHACTR1	9.04e-05	199	101	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13B ACACA MYO5C MAST4 PHACTR1	9.04e-05	199	101	5	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13B ACACA MYO5C MAST4 PHACTR1	9.04e-05	199	101	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Unfolded_protein_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	SLC26A3 SLCO2B1 RIPK4 SERPINA1 AGMAT	9.25e-05	200	101	5	12078bc25be67180c0f4b37fef921cdcd1003576
ToppCell	COVID-19-COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease, condition lineage and cell class	GHRL MYO1E ADAM15 FCER1A PHACTR1	9.25e-05	200	101	5	e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACSS1 IRAG1 SLC14A1 ATP1A2 SLC7A10	9.25e-05	200	101	5	7a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSS1 IRAG1 MAST4 SLC14A1 ATP1A2	9.25e-05	200	101	5	01819446deeab9054f5cfe889d53bb49d137dbc0
Drug	Dequalinium dichloride [522-51-0]; Down 200; 7.6uM; PC3; HT_HG-U133A	ADAM15 TM9SF4 SRD5A1 THADA SLC16A2 PCSK7 PCNX1 CALML4	2.77e-06	197	101	8	6296_DN
Drug	glutaconyl-CoA	OXCT1 ATP1A2 ATP1A3	4.67e-06	8	101	3	CID009543049
Disease	epilepsy (implicated_via_orthology)	UNC13B SLC13A4 UNC13C CDYL ATP1A2 ATP1A3 UNC13A	1.09e-06	163	96	7	DOID:1826 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	UNC13B DPF2 UNC13C ATP1A2 ATP1A3 UNC79 UNC13A	3.58e-06	195	96	7	DOID:1574 (implicated_via_orthology)
Disease	ALTERNATING HEMIPLEGIA OF CHILDHOOD 1	ATP1A2 ATP1A3	1.05e-05	2	96	2	C3549447
Disease	alternating hemiplegia of childhood (is_implicated_in)	ATP1A2 ATP1A3	1.05e-05	2	96	2	DOID:0050635 (is_implicated_in)
Disease	monoclonal gammopathy	SGMS2 TMC2 KSR2 SLC14A2	2.73e-05	53	96	4	EFO_0000203
Disease	Alternating hemiplegia of childhood	ATP1A2 ATP1A3	6.26e-05	4	96	2	C0338488
Disease	whole-brain volume	CUBN DNAH11	1.04e-04	5	96	2	EFO_0005089
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A2 ATP1A3	2.18e-04	7	96	2	DOID:0060178 (implicated_via_orthology)
Disease	bipolar disorder (implicated_via_orthology)	CLOCK ATP1A3	2.18e-04	7	96	2	DOID:3312 (implicated_via_orthology)
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	2.90e-04	8	96	2	DOID:0060308 (implicated_via_orthology)
Disease	Congestive heart failure	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C0018802
Disease	Heart failure	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C0018801
Disease	Left-Sided Heart Failure	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C0023212
Disease	Heart Failure, Right-Sided	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C0235527
Disease	Heart Decompensation	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C1961112
Disease	Myocardial Failure	GHRL ACACA AVP ATP1A3	4.67e-04	110	96	4	C1959583
Disease	coronary artery disease	PCNX3 DYNC2H1 KSR2 IRAG1 CLOCK SERPINA1 THADA MAST4 PNPLA3 SLC14A2 UNC13A PHACTR1	4.96e-04	1194	96	12	EFO_0001645
Disease	severe acute respiratory syndrome, COVID-19	PMS2 KSR1 SEPSECS SGMS1 UNC13C OR2Z1 KIR2DS4	6.54e-04	447	96	7	EFO_0000694, MONDO_0100096
Disease	nervous system disease (implicated_via_orthology)	ATP1A2 ATP1A3	6.77e-04	12	96	2	DOID:863 (implicated_via_orthology)
Disease	killer cell immunoglobulin-like receptor 2DL4 measurement	KIR2DL4 KIR2DS4	6.77e-04	12	96	2	EFO_0008197
Disease	facial morphology	SEPSECS SGMS1 SLC7A10	7.74e-04	55	96	3	EFO_0004743
Disease	cirrhosis of liver	SERPINA1 PNPLA3	7.98e-04	13	96	2	EFO_0001422
Disease	Proteinuria	CUBN UNC13C	1.07e-03	15	96	2	HP_0000093
Disease	killer cell immunoglobulin-like receptor 2DS2 measurement	KIR3DL3 KIR2DL4	1.07e-03	15	96	2	EFO_0801746
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	AVP SRD5A1 UGT1A1 OXCT1	1.38e-03	147	96	4	DOID:9352 (biomarker_via_orthology)
Disease	triacylglycerol 60:12 measurement	KSR2 NUDT12	1.38e-03	17	96	2	EFO_0010444
Disease	alcoholic liver cirrhosis	SERPINA1 PNPLA3	1.38e-03	17	96	2	EFO_1000802
Disease	cervical artery dissection	IRAG1 PHACTR1	1.38e-03	17	96	2	EFO_1000059
Disease	migraine disorder, systolic blood pressure	IRAG1 PHACTR1	1.55e-03	18	96	2	EFO_0006335, MONDO_0005277
Disease	hematocrit	RALGAPA1 SEMA4D ACACA IRAG1 SLC14A1 PLCL2 AGMAT PNPLA3 SLC14A2 SLC7A10	1.68e-03	1011	96	10	EFO_0004348
Disease	sucrose liking measurement	SERPINA1 CDH20	1.92e-03	20	96	2	EFO_0010157
Disease	non-high density lipoprotein cholesterol measurement	SLC4A8 ADAM15 UGT1A1 SERPINA1 THADA PNPLA3 SLC7A10 DNAH11	2.29e-03	713	96	8	EFO_0005689
Disease	Bronchiectasis	SERPINA1 DNAH11	2.32e-03	22	96	2	C0006267
Disease	alcoholic liver disease	SPPL3 NUDT12 PNPLA3	2.45e-03	82	96	3	EFO_0008573
Disease	Hodgkins lymphoma	DDX12P AOPEP CPLANE1	2.45e-03	82	96	3	EFO_0000183
Disease	neuroimaging measurement	SEMA4D PDPR KSR2 ZDHHC5 IRAG1 CREB3L4 SERPINA1 THADA MAST4 DNAH11	2.52e-03	1069	96	10	EFO_0004346
Disease	urinary albumin to creatinine ratio	CUBN AOPEP SPHKAP UNC13C	2.82e-03	179	96	4	EFO_0007778
Disease	response to xenobiotic stimulus	ENOX1 SRD5A1 THADA SGMS1	2.99e-03	182	96	4	GO_0009410
Disease	3-hydroxybutyrate measurement	SERPINA1 OXCT1	2.99e-03	25	96	2	EFO_0010982
Disease	cholelithiasis	UGT1A1 SERPINA1 PNPLA3	3.00e-03	88	96	3	EFO_0004799
Disease	eosinophil percentage of leukocytes	ADAM15 A3GALT2 SPPL3 SEPSECS THADA PLCL2 CALML4 SLC7A10	3.02e-03	746	96	8	EFO_0007991
Disease	asthma	SEMA4D SLCO2B1 SPPL3 IRAG1 PLCL2 UNC13C UNC79 SLC7A10	3.15e-03	751	96	8	MONDO_0004979
Disease	migraine disorder, pulse pressure measurement	DYNC2H1 PHACTR1	3.24e-03	26	96	2	EFO_0005763, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKYMCPGVPAVMSTL	UNC13A	886	Q9UPW8
MAPAMESPTLLCVAL	FCER1A	1	P12319
YMPVSPLAVAAMLAC	ACSS1	171	Q9NUB1
KPQILMMGNVSFSCP	CNTNAP3	351	Q9BZ76
FKPAMPRSVVGTACM	CCNH	71	P51946
LMVAMRCLGASPTPG	CALML4	76	Q96GE6
PPTTASRVLSMACLM	SLC7A10	156	Q9NS82
SLPPMAAFCGNMFVE	ADAM15	416	Q13444
AAGAMFLEAIPMSIP	SERPINA1	371	P01009
ATLSGPMCEEPLMGV	EFL1	876	Q7Z2Z2
LPDFCMLMVGSNAGI	GTPBP1	271	O00178
VACMNPMVGSFTINP	DNAH11	2621	Q96DT5
FTPPCQRMGGMVSFR	ACACA	1226	Q13085
TMPMPASTFTIAVGC	AOPEP	331	Q8N6M6
VGALAMGMIFFCSPI	SLC16A2	146	P36021
SIGPMMPVLAGTYRC	KIR2DS4	86	P43632
TCIQPSMISSMALPI	GPR82	6	Q96P67
SAPFGLCPKDMMLTQ	CFAP65	56	Q6ZU64
TMVTKPCGALESPMA	KIAA1109	4721	Q2LD37
NVVLFMGACMSPPHL	KSR2	721	Q6VAB6
MGACMSPPHLAIITS	KSR2	726	Q6VAB6
MGMDLTCPFGISPAC	IRAG1	1	Q9Y6F6
MVVSGFCRSPPVMVA	FLOT1	11	O75955
MLAPCMGLGPAVFTC	RCE1	186	Q9Y256
MALPSTMIIVAVYCP	PCNX1	51	Q96RV3
MVLPPSLMVAGVYCL	PCNX3	51	Q9H6A9
LFCPSGMMSLIGAPR	PCSK7	546	Q16549
LFMGACMNPPHLAII	KSR1	671	Q8IVT5
IGCPMVTIPKMASDF	OR2Z1	71	Q8NG97
PLCAVLVFFVPMMGL	OR51M1	256	Q9H341
FTPDMRCIMGESPAV	PDPR	361	Q8NCN5
MSYVMLPCTLPVESA	PNPLA3	351	Q9NST1
PSLMMGTCRPFAGSL	CSKMT	11	A8MUP2
SMGPMTPALAGTYRC	KIR3DL3	181	Q8N743
GFMLTPVTMSFPFCR	OR2T35	156	Q8NGX2
ICFLPSIIFGMASMV	OXER1	306	Q8TDS5
MICMPVGGPDLSLVS	PHACTR1	246	Q9C0D0
MSMSPTVIILACLGF	KIR2DL4	1	Q99706
MSTPFATVCGDEMPA	CUBN	2991	O60494
CASPATISRMGMIFL	DYNC2H1	2101	Q8NCM8
CFVGLMSMIDPPRAA	ATP1A2	581	P50993
SPDGCSTVMFPKIMG	CDYL	481	Q9Y232
GFRSPSLAICMMTLP	CPLANE1	1921	Q9H799
MPSPGTVCSLLLLGM	GHRL	1	Q9UBU3
GHVMSCSPEAYMLPV	CDH20	601	Q9HBT6
VPALPLLSSLCMAMV	IDI2-AS1	16	Q9NZ38
DNLGRCVVMVGMPFP	DDX12P	806	Q92771
CVVMVGMPFPNIRSA	DDX12P	811	Q92771
LIPMGVCPSATMSQL	A3GALT2	41	U3KPV4
ALSLMIPGDMFAVSP	MAST4	1091	O15021
DNLCFVGLMSMIDPP	ATP1A3	571	P13637
SLLGAPCAFMGSMAP	KHK	51	P50053
TMCISFAVMLPVGNP	SLC13A4	551	Q9UKG4
SICVPGFDPSLNMMT	ENOX1	71	Q8TC92
AFMVPDSCMVSELPF	CREB3L4	146	Q8TEY5
KPQILMMGNVSFSCP	CNTNAP3B	351	Q96NU0
TLMGFCIAMVVSFLP	OR2AT4	201	A6NND4
SPGMSLVMAPIACLL	RUNDC1	446	Q96C34
VFMMCIPPPNVTGSL	VARS1	336	P26640
SEAMPPLCGLASMEL	SPHKAP	596	Q2M3C7
ALSMGPFVPFIMRCG	THADA	1341	Q6YHU6
VPGKDCLTPVMAVNM	LARS2	336	Q15031
LQPCTSVMPMLSAAF	NBR1	361	Q14596
LMQCMLAVSPRFLGP	PLCL2	956	Q9UPR0
YVVAMLCGLPRPLMS	SHPK	181	Q9UHJ6
SPEFVARPVGVCSMM	AGMAT	46	Q9BSE5
PMPSSLMIGCLALAV	NUDT12	391	Q9BQG2
SVGPFPILSMMVGLA	SLC26A3	126	P40879
CSVFMTAILKFIPMP	SLC4A8	891	Q2Y0W8
STGCDFAVSPKLMPM	OXCT1	501	P55809
VMFGTAMAFAPIPRI	SEMA4D	16	Q92854
CITMYVTTLPVPGMH	SGMS2	171	Q8NHU3
AVGMNFLHCMAPPLL	RIPK4	126	P57078
APVACGAVMVPSTML	CLOCK	716	O15516
SIVATTMPIPCGGFM	CLCN1	471	P35523
TMPIPCGGFMPVFVL	CLCN1	476	P35523
CGIRMTSSNMPLPAS	TMPRSS11F	186	Q6ZWK6
PMSGGPAMLTSQVCE	RALGAPA1	1521	Q6GYQ0
KYMCPGVPAVMSTLL	UNC13C	1431	Q8NB66
SGAVPFPTMVALLCM	TM9SF4	441	Q92544
VCLSSMAAGMAIFLP	SLCO2B1	381	O94956
MGLCVAMIAFVRLPS	SPPL3	171	Q8TCT6
MVAMAAGPSGCLVPA	SELENOF	1	O60613
FPVEMMICLPNGTVV	SELENON	521	Q9NZV5
MPDTMLPACFLGLLA	AVP	1	P01185
SICNGVPMVMMPLFG	UGT1A1	381	P22309
SGHPSCLQFTPVMMA	DPF2	301	Q92785
RCITMYVTTLPVPGM	SGMS1	226	Q86VZ5
KYMCPGVPAVMSTLL	UNC13B	811	O14795
LLLPVCAMSMTCPIF	SLC14A1	146	Q13336
FLPPALCDMTGTSLM	SLC35F6	91	Q8N357
LIFMLSDSPGVMCRP	PMS2	786	P54278
AATLCGSPMYMAPEV	ULK2	171	Q8IYT8
TMAVMCVAGLFFIPV	ZDHHC5	186	Q9C0B5
TMAVMCVAGLFFIPV	ZDHHC8	186	Q9ULC8
PMPLLACTMAIMFCT	SRD5A1	111	P18405
PMATGMSLTLCFLTL	SEPSECS	141	Q9HD40
IMSTLMCDPVVLPSS	UBE4A	996	Q14139
EVEIVMSLLGMFCPP	TMC2	471	Q8TDI7
MSLLGMFCPPLFETI	TMC2	476	Q8TDI7
MMSHPCVSLLGVPVL	ZNF275	1	Q9NSD4
PVIIMSMSCPILSSA	SLC14A2	671	Q15849
LCGSPMYMAPEVIMS	ULK1	181	O75385
ASNLTVPMTMCLFPV	UNC79	61	Q9P2D8
PPGIMSILDDVCATM	MYO1E	456	Q12965
MIPGLPAHILFMCVR	MYO5C	1391	Q9NQX4