Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	LRR domain binding	ZXDC CRX STK11 ATF4	5.49e-06	22	108	4	GO:0030275
GeneOntologyMolecularFunction	Notch binding	NCOR2 EGFL7 NOTCH1 NOTCH4	1.29e-05	27	108	4	GO:0005112
GeneOntologyMolecularFunction	SAM domain binding	L3MBTL1 SAMD11	8.66e-05	3	108	2	GO:0032093
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE1 SLURP2 SPDYE16	4.09e-04	27	108	3	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE1 SLURP2 SPDYE16	4.57e-04	28	108	3	GO:0099602
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL9A1 COL19A1 LAMA2 SSPOP HMCN2 LTBP4	5.56e-04	188	108	6	GO:0005201
GeneOntologyMolecularFunction	chromatin binding	TOX RBPJL CRX NCOR2 L3MBTL1 SAMD11 BHLHE22 ATF4 AJUBA ZNHIT1 NOTCH1 HR	6.53e-04	739	108	12	GO:0003682
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	MEF2B RBPJL SOX17 RAX CRX ZNF668 NKX2-8 ATF4 NOTCH1 NOTCH4	9.18e-04	560	108	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	MEF2B RBPJL SOX17 RAX CRX ZNF668 NKX2-8 ATF4 NOTCH1 NOTCH4	9.95e-04	566	108	10	GO:0001216
GeneOntologyBiologicalProcess	venous blood vessel morphogenesis	EPHB4 CHRD NOTCH1 NOTCH4	4.90e-07	13	108	4	GO:0048845
GeneOntologyBiologicalProcess	positive regulation of aorta morphogenesis	EPHB4 NOTCH1 NOTCH4	5.56e-07	4	108	3	GO:1903849
GeneOntologyBiologicalProcess	regulation of aorta morphogenesis	EPHB4 NOTCH1 NOTCH4	2.76e-06	6	108	3	GO:1903847
GeneOntologyBiologicalProcess	venous blood vessel development	EPHB4 CHRD NOTCH1 NOTCH4	3.23e-06	20	108	4	GO:0060841
GeneOntologyBiologicalProcess	positive regulation of artery morphogenesis	EPHB4 NOTCH1 NOTCH4	1.15e-05	9	108	3	GO:1905653
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	PSEN2 IRF7 ZFPM1 OTUD7B NCOR2 ZNF668 L3MBTL1 WTIP SAMD11 BHLHE22 SKOR1 ATF4 VGLL4 AJUBA ZNHIT1 SGF29 NOTCH1 NOTCH3 NOTCH4 HR	3.46e-05	1399	108	20	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	PSEN2 IRF7 ZFPM1 OTUD7B NCOR2 ZNF668 L3MBTL1 WTIP SAMD11 BHLHE22 SKOR1 ATF4 VGLL4 AJUBA ZNHIT1 SGF29 NOTCH1 NOTCH3 NOTCH4 HR	3.99e-05	1413	108	20	GO:1902679
GeneOntologyBiologicalProcess	cell fate commitment	PSEN2 TOX SOX17 ZFPM1 BHLHE22 CHRD NOTCH1 NOTCH3 NOTCH4	7.22e-05	338	108	9	GO:0045165
GeneOntologyBiologicalProcess	regulation of artery morphogenesis	EPHB4 NOTCH1 NOTCH4	9.00e-05	17	108	3	GO:1905651
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	MEF2B TOX RBPJL SOX17 IER5 IRF7 CYTL1 ZFPM1 RAX CRX BCL2L12 ZNF668 NKX2-8 BHLHE22 ATF4 ZNHIT1 NOTCH1 NOTCH3 NOTCH4	1.02e-04	1390	108	19	GO:0045944
GeneOntologyBiologicalProcess	artery morphogenesis	EPHB4 CHRD NOTCH1 NOTCH3 NOTCH4	1.23e-04	92	108	5	GO:0048844
GeneOntologyBiologicalProcess	negative regulation of hippo signaling	WTIP VGLL4 AJUBA	2.00e-04	22	108	3	GO:0035331
GeneOntologyBiologicalProcess	forebrain development	PSEN2 TOX RAX NCOR2 BLOC1S6 KCNA3 BHLHE22 CHRD NOTCH1 NOTCH3	2.49e-04	489	108	10	GO:0030900
GeneOntologyBiologicalProcess	mitral valve formation	ZFPM1 NOTCH1	2.69e-04	5	108	2	GO:0003192
GeneOntologyBiologicalProcess	animal organ morphogenesis	ALX3 EPHB4 COL9A1 PSEN2 SOX17 LAMA2 ZFPM1 CRX HOXA3 NCOR2 SAMD11 BHLHE22 ACP4 ATF4 ATG9A MYO15A NOTCH1	3.12e-04	1269	108	17	GO:0009887
Domain	Notch	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	IPR008297
Domain	NODP	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	IPR010660
Domain	NOD	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	PF06816
Domain	NOD	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	SM01338
Domain	NODP	NOTCH1 NOTCH3 NOTCH4	6.49e-07	4	103	3	SM01339
Domain	LNR	NOTCH1 NOTCH3 NOTCH4	1.62e-06	5	103	3	PS50258
Domain	EGF_2	EPHB4 LAMA2 SSPOP HMCN2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	2.07e-06	265	103	10	PS01186
Domain	Growth_fac_rcpt_	EPHB4 HMCN2 EGFL7 LTBP4 RSPO1 NOTCH1 NOTCH3 NOTCH4	2.40e-06	156	103	8	IPR009030
Domain	Notch_dom	NOTCH1 NOTCH3 NOTCH4	5.61e-06	7	103	3	IPR000800
Domain	Notch	NOTCH1 NOTCH3 NOTCH4	5.61e-06	7	103	3	PF00066
Domain	NL	NOTCH1 NOTCH3 NOTCH4	5.61e-06	7	103	3	SM00004
Domain	EGF_CA	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	7.99e-06	86	103	6	PF07645
Domain	EGF_1	LAMA2 SSPOP HMCN2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	1.18e-05	255	103	9	PS00022
Domain	EGF-like_CS	EPHB4 LAMA2 HMCN2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	1.42e-05	261	103	9	IPR013032
Domain	EGF_Ca-bd_CS	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	1.60e-05	97	103	6	IPR018097
Domain	EGF_CA	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	1.80e-05	99	103	6	PS01187
Domain	ASX_HYDROXYL	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	1.90e-05	100	103	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	2.65e-05	106	103	6	IPR000152
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	3.46e-05	12	103	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	3.46e-05	12	103	3	IPR027970
Domain	EGF_3	SSPOP HMCN2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	4.75e-05	235	103	8	PS50026
Domain	EGF_CA	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	5.86e-05	122	103	6	SM00179
Domain	EGF-like_Ca-bd_dom	HMCN2 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	6.41e-05	124	103	6	IPR001881
Domain	EGF-like_dom	LAMA2 HMCN2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	7.13e-05	249	103	8	IPR000742
Domain	DUF3454	NOTCH1 NOTCH3	9.00e-05	3	103	2	PF11936
Domain	DUF3454_notch	NOTCH1 NOTCH3	9.00e-05	3	103	2	IPR024600
Domain	Topo_IA_cen_sub2	RBBP6 TOP3A	9.00e-05	3	103	2	IPR013825
Domain	DUF3454	NOTCH1 NOTCH3	9.00e-05	3	103	2	SM01334
Domain	EGF	LAMA2 ADAM33 EGFL7 LTBP4 NOTCH1 NOTCH3 NOTCH4	3.25e-04	235	103	7	SM00181
Domain	EGF_extracell	ADAM33 EGFL7 NOTCH1 NOTCH3	3.36e-04	60	103	4	IPR013111
Domain	EGF_2	ADAM33 EGFL7 NOTCH1 NOTCH3	3.36e-04	60	103	4	PF07974
Domain	Gphrmn_rcpt_fam	LGR5 LGR6	4.45e-04	6	103	2	IPR002131
Domain	hEGF	NOTCH1 NOTCH3 NOTCH4	4.83e-04	28	103	3	PF12661
Domain	VWFC_1	KCP SSPOP CHRD	1.02e-03	36	103	3	PS01208
Domain	VWC	KCP SSPOP CHRD	1.19e-03	38	103	3	SM00214
Domain	VWFC_2	KCP SSPOP CHRD	1.19e-03	38	103	3	PS50184
Domain	SAM	EPHB4 ARAP3 L3MBTL1 SAMD11	1.43e-03	88	103	4	SM00454
Domain	VWF_dom	KCP SSPOP CHRD	1.60e-03	42	103	3	IPR001007
Domain	Spy1	SPDYE1 SPDYE16	1.60e-03	11	103	2	PF11357
Domain	Speedy	SPDYE1 SPDYE16	1.60e-03	11	103	2	IPR020984
Domain	SAM_DOMAIN	EPHB4 ARAP3 L3MBTL1 SAMD11	1.89e-03	95	103	4	PS50105
Domain	SAM	EPHB4 ARAP3 L3MBTL1 SAMD11	2.04e-03	97	103	4	IPR001660
Domain	Unchr_dom_Cys-rich	KCP SSPOP	2.26e-03	13	103	2	IPR014853
Domain	C8	KCP SSPOP	2.26e-03	13	103	2	SM00832
Domain	OTU	OTUD7B ALG13	2.26e-03	13	103	2	PF02338
Domain	TIL_dom	KCP SSPOP	2.62e-03	14	103	2	IPR002919
Domain	-	EPHB4 ARAP3 L3MBTL1 SAMD11	2.82e-03	106	103	4	1.10.150.50
Domain	OTU	OTUD7B ALG13	3.02e-03	15	103	2	PS50802
Domain	OTU_dom	OTUD7B ALG13	3.02e-03	15	103	2	IPR003323
Domain	VWD	KCP SSPOP	3.44e-03	16	103	2	SM00216
Domain	VWF_type-D	KCP SSPOP	3.44e-03	16	103	2	IPR001846
Domain	VWFD	KCP SSPOP	3.44e-03	16	103	2	PS51233
Domain	VWD	KCP SSPOP	3.44e-03	16	103	2	PF00094
Domain	Homeobox_CS	ALX3 RAX CRX HOXA3 NKX2-8	3.70e-03	186	103	5	IPR017970
Domain	EMI	SSPOP EGFL7	3.88e-03	17	103	2	PS51041
Domain	SAM/pointed	EPHB4 ARAP3 L3MBTL1 SAMD11	4.02e-03	117	103	4	IPR013761
Domain	Laminin_G	COL9A1 COL19A1 LAMA2	4.03e-03	58	103	3	IPR001791
Domain	-	ALX3 RAX CRX HOXA3 NCOR2 NKX2-8	4.81e-03	283	103	6	1.10.10.60
Domain	VWC_out	KCP SSPOP	4.84e-03	19	103	2	SM00215
Pathway	WP_NOTCH_SIGNALING_WP268	PSEN2 RBPJL NCOR2 NOTCH1 NOTCH3 NOTCH4	1.09e-07	45	73	6	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	PSEN2 RBPJL NCOR2 NOTCH1 NOTCH3 NOTCH4	1.24e-07	46	73	6	MM15971
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	PSEN2 RBPJL NCOR2 NOTCH1 NOTCH3 NOTCH4	1.42e-07	47	73	6	M7946
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION	PSEN2 NOTCH1 NOTCH3 NOTCH4	2.12e-07	11	73	4	M47865
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380	RBPJL NOTCH1 NOTCH3 NOTCH4	3.17e-07	12	73	4	M47532
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381	RBPJL NOTCH1 NOTCH3 NOTCH4	3.17e-07	12	73	4	M47533
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	RBPJL NOTCH1 NOTCH3 NOTCH4	4.57e-07	13	73	4	M47423
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382	RBPJL NOTCH1 NOTCH3 NOTCH4	4.57e-07	13	73	4	M47534
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH1 NOTCH3 NOTCH4	1.32e-06	5	73	3	M27411
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	NOTCH1 NOTCH3 NOTCH4	1.32e-06	5	73	3	MM14733
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO	LGR5 ZNRF3 LGR6 RSPO1	2.42e-06	19	73	4	M47833
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH1 NOTCH3 NOTCH4	2.64e-06	6	73	3	M27068
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 ZNRF3 LGR6 RSPO1	3.71e-06	21	73	4	M27401
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	PSEN2 ZFPM1 NCOR2 NOTCH1 NOTCH3 NOTCH4	4.01e-06	82	73	6	MM15922
Pathway	REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	NOTCH1 NOTCH3 NOTCH4	4.59e-06	7	73	3	MM14734
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	NCOR2 NOTCH1 NOTCH3 NOTCH4	5.44e-06	23	73	4	MM14954
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	PSEN2 NOTCH1 NOTCH3 NOTCH4	1.06e-05	27	73	4	M39545
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	NCOR2 NOTCH1 NOTCH3 NOTCH4	1.23e-05	28	73	4	M6177
Pathway	PID_NOTCH_PATHWAY	SSPOP NCOR2 NOTCH1 NOTCH3 NOTCH4	1.31e-05	59	73	5	M17
Pathway	WP_NOTCH_SIGNALING_WP61	PSEN2 NCOR2 NOTCH1 NOTCH3 NOTCH4	1.54e-05	61	73	5	M39540
Pathway	WP_NEOVASCULARIZATION_PROCESSES	EPHB4 NOTCH1 NOTCH3 NOTCH4	3.84e-05	37	73	4	M39506
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	RBPJL NOTCH1 NOTCH4	7.11e-05	16	73	3	M47424
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	NOTCH1 NOTCH3 NOTCH4	1.03e-04	18	73	3	M614
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 ZNRF3 RSPO1	1.43e-04	20	73	3	MM15155
Pathway	KEGG_DORSO_VENTRAL_AXIS_FORMATION	NOTCH1 NOTCH3 NOTCH4	2.49e-04	24	73	3	M11190
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	SSPOP NOTCH1 NOTCH3 NOTCH4	4.20e-04	68	73	4	M27303
Pathway	WP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT	NOTCH1 NOTCH3 NOTCH4	7.10e-04	34	73	3	M39390
Pathway	REACTOME_NONCANONICAL_ACTIVATION_OF_NOTCH3	PSEN2 NOTCH3	7.26e-04	8	73	2	M27887
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	SSPOP NOTCH1 NOTCH3 NOTCH4 ALG13	8.65e-04	143	73	5	M27275
Pathway	REACTOME_SIGNALING_BY_NOTCH	NOTCH1 NOTCH3 NOTCH4	1.07e-03	39	73	3	MM14604
Pathway	WP_PTF1A_RELATED_REGULATORY_PATHWAY	RBPJL NOTCH1	1.41e-03	11	73	2	M39548
Pathway	REACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	PSEN2 NOTCH4	1.41e-03	11	73	2	M27882
Pathway	REACTOME_DISEASES_OF_METABOLISM	SSPOP CSF2RB NOTCH1 NOTCH3 NOTCH4 ALG13	1.85e-03	250	73	6	M27554
Pathway	WP_PTF1A_RELATED_REGULATORY_PATHWAY	RBPJL NOTCH1	1.99e-03	13	73	2	MM15904
Pathway	REACTOME_SIGNALING_BY_NOTCH3	PSEN2 NOTCH1 NOTCH3	2.07e-03	49	73	3	M618
Pubmed	RBP-L, a transcription factor related to RBP-Jkappa.	RBPJL NOTCH1 NOTCH3 NOTCH4	1.47e-09	6	111	4	9111338
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	1.47e-09	6	111	4	20850414
Pubmed	Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.	EGFL7 NOTCH1 NOTCH3 NOTCH4	1.47e-09	6	111	4	19503073
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	1.47e-09	6	111	4	25930072
Pubmed	Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.	PSEN2 NOTCH1 NOTCH3 NOTCH4	3.41e-09	7	111	4	11518718
Pubmed	Notch receptor expression in human brain arteriovenous malformations.	NOTCH1 NOTCH3 NOTCH4	3.16e-08	3	111	3	25846406
Pubmed	The expression of Sox17 identifies and regulates haemogenic endothelium.	SOX17 HOXA3 NOTCH1 NOTCH4	3.19e-08	11	111	4	23604320
Pubmed	RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.	LGR5 ZNRF3 LGR6 RSPO1	4.77e-08	12	111	4	29769720
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPHB4 ZXDC FBRS ZFPM1 CCDC142 SCAF1 NCOR2 ARAP3 ZNRF3 SEC16A ATG9A LTBP4 NOTCH1 ABCC10 TOP3A ZNF687 HR	8.34e-08	1105	111	17	35748872
Pubmed	Cell-fate transition and determination analysis of mouse male germ cells throughout development.	ZXDC NOTCH1 NOTCH3 NOTCH4	9.60e-08	14	111	4	34824237
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	24145721
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	20069356
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	28669409
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	11401408
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	8898100
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	17920003
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	28061457
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	24151014
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	10194420
Pubmed	Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	11459941
Pubmed	Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	18184405
Pubmed	Notch signaling in the mammalian central nervous system: insights from mouse mutants.	NOTCH1 NOTCH3 NOTCH4	1.26e-07	4	111	3	15917835
Pubmed	Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.	EPHB4 NOTCH1 NOTCH3 NOTCH4	2.90e-07	18	111	4	18093989
Pubmed	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.	NOTCH1 NOTCH3 NOTCH4	3.15e-07	5	111	3	11101851
Pubmed	Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.	NOTCH1 NOTCH3 NOTCH4	3.15e-07	5	111	3	20554499
Pubmed	Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.	NOTCH1 NOTCH3 NOTCH4	3.15e-07	5	111	3	21124806
Pubmed	Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).	NOTCH1 NOTCH3 NOTCH4	3.15e-07	5	111	3	23675950
Pubmed	Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.	NOTCH1 NOTCH3 NOTCH4	3.15e-07	5	111	3	15882997
Pubmed	Sox17 is indispensable for acquisition and maintenance of arterial identity.	EPHB4 SOX17 NOTCH1 NOTCH4	4.58e-07	20	111	4	24153254
Pubmed	Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.	EGFL7 NOTCH1 NOTCH3 NOTCH4	5.64e-07	21	111	4	28656980
Pubmed	Characterization of Notch receptor expression in the developing mammalian heart and liver.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	12244553
Pubmed	Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.	PSEN2 NOTCH1 NOTCH3	6.28e-07	6	111	3	19573812
Pubmed	Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	7835890
Pubmed	Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	18299578
Pubmed	Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	15019995
Pubmed	Notch controls the magnitude of T helper cell responses by promoting cellular longevity.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	22615412
Pubmed	Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	20870902
Pubmed	A study on Notch signaling in human breast cancer.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	17822320
Pubmed	The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.	NCOR2 NOTCH1 NOTCH3	6.28e-07	6	111	3	11404076
Pubmed	Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.	LGR5 ZNRF3 RSPO1	6.28e-07	6	111	3	24225776
Pubmed	Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.	LGR5 LGR6 RSPO1	6.28e-07	6	111	3	21727895
Pubmed	Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.	NOTCH1 NOTCH3 NOTCH4	6.28e-07	6	111	3	21991352
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	EGFL7 NOTCH1 NOTCH3 NOTCH4	8.30e-07	23	111	4	36239412
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	9.94e-07	24	111	4	32212159
Pubmed	Human ligands of the Notch receptor.	NOTCH1 NOTCH3 NOTCH4	1.10e-06	7	111	3	10079256
Pubmed	Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.	LGR5 LGR6 RSPO1	1.10e-06	7	111	3	37651925
Pubmed	The distribution of Notch receptors and their ligands during articular cartilage development.	NOTCH1 NOTCH3 NOTCH4	1.10e-06	7	111	3	12846471
Pubmed	Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.	LGR5 ZNRF3 RSPO1	1.10e-06	7	111	3	29752411
Pubmed	Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis.	EPHB4 NOTCH1 NOTCH4	1.10e-06	7	111	3	18952909
Pubmed	Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.	PSEN2 NOTCH1 NOTCH3	1.10e-06	7	111	3	16169548
Pubmed	Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.	SOX17 NOTCH1 NOTCH3 NOTCH4	1.39e-06	26	111	4	25446530
Pubmed	Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.	RAX CRX BHLHE22 NOTCH1	1.63e-06	27	111	4	24148613
Pubmed	R-spondins/Lgrs expression in tooth development.	LGR5 LGR6 RSPO1	1.75e-06	8	111	3	24616052
Pubmed	Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.	NOTCH1 NOTCH3 NOTCH4	1.75e-06	8	111	3	9858718
Pubmed	Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.	NOTCH1 NOTCH3 NOTCH4	1.75e-06	8	111	3	22156581
Pubmed	Notch1 and Jagged1 expression by the developing pulmonary vasculature.	NOTCH1 NOTCH3 NOTCH4	1.75e-06	8	111	3	12242716
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	LGR5 NOTCH1 NOTCH3 NOTCH4	2.19e-06	29	111	4	21402740
Pubmed	R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.	LGR5 ZNRF3 LGR6 RSPO1	2.53e-06	30	111	4	32324134
Pubmed	Notch signaling represses p63 expression in the developing surface ectoderm.	PSEN2 NOTCH1 NOTCH4	2.62e-06	9	111	3	23924630
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	NOTCH1 NOTCH3 NOTCH4	2.62e-06	9	111	3	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	NOTCH1 NOTCH3 NOTCH4	2.62e-06	9	111	3	16245338
Pubmed	Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.	NOTCH1 NOTCH3 NOTCH4	2.62e-06	9	111	3	12370315
Pubmed	Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.	PSEN2 NOTCH1 NOTCH3	2.62e-06	9	111	3	18507503
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SFSWAP RBBP6 LSG1 FBRS OAS3 SCAF1 NCOR2 HMCN2 ZNRF3 SEC16A PIP4K2B SGF29 LTBP4 ZNF687 ALG13	2.75e-06	1116	111	15	31753913
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	NOTCH1 NOTCH3 NOTCH4	3.74e-06	10	111	3	23665443
Pubmed	Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.	NOTCH1 NOTCH3 NOTCH4	3.74e-06	10	111	3	14766969
Pubmed	gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.	PSEN2 NOTCH1 NOTCH3	3.74e-06	10	111	3	15525534
Pubmed	Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.	NOTCH1 NOTCH3 NOTCH4	3.74e-06	10	111	3	33915108
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	SSPOP SCAF1 ZNRF3 CHRD PIP4K2B ADAM33 EGFL7 AJUBA LTBP4 NOTCH1 ALG13	4.16e-06	608	111	11	16713569
Pubmed	A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.	NOTCH1 NOTCH3 NOTCH4	5.12e-06	11	111	3	9187150
Pubmed	Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.	NOTCH1 NOTCH3 NOTCH4	5.12e-06	11	111	3	16607638
Pubmed	Coexpression of Cux-1 and Notch signaling pathway components during kidney development.	NOTCH1 NOTCH3 NOTCH4	5.12e-06	11	111	3	15499562
Pubmed	Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.	NOTCH1 NOTCH3 NOTCH4	5.12e-06	11	111	3	10878608
Pubmed	Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.	NOTCH1 NOTCH3 NOTCH4	5.12e-06	11	111	3	12866128
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL9A1 COL19A1 RAX CHRD RSPO1 NOTCH1 NOTCH3	5.29e-06	210	111	7	16537572
Pubmed	Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7.	EGFL7 NOTCH1 NOTCH4	6.82e-06	12	111	3	20947685
Pubmed	Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.	NOTCH1 NOTCH3 NOTCH4	6.82e-06	12	111	3	15465494
Pubmed	Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells.	EPHB4 NOTCH1 NOTCH4	6.82e-06	12	111	3	36082581
Pubmed	Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.	NOTCH1 NOTCH3 NOTCH4	6.82e-06	12	111	3	10952889
Pubmed	A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.	NOTCH1 NOTCH3 NOTCH4	8.84e-06	13	111	3	32929274
Pubmed	Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.	NOTCH1 NOTCH3 NOTCH4	8.84e-06	13	111	3	11578869
Pubmed	Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.	NOTCH1 NOTCH3 NOTCH4	8.84e-06	13	111	3	20558824
Pubmed	Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer.	LGR5 LGR6	1.01e-05	2	111	2	22002312
Pubmed	Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.	LGR5 RSPO1	1.01e-05	2	111	2	23809763
Pubmed	Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.	NOTCH1 NOTCH4	1.01e-05	2	111	2	24305720
Pubmed	Notch signaling in cancer.	NOTCH1 NOTCH4	1.01e-05	2	111	2	12496471
Pubmed	Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.	NOTCH3 NOTCH4	1.01e-05	2	111	2	33665264
Pubmed	Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.	NOTCH1 NOTCH4	1.01e-05	2	111	2	23389453
Pubmed	Identification of the Photoreceptor Transcriptional Co-Repressor SAMD11 as Novel Cause of Autosomal Recessive Retinitis Pigmentosa.	CRX SAMD11	1.01e-05	2	111	2	27734943
Pubmed	Notch signaling: from the outside in.	NOTCH1 NOTCH4	1.01e-05	2	111	2	11112321
Pubmed	Thymosin beta4 induces angiogenesis through Notch signaling in endothelial cells.	NOTCH1 NOTCH4	1.01e-05	2	111	2	23749167
Pubmed	Selective Targeting and Eradication of LGR5+ Cancer Stem Cells Using RSPO-Conjugated Doxorubicin Liposomes.	LGR5 RSPO1	1.01e-05	2	111	2	29695632
Pubmed	HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.	LGR5 RSPO1	1.01e-05	2	111	2	29079780
Pubmed	Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.	NOTCH3 NOTCH4	1.01e-05	2	111	2	17696940
Pubmed	Notch-1 and notch-4 receptors as prognostic markers in breast cancer.	NOTCH1 NOTCH4	1.01e-05	2	111	2	20444726
Pubmed	Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.	ZNRF3 RSPO1	1.01e-05	2	111	2	24349440
Pubmed	A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.	NOTCH1 NOTCH3	1.01e-05	2	111	2	21191019
Interaction	EGFL7 interactions	KLRG2 PLD3 ADAM33 EGFL7 NOTCH1 NOTCH3 NOTCH4	1.42e-07	77	104	7	int:EGFL7
Interaction	NOTCH4 interactions	PSEN2 EGFL7 NOTCH3 NOTCH4	3.74e-06	21	104	4	int:NOTCH4
Interaction	NOTCH3 interactions	PSEN2 ADAM33 EGFL7 NOTCH1 NOTCH3 NOTCH4	2.64e-05	113	104	6	int:NOTCH3
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	1.64e-04	8	112	2	chr9q12
GeneFamily	Sterile alpha motif domain containing	EPHB4 ARAP3 L3MBTL1 SAMD11	3.00e-04	88	66	4	760
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	ZFPM1 L3MBTL1	1.52e-03	16	66	2	66
GeneFamily	OTU domain containing	OTUD7B ALG13	1.72e-03	17	66	2	669
Coexpression	NABA_CORE_MATRISOME	COL9A1 COL19A1 LAMA2 KCP SSPOP HMCN2 LTBP4 RSPO1	1.77e-05	270	109	8	MM17057
Coexpression	NABA_CORE_MATRISOME	COL9A1 COL19A1 LAMA2 KCP SSPOP HMCN2 LTBP4 RSPO1	2.02e-05	275	109	8	M5884
Coexpression	HALLMARK_WNT_BETA_CATENIN_SIGNALING	PSEN2 NCOR2 NOTCH1 NOTCH4	2.80e-05	42	109	4	M5895
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	NOTCH1 NOTCH3 NOTCH4	3.77e-05	16	109	3	MM1296
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	NOTCH1 NOTCH3 NOTCH4	3.77e-05	16	109	3	M2207
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	2.95e-07	174	112	7	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCP HCN2 SSPOP FAM162B KCNA3 AJUBA NOTCH3	3.31e-07	177	112	7	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCP HCN2 SSPOP FAM162B KCNA3 AJUBA NOTCH3	3.31e-07	177	112	7	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IER5 IRF7 SLFN5 CSF2RB EGFL7 LTBP4	4.00e-07	182	112	7	ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IER5 IRF7 SLFN5 CSF2RB EGFL7 LTBP4	4.00e-07	182	112	7	97a805783a1f2b055c21307db250e3688674eff3
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PSEN2 SOX17 CYTL1 ARAP3 EGFL7 NOTCH4	4.63e-07	186	112	7	b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PSEN2 SOX17 CYTL1 ARAP3 EGFL7 NOTCH4	4.63e-07	186	112	7	8a8ed1502542d4895cba3fd5d534256206578716
ToppCell	droplet-Pancreas-Exocrine-24m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	4.80e-07	187	112	7	a178b1fed80a0bf83aedb6262493ee17374734b5
ToppCell	droplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	4.80e-07	187	112	7	e60cbccf5842f25123fd34b9475759b7424b32e9
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX17 CYTL1 VGLL4 EGFL7 LTBP4 NOTCH1 NOTCH4	4.80e-07	187	112	7	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	droplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	4.80e-07	187	112	7	2b8eda2812be0be68a6f01aa4038925d3d5b1e65
ToppCell	droplet-Kidney-nan-18m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IRF7 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	4.98e-07	188	112	7	ca3be1942b179b512ab242acded31f1e3748c753
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 CSF2RB EGFL7 LTBP4 NOTCH4	5.16e-07	189	112	7	8ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 CSF2RB EGFL7 LTBP4 NOTCH4	5.16e-07	189	112	7	403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 SOX17 CYTL1 SLFN5 EGFL7 NOTCH1 NOTCH4	5.16e-07	189	112	7	1e1afa66b32ae752c0a42b02b80f10205464569c
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PSEN2 SOX17 CYTL1 ARAP3 EGFL7 NOTCH4	5.16e-07	189	112	7	2e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	5.34e-07	190	112	7	b7fc451e160e31dc898b122de844b501f587db67
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IRF7 SLFN5 LGR5 EGFL7 LTBP4 NOTCH4	5.34e-07	190	112	7	cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IRF7 SLFN5 LGR5 EGFL7 LTBP4 NOTCH4	5.34e-07	190	112	7	5bf3d0beee69879c95265d07fba023626a7cc808
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	5.34e-07	190	112	7	83cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	5.34e-07	190	112	7	5f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 SOX17 CYTL1 SLFN5 EGFL7 LTBP4 NOTCH1	5.54e-07	191	112	7	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB4 TOX SOX17 CYTL1 EGFL7 LTBP4 NOTCH1	5.54e-07	191	112	7	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 CYTL1 SLFN5 LGR5 EGFL7 LTBP4 NOTCH4	5.73e-07	192	112	7	c0498baa2556e1597c00df2e75efadeb14bd34ef
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 SLFN5 ARAP3 EGFL7 LTBP4	5.73e-07	192	112	7	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 CYTL1 SLFN5 LGR5 EGFL7 LTBP4 NOTCH4	5.73e-07	192	112	7	cb906b10cad76e978c5c0b966215368ebef30e51
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 SLFN5 ARAP3 EGFL7 LTBP4	5.73e-07	192	112	7	bcd8876235be503186f119653b39476488c0fa15
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LGR5 FAM162B ADAM33 LGR6 FRMPD3 AJUBA NOTCH3	5.73e-07	192	112	7	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	facs-Kidney-nan-3m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH1	6.15e-07	194	112	7	5fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCell	facs-Kidney-nan-3m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH1	6.15e-07	194	112	7	04df35246287815bdd28adaf885bdb98cf49524e
ToppCell	facs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH1	6.15e-07	194	112	7	90928d6c96c6304ae35dcc0275f7889de93da100
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	6.36e-07	195	112	7	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP2 COL9A1 NKX2-8 HMCN2 AJUBA ZNF687	8.81e-07	128	112	6	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAS3 IER5 IRF7 SLFN5 MYO15A RSPO1	1.68e-06	143	112	6	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAS3 IER5 IRF7 SLFN5 MYO15A RSPO1	1.68e-06	143	112	6	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	Bronchus_Control_(B.)-Endothelial-TX-Endothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	EPHB4 BCL2L12 ZFYVE19 EGFL7 AJUBA	1.93e-06	81	112	5	a1193b2cfb84a6b6593779fef5f54a61567a12d7
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KCNA3 L3MBTL1 BHLHE22 SKOR1 ACP4 NALF2	2.14e-06	149	112	6	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK\|Thalamus / BrainAtlas - Mouse McCarroll V32	FKBP6 SOX17 IRF7 ARAP3 EGFL7 NOTCH4	2.69e-06	155	112	6	fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 ARAP3 MOV10L1 EGFL7 NOTCH1 NOTCH4	3.59e-06	163	112	6	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SOX17 KCP IRF7 SLFN5 ARAP3 EGFL7	3.85e-06	165	112	6	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX17 CYTL1 EGFL7 LTBP4 NOTCH1 NOTCH4	3.99e-06	166	112	6	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX17 CYTL1 EGFL7 LTBP4 NOTCH1 NOTCH4	3.99e-06	166	112	6	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	EPHB4 SOX17 HOXA3 ARAP3 EGFL7 NOTCH4	4.27e-06	168	112	6	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB4 DLGAP2 CYTL1 ARAP3 EGFL7 NALF2	5.06e-06	173	112	6	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	facs-Heart-RA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 ARAP3 EGFL7 NOTCH1	6.35e-06	180	112	6	174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 KCP IER5 ARAP3 EGFL7 LTBP4	6.35e-06	180	112	6	2405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 KCP IER5 ARAP3 EGFL7 LTBP4	6.35e-06	180	112	6	9c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 KCP IER5 ARAP3 EGFL7 LTBP4	6.35e-06	180	112	6	499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COQ10B FAM162B SCAF1 AJUBA NOTCH3 ZNF687	6.56e-06	181	112	6	274c0b768925cd5804483303f8c5ebd17a534c41
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX17 CYTL1 EGFL7 LTBP4 NOTCH1 NOTCH4	6.56e-06	181	112	6	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCN2 RAX FAM162B BHLHE22 AJUBA NOTCH3	6.77e-06	182	112	6	9edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCN2 RAX FAM162B BHLHE22 AJUBA NOTCH3	6.77e-06	182	112	6	aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	6.77e-06	182	112	6	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX17 CYTL1 EGFL7 LTBP4 NOTCH1 NOTCH4	6.98e-06	183	112	6	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4	6.98e-06	183	112	6	c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4	6.98e-06	183	112	6	c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 LTBP4	6.98e-06	183	112	6	92eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSEN2 CYTL1 HOXA3 EGFL7 LTBP4 NOTCH4	7.20e-06	184	112	6	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	droplet-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL9A1 COL19A1 KCP KCNA3 HMCN2 CHRD	7.20e-06	184	112	6	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 HCN2 FAM162B BHLHE22 AJUBA NOTCH3	7.20e-06	184	112	6	4cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCell	droplet-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	1d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCell	droplet-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	76caad53d55fff5acca27bf190a6de7b27437d9f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	1fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	7.20e-06	184	112	6	2467207aaea307873ab286f89cfc7668a227a694
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 HCN2 FAM162B BHLHE22 AJUBA NOTCH3	7.20e-06	184	112	6	39bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 LTBP4 NOTCH4	7.43e-06	185	112	6	62cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ZFPM1 ARAP3 EGFL7 LTBP4	7.43e-06	185	112	6	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 CYTL1 ARAP3 EGFL7 NOTCH1 NOTCH4	7.43e-06	185	112	6	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 IRF7 SLFN5 EGFL7 NOTCH1	7.90e-06	187	112	6	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 IRF7 SLFN5 EGFL7 NOTCH1	7.90e-06	187	112	6	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX17 ZFPM1 EGFL7 LTBP4 NOTCH1 NOTCH4	8.14e-06	188	112	6	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 BHLHE22 LTBP4 NOTCH3 NOTCH4 HR	8.14e-06	188	112	6	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH4	8.14e-06	188	112	6	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.14e-06	188	112	6	20072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCell	facs-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.14e-06	188	112	6	dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 CSF2RB EGFL7 NOTCH4	8.14e-06	188	112	6	05de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	WDR81 LAMA2 HMCN2 BHLHE22 ADAM33 NOTCH4	8.14e-06	188	112	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH4	8.14e-06	188	112	6	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.14e-06	188	112	6	6ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH4	8.14e-06	188	112	6	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	EPHB4 SOX17 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH1	8.39e-06	189	112	6	ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 SLFN5 EGFL7 NOTCH1	8.39e-06	189	112	6	d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 TOX SOX17 CYTL1 EGFL7 LTBP4	8.39e-06	189	112	6	d17e8467699c7ca7694a313c26111f085df5204e
ToppCell	facs-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 IRF7 SLFN5 ARAP3 EGFL7	8.39e-06	189	112	6	88c0dda28f072368c0df30fc82ee3af9c7670f6c
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX17 CYTL1 EGFL7 LTBP4 NOTCH1 NOTCH4	8.39e-06	189	112	6	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	droplet-Kidney-nan-18m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 IRF7 SLFN5 ARAP3 EGFL7	8.39e-06	189	112	6	91261fe86f0d54b9697f85bb4d3ebdc8975b1bfa
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 SLFN5 EGFL7 NOTCH1	8.39e-06	189	112	6	476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH1	8.39e-06	189	112	6	e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL9A1 SOX17 ARAP3 EGFL7 LTBP4 NOTCH4	8.39e-06	189	112	6	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 SOX17 CYTL1 SLFN5 EGFL7 NOTCH1	8.39e-06	189	112	6	3fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCell	facs-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCell	facs-Trachea-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 SOX17 SLFN5 ARAP3 EGFL7 NOTCH1	8.39e-06	189	112	6	f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCell	facs-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	5559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 IRF7 SLFN5 EGFL7 LTBP4 NOTCH1	8.39e-06	189	112	6	92319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX17 SLFN5 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	28b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	EPHB4 SOX17 ARAP3 EGFL7 NOTCH1 NOTCH4	8.39e-06	189	112	6	d4a25d59d88325d3b20f4287e9b1160c82961a96
Disease	Carcinoma, Pancreatic Ductal	STK11 NOTCH1 NOTCH3 NOTCH4	1.47e-06	24	104	4	C0887833
Disease	hemangiopericytoma (is_marker_for)	EPHB4 NOTCH1 NOTCH4	3.52e-06	9	104	3	DOID:264 (is_marker_for)
Disease	Squamous cell carcinoma	STK11 LGR6 NOTCH1 NOTCH3 NOTCH4	7.97e-05	124	104	5	C0007137
Disease	brain cancer (implicated_via_orthology)	L3MBTL1 NOTCH1 NOTCH3	1.04e-04	26	104	3	DOID:1319 (implicated_via_orthology)
Disease	cytotoxicity measurement, response to clozapine	DLGAP2 TOX PLPPR2	1.45e-04	29	104	3	EFO_0006952, GO_0097338
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH1 NOTCH3	2.55e-04	7	104	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH1 NOTCH3	2.55e-04	7	104	2	DOID:3620 (implicated_via_orthology)
Disease	endometrial cancer (is_marker_for)	STK11 NOTCH1 NOTCH4	2.56e-04	35	104	3	DOID:1380 (is_marker_for)
Disease	cancer (implicated_via_orthology)	RBBP6 NKX2-8 PIP4K2B NOTCH1 NOTCH3 NOTCH4	3.83e-04	268	104	6	DOID:162 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	EPHB4 COL19A1 LAMA2 CRX HOXA3 ZNF668 ARAP3 ADAM33 LGR6 NOTCH1 NOTCH3 NOTCH4	4.05e-04	1074	104	12	C0006142
Disease	Colorectal Carcinoma	EFS SOX17 LGR5 STK11 ARAP3 LGR6 ZNHIT1 PLPPR2 HR	8.55e-04	702	104	9	C0009402
Disease	obesity (implicated_via_orthology)	SEC16A NOTCH1 PLXNB3 NOTCH3 NOTCH4	1.00e-03	215	104	5	DOID:9970 (implicated_via_orthology)
Disease	Malignant neoplasm of skin	NOTCH1 NOTCH3 NOTCH4	1.20e-03	59	104	3	C0007114
Disease	Skin Neoplasms	NOTCH1 NOTCH3 NOTCH4	1.20e-03	59	104	3	C0037286
Disease	Myopia	COL9A1 LAMA2	1.25e-03	15	104	2	C0027092
Disease	endoplasmic reticulum resident protein 29 measurement	EGFL7 NOTCH4	1.43e-03	16	104	2	EFO_0020346
Disease	Dementia	PSEN2 NOTCH3	1.62e-03	17	104	2	C0497327
Disease	clostridium difficile infection	DLGAP2 PSEN2 CLLU1-AS1 FRMPD3	1.71e-03	144	104	4	EFO_0009130
Disease	schizophrenia, inflammatory bowel disease	TOX BCL2L12	1.81e-03	18	104	2	EFO_0003767, MONDO_0005090
Disease	DiGeorge syndrome (implicated_via_orthology)	HOXA3 CHRD	2.02e-03	19	104	2	DOID:11198 (implicated_via_orthology)
Disease	eosinophil count	PSEN2 LSG1 KCP IER5 ZFPM1 NCOR2 CSF2RB SEC16A TMEM131 AJUBA LTBP4 NOTCH1 NOTCH4	2.21e-03	1488	104	13	EFO_0004842
Disease	axial length measurement	LAMA2 ZNRF3 RSPO1	2.58e-03	77	104	3	EFO_0005318
Disease	Glioblastoma	LTBP4 NOTCH1 NOTCH3	2.77e-03	79	104	3	C0017636
Disease	spermatogenic failure (is_implicated_in)	FKBP6 MOV10L1	2.97e-03	23	104	2	DOID:0111910 (is_implicated_in)
Disease	Giant Cell Glioblastoma	LTBP4 NOTCH1 NOTCH3	3.30e-03	84	104	3	C0334588

Protein segments in the cluster

Peptide	Gene	Start	Entry
PAFSPGLALPPGCIY	nan	66	Q75L30
GLRSLFEGPPCPYPG	C6orf136	106	Q5SQH8
SPGLAPARPRYACCP	EGFL7	76	Q9UHF1
LPPPPYSCDPSGSDL	ALG13	961	Q9NP73
SDPYGQPPLPGFDSC	ALG13	1071	Q9NP73
SCPGLLPSDPSPGVY	ARAP3	656	Q8WWN8
CAPFRVGPAPGPYVA	ALX3	6	O95076
PCLFGPPLAGAPAGY	AJUBA	181	Q96IF1
RFSPGLPGYPRTCTL	COQ10B	166	Q9H8M1
GYPFSAGLPPAASCP	BHLHE22	346	Q8NFJ8
VLCGSARPKPYDPPG	ATF4	251	P18848
SLPIRPCYGLEPGPA	BCL2L12	156	Q9HB09
PPDVYLLDGSPCARG	ADAM33	496	Q9BZ11
RPPYLLSPADSCPGG	DLGAP2	116	Q9P1A6
RLCPEPPSAPSEYAG	CCDC142	536	Q17RM4
PPLPYAGCRRASGFP	ZFYVE19	11	Q96K21
PSLASPAVPAPGYCS	HJURP	181	Q8NCD3
RFFCPPPCVYLSGPG	RBPJL	86	Q9UBG7
VGGLPPYATFPRQCP	OTUD7B	721	Q6GQQ9
TEPGKYPCGEFSPRP	FAM47C	176	Q5HY64
GTPRSPDYILPCSPG	ABCC10	51	Q5T3U5
LPAPLYSFPGASCPV	NCOR2	2156	Q9Y618
YLASAPPPLCPSGRT	PLD3	291	Q8IV08
GTPTLSPPLCSPNGY	NOTCH1	2131	P46531
CRPLPYILFGPPGTG	MOV10L1	761	Q9BXT6
SGKLLYCHPPPGRDP	LSG1	541	Q9H089
DAVPAPGPSPSLYCR	EPHB4	226	P54760
GLPPASYPASLPSCA	HOXA3	306	O43365
YGASPLCLPYAPPEG	LGR6	711	Q9HBX8
SPALSGLPRPASPYG	MYO15A	681	Q9UKN7
RSSPGLGYCSPLAPP	MYO15A	781	Q9UKN7
DTPCPATYRQGPSPG	HMCN2	4931	Q8NDA2
NLGYQLGPPATPRCP	HR	301	O43593
ADGQPACRYGPLCPP	PLXNB3	811	Q9ULL4
PSSASPGGCPPLSYR	L3MBTL1	591	Q9Y468
PGGCPPLSYRSLPHT	L3MBTL1	596	Q9Y468
CPYCPPNGPVRGDLL	ZFPM1	856	Q8IX07
PAGYTGPLCENPAVP	NOTCH3	186	Q9UM47
CYPTLRPTAGRTPAP	MYRFL	71	Q96LU7
GGCDRYEPLPPSLPA	KCNA3	81	P22001
PYGSLPVPCDPVTGF	LAMA2	1531	P24043
EPSAPPGTCGPRYSN	NALF2	106	O75949
GHPSCTFLYGPPDPA	IRF7	306	Q92985
CPLPGYPAFGPGSAL	NKX2-8	206	O15522
GAPAARPTPPTCYSR	CYTL1	16	Q9NRR1
DVVYGALPPPGCDPS	MEF2B	141	Q02080
PLGPPPPSYTCFRCG	RBBP6	151	Q7Z6E9
YTALGCLPPSPDRPG	PLPPR2	166	Q96GM1
PGCPAPCPLGRFYQL	ACP4	351	Q9BZG2
YAYGTLGCPPLIPPN	FKBP6	116	O75344
SYSCSAPEAPPPLGA	FAM189B	401	P81408
PFLGPSPPDRCAGFL	FBRS	346	Q9HAH7
PPPGSLEYLCLPAGG	CSF2RB	621	P32927
DYCFLPGLGPGPLSL	CSF2RB	821	P32927
GSPRVPPLSLGYGVC	KLRG2	76	A4D1S0
PLVCLGDYRTPDPGG	C5orf67	36	F2Z3F1
PPGPSGRCNPEDCLY	COL19A1	1116	Q14993
PGTEYLQPPAPGRCS	FRMPD3	1296	Q5JV73
IPRSASYPCAAPRPG	ATG9A	756	Q7Z3C6
CLGPPTTPGPYRSIY	MPG	61	P29372
PPTALRVPSSGPYDC	EFS	151	O43281
PSSPDGALTRPPYCL	BLOC1S6	6	Q9UL45
PPYCLEAGEPTPGLS	BLOC1S6	16	Q9UL45
CPYLTVPGPPGAESG	FRMD6-AS1	31	P0C7T7
LCGASPLLVPGDPYS	MBLAC1	6	A4D2B0
SCAPGYRAPSGRPGP	LTBP4	861	Q8N2S1
APGYRPGPRGASCLD	LTBP4	906	Q8N2S1
CPNACPPGRSGYPGL	COL9A1	411	P20849
PPPYSLTDSCPTLDG	BEAN1	166	Q3B7T3
DTLPPYEAVCGAGPP	BEAN1	211	Q3B7T3
YEAVCGAGPPSGLLP	BEAN1	216	Q3B7T3
SPRAPRTSPYGGLPA	HCN2	786	Q9UL51
VCPDPLGISDSYSPP	CRX	131	O43186
PAPALPPRGLPCYSS	FAM162B	31	Q5T6X4
PPRGLPCYSSGGAPS	FAM162B	36	Q5T6X4
YGASPLCLPLPFGEP	LGR5	706	O75473
YPRAGSKPPSCPAPG	OAS3	376	Q9Y6K5
PCPGLYLAGPAGTPA	IER5	51	Q5VY09
YELREPCGPLGGPAP	SKOR1	756	P84550
CQSLGAPPLDGYPLP	SOX17	206	Q9H6I2
GTYCLAPPPPGIDVT	SFSWAP	376	Q12872
PSGDPCYSPLGLAGL	SSPOP	2061	A2VEC9
ECASLCPYPARPLPG	KCP	291	Q6ZWJ8
LLCSYGTPPDSPGNL	PIP4K2B	316	P78356
PSLGRSYSCPDLGPP	PRR14	326	Q9BWN1
LSYFRCDDPPSPSPG	SPATA31A7	46	Q8IWB4
LPSCPPGYFDARNPD	RSPO1	76	Q2MKA7
PSALCQTPGYGFLPP	SAMD11	321	Q96NU1
SYAIPGDCGPPLSDL	STK11	271	Q15831
PKPGFPPRCACLSGY	NOTCH4	1106	Q99466
YCPKEPGEARPSPGL	RAX	101	Q9Y2V3
GCPDIPSLGLGPYVS	SLURP2	71	P0DP57
LPGLPRSRDPGEGCY	CHRD	771	Q9H2X0
CTSYGPALGAPLPGR	CLLU1-AS1	31	Q5K130
GCAAPGPASYRRPPS	VGLL4	186	Q14135
LSYFRCDDPPSPSPG	SPATA31A3	46	Q5VYP0
QASGPSTPGYRCPEP	ZXDC	166	Q2QGD7
GSAAKPRPYACPLCP	ZNF668	76	Q96K58
TCPYLPPFPARGSGI	MRPL38	251	Q96DV4
LSYFRCDDPPSPSPG	SPATA31A1	46	Q5TZJ5
DDFCSSPGLGRPPAP	SEC16A	401	O15027
LSYFRCDDPPSPSPG	SPATA31A5	46	Q5VU36
PPPLCGAIPASGDYV	SGF29	141	Q96ES7
PSSYLLPGSLPLGGC	SCAF1	1161	Q9H7N4
LYSAPGVDPSPPCRS	SPDYE16	11	A6NNV3
LYSAPGVDPSPPCRS	SPDYE1	11	Q8NFV5
SPPAAPCPFVARGSY	TMEM131	1606	Q92545
DRYVCSGVPGRPPGL	PSEN2	61	P49810
PSPLCPVPAGGGFYL	PPP1R3F	101	Q6ZSY5
PPPLGLCDYPSSRAM	TTLL12	566	Q14166
ALAYRPLGASLGCPP	TOP3A	861	Q13472
TADCPIFYPPGPLGG	ZNF862	236	O60290
TEEPPPGCYPGARDL	ZNRF3	811	Q9ULT6
PAEAGLALPPTGYRC	ZNF687	521	Q8N1G0
LYSAPGVDPSPPCRS	nan	11	A6NJR5
YADFLPPGACPAPAR	WTIP	156	A6NIX2
YLTACAGPPSRPQRP	ZNHIT1	101	O43257
GARSSCPGDYPSPPS	ZC3H12C	716	Q9C0D7
DLYPVPAPCFGPLGS	TMEM207	121	Q6UWW9
YCLPPRAPGSSPGSA	TMEM271	156	A0A286YF58
PDAPCLGPSPCLDPY	TOX	16	O94900
LSCSGLPPPSDQYPR	SLFN5	691	Q08AF3
YAREGPCPPRGSPAC	WDR81	201	Q562E7
PANLGYARGVDPPPC	TM7SF3	166	Q9NS93