Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PI4K2B NPR1 FLT3 NPR2 CDC42BPA SAMD8 POLR3H GRK5 GRK6 OAS3 ACVR1 NRP2 SBK1 PI4KA CSNK2B PANK4 IRAK3 PRIMPOL	7.65e-06	938	116	18	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	PI4K2B NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 NRP2 SBK1 PI4KA CSNK2B PANK4 IRAK3	6.35e-05	709	116	14	GO:0016773
GeneOntologyMolecularFunction	NACHT domain binding	TRIM16 TRIM16L	1.00e-04	3	116	2	GO:0032089
GeneOntologyMolecularFunction	natriuretic peptide receptor activity	NPR1 NPR2	1.00e-04	3	116	2	GO:0016941
GeneOntologyMolecularFunction	kinase activity	PI4K2B NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 NRP2 SBK1 PI4KA CSNK2B PANK4 IRAK3	1.40e-04	764	116	14	GO:0016301
GeneOntologyMolecularFunction	1-phosphatidylinositol 4-kinase activity	PI4K2B PI4KA	1.99e-04	4	116	2	GO:0004430
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK5 GRK6	1.99e-04	4	116	2	GO:0047696
GeneOntologyMolecularFunction	clathrin adaptor activity	AP1M2 ARRB1 AP1S2	2.71e-04	22	116	3	GO:0035615
GeneOntologyMolecularFunction	cargo adaptor activity	AP1M2 ARRB1 AP1S2	4.00e-04	25	116	3	GO:0140312
GeneOntologyMolecularFunction	vascular endothelial growth factor receptor activity	FLT3 NRP2	6.89e-04	7	116	2	GO:0005021
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK5 GRK6	6.89e-04	7	116	2	GO:0004703
GeneOntologyMolecularFunction	protein kinase activity	NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 NRP2 SBK1 CSNK2B IRAK3	7.47e-04	600	116	11	GO:0004672
Domain	-	GTF2IRD2B GTF2I GTF2IRD2	9.30e-07	4	116	3	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2I GTF2IRD2	9.30e-07	4	116	3	PS51139
Domain	GTF2I	GTF2IRD2B GTF2I GTF2IRD2	9.30e-07	4	116	3	PF02946
Domain	GTF2I	GTF2IRD2B GTF2I GTF2IRD2	9.30e-07	4	116	3	IPR004212
Domain	CUB	MFRP CSMD3 NRP2 BMP1 TLL2	1.30e-05	49	116	5	PF00431
Domain	CUB	MFRP CSMD3 NRP2 BMP1 TLL2	1.44e-05	50	116	5	SM00042
Domain	-	MFRP CSMD3 NRP2 BMP1 TLL2	1.74e-05	52	116	5	2.60.120.290
Domain	CUB	MFRP CSMD3 NRP2 BMP1 TLL2	1.92e-05	53	116	5	PS01180
Domain	CUB_dom	MFRP CSMD3 NRP2 BMP1 TLL2	2.74e-05	57	116	5	IPR000859
Domain	Cytoplasmic_FMR1-int	CYFIP2 CYFIP1	3.82e-05	2	116	2	IPR008081
Domain	FragX_IP	CYFIP2 CYFIP1	3.82e-05	2	116	2	PF05994
Domain	DUF3498	DAB2IP RASAL2	1.14e-04	3	116	2	IPR021887
Domain	BMP_1/tolloid-like	BMP1 TLL2	1.14e-04	3	116	2	IPR015446
Domain	ANF_RECEPTORS	NPR1 NPR2	1.14e-04	3	116	2	PS00458
Domain	DUF3498	DAB2IP RASAL2	1.14e-04	3	116	2	PF12004
Domain	ANPR/GUC	NPR1 NPR2	1.14e-04	3	116	2	IPR001170
Domain	NKAIN	NKAIN2 NKAIN1	2.28e-04	4	116	2	PF05640
Domain	Na/K-Atpase_Interacting	NKAIN2 NKAIN1	2.28e-04	4	116	2	IPR008516
Domain	DUF1394	CYFIP2 CYFIP1	2.28e-04	4	116	2	IPR009828
Domain	DUF1394	CYFIP2 CYFIP1	2.28e-04	4	116	2	PF07159
Domain	ConA-like_dom	CLGN ADGRV1 HNRNPU NRP2 TRIM16 TRIM16L TRIM36	4.38e-04	219	116	7	IPR013320
Domain	Peptidase_M12A	BMP1 TLL2	5.64e-04	6	116	2	IPR001506
Domain	Astacin	BMP1 TLL2	5.64e-04	6	116	2	PF01400
Domain	GPCR_kinase	GRK5 GRK6	7.87e-04	7	116	2	IPR000239
Domain	Calx_beta	ADGRV1 FREM3	1.04e-03	8	116	2	SM00237
Domain	Death	MYD88 IRAK3 DTHD1	1.11e-03	33	116	3	PF00531
Domain	Calx_beta	ADGRV1 FREM3	1.34e-03	9	116	2	IPR003644
Domain	Calx-beta	ADGRV1 FREM3	1.34e-03	9	116	2	PF03160
Domain	Death_domain	MYD88 IRAK3 DTHD1	1.68e-03	38	116	3	IPR000488
Domain	DEATH_DOMAIN	MYD88 IRAK3 DTHD1	1.68e-03	38	116	3	PS50017
Domain	Kinase-like_dom	NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 SBK1 PI4KA IRAK3	2.03e-03	542	116	10	IPR011009
Domain	-	NLRP11 MYD88 IRAK3 DTHD1	2.70e-03	93	116	4	1.10.533.10
Domain	SPRY	HNRNPU TRIM16 TRIM16L TRIM36	2.80e-03	94	116	4	PF00622
Domain	SPRY_dom	HNRNPU TRIM16 TRIM16L TRIM36	2.80e-03	94	116	4	IPR003877
Domain	B30.2/SPRY	HNRNPU TRIM16 TRIM16L TRIM36	2.91e-03	95	116	4	IPR001870
Domain	B302_SPRY	HNRNPU TRIM16 TRIM16L TRIM36	2.91e-03	95	116	4	PS50188
Domain	RasGAP	DAB2IP RASAL2	3.31e-03	14	116	2	SM00323
Domain	RasGAP_CS	DAB2IP RASAL2	3.31e-03	14	116	2	IPR023152
Domain	DEATH-like_dom	NLRP11 MYD88 IRAK3 DTHD1	3.38e-03	99	116	4	IPR011029
Domain	Prot_kinase_dom	NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 SBK1 IRAK3	3.45e-03	489	116	9	IPR000719
Domain	PROTEIN_KINASE_DOM	NPR1 FLT3 NPR2 CDC42BPA GRK5 GRK6 ACVR1 SBK1 IRAK3	3.64e-03	493	116	9	PS50011
Domain	RasGAP	DAB2IP RASAL2	3.81e-03	15	116	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	DAB2IP RASAL2	3.81e-03	15	116	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	DAB2IP RASAL2	3.81e-03	15	116	2	PS50018
Domain	AP_mu_sigma_su	AP1M2 AP1S2	4.34e-03	16	116	2	IPR022775
Domain	Clat_adaptor_s	AP1M2 AP1S2	4.34e-03	16	116	2	PF01217
Domain	-	DAB2IP RASAL2	4.34e-03	16	116	2	1.10.506.10
Domain	A/G_cyclase_CS	NPR1 NPR2	4.89e-03	17	116	2	IPR018297
Domain	AGC-kinase_C	CDC42BPA GRK5 GRK6	5.09e-03	56	116	3	IPR000961
Domain	AGC_KINASE_CTER	CDC42BPA GRK5 GRK6	5.09e-03	56	116	3	PS51285
Domain	S_TK_X	CDC42BPA GRK5 GRK6	5.09e-03	56	116	3	SM00133
Domain	PI3_PI4_kinase	PI4K2B PI4KA	5.48e-03	18	116	2	PF00454
Domain	PI3_4_KINASE_1	PI4K2B PI4KA	5.48e-03	18	116	2	PS00915
Domain	PI3_4_KINASE_2	PI4K2B PI4KA	5.48e-03	18	116	2	PS00916
Domain	-	NPR1 NPR2	5.48e-03	18	116	2	3.30.70.1230
Domain	PI3/4_kinase_cat_dom	PI4K2B PI4KA	5.48e-03	18	116	2	IPR000403
Domain	RasGAP_dom	DAB2IP RASAL2	5.48e-03	18	116	2	IPR001936
Domain	PI3_4_KINASE_3	PI4K2B PI4KA	5.48e-03	18	116	2	PS50290
Domain	Nucleotide_cyclase	NPR1 NPR2	5.48e-03	18	116	2	IPR029787
Domain	Guanylate_cyc	NPR1 NPR2	6.10e-03	19	116	2	PF00211
Domain	GUANYLATE_CYCLASE_2	NPR1 NPR2	6.10e-03	19	116	2	PS50125
Domain	A/G_cyclase	NPR1 NPR2	6.10e-03	19	116	2	IPR001054
Domain	GUANYLATE_CYCLASE_1	NPR1 NPR2	6.10e-03	19	116	2	PS00452
Domain	CYCc	NPR1 NPR2	6.10e-03	19	116	2	SM00044
Pubmed	HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis induces tyrosinemia and neurological damage.	DSP ARFGEF2 GTF2I HPD	8.72e-09	8	118	4	31537781
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2I GTF2IRD2	1.52e-07	4	118	3	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2I GTF2IRD2	1.52e-07	4	118	3	22899722
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2I GTF2IRD2	1.52e-07	4	118	3	17823943
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2I GTF2IRD2	1.52e-07	4	118	3	21328569
Pubmed	beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress.	GRK5 GRK6 ARRB1	7.56e-07	6	118	3	20530803
Pubmed	Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.	GRK5 GRK6 ARRB1	7.56e-07	6	118	3	17060617
Pubmed	β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling.	GRK5 GRK6 ARRB1	7.56e-07	6	118	3	29627294
Pubmed	Characterization of a novel cardiac isoform of the cell cycle-related kinase that is regulated during heart failure.	CSNK2B PANK4 GTF2IRD2	7.56e-07	6	118	3	18508765
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TTF2 CDC42BPA ZFYVE16 DSP HSPA4L EXOC3 HM13 DNAJC7 HNRNPU CYFIP1 CRYBG3 DHX29 RASAL2	9.07e-07	708	118	13	39231216
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RARS1 DSP HSPA4L MTHFD1L DDX56 DNAJC7 CYFIP2 HNRNPU GBA3 CYFIP1 GTF2I BAZ1A PI4KA CSNK2B UTP20 DHX29 CLUH RASAL2	1.53e-06	1425	118	18	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DSP HSPA4L GRK5 GRK6 CNPY2 PLA2G4D DNAJC7 CYFIP2 HNRNPU TRIM16 GTF2IRD2B ARRB1 SUGCT BAZ1A GTF2IRD2 IRAK3 DTHD1 TASOR	1.81e-06	1442	118	18	35575683
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TTF2 RARS1 DSP MTHFD1L EXOC3 OAS3 DDX56 ECH1 HNRNPU CYFIP1 GTF2I BAZ1A PI4KA CSNK2B UTP20 DHX29 RASAL2	3.31e-06	1353	118	17	29467282
Pubmed	GGAs: roles of the different domains and comparison with AP-1 and clathrin.	AP1M2 ARRB1 AP1S2	4.49e-06	10	118	3	11694590
Pubmed	The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.	NPR1 NPR2	1.14e-05	2	118	2	30696704
Pubmed	Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.	CYFIP2 CYFIP1	1.14e-05	2	118	2	38128786
Pubmed	Chimeric natriuretic peptide ACNP stimulates both natriuretic peptide receptors, the NPRA and NPRB.	NPR1 NPR2	1.14e-05	2	118	2	23186809
Pubmed	Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers.	DAB2IP RASAL2	1.14e-05	2	118	2	27974415
Pubmed	Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.	TRIM16 TRIM16L	1.14e-05	2	118	2	23341783
Pubmed	The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation.	TRIM16 TRIM16L	1.14e-05	2	118	2	11919186
Pubmed	Pendred Syndrome, or Not Pendred Syndrome? That Is the Question.	SLC26A4 MYO5C	1.14e-05	2	118	2	34680964
Pubmed	Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.	F3 C5	1.14e-05	2	118	2	29437288
Pubmed	ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.	NPR1 NPR2	1.14e-05	2	118	2	21828054
Pubmed	Porcine natriuretic peptide type B (pNPPB) maintains mouse oocyte meiotic arrest via natriuretic peptide receptor 2 (NPR2) in cumulus cells.	NPR1 NPR2	1.14e-05	2	118	2	24615855
Pubmed	Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.	TRIM16 TRIM16L	1.14e-05	2	118	2	31342168
Pubmed	Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB.	NPR1 NPR2	1.14e-05	2	118	2	24699414
Pubmed	Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte.	NPR1 NPR2	1.14e-05	2	118	2	22133375
Pubmed	The E3 Ligase TRIM16 Is a Key Suppressor of Pathological Cardiac Hypertrophy.	TRIM16 TRIM16L	1.14e-05	2	118	2	35437018
Pubmed	Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.	CYFIP2 CYFIP1	1.14e-05	2	118	2	29752658
Pubmed	TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.	TRIM16 TRIM16L	1.14e-05	2	118	2	32251645
Pubmed	Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.	NPR1 NPR2	1.14e-05	2	118	2	22949736
Pubmed	Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.	NPR1 NPR2	1.14e-05	2	118	2	28765884
Pubmed	ATP-independent activation of natriuretic peptide receptors.	NPR1 NPR2	1.14e-05	2	118	2	15911610
Pubmed	Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.	GRK5 GRK6	1.14e-05	2	118	2	17786238
Pubmed	Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.	NPR1 NPR2	1.14e-05	2	118	2	17848634
Pubmed	C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.	CYFIP2 CYFIP1	1.14e-05	2	118	2	24357318
Pubmed	Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.	GRK5 GRK6	1.14e-05	2	118	2	20038610
Pubmed	CircIRAK3 exerts negative feedback regulation on inflammation by binding to HNRNP U and destabilizing proinflammatory cytokine mRNA in osteoarthritis and chondrogenesis.	HNRNPU IRAK3	1.14e-05	2	118	2	38016613
Pubmed	MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.	MYD88 IRAK3	1.14e-05	2	118	2	34735922
Pubmed	Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.	NPR1 NPR2	1.14e-05	2	118	2	20977274
Pubmed	Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQ.	ADGRV1 PTPRQ	1.14e-05	2	118	2	22357859
Pubmed	Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1.	TRIM16 TRIM16L	1.14e-05	2	118	2	34146477
Pubmed	Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.	CYFIP2 CYFIP1	1.14e-05	2	118	2	34327661
Pubmed	Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.	CYFIP2 CYFIP1	1.14e-05	2	118	2	35567753
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.14e-05	2	118	2	15388857
Pubmed	Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.	CYFIP2 CYFIP1	1.14e-05	2	118	2	31324746
Pubmed	The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B.	NPR1 NPR2	1.14e-05	2	118	2	21366551
Pubmed	Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.	ARRB1 PI4KA CSNK2B	1.68e-05	15	118	3	29999490
Pubmed	Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.	DAB2IP NKAIN2 MFSD2A	2.99e-05	18	118	3	23534349
Pubmed	Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.	GRK5 GRK6	3.42e-05	3	118	2	7789183
Pubmed	G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.	GRK5 GRK6	3.42e-05	3	118	2	19801552
Pubmed	Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor.	PI4K2B PI4KA	3.42e-05	3	118	2	11907035
Pubmed	Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.	BMP1 TLL2	3.42e-05	3	118	2	18824173
Pubmed	A sensitive method for determining the phosphorylation status of natriuretic peptide receptors: cGK-Ialpha does not regulate NPR-A.	NPR1 NPR2	3.42e-05	3	118	2	16430226
Pubmed	Skeletal muscle derived Musclin protects the heart during pathological overload.	NPR1 NPR2	3.42e-05	3	118	2	35013221
Pubmed	RNA Binding Proteins that Mediate LPS-induced Alternative Splicing of the MyD88 Innate Immune Regulator.	MYD88 HNRNPU	3.42e-05	3	118	2	38369277
Pubmed	CircPI4KA Overexpression Enhances Carcinogenesis and Glycolysis Metabolism in Papillary Thyroid Carcinoma by Causing the miR-1287-5p-Mediated NRP2 Expression Elevation.	NRP2 PI4KA	3.42e-05	3	118	2	37813099
Pubmed	Genetic analysis of the role of proteolysis in the activation of latent myostatin.	BMP1 TLL2	3.42e-05	3	118	2	18286185
Pubmed	Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).	GRK5 GRK6	3.42e-05	3	118	2	18662895
Pubmed	Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.	GRK5 GRK6	3.42e-05	3	118	2	12032308
Pubmed	Regulation of natriuretic peptides postprandially in vivo and of their receptors in adipocytes by fatty acids in vitro.	NPR1 NPR2	3.42e-05	3	118	2	29409758
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	3.42e-05	3	118	2	15100712
Pubmed	Chromosomal distribution of three members of the human natriuretic peptide receptor/guanylyl cyclase gene family.	NPR1 NPR2	3.42e-05	3	118	2	1979052
Pubmed	Expression of G-protein-coupled receptor kinases in pregnant term and non-pregnant human myometrium.	GRK5 GRK6	3.42e-05	3	118	2	10467231
Pubmed	Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: regulation and therapeutic implications.	NPR1 NPR2	3.42e-05	3	118	2	25117468
Pubmed	IFT20 Confers Paclitaxel Resistance by Triggering β-arrestin-1 to Modulate ASK1 Signaling in Breast Cancer.	IFT20 ARRB1	3.42e-05	3	118	2	36573960
Pubmed	Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue.	NPR1 NPR2	3.42e-05	3	118	2	36618828
Pubmed	TRIM16 exerts protective function on myocardial ischemia/reperfusion injury through reducing pyroptosis and inflammation via NLRP3 signaling.	TRIM16 TRIM16L	3.42e-05	3	118	2	36208489
Pubmed	Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.	NPR1 NPR2	3.42e-05	3	118	2	15459247
Pubmed	CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading.	NPR1 CCM2	3.42e-05	3	118	2	28432261
Pubmed	MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway.	MYD88 C5	3.42e-05	3	118	2	21859896
Pubmed	Defining the membrane proteome of NK cells.	PI4K2B RARS1 MTHFD1L GRK6 ARFGEF2 DDX56 HM13 DNAJC7 ECH1 CYFIP2 HNRNPU GTF2I OSBPL3 PI4KA	4.36e-05	1168	118	14	19946888
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DGCR2 CDC42BPA EAPP HSPA4L MTHFD1L EXOC3 CNPY2 HM13 DNAJC7 ECH1 PI4KA PANK4 CRYBG3 DHX29 CLUH RASAL2	4.39e-05	1487	118	16	33957083
Pubmed	Physiological and pathophysiological characteristics of ataxin-3 isoforms.	RARS1 DSP HSPA4L DNAJC7 HNRNPU CYFIP1 GTF2I	5.12e-05	281	118	7	30455355
Pubmed	G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.	GRK5 GRK6	6.82e-05	4	118	2	29969579
Pubmed	MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva.	MYD88 ACVR1	6.82e-05	4	118	2	34206078
Pubmed	GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2.	NPR2 NRP2	6.82e-05	4	118	2	23892628
Pubmed	Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.	CYFIP2 CYFIP1	6.82e-05	4	118	2	27605705
Pubmed	Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2.	CSNK2B PLEKHO1	6.82e-05	4	118	2	10799509
Pubmed	Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.	CYFIP2 CYFIP1	6.82e-05	4	118	2	20228810
Pubmed	Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.	GRK5 ARRB1	6.82e-05	4	118	2	19661922
Pubmed	Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated beta-cells.	PI4K2B PI4KA	6.82e-05	4	118	2	20375060
Pubmed	Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.	GRK5 GRK6	6.82e-05	4	118	2	21784156
Pubmed	Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.	GRK5 GRK6	6.82e-05	4	118	2	11504827
Pubmed	Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.	CYFIP2 CYFIP1	6.82e-05	4	118	2	15294869
Pubmed	Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain.	XIRP2 PTPRQ	6.82e-05	4	118	2	37294664
Pubmed	Migrating Myeloid Cells Sense Temporal Dynamics of Chemoattractant Concentrations.	GRK6 ARRB1	6.82e-05	4	118	2	29166587
Pubmed	A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation.	NPR1 NPR2	6.82e-05	4	118	2	19458086
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CDC42BPA DSP ARFGEF2 MYO5C PI4KA UTP20	6.84e-05	202	118	6	33005030
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZFYVE16 DSP INPP4A MECOM INPP5F GTF2I CRYBG3 TASOR	9.42e-05	418	118	8	34709266
Pubmed	Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.	MECOM NRP2 BMP1	1.05e-04	27	118	3	24586749
Pubmed	Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development.	F3 C5	1.13e-04	5	118	2	28223279
Pubmed	Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.	GRK5 GRK6	1.13e-04	5	118	2	12507501
Pubmed	Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.	INPP4A INPP5F	1.13e-04	5	118	2	25869668
Pubmed	ENaC is regulated by natriuretic peptide receptor-dependent cGMP signaling.	NPR1 NPR2	1.13e-04	5	118	2	23324181
Pubmed	c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.	GRK5 GRK6	1.13e-04	5	118	2	27232975
Pubmed	Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine.	MYD88 IRAK3	1.13e-04	5	118	2	21182089
Pubmed	Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates.	MYD88 IRAK3	1.13e-04	5	118	2	21690387
Pubmed	IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase.	MYD88 IRAK3	1.13e-04	5	118	2	11960013
Pubmed	Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90.	PI4K2B PI4KA	1.13e-04	5	118	2	21330372
Interaction	HPD interactions	DSP ARFGEF2 GTF2I HPD	2.42e-06	17	117	4	int:HPD
GeneFamily	Na+/K+ transporting ATPase interacting	NKAIN2 NKAIN1	9.86e-05	4	74	2	659
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP1 TLL2	2.45e-04	6	74	2	894
GeneFamily	Guanylate cyclase receptors	NPR1 NPR2	3.42e-04	7	74	2	343
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	DAB2IP RASAL2	7.28e-04	10	74	2	830
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN	DSP USP43 ADGRV1 HNRNPU AP1S2 IRAK3 CRYBG3 TRIM36	3.35e-06	200	117	8	M4334
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 F3 MYO5C RAD51AP2 BMP1 MFSD2A C5	5.10e-07	179	118	7	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP1M2 F3 CYFIP2 MYO5C BMP1 MFSD2A C5	5.29e-07	180	118	7	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ADGRV1 CSMD3 NKAIN2 DNAH1 XIRP2 PTPRQ	6.14e-07	184	118	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ADGRV1 CSMD3 NKAIN2 DNAH1 XIRP2 PTPRQ	6.14e-07	184	118	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ADGRV1 CSMD3 NKAIN2 DNAH1 XIRP2 PTPRQ	6.14e-07	184	118	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 F3 CYFIP2 MYO5C BMP1 MFSD2A C5	6.60e-07	186	118	7	e83718fabb057100835d3357df407f283d23fe16
ToppCell	LPS-antiTNF-Epithelial_alveolar\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP AP1M2 F3 MYO5C BMP1 MFSD2A C5	6.84e-07	187	118	7	201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 F3 CYFIP2 MYO5C BMP1 MFSD2A C5	7.09e-07	188	118	7	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	IPF-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	ZFYVE16 HM13 NRP2 CYFIP1 PTPRE ZC3H12C PLEKHO1	1.04e-06	199	118	7	3c2b362d5e824e1a04830e70352f8818de984174
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DSP USP43 KLHL35 MECOM ADGRV1 PTPRQ	7.07e-06	174	118	6	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	F3 CYFIP2 MYO5C BMP1 MFSD2A C5	8.31e-06	179	118	6	7db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP1M2 F3 CYFIP2 BMP1 MFSD2A C5	9.13e-06	182	118	6	1e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP1M2 F3 CYFIP2 BMP1 MFSD2A C5	9.42e-06	183	118	6	5f2db95d44b7de68779de098892892af540fd431
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP1M2 F3 MYO5C BMP1 MFSD2A C5	9.42e-06	183	118	6	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP1M2 F3 CYFIP2 BMP1 MFSD2A C5	9.72e-06	184	118	6	157a3d00165bb4a8c52c3e63ae57d9cf57500be7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	F3 CYFIP2 MYO5C BMP1 MFSD2A C5	9.72e-06	184	118	6	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1-AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP USP43 AP1M2 F3 MYO5C C5	1.00e-05	185	118	6	68f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	F3 CYFIP2 MYO5C BMP1 MFSD2A C5	1.00e-05	185	118	6	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	LPS_only-Epithelial_alveolar\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP AP1M2 F3 MYO5C MFSD2A C5	1.03e-05	186	118	6	e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MTHFD1L MECOM HM13 F3 MYO5C MFSD2A	1.03e-05	186	118	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR1 EMILIN2 ADGRV1 TRIM16 BMP1 FBN1	1.07e-05	187	118	6	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP ADGRV1 F3 MYO5C OSBPL3 C5	1.07e-05	187	118	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP USP43 AP1M2 ADGRV1 MYO5C C5	1.13e-05	189	118	6	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MECOM ADGRV1 F3 MYO5C BMP1 MFSD2A	1.24e-05	192	118	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PI4K2B MTHFD1L POLR3H ZNF529 ZNF701 CLUH	1.24e-05	192	118	6	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSP USP43 AP1M2 ADGRV1 MYO5C MFSD2A	1.39e-05	196	118	6	7b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	FLT3 HLA-DOB ARFGEF2 CYFIP2 ZBED6 PI4KA	1.39e-05	196	118	6	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DSP ADGRV1 MYO5C OSBPL3 PTPRQ C5	1.43e-05	197	118	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT3 EMILIN2 ARRB1 PTPRE IRAK3 PLEKHO1	1.43e-05	197	118	6	57dafb3047745a44b2345b8036e159c3641d496e
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT3 EMILIN2 NRP2 PTPRE AP1S2 IRAK3	1.43e-05	197	118	6	555ea43eccc3eb22be230c27e13d8b3b64c2a61f
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DSP ADGRV1 CYFIP2 MYO5C BMP1 C5	1.47e-05	198	118	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EMILIN2 CYFIP1 PTPRE AP1S2 IRAK3 PLEKHO1	1.52e-05	199	118	6	4fc03377c017209111561789226621d258291481
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MECOM ADGRV1 MYO5C BMP1 MFSD2A PTPRE	1.52e-05	199	118	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FLT3 EMILIN2 CYFIP1 AP1S2 CRYBG3 PLEKHO1	1.52e-05	199	118	6	7dde5c02fcae64cd2d68f607500f2a46b97851fd
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FLT3 EMILIN2 CYFIP1 AP1S2 CRYBG3 PLEKHO1	1.52e-05	199	118	6	84879280851380e5bfe6bd48b6bbf57aedf6e003
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYD88 EMILIN2 ARFGEF2 PTPRE ZBED6 IRAK3	1.52e-05	199	118	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DSP ADGRV1 CYFIP2 MYO5C NRP2 C5	1.56e-05	200	118	6	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	Bronchial-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSP AP1M2 MECOM ADGRV1 F3 MYO5C	1.56e-05	200	118	6	d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AP1M2 MECOM F3 MYO5C BMP1 MFSD2A	1.56e-05	200	118	6	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	AP1M2 MECOM F3 MYO5C BMP1 MFSD2A	1.56e-05	200	118	6	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Biopsy_Control_(H.)-Epithelial\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DSP AP1M2 MECOM F3 MYO5C MFSD2A	1.56e-05	200	118	6	0afd93c4fdcc118bcfa77f3b59f6ff7d9293a7a4
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	AP1M2 MECOM F3 MYO5C BMP1 MFSD2A	1.56e-05	200	118	6	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	Sepsis-Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, condition lineage and cell class	FLT3 HLA-DOB IFT20 FBN1 PTPRE CRYBG3	1.56e-05	200	118	6	cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCell	Biopsy_Control_(H.)-Immune-Monocytes\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FLT3 EMILIN2 PTPRE AP1S2 IRAK3 PLEKHO1	1.56e-05	200	118	6	c58a5dc0a0d74a21ca15ee8b7a0197de32afa045
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6-Excitatory_NeuronSlc17a7-Slc17a6.Syt6-Nnat_(Deep_layer_pyramidal_cells--medial_cortex)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	OAS3 HPD PTPRQ DTHD1	3.41e-05	69	118	4	de297aa59c70f15c55cb9570439dc6d3fd6c182b
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	OAS3 HPD PTPRQ DTHD1	3.41e-05	69	118	4	31f4fb56dfa5e3ad7c83e0770960c3617e4f66a7
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMCO5A ADGRV1 TECTA CSMD3 PTPRQ	4.24e-05	145	118	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	PI4K2B INPP4A CYFIP2 BMP1 AP1S2	4.52e-05	147	118	5	87c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ADGRV1 TECTA PTPRQ DTHD1	6.76e-05	160	118	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ADGRV1 TECTA PTPRQ DTHD1	6.76e-05	160	118	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	severe_influenza-cDC\|World / disease group, cell group and cell class (v2)	FLT3 CLGN MTHFD1L MECOM MYO5C	6.96e-05	161	118	5	802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPR1 SLC26A4 S100A3 HPD TLL2	7.17e-05	162	118	5	2d28306c6125b31f11ea6d911a167b93a74907c5
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 CPT1B F3 NUDT12 MFSD2A	7.38e-05	163	118	5	ec8336b68c8369e27d507c04c827be07bb48a7f6
ToppCell	Influenza_Severe-cDC\|World / Disease group and Cell class	CLGN MTHFD1L MECOM DTD2 MYO5C	7.60e-05	164	118	5	c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT3 HLA-DOB MFSD2A PTPRE TRIM36	7.60e-05	164	118	5	43045879505774ac0d9b7f760557955564f06d00
ToppCell	Influenza_Severe-cDC\|Influenza_Severe / Disease group and Cell class	CLGN MTHFD1L MECOM DTD2 MYO5C	8.05e-05	166	118	5	b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EMILIN2 MECOM TECTA NKAIN2 IRAK3	8.05e-05	166	118	5	28a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EMILIN2 MECOM TECTA NKAIN2 IRAK3	8.05e-05	166	118	5	2a04915d534a83e65aa168435d6856125b5bdd78
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 RAD51AP2 MFSD2A SUGCT NKAIN1	8.28e-05	167	118	5	40d102e01ccbc7262d00fafd59ca5234909009cb
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMILIN2 PTPRE AP1S2 IRAK3 DHX29	8.51e-05	168	118	5	f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL28A1 ADGRV1 NKAIN2 AP1S2 NKAIN1	8.51e-05	168	118	5	948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Monocytes\|normal_Pleural_Fluid / Location, Cell class and cell subclass	F3 MFSD2A PTPRE IRAK3 CRYBG3	8.75e-05	169	118	5	7b71463f0fd802b422c8d394a435901009ca200f
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|343B / Donor, Lineage, Cell class and subclass (all cells)	TTF2 FLT3 HLA-DOB NRP2 PLEKHO1	8.75e-05	169	118	5	2098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCell	droplet-Kidney-nan-3m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 RAD51AP2 MFSD2A SUGCT NKAIN1	9.00e-05	170	118	5	dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	MECOM ADGRV1 MYO5C PTPRE RASAL2	9.00e-05	170	118	5	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP SLC26A4 TLL2 PTPRQ ABCG5	9.25e-05	171	118	5	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRV1 NKAIN2 HIBADH CYFIP2 OSBPL3	9.51e-05	172	118	5	1565f38266891c3acf49778838de134c5dee5460
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|COVID-19 / Condition, Lineage and Cell class	ZFYVE16 NRP2 MFSD2A PTPRE ZC3H12C	9.77e-05	173	118	5	502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 HLA-DOB PTPRE AP1S2 PLEKHO1	1.00e-04	174	118	5	991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 HLA-DOB PTPRE AP1S2 PLEKHO1	1.00e-04	174	118	5	c8cec89369cf3896c5626e447051e76a142cb6df
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	GRK5 MECOM MYO5C PTPRE PTPRQ	1.00e-04	174	118	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL28A1 MECOM ADGRV1 CYFIP2 OSBPL3	1.03e-04	175	118	5	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB ADGRV1 CSMD3 PTPRQ DTHD1	1.03e-04	175	118	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	EMILIN2 CREB3L4 TLL2 NKAIN1	1.05e-04	92	118	4	0754a79efc4c0659d9a2acfe4185bcae1a3e7206
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	EMILIN2 CREB3L4 TLL2 NKAIN1	1.05e-04	92	118	4	aee1fd2419dc1fc7039c0ac56f0ba23ed11d668f
ToppCell	metastatic_Brain-Myeloid_cells-CD141+_DCs\|metastatic_Brain / Location, Cell class and cell subclass	FLT3 HLA-DOB PTPRE AP1S2 PLEKHO1	1.06e-04	176	118	5	b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCell	droplet-Liver-LIVER-NPC-1m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC26A4 ECH1 HIBADH PHYH HPD	1.09e-04	177	118	5	1b077084b78e62ead603f72c9db6ce74a3953f81
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB AP1M2 DNAJC7 NRP2 PLEKHO1	1.12e-04	178	118	5	0265c0bc005c05fd5906a88c1eafd17891e952f1
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 MECOM TASOR PDE7B RASAL2	1.15e-04	179	118	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP F3 MYO5C OSBPL3 PTPRQ	1.15e-04	179	118	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.18e-04	180	118	5	f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM ADGRV1 NKAIN2 CYFIP2 OSBPL3	1.18e-04	180	118	5	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.18e-04	180	118	5	b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM ADGRV1 NKAIN2 CYFIP2 OSBPL3	1.18e-04	180	118	5	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP F3 MYO5C OSBPL3 PTPRQ	1.21e-04	181	118	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MTHFD1L USP43 MECOM F3 PTPRE	1.21e-04	181	118	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.24e-04	182	118	5	6497eeafb2b137e70261ec0314782831892a940d
ToppCell	Control-Hematopoietic_SC-HSPC\|Control / Disease group, lineage and cell class	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.24e-04	182	118	5	14e347c0e6444410f1948851407bb18c706569f4
ToppCell	Control-Hematopoietic_SC\|Control / Disease group, lineage and cell class	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.24e-04	182	118	5	43243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCell	PBMC-Control-Hematopoietic-HSPC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.24e-04	182	118	5	bd1626261803324084fafca2f6665b50854e7fae
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM ADGRV1 HIBADH CYFIP2 OSBPL3	1.24e-04	182	118	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	F3 CYFIP2 BMP1 MFSD2A C5	1.24e-04	182	118	5	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLGN CDC42BPA MECOM NKAIN2 FBN1	1.24e-04	182	118	5	0d9b8c900da8cbae9cde72aecd4026b1ac2bbd67
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM ADGRV1 HIBADH CYFIP2 OSBPL3	1.27e-04	183	118	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	COVID-19_Severe-Hematopoietic_SC-HSPC\|COVID-19_Severe / Disease group, lineage and cell class	CLGN MECOM NKAIN2 MYO5C FBN1	1.27e-04	183	118	5	4146b1c0e5f76d25226745abfa28f77127a444fc
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PI4K2B DSP HLA-DOB OAS3 PLEKHO1	1.27e-04	183	118	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-cDC1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT3 INPP5F PTPRE AP1S2 PLEKHO1	1.27e-04	183	118	5	661bfc8f5f683b0f4c12bdd359e67c513b181678
ToppCell	COVID-19_Severe-Hematopoietic_SC\|COVID-19_Severe / Disease group, lineage and cell class	CLGN MECOM NKAIN2 MYO5C FBN1	1.27e-04	183	118	5	92aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP F3 MYO5C PTPRQ C5	1.27e-04	183	118	5	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLGN MECOM NKAIN2 MYO5C FBN1	1.30e-04	184	118	5	a6169613c6493b947a176493f542368bfa935dab
Disease	chromosome 15q11.2 deletion syndrome (implicated_via_orthology)	CYFIP2 CYFIP1	4.27e-05	3	112	2	DOID:0060393 (implicated_via_orthology)
Disease	thrombin measurement	TTF2 GRK6	3.94e-04	8	112	2	EFO_0020768
Disease	reading and spelling ability	FLT3 ARFGEF2 MECOM NKAIN2 PHYH	4.38e-04	166	112	5	EFO_0005301
Disease	obsolete_red blood cell distribution width	FLT3 NPR2 AP1M2 MECOM FREM3 F3 MFSD2A GTF2IRD2B CYFIP1 GTF2I ZBED6 GTF2IRD2 PDE7B CLUH	5.87e-04	1347	112	14	EFO_0005192
Disease	Liver Cirrhosis	F3 ARRB1 FBN1 COMMD1	6.51e-04	103	112	4	C0023890
Disease	Fibrosis, Liver	F3 ARRB1 FBN1 COMMD1	7.00e-04	105	112	4	C0239946
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA CCM2	7.68e-04	11	112	2	DOID:0060669 (implicated_via_orthology)
Disease	Sodium measurement	MFRP MFSD2A	7.68e-04	11	112	2	C0337443
Disease	Adverse Event by CTCAE Category	MFRP MFSD2A	7.68e-04	11	112	2	C1879645
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	SLC26A4 TECTA PTPRQ	9.71e-04	51	112	3	cv:CN043650
Disease	cortisol measurement, response to corticosteroid, response to synacthen	GBA3 PDE7B	1.08e-03	13	112	2	EFO_0005843, EFO_0009175, GO_0031960
Disease	coronary artery disease	DAB2IP MTHFD1L USP43 ARFGEF2 MECOM CNPY2 SBK1 BMP1 CCM2 COMMD1 ZBED6 C5	1.95e-03	1194	112	12	EFO_0001645
Disease	citrulline measurement	MECOM PTPRE	2.59e-03	20	112	2	EFO_0009777
Disease	Nonsyndromic genetic hearing loss	SLC26A4 TECTA PTPRQ	3.06e-03	76	112	3	cv:C5680182
Disease	Splenomegaly	FLT3 MECOM	3.14e-03	22	112	2	C0038002
Disease	intraocular pressure measurement	TTF2 TMCO5A RTL10 MECOM MFRP FBN1 PDE7B	3.34e-03	509	112	7	EFO_0004695
Disease	cortical thickness	NPR2 ARFGEF2 MECOM ADGRV1 NRP2 PHYH FBN1 BAZ1A PI4KA TRIM36 CLUH	3.41e-03	1113	112	11	EFO_0004840
Disease	alcohol drinking	SLC26A4 OAS3 F3	3.66e-03	81	112	3	EFO_0004329

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKELAAVCDVFVENY	SUGCT	126	Q9HAC7
KEYAFVTQLCEDQAL	TMCO5A	151	Q8N6Q1
KTIEVFCEYFKELEE	AP1M2	86	Q9Y6Q5
EFFQTEKEFDVLQVY	CSMD3	2501	Q7Z407
FCLEYTSAIFEFKEV	CRYBG3	721	Q68DQ2
CLFEKDDVYQEASLD	BTNL2	341	Q9UIR0
VLDETIQVDCFDSYK	ACVR1	386	Q04771
QFCKVVEETADYVEC	ADGRV1	5871	Q8WXG9
DDYELFCQDLKEVVQ	RTL10	166	Q7L3V2
YVDQLDFCEKEFVSA	ARFGEF2	711	Q9Y6D5
ECSTEVAVYDKDEVF	EAPP	261	Q56P03
DIKETYEVEASTFCF	CCM2	256	Q9BSQ5
TCFDAIIDNFDVYKV	NPR2	891	P20594
TCFDAVIDNFDVYKV	NPR1	906	P16066
EETGFVLEKDSEYCQ	DHX29	771	Q7Z478
SEYCQKFLEEEEEVT	DHX29	781	Q7Z478
FETEGNDVCKYDFVE	BMP1	636	P13497
CFYDIDLDTETEQVK	MTHFD1L	961	Q6UB35
GVDYEVKAFCAENLE	ARRB1	141	P49407
DEEVFYCKVTNEIFR	BAZ1A	21	Q9NRL2
TVEAENIFSKCYEND	RAD51AP2	316	Q09MP3
NSYFEQFKEVLPEDC	INPP4A	831	Q96PE3
ILDEFYNVKFCIDAS	MECOM	126	Q03112
SVCELDIIFNFEKAY	AP1S2	96	P56377
FSLEAQDECKFDYVE	MFRP	346	Q9BY79
IEAEVNLCFDQFVYK	CYFIP1	691	Q7L576
FIKALYESDENCEVD	DAB2IP	441	Q5VWQ8
LEQYEFCYKVVQDFI	PTPRE	676	P23469
FCYKVVQDFIDIFSD	PTPRE	681	P23469
FELYSQFVTLCEKEV	DTD2	116	Q96FN9
IDQDYEFIDYECLAK	KPNA7	501	A9QM74
FYCLYENREEEFVKT	NLRP11	546	P59045
VVCETEEDKFLLLYA	DDX56	236	Q9NY93
VCEEFYRQGELEQKF	PDE7B	341	Q9NP56
YCAQDAFFQVKEVDV	ECH1	186	Q13011
AECFDEITYVELQKE	HNRNPU	646	Q00839
CYVVKCITEEEDSFD	NKAIN2	166	Q5VXU1
FEIEKHDCKYDFIEI	NRP2	76	O60462
FEIAKYCSSDQVEIF	PI4KA	1306	P42356
EFIKALYESDENCEV	RASAL2	396	Q9UJF2
VVVSDDYLQSKECDF	MYD88	221	Q99836
TGEELYVIDENKFVC	LHX5	101	Q9H2C1
EEIINYEFDTKDLVC	HM13	151	Q8TCT9
ELAAYFTETEKFCLI	IRAK3	226	Q9Y616
SDDEFQVDVCAKYTF	OVOS2	221	Q6IE36
EAEVNLCFDQFVYKL	CYFIP2	716	Q96F07
LCFDQFVYKLADQIF	CYFIP2	721	Q96F07
TCYLIDVKSVDNDEF	PTPRQ	1611	Q9UMZ3
FENTYIEACLDFIKD	PANK4	96	Q9NVE7
FVQDLCEDLYELFKT	PI4K2B	391	Q8TCG2
QKDEEVVFCFSSFQV	MFSD2A	76	Q8NA29
IDQYEEFCFSVRFKA	FLT3	361	P36888
IYLPLKVFDNEDFDC	DNAH1	241	Q9P2D7
LFQKICEDFDSYLVQ	COL28A1	976	Q2UY09
EDFVIQAKADCYFTN	HLA-DOB	31	P13765
EAIIESFDKYAQFCF	GBA3	136	Q9H227
GFFYNDKLLVCEDID	FBN1	1796	P35555
SEEVCSFYLKIDTQD	C5	1371	P01031
GLIDYETFKELCEQE	DSP	2486	P15924
GTLKFACESIVEEYE	CNPY2	131	Q9Y2B0
TFQKYCSEILVVNEF	ABCG5	566	Q9H222
FFCEVDEDYIQDKFN	CSNK2B	21	P67870
ELQIKEVDEFGNYSC	DTHD1	596	Q6ZMT9
CVDIKDNVVDEGFYF	DGCR2	271	P98153
KYGQESEFLCLEFDE	COMMD1	151	Q8N668
YYEDCIEKAVQFFVQ	DNAJC7	221	Q99615
TFFKDCLYEVFDDLE	FAM118B	121	Q9BPY3
YEALCKVEAEQNEFI	IFT20	111	Q8IY31
EKNAEEHCFYIEETL	EMILIN2	461	Q9BXX0
IICVTVEDYFNDFAK	EXOC3	571	O60645
AVYCKDVLDIEQFST	GRK5	471	P34947
AIYCKDVLDIEQFST	GRK6	471	P43250
KAEVACIAVYETDVF	GTF2IRD2	41	Q86UP8
KAEVACIAVYETDVF	GTF2IRD2B	41	Q6EKJ0
KAEVACIAVYETDVF	GTF2I	41	P78347
DFQKDFVKYCVEEEE	GTF2I	71	P78347
EKETVAYFCAHFEEQ	INPP5F	351	Q9Y2H2
IKVFDVVFETEDCYV	SBK1	111	Q52WX2
EDFLKLFIDPNEVYC	CREB3L4	66	Q8TEY5
VCVSLKNIVDEDFLY	DCAF15	61	Q66K64
VAKALADDVELYCFQ	CPT1B	536	Q92523
EVCLLFLFKEEEEFT	PRIMPOL	466	Q96LW4
ALYELVKCNFDTEEA	MIER1	256	Q8N108
ETYECIREDKGFQFF	OSBPL3	611	Q9H4L5
ELVIFLDCFKSYVDQ	OAS3	76	Q9Y6K5
VQDFQEDKELFRYCT	PHYH	121	O14832
DDICFKVLYDISEVL	PLA2G4D	101	Q86XP0
ETFCETVQFYLKHLE	MROH2A	226	A6NES4
CLEKEYYIVDEDSTF	FREM3	1776	P0C091
IAFEVEDCDYIVQKA	HPD	96	P32754
DTEEEFKKRAYQCVV	RARS1	281	P54136
YIVNCFLIDDAVVKD	UTP20	426	O75691
YAQEVLKETDQSCFV	TRIM36	351	Q9NQ86
LKDEGFFEYVDILCN	SAMD8	21	Q96LT4
FVFACYVSKVFLEEE	NKAIN1	161	Q4KMZ8
TNEVEECENYFSKTL	NUDT12	111	Q9BQG2
ICLFDITKLEDAYVF	POLR3H	46	Q9Y535
AIVCDFKLFLYDIAE	CDC42BPA	1106	Q5VT25
IQEVFDLSDYEKCEE	PLEKHO1	66	Q53GL0
TVKFYIHEEEESVLC	TASOR	1231	Q9UK61
IIYDVFPDACKEFQD	HIBADH	66	P31937
DIYFDNFIICSEKEV	CLGN	421	O14967
EAKNYFDFDLECETV	CLUH	901	O75153
TINVEFSCAYELDIK	TECTA	1891	O75443
CFIFETFSLDEIKEE	XIRP2	1101	A4UGR9
TLDECFQFYTKEEQL	USP43	541	Q70EL4
FCFQEIEKDIHDFEF	ZNF578	101	Q96N58
QDYVIEKLEQCGFFD	SLC26A4	696	O43511
FDEALVDYFCDEFKT	HSPA4L	236	O95757
QFEVFELEGNDVCKY	TLL2	661	Q9Y6L7
ELEGNDVCKYDFVEV	TLL2	666	Q9Y6L7
EFLIDVDKGENYCFS	F3	206	P13726
ADLETYKQFLAEEVC	ZBED6	786	P86452
FLEEYCKFKNTEDIT	TRIM16	281	O95361
VLDTNKDCEVDFVEY	S100A3	61	P33764
VVCYDDRFIVKLAFE	ZC3H12C	331	Q9C0D7
TCFQEIEKDIHDFVF	ZNF701	151	Q9NV72
YEKVFSCDLEFDEYQ	ZNF529	176	Q6P280
ETDEKIVKCTEVFYF	ZFYVE16	1421	Q7Z3T8
IVKCTEVFYFLKDQD	ZFYVE16	1426	Q7Z3T8
KLSEDEETVYNVFFA	TTF2	846	Q9UNY4
LEEYCKFKNTEDITF	TRIM16L	66	Q309B1
YFLEKVEADELLQAC	KLHL35	251	Q6PF15
FVIQHFADKVEYKCE	MYO5C	546	Q9NQX4