Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	TOP1 DROSHA CHD6 ERCC3 MOV10L1 FAN1	9.08e-05	645	24	6	GO:0140640
GeneOntologyMolecularFunction	vinculin binding	UTRN DMD	1.07e-04	13	24	2	GO:0017166
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	TOP1 CHD6 ERCC3 FAN1	2.50e-04	262	24	4	GO:0140097
GeneOntologyMolecularFunction	helicase activity	CHD6 ERCC3 MOV10L1	8.71e-04	158	24	3	GO:0004386
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	DROSHA FAN1	1.39e-03	46	24	2	GO:0016893
GeneOntologyMolecularFunction	magnesium ion binding	GTPBP10 MOV10L1 FAN1	3.12e-03	247	24	3	GO:0000287
GeneOntologyBiologicalProcess	DNA topological change	TOP1 ERCC3	5.81e-05	10	24	2	GO:0006265
GeneOntologyCellularComponent	dystrophin-associated glycoprotein complex	UTRN DMD	2.37e-04	20	24	2	GO:0016010
GeneOntologyCellularComponent	filopodium membrane	UTRN DMD	2.62e-04	21	24	2	GO:0031527
GeneOntologyCellularComponent	glycoprotein complex	UTRN DMD	3.73e-04	25	24	2	GO:0090665
Domain	Dystrophin	UTRN DMD	1.58e-06	2	24	2	IPR016344
Domain	EF-hand_dom_typ1	UTRN DMD	2.37e-05	6	24	2	IPR015153
Domain	EF-hand_dom_typ2	UTRN DMD	2.37e-05	6	24	2	IPR015154
Domain	EF-hand_2	UTRN DMD	2.37e-05	6	24	2	PF09068
Domain	EF-hand_3	UTRN DMD	2.37e-05	6	24	2	PF09069
Domain	ZF_ZZ_2	UTRN DMD	2.39e-04	18	24	2	PS50135
Domain	ZF_ZZ_1	UTRN DMD	2.39e-04	18	24	2	PS01357
Domain	ZZ	UTRN DMD	2.39e-04	18	24	2	PF00569
Domain	Znf_ZZ	UTRN DMD	2.67e-04	19	24	2	IPR000433
Domain	ZnF_ZZ	UTRN DMD	2.67e-04	19	24	2	SM00291
Domain	Actinin_actin-bd_CS	UTRN DMD	3.94e-04	23	24	2	IPR001589
Domain	ACTININ_2	UTRN DMD	3.94e-04	23	24	2	PS00020
Domain	ACTININ_1	UTRN DMD	3.94e-04	23	24	2	PS00019
Domain	Spectrin	UTRN DMD	3.94e-04	23	24	2	PF00435
Domain	Spectrin_repeat	UTRN DMD	6.29e-04	29	24	2	IPR002017
Domain	Spectrin/alpha-actinin	UTRN DMD	7.67e-04	32	24	2	IPR018159
Domain	SPEC	UTRN DMD	7.67e-04	32	24	2	SM00150
Domain	WW	UTRN DMD	1.65e-03	47	24	2	PF00397
Domain	WW	UTRN DMD	1.72e-03	48	24	2	SM00456
Domain	WW_DOMAIN_2	UTRN DMD	1.94e-03	51	24	2	PS50020
Domain	WW_DOMAIN_1	UTRN DMD	1.94e-03	51	24	2	PS01159
Domain	WW_dom	UTRN DMD	2.02e-03	52	24	2	IPR001202
Domain	CH	UTRN DMD	3.13e-03	65	24	2	SM00033
Domain	CH	UTRN DMD	3.62e-03	70	24	2	PF00307
Domain	-	UTRN DMD	3.73e-03	71	24	2	1.10.418.10
Domain	CH	UTRN DMD	3.93e-03	73	24	2	PS50021
Domain	P-loop_NTPase	GTPBP10 CHD6 ERCC3 MOV10L1 MYO18B	3.94e-03	848	24	5	IPR027417
Domain	CH-domain	UTRN DMD	4.15e-03	75	24	2	IPR001715
Pubmed	Three-dimensional regulation of radial glial functions by Lis1-Nde1 and dystrophin glycoprotein complexes.	UTRN CUX1 DMD	2.78e-07	19	24	3	22028625
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	10525423
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	UTRN DMD	4.56e-07	2	24	2	20434517
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	UTRN DMD	4.56e-07	2	24	2	24337461
Pubmed	Combined gene therapy via VEGF and mini-dystrophin synergistically improves pathologies in temporalis muscle of dystrophin/utrophin double knockout mice.	UTRN DMD	4.56e-07	2	24	2	33987645
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	UTRN DMD	4.56e-07	2	24	2	11297940
Pubmed	Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.	UTRN DMD	4.56e-07	2	24	2	29408646
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	UTRN DMD	4.56e-07	2	24	2	34155298
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	UTRN DMD	4.56e-07	2	24	2	28790199
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	UTRN DMD	4.56e-07	2	24	2	24466085
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	UTRN DMD	4.56e-07	2	24	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	UTRN DMD	4.56e-07	2	24	2	24781208
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	UTRN DMD	4.56e-07	2	24	2	22388933
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	UTRN DMD	4.56e-07	2	24	2	8268660
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	25859846
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	UTRN DMD	4.56e-07	2	24	2	25642938
Pubmed	Activation of non-myogenic mesenchymal stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice.	UTRN DMD	4.56e-07	2	24	2	25859011
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	UTRN DMD	4.56e-07	2	24	2	7731967
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	UTRN DMD	4.56e-07	2	24	2	15703201
Pubmed	Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.	UTRN DMD	4.56e-07	2	24	2	27037492
Pubmed	Microtubule binding distinguishes dystrophin from utrophin.	UTRN DMD	4.56e-07	2	24	2	24706788
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	UTRN DMD	4.56e-07	2	24	2	16710609
Pubmed	Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.	UTRN DMD	4.56e-07	2	24	2	16487708
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	UTRN DMD	4.56e-07	2	24	2	25941878
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	UTRN DMD	4.56e-07	2	24	2	9297964
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	UTRN DMD	4.56e-07	2	24	2	30672725
Pubmed	Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.	UTRN DMD	4.56e-07	2	24	2	21677768
Pubmed	Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice.	UTRN DMD	4.56e-07	2	24	2	10204788
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	UTRN DMD	4.56e-07	2	24	2	25652448
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	UTRN DMD	4.56e-07	2	24	2	28785010
Pubmed	The role of proteases in excitation-contraction coupling failure in muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	25298424
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	UTRN DMD	4.56e-07	2	24	2	7962191
Pubmed	Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.	UTRN DMD	4.56e-07	2	24	2	9713852
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	UTRN DMD	4.56e-07	2	24	2	16307000
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	UTRN DMD	4.56e-07	2	24	2	21949353
Pubmed	Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	25607927
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	UTRN DMD	4.56e-07	2	24	2	8021701
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	UTRN DMD	4.56e-07	2	24	2	23097179
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	UTRN DMD	4.56e-07	2	24	2	26974331
Pubmed	rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.	UTRN DMD	4.56e-07	2	24	2	16819550
Pubmed	Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.	UTRN DMD	4.56e-07	2	24	2	8433092
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	UTRN DMD	4.56e-07	2	24	2	15501597
Pubmed	Second-generation compound for the modulation of utrophin in the therapy of DMD.	UTRN DMD	4.56e-07	2	24	2	25935002
Pubmed	Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.	UTRN DMD	4.56e-07	2	24	2	16024571
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	UTRN DMD	4.56e-07	2	24	2	11257121
Pubmed	Characterization of dystrophin and utrophin diversity in the mouse.	UTRN DMD	4.56e-07	2	24	2	10072426
Pubmed	The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.	UTRN DMD	4.56e-07	2	24	2	9625743
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	UTRN DMD	4.56e-07	2	24	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	UTRN DMD	4.56e-07	2	24	2	7987307
Pubmed	Utility of dystrophin and utrophin staining in childhood muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	16295426
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	UTRN DMD	4.56e-07	2	24	2	11861579
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	UTRN DMD	4.56e-07	2	24	2	18973234
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	UTRN DMD	4.56e-07	2	24	2	30914715
Pubmed	Dystrophin is a microtubule-associated protein.	UTRN DMD	4.56e-07	2	24	2	19651889
Pubmed	Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.	UTRN DMD	4.56e-07	2	24	2	9590295
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	UTRN DMD	4.56e-07	2	24	2	22284942
Pubmed	Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.	UTRN DMD	4.56e-07	2	24	2	29879154
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	UTRN DMD	4.56e-07	2	24	2	17889902
Pubmed	Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	12387876
Pubmed	Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.	UTRN DMD	4.56e-07	2	24	2	12370193
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	UTRN DMD	4.56e-07	2	24	2	27881412
Pubmed	Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.	UTRN DMD	4.56e-07	2	24	2	32025735
Pubmed	Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.	UTRN DMD	4.56e-07	2	24	2	27836895
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	UTRN DMD	4.56e-07	2	24	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	UTRN DMD	4.56e-07	2	24	2	29065908
Pubmed	Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.	UTRN DMD	4.56e-07	2	24	2	31039133
Pubmed	Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.	UTRN DMD	4.56e-07	2	24	2	11796130
Pubmed	BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.	UTRN DMD	4.56e-07	2	24	2	27750047
Pubmed	Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.	UTRN DMD	4.56e-07	2	24	2	8159184
Pubmed	Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.	UTRN DMD	4.56e-07	2	24	2	10679963
Pubmed	TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.	UTRN DMD	4.56e-07	2	24	2	21565990
Pubmed	Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.	UTRN DMD	4.56e-07	2	24	2	17967782
Pubmed	Generation and characterization of transgenic mice with the full-length human DMD gene.	UTRN DMD	4.56e-07	2	24	2	18083704
Pubmed	Expression of the dystrophin-related protein (utrophin) gene during mouse embryogenesis.	UTRN DMD	4.56e-07	2	24	2	8130373
Pubmed	Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.	UTRN DMD	4.56e-07	2	24	2	21062902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	UTRN DMD	4.56e-07	2	24	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	UTRN DMD	4.56e-07	2	24	2	37626761
Pubmed	Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity.	UTRN DMD	4.56e-07	2	24	2	33497702
Pubmed	Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.	UTRN DMD	4.56e-07	2	24	2	8186702
Pubmed	ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice.	UTRN DMD	4.56e-07	2	24	2	28334037
Pubmed	Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.	UTRN DMD	4.56e-07	2	24	2	25940966
Pubmed	Cardiomyopathic features associated with muscular dystrophy are independent of dystrophin absence in cardiovasculature.	UTRN DMD	4.56e-07	2	24	2	12868498
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	UTRN DMD	4.56e-07	2	24	2	15565469
Pubmed	Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.	UTRN DMD	4.56e-07	2	24	2	22266080
Pubmed	Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: evidence for a utrophin-independent mechanism.	UTRN DMD	4.56e-07	2	24	2	17300937
Pubmed	Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.	UTRN DMD	4.56e-07	2	24	2	21768542
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	UTRN DMD	4.56e-07	2	24	2	26516677
Pubmed	Social stress is lethal in the mdx model of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	32192914
Pubmed	Disease course in mdx:utrophin+/- mice: comparison of three mouse models of Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	25921779
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	UTRN DMD	4.56e-07	2	24	2	22209498
Pubmed	α2 and α3 helices of dystrophin R16 and R17 frame a microdomain in the α1 helix of dystrophin R17 for neuronal NOS binding.	UTRN DMD	4.56e-07	2	24	2	23185009
Pubmed	Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.	UTRN DMD	4.56e-07	2	24	2	33359740
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	UTRN DMD	4.56e-07	2	24	2	37108685
Pubmed	Gene expression effects of glucocorticoid and mineralocorticoid receptor agonists and antagonists on normal human skeletal muscle.	UTRN DMD	4.56e-07	2	24	2	28432191
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	UTRN DMD	4.56e-07	2	24	2	10694796
Pubmed	Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.	UTRN DMD	4.56e-07	2	24	2	8171962
Pubmed	Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.	UTRN DMD	4.56e-07	2	24	2	24879867
Pubmed	Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.	UTRN DMD	4.56e-07	2	24	2	27822449
Pubmed	Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition.	UTRN DMD	4.56e-07	2	24	2	36966198
Cytoband	Ensembl 112 genes in cytogenetic band chr20q12	TOP1 CHD6	8.45e-05	26	24	2	chr20q12
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	UTRN DMD	5.12e-05	18	11	2	91
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCAF1 TENM4 STOX1 DMD	2.76e-06	185	24	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GTPBP10 HIF1AN ERCC3	9.26e-05	165	24	3	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCAF1 TENM4 DMD	1.26e-04	183	24	3	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MIGA1 TCAF1 DMD	1.26e-04	183	24	3	351d575339038bd4a66f408da518c567444208e8
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CUX1 TENM4 DMD	1.34e-04	187	24	3	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	SETD5 UTRN CHD6	1.47e-04	193	24	3	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FNBP1 UTRN CUX1	1.47e-04	193	24	3	779276e775cb2492e8dd36436295a536084a6415
ToppCell	normal-na-Myeloid-non-classical_monocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	UTRN CUX1 SNX10	1.47e-04	193	24	3	053adc7ed9f997b503e12239a684bb9f5896e10c
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX1 TENM4 DMD	1.47e-04	193	24	3	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UTRN DMD MYO18B	1.49e-04	194	24	3	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UTRN DMD MYO18B	1.49e-04	194	24	3	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	367C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	FNBP1 CHD6 DMD	1.52e-04	195	24	3	fca958f73de450ef813444d3dc590353f1c55326
ToppCell	ICU-NoSEP-Myeloid-CD16_Mono\|ICU-NoSEP / Disease, Lineage and Cell Type	UTRN CUX1 SNX10	1.54e-04	196	24	3	b15abb1c5396d038bab92b048795020199370f44
ToppCell	mLN-B_cell-B_cell_cycling\|mLN / Region, Cell class and subclass	NLN DROSHA DMD	1.56e-04	197	24	3	806dddcca85c82bd642008d930c8db16b613d88e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX1 TENM4 DMD	1.56e-04	197	24	3	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	mLN-(2)_B_cell-(24)_B_cell_cycling\|mLN / shred on region, Cell_type, and subtype	NLN DROSHA DMD	1.56e-04	197	24	3	70fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCell	Sepsis-ICU-NoSEP-Myeloid-CD16+_Monocyte\|ICU-NoSEP / Disease, condition lineage and cell class	UTRN CUX1 SNX10	1.63e-04	200	24	3	f661e1737be736c62ffb04a45667a65fc3d11e2a
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NLN DROSHA AGPS	1.63e-04	200	24	3	be46efc899d06c55ee297bee3126f69bcdb2048b
Drug	IDETA	UTRN DMD	6.38e-06	4	24	2	CID003036201
Drug	P-20	TOP1 DMD	2.23e-05	7	24	2	CID000017963
Disease	trait in response to apixaban	TENM4 DMD SNX10	1.10e-04	115	24	3	OBA_2050328
Disease	muscular dystrophy (implicated_via_orthology)	UTRN DMD	1.32e-04	21	24	2	DOID:9884 (implicated_via_orthology)
Disease	word list delayed recall measurement, memory performance	CHD6 TENM4	3.30e-04	33	24	2	EFO_0004874, EFO_0006805
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	UTRN DMD	3.93e-04	36	24	2	DOID:11723 (implicated_via_orthology)
Disease	Cutaneous Melanoma	CUX1 ERCC3	5.10e-04	41	24	2	C0151779
Disease	ghrelin measurement	UTRN NLN	7.28e-04	49	24	2	EFO_0600001
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	FNBP1 AGPS	1.52e-03	71	24	2	EFO_0004735, EFO_0007965
Disease	immature platelet count	CUX1 EXOC3L2	3.35e-03	106	24	2	EFO_0803544
Disease	immature platelet fraction	CUX1 EXOC3L2	3.86e-03	114	24	2	EFO_0009187
Disease	Malignant Neoplasms	TOP1 CUX1	4.84e-03	128	24	2	C0006826

Protein segments in the cluster

Peptide	Gene	Start	Entry
FQELQPHFNKLMRRK	EXOC3L2	176	Q2M3D2
PFHKMKQFLSDEQNI	CUX1	606	P39880
MKFRLFQKPANFEQR	DMD	1456	P11532
RKMEFFNPVLNENQK	MOV10L1	736	Q9BXT6
FQNFKPRSNREEMKF	HIF1AN	111	Q9NWT6
QFLVKQMFKRNPSHR	NEK3	231	P51956
LQNPKDFLHLFEKNM	GTPBP10	296	A4D1E9
KQQKEPLSHRFNEFM	FNBP1	361	Q96RU3
FRNKQAQMKHIFTEP	CHD6	351	Q8TD26
MNPNKFRACQFLIKF	ERCC3	536	P19447
KRQQMKIPDGFFAHF	MIGA1	516	Q8NAN2
KFKHLFQQLPEMAVQ	FAN1	761	Q9Y2M0
FQLFQKPANFEQRML	UTRN	1431	P46939
KYNFPQMAHQKRFIE	DROSHA	1331	Q9NRR4
KMFSHQVQKNLAPFF	TCAF1	871	Q9Y4C2
MLRQQFEVNGHFFKK	SETD5	306	Q9C0A6
MDNKQFQFGHALKPQ	AGPS	421	O00116
MLHNFLKREPNQKAF	NLN	681	Q9BYT8
QEMRKHFPQKFQLFN	STOX1	891	Q6ZVD7
RFIRKNKPFLNTQNM	TENM4	1561	Q6N022
LPSKNLFFNMNNRQH	SNX10	76	Q9Y5X0
KEPLVFQNRQFAHLM	MYO18B	2401	Q8IUG5
FNPDNEYHFKNRMKV	USP24	236	Q9UPU5
RVFKNLQLFMENKQP	TOP1	546	P11387