Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 MYO1C CCT3 ERCC6L VWA8 MYO9A ABCA13 MCM6 BPTF DDX46 MYO3B ATP11A RFT1 DNAH6 DNAH9 DYNC1H1 KIFC1 DYNC2H1 ABCB5 CHD7 ORC4

2.42e-0661421121GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 CCT3 ERCC6L VWA8 ABCA13 MCM6 DDX46 ATP11A DNAH6 DNAH9 DYNC1H1 KIFC1 DYNC2H1 ABCB5 CHD7 ORC4

1.97e-0544121116GO:0016887
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH6 DNAH9 DYNC1H1 DYNC2H1

3.30e-05182114GO:0008569
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1C MYO9A MYO3B DNAH6 DNAH9 DYNC1H1 KIFC1 DYNC2H1

3.68e-051182118GO:0003774
GeneOntologyMolecularFunctiondynein intermediate chain binding

SPTBN5 DNAH6 DNAH9 DYNC1H1 DYNC2H1

4.16e-05372115GO:0045505
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

1.11e-0422112GO:0044730
GeneOntologyMolecularFunctionmannosyl-oligosaccharide mannosidase activity

MAN1A1 MAN2A2 EDEM1

1.32e-04102113GO:0015924
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH6 DNAH9 DYNC1H1 DYNC2H1

2.03e-04282114GO:0051959
GeneOntologyMolecularFunctionalpha-mannosidase activity

MAN1A1 MAN2A2 EDEM1

4.82e-04152113GO:0004559
GeneOntologyMolecularFunctionmannosidase activity

MAN1A1 MAN2A2 EDEM1

5.88e-04162113GO:0015923
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ATP11A RFT1

5.88e-04162113GO:0140328
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH6 DNAH9 DYNC1H1 KIFC1 DYNC2H1

8.71e-04702115GO:0003777
DomainATPase_dyneun-rel_AAA

VWA8 DNAH6 DNAH9 DYNC1H1 DYNC2H1

3.01e-07142085IPR011704
DomainAAA_5

VWA8 DNAH6 DNAH9 DYNC1H1 DYNC2H1

3.01e-07142085PF07728
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084IPR024317
DomainDynein_HC_stalk

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084IPR024743
DomainDynein_heavy_dom-2

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084IPR013602
DomainDHC_N2

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084PF08393
DomainMT

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084PF12777
DomainAAA_8

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.37e-05142084PF12780
DomainDHC_fam

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.85e-05152084IPR026983
DomainDynein_heavy

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.85e-05152084PF03028
DomainDynein_heavy_dom

DNAH6 DNAH9 DYNC1H1 DYNC2H1

1.85e-05152084IPR004273
DomainAAA

ABCA1 VWA8 ABCA13 DNAH6 DNAH9 DYNC1H1 DYNC2H1 ABCB5 ORC4

3.44e-051442089SM00382
DomainAAA+_ATPase

ABCA1 VWA8 ABCA13 DNAH6 DNAH9 DYNC1H1 DYNC2H1 ABCB5 ORC4

3.44e-051442089IPR003593
DomainDHC_N1

DNAH9 DYNC1H1 DYNC2H1

7.32e-0582083PF08385
DomainDynein_heavy_dom-1

DNAH9 DYNC1H1 DYNC2H1

7.32e-0582083IPR013594
DomainSerine_rich

NEDD9 BCAR1

3.68e-0432082IPR014928
DomainVitellinogen_superhlx

CAND1 APOB

3.68e-0432082IPR011030
DomainVPS13

VPS13C VPS13A

3.68e-0432082IPR026847
DomainVPS13_mid_rpt

VPS13C VPS13A

3.68e-0432082PF16910
DomainVPS13

VPS13C VPS13A

3.68e-0432082PF16908
DomainVPS13_N2

VPS13C VPS13A

3.68e-0432082IPR031646
DomainVPS13_mid_rpt

VPS13C VPS13A

3.68e-0432082IPR031642
DomainSerine_rich

NEDD9 BCAR1

3.68e-0432082PF08824
DomainSHR-BD

VPS13C VPS13A

7.30e-0442082IPR009543
DomainCAS_DUF3513

NEDD9 BCAR1

7.30e-0442082IPR021901
DomainVPS13_C

VPS13C VPS13A

7.30e-0442082PF16909
DomainVPS13_C

VPS13C VPS13A

7.30e-0442082IPR031645
DomainDUF3513

NEDD9 BCAR1

7.30e-0442082PF12026
DomainSHR-BD

VPS13C VPS13A

7.30e-0442082PF06650
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MAN2A2 MYCBP2 VWA8 OBSCN BIRC6 LYST RYR1 HIRA PCNX2 FAT1 MCM3AP WDR90 GCN1 DYNC1H1 WNK2 SZT2 FBXL14 LAMA5 TLNRD1 AATK COQ4 CTDP1 TANC1 WDFY3 SPATA13

2.68e-0811052152535748872
Pubmed

Network organization of the human autophagy system.

CAND1 CCT3 NEK9 ADSL RAB3GAP2 GCN1 SHMT2 COX15 CBR1 SH3GLB1 GTF3C1 XIRP2 TJP1 TBK1 TMPO

1.11e-074372151520562859
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CCT3 VPS13C OBSCN BIRC6 ERLEC1 RYR1 LRRC47 IGSF10 MYO3B MCM3AP TBC1D14 VPS13A DYNC1H1 IPPK CACNA1F MXRA5 GTF3C1 TBK1 TMPO

1.91e-077362151929676528
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CAND1 CCT3 BIRC6 GTF3C4 LRRC47 BPTF KCTD6 GCN1 VDR RC3H2 PLCD4 CHD7 CCDC141 MTA1 GTF3C1

2.73e-074692151527634302
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UTP6 CAND1 MYO1C CCT3 MYCBP2 MYO9A MCM6 BIRC6 NEK9 GTF3C4 HIRA LRRC47 ADSL MCM3AP UQCRC2 GCN1 DYNC1H1 SHMT2 CHD7 CBR1 IGF2BP2 C5orf24 GTF3C1 TANC1 WDFY3 CDC20

3.37e-0713532152629467282
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MAN2A2 MYCBP2 OBSCN BIRC6 NEK9 RYR1 NEDD9 VAV2 VWF CCDC141 SH3GLB1 AKAP9 XIRP2 TBK1 ANKRD1

5.68e-074972151523414517
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UTP6 MYO1C CCT3 MYCBP2 MCM6 BIRC6 LRRC47 BPTF DDX46 MCM3AP UQCRC2 GCN1 DYNC1H1 CHD7 IGF2BP2 GTF3C1 TJP1

7.70e-076532151722586326
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NMNAT2 CAND1 VWA8 VPS13C LRRC47 DDX46 SEMA5B WDR90 WNK2 ACAP3 PDPR SZT2 LAMA5 EDEM1 EXOSC7

1.23e-065292151514621295
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

CAND1 MYO1C MYCBP2 VWA8 MCM6 GTF3C4 VPS13A LRRC41 SZT2 DYNC2H1 CIP2A SHMT2 COX15 TBK1 DNAJC11 TMPO

1.37e-066062151636538041
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MAGOH MYO1C CCT3 MYCBP2 VWA8 VPS13C BIRC6 SPTBN5 ADSL RAB3GAP2 CCDC138 VPS13A DNAJC1 UQCRC2 PDPR CIP2A SHMT2 COX15 IGF2BP2 CRYZ AKAP9 DNAJC11 TMPO TANC1 CDC20 GFM1

2.18e-0614962152632877691
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

UTP6 KNTC1 CAND1 MYO1C CCT3 VPS13C MCM6 NEK9 LRRC47 ADSL RAB3GAP2 UQCRC2 GCN1 DYNC1H1 KIFC1 DYNC2H1 ANXA2 SHMT2 APOB CBR1 GTF3C1 TBK1 DNAJC11 TMPO GFM1

2.94e-0614252152530948266
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

UTP6 CAND1 MCM6 GTF3C4 DDX46 GCN1 ORC4 MTA1 TMPO

3.85e-06195215919454010
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

MAN2A2 VWA8 AVL9 GTF3C4 ITIH2 LRRC47 DDX46 MCM3AP UQCRC2 GCN1 DYNC1H1 TMED1 RC3H2 ANXA2 SHMT2 APOB CHD7 IGF2BP2 CRYZ AKAP9 TJP1 TBK1 TMPO CDC20

4.89e-0613712152436244648
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

CCT3 LRRC47 BPTF GCN1 DYNC1H1 NID2 ANXA2 ANXA2P2 TMPO

5.34e-06203215922083510
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

MCM6 BIRC6 NEK9 LRRC47 ADSL RAB3GAP2 GCN1 DYNC1H1 ORC4 IGF2BP2 MTA1 GTF3C1 TMPO GFM1

6.88e-065342151435032548
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

CCT3 MYO9A NEK9 GTF3C4 GCN1 DYNC1H1 IGF2BP2 GTF3C1 TMPO

7.29e-06211215917314511
Pubmed

Structure and chromosome assignment of the murine p36 (calpactin I heavy chain) gene.

NCAM1 ANXA2 ANXA2P2

8.01e-06721532138915
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYO1C CCT3 MYCBP2 BIRC6 KIAA0753 CCDC138 VPS13A PPP1R9B UQCRC2 GCN1 PDPR CIP2A FBXL14 SHMT2 BCAR1 IGF2BP2 AKAP9 TJP1 TMPO TANC1

9.32e-0610492152027880917
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CAND1 CCT3 MYCBP2 NCAM1 NEK9 HIRA SLC12A5 PPP1R9B NOS1 DYNC1H1 WNK2 RAPGEF4 CHD7 AKAP9 TJP1 TBK1 WDFY3 UNC13A SPATA13

9.78e-069632151928671696
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

CCT3 VWA8 GCN1 NID2 ANXA2 LAMA5 SHMT2 MTA1 GTF3C1

9.83e-06219215931353912
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ABCA13 CARMIL3 LYST RYR1 FAT1 VPS13A VWF SZT2 MUC16 CPZ CHD7 GUCY2C TJP1 TENM1

9.99e-065522151410737800
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KNTC1 SPAG1 MYO1C CCT3 DZIP1L MMP21 LYST ERLEC1 BPTF VPS13A PPP1R9B ATP11A UQCRC2 DNAH6 ANXA2 ABCB5 APOB GTF3C1 TJP1 DNAJC11 TENM1 TMPO CCDC158 SPATA13

1.13e-0514422152435575683
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

CAND1 MYO1C CCT3 MYCBP2 MCM6 BIRC6 NEK9 GTF3C4 LRRC47 ADSL UQCRC2 GCN1 DYNC1H1 LRRC41 ANXA2 ANXA2P2 SHMT2 COX15 GTF3C1 DNAJC11 TMPO GFM1

1.25e-0512572152237317656
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

KNTC1 ERCC6L MYCBP2 VPS13C BIRC6 ERLEC1 GTF3C4 RAB3GAP2 DNAJC1 CIP2A MFSD9 CHD7 TJP1 TANC1 CDC20 GFM1

1.50e-057332151634672954
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NEK9 NEDD9 WDR90 DYNC1H1 WNK2 CHD7 BCAR1 CCDC141 MTA1 AATK XIRP2 NBPF9

1.71e-054302151235044719
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AREL1 TBC1D14 GCN1 AATK TANC1 WDFY3

1.73e-0587215612465718
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CAND1 MAN1A1 MYO1C CCT3 VPS13C RYR1 FAT1 DYNC1H1 MXRA5 VWF DYNC2H1 ANXA2 GPT LAMA5 SHMT2 PKD1L3 CBR1 CRYZ CTH

2.05e-0510162151919056867
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

ABCA1 VWA8 BIRC6 VPS13A TMEM65 PDPR SHMT2 COX15 CBR1 GTF3C1 TBK1 DNAJC11 GFM1

2.19e-055152151331617661
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

UTP6 CAND1 CCT3 MYCBP2 MCM6 BPTF DDX46 UQCRC2 GCN1 DYNC1H1 KIFC1 ANXA2 SHMT2 CBR1 IGF2BP2 GTF3C1 TJP1 TBK1 TMPO

2.28e-0510242151924711643
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

CCT3 SPTBN5 SEMA5B ZNF616 DNAH6 MXRA5 DYNC2H1 CIP2A

2.32e-05187215826460568
Pubmed

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

CAND1 MYO1C CCT3 DDX46 GCN1 ANXA2 APOB DNAJC11 TMPO

2.32e-05244215928902428
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

UTP6 CAND1 MAN1A1 ERCC6L MCM6 ERLEC1 LRRC47 RAB3GAP2 RFT1 GCN1 DYNC1H1 DYNC2H1 CIP2A SPAG5 TBK1 DNAJC11 TMPO CTH

2.57e-059422151831073040
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ERCC6L MYCBP2 MYO9A PAK6 LYST NEK9 KIAA0753 RAB3GAP2 CCDC138 STIL BCAR1 AKAP9 TJP1 OTUD7A TANC1 CDC20 SPATA13

2.89e-058612151736931259
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CAND1 MYO1C CCT3 VPS13C NCAM1 BIRC6 FAT1 VPS13A GCN1 SDK1 DYNC1H1 MUC16 APOB AP4E1 TJP1 TMPO

3.03e-057772151635844135
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

CAND1 MYO9A PKD1L2 RAB3GAP2 FDXR DYNC1H1 DYNC2H1 ABCB5 AP4E1 CRYZ

3.56e-053222151026514267
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

UTP6 CCT3 MCM6 BIRC6 GTF3C4 LRRC47 RAB3GAP2 FDXR UQCRC2 GCN1 DYNC1H1 PDPR SHMT2 IGF2BP2 GTF3C1

3.66e-057042151529955894
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

3.80e-052215223148505
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

3.80e-05221523013423
Pubmed

Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.

ABCA1 APOB

3.80e-052215228694219
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

3.80e-052215217549680
Pubmed

Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy.

TBK1 PRKN

3.80e-052215233164878
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

3.80e-052215239384746
Pubmed

Genetic analysis of the cytoplasmic dynein subunit families.

DYNC1H1 DYNC2H1

3.80e-052215216440056
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

3.80e-052215219841537
Pubmed

Variable phenotype of del45-55 Becker patients correlated with nNOSμ mislocalization and RYR1 hypernitrosylation.

RYR1 NOS1

3.80e-052215222589245
Pubmed

Whole-exome sequencing of consanguineous families with infertile men and women identifies homologous mutations in SPATA22 and MEIOB.

MEIOB SPATA22

3.80e-052215234392356
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

3.80e-052215222185818
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

3.80e-052215221486955
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

3.80e-052215219580511
Pubmed

Oscillation of Cdc20-APC/C-mediated CAMDI stability is critical for cortical neuron migration.

CCDC141 CDC20

3.80e-052215234298015
Pubmed

Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22.

MEIOB SPATA22

3.80e-052215236331299
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

3.80e-052215236739096
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

3.80e-052215222517898
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

3.80e-052215230462534
Pubmed

Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.

DYNC1H1 DYNC2H1

3.80e-052215225502651
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

3.80e-052215221572519
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.

ANXA2 ANXA2P2

3.80e-052215237832154
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

3.80e-052215230902828
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

3.80e-052215232687500
Pubmed

ZO-1 and IL-1RAP Phosphorylation: Potential Role in Mediated Brain-Gut Axis Dysregulation in Irritable Bowel Syndrome-like Stressed Mice.

TJP1 IL1RAP

3.80e-052215239006851
Pubmed

Effect of endogenous hydrogen sulfide on the transwall gradient of the mouse colon circular smooth muscle.

NOS1 CTH

3.80e-052215224366262
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

3.80e-052215220607799
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

3.80e-052215231253864
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

3.80e-052215219628708
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

3.80e-052215220847146
Pubmed

Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks.

MEIOB SPATA22

3.80e-052215228453612
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

3.80e-052215219536308
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

3.80e-052215238290972
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

3.80e-052215235064931
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

3.80e-052215228130864
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

3.80e-052215220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

3.80e-052215227468426
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

3.80e-052215227389701
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

3.80e-052215217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

3.80e-052215219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

3.80e-052215219022301
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

3.80e-052215238253182
Pubmed

Repression of neuronal nitric oxide (nNOS) synthesis by MTA1 is involved in oxidative stress-induced neuronal damage.

NOS1 MTA1

3.80e-052215227603575
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

3.80e-052215221737841
Pubmed

Identification of gene markers for the prediction of allograft rejection or permanent acceptance.

MAN1A1 TCAIM

3.80e-052215217456197
Pubmed

Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.

VPS13C VPS13A

3.80e-052215217196930
Pubmed

Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium.

ABCA1 APOB

3.80e-052215230076206
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

3.80e-052215238092984
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

3.80e-052215221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

3.80e-052215227371724
Pubmed

Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes.

PKD1L2 PKD1L3

3.80e-052215212782129
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

3.80e-052215231817350
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

3.80e-052215224742684
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

3.80e-052215222453828
Pubmed

PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.

APOB PCSK7

3.80e-052215237967646
Pubmed

Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.

ANXA2 ANXA2P2

3.80e-052215215654879
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

MYCBP2 MYO9A KIAA0753 CCDC138 STIL SPAG5

4.05e-05101215624613305
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ERCC6L MYCBP2 NEK9 GTF3C4 BPTF DDX46 RAB3GAP2 GCN1 DYNC1H1 ANXA2 GTF3C1 TJP1 TMPO

4.22e-055492151338280479
Pubmed

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.

MYCBP2 KCTD6 DYNC1H1

4.92e-0512215329293652
Pubmed

Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians.

VDR TLR9 PRKN

4.92e-0512215319723394
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

OBSCN MCM6 RYR1 SPTBN5 SDK1 WNK2 ANXA2 LAMA5

6.02e-05214215822199357
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 BIRC6 NEK9 GTF3C4 RAB3GAP2 GCN1 CIP2A CHD7 SPAG5 GTF3C1 TBK1

6.52e-054182151134709266
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH6 DYNC1H1 DYNC2H1

8.06e-051421539373155
Pubmed

Enhancer interaction networks as a means for singular olfactory receptor expression.

OR4E1 NCAM1 BPTF

8.06e-0514215325417106
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

CAND1 ERCC6L MCM6 GTF3C4 RAB3GAP2 PPP1R9B SPATA22 DYNC1H1 ANAPC4 LRRC41 DYNC2H1 GTF3C1 TMPO CDC20

8.19e-056702151422990118
InteractionEED interactions

UTP6 KNTC1 MAGOH CAND1 MAN1A1 MYO1C CCT3 MYCBP2 VPS13C OBSCN MCM6 BIRC6 NEK9 GTF3C4 BPTF RAB3GAP2 PPP1R9B UQCRC2 DYNC1H1 NID2 SZT2 CIP2A LAMA5 COX15 CHD7 CBR1 IGF2BP2 MTA1 GTF3C1 XIRP2 TJP1 UNC45B TBK1 TMPO PRKN TANC1

4.83e-07144520536int:EED
Cytoband16p12

SCNN1G UQCRC2 GTF3C1

3.55e-0514215316p12
GeneFamilyCas scaffolding proteins

NEDD9 BCAR1

3.29e-0441352469
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 OBSCN PKD1L2 FAT1 DNAH9 SDK1 CACNA1F APOB XIRP2 TENM1 CNTNAP4

1.69e-09184215112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 OBSCN PKD1L2 FAT1 DNAH9 SDK1 CACNA1F APOB XIRP2 TENM1 CNTNAP4

1.69e-09184215112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 OBSCN PKD1L2 FAT1 DNAH9 SDK1 CACNA1F APOB XIRP2 TENM1 CNTNAP4

1.69e-0918421511ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 DZIP1L EFHB WDR90 DNAH6 DNAH9 DYNC2H1 TOGARAM2 MUC16 RFX3

2.94e-09194215114a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 MYCBP2 CARMIL3 VPS13C VPS13A DYNC1H1 VDR DYNC2H1 RAPGEF4 AKAP9 SEZ6L

3.10e-09195215117796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 MYCBP2 CARMIL3 VPS13C VPS13A DYNC1H1 VDR DYNC2H1 RAPGEF4 AKAP9 SEZ6L

3.10e-09195215113e519cffa6144a62b06124642a14c9ff39b76554
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 DZIP1L EFHB DNAH6 DNAH9 WHRN DYNC2H1 TOGARAM2 MUC16 RFX3

1.04e-081692151014aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 DZIP1L EFHB DNAH6 DNAH9 DYNC2H1 MUC16 RFX3 AKAP9

4.45e-081972151022c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 DZIP1L EFHB DNAH6 DNAH9 DYNC2H1 MUC16 RFX3 AKAP9

4.45e-08197215103bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 DZIP1L EFHB DNAH6 DNAH9 DYNC2H1 MUC16 RFX3 AKAP9

4.45e-081972151087db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KNTC1 ERCC6L CENPL MCM6 CIP2A STIL SPAG5 TMPO CDC20

2.54e-071812159e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KNTC1 ERCC6L CENPL MCM6 CIP2A STIL SPAG5 TMPO CDC20

2.54e-0718121592be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ERCC6L CENPL KIFC1 CIP2A TLR9 STIL SPAG5 CDC20

3.65e-071892159bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ERCC6L CENPL KIFC1 CIP2A TLR9 STIL SPAG5 CDC20

3.65e-07189215996f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 WNK2 CCDC141 XIRP2 PRKN RNF207

3.65e-0718921595e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CAND1 AVL9 BIRC6 GTF3C4 BPTF DYNC1H1 ZNF260 AKAP9 WDFY3

4.36e-071932159abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPAG1 ERCC6L ABCA13 WDR90 DYNC2H1 TMC4 STIL RFX3 CDC20

4.55e-0719421595dffa578149104dda33774361e9e77b227b5f1ce
ToppCellmedial-2-Hematologic-IGSF21+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC12A5 FMN1 TBC1D14 SLC37A2 MS4A6A VDR CYSLTR2 OLFML2B PKD1L3

4.75e-071952159bb612979360b2322289545dda3d3c343d005ee6f
ToppCellmedial-Hematologic-IGSF21+_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC12A5 FMN1 TBC1D14 SLC37A2 MS4A6A VDR CYSLTR2 OLFML2B PKD1L3

4.75e-071952159779130c2cfcbc603955b0c0332b855b22ab6e9e6
ToppCellmedial-Hematologic-IGSF21+_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC12A5 FMN1 TBC1D14 SLC37A2 MS4A6A VDR CYSLTR2 OLFML2B PKD1L3

4.75e-071952159330b688d703d53cb7feb29373b5a6e6e529169ec
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 EFHB DNAH6 DNAH9 DYNC2H1 MUC16 RFX3 AKAP9

5.17e-07197215991637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L WDR90 DNAH6 DNAH9 DYNC2H1 TOGARAM2 RFX3 IGF2BP2 AKAP9

5.17e-07197215974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KNTC1 ERCC6L CENPL MEIOB KIFC1 CIP2A STIL SPAG5 CDC20

5.63e-071992159be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KNTC1 ERCC6L MEIOB KIFC1 CIP2A STIL SPAG5 TMPO CDC20

5.87e-0720021594cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KNTC1 ERCC6L CENPL MEIOB KIFC1 STIL SPAG5 TMPO CDC20

5.87e-0720021599bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

KNTC1 ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

5.87e-0720021597e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

KNTC1 ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

5.87e-0720021599775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

MYO9A VPS13C NEDD9 PHKA2 SCNN1G ATP11A CACNA1F CHD7 RNF207

5.87e-0720021592dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

CENPL MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

1.97e-0617221588d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METAP1D TCAIM WDR90 SMOX WNK2 PLCD4 LHCGR

2.29e-061232157a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

REG4 BPIFB3 ABCB5 RAPGEF4 IGF2BP2 ANKRD1

2.49e-068021563413ac5e1c1e59eab6a83b889b870a8db4efccb9
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L EFHB DNAH6 DNAH9 SDK1 DYNC2H1 TOGARAM2 RFX3

2.64e-0617921585e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN NCAM1 WNK2 CCDC141 XIRP2 UNC45B ANKRD1 PRKN

3.38e-061852158549eeb521c3985bff396ea0f202db21822efa51f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 CCDC141 XIRP2 ANKRD1 PRKN

3.38e-0618521586baccb26f999145e51b91d94315bf8d4655bef31
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

METAP1D FAT1 NOS1 SDK1 VAV2 TOGARAM2 MYRFL RASGRP2

3.52e-06186215877592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 PAK6 RYR1 MS4A6A KIFC1 CIP2A STIL CDC20

3.66e-06187215873931a5ea73799095daff100b5f18853c57c74dc
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 WNK2 CCDC141 XIRP2 RNF207

3.80e-0618821580758b474457efa36488e0195f7357100f4b6a090
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

ERCC6L CENPL KIFC1 CIP2A STIL SPAG5 TMPO CDC20

3.80e-061882158b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 WNK2 CCDC141 PRKN RNF207

4.11e-061902158de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO3B SDK1 VAV2 TOGARAM2 MYRFL LGI2 TENM1 TANC1

4.11e-0619021580acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 WNK2 CCDC141 PRKN RNF207

4.11e-061902158fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 WDR90 DNAH6 DNAH9 STIL SLC47A2 CDC20

4.28e-061912158683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L CENPL WNK2 CIP2A STIL SPAG5 TMPO CDC20

4.44e-06192215852d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

VWA8 OBSCN NCAM1 TMEM65 WNK2 CCDC141 ANKRD1 TANC1

4.44e-061922158ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 DZIP1L EFHB IGSF10 DNAH6 DNAH9 SDK1 DYNC2H1

4.62e-061932158ea345d34440b25f65358a53dc72831998d1c3620
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NCAM1 FAT1 MXRA5 OLFML2B RAPGEF4 TMEM98 TJP1 TANC1

4.62e-0619321585e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

ABCA1 RYR1 FMN1 TBC1D14 SMOX MS4A6A VAV2 CYSLTR2

4.80e-061942158800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

4.80e-0619421584d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L EFHB DNAH6 DNAH9 DYNC2H1 TOGARAM2 RFX3 KCNRG

4.98e-0619521583486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 EFHB DNAH6 DNAH9 DYNC2H1 MUC16 RFX3

4.98e-0619521589651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 CDC20

4.98e-061952158c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

4.98e-06195215893c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CARMIL3 METAP1D FAT1 NOS1 SDK1 VAV2 LGI2 TENM1

5.17e-0619621587af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERCC6L CENPL KIFC1 CIP2A STIL SPAG5 TMPO CDC20

5.37e-0619721587eb4c1cffd0366204af7e63adc8f751685601a94
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NCAM1 FAT1 DIO2 MXRA5 OLFML2B TMEM98 OTUD7A TANC1

5.37e-0619721582f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KNTC1 ERCC6L CENPL KIFC1 CIP2A STIL SPAG5 CDC20

5.57e-061982158da6963184c32761c896a9b91a5321ad84b583736
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L EFHB DNAH6 DNAH9 DYNC2H1 TOGARAM2 RFX3 KCNRG

5.57e-061982158ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KNTC1 ERCC6L CENPL KIFC1 CIP2A STIL SPAG5 CDC20

5.57e-06198215864a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KNTC1 ERCC6L CENPL KIFC1 CIP2A STIL SPAG5 CDC20

5.57e-061982158fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

KNTC1 ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 CDC20

5.78e-06199215847c47ebc318a0b98841ca2656837bbd068899559
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

KNTC1 CCT3 MCM6 KIFC1 SHMT2 STIL SPAG5 CDC20

5.78e-0619921586748d4f76703360071d5f2026d9d06bf30ccfb6d
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

KNTC1 ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 CDC20

5.78e-061992158c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KNTC1 ERCC6L CENPL KIFC1 STIL SPAG5 TMPO CDC20

5.78e-06199215898575fcce726589e93fbb4df1aab03e57cb56076
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

UTP6 KNTC1 CENPL AVL9 ATP11A CIP2A STIL SPAG5

5.78e-061992158b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellTCGA-Lung-Primary_Tumor|TCGA-Lung / Sample_Type by Project: Shred V9

KNTC1 CCT3 MCM6 KIFC1 SHMT2 STIL SPAG5 CDC20

5.78e-061992158d1d035e987280607266171094db5d6362efe1ad5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO9A NEDD9 SCNN1G ATP11A CACNA1F NID2 CHD7 RNF207

5.78e-061992158d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

UTP6 KNTC1 CENPL AVL9 ATP11A CIP2A STIL SPAG5

5.78e-06199215838f1f612b29feb868322999ceeda78e52447ec4f
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO9A NEDD9 SCNN1G ATP11A CACNA1F NID2 CHD7 RNF207

6.00e-0620021588683445ad5b70748c4a1f12eb77d47623085147e
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

EFHB WDR90 DNAH6 DNAH9 DYNC2H1 TOGARAM2 RFX3 KCNRG

6.00e-0620021583305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

CENPL KIAA0753 FDXR KIFC1 IPPK STIL PKD1L3 CDC20

6.00e-0620021586e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KNTC1 MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

6.00e-062002158f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

CENPL KIAA0753 FDXR KIFC1 IPPK STIL PKD1L3 CDC20

6.00e-0620021589769185abae084ffac36420c749625e679b70ca8
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KNTC1 MEIOB MCM6 KIFC1 CIP2A STIL SPAG5 CDC20

6.00e-0620021589c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KNTC1 MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

6.00e-06200215804bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

CENPL KIFC1 CIP2A CHD7 SPAG5 TMEM98 TMPO CDC20

6.00e-062002158971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellCOVID-19-Lymphoid-Proliferating_CD8_T_cells|COVID-19 / Condition, Lineage and Cell class

ERCC6L MCM6 KIFC1 CIP2A STIL SPAG5 TMPO CDC20

6.00e-062002158b239c711cce967826432fdbd5f88eba98a88bb0c
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SPAG1 NUP210L FAT1 DYNC1H1 PLCD4 TJP1 ANKRD1

6.51e-0614421570b94d978262a826c9254145aa98c6c30240243f9
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 ERCC6L CENPL KIFC1 STIL SPAG5 CDC20

1.46e-0516321575285318c52aa31c9b22dc2ffff078e32e408604d
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 NMNAT2 KIFC1 CIP2A STIL SPAG5 CDC20

1.58e-05165215796f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ERCC6L MCM6 AWAT2 XCR1 CIP2A SPAG5

1.78e-05168215796f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCell(05)_Ciliated-(3)_72hpi|(05)_Ciliated / shred by cell type and Timepoint

KIFC1 WHRN STIL SLC47A2 SPAG5 CDC20

1.83e-051132156eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 ERCC6L KIFC1 CIP2A STIL SPAG5 CDC20

1.85e-051692157e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ABCA1 NEDD9 VWF LAMA5 TJP1 ANKRD1 TANC1

1.92e-051702157e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN NCAM1 FMN1 WNK2 CCDC141 XIRP2 ANKRD1

1.92e-0517021573f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

OBSCN NCAM1 FMN1 MS4A6A CCDC141 XIRP2 ANKRD1

1.92e-0517021574232fe937909f93d3736988c707b8f95ce993398
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPL MMP21 KIFC1 KCTD19 CIP2A STIL CDC20

1.99e-051712157c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ERCC6L MCM6 AWAT2 XCR1 CIP2A SPAG5

2.15e-05173215720a20429aa898097d5ec4880ed64846558b5890f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 ERCC6L KIFC1 KCTD19 CIP2A STIL CDC20

2.23e-051742157dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 ERCC6L MCM6 XCR1 CIP2A SPAG5 CDC20

2.31e-051752157a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 MYO9A IGF2BP2 AATK ANKRD1 WDFY3 CCDC158

2.40e-0517621575e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 CENPL VAV2 KIFC1 CIP2A SPAG5 CDC20

2.49e-051772157e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 CENPL VAV2 KIFC1 CIP2A SPAG5 CDC20

2.49e-0517721578a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 MCM6 PAK6 KIFC1 CIP2A STIL TMPO

2.67e-05179215788d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 EFHB SCNN1G DNAH6 DNAH9 WNK2 KCNRG

2.67e-0517921571c41314b6fcfcac8d62034e7037570120d58f20f
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPL KIFC1 CIP2A STIL SPAG5 TMPO CDC20

2.77e-0518021575e1680088065be14447d5d5465f91f7edd071a1e
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 ERCC6L CENPL KIFC1 STIL SPAG5 CDC20

2.77e-051802157334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

DZIP1L MS4A6A KIFC1 OR10P1 OLFML2B WDFY3 CDC20

2.77e-0518021574eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 EFHB WDR90 DNAH6 DNAH9 DYNC2H1 SLC47A2

2.77e-0518021571f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KNTC1 CENPL CIP2A STIL SPAG5 TMPO CDC20

2.87e-0518121570c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KNTC1 CENPL CIP2A STIL SPAG5 TMPO CDC20

2.87e-051812157f83565f09dd971c5cad2704a4a86bca0accd955e
DiseaseColorectal Carcinoma

ABCA1 ABCA13 SLC22A15 OBSCN PAK6 SLC12A5 LRRC47 FAT1 GDAP1L1 MCM3AP VPS13A SCNN1G UQCRC2 ANAPC4 ABCB5 APOB TLR9 AKAP9 GUCY2C TENM1

1.58e-0770220920C0009402
DiseaseParkinson's disease 23 (implicated_via_orthology)

VPS13C VPS13A

4.99e-0522092DOID:0060896 (implicated_via_orthology)
Diseasechoreaacanthocytosis (implicated_via_orthology)

VPS13C VPS13A

4.99e-0522092DOID:0050766 (implicated_via_orthology)
DiseaseX-11795 measurement

MCM6 CTH

1.49e-0432092EFO_0021261
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13C VPS13A

1.49e-0432092DOID:0111611 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13A

1.49e-0432092DOID:0111590 (implicated_via_orthology)
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

LYST WDFY3

2.97e-0442092DOID:2935 (implicated_via_orthology)
DiseasePolyneuropathy

EPO NMNAT2

2.97e-0442092C0152025
Diseaseaortic valve stenosis (is_implicated_in)

VDR APOB

4.92e-0452092DOID:1712 (is_implicated_in)
Diseasefamilial combined hyperlipidemia (is_marker_for)

VWF APOB

7.35e-0462092DOID:13809 (is_marker_for)
Diseasenon-alcoholic fatty liver disease (is_marker_for)

VDR GPT TLR9

9.04e-04272093DOID:0080208 (is_marker_for)
DiseaseLDL cholesterol change measurement

APOB PKD1L3

1.02e-0372092EFO_0007804
Diseaseasphyxiating thoracic dystrophy (is_implicated_in)

KIAA0753 DYNC2H1

1.02e-0372092DOID:0050592 (is_implicated_in)
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

ABCA1 APOB PCSK7 CEACAM20

1.32e-03672094EFO_0008595, EFO_0020946
Diseaseglucagon-like peptide-1 measurement, glucose tolerance test

GPT RAPGEF4

1.36e-0382092EFO_0004307, EFO_0008465
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C VPS13A

1.36e-0382092DOID:0050753 (implicated_via_orthology)
Diseasefear of minor pain measurement

TMEM65 TENM1 PRKN

1.36e-03312093EFO_0008340
Diseaseuric acid measurement

ABCA1 REG4 MYO9A BIRC6 FMN1 RFT1 ANAPC4 IPPK DYNC2H1 ORC4 IGF2BP2 TANC1

1.45e-0361020912EFO_0004761
Diseasecystic fibrosis (implicated_via_orthology)

ABCB5 EDEM1

1.74e-0392092DOID:1485 (implicated_via_orthology)
DiseaseSpastic Paraplegia

LYST RAB3GAP2

1.74e-0392092C0037772
DiseaseSitus ambiguous

MMP21 DNAH9

1.74e-0392092C1167664
DiseaseParkinson's disease (is_implicated_in)

EPO NOS1 VDR PRKN

2.11e-03762094DOID:14330 (is_implicated_in)
Diseasevisceral heterotaxy (implicated_via_orthology)

MMP21 PHKA2 RFX3

2.28e-03372093DOID:0050545 (implicated_via_orthology)
DiseaseSitus Inversus

MMP21 DNAH9

2.63e-03112092C0037221
Diseaseattention deficit hyperactivity disorder, conduct disorder

PKD1L2 MYRFL PKD1L3

2.85e-03402093EFO_0003888, EFO_0004216
Diseasepeptic esophagitis (biomarker_via_orthology)

TJP1 IL5

3.14e-03122092DOID:13976 (biomarker_via_orthology)
Diseasemiddle cerebral artery infarction (is_implicated_in)

EPO NCAM1

3.14e-03122092DOID:3525 (is_implicated_in)
Diseaseretinopathy of prematurity (biomarker_via_orthology)

EPO NOS1

3.14e-03122092DOID:13025 (biomarker_via_orthology)
Diseaseresponse to ketamine, dissociation measurement

GDAP1L1 TOGARAM2

3.70e-03132092EFO_0009748, EFO_0009750
DiseaseHyperlipoproteinemia Type IIb

ABCA1 APOB

3.70e-03132092C1704417
Diseaseleft ventricular systolic function measurement

MYO1C OBSCN CCDC141

3.75e-03442093EFO_0008206
Diseaseschizophrenia (is_marker_for)

NCAM1 PPP1R9B VWF

3.75e-03442093DOID:5419 (is_marker_for)
Diseasebody weight

KNTC1 MAN1A1 VPS13C PAK6 ERLEC1 BPTF ADSL ANAPC4 IPPK NID2 CHD7 RFX3 KCNRG LHCGR IGF2BP2 AATK FEZ2 CNTNAP4

3.91e-03126120918EFO_0004338
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

PKD1L2 NEDD9 ABCB5

4.25e-03462093EFO_0005325, HP_0012735
Diseasetriacylglycerol 54:4 measurement

SDK1 APOB CTH

4.25e-03462093EFO_0010422
DiseaseMalignant neoplasm of breast

OBSCN SEMA5B SMOX DNAH9 VDR TMED1 NID2 VWF DYNC2H1 MFSD9 FAM131A BCAR1 LHCGR AKAP9 UNC45B TENM1

4.29e-03107420916C0006142
Diseaserespiratory quotient

AATK UNC13A

4.30e-03142092EFO_0005189
DiseaseT wave morphology measurement

OLFML2B RNF207

4.30e-03142092EFO_0008398
Diseaserenal cell carcinoma (biomarker_via_orthology)

ANXA2 ANXA2P2

4.30e-03142092DOID:4450 (biomarker_via_orthology)
DiseaseKidney Failure, Chronic

EPO ABCA1 CBR1

4.79e-03482093C0022661
DiseaseSitus ambiguus

MMP21 DNAH9

4.93e-03152092C0266642
Diseasehepcidin:transferrin saturation ratio

KCTD6 MUC16

4.93e-03152092EFO_0007902
Diseaseapolipoprotein B to apolipoprotein A1 ratio

APOB PCSK7 CEACAM20

5.08e-03492093EFO_0021897
Diseaseasthma (is_implicated_in)

NOS1 VDR CYSLTR2 TLR9 IL5

5.31e-031572095DOID:2841 (is_implicated_in)
DiseaseParkinson's disease (implicated_via_orthology)

VPS13C PAK6 FDXR VPS13A PRKN

5.31e-031572095DOID:14330 (implicated_via_orthology)
Diseasediabetic retinopathy (is_implicated_in)

EPO VDR APOB

5.37e-03502093DOID:8947 (is_implicated_in)
DiseaseHyperlipoproteinemia Type IIa

ABCA1 APOB

5.61e-03162092C0745103
Diseasefocal segmental glomerulosclerosis

SCNN1G DNAH6

5.61e-03162092EFO_0004236
DiseaseCannabis use

NCAM1 SDK1

5.61e-03162092EFO_0007585
DiseaseUremia

EPO VDR

6.33e-03172092C0041948
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR9 TJP1

6.33e-03172092DOID:8677 (biomarker_via_orthology)
DiseaseFetal Alcohol Syndrome

ERCC6L NOS1

6.33e-03172092C0015923

Protein segments in the cluster

PeptideGeneStartEntry
RVSDVTKAGHSLELI

VDR

296

P11473
KSAVSGAIRLHISVE

UNC13A

791

Q9UPW8
TVLKLLVAGEGHTRT

GPT

166

P24298
ATHLIAARAGTEKVL

CTDP1

681

Q9Y5B0
VGTTHISKLTDDQLI

ERLEC1

321

Q96DZ1
RHVLGILDRSSKSQS

AKAP9

1751

Q99996
ATKLHISLSLERLSV

BPIFB3

391

P59826
VAELKGHTSRVLSLT

CDC20

436

Q12834
KLVISHLQSGSESLL

ANAPC4

346

Q9UJX5
REKTSDISTLGHLVI

BIRC6

891

Q9NR09
LSAHKLVFIGDTLTR

NEDD9

751

Q14511
ILSAHKLVFIGDTLS

BCAR1

786

P56945
LRAITSTLADVKHTF

ADGRG4

1961

Q8IZF6
DKLLSTALHVAVRTG

ANKRD1

216

Q15327
SKGRTTIVVAHRLST

ABCB5

571

Q2M3G0
HLERTDITKAALGVL

FDXR

201

P22570
ATHLSSLGTLKVRVL

CEACAM20

236

Q6UY09
AQKEHSILLSISSLG

C20orf204

91

A0A1B0GTL2
EATKTLLHSLGTLAQ

ABCA1

256

O95477
LAATVTITHLLKAGD

CTH

91

P32929
VTKIVITDTGRLHSE

CNTNAP4

761

Q9C0A0
SAVKSLVLGRILEHS

CNTNAP4

1136

Q9C0A0
RGSSLTFLTQISKHI

ABCA13

981

Q86UQ4
TLLHGITISNITKED

ABCA13

1776

Q86UQ4
TLAIVLKTSGIFAHS

ABCA13

3631

Q86UQ4
RSLGVHCSKVRSLTL

ACAP3

446

Q96P50
ALKSALSGHLETVIL

ANXA2

86

P07355
HGSKVLTISTLRLTI

BPTF

896

Q12830
ALKSALSGHLETVIL

ANXA2P2

86

A6NMY6
LLRRTHTITIESEGK

CHD7

1491

Q9P2D1
IAHELGRSVTDVTTK

DNAJC1

356

Q96KC8
LGSLVRGITALTSKH

AP4E1

36

Q9UPM8
ITTSVSAGNLILKTH

RC3H2

1156

Q9HBD1
HLLRLTSSLTTKGAS

UQCRC2

81

P22695
SKDLSLLSHGGRVIV

CRYZ

231

Q08257
ATLGTAFLTETKLIH

RFT1

511

Q96AA3
SEGITSLHRKVEIIT

FMN1

1151

Q68DA7
RIHVSGSTIAILKRT

GUCY2C

961

P25092
LVHVITRVLLSGSDK

IPPK

261

Q9H8X2
FRKVLGDIHTTLLSA

GDAP1L1

311

Q96MZ0
ADIVTTTTHKTLRGA

SHMT2

271

P34897
ASEVDSLGVILKVTH

KCTD19

751

Q17RG1
AKGISIQTLRHLESL

DZIP1L

476

Q8IYY4
TFVLSHRARSGLKIS

MEIOB

406

Q8N635
LKRTALHGESNSVLI

ORC4

51

O43929
LLSHVALAVASKLTS

RAB3GAP2

326

Q9H2M9
GIHSSAISVVKILRV

CACNA1F

956

O60840
KLSIRATDSLTGAHA

FAT1

2251

Q14517
AVLHKLTTGATETSR

MUC16

6676

Q8WXI7
GTLFLHKIVLGIETS

OSGEPL1

31

Q9H4B0
RKISRHSVLGAAVSV

DNAJC11

341

Q9NVH1
HKIRELTSSRIGLLT

MCM6

121

Q14566
HILATILSKASSSGR

OR10AD1

221

Q8NGE0
GVIHRDIKSDSILLT

PAK6

521

Q9NQU5
HVVLLLSRSKSTRGE

DIO2

36

Q92813
LCLKVGISSRHLTAI

KIAA0100

206

Q14667
GTTLTSLELKENVHL

LHCGR

196

P22888
HTVLITSRGAQILTK

METAP1D

316

Q6UB28
LIIDNKRSISHLSSG

KIAA0895

81

Q8NCT3
AKTVVSHSLTTLGLE

TMPO

461

P42166
KTHTAAIDERGRLLT

NEK9

606

Q8TD19
VVGGLSHSSISRLKE

RASGRP2

246

Q7LDG7
IKIEISTETITLSHG

ITIH2

771

P19823
KHTLSISRALLSDVV

MFSD9

146

Q8NBP5
RTFHLTRTLTVKVVG

IL1RAP

221

Q9NPH3
TAATLATHELRAVKG

LRRC47

371

Q8N1G4
ETLGLIHTATKGLIR

MFI

201

Q8NCR3
HISFTTSKIGSLIDV

MAGOH

96

P61326
TTGILRHIAAEEVSK

MCM3AP

1126

O60318
VLEQVLHTLSKSGSL

CARMIL3

231

Q8ND23
LHTLSKSGSLEELVL

CARMIL3

236

Q8ND23
LGTERTTLEGHLAKV

KIFC1

181

Q9BW19
HSLKEIISSASVVGL

CAND1

911

Q86VP6
ESSLHLRVVGTEKTS

PCNX2

391

A6NKB5
GLKTLEHVAVTVSIT

PCSK7

521

Q16549
SDTGISLLKVAVHEI

MMP21

271

Q8N119
SILTHDVIRKTGIAV

OR51H1

136

Q8NH63
HSVVSEFILLGLSKS

OR4K13

6

Q8NH42
AGILSTARHLTIEQK

PDPR

86

Q8NCN5
TKVTLGRLHFSETTA

MYRFL

336

Q96LU7
TTGKLHVSLTRLTDG

PNPLA1

116

Q8N8W4
TSTKDLVISLSGILH

KNTC1

1506

P50748
SRLKALGTLVSHVTL

GCN1

911

Q92616
DTLLKEGFHLVSTRT

KCNRG

216

Q8N5I3
AIRAIETLSGKVELH

IGF2BP2

51

Q9Y6M1
EKRLSRGISHASSAI

OTUD7A

111

Q8TE49
KTILISAHGNSSRAL

BPGM

181

P07738
VLDAGHSVSTLEKTL

LAMA5

2676

O15230
IVTSILHIKSTQGRS

OR8B3

221

Q8NGG8
SGSARVKLGHTDILV

EXOSC7

46

Q15024
TDLSLKHISRGLTGL

FBXL14

216

Q8N1E6
KVREHVLGSLSAVTT

PKD1L2

926

Q7Z442
VLTDTLHLKSTLETG

NOS1

316

P29475
HVLTLRQLALKDSGT

OBSCN

3061

Q5VST9
LGAHVTITDRKVALE

METTL21A

86

Q8WXB1
DAAKTLLSLHGSIIV

NID2

1131

Q14112
ALITTAVSADLGTHK

SLC37A2

406

Q8TED4
HQSLAALSKVIRGTT

DYNC2H1

4091

Q8NCM8
EHTGLTLREVSSKLR

APOB

4091

P04114
LIHTSLETLNKAIAG

DNAH6

3911

Q9C0G6
RTKEITVHSGSTVEL

IGSF10

1751

Q6WRI0
TSALVKETLALLSTH

IL5

26

P05113
SVSRSSIDFLLTHKG

AWAT2

161

Q6E213
TELTEATGKLIRTSH

CARD6

876

Q9BX69
HLRISSKGLLSNVID

CCDC138

541

Q96M89
HRLALSLGVDIISSV

CCDC141

841

Q6ZP82
ARISVKGIRHDITTA

CPZ

521

Q66K79
KIHLSATRLVRVSTS

CENPL

296

Q8N0S6
ETHLQTTSGRSIEIK

C5orf24

61

Q7Z6I8
TADVSHTNLGTIRKV

AVL9

266

Q8NBF6
AVLGETTGHRTLKVL

COQ4

71

Q9Y3A0
ALARSSLHGISQVVK

FAM131A

101

Q6UXB0
HVDKAVSGLRSLTTL

EPO

121

P01588
VSRHALLESSLKATR

AREL1

466

O15033
VTKIGVTVLSRIHAR

CBR1

196

P16152
LGSLLSAHRIITDSK

EDEM1

231

Q92611
GIRSHSLKAFETLII

LYST

811

Q99698
KLLVHSSLVGSILSA

MS4A6A

111

Q9H2W1
KRLTLHTAQALGVSS

MAN2A2

936

P49641
VQAIETHLIRKSSSG

MAN1A1

441

P33908
LTHGIRSKISVLANT

EFHB

321

Q8N7U6
LKGVTDHTQRLSIIT

DYNC1H1

3846

Q14204
TQLTITTKVHSLLEG

KCTD6

141

Q8NC69
LEKISRALGILTSHQ

FBXL5

401

Q9UKA1
SHLAKSGTSVILLDR

SDR42E2

51

A6NKP2
TERLENGLLKLHSTS

DNAH9

3066

Q9NYC9
STLHFRSLGSAISKI

CCDC158

211

Q5M9N0
HRILGITSVTAITVL

COX15

326

Q7KZN9
VVVKEESLHSILAGS

HIRA

806

P54198
TSVAARGLDVKHLIL

DDX46

676

Q7L014
IIGSVITSATSVIHK

FDXACB1

466

Q9BRP7
ISAHIDSGKTTLTER

GFM1

51

Q96RP9
AVVNSHSLSLLGKLT

SLC22A15

396

Q8IZD6
GHLSFTEILDTSLKV

SDK1

976

Q7Z5N4
LVSSTGAKVIIHRQD

SCNN1G

321

P51170
VKTLRTILSSVTHNG

RYR1

4821

P21817
FKTLRIDGTVTHLLE

ERCC6L

501

Q2NKX8
TRTLHLLTLNLSEKG

FEZ2

111

Q9UHY8
SDIHSAVLSTIRKLE

PHKA2

576

P46019
GVTSLSKELQRHVTV

LIPT2

191

A6NK58
IAAKSLGHTLVTVSV

NUP210L

621

Q5VU65
IVTSILHIKSTQGRS

OR8B2

221

Q96RD0
KTSTLKHLLGETRSD

PRAC1

26

Q96KF2
HLASILSLKEASTIA

REG4

66

Q9BYZ8
TTAGHLALLVTKNVS

SLC12A5

821

Q9H2X9
LRLASAGKHRSEISV

OR10P1

186

Q8NGE3
IISSILKIHSSEGRS

OR13C9

221

Q8NGT0
VFLDSHLGKTSLTVV

SZT2

3376

Q5T011
SIIKGAEFHVSLLSI

UTP6

231

Q9NYH9
TLHRSISTKVLLAEG

RNF207

401

Q6ZRF8
ALSHLSTTVKRELAG

RAPGEF4

356

Q8WZA2
VKFTLHTRDLLSTVL

TCAIM

111

Q8N3R3
KTTSHTELVRGARIT

SEZ6L

756

Q9BYH1
KSGELISLREEVTHL

SPAG5

1061

Q96R06
GHTLTSRILFKDVVA

PLCD4

351

Q9BRC7
SVGLAVILHTDSRKD

PRKN

116

O60260
HLGKVELASVTLAVA

SLC47A2

61

Q86VL8
ETELLRQTHSSKISG

SPATA22

171

Q8NHS9
VTGEVTNLRSKVSHL

TOGARAM2

536

Q6ZUX3
RVLETLASSLHTLKF

LRRC41

186

Q15345
SVQLLKSTDVGRHSL

AATK

111

Q6ZMQ8
IDGKSHLILSSRSQV

LGI2

381

Q8N0V4
KVDSTLIGSSSHVER

NBPF9

506

P0DPF3
LQKSDGLSTHRSSLL

RFX3

166

P48380
VLSVLASLGASVHKI

ADSL

251

P30566
LVKLLSSLVSSHLEG

PKD1L3

1036

Q7Z443
AEITRLLLEGISSTH

SH3GLB1

206

Q9Y371
ATLIGKVSSHLVLRS

TANC1

686

Q9C0D5
GASTIRLLTSLRAKH

CCT3

456

P49368
LLSIDFDHITRTGKI

TENM1

1796

Q9UKZ4
ELSRLISAHSSLSKG

MYCBP2

3521

O75592
LKSSRHLILTVKDVG

WHRN

346

Q9P202
AVTHAKILGSETLAT

KIAA0753

751

Q2KHM9
ISSTLIALADKHATL

MTA1

51

Q13330
LHSVTTKLVGRVDKL

OLFML2B

166

Q68BL8
KHTFSLRLTSGAEIL

SPTBN5

3606

Q9NRC6
RTLITLLAHSSLTVV

CIP2A

191

Q8TCG1
TSHKGILLETELALT

CMTM5

31

Q96DZ9
SGLRVSHRKALTTII

CYSLTR2

236

Q9NS75
VLFELSKTVLRHSGS

ATP11A

726

P98196
SKTVLRHSGSLTRDN

ATP11A

731

P98196
VRSHARVSSLTLKSI

NCAM1

371

P13591
DRSSELIHSGELTKI

SPATA13

451

Q96N96
TNVTLSSIKETRGLH

TBC1D14

201

Q9P2M4
GDVKRTIHNLLSSTS

XIRP2

1536

A4UGR9
ASILSSILDTIFHKV

XCR1

156

P46094
AVEALIHASTKLSRA

UNC45B

441

Q8IWX7
IHASTKLSRATFIIT

UNC45B

446

Q8IWX7
THGRILKNVSELIIS

ZNF567

136

Q8N184
GKLLSLRVHITSRES

STIL

166

Q15468
TSTRLISGHRSKVNE

WDR90

1426

Q96KV7
RHTGESLTTKLNVTR

ZNF616

766

Q08AN1
LHLSVSLSSGREEAK

VPS13A

2776

Q96RL7
GKVCSRVSSLTLHLR

ZNF260

61

Q3ZCT1
TVTLKQALLGHTDTV

WDFY3

3116

Q8IZQ1
LKGDLRIQHTVTASV

VWF

476

P04275
LVSIRRQSKGHLTDS

TDRP

166

Q86YL5
GTIHSIALTSLTIKL

OR4E1

156

P0C645
SHLSRLEGLVLKDSS

TLR9

281

Q9NR96
ITIKDVVHITFLRGS

STKLD1

286

Q8NE28
HRSVSGLKQTLLAES

TMC4

271

Q7Z404
SHLSKIETRIDTAGL

SPAG1

186

Q07617
TEKVAAIHRLGIGTT

SMOX

351

Q9NWM0
TIIARTKGLSILTHD

TLNRD1

81

Q9H1K6
TGLTHIIETRKVLDL

VPS13C

676

Q709C8
GTILKALSTASRSLH

SEMA5B

496

Q9P283
IKLSDVFGSVRTHGI

GTF3C4

466

Q9UKN8
TDQRSSGIIRLHTIK

TJP1

681

Q07157
TRLSTHLGKAVGVTI

TMEM65

201

Q6PI78
LLVSESRKADGVHTV

TMED1

81

Q13445
GKVISAVSRLSLHSI

VAV2

106

P52735
VRQLKVVASSTGHLA

WNK2

2001

Q9Y3S1
TGLGIISVISHLTKR

TMIGD3

221

P0DMS9
LSTRTNHIETLGKLR

GTF3C1

266

Q12789
TVLDVLEGRTHTISL

VWA8

1251

A3KMH1
GEISDIHTKLLRLSS

TBK1

496

Q9UHD2
IHTKLLRLSSSQGTI

TBK1

501

Q9UHD2
DARTTALLLSVSHLV

TMEM98

156

Q9Y2Y6
LSGIRKVITESTVHL

TRIM16L

91

Q309B1
LLSVEGSTLREALTH

MYO1C

341

O00159
GLTDNIHLVKSSLST

MXRA5

1036

Q9NR99
NKHSVSGTDLLSSRI

MYO3B

1211

Q8WXR4
NSTSSKLLERAHGIL

MYO9A

826

B2RTY4
DHSALLKLGTSVSER

PPP1R9B

106

Q96SB3
SVVSSTKSRLALQHG

NMNAT2

266

Q9BZQ4