Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT TSHZ2 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 KLF18 LHX8 ZNF317 SKI ZNF471 ZBTB18 ZNF354C ZNF786 ZNF404	1.15e-10	1412	80	25	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 KLF18 LHX8 ZNF317 SKI ZNF471 ZNF354C ZNF786 ZNF404	3.78e-08	1459	80	22	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF136 ZNF600 ZFAT ZNF257 ZNF175 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 KLF18 ZNF317 SKI ZNF471 ZNF354C ZNF786	6.91e-06	1244	80	17	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF136 ZNF600 ZFAT ZNF257 ZNF175 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 KLF18 ZNF317 SKI ZNF471 ZNF354C ZNF786	9.17e-06	1271	80	17	GO:0000987
GeneOntologyMolecularFunction	platelet-derived growth factor receptor activity	PDGFRA PDGFRB	4.74e-05	3	80	2	GO:0005017
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK2 GRK3	9.46e-05	4	80	2	GO:0047696
GeneOntologyMolecularFunction	vascular endothelial growth factor binding	PDGFRA PDGFRB	2.35e-04	6	80	2	GO:0038085
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A5	2.35e-04	6	80	2	GO:0008510
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK2 GRK3	3.29e-04	7	80	2	GO:0004703
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	DAB2IP PDGFRA PDGFRB	6.81e-04	43	80	3	GO:0043548
GeneOntologyMolecularFunction	platelet-derived growth factor binding	PDGFRA PDGFRB	1.02e-03	12	80	2	GO:0048407
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A7 SLC4A5	1.20e-03	13	80	2	GO:0140410
GeneOntologyMolecularFunction	platelet-derived growth factor receptor binding	PDGFRA PDGFRB	2.07e-03	17	80	2	GO:0005161
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB HYKK CLK4 PRKDC	2.09e-03	709	80	9	GO:0016773
GeneOntologyMolecularFunction	transcription corepressor activity	CASP8AP2 LIMD1 ZNF451 SKI ZNF653	2.27e-03	229	80	5	GO:0003714
GeneOntologyMolecularFunction	protein kinase activity	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB CLK4 PRKDC	2.75e-03	600	80	8	GO:0004672
GeneOntologyMolecularFunction	SUMO ligase activity	ZNF451 ZMIZ1	2.87e-03	20	80	2	GO:0061665
GeneOntologyBiologicalProcess	regulation of fibroblast proliferation	DAB2IP GRK2 PDGFRA PDGFRB PRKDC ZMIZ1 SKI	9.39e-07	135	80	7	GO:0048145
GeneOntologyBiologicalProcess	fibroblast proliferation	DAB2IP GRK2 PDGFRA PDGFRB PRKDC ZMIZ1 SKI	2.93e-06	160	80	7	GO:0048144
GeneOntologyBiologicalProcess	positive regulation of fibroblast proliferation	GRK2 PDGFRA PDGFRB PRKDC ZMIZ1	1.99e-05	85	80	5	GO:0048146
GeneOntologyBiologicalProcess	metanephric glomerulus morphogenesis	PDGFRA PDGFRB	4.45e-05	3	80	2	GO:0072275
GeneOntologyBiologicalProcess	metanephric glomerular capillary formation	PDGFRA PDGFRB	4.45e-05	3	80	2	GO:0072277
GeneOntologyBiologicalProcess	metanephric glomerulus vasculature morphogenesis	PDGFRA PDGFRB	4.45e-05	3	80	2	GO:0072276
GeneOntologyBiologicalProcess	VEGF-activated platelet-derived growth factor receptor signaling pathway	PDGFRA PDGFRB	4.45e-05	3	80	2	GO:0038086
GeneOntologyBiologicalProcess	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	PDGFRA PDGFRB	4.45e-05	3	80	2	GO:0038091
GeneOntologyBiologicalProcess	retina development in camera-type eye	SLC4A7 ALMS1 PDGFRA PDGFRB SKI SLC4A5	1.71e-04	211	80	6	GO:0060041
GeneOntologyBiologicalProcess	retina vasculature development in camera-type eye	SLC4A7 PDGFRA PDGFRB	2.12e-04	30	80	3	GO:0061298
GeneOntologyBiologicalProcess	glomerulus vasculature morphogenesis	PDGFRA PDGFRB	2.21e-04	6	80	2	GO:0072103
GeneOntologyBiologicalProcess	glomerular capillary formation	PDGFRA PDGFRB	2.21e-04	6	80	2	GO:0072104
GeneOntologyBiologicalProcess	positive regulation of smooth muscle cell migration	DOCK4 MYO5A PDGFRB DOCK7	3.06e-04	83	80	4	GO:0014911
GeneOntologyBiologicalProcess	renal system vasculature morphogenesis	PDGFRA PDGFRB	3.08e-04	7	80	2	GO:0061438
GeneOntologyBiologicalProcess	kidney vasculature morphogenesis	PDGFRA PDGFRB	3.08e-04	7	80	2	GO:0061439
GeneOntologyBiologicalProcess	negative regulation of muscle contraction	DOCK4 GRK2 IRAG1	3.36e-04	35	80	3	GO:0045932
GeneOntologyBiologicalProcess	positive regulation of vascular associated smooth muscle cell migration	DOCK4 MYO5A DOCK7	3.66e-04	36	80	3	GO:1904754
GeneOntologyBiologicalProcess	metanephric glomerulus vasculature development	PDGFRA PDGFRB	4.10e-04	8	80	2	GO:0072239
GeneOntologyBiologicalProcess	lung growth	PDGFRA PDGFRB	4.10e-04	8	80	2	GO:0060437
Domain	zf-C2H2	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	3.01e-17	693	78	25	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	4.09e-16	775	78	25	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	4.35e-16	777	78	25	PS00028
Domain	Znf_C2H2-like	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	7.60e-16	796	78	25	IPR015880
Domain	Znf_C2H2	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	9.86e-16	805	78	25	IPR007087
Domain	ZnF_C2H2	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	1.07e-15	808	78	25	SM00355
Domain	Znf_C2H2/integrase_DNA-bd	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 ZNF781 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	4.54e-15	694	78	23	IPR013087
Domain	-	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 ZNF781 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	3.21e-14	679	78	22	3.30.160.60
Domain	KRAB	ZNF133 ZNF136 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 ZNF485 ZNF431 ZNF317 ZNF471 ZNF354C ZNF786 ZNF404	2.37e-10	358	78	14	PS50805
Domain	KRAB	ZNF133 ZNF136 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 ZNF485 ZNF431 ZNF317 ZNF471 ZNF354C ZNF786 ZNF404	2.37e-10	358	78	14	PF01352
Domain	KRAB	ZNF133 ZNF136 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 ZNF485 ZNF431 ZNF317 ZNF471 ZNF354C ZNF786 ZNF404	3.52e-10	369	78	14	SM00349
Domain	KRAB	ZNF133 ZNF136 ZNF257 ZNF175 ZNF566 ZFP1 ZNF813 ZNF485 ZNF431 ZNF317 ZNF471 ZNF354C ZNF786 ZNF404	3.65e-10	370	78	14	IPR001909
Domain	zf-C2H2_6	ZNF133 ZNF136 ZNF600 ZNF566 ZNF813 ZNF431 ZNF770 ZNF317 ZNF354C ZNF404	7.16e-07	314	78	10	PF13912
Domain	Ribosomal_L26	RPL26 RPL26L1	1.72e-05	2	78	2	PF16906
Domain	Ribosomal_L26/L24P_euk/arc	RPL26 RPL26L1	1.72e-05	2	78	2	IPR005756
Domain	Ribosomal_L24/26_CS	RPL26 RPL26L1	5.15e-05	3	78	2	IPR005825
Domain	RIBOSOMAL_L24	RPL26 RPL26L1	5.15e-05	3	78	2	PS01108
Domain	Tyr_kinase_CSF1/PDGF_rcpt	PDGFRA PDGFRB	2.55e-04	6	78	2	IPR016243
Domain	GPCR_kinase	GRK2 GRK3	3.57e-04	7	78	2	IPR000239
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A5	3.57e-04	7	78	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A5	3.57e-04	7	78	2	PS00219
Domain	KOW	RPL26 RPL26L1	3.57e-04	7	78	2	SM00739
Domain	Kinase-like_dom	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB HYKK CLK4 PRKDC	4.20e-04	542	78	9	IPR011009
Domain	Tyr_kinase_rcpt_3_CS	PDGFRA PDGFRB	4.74e-04	8	78	2	IPR001824
Domain	RECEPTOR_TYR_KIN_III	PDGFRA PDGFRB	4.74e-04	8	78	2	PS00240
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A5	6.08e-04	9	78	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A5	6.08e-04	9	78	2	PF07565
Domain	-	SLC4A7 SLC4A5	6.08e-04	9	78	2	3.40.1100.10
Domain	HCO3_cotransp	SLC4A7 SLC4A5	7.58e-04	10	78	2	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A5	7.58e-04	10	78	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A5	7.58e-04	10	78	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A5	7.58e-04	10	78	2	IPR003020
Domain	KOW	RPL26 RPL26L1	9.24e-04	11	78	2	IPR005824
Domain	KOW	RPL26 RPL26L1	9.24e-04	11	78	2	PF00467
Domain	DOCK_C	DOCK4 DOCK7	9.24e-04	11	78	2	IPR010703
Domain	DHR-1_domain	DOCK4 DOCK7	9.24e-04	11	78	2	IPR027007
Domain	DHR_2	DOCK4 DOCK7	9.24e-04	11	78	2	PS51651
Domain	DHR_1	DOCK4 DOCK7	9.24e-04	11	78	2	PS51650
Domain	DOCK-C2	DOCK4 DOCK7	9.24e-04	11	78	2	PF14429
Domain	DHR-2	DOCK4 DOCK7	9.24e-04	11	78	2	IPR027357
Domain	DHR-2	DOCK4 DOCK7	9.24e-04	11	78	2	PF06920
Domain	DOCK	DOCK4 DOCK7	9.24e-04	11	78	2	IPR026791
Domain	Protein_kinase_ATP_BS	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB CLK4	1.03e-03	379	78	7	IPR017441
Domain	AGC-kinase_C	CDC42BPG GRK2 GRK3	1.66e-03	56	78	3	IPR000961
Domain	AGC_KINASE_CTER	CDC42BPG GRK2 GRK3	1.66e-03	56	78	3	PS51285
Domain	S_TK_X	CDC42BPG GRK2 GRK3	1.66e-03	56	78	3	SM00133
Domain	Translation_prot_SH3-like	RPL26 RPL26L1	2.25e-03	17	78	2	IPR008991
Domain	Rib_L2_dom2	RPL26 RPL26L1	2.52e-03	18	78	2	IPR014722
Domain	-	RPL26 RPL26L1	2.52e-03	18	78	2	2.30.30.30
Domain	PROTEIN_KINASE_ATP	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB CLK4	3.04e-03	459	78	7	PS00107
Domain	S_TKc	CDC42BPG CDK18 GRK2 GRK3 PDGFRA CLK4	3.89e-03	359	78	6	SM00220
Domain	Prot_kinase_dom	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB CLK4	4.31e-03	489	78	7	IPR000719
Domain	PROTEIN_KINASE_DOM	CDC42BPG CDK18 GRK2 GRK3 PDGFRA PDGFRB CLK4	4.50e-03	493	78	7	PS50011
Domain	RGS	GRK2 GRK3	9.37e-03	35	78	2	PF00615
Domain	RGS	GRK2 GRK3	9.37e-03	35	78	2	SM00315
Domain	RGS	GRK2 GRK3	9.90e-03	36	78	2	PS50132
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF133 ZNF136 ZNF600 ZNF775 TJP1 ZNF257 ZNF175 ZNF566 ZFP1 ZNF485 ZNF431 ZNF770 ZNF317 SKI ZNF471 ZNF354C ZNF786	1.24e-05	1387	55	17	M734
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GLIPR1 SART1 GDPD1 ZNF142 SLC4A7 LIMD1 PDGFRB TJP1 ZNF451 ZNF566 ZNF813 DOCK7 ZNF485 FADS2 PRKDC ZNF317 NONO THAP12 SLX4	2.99e-11	1203	81	19	29180619
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF136 ZNF257 ZNF566 ZFP1 ZNF813 ZNF485 ZNF317	2.31e-07	181	81	7	37372979
Pubmed	Human transcription factor protein interaction networks.	RPL26 ALMS1 LIMD1 MYO5A RPL26L1 ZNF451 ZNF485 MRPS5 ZNF770 INO80 ZMIZ1 LHX8 SKI ZNF471 SLX4	9.48e-07	1429	81	15	35140242
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	SART1 RPL26 MYO5A TJP1 RPL26L1 DOCK7 PRKDC NONO	1.02e-06	328	81	8	23398456
Pubmed	Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.	GRK2 GRK3 PDGFRA	1.44e-06	10	81	3	1869533
Pubmed	Death receptors DR6 and TROY regulate brain vascular development.	PDGFRB TJP1 TNFRSF21	1.98e-06	11	81	3	22340501
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SART1 ZNF775 LIMD1 BTBD7 ZNF175 ZNF451 ZNF566 LHX8 ZNF653 ZNF354C ZNF786	2.75e-06	808	81	11	20412781
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	5.36e-06	2	81	2	8638670
Pubmed	Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis.	PDGFRA PDGFRB	5.36e-06	2	81	2	19333949
Pubmed	Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease.	PDGFRA PDGFRB	5.36e-06	2	81	2	17363728
Pubmed	Combined anti-PDGFRalpha and PDGFRbeta targeting in non-small cell lung cancer.	PDGFRA PDGFRB	5.36e-06	2	81	2	19115205
Pubmed	Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas.	PDGFRA PDGFRB	5.36e-06	2	81	2	17145809
Pubmed	The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation.	PDGFRA PDGFRB	5.36e-06	2	81	2	19644140
Pubmed	Platelet-derived growth factor receptor expression and activation in choroid plexus tumors.	PDGFRA PDGFRB	5.36e-06	2	81	2	19717644
Pubmed	An automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers.	PDGFRA PDGFRB	5.36e-06	2	81	2	19843560
Pubmed	Structure, organization, and transcription units of the human alpha-platelet-derived growth factor receptor gene, PDGFRA.	PDGFRA PDGFRB	5.36e-06	2	81	2	8586421
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	5.36e-06	2	81	2	33060647
Pubmed	Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases.	PDGFRA PDGFRB	5.36e-06	2	81	2	32737331
Pubmed	Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease.	PDGFRA PDGFRB	5.36e-06	2	81	2	11544480
Pubmed	A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a heterodimeric receptor complex.	PDGFRA PDGFRB	5.36e-06	2	81	2	7523122
Pubmed	Vascular endothelial growth factor A competitively inhibits platelet-derived growth factor (PDGF)-dependent activation of PDGF receptor and subsequent signaling events and cellular responses.	PDGFRA PDGFRB	5.36e-06	2	81	2	22431518
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	5.36e-06	2	81	2	8035170
Pubmed	An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development.	PDGFRA PDGFRB	5.36e-06	2	81	2	11782318
Pubmed	Human cytomegalovirus downregulates expression of receptors for platelet-derived growth factor by smooth muscle cells.	PDGFRA PDGFRB	5.36e-06	2	81	2	17344284
Pubmed	N-acetylcysteine suppresses retinal detachment in an experimental model of proliferative vitreoretinopathy.	PDGFRA PDGFRB	5.36e-06	2	81	2	20489144
Pubmed	Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.	PDGFRA PDGFRB	5.36e-06	2	81	2	22661233
Pubmed	Ligand-induced interaction between alpha- and beta-type platelet-derived growth factor (PDGF) receptors: role of receptor heterodimers in kinase activation.	PDGFRA PDGFRB	5.36e-06	2	81	2	1847074
Pubmed	Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis.	PDGFRA PDGFRB	5.36e-06	2	81	2	20107158
Pubmed	Platelet-derived growth factor receptor: current views of the two-subunit model.	PDGFRA PDGFRB	5.36e-06	2	81	2	2161888
Pubmed	Roles of platelet-derived growth factor in the developing and mature nervous systems.	PDGFRA PDGFRB	5.36e-06	2	81	2	9233543
Pubmed	Platelet-derived growth factor may be associated with fibrosis in a Down syndrome patient with transient myeloproliferative disorder.	PDGFRA PDGFRB	5.36e-06	2	81	2	18331602
Pubmed	Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor.	GRK2 PDGFRB	5.36e-06	2	81	2	15271984
Pubmed	PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy.	PDGFRA PDGFRB	5.36e-06	2	81	2	18288404
Pubmed	Calcitriol inhibits growth response to Platelet-Derived Growth Factor-BB in human prostate cells.	PDGFRA PDGFRB	5.36e-06	2	81	2	15862965
Pubmed	B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin.	PDGFRA PDGFRB	5.36e-06	2	81	2	22697462
Pubmed	Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy.	PDGFRA PDGFRB	5.36e-06	2	81	2	28129672
Pubmed	Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.	PDGFRA PDGFRB	5.36e-06	2	81	2	14624252
Pubmed	PDGF receptors in tumor biology: prognostic and predictive potential.	PDGFRA PDGFRB	5.36e-06	2	81	2	25145436
Pubmed	Molecular analysis of PDGFRA and PDGFRB genes by rapid single-strand conformation polymorphism (SSCP) in patients with core-binding factor leukaemias with KIT or FLT3 mutation.	PDGFRA PDGFRB	5.36e-06	2	81	2	19035305
Pubmed	Structural determinants in the platelet-derived growth factor alpha-receptor implicated in modulation of chemotaxis.	PDGFRA PDGFRB	5.36e-06	2	81	2	8617789
Pubmed	Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer.	PDGFRA PDGFRB	5.36e-06	2	81	2	7665222
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	5.36e-06	2	81	2	10198406
Pubmed	A new look at platelet-derived growth factor in renal disease.	PDGFRA PDGFRB	5.36e-06	2	81	2	18077793
Pubmed	Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways.	PDGFRA PDGFRB	5.36e-06	2	81	2	2554309
Pubmed	An efficient directional cloning system to construct cDNA libraries containing full-length inserts at high frequency.	PDGFRA PDGFRB	5.36e-06	2	81	2	2531695
Pubmed	Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.	PDGFRA PDGFRB	5.36e-06	2	81	2	27248825
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	5.36e-06	2	81	2	11762794
Pubmed	Pigment epithelium-derived factor 34-mer peptide prevents liver fibrosis and hepatic stellate cell activation through down-regulation of the PDGF receptor.	PDGFRA PDGFRB	5.36e-06	2	81	2	24763086
Pubmed	Platelet-derived growth factor receptor signaling is not involved in osteogenic differentiation of human mesenchymal stem cells.	PDGFRA PDGFRB	5.36e-06	2	81	2	19839721
Pubmed	Expression of platelet-derived growth factor receptor in low-grade endometrial stromal sarcomas in the absence of activating mutations.	PDGFRA PDGFRB	5.36e-06	2	81	2	17448020
Pubmed	Two different subunits associate to create isoform-specific platelet-derived growth factor receptors.	PDGFRA PDGFRB	5.36e-06	2	81	2	2542288
Pubmed	Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast.	PDGFRA PDGFRB	5.36e-06	2	81	2	30485861
Pubmed	Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas.	PDGFRA PDGFRB	5.36e-06	2	81	2	18157090
Pubmed	Reduced expression of PDGF and PDGF receptors during impaired wound healing.	PDGFRA PDGFRB	5.36e-06	2	81	2	9242497
Pubmed	Postnatal tendon growth and remodeling require platelet-derived growth factor receptor signaling.	PDGFRA PDGFRB	5.36e-06	2	81	2	29341790
Pubmed	Autocrine PDGFR signaling promotes mammary cancer metastasis.	PDGFRA PDGFRB	5.36e-06	2	81	2	16741576
Pubmed	Development of hygromas or severe edema during treatment with the tyrosine kinase inhibitor STI571 is not associated with platelet-derived growth factor receptor (PDGFR) gene polymorphisms.	PDGFRA PDGFRB	5.36e-06	2	81	2	15380338
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	AMZ1 ZNF431 GRIN3A SLX4	6.28e-06	51	81	4	11853319
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF133 ZNF136 ZNF142	8.08e-06	17	81	3	7557990
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	1.60e-05	3	81	2	10754297
Pubmed	Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor.	PDGFRA PDGFRB	1.60e-05	3	81	2	27881889
Pubmed	Expression of tyrosine kinase receptors in malignant midgut carcinoid tumors.	PDGFRA PDGFRB	1.60e-05	3	81	2	17047316
Pubmed	SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.	PDGFRA PDGFRB	1.60e-05	3	81	2	35508129
Pubmed	Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.	GRK2 GRK3	1.60e-05	3	81	2	10085131
Pubmed	Cell migration is regulated by platelet-derived growth factor receptor endocytosis.	DOCK4 PDGFRB	1.60e-05	3	81	2	19528233
Pubmed	Embryonic mouse testis development: role of platelet derived growth factor (PDGF-BB).	PDGFRA PDGFRB	1.60e-05	3	81	2	15254974
Pubmed	Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease.	PDGFRA PDGFRB	1.60e-05	3	81	2	22940072
Pubmed	Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.	GRK2 GRK3	1.60e-05	3	81	2	7761854
Pubmed	Coexpression of PDGFR-alpha, PDGFR-beta and VEGF as a prognostic factor in patients with hepatocellular carcinoma.	PDGFRA PDGFRB	1.60e-05	3	81	2	21574155
Pubmed	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.	GRK2 GRK3	1.60e-05	3	81	2	31604529
Pubmed	PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytes.	PDGFRA PDGFRB	1.60e-05	3	81	2	29158445
Pubmed	PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome.	PDGFRA PDGFRB	1.60e-05	3	81	2	23146028
Pubmed	The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence.	PDGFRA PDGFRB	1.60e-05	3	81	2	29380207
Pubmed	Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	GRK2 GRK3	1.60e-05	3	81	2	12130708
Pubmed	Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas.	PDGFRA PDGFRB	1.60e-05	3	81	2	18519768
Pubmed	Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarcomas.	PDGFRA PDGFRB	1.60e-05	3	81	2	17298867
Pubmed	Conservation in sequence and affinity of human and rodent PDGF ligands and receptors.	PDGFRA PDGFRB	1.60e-05	3	81	2	8318539
Pubmed	Clinically relevant biomarkers to select patients for targeted inhibitor therapy after resection of hepatocellular carcinoma.	PDGFRA PDGFRB	1.60e-05	3	81	2	21590454
Pubmed	Identification of novel FLT3 kinase inhibitors.	PDGFRA PDGFRB	1.60e-05	3	81	2	23567961
Pubmed	Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity.	PDGFRA PDGFRB	1.60e-05	3	81	2	11046132
Pubmed	Dysregulation of Amphiregulin stimulates the pathogenesis of cystic lymphangioma.	PDGFRA PDGFRB	1.60e-05	3	81	2	33941693
Pubmed	Pdgfra and Pdgfrb genetically interact during craniofacial development.	PDGFRA PDGFRB	1.60e-05	3	81	2	26971580
Pubmed	PDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance.	PDGFRA PDGFRB	1.60e-05	3	81	2	25502837
Pubmed	Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain.	PDGFRA PDGFRB	1.60e-05	3	81	2	10347229
Pubmed	Expression of c-kit and platelet-derived growth factor receptors in ovarian granulosa cell tumors.	PDGFRA PDGFRB	1.60e-05	3	81	2	18492696
Pubmed	Mesenchymal stromal cells: inhibiting PDGF receptors or depleting fibronectin induces mesodermal progenitors with endothelial potential.	PDGFRA PDGFRB	1.60e-05	3	81	2	24022915
Pubmed	PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke.	PDGFRA PDGFRB	1.60e-05	3	81	2	26435273
Pubmed	Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers.	PDGFRA PDGFRB	1.60e-05	3	81	2	15791568
Pubmed	Platelet-derived growth factor (PDGF) receptors in the developing mouse optic pathway.	PDGFRA PDGFRB	1.60e-05	3	81	2	8011581
Pubmed	Pericyte loss and microaneurysm formation in PDGF-B-deficient mice.	PDGFRA PDGFRB	1.60e-05	3	81	2	9211853
Pubmed	Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.	GRK2 PDGFRB	1.60e-05	3	81	2	12381737
Pubmed	Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.	PDGFRA PDGFRB	1.60e-05	3	81	2	16971512
Pubmed	Expression and molecular analysis of c-kit and PDGFRs in Kaposi's sarcoma of different stages and epidemiological settings.	PDGFRA PDGFRB	1.60e-05	3	81	2	19302534
Pubmed	Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation.	PDGFRA PDGFRB	1.60e-05	3	81	2	10733900
Pubmed	Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling.	PDGFRA PDGFRB	1.60e-05	3	81	2	21310211
Pubmed	A novel function of p53: a gatekeeper of retinal detachment.	PDGFRA PDGFRB	1.60e-05	3	81	2	22901751
Pubmed	Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.	PDGFRA PDGFRB	1.60e-05	3	81	2	18184658
Pubmed	Primary Cilia and Coordination of Receptor Tyrosine Kinase (RTK) and Transforming Growth Factor β (TGF-β) Signaling.	PDGFRA PDGFRB	1.60e-05	3	81	2	27638178
Pubmed	Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.	TENM4 ZMIZ1 SLC45A1 MUCL3	1.66e-05	65	81	4	23453885
Pubmed	Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.	PDGFRA PDGFRB TJP1	2.38e-05	24	81	3	20371769
Interaction	RNF4 interactions	GLIPR1 SART1 GDPD1 ZNF142 SLC4A7 LIMD1 PDGFRB TJP1 ZNF451 ZNF566 ZNF813 DOCK7 ZNF485 FADS2 PRKDC ZNF317 NONO THAP12 SLX4	1.58e-06	1412	79	19	int:RNF4
Interaction	ZNF467 interactions	RPL26L1 ZNF451 ZNF813 MRPS5 ZNF770 ZNF317 THAP12	6.56e-06	179	79	7	int:ZNF467
Interaction	CACNG5 interactions	ZNF142 ZNF775 ZNF770 THAP12	1.98e-05	41	79	4	int:CACNG5
Interaction	BRSK2 interactions	SLC4A7 TENM4 GRK2 TJP1 ATG2B	2.91e-05	91	79	5	int:BRSK2
Interaction	E4F1 interactions	RPL26 RPL26L1 MRPS5 ZNF770 PRKDC	4.81e-05	101	79	5	int:E4F1
Cytoband	11q13.1	SART1 CDC42BPG GRK2	1.95e-04	63	81	3	11q13.1
Cytoband	5q35	CLK4 ZNF354C	7.59e-04	23	81	2	5q35
Cytoband	2p13	ALMS1 SLC4A5	7.59e-04	23	81	2	2p13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF133 ZNF136 ZNF600 ZNF142 ZFAT ZNF775 TSHZ2 ZNF781 ZNF257 ZNF175 ZNF451 ZNF566 ZFP1 ZNF813 KLF14 ZNF485 ZNF431 ZNF770 ZNF317 ZNF471 ZBTB18 ZNF653 ZNF354C ZNF786 ZNF404	3.67e-19	718	63	25	28
GeneFamily	Zinc fingers C2H2-type\|Kruppel like factors	KLF14 KLF18	1.76e-03	18	63	2	624
ToppCell	(5)_Fibroblast-D\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PCSK1 TCEAL7 PDGFRA PDGFRB TSHZ2 PAPPA PTGFR	7.85e-08	199	81	7	3f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 GRK3 LIMD1 PDGFRB IRAG1 TNFRSF21	1.08e-06	184	81	6	9c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	DOCK4 MYO5A PDGFRA TSHZ2 ZFP1 ZNF354C	1.08e-06	184	81	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 GRK3 LIMD1 PDGFRB IRAG1 TNFRSF21	1.08e-06	184	81	6	31dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GLIPR1 PDGFRA PDGFRB TSHZ2 FADS2 IRAG1	1.39e-06	192	81	6	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA IRAG1	1.48e-06	194	81	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLK4 ARFGEF1 ZNF317 ZBTB18 ZNF786	4.48e-06	133	81	5	8ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDK18 PDGFRA TSHZ2 PTGFR TNFRSF21	8.05e-06	150	81	5	909ccab92855f5f049dc29593aadab1ea973297b
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-Treg\|ICU-NoSEP / Disease, Lineage and Cell Type	ZNF133 SLC4A7 TSHZ2 ZNF781 ZNF485	1.07e-05	159	81	5	d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD1 TENM4 AMZ1 TNFRSF21 SLC4A5	1.39e-05	168	81	5	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD1 TENM4 AMZ1 TNFRSF21 SLC4A5	1.39e-05	168	81	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD1 TENM4 AMZ1 TNFRSF21 SLC4A5	1.43e-05	169	81	5	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_F\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CDK18 ZNF775 PDGFRB KLF14 PCDHAC1	1.47e-05	170	81	5	71718dcebd48105994c313bb55babc70301170a0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 SLC4A7 LIMD1 PDGFRB IRAG1	1.60e-05	173	81	5	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 SLC4A7 LIMD1 PDGFRB IRAG1	1.60e-05	173	81	5	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	1.89e-05	179	81	5	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 TENM4 PDGFRA PAPPA PTGFR	1.99e-05	181	81	5	47dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 TENM4 PDGFRA PAPPA PTGFR	1.99e-05	181	81	5	19103221c3a5a16b16378348004b2c50caee4f01
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRK3 LIMD1 PDGFRB IRAG1 TNFRSF21	1.99e-05	181	81	5	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRK3 LIMD1 PDGFRB IRAG1 TNFRSF21	1.99e-05	181	81	5	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	2.16e-05	184	81	5	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	ADAMTSL1 PDGFRA PDGFRB TSHZ2 PAPPA	2.21e-05	185	81	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 PDGFRB TSHZ2 PAPPA IRAG1	2.21e-05	185	81	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 ZNF600 LIMD1 ZNF431 MAPKBP1	2.27e-05	186	81	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 ZNF600 LIMD1 ZNF431 MAPKBP1	2.27e-05	186	81	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA PDGFRB PAPPA ZNF471 PTGFR	2.39e-05	188	81	5	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GLIPR1 PDGFRA PDGFRB TSHZ2 FADS2	2.65e-05	192	81	5	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PDGFRA PDGFRB TSHZ2 IRAG1	2.71e-05	193	81	5	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA	2.71e-05	193	81	5	cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA	2.71e-05	193	81	5	6ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA	2.71e-05	193	81	5	e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PDGFRA PDGFRB TSHZ2 IRAG1	2.85e-05	195	81	5	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PDGFRA PDGFRB TSHZ2 IRAG1	2.85e-05	195	81	5	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 GRK3 PDGFRB TSHZ2 IRAG1	2.85e-05	195	81	5	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 GRK3 PDGFRB TSHZ2 IRAG1	2.85e-05	195	81	5	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA	2.99e-05	197	81	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 PDGFRA PDGFRB TSHZ2 PAPPA	2.99e-05	197	81	5	6668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	ZNF133 SLC4A7 TSHZ2 ZNF781 ZNF485	3.07e-05	198	81	5	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	DOCK4 ADAMTSL1 SLC4A7 MYO5A TSHZ2	3.07e-05	198	81	5	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	368C-Fibroblasts-Fibroblast-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB TSHZ2 PAPPA	3.14e-05	199	81	5	5a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TCEAL7 TENM4 PDGFRA PDGFRB PAPPA	3.14e-05	199	81	5	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	368C-Fibroblasts-Fibroblast-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB TSHZ2 PAPPA	3.14e-05	199	81	5	66545eb7f65e450b742628fd431956e13330a0d3
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TCEAL7 TENM4 PDGFRA PDGFRB PAPPA	3.14e-05	199	81	5	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	343B-Fibroblasts-Fibroblast-F\|343B / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB TSHZ2 PAPPA	3.14e-05	199	81	5	b877c1d24357249781032e99d4237f72789cc9b8
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TCEAL7 TENM4 PDGFRA PDGFRB PAPPA	3.14e-05	199	81	5	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	343B-Fibroblasts-Fibroblast-F-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB TSHZ2 PAPPA	3.14e-05	199	81	5	e32fa66f3361474088ba1dd58574822537950d59
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	TCEAL7 ADAMTSL1 PDGFRA PDGFRB TSHZ2	3.22e-05	200	81	5	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	3.22e-05	200	81	5	1a3d29a580d1b405a74869a1da3e818c581fc559
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E---L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	3.22e-05	200	81	5	6f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	3.22e-05	200	81	5	86705dfc05b3e1576543b93883c88fb55b742855
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK1 GLIPR1 THEMIS TENM4 TSHZ2	3.22e-05	200	81	5	db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS SLC4A7 FADS2 ZNF786	1.24e-04	140	81	4	7b359bfbd404ab06d799048252f4985d85852048
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP47 BTBD7 NONO ZNF786	1.35e-04	143	81	4	cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRA PDGFRB GRIN3A IRAG1	1.62e-04	150	81	4	8645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell	droplet-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL26 GRK3 AMZ1 TNFRSF21	1.66e-04	151	81	4	c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCell	367C-Fibroblasts-Fibroblast-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB PTGFR	1.79e-04	154	81	4	dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell	367C-Fibroblasts-Fibroblast-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	TCEAL7 PDGFRA PDGFRB PTGFR	1.79e-04	154	81	4	4bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 GRK3 AMZ1 TNFRSF21	1.93e-04	157	81	4	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 RPL26 GRK3 MYO5A	1.97e-04	158	81	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB GRIN3A IRAG1 MUCL3	2.02e-04	159	81	4	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDPD1 LIMD1 SLC45A1 ZNF404	2.17e-04	162	81	4	ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 GRK3 AMZ1 TNFRSF21	2.22e-04	163	81	4	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 GRK3 AMZ1 TNFRSF21	2.22e-04	163	81	4	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB APOL5 GRIN3A IRAG1	2.28e-04	164	81	4	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP GRK3 SLC45A1 SLC4A5	2.28e-04	164	81	4	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP GRK3 SLC45A1 SLC4A5	2.28e-04	164	81	4	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP GRK3 SLC45A1 SLC4A5	2.28e-04	164	81	4	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	CV-Mild-3\|Mild / Virus stimulation, Condition and Cluster	ZNF133 ZNF775 TSHZ2 ZNF431	2.38e-04	166	81	4	5599f90fc0e15a3670b03187085eba91228390a2
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	CDK18 ZFAT ALMS1 ZMIZ1	2.49e-04	168	81	4	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ZFAT TENM4 ZNF471 TNFRSF21	2.49e-04	168	81	4	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASP8AP2 GRK3 AMZ1 ZNF354C	2.49e-04	168	81	4	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIPR1 THEMIS TENM4 TSHZ2	2.79e-04	173	81	4	ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCEAL7 PDGFRA TSHZ2 TNFRSF21	2.85e-04	174	81	4	9d22a554617a93701d0945de63cc3e7b24322c40
ToppCell	droplet-Lung-nan-21m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 GRK3 AMZ1 TNFRSF21	2.85e-04	174	81	4	763ca53339d9e236da8463f2a9d1bd39d4385d75
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRK3 LIMD1 PDGFRB TNFRSF21	2.85e-04	174	81	4	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP PDGFRB PAPPA IRAG1	2.85e-04	174	81	4	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRK3 LIMD1 PDGFRB TNFRSF21	2.85e-04	174	81	4	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDGFRA PDGFRB PAPPA IRAG1	2.91e-04	175	81	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	Pericytes-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	TCEAL7 ADAMTSL1 PDGFRB IRAG1	2.91e-04	175	81	4	ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRA PDGFRB TSHZ2 IRAG1	2.98e-04	176	81	4	e9152defb4fd41267fb33c42c01fd0c683280783
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRA PDGFRB TSHZ2 IRAG1	2.98e-04	176	81	4	a4d269075aa0efc46fa251b379f334e50c69391d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRA PDGFRB TSHZ2 IRAG1	2.98e-04	176	81	4	cc6f65a7d2c622841c9d1ab3755586039d4ccc4d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDC42BPG ZNF142 GRK3 ZNF653	3.04e-04	177	81	4	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ADAMTSL1 PDGFRB IRAG1	3.04e-04	177	81	4	dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK1 GLIPR1 THEMIS TSHZ2	3.04e-04	177	81	4	7e799333307448c6a94d1f33dbc59c543336f45e
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTSL1 PDGFRA PDGFRB IRAG1	3.11e-04	178	81	4	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 GRK3 FADS2 IRAG1	3.11e-04	178	81	4	742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 TENM4 PAPPA PTGFR	3.11e-04	178	81	4	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ADAMTSL1 PDGFRB IRAG1	3.11e-04	178	81	4	416f85e51f45ec7949451fd47611a84e33e87245
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CDK18 ADAMTSL1 PDGFRB IRAG1	3.17e-04	179	81	4	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK1 GLIPR1 TENM4 TSHZ2	3.17e-04	179	81	4	d3d3a9afaac28fa4f2c448c73d79bcbbbea088d7
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CLK4 ARFGEF1 ZBTB18 ZNF786	3.24e-04	180	81	4	62511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDGFRA TSHZ2 PAPPA IRAG1	3.24e-04	180	81	4	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PDGFRA TSHZ2 IRAG1 TNFRSF21	3.31e-04	181	81	4	7e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 TSHZ2 PAPPA ZNF471	3.31e-04	181	81	4	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDGFRA PDGFRB PAPPA IRAG1	3.31e-04	181	81	4	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 TSHZ2 PAPPA ZNF471	3.31e-04	181	81	4	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	TCEAL7 PDGFRA PDGFRB IRAG1	3.31e-04	181	81	4	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDGFRA PDGFRB PAPPA IRAG1	3.31e-04	181	81	4	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDK18 MYO5A DOCK7 PAPPA	3.31e-04	181	81	4	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
Drug	3-pyridyl)urea	PDGFRA PDGFRB	1.25e-05	2	81	2	CID000202697
Drug	isocurcumenol	PDGFRA PDGFRB	1.25e-05	2	81	2	CID005255901
Drug	4-nitrophenylurea	PDGFRA PDGFRB	1.25e-05	2	81	2	CID000313520
Drug	5,7-Dmpq	PDGFRA PDGFRB	1.25e-05	2	81	2	CID000003139
Drug	tyrphostin AG1296	GRK2 GRK3 PDGFRA PDGFRB	1.81e-05	44	81	4	CID000002049
Drug	LS-64027	PDGFRA PDGFRB	3.74e-05	3	81	2	CID000167812
Drug	6,7-dimethoxyquinoline	PDGFRA PDGFRB	3.74e-05	3	81	2	CID010856252
Drug	Becaplermin	PDGFRA PDGFRB	3.74e-05	3	81	2	DB00102
Drug	AC1NSUA7	PDGFRA PDGFRB	3.74e-05	3	81	2	CID005316441
Drug	trapidil	GRK2 GRK3 PDGFRA PDGFRB	5.09e-05	57	81	4	CID000005531
Disease	emphysema imaging measurement	ZNF600 ADAMTSL1 TSHZ2 HYKK ZNF770	4.65e-05	146	79	5	EFO_0007626
Disease	oligohydramnios (biomarker_via_orthology)	PDGFRA PDGFRB	7.04e-05	5	79	2	DOID:12215 (biomarker_via_orthology)
Disease	level of Phosphatidylcholine (18:2_18:2) in blood serum	DOCK7 FADS2	1.05e-04	6	79	2	OBA_2045106
Disease	level of Phosphatidylinositol (18:1_18:2) in blood serum	DOCK7 FADS2	1.05e-04	6	79	2	OBA_2045160
Disease	1-stearoyl-2-linoleoyl-GPC (18:0/18:2) measurement	DOCK7 FADS2	1.05e-04	6	79	2	EFO_0800404
Disease	level of Phosphatidylcholine (16:0_18:0) in blood serum	DOCK7 FADS2	1.05e-04	6	79	2	OBA_2045069
Disease	1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) measurement	DOCK7 FADS2	1.47e-04	7	79	2	EFO_0800609
Disease	1-palmitoyl-2-linoleoyl-GPC (16:0/18:2) measurement	DOCK7 FADS2	1.96e-04	8	79	2	EFO_0800610
Disease	Leydig cell tumor (is_marker_for)	PDGFRA PDGFRB	1.96e-04	8	79	2	DOID:2696 (is_marker_for)
Disease	1-palmitoyl-2-stearoyl-GPC (16:0/18:0) measurement	DOCK7 FADS2	1.96e-04	8	79	2	EFO_0800396
Disease	level of Phosphatidylinositol (16:0_18:2) in blood serum	DOCK7 FADS2	1.96e-04	8	79	2	OBA_2045153
Disease	blindness (implicated_via_orthology)	RPL26 RPL26L1	1.96e-04	8	79	2	DOID:1432 (implicated_via_orthology)
Disease	level of Phosphatidylcholine (18:1_18:1) in blood serum	DOCK7 FADS2	1.96e-04	8	79	2	OBA_2045099
Disease	1-palmitoyl-2-oleoyl-GPI (16:0/18:1) measurement	DOCK7 FADS2	2.52e-04	9	79	2	EFO_0800439
Disease	1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4) measurement	DOCK7 FADS2	2.52e-04	9	79	2	EFO_0800412
Disease	1-stearoyl-2-oleoyl-GPI (18:0/18:1) measurement	DOCK7 FADS2	3.14e-04	10	79	2	EFO_0800469
Disease	oleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurement	DOCK7 FADS2	3.14e-04	10	79	2	EFO_0800333
Disease	level of Phosphatidylcholine (16:0_20:3) in blood serum	DOCK7 FADS2	3.14e-04	10	79	2	OBA_2045075
Disease	level of Phosphatidylinositol (16:0_18:1) in blood serum	DOCK7 FADS2	4.59e-04	12	79	2	OBA_2045152
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	DOCK7 FADS2	4.59e-04	12	79	2	OBA_2045157
Disease	cholesteryl ester 20:2 measurement	FADS2 THAP12	4.59e-04	12	79	2	EFO_0021440
Disease	level of Phosphatidylinositol (18:1_18:1) in blood serum	DOCK7 FADS2	5.42e-04	13	79	2	OBA_2045159
Disease	1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement	DOCK7 FADS2	5.42e-04	13	79	2	EFO_0800413
Disease	phospholipids in large VLDL measurement	KLF14 DOCK7 FADS2	6.23e-04	62	79	3	EFO_0022169
Disease	total lipids in very large VLDL measurement	KLF14 DOCK7 FADS2	6.23e-04	62	79	3	EFO_0022313
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	DOCK7 FADS2	6.31e-04	14	79	2	EFO_0022085
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	DOCK7 FADS2	6.31e-04	14	79	2	OBA_2045100
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A5	7.27e-04	15	79	2	DOID:2355 (implicated_via_orthology)
Disease	total lipids in large VLDL	KLF14 DOCK7 FADS2	7.82e-04	67	79	3	EFO_0022175
Disease	triglycerides to phosphoglycerides ratio	KLF14 DOCK7 FADS2	8.17e-04	68	79	3	EFO_0022327
Disease	free cholesterol in large VLDL measurement	KLF14 DOCK7 FADS2	8.17e-04	68	79	3	EFO_0022265
Disease	1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) measurement	DOCK7 FADS2	8.29e-04	16	79	2	EFO_0800184
Disease	level of Phosphatidylcholine (18:0_18:2) in blood serum	DOCK7 FADS2	8.29e-04	16	79	2	OBA_2045090
Disease	Manic Disorder	TENM4 GRK3 FADS2	9.26e-04	71	79	3	C0024713
Disease	hyperglycemia (implicated_via_orthology)	PCSK1 GRK2	9.38e-04	17	79	2	DOID:4195 (implicated_via_orthology)
Disease	triglycerides to total lipids in small HDL percentage	KLF14 DOCK7 FADS2	9.64e-04	72	79	3	EFO_0022336
Disease	level of Phosphatidylinositol (18:0_18:1) in blood serum	DOCK7 FADS2	1.05e-03	18	79	2	OBA_2045155
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	DOCK7 FADS2	1.05e-03	18	79	2	OBA_2045065
Disease	Crohn's disease	THEMIS TSHZ2 ZFP1 DOCK7 FADS2 ZMIZ1	1.19e-03	441	79	6	EFO_0000384
Disease	Manic	TENM4 GRK3 FADS2	1.22e-03	78	79	3	C0338831
Disease	Depression, Bipolar	TENM4 GRK3 FADS2	1.26e-03	79	79	3	C0005587
Disease	level of Phosphatidylcholine (16:0_18:2) in blood serum	DOCK7 FADS2	1.30e-03	20	79	2	OBA_2045071
Disease	longitudinal BMI measurement	PCSK1 DOCK4 ZNF257	1.40e-03	82	79	3	EFO_0005937
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	DOCK7 FADS2	1.44e-03	21	79	2	OBA_2045156
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	KLF14 DOCK7 FADS2 ZMIZ1 MAPKBP1	1.52e-03	312	79	5	EFO_0004612, EFO_0010351
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	KLF14 DOCK7 FADS2 ZMIZ1 MAPKBP1	1.59e-03	315	79	5	EFO_0004574, EFO_0004612
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	DOCK7 FADS2	1.73e-03	23	79	2	OBA_2045158
Disease	lymphocyte count	ZFAT SLC4A7 TENM4 ALMS1 AMZ1 ZFP1 KLF14 FADS2 PAPPA ZMIZ1 MUCL3	1.75e-03	1464	79	11	EFO_0004587
Disease	lipid measurement, high density lipoprotein cholesterol measurement	KLF14 DOCK7 FADS2 ZMIZ1 MAPKBP1	1.95e-03	330	79	5	EFO_0004529, EFO_0004612
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement	KLF14 DOCK7 FADS2	2.14e-03	95	79	3	EFO_0004529, EFO_0008317, EFO_0008596
Disease	chylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement	KLF14 DOCK7 FADS2	2.21e-03	96	79	3	EFO_0004530, EFO_0008317, EFO_0008596
Disease	dihomo-gamma-linolenic acid measurement	FADS2 ZNF770	2.38e-03	27	79	2	EFO_0007763
Disease	triglyceride measurement, alcohol drinking	KLF14 DOCK7 FADS2	2.41e-03	99	79	3	EFO_0004329, EFO_0004530
Disease	triglyceride measurement, alcohol consumption measurement	KLF14 DOCK7 FADS2	2.55e-03	101	79	3	EFO_0004530, EFO_0007878
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	TENM4 ZMIZ1 MUCL3	2.55e-03	101	79	3	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
INTRRIKHHFKIHVP	PRO1854	41	Q9UHT4
HSKHKNDSHIRRPCQ	nan	91	A8MT66
AKLHRHQRIHTGEKP	ZNF354C	341	Q86Y25
RGHSPFRQHKTKDKH	GRK3	386	P35626
HASLQHRKPRLARKH	AMZ1	81	Q400G9
CHHRKILHRDLKPQN	CDK18	256	Q07002
EKERHRQHHHLLQSP	ARFGEF1	221	Q9Y6D6
SKAPRADDHVRKHHS	ALMS1	2891	Q8TCU4
NSHKKRRNISDLNHP	CASP8AP2	1831	Q9UKL3
PKKTKRFPHHRLAHQ	ATG2B	1971	Q96BY7
RGHSPFRQHKTKDKH	GRK2	386	P25098
PRRHHHQTKVFAKFS	INO80	241	Q9ULG1
RKHQEALHAPTDHRE	CDC42BPG	431	Q6DT37
LHKNRDSFLSHHPEK	PDGFRA	686	P16234
RHFQHHAKPNIFHKD	FADS2	216	O95864
KSQPKLDRNHSFRHI	DAB2IP	91	Q5VWQ8
TFNLEKQNHTPRKHH	NONO	6	Q15233
QFSHNTRLKPPHKLH	GLIPR1	76	P48060
RLEKRPSSTALHQHH	LIMD1	661	Q9UGP4
PQHHLFNFRHKPEEK	EURL	116	Q9NYK6
FRNKSKLGSPHHLHE	ADAMTSL1	1321	Q8N6G6
RVHSPHKRLSHRHLK	IRAG1	101	Q9Y6F6
KFKSQQHRQGRSHHL	PTGFR	231	P43088
CRARHKKHVSPNHSS	LHX8	276	Q68G74
HQRKKQRFLSKHISH	GDPD1	31	Q8N9F7
RHLRHPAFVKKQHNG	PAPPA	441	Q13219
QRHKTHFQHPSKLHL	GRIN3A	501	Q8TCU5
HLNNPHSRHRKRIKE	THAP12	91	O43422
TQAELRHRFHVHPKS	PCDHAC1	276	Q9H158
KTLQRFHHPKLSSLH	HYKK	156	A2RU49
HRHRKKDTPVQASSH	DOCK4	186	Q8N1I0
QRKSNRHKELFALHP	DOCK7	226	Q96N67
PQRHTHTSRKKHTLE	BTBD7	916	Q9P203
NPRKHKQHHILNSSR	MAPKBP1	76	O60336
PKQFSRSDHLTKHAR	KLF14	261	Q8TD94
SDHLKQHAKVHNIRP	KLF18	1036	A0A0U1RQI7
ASHKQIHQKRKRHPE	KRCC1	151	Q9NPI7
HLAKNQGKSHRHPES	CCDC168	6926	Q8NDH2
STQENRHCKPHHQFK	CLK4	36	Q9HAZ1
RHLSHRANNFKRHPK	SLC45A1	71	Q9Y2W3
RSKDHHKHFRPIFTK	CFAP47	596	Q6ZTR5
NKHTFLQHHSDKRRP	PDGFRB	696	P09619
HEQKRHCNTTRHSKP	MUCL3	81	Q3MIW9
RSKNRKRHFNAPSHV	RPL26L1	11	Q9UNX3
DAFRKAKNRAVHHLH	MRPS5	266	P82675
ALLKRHHHQNEKRFT	SLC4A7	211	Q9Y6M7
HHHQNEKRFTSRIPL	SLC4A7	216	Q9Y6M7
PKRGHPRQNLHKHFD	TNFRSF21	331	O75509
PHKFVVHSHKALENR	SKI	256	P12755
KTKGPRHQRKHHESI	SLX4	1661	Q8IY92
DRLTQHHRHLPQKAS	APOL5	341	Q9BWW9
KKFRALHSNHRHSRD	TCEAL7	81	Q9BRU2
KRHHVDITKKLHPNQ	THEMIS	586	Q8N1K5
FSHKANLIKHQRIHT	ZFP1	221	Q6P2D0
HKFLNANRHKTRHTG	ZNF431	186	Q8TF32
QHFHRKHCFLQKPSV	ZNF451	806	Q9Y4E5
SFKRKNHLEVHRRTH	ZNF653	536	Q96CK0
KFKHSLQAHLRIHTN	ZFAT	281	Q9P243
SLNRHIKDHSGHEPK	ZNF136	116	P52737
RSKNRKRHFNAPSHI	RPL26	11	P61254
HNLSRHAVVHTREKP	ZBTB18	451	Q99592
QHLLKHQKTHSRPAT	ZNF775	176	Q96BV0
FSQKQHLLKHQRVHR	ZNF775	511	Q96BV0
LRNKDFRHSHSPAHK	TENM4	1266	Q6N022
HRHQTKKPIHRSLAD	SLC4A5	216	Q9BY07
TEQPPRHREHKKHKH	SART1	26	O43290
KKAHTHVRLPNEAHN	TSHZ2	106	Q9NRE2
RHHRLHTGEKPYKFN	ZNF813	596	Q6ZN06
KHVFHPKRAVFRHNL	PRKDC	2221	P78527
AHLKRHEQTHNEKSP	ZNF770	516	Q6IQ21
GKAFRRHSHLTEHQK	ZNF404	221	Q494X3
FSHQAGLIRHKRKHS	ZNF133	531	P52736
ERSHKLRKNNHHLFT	TJP1	756	Q07157
ILKAHQHTHSKERPF	ZNF786	551	Q8N393
KAFKQRQHLAQHHRT	ZNF471	241	Q9BX82
KSFRHPSRLTHHQKI	ZNF566	206	Q969W8
KQKFQVVKHVRRHHP	ZNF142	1631	P52746
KTFSHKPSLVHHRRL	ZNF600	561	Q6ZNG1
FINHQRIHSREKPHK	ZNF485	201	Q8NCK3
KAFQHPSHLKEHVRN	ZNF317	341	Q96PQ6
PFRKRAHLTQHNRIH	ZNF781	41	Q8N8C0
NFHKHQITHTRERPF	ZNF175	601	Q9Y473
RGDNKTSHKPLHLKH	ZMIZ1	641	Q9ULJ6
HITQHKRIHNREKPF	ZNF257	271	Q9Y2Q1
HKKTVGHQFRNSLHL	MYO5A	631	Q9Y4I1
NHYLFKHKNHPRRSR	PCSK1	66	P29120
KHKNHPRRSRRSAFH	PCSK1	71	P29120