Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DSCAM CDHR3 PCDHB3 PCDHB2 PCDH12 HMCN2 PKD1 PCDH11X CDHR4	1.30e-05	187	156	9	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	DSCAM CDHR3 PCDHB3 PCDHB2 PCDH12 HMCN2 PKD1 PCDH11X TENM1 REG3A CDHR4	2.72e-05	313	156	11	GO:0098742
Domain	FN3	DSCAM SPEG OBSCN NFASC DCC IFNAR1 LIFR ASTN1 IL5RA	3.73e-05	199	152	9	PS50853
Domain	FN3_dom	DSCAM SPEG OBSCN NFASC DCC IFNAR1 LIFR ASTN1 IL5RA	5.46e-05	209	152	9	IPR003961
Domain	PCDHB2/3	PCDHB3 PCDHB2	6.58e-05	2	152	2	IPR030735
Domain	DHR-1_domain	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	IPR027007
Domain	DHR_2	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	PS51651
Domain	DHR_1	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	PS51650
Domain	DHR-2	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	PF06920
Domain	DOCK	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	IPR026791
Domain	DOCK_C	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	IPR010703
Domain	DOCK-C2	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	PF14429
Domain	DHR-2	DOCK2 DOCK4 DOCK10	8.31e-05	11	152	3	IPR027357
Domain	ARM-type_fold	DOCK2 RALGAPA1 USP9Y RALGAPA2 MAP3K1 ITPR2 RIF1 NCAPD2 LRBA TNPO3 HTT	1.06e-04	339	152	11	IPR016024
Domain	FN3	DSCAM SPEG OBSCN NFASC DCC IFNAR1 LIFR ASTN1	1.39e-04	185	152	8	SM00060
Domain	Ig_I-set	DSCAM SPEG OBSCN NFASC DCC HEPACAM HMCN2 CD22	1.67e-04	190	152	8	IPR013098
Domain	I-set	DSCAM SPEG OBSCN NFASC DCC HEPACAM HMCN2 CD22	1.67e-04	190	152	8	PF07679
Domain	CADHERIN_1	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.25e-04	113	152	6	PS00232
Domain	Cadherin	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.25e-04	113	152	6	PF00028
Domain	CADHERIN_2	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.41e-04	114	152	6	PS50268
Domain	-	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.41e-04	114	152	6	2.60.40.60
Domain	CA	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.57e-04	115	152	6	SM00112
Domain	Cadherin-like	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	3.74e-04	116	152	6	IPR015919
Domain	ZF_ZZ_2	TADA2B HERC2 UTRN	3.94e-04	18	152	3	PS50135
Domain	ZF_ZZ_1	TADA2B HERC2 UTRN	3.94e-04	18	152	3	PS01357
Domain	ZZ	TADA2B HERC2 UTRN	3.94e-04	18	152	3	PF00569
Domain	SH3	DOCK2 DOCK4 OBSCN PPP1R13B SAMSN1 MYO15B DLG1 MACF1	3.97e-04	216	152	8	PS50002
Domain	Cadherin	CDHR3 PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	4.10e-04	118	152	6	IPR002126
Domain	SH3_domain	DOCK2 DOCK4 OBSCN PPP1R13B SAMSN1 MYO15B DLG1 MACF1	4.48e-04	220	152	8	IPR001452
Domain	Znf_ZZ	TADA2B HERC2 UTRN	4.65e-04	19	152	3	IPR000433
Domain	ZnF_ZZ	TADA2B HERC2 UTRN	4.65e-04	19	152	3	SM00291
Domain	DOCK_N	DOCK2 DOCK4	6.47e-04	5	152	2	PF16172
Domain	DOCK_N	DOCK2 DOCK4	6.47e-04	5	152	2	IPR032376
Domain	SH3_2	DOCK2 DOCK4 SAMSN1 MYO15B DLG1	6.85e-04	86	152	5	PF07653
Domain	SH3_2	DOCK2 DOCK4 SAMSN1 MYO15B DLG1	6.85e-04	86	152	5	IPR011511
Domain	IGc2	DSCAM SPEG OBSCN NFASC DCC HEPACAM HMCN2 CD22	6.91e-04	235	152	8	SM00408
Domain	Ig_sub2	DSCAM SPEG OBSCN NFASC DCC HEPACAM HMCN2 CD22	6.91e-04	235	152	8	IPR003598
Domain	Spectrin	SPTBN5 MACF1 UTRN	8.30e-04	23	152	3	PF00435
Domain	ACTININ_2	SPTBN5 MACF1 UTRN	8.30e-04	23	152	3	PS00020
Domain	ACTININ_1	SPTBN5 MACF1 UTRN	8.30e-04	23	152	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 MACF1 UTRN	8.30e-04	23	152	3	IPR001589
Domain	ITI_HC_C	ITIH1 ITIH4	9.66e-04	6	152	2	IPR010600
Domain	ITI_HC_C	ITIH1 ITIH4	9.66e-04	6	152	2	PF06668
Domain	Spectrin_repeat	SPTBN5 MACF1 UTRN	1.65e-03	29	152	3	IPR002017
Domain	ARM-like	DOCK2 DOCK10 USP9Y RIF1 NCAPD2 LRBA TNPO3 HTT	1.68e-03	270	152	8	IPR011989
Domain	VIT	ITIH1 ITIH4	1.78e-03	8	152	2	PF08487
Domain	VIT	ITIH1 ITIH4	1.78e-03	8	152	2	SM00609
Domain	Cadherin_2	PCDHB3 PCDHB2 PCDH12 PCDH11X	1.94e-03	65	152	4	PF08266
Domain	Cadherin_N	PCDHB3 PCDHB2 PCDH12 PCDH11X	1.94e-03	65	152	4	IPR013164
Domain	CH	PARVG SPTBN5 MACF1 UTRN	1.94e-03	65	152	4	SM00033
Domain	SH3	DOCK2 DOCK4 OBSCN PPP1R13B SAMSN1 MYO15B DLG1	1.97e-03	216	152	7	SM00326
Domain	Cadherin_CS	PCDHB3 PCDHB2 PCDH12 PCDH11X CDHR4	1.98e-03	109	152	5	IPR020894
Domain	fn3	DSCAM SPEG OBSCN NFASC DCC LIFR	2.13e-03	162	152	6	PF00041
Domain	SPEC	SPTBN5 MACF1 UTRN	2.20e-03	32	152	3	SM00150
Domain	Spectrin/alpha-actinin	SPTBN5 MACF1 UTRN	2.20e-03	32	152	3	IPR018159
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AMBN ACTR8 ACTR5 RBBP6 ZNF460 POLR2A CHD8 SIK3 PCMTD1 BCOR RALGAPA2 YY1 ITIH4 SETD2 HMCN2 SLC25A43 KMT5B TADA2B SMARCA1 MACF1 SDF4 PHIP ILVBL	1.53e-09	1116	158	23	31753913
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 RBBP6 POLR2A PPP1R13B CHD8 BCOR ESF1 SETD2 GTF2I MDC1 TET1 NCAPD2 DLG1 LRBA PATJ HTT	5.01e-09	549	158	16	38280479
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	ACTR8 ACTR5 POLR2A CHD8 RIF1 GTF2I KMT5B MDC1 MKI67 SMARCA1 SDF4 HERC2 TNPO3 PHIP	1.70e-07	533	158	14	30554943
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	RBBP6 POLA1 POLR2A CHD8 STAT2 ITPR2 RIF1 MDC1 NUP210 NCAPD2 MKI67	5.12e-07	341	158	11	32971831
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPEG POLR2A KSR2 OBSCN CHD8 RALGAPA2 ITPR2 SLC38A10 PKD1 NCAPD2 ZNF500 ZNF398 SDF4 LRBA HERC2 TNPO3 ALOX5 HTT AHNAK2	7.28e-07	1105	158	19	35748872
Pubmed	Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders.	DSCAM KMT5B PHIP	9.14e-07	5	158	3	33004838
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 BCOR YY1 GTF2I FAM186A MDC1 MACF1 LRBA TNPO3	1.36e-06	234	158	9	36243803
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	UBQLNL POLA1 POLR2A OBSCN ESX1 NFASC PARVG ITPR2 ZBTB44 SLC38A10 MYO15B PKD1 UTRN ALOX5 RGL4	1.49e-06	736	158	15	29676528
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	POLA1 POLR2A CHD8 ESF1 RIF1 GTF2I MDC1 NUP210 NCAPD2 MKI67 MACF1 HERC2 UTRN PHIP	1.89e-06	653	158	14	22586326
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOA2 DOCK4 RBBP6 PPP1R13B GIT2 BCOR SGO1 STAT2 RMI1 SETD2 MACF1 PATJ TRIM37	3.20e-06	588	158	13	38580884
Pubmed	Functional proteomics mapping of a human signaling pathway.	CNKSR1 RBBP6 ETS2 PPP1R13B E4F1 ZBTB44 PKD1 MACF1 SDF4 HERC2 UTRN TNPO3 ZMYM5	3.38e-06	591	158	13	15231748
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	POLA1 CHD8 BCOR SGO1 YY1 RIF1 GTF2I MDC1 TADA2B MKI67 SMARCA1 HERC2 PHIP	4.60e-06	608	158	13	36089195
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ACTR5 RBBP6 POLR2A CHD8 E4F1 BCOR ESF1 HARS2 RIF1 SETD2 MDC1 TADA2B NCAPD2 TMEM266 DLG1 MACF1 POLR1B HERC2 PATJ UTRN ILVBL	4.61e-06	1497	158	21	31527615
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	POLR2A CHD8 ESF1 ITPR2 SETD2 GTF2I MDC1 NUP210 MKI67 POLR1B HERC2	5.97e-06	440	158	11	34244565
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 POLR2A PPP1R13B BCOR SGO1 ESF1 ITPR2 PTPDC1 RIF1 CSPG5 NUP210 MKI67 DLG1 SDF4 HERC2 USP1 UTRN	6.34e-06	1049	158	17	27880917
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	POLR2A ETS2 DOCK10 CHADL RMI1 HMCN2 OSBPL6 SDF4 TNPO3	6.42e-06	283	158	9	18854154
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DOCK4 PPP1R13B NFASC OSBPL2 SACS MACF1	7.09e-06	101	158	6	9872452
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SLC9A8 DOCK10 NFASC CHD8 GIT2 ADGRV1 SIK3 MACF1	9.49e-06	225	158	8	12168954
Pubmed	A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair.	ACTR8 ACTR5 YY1	1.08e-05	10	158	3	18026119
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	POLA1 POLR2A DOCK10 CHD8 ESF1 RIN1 RIF1 GTF2I MDC1 A2ML1 NCAPD2 MKI67 SMARCA1 MACF1 POLR1B HERC2 UTRN PHIP AHNAK2	1.34e-05	1353	158	19	29467282
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 RALGAPA1 SLC9A8 KSR2 OBSCN NFASC ADGRV1 CERT1 PTPDC1 USF3 GTF2I NUP210 DLG1 MACF1 OXSR1 LRBA ALDH3B2 PATJ UTRN HTT	1.49e-05	1489	158	20	28611215
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SLC9A8 LNX2 GIT2 SIK3 SGO1 CERT1 DENND4C MAP3K1 IFNAR1 SLC38A10 SAG SLC25A43 KMT5B TET1 REG3A CFAP61 PRMT7 UBXN10	1.52e-05	1242	158	18	30973865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK2 SLC9A8 RALGAPA2 SETD2 VPS13D USF3 MYO15B SACS NUP210 MACF1 PRMT7	1.72e-05	493	158	11	15368895
Pubmed	Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.	SETD2 HTT	2.05e-05	2	158	2	24412394
Pubmed	Essential role of the N-terminal region of TFII-I in viability and behavior.	GTF2I MKI67	2.05e-05	2	158	2	20403157
Pubmed	Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor.	SETD2 HTT	2.05e-05	2	158	2	11461154
Pubmed	Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy.	IFNAR1 RNASET2	2.05e-05	2	158	2	34764281
Pubmed	SLy2 controls the antibody response to pneumococcal vaccine through an IL-5Rα-dependent mechanism in B-1 cells.	SAMSN1 IL5RA	2.05e-05	2	158	2	25330943
Pubmed	Interaction of the transcriptional activator Stat-2 with the type I interferon receptor.	STAT2 IFNAR1	2.05e-05	2	158	2	7559568
Pubmed	Separate functions for the two modules of the membrane-proximal cytokine binding domain of glycoprotein 190, the leukemia inhibitory factor low affinity receptor, in ligand binding and receptor activation.	LIFR NUP210	2.05e-05	2	158	2	11834739
Pubmed	Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor.	STAT2 IFNAR1	2.05e-05	2	158	2	9677371
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	2.05e-05	2	158	2	15185077
Pubmed	The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment.	ACTR8 ACTR5	2.05e-05	2	158	2	18163988
Pubmed	Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.	POLR2A SETD2	2.05e-05	2	158	2	16314571
Pubmed	Localization of Dlg at the mammalian neuromuscular junction.	DLG1 UTRN	2.05e-05	2	158	2	9674605
Pubmed	An Immunocompetent Mouse Model of Zika Virus Infection.	STAT2 IFNAR1	2.05e-05	2	158	2	29746837
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	DOCK2 RBBP6 POLR2A NUP210 RNASET2 LRBA USP1 PHIP NACA4P HTT	2.38e-05	419	158	10	33001583
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	AIDA GIT2 BCAS1 RALGAPA2 DENND4C RIN1 SLC38A10 OSBPL2 DLG1 MACF1 LRBA HERC2 UTRN	2.69e-05	719	158	13	35337019
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	RALGAPA1 NFASC ADGRV1 ITIH1 ITPR2 LIFR OSBPL6 DLG1 MACF1 HERC2	2.96e-05	430	158	10	32581705
Pubmed	Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.	DOCK2 DOCK4 DOCK10	3.23e-05	14	158	3	12432077
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RALGAPA1 POLR2A YY1 DENND4C STAT2 ITPR2 SETD2 MDC1 DLG1 POLR1B SDF4 PATJ USP1	3.29e-05	733	158	13	34672954
Pubmed	Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.	USP9Y RIF1 NCAPD2 HERC2	3.64e-05	41	158	4	19343720
Pubmed	INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer.	ACTR8 ACTR5 YY1	4.02e-05	15	158	3	27641337
Pubmed	The mammalian INO80 chromatin remodeling complex is required for replication stress recovery.	ACTR8 ACTR5 YY1	4.02e-05	15	158	3	25016522
Pubmed	Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling.	ACTR8 ACTR5 YY1	4.02e-05	15	158	3	21303910
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	RBBP6 CHD8 YY1 ESF1 RIF1 GTF2I MDC1 MKI67	4.89e-05	283	158	8	30585729
Pubmed	Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.	ITPR2 TET1 MKI67	4.93e-05	16	158	3	34429415
Pubmed	The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability.	ACTR8 ACTR5 YY1	4.93e-05	16	158	3	23979016
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DOCK2 OBSCN SPTBN5 RIN1 CD22 NUP210 ALOX5	5.88e-05	214	158	7	22199357
Pubmed	Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.	CHD8 GTF2I SMARCA1	5.97e-05	17	158	3	21653943
Pubmed	Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.	ACTR8 ACTR5 YY1	5.97e-05	17	158	3	26340092
Pubmed	MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor protein.	MAP3K1 PKD1	6.13e-05	3	158	2	20923779
Pubmed	Affinity of Stat2 for the subunits of the interferon alpha receptor.	STAT2 IFNAR1	6.13e-05	3	158	2	12220192
Pubmed	Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.	POLR2A E4F1	6.13e-05	3	158	2	21088222
Pubmed	Molecular recognition of agonist ligands by RXRs.	NCOA2 POLR1B	6.13e-05	3	158	2	11981034
Pubmed	Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage.	ITIH1 ITIH4	6.13e-05	3	158	2	9756925
Pubmed	Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.	IFNAR1 SETD2	6.13e-05	3	158	2	28753426
Pubmed	Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.	POLR2A SETD2	6.13e-05	3	158	2	16118227
Pubmed	Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.	SETD2 HTT	6.13e-05	3	158	2	10958656
Pubmed	An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages.	STAT2 IFNAR1	6.13e-05	3	158	2	25024400
Pubmed	Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling.	STAT2 IFNAR1	6.13e-05	3	158	2	15723812
Pubmed	CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing.	CHD8 SETD2	6.13e-05	3	158	2	36537238
Pubmed	Comparative assignments of the genes of the inter-alpha-inhibitor family in human and mouse: ITIH4 is close to ITIH1 and ITIH3, on HSA 3 and MMU 14.	ITIH1 ITIH4	6.13e-05	3	158	2	9126497
Pubmed	YY1-induced DLEU1/miR-149-5p Promotes Malignant Biological Behavior of Cholangiocarcinoma through Upregulating YAP1/TEAD2/SOX2.	DLEU1 YY1	6.13e-05	3	158	2	35864972
Pubmed	Immune response in Stat2 knockout mice.	STAT2 IFNAR1	6.13e-05	3	158	2	11163195
Pubmed	E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.	POLR2A E4F1	6.13e-05	3	158	2	21708927
Pubmed	Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.	STAT2 IFNAR1	6.13e-05	3	158	2	11786546
Pubmed	Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.	STAT2 IFNAR1	6.13e-05	3	158	2	31730616
Pubmed	Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.	STAT2 IFNAR1	6.13e-05	3	158	2	19561067
Pubmed	Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.	STAT2 IFNAR1	6.13e-05	3	158	2	35708626
Pubmed	Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6.	YY1 GTF2I	6.13e-05	3	158	2	11287625
Pubmed	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.	RALGAPA1 RALGAPA2	6.13e-05	3	158	2	19520869
Pubmed	Granulocytes in Ocular HSV-1 Infection: Opposing Roles of Mast Cells and Neutrophils.	IFNAR1 LIFR	6.13e-05	3	158	2	26066745
Pubmed	Different STAT Transcription Complexes Drive Early and Delayed Responses to Type I IFNs.	STAT2 IFNAR1	6.13e-05	3	158	2	26019270
Pubmed	Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice.	IFNAR1 LRBA	6.13e-05	3	158	2	31097594
Pubmed	Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.	DSCAM ETS2	6.13e-05	3	158	2	21079520
Pubmed	LncRNA DLEU1 contributes to colorectal cancer progression via activation of KPNA3.	DLEU1 SMARCA1	6.13e-05	3	158	2	30098595
Pubmed	Mutations in the immunoglobulin-like domain of gp190, the leukemia inhibitory factor (LIF) receptor, increase or decrease its affinity for LIF.	LIFR NUP210	6.13e-05	3	158	2	12601009
Pubmed	YY1 functions with INO80 to activate transcription.	ACTR8 ACTR5 YY1	7.14e-05	18	158	3	17721549
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	ETS2 PPP1R13B ADGRV1 LIFR MACF1 HTT	7.17e-05	152	158	6	34299191
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NCOA2 CNKSR1 ACTR8 DSCAM ETS2 USP9Y ZBTB44 SACS PKD1 DLG1 MACF1 ASTN1 LRBA HERC2 UTRN TRIM37 ZMYM5	8.17e-05	1285	158	17	35914814
Pubmed	Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.	NCOA2 POLR2A MDC1	8.45e-05	19	158	3	14578343
Pubmed	Human transcription factor protein interaction networks.	NCOA2 ACTR8 ACTR5 RBBP6 PPP1R13B CHD8 BCOR YY1 STAT2 MRPL2 RIF1 GTF2I MDC1 TADA2B MKI67 SMARCA1 HERC2 ILVBL	9.30e-05	1429	158	18	35140242
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	SPEG POLR2A OBSCN USP9Y PARVG VPS13D NCAPD2 ADGRF3 LRBA NACA4P	9.86e-05	497	158	10	36774506
Pubmed	Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.	STAT2 IFNAR1	1.22e-04	4	158	2	23653476
Pubmed	Species-Specific Pathogenicity of Severe Fever with Thrombocytopenia Syndrome Virus Is Determined by Anti-STAT2 Activity of NSs.	STAT2 IFNAR1	1.22e-04	4	158	2	30814285
Pubmed	Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains.	AMBN MKI67	1.22e-04	4	158	2	28345658
Pubmed	GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression.	NCOA2 KMT5B	1.22e-04	4	158	2	19074285
Pubmed	TRIM10 binds to IFN-α/β receptor 1 to negatively regulate type I IFN signal transduction.	STAT2 IFNAR1	1.22e-04	4	158	2	33811647
Pubmed	Zika virus spreads through infection of lymph node-resident macrophages.	STAT2 IFNAR1	1.22e-04	4	158	2	36795561
Pubmed	Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.	STAT2 IFNAR1	1.22e-04	4	158	2	15964802
Pubmed	STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor.	STAT2 IFNAR1	1.22e-04	4	158	2	21379341
Pubmed	Murine Ksr interacts with MEK and inhibits Ras-induced transformation.	CNKSR1 MAP3K1	1.22e-04	4	158	2	9427625
Pubmed	A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies.	NCOA2 ETS2	1.22e-04	4	158	2	11583620
Pubmed	IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells.	STAT2 IFNAR1	1.22e-04	4	158	2	10490982
Pubmed	Impaired type I IFN-induced Jak/STAT signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc-/- mice.	STAT2 IFNAR1	1.22e-04	4	158	2	15356134
Pubmed	The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.	POLR2A SETD2	1.22e-04	4	158	2	19141475
Pubmed	Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching.	DSCAM DCC	1.22e-04	4	158	2	25754961
Pubmed	Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis.	IFNAR1 LIFR	1.22e-04	4	158	2	23382563
Pubmed	Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii.	ETS2 IFNAR1	1.22e-04	4	158	2	1380419
GeneFamily	INO80 complex \|SRCAP complex	ACTR8 ACTR5 YY1	1.02e-04	15	113	3	595
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	TADA2B HERC2 UTRN	1.81e-04	18	113	3	91
GeneFamily	Fibronectin type III domain containing	DSCAM OBSCN NFASC DCC LIFR ASTN1	5.07e-04	160	113	6	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	DSCAM SPEG OBSCN NFASC DCC HMCN2	5.24e-04	161	113	6	593
GeneFamily	Non-clustered protocadherins	PCDH12 PCDH11X	2.45e-03	12	113	2	21
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL2 OSBPL6	2.45e-03	12	113	2	670
GeneFamily	PDZ domain containing	CNKSR1 LNX2 DLG1 PATJ AHNAK2	2.66e-03	152	113	5	1220
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	PIWIL1 PCDHB3 MYCBPAP MAP3K1 RIF1 USF3 NCAPD2 TENM1 MACF1 PHIP	2.38e-07	189	158	10	M3112
Coexpression	GABRIELY_MIR21_TARGETS	DOCK10 MAP3K1 LIFR ZBTB44 PTPDC1 GTF2I TET1 DLG1 UTRN PHIP CEP97	1.55e-06	289	158	11	M2196
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	DOCK2 SLC9A8 POLA1 RALGAPA2 VPS13D DLG1 LRBA HERC2 UTRN	3.26e-06	197	158	9	M7403
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	CERT1 DENND4C RIF1 VPS13D MACF1 HERC2 UTRN CEP97	1.66e-05	184	158	8	M9005
Coexpression	GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN	LNX2 CHADL USP9Y PARVG DENND4C MRPL2 UTRN PHIP	2.10e-05	190	158	8	M8457
Coexpression	GSE3982_MAST_CELL_VS_BASOPHIL_DN	POLR2A ETS2 GIT2 KMT5B MACF1 UTRN TRIM37 ALOX5	2.92e-05	199	158	8	M5439
Coexpression	GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP	ETS2 CHADL PARVG YY1 GTF2I NUP210 NCAPD2 DLG1	3.03e-05	200	158	8	M3863
Coexpression	ZHENG_BOUND_BY_FOXP3	LNX2 RBBP6 DOCK10 SIK3 SAMSN1 MAP3K1 ITPR2 USF3 SAG MACF1 UTRN CEP97	5.21e-05	498	158	12	M1741
Coexpression	ZHENG_BOUND_BY_FOXP3	LNX2 RBBP6 DOCK10 SIK3 SAMSN1 MAP3K1 ITPR2 USF3 SAG MACF1 UTRN CEP97	6.18e-05	507	158	12	MM1030
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	ACTR8 CHD8 SIK3 BCOR PKD1 MACF1 ZMYM5	7.15e-05	167	158	7	M361
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 ACTR8 ADGRV1 BCOR DENND4C USF3 DLG1 POLR1B UTRN CEP97	1.92e-09	193	158	10	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK2 DOCK4 DSCAM DOCK10 SAMSN1 ITPR2 RNASET2 ALOX5	6.03e-07	200	158	8	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RALGAPA1 SPEG DOCK10 USP9Y MACF1 LRBA UTRN	1.86e-06	162	158	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 PCDHB2 CHADL MYCBPAP OSBPL6 UBXN10 CDHR4	2.19e-06	166	158	7	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC9A8 CDHR3 ISM1 PCDHB3 CHD8 MAP3K1 SLC38A10	2.47e-06	169	158	7	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC9A8 CDHR3 ISM1 PCDHB3 CHD8 MAP3K1 SLC38A10	2.47e-06	169	158	7	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC9A8 CDHR3 ISM1 PCDHB3 CHD8 MAP3K1 SLC38A10	2.47e-06	169	158	7	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK10 SAMSN1 PARVG CD22 OSBPL6 TMEM266	2.77e-06	172	158	7	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK10 SAMSN1 PARVG CD22 OSBPL6 TMEM266	2.77e-06	172	158	7	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 REC114 ARL11 DOCK10 SAMSN1 NUP210 MKI67	2.88e-06	173	158	7	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	RBBP6 ETS2 CHD8 STAT2 RIF1 SETD2 UTRN	4.17e-06	183	158	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 CERT1 ITPR2 LIFR SACS UTRN TRIM37	4.64e-06	186	158	7	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	4.81e-06	187	158	7	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK10 SAMSN1 PARVG CD22 OSBPL6 TMEM266	5.16e-06	189	158	7	7ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	DOCK4 DOCK10 USP9Y RALGAPA2 LIFR CD22 MACF1	5.34e-06	190	158	7	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK2 DSCAM KSR2 DOCK10 SAMSN1 DCC NUP210	5.34e-06	190	158	7	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK10 SAMSN1 PARVG CD22 OSBPL6 TMEM266	5.53e-06	191	158	7	468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell	Ciliated-cil-3\|World / Class top	CDHR3 PPP1R13B EFHC1 CFAP61 SPAG17 UBXN10 CDHR4	5.72e-06	192	158	7	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDHR3 ADGRV1 EFHC1 SPAG17 UBXN10 CDHR4 AHNAK2	5.92e-06	193	158	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK4 ETS2 DOCK10 SAMSN1 PARVG ALOX5	6.33e-06	195	158	7	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK2 DOCK4 DOCK10 SAMSN1 ITPR2 RNASET2 UTRN	6.77e-06	197	158	7	10190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK2 DOCK4 ETS2 DOCK10 ASTL RNASET2 ALOX5	7.23e-06	199	158	7	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	COVID-19-lung\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 DOCK4 DOCK10 SAMSN1 STAT2 UTRN ALOX5	7.23e-06	199	158	7	155b03b859157013e9142e9248551369127d9204
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	7.47e-06	200	158	7	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	7.47e-06	200	158	7	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	7.47e-06	200	158	7	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	7.47e-06	200	158	7	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SOX30 OBSCN DCC C12orf50 AHNAK2	8.08e-06	77	158	5	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	REC114 SPEG PCDHB3 EFHC1 SACS FAM124A	1.33e-05	145	158	6	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	REC114 ARL11 NFASC STAT2 RIN1 UBXN10	2.48e-05	162	158	6	68c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	REC114 ARL11 NFASC STAT2 RIN1 UBXN10	2.48e-05	162	158	6	735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DOCK10 SAMSN1 CD22 ALOX5 IL5RA	2.66e-05	164	158	6	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 CARMIL2 ACTR5 DOCK10 RMI1 HARS2	3.04e-05	168	158	6	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 MYCBPAP EFHC1 OSBPL6 CFAP61 SPAG17	3.15e-05	169	158	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 MYCBPAP CFAP61 SPAG17 UBXN10 CDHR4	3.25e-05	170	158	6	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 BCAS1 EFHC1 SPAG17 UBXN10 CDHR4	3.47e-05	172	158	6	187ae91148d293537afc77e10da2b64302322224
ToppCell	Int-URO-Lymphocyte-T_NK-dnT\|Int-URO / Disease, Lineage and Cell Type	POLA1 HARS2 EFHC1 SLC25A43 LRBA PATJ	3.47e-05	172	158	6	e70299573da1679d6d286c3a43699cbff76e207d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 SGO1 PTPDC1 RIF1 NCAPD2 MKI67	3.47e-05	172	158	6	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 MYCBPAP EFHC1 OSBPL6 SPAG17 CDHR4	3.59e-05	173	158	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 PCDHB2 SGO1 SACS CSPG5 MKI67	3.59e-05	173	158	6	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 PCDHB2 SGO1 SACS CSPG5 MKI67	3.59e-05	173	158	6	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CDHR3 BCAS1 MYCBPAP SPAG17 UBXN10 CDHR4	3.71e-05	174	158	6	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CDHR3 BCAS1 MYCBPAP SPAG17 UBXN10 CDHR4	3.83e-05	175	158	6	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 ARL11 DOCK10 PARVG CD22 ALOX5	3.95e-05	176	158	6	274458d80f9f3f080248cbf64e4784ef351e7254
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 ARL11 DOCK10 PARVG CD22 ALOX5	3.95e-05	176	158	6	d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 NFASC BCAS1 EFHC1 SPAG17 CDHR4	4.21e-05	178	158	6	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	3'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A8 SAMSN1 PARVG SLC38A10 ZNF500 TRIM37	4.34e-05	179	158	6	2285e3a9018a60d7f6e974fee46b6f61d39aa76f
ToppCell	3'-Adult-Appendix-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A8 SAMSN1 PARVG SLC38A10 ZNF500 TRIM37	4.34e-05	179	158	6	0b0f27d7c5cc5ae7618d887dcfa7219df8ff1935
ToppCell	3'-Adult-Appendix-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A8 SAMSN1 PARVG SLC38A10 ZNF500 TRIM37	4.34e-05	179	158	6	63bc819df62b1f8f37bf1f17bdd4fcc161886923
ToppCell	18-Airway-Immune-Hematopoietic,_B_Cells\|Airway / Age, Tissue, Lineage and Cell class	DOCK2 ARL11 SAMSN1 PARVG CD22 ALOX5	4.48e-05	180	158	6	200cecbd8c12a4ec334583fdd5057397504de71e
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	DOCK2 DOCK10 SAMSN1 PARVG ITIH1 ALOX5	4.48e-05	180	158	6	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	facs-Thymus-Epithelium-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTR8 CARMIL2 ETS2 SLC25A43 PATJ	4.56e-05	110	158	5	3a641dced828ed97a8eea70d0a7b76f33630c9be
ToppCell	(09)_Ionocytes-(3)_72hpi\|(09)_Ionocytes / shred by cell type and Timepoint	ACTR5 YY1 ESF1 TET1 ALOX5	4.56e-05	110	158	5	fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	4.76e-05	182	158	6	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	facs-Aorta-Heart-3m-Myeloid-leukocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 ARL11 DOCK10 PARVG NUP210 MKI67	4.91e-05	183	158	6	062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 DCC PCDH11X TENM1 SPAG17	5.06e-05	184	158	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	15-Distal-Immune-Hematopoietic,_B_Cells\|Distal / Age, Tissue, Lineage and Cell class	DOCK2 CARMIL2 SAMSN1 ALOX5 IL5RA RGL4	5.06e-05	184	158	6	c294cd421f277992b56ae9c40b8f3948e33148fe
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 BCAS1 HEPACAM MYO15B CD22 FAM124A	5.06e-05	184	158	6	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 DCC PCDH11X TENM1 SPAG17	5.06e-05	184	158	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 DCC PCDH11X TENM1 SPAG17	5.06e-05	184	158	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA CDHR4	5.06e-05	184	158	6	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 BCAS1 HEPACAM MYO15B CD22 FAM124A	5.21e-05	185	158	6	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ISM1 DCC RNF150 EFHC1 PODN AHNAK2	5.21e-05	185	158	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	5.21e-05	185	158	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CDHR3 CFAP61 SPAG17 IL5RA UBXN10 CDHR4	5.21e-05	185	158	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYCBPAP CFAP61 SPAG17 IL5RA UBXN10 CDHR4	5.21e-05	185	158	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 BCAS1 HEPACAM MYO15B CD22 FAM124A	5.37e-05	186	158	6	d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	CDHR3 EFHC1 CFAP61 SPAG17 IL5RA CDHR4	5.53e-05	187	158	6	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	facs-Lung-EPCAM-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR3 FAM131C MYCBPAP CFAP61 SPAG17 UBXN10	5.53e-05	187	158	6	051b8c07d7489ce7576f6c57ce7008767ef76869
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 BCAS1 HEPACAM MYO15B CD22 FAM124A	5.53e-05	187	158	6	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR3 FAM131C MYCBPAP CFAP61 SPAG17 UBXN10	5.53e-05	187	158	6	888856cde7a69ea2f14d590597e25b1af6383c51
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	OBSCN PPP1R13B SLC5A1 RNF150 CFAP61 PATJ	5.53e-05	187	158	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 DOCK10 SIK3 MACF1 LRBA UTRN	5.70e-05	188	158	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA CDHR4	5.70e-05	188	158	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	OBSCN PPP1R13B SLC5A1 RNF150 CFAP61 PATJ	5.70e-05	188	158	6	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA CDHR4	5.70e-05	188	158	6	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDHR3 MYCBPAP OSBPL6 SPAG17 UBXN10 CDHR4	5.87e-05	189	158	6	fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	5.87e-05	189	158	6	57ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	5.87e-05	189	158	6	ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	OBSCN PPP1R13B SLC5A1 RNF150 CFAP61 PATJ	5.87e-05	189	158	6	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 FAM131C ITPR2 EFHC1 CSPG5 SPAG17	5.87e-05	189	158	6	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDHR3 MYCBPAP OSBPL6 SPAG17 UBXN10 CDHR4	5.87e-05	189	158	6	565063f9e3dd79164321f8a394bd12c176baf202
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CDHR3 MYCBPAP CFAP61 SPAG17 IL5RA CDHR4	5.87e-05	189	158	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDHR3 MYCBPAP OSBPL6 SPAG17 UBXN10 CDHR4	5.87e-05	189	158	6	497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	OBSCN PPP1R13B SLC5A1 RNF150 CFAP61 PATJ	6.04e-05	190	158	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	6.04e-05	190	158	6	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	6.04e-05	190	158	6	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	CDHR3 BCAS1 OSBPL6 SPAG17 CDHR4 AHNAK2	6.22e-05	191	158	6	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CDHR3 BCAS1 EFHC1 SPAG17 UBXN10 CDHR4	6.22e-05	191	158	6	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	CDHR3 BCAS1 OSBPL6 SPAG17 CDHR4 AHNAK2	6.22e-05	191	158	6	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	CDHR3 BCAS1 EFHC1 SPAG17 UBXN10 CDHR4	6.40e-05	192	158	6	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	ASK428-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CDHR3 BCAS1 EFHC1 SPAG17 UBXN10 CDHR4	6.40e-05	192	158	6	356ebddd03aec341b79890977edb8ff0804999a1
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	CDHR3 EFHC1 OSBPL6 SPAG17 UBXN10 CDHR4	6.59e-05	193	158	6	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 CARMIL2 DOCK10 SAMSN1 NUP210 MKI67	6.59e-05	193	158	6	326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	PCMTD1 ITPR2 DLG1 LRBA UTRN PHIP	6.59e-05	193	158	6	e6a688bc834f845ff64dae1be64f073eec5091a1
Disease	Intellectual Disability	RALGAPA1 CNKSR1 CHD8 DCC PCDH12 CERT1 YY1 SETD2 SACS RNASET2 MACF1 ASTN1 PHIP HTT	8.20e-08	447	151	14	C3714756
Disease	Abruptio Placentae	DOCK2 TDRD15 FAM124A	2.79e-05	12	151	3	EFO_1001754
Disease	response to trauma exposure	NCOA2 PIWIL1 TET1 ILVBL	1.37e-04	51	151	4	EFO_0008483
Disease	total lipids in medium VLDL	TDRD15 SIK3 CERT1 ITIH4	1.71e-04	54	151	4	EFO_0022153
Disease	mean platelet volume	LNX2 POLA1 POLR2A DOCK10 NFASC BCAS1 SIK3 BCOR CERT1 SETD2 EFHC1 OSBPL2 ADGRF3 PHIP HTT	2.46e-04	1020	151	15	EFO_0004584
Disease	Colorectal Carcinoma	GALNS OBSCN DCC LIFR SACS PCDH11X MKI67 TENM1 SDF4 SPAG17 PHIP NLRP8	2.77e-04	702	151	12	C0009402
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	TDRD15 SIK3 CERT1 GRHL1	4.40e-04	69	151	4	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	non-small cell lung carcinoma	NCOA2 DSCAM ETS2 ADGRF3	6.04e-04	75	151	4	EFO_0003060
Disease	Embryonal Rhabdomyosarcoma	BCOR SETD2	7.14e-04	8	151	2	C0206656
Disease	Profound Mental Retardation	CNKSR1 CHD8 DCC YY1 PHIP	7.62e-04	139	151	5	C0020796
Disease	Mental Retardation, Psychosocial	CNKSR1 CHD8 DCC YY1 PHIP	7.62e-04	139	151	5	C0025363
Disease	Mental deficiency	CNKSR1 CHD8 DCC YY1 PHIP	7.62e-04	139	151	5	C0917816
Disease	exploratory eye movement measurement	A2ML1 CFAP61 UTRN NLRP8	8.08e-04	81	151	4	EFO_0007700
Disease	snoring measurement	POLR2A DLEU1 ADGRV1 MACF1	9.25e-04	84	151	4	EFO_0008341
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TDRD15 CERT1 MACF1 LRBA USP1 HTT	1.02e-03	222	151	6	EFO_0008317, EFO_0020943
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	TDRD15 RMI1 MACF1 LRBA HTT	1.07e-03	150	151	5	EFO_0004611, EFO_0020947
Disease	Malignant neoplasm of breast	NCOA2 OBSCN ETS2 PANX2 SIK3 MAP3K1 RIF1 SETD2 MKI67 TENM1 MACF1 LRBA HERC2 NLRP8	1.28e-03	1074	151	14	C0006142
Disease	osteoarthritis, hip	CHADL ITIH1 HERC2 SPAG17	1.30e-03	92	151	4	EFO_1000786
Disease	Neurodevelopmental Disorders	DSCAM CERT1 SETD2 KMT5B	1.35e-03	93	151	4	C1535926
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 SIK3 CERT1 MACF1 USP1 HTT	1.49e-03	239	151	6	EFO_0008317, EFO_0020945
Disease	serum IgG glycosylation measurement	DOCK2 REC114 DSCAM BCAS1 RALGAPA2 SLC38A10 USF3 KMT5B MDC1	1.54e-03	523	151	9	EFO_0005193
Disease	fatty acid measurement	TDRD15 DLEU1 SIK3 CERT1 RMI1 MACF1 USP1 IL5RA	1.89e-03	436	151	8	EFO_0005110
Disease	Sjogren's Syndrome	GTF2I PHIP	1.96e-03	13	151	2	C1527336
Disease	Sicca Syndrome	GTF2I PHIP	1.96e-03	13	151	2	C0086981
Disease	colonic neoplasm, overall survival	ISM1 PARVG	2.27e-03	14	151	2	EFO_0000638, EFO_0004288
Disease	malignant pleural mesothelioma (is_marker_for)	NCOA2 SETD2	2.27e-03	14	151	2	DOID:7474 (is_marker_for)
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	TDRD15 SIK3 CERT1	2.29e-03	51	151	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	arm span	DSCAM CDHR3	2.61e-03	15	151	2	EFO_0005108
Disease	conotruncal heart malformations	NFASC ADGRV1 MAP3K1 NUP210	2.84e-03	114	151	4	MONDO_0016581
Disease	Inherited oocyte maturation defect	REC114 ASTL	2.98e-03	16	151	2	cv:CN238505
Disease	Substance abuse problem	DSCAM PIWIL1 ASTN1 PATJ	3.03e-03	116	151	4	C0740858
Disease	peripheral arterial disease, traffic air pollution measurement	ITPR2 EFHC1 MACF1 LRBA UTRN	3.29e-03	194	151	5	EFO_0004265, EFO_0007908
Disease	phospholipids in VLDL measurement	TDRD15 SIK3 CERT1	3.46e-03	59	151	3	EFO_0022301
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	TDRD15 CERT1 MACF1 USP1	3.52e-03	121	151	4	EFO_0008595, EFO_0020943
Disease	colorectal cancer (is_implicated_in)	DCC BCOR SETD2 MKI67	3.52e-03	121	151	4	DOID:9256 (is_implicated_in)
Disease	Sjogren syndrome	GTF2I TNPO3 PHIP	3.63e-03	60	151	3	EFO_0000699
Disease	total lipids in VLDL measurement	TDRD15 SIK3 CERT1	3.63e-03	60	151	3	EFO_0022314
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 SIK3 MACF1 USP1 HTT	3.75e-03	200	151	5	EFO_0004611, EFO_0020945
Disease	free cholesterol in VLDL measurement	TDRD15 SIK3 CERT1	3.81e-03	61	151	3	EFO_0022276
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TDRD15 SIK3 CERT1 MACF1 USP1 HTT	3.95e-03	291	151	6	EFO_0008317, EFO_0020946
Disease	smooth surface dental caries	ITPR2 RNASET2 NACA4P	3.98e-03	62	151	3	EFO_0006339
Disease	cutaneous melanoma, hair color	ADGRV1 MAP3K1 HERC2	3.98e-03	62	151	3	EFO_0000389, EFO_0003924
Disease	age at onset, smoking initiation	NCOA2 ITPR2	4.20e-03	19	151	2	EFO_0004847, EFO_0005670
Disease	cholangiocarcinoma (is_marker_for)	PANX2 MKI67 ALOX5	4.36e-03	64	151	3	DOID:4947 (is_marker_for)
Disease	cholesterol in large VLDL measurement	TDRD15 SIK3 CERT1	4.55e-03	65	151	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	TDRD15 SIK3 CERT1	4.55e-03	65	151	3	EFO_0022230
Disease	Osteoarthritis of hip	CHADL ITIH1	4.65e-03	20	151	2	C0029410

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKQEQEEPPQTTVEG	ESX1	106	Q8N693
AEEVPQILAQLPGQA	ADGRF3	501	Q8IZF5
GSQKIVEELQEPVSP	CFAP61	296	Q8NHU2
NQVTQDPIEEALGLP	CHD8	26	Q9HCK8
PEFISLPVGTVENQQ	SDF4	256	Q9BRK5
PAQPGQVLERQELES	C8orf74	206	Q6P047
QGTLEPQPASDIIDI	CSPG5	196	O95196
QEGELPLVQQQVAPS	AMBN	156	Q9NP70
VPALVPESLQEQIQS	ACTR8	31	Q9H981
LQPLGLVSDPSEQEV	CARMIL2	716	Q6F5E8
ISPQITNEVIGPELV	DLG1	121	Q12959
QLPGAEVELQLQAAP	A2ML1	571	A8K2U0
TIQENGLQIDQPPEI	ADGRV1	4366	Q8WXG9
DPGSPTDVQLVTQQV	GIT2	721	Q14161
LNGIDLTPVQDTPVA	AIDA	196	Q96BJ3
QVQPVDGVVLVDPDL	SAG	41	P10523
APEIIFQPSLIGEEQ	ACTR5	451	Q9H9F9
VVEELQQVGLDPSPD	DNHD1	1956	Q96M86
GPILPIVNVQSVDEA	ALDH3B2	256	P48448
EVTQATQPEAIPQGT	BCOR	1236	Q6W2J9
TQPEAIPQGTNITEE	BCOR	1241	Q6W2J9
QNITIPENLAPGSEV	CDHR4	241	A6H8M9
SNNEQILTEVPITPE	PPP1R13B	11	Q96KQ4
PAINQGLILEETPES	ASTL	56	Q6HA08
LDQQLPDGLVVATVP	ASTN1	766	O14525
PVNLLSDPEQGVEVT	ITIH4	756	Q14624
NGQPEVTGEPVELNT	MIP	246	P30301
VQVPDGNIQELQLIP	REC114	146	Q7Z4M0
QPDLSLPTNVQVEVI	PARVG	151	Q9HBI0
EPIEESNILSPVQDG	ITPR2	1151	Q14571
LPQALPIQVDSEEGL	PCDH12	71	Q9NPG4
ELTVDSPPVQQISQL	PCDH12	951	Q9NPG4
VQIPEDSPVGSQVAI	PCDHB2	251	Q9Y5E7
DPVGTLLQVPEQISA	OXSR1	376	O95747
QLVETLPTVGFNVEP	ARL11	36	Q969Q4
QTLVSPPEGNQEISR	CERT1	556	Q9Y5P4
PEVASIEPLGLDEQQ	NUP210	61	Q8TEM1
NQLTEIPEGLPESLE	PODN	511	Q7Z5L7
NQQDLTPIPGDSRVV	DCC	176	P43146
TVEETPRVQGETQPQ	MDC1	146	Q14676
NEEPGVILSLVQDPN	ITIH1	691	P19827
PTLEPEDLNVGETQV	NLRP8	126	Q86W28
ELGIQPVPLQTITNE	HERC2	1756	O95714
VEVQVPPQLLVAEGL	HMCN2	1711	Q8NDA2
PSPRLQVLEDGQVLQ	HMCN2	2896	Q8NDA2
GEQLQPAPVLQEEEL	KMT5B	576	Q4FZB7
ILEGNPLLQIEVEPT	KSR2	601	Q6VAB6
GTTLPVILPERNEEQ	DLEU1	36	O43261
QQPLSLPEGEITTIE	LNX2	221	Q8N448
IIADPGESQPLQEAI	FAM124A	51	Q86V42
EEQVQGPVELLSIPE	ESF1	396	Q9H501
ENELPPPENIEVSVQ	IFNAR1	226	P17181
VGNQLIPQPLDSEED	PCMTD1	291	Q96MG8
PSLNEEQTLQEVPTG	ETS2	41	P15036
VDLIPNGISIPVDQT	HERC6	836	Q8IVU3
QLPVEIDPLIASNTG	LRBA	2566	P50851
TNPTQVNGSVIDEPV	MKI67	66	P46013
AENLLEQGETPQTVP	PTPDC1	401	A2A3K4
EQGETPQTVPAQILV	PTPDC1	406	A2A3K4
VNPVNDTVVLSENIP	PCDH11X	361	Q9BZA7
QEIPLLQSVPEVNEA	RALGAPA2	1116	Q2PPJ7
SVNIIPSPDEAGEQI	OSBPL6	456	Q9BZF3
DILQDLNTETPQITP	POLA1	161	P09884
ESPGIDPSIIKQQVE	MACF1	6031	Q9UPN3
LNPPETQVEKEQITG	RBBP6	1591	Q7Z6E9
PELLEGQGAVPQTDI	OBSCN	7836	Q5VST9
QPVEDQGVSTQLLAP	MYO15B	1216	Q96JP2
NLDPVVVQEGAPLTL	NFASC	146	O94856
QEIVLGQLVLPEPNE	RGL4	106	Q8IZJ4
QEIVGGIPDSEQLLP	GALNS	111	P34059
EPVSNGVILPNGLEE	CEFIP	536	Q711Q0
EAVAVQPGEQLLSPE	HTT	2316	P42858
IDQINPPLNVTAEIE	IL5RA	236	Q01344
NPVQVLQLVEETLPD	ILVBL	446	A1L0T0
IPIVTEQPLISAGEN	GRHL1	96	Q9NZI5
QTIPGSLDIAVDNVP	DOCK10	611	Q96BY6
NTENIIPAEIPLAQE	DOCK2	76	Q92608
TPIPESQEVLQREGV	DOCK4	1386	Q8N1I0
VQTSLGEQVIVPPVD	PRMT7	201	Q9NVM4
NQSQNEELSPLVPVE	CEP97	306	Q8IW35
LQVLTVQVTDVNEPP	CDHR3	116	Q6ZTQ4
PENSPQGIVQLQDLE	FAM131C	176	Q96AQ9
VSLPNSLQEVVDPLG	DENND4C	1661	Q5VZ89
QVFLESQGIELNPPE	EFHC1	191	Q5JVL4
QENEPTVGIIPRVIQ	KIF4B	106	Q2VIQ3
IQTDPLEGVNITSPV	HEPACAM	26	Q14CZ8
QLPVLEVQPLETQVA	E4F1	411	Q66K89
ELGIPLTPQQAQALE	FAM186A	1106	A6NE01
QNLTEVPDAIPELTQ	CHADL	51	Q6NUI6
GPVIQESAEPSQLEV	GTF2I	961	P78347
LDAQVQTDPVSIGPV	BCAS1	566	O75363
ETLGQPLPDTVQDLE	SLC22A6	506	Q4U2R8
NQLVVPEGDVLLPLS	SACS	3291	Q9NZJ4
IIGLNPLPDVQVNDL	SLC38A10	1071	Q9HBR0
QNPNIQVTIEVVDGP	ISM1	121	B1AKI9
QLPPEIQESQEVTLT	CD22	146	P20273
TLNEQNVSLIPDTPE	LIFR	126	P42702
VEPEVGNVTLQPERQ	PKD1	1376	P98161
QVVDVNDNPPELTLS	PCDHB3	336	Q9Y5E6
QDVGDLIAIPAPQQI	PANX2	646	Q96RD6
VGALQVVQDTDPIPQ	RNF150	376	Q9ULK6
ALPIVPQLQVENGED	MAP3K1	1201	Q13233
LQNPLPGTVIDVEVT	PIWIL1	756	Q96J94
GSDEIILNLQVQVPP	DSCAM	1366	O60469
QPDVILEASGPEAIQ	UTRN	1931	P46939
LSQVQGEEPQRELPS	REG3A	21	Q06141
ENNSETGELQPVLPE	TRIM37	876	O94972
LLTQVRAGPEPQELQ	RIN1	386	Q13671
LLQTPTQAGEEPLNV	HARS2	341	P49590
QLEQGEPVLETPVES	STAT2	126	P52630
IVVIEDEQPGPSTSQ	SMARCA1	21	P28370
LPPLDISVAEQQQLG	TADA2B	151	Q86TJ2
ETLQTLPQEFIIPGS	TDRD15	1771	B5MCY1
IVPIAIQLNQIPGDE	ALOX5	321	P09917
IGEPDLVVSVIPNNS	RMI1	211	Q9H9A7
ESVEGIVVLENNPPG	RIF1	1316	Q5UIP0
EIIQEQENEPEPLSL	SAMSN1	306	Q9NSI8
QGESFQIEDQIPTIP	SGO1	151	Q5FBB7
QIEDQIPTIPQDTLG	SGO1	156	Q5FBB7
INPENQIVEPDGTLN	SIK3	431	Q9Y2K2
PILPVQTGEQAQQEE	SLC9A8	41	Q9Y2E8
PERGTIVPELQVVQE	TENM1	1001	Q9UKZ4
LPVIEPVSINEENEG	NSMCE4A	326	Q9NXX6
PGVDQSLQPQELREL	SLC25A43	311	Q8WUT9
DVPVAQETVQVIPGS	OSBPL2	346	Q9H1P3
VPLIGPENIVDGDQT	SPTBN5	131	Q9NRC6
DQTAQTLTGPEVPEQ	SPTBN5	1686	Q9NRC6
TLTGPEVPEQQRVVQ	SPTBN5	1691	Q9NRC6
ENLNPVPQLDIGTLE	SOX30	706	O94993
SNTVVLQEPVQEQPG	SPAG17	1671	Q6Q759
LQEPVQEQPGTLTIT	SPAG17	1676	Q6Q759
LPDIETLIGVQNPSL	TET1	166	Q8NFU7
GPEQSSEVNELNQIP	TET1	2091	Q8NFU7
ISIEPPSAQLEVQAG	AHNAK2	3026	Q8IVF2
ISIEPPSAQLEVQAG	AHNAK2	3191	Q8IVF2
LPQGEEEIPEQIANT	NCAPD2	496	Q15021
EIQEGIPLQSQSQEP	C12orf50	51	Q8NA57
DTQVPTDSRLQIQPG	CNKSR1	226	Q969H4
GIPELVSQSQAVDPE	NCOA2	1101	Q15596
PPSQDEEVQTIGQIE	RNASET2	186	O00584
PEEVSLQEQLAQGVP	ZNF460	71	Q14592
PPLNLQETQVTIEEI	RALGAPA1	176	Q6GYQ0
QETQVTIEEITPLVP	RALGAPA1	181	Q6GYQ0
LEQEIPQSVPGVQTL	PHIP	86	Q8WWQ0
PEIVNQSPVSGVTDI	SPEG	1766	Q15772
VGTVLLQIPEPQESN	REV1	986	Q9UBZ9
NDVQGPSLLIDLPVV	PATJ	991	Q8NI35
VITPDPNLSIDQVGV	POLR2A	366	P24928
TVVEEQIIGENSPPD	YY1	236	P25490
INQPDVLSQIQPEGE	ZNF398	186	Q8TD17
PGSEQVQEDLLISPQ	ZBTB44	321	Q8NCP5
IQEEPEPVSNVLQGD	MYCBPAP	46	Q8TBZ2
ALPVGTLINNVESEP	MRPL2	186	Q5T653
ADGQPVEQVVVTLPS	USF3	486	Q68DE3
PALPSIELTQQLQEE	UBQLNL	381	Q8IYU4
QPVVDGTDPITQINQ	USP9Y	1176	O00507
PVEEEEELQSQQLLP	SETD2	1916	Q9BYW2
VDPENNPTLVEVLEG	TNPO3	451	Q9Y5L0
GTDTLLIQENVNLPP	ZMYM5	476	Q9UJ78
GASDEIPELQQQVPT	UBXN10	91	Q96LJ8
PDSLVNQEVLTPGQL	POLR1B	366	Q9H9Y6
QEGPKETIEIETQVP	SLC5A1	581	P13866
QEVTQIPAALSVPEG	TRAV21	21	A0A0B4J279
GIQVEQSPPDLILQE	TRAV22	21	A0A0B4J277
EGQASQELQTLPRVP	ZSCAN5C	176	A6NGD5
NPQPAIEGGISEVEI	TMEM266	11	Q2M3C6
LESPGNTVTPVNVNE	USP1	396	O94782
GLQPLPTLEQDLEQE	ZNF500	6	O60304
PLSNENEVIETGPAV	VPS13D	3896	Q5THJ4
TETVPAIEQQLLQPQ	NACA4P	6	Q9BZK3