Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmRNA binding

CIRBP DDX17 RBMXL3 FXR2 NUP98 RBM14 RBM5 RNF40 TAF15 HNRNPA1L2 FUS YTHDF2

4.05e-066946912GO:0003729
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

GRIP1 NEFL DDX17 TCF20 HIPK1 NUP98 DVL2 RBM14 EWSR1 TAF15 FUS ZMIZ1 ATP1B2 MED12 YTHDF2

7.73e-0611606915GO:0030674
GeneOntologyMolecularFunctiontranscription coregulator activity

DDX17 TCF20 HIPK1 NUP98 RBM14 EWSR1 TAF15 FUS ZMIZ1 MED12

2.20e-055626910GO:0003712
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

CIRBP DDX17 FXR2 RNF40 TAF15 HNRNPA1L2 FUS

4.64e-05276697GO:0003730
GeneOntologyMolecularFunctionmolecular adaptor activity

GRIP1 NEFL DDX17 TCF20 HIPK1 NUP98 DVL2 RBM14 EWSR1 TAF15 FUS ZMIZ1 ATP1B2 MED12 YTHDF2

4.84e-0513566915GO:0060090
GeneOntologyMolecularFunctiontranscription coactivator activity

DDX17 TCF20 NUP98 RBM14 FUS ZMIZ1 MED12

8.34e-05303697GO:0003713
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO10 STARD9 KIF5A KIF5B

7.45e-04118694GO:0003774
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

GRIP1 DLG3 FUS

7.73e-0452693GO:0035255
GeneOntologyMolecularFunctionbeta-catenin binding

GRIP1 SOX9 MET MED12

7.93e-04120694GO:0008013
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

RBM14 ZMIZ1 MED12

1.23e-0361693GO:0030374
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF5A KIF5B

1.55e-0317692GO:0008574
GeneOntologyMolecularFunctionmicrotubule motor activity

STARD9 KIF5A KIF5B

1.83e-0370693GO:0003777
GeneOntologyBiologicalProcessRNA splicing

CIRBP DDX17 RBMXL3 NUP98 RBM14 RBM5 FAM98A TAF15 HNRNPA1L2 FUS HNRNPUL1

8.12e-075026911GO:0008380
GeneOntologyBiologicalProcesscochlea development

SOX9 ZEB1 SOBP DVL2 EYA1

1.86e-0661695GO:0090102
GeneOntologyBiologicalProcessembryonic organ morphogenesis

SOX9 OTX2 ZEB1 FOXN4 SOBP HIPK1 DVL2 EYA1 MED12

2.49e-06351699GO:0048562
GeneOntologyBiologicalProcesscochlea morphogenesis

SOX9 ZEB1 DVL2 EYA1

2.56e-0629694GO:0090103
GeneOntologyBiologicalProcessinner ear morphogenesis

SOX9 OTX2 ZEB1 SOBP DVL2 EYA1

4.62e-06129696GO:0042472
GeneOntologyBiologicalProcessmRNA metabolic process

CIRBP DDX17 RBMXL3 FXR2 NUP98 RBM14 RBM5 TAF15 HNRNPA1L2 FUS HNRNPUL1 CREB1 YTHDF2

9.32e-069176913GO:0016071
GeneOntologyBiologicalProcessear morphogenesis

SOX9 OTX2 ZEB1 SOBP DVL2 EYA1

1.28e-05154696GO:0042471
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

CIRBP DDX17 RBMXL3 FXR2 NUP98 RBM5 TAF15 FUS YTHDF2

1.62e-05443699GO:1903311
GeneOntologyBiologicalProcessembryonic organ development

SOX9 OTX2 ZEB1 FOXN4 SOBP HIPK1 LPA DVL2 EYA1 MED12

1.64e-055616910GO:0048568
GeneOntologyBiologicalProcesssensory organ morphogenesis

SOX9 OTX2 ZEB1 FOXN4 SOBP HIPK1 DVL2 EYA1

1.86e-05343698GO:0090596
GeneOntologyBiologicalProcessembryonic morphogenesis

SOX9 OTX2 ZEB1 FOXN4 SOBP HIPK1 DVL2 RBM14 EYA1 MED12 YTHDF2

2.29e-057136911GO:0048598
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

CIRBP DDX17 RBMXL3 NUP98 RBM14 RBM5 HNRNPA1L2 HNRNPUL1

2.53e-05358698GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

CIRBP DDX17 RBMXL3 NUP98 RBM14 RBM5 HNRNPA1L2 HNRNPUL1

2.53e-05358698GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

CIRBP DDX17 RBMXL3 NUP98 RBM14 RBM5 HNRNPA1L2 HNRNPUL1

2.74e-05362698GO:0000375
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SOX9 MET OTX2 ZEB1 DDX17 TCF20 EBF3 FOXN4 DVL2 RBM14 RNF40 EYA1 ZMIZ1 CREB1 MED12

4.44e-0513906915GO:0045944
GeneOntologyBiologicalProcessembryo development

SOX9 OTX2 ZEB1 FOXN4 SOBP HIPK1 LPA DVL2 RBM14 DLG3 EYA1 ZMIZ1 FOXI3 MED12 YTHDF2

6.50e-0514376915GO:0009790
GeneOntologyBiologicalProcessregulation of RNA splicing

CIRBP DDX17 RBMXL3 NUP98 RBM5 FUS

6.73e-05207696GO:0043484
GeneOntologyBiologicalProcessretrograde axonal transport

NEFL KIF5A KIF5B

6.90e-0524693GO:0008090
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

CIRBP DDX17 RBMXL3 NUP98 RBM5

7.22e-05129695GO:0048024
GeneOntologyBiologicalProcessepithelium development

SOX9 MET CDSN OTX2 ZEB1 FOXN4 LORICRIN DVL2 DLG3 EYA1 HRNR FLG2 FOXI3 CREB1 MED12

8.34e-0514696915GO:0060429
GeneOntologyBiologicalProcessalternative mRNA splicing, via spliceosome

DDX17 RBM5 HNRNPA1L2 HNRNPUL1

1.43e-0479694GO:0000380
GeneOntologyBiologicalProcessretrograde neuronal dense core vesicle transport

KIF5A KIF5B

1.64e-046692GO:1990049
GeneOntologyBiologicalProcessregulation of mRNA processing

CIRBP DDX17 RBMXL3 NUP98 RBM5

1.87e-04158695GO:0050684
GeneOntologyBiologicalProcessinner ear development

SOX9 OTX2 ZEB1 SOBP DVL2 EYA1

2.02e-04253696GO:0048839
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF5A KIF5B

2.29e-047692GO:0098971
GeneOntologyBiologicalProcessskin epidermis development

SOX9 MET HRNR FLG2 FOXI3

2.36e-04166695GO:0098773
GeneOntologyBiologicalProcessneuron fate commitment

SOX9 OTX2 FOXN4 EYA1

2.46e-0491694GO:0048663
GeneOntologyBiologicalProcessskin development

SOX9 MET CDSN LORICRIN HRNR FLG2 FOXI3

2.46e-04373697GO:0043588
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GRIP1 MET NEFL FXR2 LPA DLG3 CLSTN2 KIF5A KIF5B CREB1 SYNPR

2.47e-049316911GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GRIP1 MET NEFL FXR2 LPA DLG3 CLSTN2 KIF5A KIF5B CREB1 SYNPR

2.47e-049316911GO:0007268
GeneOntologyBiologicalProcessanimal organ morphogenesis

SOX9 MET CDSN OTX2 ZEB1 FOXN4 SOBP HIPK1 DVL2 EYA1 ZMIZ1 FOXI3 MED12

2.60e-0412696913GO:0009887
GeneOntologyBiologicalProcesspositive regulation of gene expression

CIRBP SOX9 MET RBMXL3 FXR2 NUP98 RBM14 FAM98A TAF15 HNRNPA1L2 FUS CREB1 PGC YTHDF2

2.61e-0414466914GO:0010628
GeneOntologyBiologicalProcesstrans-synaptic signaling

GRIP1 MET NEFL FXR2 LPA DLG3 CLSTN2 KIF5A KIF5B CREB1 SYNPR

2.66e-049396911GO:0099537
GeneOntologyBiologicalProcessdelamination

CDSN YTHDF2

3.05e-048692GO:0060232
GeneOntologyBiologicalProcesspositive regulation of neuron projection arborization

GRIP1 DVL2

3.05e-048692GO:0150012
GeneOntologyBiologicalProcessestablishment of skin barrier

MET HRNR FLG2

3.49e-0441693GO:0061436
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

GRIP1 MET NEFL FXR2 LPA CLSTN2 KIF5B CREB1 SYNPR

3.52e-04663699GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

GRIP1 MET NEFL FXR2 LPA CLSTN2 KIF5B CREB1 SYNPR

3.55e-04664699GO:0099177
GeneOntologyBiologicalProcessreceptor localization to synapse

GRIP1 DLG3 KIF5A KIF5B

3.67e-04101694GO:0097120
GeneOntologyBiologicalProcesssynaptic signaling

GRIP1 MET NEFL FXR2 LPA DLG3 CLSTN2 KIF5A KIF5B CREB1 SYNPR

3.70e-049766911GO:0099536
GeneOntologyBiologicalProcessneuron fate specification

SOX9 OTX2 EYA1

3.75e-0442693GO:0048665
GeneOntologyBiologicalProcesslung cell differentiation

SOX9 EYA1 CREB1

3.75e-0442693GO:0060479
GeneOntologyBiologicalProcesslung epithelial cell differentiation

SOX9 EYA1 CREB1

3.75e-0442693GO:0060487
GeneOntologyBiologicalProcessear development

SOX9 OTX2 ZEB1 SOBP DVL2 EYA1

3.82e-04285696GO:0043583
GeneOntologyBiologicalProcessanterograde axonal protein transport

KIF5A KIF5B

3.91e-049692GO:0099641
GeneOntologyBiologicalProcesssemicircular canal morphogenesis

ZEB1 EYA1

3.91e-049692GO:0048752
GeneOntologyBiologicalProcesspositive regulation of mRNA splicing, via spliceosome

CIRBP RBMXL3 NUP98

4.30e-0444693GO:0048026
GeneOntologyBiologicalProcesstype I pneumocyte differentiation

SOX9 CREB1

4.88e-0410692GO:0060509
GeneOntologyBiologicalProcessmRNA processing

CIRBP DDX17 RBMXL3 NUP98 RBM14 RBM5 HNRNPA1L2 HNRNPUL1

4.92e-04551698GO:0006397
GeneOntologyBiologicalProcesscentral nervous system development

SOX9 MET NEFL OTX2 ZEB1 FXR2 FOXN4 BRINP1 ZMIZ1 ATP1B2 CREB1 MED12

5.63e-0411976912GO:0007417
GeneOntologyBiologicalProcesspositive regulation of mRNA processing

CIRBP RBMXL3 NUP98

5.91e-0449693GO:0050685
GeneOntologyBiologicalProcessaxo-dendritic protein transport

KIF5A KIF5B

5.95e-0411692GO:0099640
GeneOntologyBiologicalProcessprotein localization to presynapse

KIF5A KIF5B

5.95e-0411692GO:1905383
GeneOntologyBiologicalProcesssemicircular canal development

ZEB1 EYA1

5.95e-0411692GO:0060872
GeneOntologyBiologicalProcessepithelial cell differentiation

SOX9 MET CDSN OTX2 ZEB1 LORICRIN EYA1 HRNR FOXI3 CREB1

6.02e-048706910GO:0030855
GeneOntologyBiologicalProcesseye morphogenesis

SOX9 OTX2 ZEB1 FOXN4 HIPK1

6.06e-04204695GO:0048592
GeneOntologyBiologicalProcessotic vesicle morphogenesis

SOX9 EYA1

7.12e-0412692GO:0071600
GeneOntologyBiologicalProcessanterograde dendritic transport

KIF5A KIF5B

7.12e-0412692GO:0098937
GeneOntologyBiologicalProcessdense core granule cytoskeletal transport

KIF5A KIF5B

7.12e-0412692GO:0099519
GeneOntologyBiologicalProcesscell fate specification

SOX9 OTX2 EYA1 FOXI3

7.72e-04123694GO:0001708
GeneOntologyBiologicalProcessanterograde axonal transport

NEFL KIF5A KIF5B

8.30e-0455693GO:0008089
GeneOntologyBiologicalProcessepidermis development

SOX9 MET CDSN LORICRIN HRNR FLG2 FOXI3

8.70e-04461697GO:0008544
GeneOntologyBiologicalProcesshead development

SOX9 MET NEFL OTX2 ZEB1 FXR2 BRINP1 ZMIZ1 ATP1B2 CREB1

9.18e-049196910GO:0060322
GeneOntologyBiologicalProcessdense core granule transport

KIF5A KIF5B

9.78e-0414692GO:1901950
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SOX9 MET FOXN4 DVL2 DLG3 EYA1 FLG2 MED12

1.05e-03619698GO:0002009
GeneOntologyBiologicalProcesslung epithelium development

SOX9 EYA1 CREB1

1.12e-0361693GO:0060428
GeneOntologyBiologicalProcessregulation of neuron projection arborization

GRIP1 DVL2

1.13e-0315692GO:0150011
GeneOntologyBiologicalProcessforebrain development

NEFL OTX2 ZEB1 FXR2 ZMIZ1 ATP1B2 CREB1

1.22e-03489697GO:0030900
GeneOntologyBiologicalProcesspositive regulation of RNA splicing

CIRBP RBMXL3 NUP98

1.23e-0363693GO:0033120
GeneOntologyBiologicalProcessmicrotubule-based protein transport

KIF5A KIF5B

1.45e-0317692GO:0099118
GeneOntologyBiologicalProcessprotein transport along microtubule

KIF5A KIF5B

1.45e-0317692GO:0098840
GeneOntologyBiologicalProcessotic vesicle development

SOX9 EYA1

1.45e-0317692GO:0071599
GeneOntologyBiologicalProcessprotein localization to cell junction

GRIP1 KIF5A KIF5B MARVELD3

1.53e-03148694GO:1902414
GeneOntologyBiologicalProcesscytoplasm organization

KIF5B ZMIZ1

1.63e-0318692GO:0007028
GeneOntologyBiologicalProcesspositive regulation of mRNA metabolic process

CIRBP RBMXL3 FXR2 NUP98 YTHDF2

1.75e-03259695GO:1903313
GeneOntologyBiologicalProcessdendritic transport

KIF5A KIF5B

1.82e-0319692GO:0098935
GeneOntologyBiologicalProcesspattern specification process

OTX2 ZEB1 FOXN4 HIPK1 DVL2 EYA1 MED12

1.86e-03526697GO:0007389
GeneOntologyBiologicalProcesscellular response to retinoic acid

SOX9 BRINP1 CREB1

1.88e-0373693GO:0071300
GeneOntologyCellularComponentcornified envelope

CDSN LORICRIN HRNR FLG2

7.55e-0569684GO:0001533
GeneOntologyCellularComponentkeratohyalin granule

HRNR FLG2

1.04e-045682GO:0036457
GeneOntologyCellularComponentpostsynaptic cytosol

KIF5A KIF5B FUS

4.24e-0445683GO:0099524
GeneOntologyCellularComponentgrowth cone

NEFL OTX2 DLG3 KIF5A KIF5B

1.21e-03245685GO:0030426
GeneOntologyCellularComponentdendritic spine head

GRIP1 FUS

1.21e-0316682GO:0044327
GeneOntologyCellularComponentciliary rootlet

KIF5A KIF5B

1.21e-0316682GO:0035253
GeneOntologyCellularComponentsite of polarized growth

NEFL OTX2 DLG3 KIF5A KIF5B

1.40e-03253685GO:0030427
GeneOntologyCellularComponentaxon cytoplasm

NEFL KIF5A KIF5B

1.42e-0368683GO:1904115
GeneOntologyCellularComponentcytosolic region

KIF5A KIF5B FUS

1.54e-0370683GO:0099522
GeneOntologyCellularComponentdendrite

GRIP1 MET FXR2 DLG3 BRINP1 CLSTN2 KIF5A KIF5B FUS

1.78e-03858689GO:0030425
GeneOntologyCellularComponentdendritic tree

GRIP1 MET FXR2 DLG3 BRINP1 CLSTN2 KIF5A KIF5B FUS

1.81e-03860689GO:0097447
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

CIRBP FXR2 HELZ KIF5A YTHDF2

1.83e-03269685GO:0036464
GeneOntologyCellularComponentribonucleoprotein granule

CIRBP FXR2 HELZ KIF5A YTHDF2

2.43e-03287685GO:0035770
GeneOntologyCellularComponentnuclear body

HMBOX1 DDX17 TCF20 HIPK1 NUP98 DVL2 RBM14 EWSR1 EYA1

2.52e-03903689GO:0016604
MousePhenoabnormal pterygoid process morphology

OTX2 ZEB1 EYA1 FOXI3

1.62e-0621594MP:0004452
MousePhenoneonatal lethality, complete penetrance

SOX9 MET CDSN OTX2 ZEB1 EBF3 HNRNPA1L2 KIF5A FUS EYA1 FOXI3

1.21e-055345911MP:0011087
MousePhenoabnormal pterygoid bone morphology

OTX2 ZEB1 FOXI3

1.53e-0512593MP:0004453
MousePhenoabnormal Meckel's cartilage morphology

SOX9 OTX2 ZEB1 FOXI3

2.58e-0541594MP:0005587
MousePhenoperinatal lethality, complete penetrance

SOX9 MET CDSN OTX2 ZEB1 EBF3 NUP98 HNRNPA1L2 KIF5A FUS EYA1 FOXI3

3.42e-057125912MP:0011089
MousePhenoabnormal cranial cartilage morphology

SOX9 OTX2 ZEB1 FOXI3

5.70e-0550594MP:0030464
MousePhenocircling

SOX9 ZEB1 TCF20 SOBP EYA1

1.32e-04117595MP:0001394
MousePhenoabnormal incus morphology

OTX2 EYA1 FOXI3

1.36e-0424593MP:0005106
MousePhenoabsent inner ear

EYA1 FOXI3

1.74e-045592MP:0006285
MousePhenoabsent pharyngeal arches

OTX2 FOXI3 MED12

1.94e-0427593MP:0003874
MousePhenoperinatal lethality

GRIP1 SOX9 MET CDSN OTX2 ZEB1 EBF3 NUP98 DVL2 HNRNPA1L2 KIF5A FUS EYA1 FOXI3

1.97e-0411305914MP:0002081
MousePhenodecreased posterior semicircular canal size

ZEB1 EYA1

2.60e-046592MP:0003164
MousePhenostereotypic behavior

SOX9 ZEB1 TCF20 SOBP BRINP1 EYA1

2.75e-04214596MP:0001408
MousePhenoabnormal endolymphatic duct morphology

SOX9 ZEB1 EYA1

2.95e-0431593MP:0006011
MousePhenorib fusion

ZEB1 DVL2 MARVELD3 EYA1

3.23e-0478594MP:0000154
MousePhenoabnormal maxilla morphology

SOX9 OTX2 ZEB1 EYA1 FOXI3

3.46e-04144595MP:0000455
MousePhenonon-midline cleft palate

SOX9 ZEB1

3.63e-047592MP:0021209
MousePhenobilateral cleft palate

SOX9 ZEB1

3.63e-047592MP:0021210
MousePhenodecreased lateral semicircular canal size

ZEB1 EYA1

3.63e-047592MP:0003162
MousePhenoabnormal malleus morphology

OTX2 EYA1 FOXI3

3.89e-0434593MP:0000029
MousePhenoabnormal eyelid morphology

GRIP1 OTX2 MYO10 LPA EYA1 ATP1B2

4.33e-04233596MP:0001340
MousePhenoneonatal lethality

SOX9 MET CDSN OTX2 ZEB1 EBF3 HNRNPA1L2 KIF5A FUS EYA1 FOXI3

4.46e-047995911MP:0002058
MousePhenoabnormal cornea stroma morphology

GRIP1 ZEB1 LPA

5.42e-0438593MP:0005300
MousePhenoabnormal pharyngeal pouch morphology

EYA1 FOXI3

6.19e-049592MP:0006031
MousePhenoabsent maxilla

OTX2 EYA1

6.19e-049592MP:0004539
MousePhenoabnormal larynx morphology

SOX9 LPA EYA1

6.31e-0440593MP:0002249
MousePhenoabnormal sphenoid bone morphology

OTX2 ZEB1 EYA1 FOXI3

6.84e-0495594MP:0000104
MousePhenoabnormal cornea epithelium morphology

GRIP1 ZEB1 LPA

7.29e-0442593MP:0006000
MousePhenoabsent outer ear

EYA1 FOXI3

7.71e-0410592MP:0005579
MousePhenoabnormal ischium morphology

SOX9 EYA1

7.71e-0410592MP:0004507
Domain-

RBM5 EWSR1 TAF15 FUS

2.59e-08106444.10.1060.10
DomainRRM_1

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

5.36e-07208648PF00076
DomainRRM

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

7.39e-07217648SM00360
Domainzf-RanBP

RBM5 EWSR1 TAF15 FUS

8.76e-0722644PF00641
DomainRRM_dom

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

1.04e-06227648IPR000504
DomainZnF_RBZ

RBM5 EWSR1 TAF15 FUS

1.06e-0623644SM00547
DomainZF_RANBP2_2

RBM5 EWSR1 TAF15 FUS

1.06e-0623644PS50199
DomainRRM

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

1.14e-06230648PS50102
DomainZF_RANBP2_1

RBM5 EWSR1 TAF15 FUS

1.27e-0624644PS01358
DomainZnf_RanBP2

RBM5 EWSR1 TAF15 FUS

1.50e-0625644IPR001876
DomainNucleotide-bd_a/b_plait

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

2.70e-06258648IPR012677
Domain-

CIRBP RBMXL3 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

1.96e-052446473.30.70.330
DomainAcyl-CoA-binding_protein

MYO10 ECI2

3.19e-048642IPR000582
DomainKinesin_motor_CS

STARD9 KIF5A KIF5B

3.73e-0441643IPR019821
DomainKINESIN_MOTOR_1

STARD9 KIF5A KIF5B

4.60e-0444643PS00411
Domain-

STARD9 KIF5A KIF5B

4.60e-04446433.40.850.10
DomainKinesin_motor_dom

STARD9 KIF5A KIF5B

4.60e-0444643IPR001752
DomainKinesin

STARD9 KIF5A KIF5B

4.60e-0444643PF00225
DomainKINESIN_MOTOR_2

STARD9 KIF5A KIF5B

4.60e-0444643PS50067
DomainKISc

STARD9 KIF5A KIF5B

4.60e-0444643SM00129
DomainS100_CABP

HRNR FLG2

3.84e-0327642PS00303
DomainIPT

MET EBF3

3.84e-0327642SM00429
DomainMARVEL

MARVELD3 SYNPR

3.84e-0327642PF01284
DomainS_100

HRNR FLG2

3.84e-0327642PF01023
DomainS100_Ca-bd_sub

HRNR FLG2

4.13e-0328642IPR013787
DomainS100/CaBP-9k_CS

HRNR FLG2

4.13e-0328642IPR001751
DomainMarvel

MARVELD3 SYNPR

4.13e-0328642IPR008253
DomainMARVEL

MARVELD3 SYNPR

4.13e-0328642PS51225
DomainS_100

HRNR FLG2

4.13e-0328642SM01394
DomainTIG

MET EBF3

5.04e-0331642PF01833
DomainIPT

MET EBF3

5.37e-0332642IPR002909
DomainP-loop_NTPase

DDX17 MYO10 STARD9 HELZ DLG3 KIF5A KIF5B HNRNPUL1

8.16e-03848648IPR027417
DomainKinesin-like_fam

KIF5A KIF5B

9.54e-0343642IPR027640
PathwayWP_MRNA_PROCESSING

CIRBP RBMXL3 FXR2 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

3.51e-05451529MM15946
PathwayWP_MIR222_IN_EXERCISEINDUCED_CARDIAC_GROWTH

HMBOX1 HIPK1

1.33e-045522MM15988
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

NEFL DLG3 CREB1

1.45e-0428523M837
PathwayREACTOME_LEISHMANIA_INFECTION

IGLV2-14 IGLV2-11 IGLV2-8 MYO10 DVL2 CREB1

1.47e-04219526M29836
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

NEFL DLG3 CREB1

2.85e-0435523MM15109
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

DDX17 AKAP8 FXR2 RBM14 HELZ EWSR1 FAM98A BRINP1 HNRNPA1L2 FUS HNRNPUL1 MED12 YTHDF2

6.67e-12462691331138677
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

DDX17 TCF20 FXR2 MYO10 RBM14 EWSR1 KIF5A FUS HNRNPUL1 CREB1 YTHDF2

3.95e-11321691132098917
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

DDX17 AKAP8 RBM14 EWSR1 FAM98A FUS HNRNPUL1 HRNR FLG2 YTHDF2

1.06e-10260691036199071
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

NEFL DDX17 AKAP8 RBM14 RBM5 EWSR1 FAM98A TAF15 KIF5B FUS HNRNPUL1 YTHDF2

8.62e-10551691234728620
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

CIRBP GRIP1 DDX17 AKAP8 FXR2 MYO10 RBM14 RBM5 EWSR1 FAM98A TAF15 HNRNPA1L2 YTHDF2

1.61e-09723691334133714
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

DDX17 AKAP8 EWSR1 TAF15 KIF5B FUS HNRNPUL1 HRNR FLG2 YTHDF2

1.69e-09346691025324306
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

CIRBP RBMXL3 FXR2 NUP98 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

1.73e-09347691016033648
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

HMBOX1 DDX17 AKAP8 FXR2 RBM14 RBM5 EWSR1 FAM98A TAF15 FUS HRNR FLG2

2.46e-09605691228977666
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

CIRBP NEFL CDSN DDX17 TCF20 AKAP8 EBF3 RBM14 RBM5 EWSR1 TAF15 HNRNPUL1 HRNR FLG2 MED12

2.65e-091082691538697112
Pubmed

Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration.

RBM14 TAF15 FUS HNRNPUL1

4.63e-091169433469008
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NEFL TCF20 FXR2 NUP98 HELZ EWSR1 TAF15 KIF5B FUS HNRNPUL1 MED12 USP47

5.77e-09653691222586326
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

CIRBP DDX17 AKAP8 FXR2 RBM14 RBM5 HELZ EWSR1 FAM98A TAF15 FUS HNRNPUL1 YTHDF2

6.00e-09807691322681889
Pubmed

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.

EWSR1 TAF15 FUS

7.47e-09369318620564
Pubmed

mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma.

EWSR1 TAF15 FUS

7.47e-09369321344536
Pubmed

Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis.

EWSR1 TAF15 FUS

7.47e-09369327311318
Pubmed

O-GlcNAc glycosylation stoichiometry of the FET protein family: only EWS is glycosylated with a high stoichiometry.

EWSR1 TAF15 FUS

7.47e-09369327903134
Pubmed

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.

EWSR1 TAF15 FUS

7.47e-09369323049996
Pubmed

A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins.

EWSR1 TAF15 FUS

7.47e-09369323975937
Pubmed

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.

EWSR1 TAF15 FUS

7.47e-09369321856723
Pubmed

Role of FET proteins in neurodegenerative disorders.

EWSR1 TAF15 FUS

7.47e-09369327415968
Pubmed

Characterization of a new brain-specific isoform of the EWS oncoprotein.

EWSR1 TAF15 FUS

7.47e-09369311422378
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

DDX17 AKAP8 FXR2 RBM14 EWSR1 FAM98A TAF15 FUS HNRNPUL1 USP47

1.09e-08421691034650049
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

CIRBP DDX17 FXR2 RBM14 EWSR1 FAM98A TAF15 FUS HNRNPUL1 HRNR

1.33e-08430691038172120
Pubmed

Human transcription factor protein interaction networks.

CIRBP HMBOX1 SOX9 ZEB1 TCF20 AKAP8 SOBP NUP98 HELZ EWSR1 ZMIZ1 HNRNPUL1 HRNR FLG2 CREB1 YTHDF2

1.48e-081429691635140242
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

CIRBP HMBOX1 ZEB1 TCF20 RBM5 EWSR1 TAF15 FUS HNRNPUL1 MED12

2.18e-08453691029656893
Pubmed

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

CIRBP ZEB1 DDX17 RBM14 EWSR1 TAF15 FUS HNRNPUL1 YTHDF2

2.24e-0833669931253590
Pubmed

Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.

CIRBP DDX17 RBMXL3 RBM14 EWSR1 TAF15 HNRNPUL1

2.38e-0815369728225217
Pubmed

Post-transcriptional regulation of FUS and EWS protein expression by miR-141 during neural differentiation.

EWSR1 TAF15 FUS

2.99e-08469328453628
Pubmed

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites.

GRIP1 KIF5A KIF5B

2.99e-08469311986669
Pubmed

The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.

EWSR1 TAF15 FUS

2.99e-08469330398641
Pubmed

The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription.

EWSR1 TAF15 FUS

2.99e-0846939660765
Pubmed

A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1.

DDX17 FXR2 RBM14 TAF15 FUS

3.05e-084569525496916
Pubmed

Interaction network of human early embryonic transcription factors.

OTX2 ZEB1 TCF20 SOBP NUP98 ZMIZ1 HRNR FLG2 MED12

3.26e-0835169938297188
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

AKAP8 RBM14 TAF15 KIF5B FUS HNRNPUL1 HRNR

4.18e-0816669735687106
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

CIRBP DDX17 AKAP8 FXR2 RBM14 EWSR1 FUS YTHDF2

4.65e-0825869837794589
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NEFL ZEB1 TCF20 AKAP8 FXR2 EBF3 DVL2 DLG3 EWSR1 TAF15 KIF5A KIF5B FUS

4.78e-08963691328671696
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

CIRBP DDX17 RBMXL3 RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 KIF5A KIF5B FUS HNRNPUL1 HRNR YTHDF2

5.06e-081153691429845934
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

DDX17 AKAP8 FXR2 NUP98 RBM14 HELZ EWSR1 TAF15 FUS HNRNPUL1 YTHDF2

6.59e-08655691135819319
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

DDX17 TCF20 AKAP8 RBM5 EWSR1 FUS HNRNPUL1 YTHDF2

7.39e-0827469834244482
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

DDX17 AKAP8 FXR2 RBM14 HELZ EWSR1 FAM98A TAF15 FUS HNRNPUL1 YTHDF2

9.33e-08678691130209976
Pubmed

Revealing A-Raf functions through its interactome.

DDX17 AKAP8 RBM14 EWSR1 TAF15 FUS HRNR

9.45e-0818769729777862
Pubmed

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription.

EWSR1 TAF15 FUS

1.49e-07669318509338
Pubmed

The hnRNP RALY regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization.

EWSR1 TAF15 FUS

1.49e-07669330354839
Pubmed

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.

FXR2 EWSR1 FAM98A TAF15 HNRNPA1L2 FUS

1.65e-0712269629530978
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

RBM5 EWSR1 KIF5A FUS YTHDF2

2.70e-076969532238831
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

TCF20 AKAP8 NUP98 RBM14 HELZ EWSR1 FUS ZMIZ1 YTHDF2

3.05e-0745769932344865
Pubmed

Landscape of the SOX2 protein-protein interactome.

DDX17 RBM14 EWSR1 FAM98A TAF15 FUS

3.13e-0713669621280222
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

DDX17 TCF20 NUP98 RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 FUS HNRNPUL1 CREB1 YTHDF2

3.55e-07954691236373674
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MET DDX17 AKAP8 NUP98 RBM14 RBM5 DLG3 TAF15 HNRNPUL1 HRNR FLG2

3.62e-07777691135844135
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

DDX17 AKAP8 RBM14 EWSR1 TAF15 FUS HNRNPUL1 YTHDF2

3.83e-0734069824332808
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CIRBP CDSN RBMXL3 AKAP8 FXR2 STARD9 RBM14 RBM5 EWSR1 FAM98A TAF15 KIF5B FLG2 YTHDF2

4.16e-071371691436244648
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

CIRBP DDX17 AKAP8 FXR2 MYO10 RBM14 FAM98A HNRNPA1L2 ECI2 FUS FLG2 YTHDF2

4.28e-07971691233306668
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

CIRBP FXR2 RBM14 TAF15 HNRNPA1L2 FUS

4.95e-0714769628977470
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

DDX17 AKAP8 RBM14 EWSR1 TAF15 FUS HNRNPUL1

5.72e-0724469729884807
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

DDX17 AKAP8 RBM14 EWSR1 FAM98A TAF15 KIF5B FUS HNRNPUL1

5.83e-0749469926831064
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

DDX17 AKAP8 RBM14 EWSR1 HNRNPA1L2 FUS YTHDF2

5.88e-0724569721182205
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

DDX17 RBM14 TAF15 FUS HRNR FLG2 YTHDF2

5.88e-0724569735652658
Pubmed

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

TCF20 NUP98 RBM14 TAF15 FUS HNRNPUL1

6.03e-0715269628192407
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NEFL DDX17 TCF20 AKAP8 NUP98 RBM14 EWSR1 TAF15 KIF5B FUS HNRNPUL1 HRNR

7.49e-071024691224711643
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

DDX17 RBMXL3 RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 FUS HNRNPUL1 HRNR YTHDF2

8.15e-07844691125963833
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

CIRBP DDX17 AKAP8 FXR2 NUP98 RBM14 RBM5 EWSR1 FAM98A TAF15 FUS

8.44e-07847691135850772
Pubmed

Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics.

EWSR1 FUS HNRNPUL1

8.88e-071069321956701
Pubmed

Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.

CIRBP DDX17 RBM14 RBM5 FAM98A FUS HNRNPUL1 YTHDF2

9.54e-0738469831059266
Pubmed

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.

DDX17 AKAP8 RBM14 EWSR1 BRINP1

9.67e-078969522446626
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GRIP1 TCF20 AKAP8 STARD9 RBM14 HELZ FAM98A KIF5B HNRNPUL1 YTHDF2 DOP1A

9.90e-07861691136931259
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

DDX17 AKAP8 RBM14 EWSR1 RNF40 FAM98A TAF15 HNRNPA1L2 KIF5B FUS HNRNPUL1 MED12 YTHDF2

9.94e-071257691337317656
Pubmed

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.

AKAP8 FAM98A TAF15 EYA1 HNRNPUL1

1.02e-069069533087562
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

HMBOX1 DDX17 TCF20 AKAP8 NUP98 RBM14 RBM5 EWSR1 RNF40 TAF15 FUS HNRNPUL1 CREB1

1.37e-061294691330804502
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

CIRBP DDX17 FXR2 NUP98 RBM14 EWSR1 TAF15 KIF5B ECI2 FUS

1.37e-06711691033022573
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

DDX17 EWSR1 HNRNPA1L2 KIF5B FUS HNRNPUL1 ATP1B2 SYNPR YTHDF2

1.46e-0655269936293380
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

CIRBP DDX17 RBM14 EWSR1 TAF15 FUS MED12

1.54e-0628369728533407
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CIRBP DDX17 TCF20 EBF3 RBM14 RBM5 EWSR1 KIF5B FUS HNRNPUL1 CREB1 MED12

1.62e-061103691234189442
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

CIRBP DDX17 EWSR1 FUS HNRNPUL1 HRNR FLG2

1.65e-0628669732041737
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

ZEB1 DDX17 TCF20 AKAP8 EWSR1 RNF40 FUS HRNR

2.03e-0642569824999758
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

DDX17 FXR2 RBM14 EWSR1 TAF15 FUS HRNR

2.16e-0629869730737378
Pubmed

ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.

DDX17 EWSR1 TAF15 FUS

2.17e-064669420890123
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

DDX17 FXR2 MYO10 RBM14 EWSR1 FAM98A FUS HNRNPUL1 HRNR

2.18e-0658069935676659
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

FXR2 NUP98 HELZ FAM98A HNRNPUL1 CTTNBP2NL YTHDF2

3.12e-0631569726777405
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

DDX17 AKAP8 RBM14 HELZ ECI2 HNRNPUL1 YTHDF2

3.25e-0631769730997501
Pubmed

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.

CIRBP DDX17 RBM5 FUS HNRNPUL1

3.44e-0611569517332742
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CIRBP DDX17 FXR2 PRIM2 RBM14 EWSR1 RNF40 FAM98A KIF5B ECI2 FUS HNRNPUL1 FLG2

3.66e-061415691328515276
Pubmed

Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion: a new tumor entity.

EWSR1 CREB1

3.88e-06269221997693
Pubmed

Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS.

EWSR1 FUS

3.88e-0626928921363
Pubmed

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory.

KIF5A KIF5B

3.88e-06269231961321
Pubmed

c-Met and CREB1 are involved in miR-433-mediated inhibition of the epithelial-mesenchymal transition in bladder cancer by regulating Akt/GSK-3β/Snail signaling.

MET CREB1

3.88e-06269226844702
Pubmed

A morphologic and molecular reappraisal of myoepithelial tumors of soft tissue, bone, and viscera with EWSR1 and FUS gene rearrangements.

EWSR1 FUS

3.88e-06269231994243
Pubmed

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.

EWSR1 TAF15

3.88e-06269222454397
Pubmed

EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions.

EWSR1 FUS

3.88e-06269226573619
Pubmed

Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes.

TAF15 FUS

3.88e-0626929795213
Pubmed

Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration.

KIF5A KIF5B

3.88e-06269235259089
Pubmed

Generation of human embryonic stem cell models to exploit the EWSR1-CREB fusion promiscuity as a common pathway of transformation in human tumors.

EWSR1 CREB1

3.88e-06269234193943
Pubmed

Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins.

EWSR1 TAF15

3.88e-0626928954779
Pubmed

EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.

EWSR1 CREB1

3.88e-06269217724745
Pubmed

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells.

KIF5A KIF5B

3.88e-0626921607388
Pubmed

DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner.

DDX17 FUS

3.88e-06269234061233
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NEFL DDX17 STARD9 NUP98 RBM5 DLG3 FAM98A TAF15 HNRNPA1L2 KIF5A KIF5B FUS DOP1A

4.50e-061442691335575683
Pubmed

The role of Pax2 in mouse inner ear development.

NEFL OTX2 EYA1

4.98e-061769315242798
Pubmed

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.

DDX17 NUP98 RBM14 EWSR1 FUS HNRNPUL1

5.14e-0622069634091597
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

DDX17 TCF20 RBM14 RNF40 HNRNPUL1 MED12

5.14e-0622069635785414
Pubmed

Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.

SOX9 ZEB1 LORICRIN

5.97e-061869324735878
InteractionCUL2 interactions

CIRBP SOX9 DDX17 MYO10 RBM14 DLG3 EWSR1 FAM98A TAF15 KIF5B FUS HNRNPUL1 HRNR FLG2

8.56e-095916814int:CUL2
InteractionZBTB7B interactions

DDX17 TCF20 FXR2 MYO10 RBM14 EWSR1 KIF5A FUS HNRNPUL1 CREB1 YTHDF2

3.71e-083666811int:ZBTB7B
InteractionCREBBP interactions

GRIP1 SOX9 ZEB1 DDX17 HIPK1 NUP98 RBM5 HELZ EWSR1 KIF5A FUS CREB1 YTHDF2

8.69e-085996813int:CREBBP
InteractionNUP35 interactions

TCF20 AKAP8 NUP98 RBM14 HELZ EWSR1 HNRNPA1L2 FUS ZMIZ1 YTHDF2 USP47

1.64e-074246811int:NUP35
InteractionMECP2 interactions

CIRBP NEFL CDSN DDX17 TCF20 AKAP8 FXR2 EBF3 RBM14 RBM5 EWSR1 TAF15 FUS HNRNPUL1 HRNR FLG2 CREB1 MED12

1.66e-0712876818int:MECP2
InteractionCHD3 interactions

HMBOX1 NEFL DDX17 AKAP8 FXR2 RBM14 RBM5 EWSR1 FAM98A TAF15 FUS HRNR FLG2 CREB1

1.85e-077576814int:CHD3
InteractionFMR1 interactions

CIRBP HMBOX1 NEFL TCF20 AKAP8 FXR2 DVL2 RBM14 EWSR1 KIF5A KIF5B YTHDF2

2.08e-075366812int:FMR1
InteractionBTRC interactions

SOX9 DDX17 AKAP8 MYO10 RBM14 RBM5 EWSR1 FAM98A FUS HNRNPUL1 HRNR FLG2 YTHDF2 USP47

2.46e-077756814int:BTRC
InteractionTLE3 interactions

SOX9 DDX17 TCF20 AKAP8 EBF3 RBM14 HELZ TAF15 ZMIZ1 USP47

5.04e-073766810int:TLE3
InteractionGLDC interactions

DDX17 TCF20 AKAP8 RBM5 EWSR1 FUS HNRNPUL1 CREB1 YTHDF2

1.27e-06321689int:GLDC
InteractionDDX17 interactions

OTX2 ZEB1 DDX17 FXR2 RBM14 RBM5 EWSR1 TAF15 FUS HNRNPUL1

1.56e-064266810int:DDX17
InteractionDDX3X interactions

DDX17 FXR2 RBM14 EWSR1 FAM98A TAF15 FUS HNRNPUL1 HRNR FLG2 MED12 YTHDF2

1.62e-066516812int:DDX3X
InteractionBMI1 interactions

CIRBP AKAP8 FXR2 RBM14 HELZ EWSR1 TAF15 KIF5B FUS HNRNPUL1 MED12 YTHDF2

1.84e-066596812int:BMI1
InteractionPRMT1 interactions

CIRBP GRIP1 NEFL DDX17 AKAP8 RBM14 RBM5 EWSR1 FAM98A TAF15 KIF5B FUS HNRNPUL1 YTHDF2

2.14e-069296814int:PRMT1
InteractionHNRNPA1 interactions

CIRBP DDX17 AKAP8 RBM14 RBM5 EWSR1 TAF15 BRINP1 HNRNPA1L2 FUS HNRNPUL1 HRNR FLG2 YTHDF2

2.61e-069456814int:HNRNPA1
InteractionTRIM31 interactions

DDX17 AKAP8 FXR2 RBM14 EWSR1 FAM98A TAF15 FUS HNRNPUL1 USP47

2.76e-064546810int:TRIM31
InteractionDDX5 interactions

OTX2 ZEB1 DDX17 AKAP8 RBM14 EWSR1 RNF40 TAF15 FUS HNRNPUL1 MED12

2.89e-065686811int:DDX5
InteractionYWHAG interactions

GRIP1 NEFL DDX17 AKAP8 STARD9 DVL2 RBM14 HELZ EWSR1 FAM98A TAF15 KIF5A KIF5B HNRNPUL1 YTHDF2 DOP1A

2.92e-0612486816int:YWHAG
InteractionCOPS5 interactions

CIRBP ZEB1 DDX17 AKAP8 RBM14 RBM5 EWSR1 FAM98A TAF15 KIF5B FUS HNRNPUL1 HRNR FLG2 YTHDF2

3.06e-0611026815int:COPS5
InteractionOTUB1 interactions

DVL2 EWSR1 RNF40 DNAJB7 KIF5B FUS EYA1 YTHDF2 USP47

3.12e-06358689int:OTUB1
InteractionKHDRBS1 interactions

CIRBP OTX2 DDX17 FXR2 RBM14 DLG3 EWSR1 FUS MED12

4.36e-06373689int:KHDRBS1
InteractionARAF interactions

CIRBP DDX17 AKAP8 DVL2 RBM14 EWSR1 TAF15 FUS HRNR

4.65e-06376689int:ARAF
InteractionHDLBP interactions

CIRBP CDSN RBMXL3 AKAP8 FXR2 RBM14 RBM5 EWSR1 TAF15 KIF5B FLG2 YTHDF2 USP47

4.75e-068556813int:HDLBP
InteractionARMC5 interactions

AKAP8 RBM14 TAF15 KIF5B FUS HNRNPUL1 HRNR

5.12e-06201687int:ARMC5
InteractionSIRT7 interactions

NEFL TCF20 FXR2 NUP98 HELZ EWSR1 TAF15 KIF5B FUS HNRNPUL1 MED12 USP47

6.40e-067446812int:SIRT7
InteractionFZR1 interactions

CIRBP MET DDX17 AKAP8 FXR2 MYO10 NUP98 RBM14 FAM98A HNRNPA1L2 ECI2 FUS EYA1 FLG2 YTHDF2

6.48e-0611726815int:FZR1
InteractionCAND1 interactions

CIRBP DDX17 AKAP8 FXR2 MYO10 RBM14 EWSR1 RNF40 FAM98A TAF15 FUS HNRNPUL1 YTHDF2

7.69e-068946813int:CAND1
InteractionSNRNP40 interactions

DDX17 TCF20 AKAP8 PRIM2 RBM14 RBM5 EWSR1 TAF15 FUS HNRNPUL1 MED12

8.61e-066376811int:SNRNP40
InteractionDAZL interactions

FXR2 HELZ FAM98A TAF15 HNRNPUL1 YTHDF2

9.48e-06145686int:DAZL
InteractionMYCN interactions

CIRBP DDX17 TCF20 AKAP8 FXR2 LORICRIN RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 FUS HNRNPUL1 HRNR FLG2 CREB1

9.86e-0613736816int:MYCN
InteractionEP300 interactions

GRIP1 SOX9 ZEB1 DDX17 AKAP8 NUP98 DVL2 RBM14 EWSR1 RNF40 TAF15 KIF5B FUS HNRNPUL1 CREB1 SLC33A1

1.27e-0514016816int:EP300
InteractionRC3H2 interactions

DDX17 AKAP8 FXR2 RBM14 HELZ EWSR1 FAM98A TAF15 FUS HNRNPUL1 YTHDF2

1.32e-056676811int:RC3H2
InteractionFXR2 interactions

GRIP1 HMBOX1 DDX17 FXR2 RBM14 HELZ EWSR1 FAM98A YTHDF2

1.36e-05430689int:FXR2
InteractionYAP1 interactions

ZEB1 DDX17 TCF20 RBM14 HNRNPA1L2 KIF5A KIF5B FUS HNRNPUL1 HRNR FLG2 CREB1 MED12 USP47

1.41e-0510956814int:YAP1
InteractionMETTL14 interactions

DDX17 RBM14 EWSR1 KIF5A KIF5B ECI2 FUS HNRNPUL1 HRNR FLG2

1.68e-055586810int:METTL14
InteractionCDK9 interactions

DDX17 MYO10 NUP98 RBM14 EWSR1 RNF40 TAF15 KIF5B FUS PGC MED12

1.70e-056856811int:CDK9
InteractionRNF113A interactions

DDX17 AKAP8 FXR2 NUP98 RBM14 HELZ EWSR1 TAF15 FUS HNRNPUL1 YTHDF2

1.86e-056926811int:RNF113A
InteractionCIT interactions

NEFL DDX17 RBMXL3 TCF20 FXR2 HIPK1 NUP98 RBM14 RBM5 RNF40 FAM98A TAF15 HNRNPA1L2 ECI2 FUS HNRNPUL1

1.95e-0514506816int:CIT
InteractionFBP1 interactions

CIRBP DDX17 FXR2 EWSR1 FUS HNRNPUL1 HRNR FLG2

2.19e-05348688int:FBP1
InteractionMIRLET7D interactions

RBM14 RBM5 FAM98A TAF15 FUS

2.32e-05101685int:MIRLET7D
InteractionRBMX interactions

CIRBP DDX17 FXR2 RBM14 EWSR1 TAF15 HNRNPA1L2 FUS HNRNPUL1

2.36e-05461689int:RBMX
InteractionNFX1 interactions

CIRBP DDX17 FXR2 RBM14 RBM5 FAM98A FUS HNRNPUL1 YTHDF2

2.57e-05466689int:NFX1
InteractionCTNNB1 interactions

GRIP1 HMBOX1 MET DDX17 NUP98 DVL2 RBM14 EWSR1 KIF5B FUS ZMIZ1 CREB1 YTHDF2

2.77e-0510096813int:CTNNB1
InteractionMIRLET7E interactions

RBM14 RBM5 FAM98A TAF15 FUS

2.93e-05106685int:MIRLET7E
InteractionNKX2-1 interactions

TCF20 NUP98 RBM14 TAF15 FUS HNRNPUL1

3.23e-05180686int:NKX2-1
InteractionDCUN1D1 interactions

DVL2 EWSR1 RNF40 TAF15 FUS HNRNPUL1 FLG2

3.89e-05275687int:DCUN1D1
InteractionMIRLET7I interactions

RBM14 RBM5 FAM98A TAF15 FUS

4.16e-05114685int:MIRLET7I
InteractionHNF1B interactions

HMBOX1 SOX9 OTX2 ZEB1 EWSR1 CREB1

4.37e-05190686int:HNF1B
InteractionEWSR1 interactions

OTX2 ZEB1 DDX17 TCF20 AKAP8 FXR2 EWSR1 RNF40 TAF15 FUS HNRNPUL1 HRNR

4.51e-059066812int:EWSR1
InteractionRNU1-1 interactions

EWSR1 TAF15 FUS

4.68e-0521683int:RNU1-1
InteractionMIRLET7G interactions

RBM14 RBM5 FAM98A TAF15 FUS

4.71e-05117685int:MIRLET7G
InteractionHEXIM1 interactions

CIRBP DDX17 RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 KIF5A KIF5B FUS HNRNPUL1 HRNR

4.86e-059136812int:HEXIM1
InteractionSAFB2 interactions

RBM14 EWSR1 RNF40 TAF15 FUS HNRNPUL1

5.05e-05195686int:SAFB2
InteractionCELF1 interactions

RBM5 HELZ EWSR1 TAF15 FUS HNRNPUL1 YTHDF2

5.21e-05288687int:CELF1
InteractionBRCA1 interactions

HMBOX1 DDX17 AKAP8 FXR2 RBM14 EWSR1 FAM98A TAF15 KIF5B FUS ZMIZ1 HNRNPUL1 CREB1 MED12

6.02e-0512496814int:BRCA1
InteractionTARDBP interactions

DDX17 HELZ EWSR1 FAM98A TAF15 FUS HNRNPUL1 ATP1B2 YTHDF2

6.03e-05520689int:TARDBP
InteractionSOX2 interactions

ZEB1 DDX17 TCF20 AKAP8 NUP98 RBM14 RBM5 HELZ EWSR1 FAM98A TAF15 FUS EYA1 CREB1 YTHDF2

6.27e-0514226815int:SOX2
InteractionFUBP3 interactions

FXR2 RBM14 HELZ FAM98A FUS HNRNPUL1 YTHDF2

6.32e-05297687int:FUBP3
InteractionUBE2I interactions

GRIP1 HMBOX1 SOX9 HIPK1 NUP98 RBM14 RNF40 TAF15 FUS CREB1

6.44e-056546810int:UBE2I
InteractionCPSF6 interactions

DDX17 AKAP8 FXR2 RBM14 EWSR1 TAF15 KIF5B FUS HNRNPUL1

6.58e-05526689int:CPSF6
InteractionTAF15 interactions

CIRBP DDX17 RBM14 EWSR1 TAF15 FUS HNRNPUL1 MED12

6.74e-05408688int:TAF15
InteractionRBM45 interactions

DDX17 FXR2 RBM14 EWSR1 FUS HNRNPUL1

7.04e-05207686int:RBM45
InteractionMARF1 interactions

FXR2 EBF3 RBM5 HELZ YTHDF2

7.23e-05128685int:MARF1
InteractionTP53BP1 interactions

CIRBP HMBOX1 ZEB1 RBM5 EWSR1 TAF15 FUS HNRNPUL1 MED12

7.28e-05533689int:TP53BP1
InteractionSF1 interactions

CIRBP DDX17 EWSR1 TAF15 ECI2 FUS HNRNPUL1

7.32e-05304687int:SF1
InteractionKHDRBS2 interactions

CIRBP DDX17 RBM14 EWSR1 HRNR

7.50e-05129685int:KHDRBS2
InteractionEFTUD2 interactions

CIRBP DDX17 FXR2 PRIM2 RBM14 EWSR1 RNF40 FAM98A TAF15 KIF5B ECI2 FUS HNRNPUL1 FLG2 MED12

7.76e-0514496815int:EFTUD2
InteractionTDRD3 interactions

FXR2 HELZ EWSR1 FAM98A FUS YTHDF2

8.03e-05212686int:TDRD3
InteractionMIR138-1 interactions

RBM14 FAM98A TAF15 FUS

8.20e-0568684int:MIR138-1
InteractionRC3H1 interactions

CIRBP DDX17 FXR2 RBM14 HELZ EWSR1 FAM98A FUS HNRNPUL1 YTHDF2

8.58e-056776810int:RC3H1
InteractionPRC1 interactions

NEFL DDX17 RBMXL3 AKAP8 FXR2 NUP98 RBM14 TAF15 HNRNPA1L2 FUS HNRNPUL1 HRNR

8.95e-059736812int:PRC1
InteractionMIR9-3 interactions

RBM14 FAM98A TAF15 FUS

9.19e-0570684int:MIR9-3
InteractionRNF43 interactions

DDX17 TCF20 AKAP8 FXR2 NUP98 DVL2 RBM14 HELZ

9.25e-05427688int:RNF43
InteractionCMTR1 interactions

CIRBP DDX17 FXR2 RBM5 RNF40 FUS

9.36e-05218686int:CMTR1
InteractionMIR140 interactions

RBM14 FAM98A TAF15 FUS

9.72e-0571684int:MIR140
InteractionSMG7 interactions

TCF20 FXR2 RBM5 HELZ RNF40 HNRNPUL1 YTHDF2

9.88e-05319687int:SMG7
InteractionRTRAF interactions

OTX2 ZEB1 FXR2 FAM98A FUS YTHDF2

1.03e-04222686int:RTRAF
InteractionAR interactions

GRIP1 NEFL DDX17 TCF20 RBM14 RNF40 TAF15 ZMIZ1 HNRNPUL1 HRNR CREB1 MED12

1.08e-049926812int:AR
InteractionMIR18A interactions

RBM14 FAM98A TAF15 FUS

1.08e-0473684int:MIR18A
InteractionMIR29B1 interactions

RBM14 FAM98A TAF15 FUS

1.08e-0473684int:MIR29B1
InteractionSRSF9 interactions

RBM14 EWSR1 RNF40 TAF15 FUS HNRNPUL1

1.09e-04224686int:SRSF9
InteractionZNF326 interactions

RBM14 EWSR1 RNF40 TAF15 BRINP1 FUS

1.09e-04224686int:ZNF326
InteractionRUNX1 interactions

DDX17 HIPK1 RBM14 EWSR1 TAF15 FUS MED12

1.09e-04324687int:RUNX1
InteractionSFPQ interactions

OTX2 DDX17 FXR2 RBM14 EWSR1 FAM98A TAF15 FUS YTHDF2

1.10e-04563689int:SFPQ
InteractionMIR20A interactions

RBM14 FAM98A TAF15 FUS

1.14e-0474684int:MIR20A
InteractionSMC5 interactions

DDX17 TCF20 NUP98 RBM14 EWSR1 FAM98A TAF15 HNRNPA1L2 FUS HNRNPUL1 CREB1 YTHDF2

1.16e-0410006812int:SMC5
InteractionCUL5 interactions

CIRBP SOX9 EWSR1 FAM98A TAF15 FUS HNRNPUL1 CREB1 SLC33A1

1.17e-04567689int:CUL5
InteractionTHRAP3 interactions

AKAP8 MYO10 RBM14 EWSR1 RNF40 TAF15 FUS MED12

1.19e-04443688int:THRAP3
InteractionMIR15A interactions

RBM14 FAM98A TAF15 FUS

1.20e-0475684int:MIR15A
InteractionHNRNPK interactions

CIRBP OTX2 DDX17 AKAP8 DVL2 RBM14 EWSR1 TAF15 FUS CREB1 YTHDF2

1.23e-048536811int:HNRNPK
InteractionMIR7-3 interactions

RBM14 FAM98A TAF15 FUS

1.27e-0476684int:MIR7-3
InteractionMIR16-1 interactions

RBM14 FAM98A TAF15 FUS

1.27e-0476684int:MIR16-1
InteractionMIR199A2 interactions

RBM14 FAM98A TAF15 FUS

1.27e-0476684int:MIR199A2
InteractionNCOA6 interactions

GRIP1 SOX9 RBM14 EWSR1 FUS

1.30e-04145685int:NCOA6
InteractionPRPF19 interactions

DVL2 RBM14 RBM5 RNF40 TAF15 KIF5B FUS MED12

1.33e-04450688int:PRPF19
InteractionMIR9-2 interactions

RBM14 FAM98A TAF15 FUS

1.33e-0477684int:MIR9-2
InteractionMIR200A interactions

RBM14 FAM98A TAF15 FUS

1.33e-0477684int:MIR200A
InteractionCCAR2 interactions

FXR2 DVL2 RBM14 RBM5 EWSR1 TAF15 FUS

1.39e-04337687int:CCAR2
InteractionMIR98 interactions

RBM14 FAM98A TAF15 FUS

1.40e-0478684int:MIR98
InteractionHNRNPM interactions

ZEB1 DDX17 FXR2 RBM14 EWSR1 DNAJB7 TAF15 FUS HNRNPUL1 MED12

1.47e-047236810int:HNRNPM
Cytoband17p13.1

FXR2 DVL2 ATP1B2

7.66e-0411869317p13.1
Cytoband22q11.2

IGLV2-14 IGLV2-11 IGLV2-8

8.05e-0412069322q11.2
Cytoband1p13.2

HIPK1 CTTNBP2NL

2.21e-03466921p13.2
GeneFamilyRNA binding motif containing

CIRBP RBMXL3 RBM14 RBM5 EWSR1 TAF15 HNRNPA1L2 FUS

4.82e-08213458725
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RBM5 EWSR1 TAF15 FUS

1.94e-072145489
GeneFamilyEF-hand domain containing|S100 fused type protein family

HRNR FLG2

1.26e-0474521350
GeneFamilyKinesins|Pleckstrin homology domain containing

STARD9 KIF5A KIF5B

2.03e-0446453622
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLV2-14 IGLV2-11 IGLV2-8

1.41e-0389453353
GeneFamilyPDZ domain containing

GRIP1 DVL2 DLG3

6.38e-031524531220
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 EYA1 ATP1B2

1.04e-0518669573cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NEFL OTX2 EBF3 SOBP KIF5A

1.34e-051966950767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.40e-05198695a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-oRG|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.40e-0519869572dc49aa107d0cc6206eb67b577c73e190855125
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-20|World / Primary Cells by Cluster

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.40e-05198695bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial-oRG|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.44e-05199695151bda6821b52cfb4491474892ecb45781522837
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

NEFL BRINP1 KIF5A FUS SYNPR

1.44e-05199695f30e9d3d095a1e12d759debe27540aad32861db6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.47e-0520069549197316231e45f8c9f007f55b036600f7195922
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial-RG|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ECI2 ATP1B2

1.47e-05200695dea7928d6ceb7a347f56c6d0c9c7a56b7a2c0a80
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

MET NEFL EYA1 FOXI3

8.90e-051516948216462e723fec2797387929dde095370947e10a
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIP1 MET MARVELD3 EYA1

9.13e-051526941b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIP1 MET FOXN4 EYA1

1.14e-041616942d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFL SOBP CLSTN2 KIF5A

1.14e-0416169469f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN EYA1 PGC

1.17e-0416269425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN EYA1 PGC

1.17e-041626943dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN EYA1 PGC

1.17e-041626940a7138266054ea5954649c8b61ef93905d56b068
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMBOX1 LORICRIN STARD9 PRIM2

1.25e-0416569476abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFL SOBP CLSTN2 KIF5A

1.25e-0416569402cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFL SOBP CLSTN2 KIF5A

1.25e-041656946d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellTuft-tuft-1|World / Class top

SOX9 NEFL FAM98A ATP1B2

1.34e-041686948ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMGDH PRIM2 MARVELD3 MED12

1.34e-04168694ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

DMGDH EBF3 STARD9 CD300LG

1.54e-041746940f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3|TCGA-Breast / Sample_Type by Project: Shred V9

DMGDH EBF3 STARD9 CD300LG

1.54e-041746947f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCellTCGA-Breast-Solid_Tissue_Normal|TCGA-Breast / Sample_Type by Project: Shred V9

DMGDH EBF3 STARD9 CD300LG

1.54e-04174694e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

GRIP1 MET LPA EYA1

1.54e-04174694a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

DMGDH EBF3 STARD9 CD300LG

1.54e-041746941aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIP1 MET LPA EYA1

1.68e-04178694fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

GRIP1 MET LPA EYA1

1.71e-04179694d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell10x5'-Lung-Lymphocytic_B_plasma-Plasmablasts|Lung / Manually curated celltypes from each tissue

IGLV2-14 IGLV2-11 IGLV2-8 SLC33A1

1.71e-041796943fa75eec3e86fd1797eaa33362257df7f9b2a0bf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH MET BRINP1 CLSTN2

1.79e-041816949d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH MET BRINP1 CLSTN2

1.82e-04182694eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX9 MET CLSTN2 PGC

1.82e-04182694d1a1feef318062f25493355d7beee8e5fb0e4206
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

GRIP1 MET LPA EYA1

1.86e-0418369400a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NEFL NUP98 CLSTN2 KIF5A

1.90e-04184694eac2a9089913f33a961ba11519b53645790f2056
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX9 ZEB1 EBF3 SOBP

1.94e-041856948f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 SOBP PRIM2 FUS

1.98e-04186694de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 SOBP PRIM2 FUS

1.98e-041866940b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

GRIP1 MET SOBP EYA1

2.02e-041876948407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

GRIP1 TCF20 MYO10 PRIM2

2.06e-04188694b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

CIRBP DDX17 HIPK1 FUS

2.11e-041896940e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 ATP1B2

2.15e-0419069478cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7|World / Primary Cells by Cluster

SOX9 MYO10 ECI2 ATP1B2

2.15e-041906948f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 ATP1B2

2.15e-04190694e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte|World / Primary Cells by Cluster

SOX9 MYO10 ECI2 ATP1B2

2.15e-041906947dbfd543398c63cbe1e68b54bcb5e2291f521935
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZEB1 SOBP STARD9 CLSTN2

2.19e-0419169470c067c54084bfb02c29bab085f4defd477194fb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CIRBP SOX9 ZEB1 EBF3

2.24e-04192694d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

DDX17 HIPK1 RBM14 FUS

2.24e-0419269447646d7e4990be85072987f92bf18d52f8da752e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 ATP1B2

2.24e-0419269443beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 ATP1B2

2.28e-04193694b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG-34|World / Primary Cells by Cluster

SOX9 MYO10 ECI2 ATP1B2

2.28e-04193694d55f792eb3db10452347681131e07e041348fd89
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 GAREM2 MYO10 ATP1B2

2.28e-0419369440edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZEB1 CD300LG BRINP1 CTTNBP2NL

2.33e-0419469468004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GRIP1 MET MARVELD3 EYA1

2.33e-041946946b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG|World / Primary Cells by Cluster

SOX9 ZEB1 MYO10 ATP1B2

2.33e-041946943a4bf6a7fac0e5bdbb4bb17041806d06a75974d9
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

SOX9 MET ZEB1 CTTNBP2NL

2.42e-0419669438ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ATP1B2

2.47e-0419769458b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEFL STARD9 KIF5A SYNPR

2.47e-04197694e239caae24f40564a24ad909754f5436f767ccdb
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV2-14 IGLV2-11 DNAJB7 FAM98A

2.52e-041986949a77038e5db0ea757fd7ebcab294785b166ddc12
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 OTX2 MYO10 ATP1B2

2.52e-041986943811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Radial_glial|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 MYO10 ECI2 ATP1B2

2.56e-041996940fee11bd72b27202f8d9fa4daba831ea9c8a61b2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

BRINP1 KIF5A FUS SYNPR

2.61e-04200694e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte|3m / Sample Type, Dataset, Time_group, and Cell type.

SOX9 ZEB1 MYO10 ATP1B2

2.61e-0420069498d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SOX9 MYO10 ECI2 ATP1B2

2.61e-04200694ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 EBF3 STARD9 CLSTN2

2.61e-042006940c25d56292b9e5fefa4521b72635449be1ffd6fe
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A

SOX9 MET ZEB1 DDX17 MYO10 RBM5 TAF15

1.54e-061896874271_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

SOX9 MET ZEB1 MYO10 KIF5B FUS

1.59e-051796864585_DN
Drugpoly(G

CIRBP NUP98 RBM5 FUS HNRNPUL1

2.34e-05114685CID000439502
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A

MET DDX17 MYO10 HIPK1 RBM5 TAF15

2.36e-051926864274_DN
DrugCapsaicin [404-86-4]; Down 200; 13uM; PC3; HT_HG-U133A

MET RBM5 HELZ TAF15 FUS CREB1

2.50e-051946864612_DN
DrugSulfadoxine [2447-57-6]; Down 200; 12.8uM; PC3; HT_HG-U133A

MET HIPK1 RBM5 TAF15 FUS MED12

2.80e-051986865852_DN
Diseaseamyotrophic lateral sclerosis type 6 (implicated_via_orthology)

EWSR1 TAF15 FUS

9.73e-093643DOID:0060198 (implicated_via_orthology)
DiseaseCongenital small ears

GRIP1 OTX2 EYA1 FOXI3

1.92e-0641644C0152423
Diseasefrontotemporal dementia (implicated_via_orthology)

EWSR1 TAF15 FUS

2.11e-0612643DOID:9255 (implicated_via_orthology)
Diseasetriglycerides to total lipids in small VLDL percentage

DMGDH LPA CD300LG LPAL2

7.82e-0658644EFO_0022338
Diseasetriglycerides to total lipids in small LDL percentage

DMGDH LPA CD300LG LPAL2

8.37e-0659644EFO_0022337
Diseasetriglycerides in small VLDL measurement

DMGDH LPA CD300LG LPAL2

9.57e-0661644EFO_0022145
Diseasetriglycerides in small HDL measurement

DMGDH LPA CD300LG LPAL2

1.02e-0562644EFO_0022158
Diseasetriglycerides to total lipids in IDL percentage

DMGDH LPA CD300LG LPAL2

1.09e-0563644EFO_0022329
Diseasetriglycerides to total lipids in medium VLDL percentage

DMGDH LPA CD300LG LPAL2

1.09e-0563644EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

DMGDH LPA CD300LG LPAL2

1.09e-0563644EFO_0022239
Diseasefree cholesterol to total lipids in medium LDL percentage

DMGDH LPA CD300LG LPAL2

1.09e-0563644EFO_0022283
Diseasecholesteryl esters to total lipids in medium VLDL percentage

DMGDH LPA CD300LG LPAL2

1.16e-0564644EFO_0022253
Diseasecholesterol to total lipids in very small VLDL percentage

DMGDH LPA CD300LG LPAL2

1.39e-0567644EFO_0022245
DiseaseMajor Depressive Disorder

SOX9 NEFL AKAP8 DLG3 CREB1 MED12

1.47e-05243646C1269683
Diseasetriglycerides to total lipids in very small VLDL percentage

DMGDH LPA CD300LG LPAL2

1.56e-0569644EFO_0022341
Diseasecholesteryl esters to total lipids in very small VLDL percentage

DMGDH LPA CD300LG LPAL2

1.75e-0571644EFO_0022259
Diseasefree cholesterol to total lipids in large LDL percentage

DMGDH LPA CD300LG LPAL2

2.07e-0574644EFO_0022280
DiseaseUnipolar Depression

SOX9 NEFL AKAP8 DLG3 CREB1 MED12

2.11e-05259646C0041696
Diseasefree cholesterol to total lipids in small VLDL percentage

DMGDH LPA CD300LG LPAL2

2.18e-0575644EFO_0022287
DiseaseClear Cell Sarcoma of Soft Tissue

EWSR1 CREB1

2.77e-054642C0206651
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

EWSR1 TAF15 FUS

3.79e-0530643DOID:332 (implicated_via_orthology)
Diseasesarcoma (is_marker_for)

MET FUS

4.61e-055642DOID:1115 (is_marker_for)
DiseaseExtraskeletal Myxoid Chondrosarcoma

EWSR1 TAF15

4.61e-055642C1275278
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

NEFL KIF5A FUS

4.61e-0532643DOID:332 (is_implicated_in)
Diseasepeeling skin syndrome (is_implicated_in)

CDSN FLG2

6.91e-056642DOID:0060283 (is_implicated_in)
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

TCF20 LPA CD300LG LPAL2

7.57e-05103644EFO_0008595, EFO_0020944
Diseaselipoprotein A measurement, apolipoprotein A 1 measurement

LPA LPAL2

9.66e-057642EFO_0004614, EFO_0006925
Diseasespinal muscular atrophy (implicated_via_orthology)

KIF5A KIF5B

1.65e-049642DOID:12377 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in small VLDL percentage

LPA CD300LG LPAL2

1.67e-0449643EFO_0022256
Diseasetriglycerides to total lipids in medium LDL percentage

LPA CD300LG LPAL2

1.77e-0450643EFO_0022334
Diseasepolyunsaturated fatty acids to total fatty acids percentage

LPA CD300LG LPAL2

1.77e-0450643EFO_0022303
Diseasecholesteryl esters to total lipids in IDL percentage

LPA CD300LG LPAL2

1.77e-0450643EFO_0022247
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

LPA CD300LG LPAL2

1.88e-0451643EFO_0022302
Diseasecholesterol to total lipids in small HDL percentage

LPA CD300LG LPAL2

1.88e-0451643EFO_0022240
Diseasecholesterol to total lipids in small VLDL percentage

LPA CD300LG LPAL2

1.88e-0451643EFO_0022242
Diseasefree cholesterol to total lipids in small LDL percentage

LPA CD300LG LPAL2

2.11e-0453643EFO_0022286
Diseasecholesteryl esters to total lipids in very large VLDL percentage

LPA CD300LG LPAL2

2.11e-0453643EFO_0022258
Diseasecholesterol to total lipids in very large VLDL percentage

LPA CD300LG LPAL2

2.23e-0454643EFO_0022244
Diseasecholesterol to total lipids in large HDL percentage

DMGDH LPA CD300LG

2.36e-0455643EFO_0022234
Diseasetriglycerides in very large VLDL measurement

LPA CD300LG LPAL2

2.49e-0456643EFO_0022325
Diseasetriglycerides to total lipids in medium HDL percentage

LPA CD300LG LPAL2

2.49e-0456643EFO_0022333
Diseasetriglycerides in chylomicrons and extremely large VLDL measurement

LPA CD300LG LPAL2

2.49e-0456643EFO_0022316
Diseasefree cholesterol to total lipids in large HDL percentage

LPA CD300LG LPAL2

2.49e-0456643EFO_0022279
Diseasecholesteryl esters to total lipids in medium HDL percentage

LPA CD300LG LPAL2

2.49e-0456643EFO_0022251
Diseasevascular dementia (is_marker_for)

NEFL LPA

2.52e-0411642DOID:8725 (is_marker_for)
Diseasefree cholesterol to total lipids in medium VLDL percentage

LPA CD300LG LPAL2

2.62e-0457643EFO_0022284
DiseaseAmyotrophic Lateral Sclerosis

EWSR1 TAF15 FUS

2.76e-0458643C0002736
Diseaselow density lipoprotein particle size measurement

LPA CD300LG LPAL2

2.76e-0458643EFO_0008593
Diseaseneurodegenerative disease (implicated_via_orthology)

DVL2 HNRNPA1L2 KIF5A KIF5B

2.83e-04145644DOID:1289 (implicated_via_orthology)
Diseasetriglycerides in VLDL measurement

LPA CD300LG LPAL2

2.90e-0459643EFO_0022326
Diseaseconcentration of chylomicrons and extremely large VLDL particles measurement

LPA CD300LG LPAL2

2.90e-0459643EFO_0022260
Diseasetriglyceride measurement, phospholipid measurement

DMGDH LPA CD300LG LPAL2

2.90e-04146644EFO_0004530, EFO_0004639
Diseasemotor neuron disease (implicated_via_orthology)

KIF5A KIF5B

3.01e-0412642DOID:231 (implicated_via_orthology)
Diseasetriglycerides to total lipids in large HDL percentage

LPA CD300LG LPAL2

3.05e-0460643EFO_0022330
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

LPA CD300LG LPAL2

3.05e-0460643EFO_0021898
Diseasecholesterol to total lipids in IDL percentage

LPA CD300LG LPAL2

3.05e-0460643EFO_0022233
Diseasecholesterol to total lipids in medium HDL percentage

LPA CD300LG LPAL2

3.05e-0460643EFO_0022237
Diseasefree cholesterol in very large VLDL measurement

LPA CD300LG LPAL2

3.20e-0461643EFO_0022274
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

DMGDH LPA CD300LG LPAL2

3.22e-04150644EFO_0004611, EFO_0020947
Diseasetriglycerides to total lipids in very large HDL percentage

LPA CD300LG LPAL2

3.36e-0462643EFO_0022339
Diseasephospholipids in large VLDL measurement

LPA CD300LG LPAL2

3.36e-0462643EFO_0022169
Diseasetotal lipids in chylomicrons and extremely large VLDL measurement

LPA CD300LG LPAL2

3.36e-0462643EFO_0022306
Diseasetotal lipids in very large VLDL measurement

LPA CD300LG LPAL2

3.36e-0462643EFO_0022313
Diseasefree cholesterol in chylomicrons and extremely large VLDL measurement

LPA CD300LG LPAL2

3.36e-0462643EFO_0022263
Diseasephospholipids in very large VLDL measurement

LPA CD300LG LPAL2

3.36e-0462643EFO_0022299
Diseaseautism spectrum disorder (implicated_via_orthology)

MET TCF20 FXR2 BRINP1

3.38e-04152644DOID:0060041 (implicated_via_orthology)
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

LPA CD300LG LPAL2

3.52e-0463643EFO_0022292
Diseasetriglycerides in small LDL measurement

LPA CD300LG LPAL2

3.86e-0465643EFO_0022323
Diseasetotal lipids in very large HDL measurement

LPA CD300LG LPAL2

4.04e-0466643EFO_0022312
Diseasephospholipids in very large HDL measurement

LPA CD300LG LPAL2

4.04e-0466643EFO_0022298
Diseasetriglycerides to phosphoglycerides ratio

LPA CD300LG LPAL2

4.41e-0468643EFO_0022327
Diseasefree cholesterol in large VLDL measurement

LPA CD300LG LPAL2

4.41e-0468643EFO_0022265
Diseasecholesterol in very large HDL measurement

LPA CD300LG LPAL2

4.60e-0469643EFO_0022229
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

LPA LPAL2

4.77e-0415642EFO_0022328
Diseasetriglycerides to total lipids in small HDL percentage

LPA CD300LG LPAL2

5.22e-0472643EFO_0022336
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

LPA LPAL2

6.17e-0417642EFO_0022232
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

LPA CD300LG LPAL2

6.59e-0478643EFO_0022187
Diseasefree cholesterol to total lipids in chylomicrons and extremely large VLDL percentage

LPA LPAL2

9.47e-0421642EFO_0022277
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

LPA LPAL2

9.47e-0421642EFO_0022246
Diseasedocosahexaenoic acid to total fatty acids percentage

LPA LPAL2

9.47e-0421642EFO_0022262
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DMGDH LPA CD300LG LPAL2

9.47e-04200644EFO_0004611, EFO_0020945
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

LPA CD300LG EYA1 LPAL2

1.06e-03206644EFO_0004612, EFO_0020947
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

LPA CD300LG LPAL2

1.17e-0395643EFO_0004529, EFO_0008317, EFO_0008596
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

LPA CD300LG LPAL2

1.20e-0396643EFO_0004530, EFO_0008317, EFO_0008596
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

DMGDH LPA CD300LG LPAL2

1.39e-03222644EFO_0008317, EFO_0020943
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

DMGDH LPA CD300LG LPAL2

1.44e-03224644EFO_0004530, EFO_0008317
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

DMGDH LPA CD300LG LPAL2

1.46e-03225644EFO_0008317, EFO_0020947
Diseasephospholipids:total lipids ratio

DMGDH LPA CD300LG LPAL2

1.51e-03227644EFO_0020946
Diseasebipolar disorder

TCF20 STARD9 DNAJB7 BRINP1 KIF5B ZMIZ1

1.56e-03577646MONDO_0004985
Diseasegamma-glutamyltyrosine measurement

MARVELD3 ZMIZ1

1.57e-0327642EFO_0021144
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

LPA CD300LG LPAL2

1.60e-03106643EFO_0008317, EFO_0008596
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement

LPA CD300LG LPAL2

1.73e-03109643EFO_0004639, EFO_0008317, EFO_0008596
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

LPA CD300LG LPAL2

1.78e-03110643EFO_0008317, EFO_0008596, EFO_0010351
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

LPA CD300LG LPAL2

1.78e-03110643EFO_0008317, EFO_0008591, EFO_0008596
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

LPA CD300LG LPAL2

1.78e-03110643EFO_0004574, EFO_0008317, EFO_0008596
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DMGDH LPA CD300LG LPAL2

1.82e-03239644EFO_0008317, EFO_0020945
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

DMGDH LPA CD300LG LPAL2

1.94e-03243644EFO_0004612, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
GYNQDSYGSSSGYSQ

SYNPR

226

Q8TBG9
SYGSSSGYSQQASLG

SYNPR

231

Q8TBG9
GYASTCNSVGQTAGY

SLC33A1

211

O00400
SASSPGYQSSYQVGI

CTTNBP2NL

441

Q9P2B4
QGYGTGAYDTTTATV

EWSR1

91

Q01844
QLNSGYYVSGSSSGF

RNF40

306

O75150
YYVSGSSSGFQGGQI

RNF40

311

O75150
VNQSYTQGGQFYSSS

BRINP1

676

O60477
NYYGAQNTSVTTGAT

AKAP8

36

O43823
QNTSVTTGATYSYGP

AKAP8

41

O43823
LGSRYSSGYSSAEQV

FAM219B

131

Q5XKK7
ETTYTGGNGFSTSYN

DOP1A

2276

Q5JWR5
GYSQVSYSSGSGSSL

CDSN

111

Q15517
DATNSTAGYSIYGVG

CLSTN2

726

Q9H4D0
LSSYTYGGGSASSQH

DVL2

571

O14641
NQGGYGVSSSSSSYG

HNRNPA1L2

301

Q32P51
SYGQSGGEQQSYSTY

TAF15

6

Q92804
ASQSYSGYGQTTDSS

TAF15

31

Q92804
SGYGQTTDSSYGQNY

TAF15

36

Q92804
TTDSSYGQNYSGYSS

TAF15

41

Q92804
SGYSSYGQSQSGYSQ

TAF15

51

Q92804
SSLASYGNQPSSYGA

RBM14

336

Q96PK6
SSYGAQAASSYGVRA

RBM14

346

Q96PK6
GYNGTIFAYGQTSSG

KIF5B

76

P33176
SQSSGYGQYGSRETS

FLG2

551

Q5D862
SYGQHGSGSSQSSGY

FLG2

921

Q5D862
YRSGQSSYGQHGTGS

FLG2

1146

Q5D862
AYGQNKTAFGTSTTG

NUP98

251

P52948
STSNSTGQRSSYYSP

FOXI3

371

A8MTJ6
SSSLHATRTYGGSYG

FXR2

416

P51116
TQSYIGSSRGSTIYT

HIPK1

1181

Q86Z02
QSYSGYSQSTDTSGY

FUS

36

P35637
YSQSTDTSGYGQSSY

FUS

41

P35637
DTSGYGQSSYSSYGQ

FUS

46

P35637
GQSSYSSYGQSQNTG

FUS

51

P35637
SSYGQSQNTGYGTQS

FUS

56

P35637
SQNTGYGTQSTPQGY

FUS

61

P35637
YGSSQSSQSSYGQQS

FUS

81

P35637
GSYGSSSQSSSYGQP

FUS

111

P35637
SSQSSSYGQPQSGSY

FUS

116

P35637
SGIGDSTHYGYSTGQ

ATP1B2

161

P14415
SYGGSSYGNSTNNVP

HMBOX1

66

Q6NT76
GSSFTTSSGIYTGNN

EYA1

186

Q99502
SGQHNSYSGQSSSYG

HRNR

166

Q86YZ3
GTYNSSGAYRFSSEG

MYO10

1126

Q9HD67
SGGSGSGYVSSQQVT

LORICRIN

201

P23490
TPSSSYGLQTSQGYT

MED12

1931

Q93074
LSLGSSSGSNGFYSY

HELZ

1926

P42694
ASSYLGSTGYVGSSR

ODAD1

606

Q96M63
TQSQSGEGGSVDYSY

RBM5

346

P52756
SYTGQDYSTQGNVGK

PRIM2

256

P49643
SSYDTGYTSQGSLGH

DNAJB7

151

Q7Z6W7
TGGEGAYLYSSNLQS

DNAAF9

541

Q5TEA3
GDGQSYRGTYSTTVT

LPA

31

P08519
NGQSYRGTYSTTVTG

LPA

146

P08519
GQSYRGTYSTTVTGR

LPA

261

P08519
YHGNGQSYRGTYSTT

LPA

371

P08519
HGNGQSYRGTYSTTV

LPA

486

P08519
GNGQSYRGTYSTTVT

LPA

601

P08519
NGQSYRGTYSTTVTG

LPA

716

P08519
GQSYRGTYSTTVTGR

LPA

831

P08519
GDGQSYRGSFSTTVT

LPA

1171

P08519
YGGYSSQTLPSQAGA

DLG3

51

Q92796
YQTSSGQYIAITQGG

CREB1

161

P16220
VVGNTTSGSYSYSIQ

DMGDH

796

Q9UI17
SSVSYSSTGGYTGIT

MARVELD3

216

Q96A59
AGYNGTIFAYGQTSS

KIF5A

76

Q12840
ITVLTGNGDYYSSGN

ECI2

186

O75521
TAQEYGAGTYGASST

DDX17

651

Q92841
SNYNTVSTSMNGYGS

EBF3

481

Q9H4W6
TSYGTQGTSFQASGY

GRIP1

816

Q9Y3R0
CTGTSSDVGGYNYVS

IGLV2-11

41

P01706
DYGSYSGNTQGGTST

HNRNPUL1

841

Q9BUJ2
CTGTSSDVGGYNYVS

IGLV2-14

41

P01704
QASGYSQGYAGSTSY

OTX2

181

P32243
ASGTSSSSQYLGAQG

FOXN4

496

Q96NZ1
SSLSYYSSGLQDGAG

GAREM2

521

Q75VX8
SNGHGTTQYSTFSYV

MET

641

P08581
SNGQSYRGTYFTTVT

LPAL2

31

Q16609
CTGTSSDVGGYNYVS

IGLV2-8

41

P01709
FQTSSSYTGSGYQGG

FAM98A

426

Q8NCA5
GQVTYTGSYGISSTA

SOX9

311

P48436
NGSLSSGMTSGYNSS

STARD9

4401

Q9P2P6
GTSQYGHERTSQYTG

CD300LG

186

Q6UXG3
SQSGGYSDRSSGGSY

CIRBP

146

Q14011
STYSTNGQTFSLQYG

PGC

121

P20142
YSGGRSSSSNGYSRS

RBMXL3

366

Q8N7X1
YNISTGYSGLATGNG

SOBP

96

A7XYQ1
GSGGSTSDYVSQSYS

USP47

161

Q96K76
SGQSYDGSYNVNAGS

TCF20

256

Q9UGU0
SSSRNTQGYLYTAEG

ZEB1

711

P37275
NGSQSSTYRGTYEQD

ZNF396

221

Q96N95
GQSTQSSGYSSNYAY

YTHDF2

141

Q9Y5A9
TFSGSSYSNYSQGNV

ZMIZ1

481

Q9ULJ6
GSITSGYSQSSQVFG

NEFL

406

P07196
GYSQSSQVFGRSAYG

NEFL

411

P07196