Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity

NANOG NANOGP8 NANOGP1

6.03e-11463GO:0001010
GeneOntologyMolecularFunctionlysine-acetylated histone binding

NANOG NANOGP8 NANOGP1

6.10e-083063GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

NANOG NANOGP8 NANOGP1

6.75e-083163GO:0140033
GeneOntologyMolecularFunctionmodification-dependent protein binding

NANOG NANOGP8 NANOGP1

2.12e-0520663GO:0140030
GeneOntologyMolecularFunctionhistone binding

NANOG NANOGP8 NANOGP1

4.49e-0526563GO:0042393
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

NANOG NANOGP8 NANOGP1

7.87e-0532063GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

NANOG NANOGP8 NANOGP1

8.31e-0532663GO:0001217
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

NANOG NANOGP8 NANOGP1

4.12e-0456063GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

NANOG NANOGP8 NANOGP1

4.25e-0456663GO:0001216
GeneOntologyMolecularFunctionchromatin binding

NANOG NANOGP8 NANOGP1

9.29e-0473963GO:0003682
GeneOntologyMolecularFunctiontranscription factor binding

NANOG NANOGP8 NANOGP1

9.81e-0475363GO:0008134
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NANOG NANOGP8 NANOGP1

3.42e-03116063GO:0030674
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NANOG NANOGP8 NANOGP1

4.18e-03124463GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NANOG NANOGP8 NANOGP1

4.45e-03127163GO:0000987
GeneOntologyMolecularFunctionmolecular adaptor activity

NANOG NANOGP8 NANOGP1

5.35e-03135663GO:0060090
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NANOG NANOGP8 NANOGP1

6.00e-03141263GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NANOG NANOGP8 NANOGP1

6.58e-03145963GO:0000977
GeneOntologyBiologicalProcessnegative regulation of endodermal cell fate specification

NANOG NANOGP8 NANOGP1

2.74e-11453GO:0042664
GeneOntologyBiologicalProcessregulation of endodermal cell fate specification

NANOG NANOGP8 NANOGP1

6.84e-11553GO:0042663
GeneOntologyBiologicalProcessnegative regulation of endodermal cell differentiation

NANOG NANOGP8 NANOGP1

1.37e-10653GO:1903225
GeneOntologyBiologicalProcessnegative regulation of cell fate specification

NANOG NANOGP8 NANOGP1

3.83e-10853GO:0009996
GeneOntologyBiologicalProcessregulation of endodermal cell differentiation

NANOG NANOGP8 NANOGP1

8.20e-101053GO:1903224
GeneOntologyBiologicalProcessendodermal cell fate specification

NANOG NANOGP8 NANOGP1

1.13e-091153GO:0001714
GeneOntologyBiologicalProcesscell dedifferentiation

NANOG NANOGP8 NANOGP1

3.11e-091553GO:0043697
GeneOntologyBiologicalProcessdedifferentiation

NANOG NANOGP8 NANOGP1

3.11e-091553GO:0043696
GeneOntologyBiologicalProcessnegative regulation of cell fate commitment

NANOG NANOGP8 NANOGP1

4.65e-091753GO:0010454
GeneOntologyBiologicalProcessendodermal cell fate commitment

NANOG NANOGP8 NANOGP1

5.57e-091853GO:0001711
GeneOntologyBiologicalProcessregulation of stem cell division

NANOG NANOGP8 NANOGP1

5.57e-091853GO:2000035
GeneOntologyBiologicalProcessmesodermal cell fate commitment

NANOG NANOGP8 NANOGP1

1.21e-082353GO:0001710
GeneOntologyBiologicalProcessregulation of cell fate specification

NANOG NANOGP8 NANOGP1

2.49e-082953GO:0042659
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

NANOG NANOGP8 NANOGP1

3.72e-083353GO:2000737
GeneOntologyBiologicalProcessmesodermal cell differentiation

NANOG NANOGP8 NANOGP1

4.47e-083553GO:0048333
GeneOntologyBiologicalProcesscell fate commitment involved in formation of primary germ layer

NANOG NANOGP8 NANOGP1

5.30e-083753GO:0060795
GeneOntologyBiologicalProcessendodermal cell differentiation

NANOG NANOGP8 NANOGP1

5.75e-083853GO:0035987
GeneOntologyBiologicalProcessendoderm formation

NANOG NANOGP8 NANOGP1

1.26e-074953GO:0001706
GeneOntologyBiologicalProcessstem cell division

NANOG NANOGP8 NANOGP1

1.26e-074953GO:0017145
GeneOntologyBiologicalProcessregulation of cell fate commitment

NANOG NANOGP8 NANOGP1

1.60e-075353GO:0010453
GeneOntologyBiologicalProcessstem cell differentiation

NANOG NANOGP8 SEMA5A NANOGP1

2.35e-0730654GO:0048863
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

NANOG NANOGP8 NANOGP1

5.59e-078053GO:0030514
GeneOntologyBiologicalProcessmesoderm formation

NANOG NANOGP8 NANOGP1

6.02e-078253GO:0001707
GeneOntologyBiologicalProcessmesoderm morphogenesis

NANOG NANOGP8 NANOGP1

6.96e-078653GO:0048332
GeneOntologyBiologicalProcessnegative regulation of developmental process

ADGRB3 NANOG NANOGP8 SEMA5A NANOGP1

7.18e-07122055GO:0051093
GeneOntologyBiologicalProcessendoderm development

NANOG NANOGP8 NANOGP1

7.46e-078853GO:0007492
GeneOntologyBiologicalProcessregulation of stem cell differentiation

NANOG NANOGP8 NANOGP1

1.07e-069953GO:2000736
GeneOntologyBiologicalProcesssomatic stem cell population maintenance

NANOG NANOGP8 NANOGP1

1.39e-0610853GO:0035019
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

ADGRB3 NANOG NANOGP8 SEMA5A NANOGP1

1.91e-06148355GO:0048646
GeneOntologyBiologicalProcesscell fate specification

NANOG NANOGP8 NANOGP1

2.05e-0612353GO:0001708
GeneOntologyBiologicalProcessformation of primary germ layer

NANOG NANOGP8 NANOGP1

2.10e-0612453GO:0001704
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

NANOG NANOGP8 NANOGP1

2.48e-0613153GO:0030510
GeneOntologyBiologicalProcessresponse to retinoic acid

NANOG NANOGP8 NANOGP1

2.48e-0613153GO:0032526
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

NANOG NANOGP8 NANOGP1

3.73e-0615053GO:0090288
GeneOntologyBiologicalProcesspositive regulation of mitotic cell cycle

NANOG NANOGP8 NANOGP1

4.12e-0615553GO:0045931
GeneOntologyBiologicalProcessmesoderm development

NANOG NANOGP8 NANOGP1

4.28e-0615753GO:0007498
GeneOntologyBiologicalProcesstissue morphogenesis

NANOG NANOGP8 SEMA5A NANOGP1

8.42e-0675054GO:0048729
GeneOntologyBiologicalProcessBMP signaling pathway

NANOG NANOGP8 NANOGP1

8.46e-0619753GO:0030509
GeneOntologyBiologicalProcessregulation of cell division

NANOG NANOGP8 NANOGP1

8.99e-0620153GO:0051302
GeneOntologyBiologicalProcessgastrulation

NANOG NANOGP8 NANOGP1

1.05e-0521253GO:0007369
GeneOntologyBiologicalProcessresponse to BMP

NANOG NANOGP8 NANOGP1

1.10e-0521553GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

NANOG NANOGP8 NANOGP1

1.10e-0521553GO:0071773
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

NANOG NANOGP8 NANOGP1

1.15e-0521853GO:0090101
GeneOntologyBiologicalProcessstem cell population maintenance

NANOG NANOGP8 NANOGP1

1.47e-0523753GO:0019827
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

NANOG NANOGP8 SEMA5A NANOGP1

1.55e-0587554GO:0045596
GeneOntologyBiologicalProcessmaintenance of cell number

NANOG NANOGP8 NANOGP1

1.57e-0524253GO:0098727
GeneOntologyBiologicalProcesscell fate commitment

NANOG NANOGP8 NANOGP1

4.26e-0533853GO:0045165
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

NANOG NANOGP8 NANOGP1

4.60e-0534753GO:0090092
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

NANOG NANOGP8 SEMA5A NANOGP1

5.26e-05119054GO:0008284
GeneOntologyBiologicalProcesspositive regulation of cell cycle

NANOG NANOGP8 NANOGP1

7.41e-0540753GO:0045787
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

NANOG NANOGP8 NANOGP1

7.68e-0541253GO:0090287
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

NANOG NANOGP8 NANOGP1

9.66e-0544553GO:0141091
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

NANOG NANOGP8 NANOGP1

1.22e-0448253GO:0007178
GeneOntologyBiologicalProcessregulation of mitotic cell cycle

NANOG NANOGP8 NANOGP1

2.28e-0459453GO:0007346
GeneOntologyBiologicalProcesscell division

NANOG NANOGP8 NANOGP1

3.65e-0469753GO:0051301
GeneOntologyBiologicalProcessembryonic morphogenesis

NANOG NANOGP8 NANOGP1

3.90e-0471353GO:0048598
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

NANOG NANOGP8 NANOGP1

6.55e-0485053GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

NANOG NANOGP8 NANOGP1

7.33e-0488353GO:0070848
GeneOntologyBiologicalProcessmitotic cell cycle

NANOG NANOGP8 NANOGP1

1.10e-03101453GO:0000278
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

NANOG NANOGP8 NANOGP1

1.23e-03105353GO:0000122
GeneOntologyBiologicalProcessresponse to lipid

NANOG NANOGP8 NANOGP1

1.49e-03112653GO:0033993
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

NANOG NANOGP8 NANOGP1

1.74e-03118653GO:0007167
GeneOntologyBiologicalProcessregulation of cell cycle

NANOG NANOGP8 NANOGP1

2.05e-03125653GO:0051726
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

NANOG NANOGP8 NANOGP1

2.75e-03139053GO:0045944
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NANOG NANOGP8 NANOGP1

2.81e-03139953GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NANOG NANOGP8 NANOGP1

2.89e-03141353GO:1902679
GeneOntologyBiologicalProcessembryo development

NANOG NANOGP8 NANOGP1

3.03e-03143753GO:0009790
GeneOntologyBiologicalProcesspositive regulation of nervous system development

ADGRB3 SEMA5A

3.93e-0341852GO:0051962
GeneOntologyBiologicalProcessregulation of angiogenesis

ADGRB3 SEMA5A

3.97e-0342052GO:0045765
GeneOntologyBiologicalProcessregulation of vasculature development

ADGRB3 SEMA5A

4.16e-0343052GO:1901342
GeneOntologyBiologicalProcessregulation of neuron projection development

ADGRB3 SEMA5A

8.28e-0361252GO:0010975
GeneOntologyBiologicalProcesscellular component disassembly

ADGRB3 SEMA5A

8.41e-0361752GO:0022411
GeneOntologyBiologicalProcessregulation of nervous system development

ADGRB3 SEMA5A

8.63e-0362552GO:0051960
GeneOntologyCellularComponentcondensed chromosome

NANOG NANOGP8 NANOGP1

3.07e-0530753GO:0000793
GeneOntologyCellularComponentchromatin

NANOG NANOGP8 NANOGP1

3.18e-03148053GO:0000785
MousePhenoabsent primitive endoderm

NANOG NANOGP8 NANOGP1

1.84e-09953MP:0011185
MousePhenoabsent extraembryonic ectoderm

NANOG NANOGP8 NANOGP1

9.98e-091553MP:0002583
MousePhenoabsent embryonic epiblast

NANOG NANOGP8 NANOGP1

1.23e-081653MP:0011184
MousePhenoabnormal primitive endoderm morphology

NANOG NANOGP8 NANOGP1

4.44e-082453MP:0011183
MousePhenoabnormal inner cell mass apoptosis

NANOG NANOGP8 NANOGP1

9.85e-083153MP:0010380
MousePhenoabnormal extraembryonic ectoderm morphology

NANOG NANOGP8 NANOGP1

9.85e-083153MP:0010736
MousePhenodisorganized extraembryonic tissue

NANOG NANOGP8 NANOGP1

1.43e-073553MP:0002582
MousePhenoabnormal embryonic epiblast morphology

NANOG NANOGP8 NANOGP1

2.92e-069453MP:0003886
MousePhenoabnormal bilaminar embryonic disk morphology

NANOG NANOGP8 NANOGP1

3.73e-0610253MP:0012103
MousePhenoabnormal inner cell mass morphology

NANOG NANOGP8 NANOGP1

5.08e-0611353MP:0002718
MousePhenoabnormal embryonic tissue cell apoptosis

NANOG NANOGP8 NANOGP1

2.06e-0518053MP:0013503
MousePhenoabnormal blastocyst morphology

NANOG NANOGP8 NANOGP1

6.12e-0525953MP:0004957
MousePhenoabnormal preimplantation embryo morphology

NANOG NANOGP8 NANOGP1

7.97e-0528353MP:0014137
MousePhenoabnormal embryonic tissue physiology

NANOG NANOGP8 NANOGP1

9.20e-0529753MP:0008932
MousePhenoembryonic lethality between implantation and somite formation, complete penetrance

NANOG NANOGP8 NANOGP1

1.06e-0431153MP:0011096
MousePhenoembryonic lethality between implantation and somite formation

NANOG NANOGP8 NANOGP1

1.38e-0434053MP:0006205
MousePhenoembryonic lethality between implantation and placentation, complete penetrance

NANOG NANOGP8 NANOGP1

4.46e-0450653MP:0011095
MousePhenoembryonic lethality between implantation and placentation

NANOG NANOGP8 NANOGP1

6.18e-0456553MP:0009850
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

NANOG NANOGP8 NANOGP1

1.54e-0377253MP:0014259
MousePhenoembryonic lethality prior to tooth bud stage, complete penetrance

NANOG NANOGP8 NANOGP1

1.58e-0377953MP:0014257
MousePhenoabnormal extraembryonic tissue morphology

NANOG NANOGP8 NANOGP1

2.47e-0390853MP:0002086
MousePhenoabnormal embryonic tissue morphology

NANOG NANOGP8 NANOGP1

4.49e-03111653MP:0002085
MousePhenoembryonic lethality prior to organogenesis

NANOG NANOGP8 NANOGP1

5.58e-03120453MP:0013292
MousePhenoabnormal apoptosis

NANOG NANOGP8 NANOGP1

7.79e-03135353MP:0001648
MousePhenoabnormal programmed cell death

NANOG NANOGP8 NANOGP1

7.90e-03136053MP:0014355
MousePhenoembryonic lethality prior to tooth bud stage

NANOG NANOGP8 NANOGP1

8.29e-03138353MP:0013293
DomainHomeobox

NANOG NANOGP8 NANOGP1

1.91e-0523453PF00046
DomainHOMEOBOX_1

NANOG NANOGP8 NANOGP1

1.96e-0523653PS00027
DomainHOX

NANOG NANOGP8 NANOGP1

1.98e-0523753SM00389
DomainHomeobox_dom

NANOG NANOGP8 NANOGP1

2.03e-0523953IPR001356
DomainHOMEOBOX_2

NANOG NANOGP8 NANOGP1

2.03e-0523953PS50071
DomainTSP_1

ADGRB3 SEMA5A

1.11e-046352PF00090
DomainTSP1_rpt

ADGRB3 SEMA5A

1.18e-046552IPR000884
DomainTSP1

ADGRB3 SEMA5A

1.18e-046552PS50092
DomainTSP1

ADGRB3 SEMA5A

1.18e-046552SM00209
DomainHomeodomain-like

NANOG NANOGP8

3.04e-0333252IPR009057
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

NANOG NANOGP8 NANOGP1

3.53e-0610153MM15829
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

NANOG NANOGP8 NANOGP1

9.34e-0530153MM15983
Pubmed

Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236325825768
Pubmed

Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation.

NANOG NANOGP8 NANOGP1

2.85e-1236331891567
Pubmed

Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236323200040
Pubmed

Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst.

NANOG NANOGP8 NANOGP1

2.85e-1236325753417
Pubmed

Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236325410303
Pubmed

Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.

NANOG NANOGP8 NANOGP1

2.85e-1236324929238
Pubmed

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

NANOG NANOGP8 NANOGP1

2.85e-1236319447925
Pubmed

Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.

NANOG NANOGP8 NANOGP1

2.85e-1236326975336
Pubmed

Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

NANOG NANOGP8 NANOGP1

2.85e-1236323329853
Pubmed

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.

NANOG NANOGP8 NANOGP1

2.85e-1236330814124
Pubmed

Nanog and transcriptional networks in embryonic stem cell pluripotency.

NANOG NANOGP8 NANOGP1

2.85e-1236317211451
Pubmed

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.

NANOG NANOGP8 NANOGP1

2.85e-1236323770853
Pubmed

Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.

NANOG NANOGP8 NANOGP1

2.85e-1236314728807
Pubmed

Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.

NANOG NANOGP8 NANOGP1

2.85e-1236330837263
Pubmed

The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.

NANOG NANOGP8 NANOGP1

2.85e-1236315502159
Pubmed

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.

NANOG NANOGP8 NANOGP1

2.85e-1236326751055
Pubmed

A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.

NANOG NANOGP8 NANOGP1

2.85e-1236320539761
Pubmed

Isolation and characterization of the murine Nanog gene promoter.

NANOG NANOGP8 NANOGP1

2.85e-1236315916719
Pubmed

Nanog induces hyperplasia without initiating tumors.

NANOG NANOGP8 NANOGP1

2.85e-1236325173648
Pubmed

Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.

NANOG NANOGP8 NANOGP1

2.85e-1236327939294
Pubmed

Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236317352742
Pubmed

Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment.

NANOG NANOGP8 NANOGP1

2.85e-1236333334884
Pubmed

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236330846691
Pubmed

NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation.

NANOG NANOGP8 NANOGP1

2.85e-1236321499299
Pubmed

Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.

NANOG NANOGP8 NANOGP1

2.85e-1236320574542
Pubmed

lincRNAs act in the circuitry controlling pluripotency and differentiation.

NANOG NANOGP8 NANOGP1

2.85e-1236321874018
Pubmed

Generation of germline-competent induced pluripotent stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236317554338
Pubmed

Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.

NANOG NANOGP8 NANOGP1

2.85e-1236323054952
Pubmed

Multiple phases in regulation of Nanog expression during pre-implantation development.

NANOG NANOGP8 NANOGP1

2.85e-1236326660234
Pubmed

Nanog retrotransposed genes with functionally conserved open reading frames.

NANOG NANOGP8 NANOGP1

2.85e-1236316845474
Pubmed

Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.

NANOG NANOGP8 NANOGP1

2.85e-1236321194951
Pubmed

Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self-renewal.

NANOG NANOGP8 NANOGP1

2.85e-1236333107035
Pubmed

OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

NANOG NANOGP8 NANOGP1

2.85e-1236323178592
Pubmed

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.

NANOG NANOGP8 NANOGP1

2.85e-1236325005472
Pubmed

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

NANOG NANOGP8 NANOGP1

2.85e-1236318584034
Pubmed

Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification.

NANOG NANOGP8 NANOGP1

2.85e-1236324681518
Pubmed

Nanog-independent reprogramming to iPSCs with canonical factors.

NANOG NANOGP8 NANOGP1

2.85e-1236324527385
Pubmed

Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236321969378
Pubmed

Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.

NANOG NANOGP8 NANOGP1

2.85e-1236316773043
Pubmed

Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236318086680
Pubmed

The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.

NANOG NANOGP8 NANOGP1

2.85e-1236320661723
Pubmed

NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.

NANOG NANOGP8 NANOGP1

2.85e-1236329245050
Pubmed

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

NANOG NANOGP8 NANOGP1

2.85e-1236323665121
Pubmed

Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.

NANOG NANOGP8 NANOGP1

2.85e-1236317360937
Pubmed

Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.

NANOG NANOGP8 NANOGP1

2.85e-1236326733157
Pubmed

Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.

NANOG NANOGP8 NANOGP1

2.85e-1236322337995
Pubmed

Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.

NANOG NANOGP8 NANOGP1

2.85e-1236322388986
Pubmed

Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236321187909
Pubmed

NANOG changes in mouse kidneys with age.

NANOG NANOGP8 NANOGP1

2.85e-1236316313224
Pubmed

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.

NANOG NANOGP8 NANOGP1

2.85e-1236318177668
Pubmed

H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate.

NANOG NANOGP8 NANOGP1

2.85e-1236335976266
Pubmed

Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.

NANOG NANOGP8 NANOGP1

2.85e-1236326549484
Pubmed

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.

NANOG NANOGP8 NANOGP1

2.85e-1236323071603
Pubmed

Nanog promotes transfer of pluripotency after cell fusion.

NANOG NANOGP8 NANOGP1

2.85e-1236316791199
Pubmed

Functional analysis of two Sp1/Sp3 binding sites in murine Nanog gene promoter.

NANOG NANOGP8 NANOGP1

2.85e-1236316541131
Pubmed

Expression of Nanog gene promotes NIH3T3 cell proliferation.

NANOG NANOGP8 NANOGP1

2.85e-1236316259959
Pubmed

Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.

NANOG NANOGP8 NANOGP1

2.85e-1236322142851
Pubmed

Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.

NANOG NANOGP8 NANOGP1

2.85e-1236316501172
Pubmed

The pluripotency rheostat Nanog functions as a dimer.

NANOG NANOGP8 NANOGP1

2.85e-1236318290762
Pubmed

NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.

NANOG NANOGP8 NANOGP1

2.85e-1236324462001
Pubmed

Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6.

NANOG NANOGP8 NANOGP1

2.85e-1236333665763
Pubmed

A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236312609610
Pubmed

Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.

NANOG NANOGP8 NANOGP1

2.85e-1236323333380
Pubmed

A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal.

NANOG NANOGP8 NANOGP1

2.85e-1236316790525
Pubmed

Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.

NANOG NANOGP8 NANOGP1

2.85e-1236322172669
Pubmed

Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236318024963
Pubmed

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236319582141
Pubmed

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236327125671
Pubmed

Identification of genes regulated by nanog which is involved in ES cells pluripotency and early differentiation.

NANOG NANOGP8 NANOGP1

2.85e-1236318442017
Pubmed

Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.

NANOG NANOGP8 NANOGP1

2.85e-1236324227785
Pubmed

NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.

NANOG NANOGP8 NANOGP1

2.85e-1236321119109
Pubmed

Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236332145514
Pubmed

Nanog dynamics in single embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236326760119
Pubmed

Nanog is the gateway to the pluripotent ground state.

NANOG NANOGP8 NANOGP1

2.85e-1236319703398
Pubmed

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.

NANOG NANOGP8 NANOGP1

2.85e-1236322028025
Pubmed

Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236317204467
Pubmed

Nanog safeguards pluripotency and mediates germline development.

NANOG NANOGP8 NANOGP1

2.85e-1236318097409
Pubmed

Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.

NANOG NANOGP8 NANOGP1

2.85e-1236328457890
Pubmed

CrxOS maintains the self-renewal capacity of murine embryonic stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236319800316
Pubmed

Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.

NANOG NANOGP8 NANOGP1

2.85e-1236328636920
Pubmed

Requirement of Nanog dimerization for stem cell self-renewal and pluripotency.

NANOG NANOGP8 NANOGP1

2.85e-1236318436640
Pubmed

Nanog is dispensable for the generation of induced pluripotent stem cells.

NANOG NANOGP8 NANOGP1

2.85e-1236324461999
Pubmed

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.

NANOG NANOGP8 NANOGP1

2.85e-1236323103910
Pubmed

Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.

NANOG NANOGP8 NANOGP1

2.85e-1236315494369
Pubmed

The C-terminal pentapeptide of Nanog tryptophan repeat domain interacts with Nac1 and regulates stem cell proliferation but not pluripotency.

NANOG NANOGP8 NANOGP1

1.14e-1146319366700
Pubmed

The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells.

NANOG NANOGP8 NANOGP1

1.14e-1146325743411
Pubmed

The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

1.14e-1146331262352
Pubmed

Prion protein expression regulates embryonic stem cell pluripotency and differentiation.

NANOG NANOGP8 NANOGP1

1.14e-1146321483752
Pubmed

Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation.

NANOG NANOGP8 NANOGP1

1.14e-1146316166633
Pubmed

Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.

NANOG NANOGP8 NANOGP1

1.14e-1146328093523
Pubmed

CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog.

NANOG NANOGP8 NANOGP1

1.14e-1146322315219
Pubmed

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog.

NANOG NANOGP8 NANOGP1

1.14e-1146321304588
Pubmed

Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal.

NANOG NANOGP8 NANOGP1

1.14e-1146316894029
Pubmed

TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues.

NANOG NANOGP8 NANOGP1

1.14e-1146333058869
Pubmed

GATA-1 directly regulates Nanog in mouse embryonic stem cells.

NANOG NANOGP8 NANOGP1

1.14e-1146326296469
Pubmed

Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors.

NANOG NANOGP8 NANOGP1

1.14e-1146317518637
Pubmed

Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells.

NANOG NANOGP8 NANOGP1

1.14e-1146321810410
Pubmed

Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells.

NANOG NANOGP8 NANOGP1

1.14e-1146321490431
Pubmed

Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors.

NANOG NANOGP8 NANOGP1

1.14e-1146322787153
Pubmed

Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression.

NANOG NANOGP8 NANOGP1

1.14e-1146320071344
CytobandEnsembl 112 genes in cytogenetic band chr12p13

NANOG NANOGP1

8.66e-0435362chr12p13
GeneFamilyNKL subclass homeoboxes and pseudogenes

NANOG NANOGP8 NANOGP1

4.84e-076753519
CoexpressionTESAR_ALK_AND_JAK_TARGETS_MOUSE_ES_D4_DN

NANOG NANOGP8 NANOGP1

7.99e-101063MM741
CoexpressionMIKKELSEN_PLURIPOTENT_STATE_UP

NANOG NANOGP8 NANOGP1

2.42e-091463MM810
CoexpressionPASINI_SUZ12_TARGETS_UP

NANOG NANOGP8 NANOGP1

2.10e-0612563MM1065
CoexpressionRAO_BOUND_BY_SALL4

NANOG NANOGP8 NANOGP1

1.62e-0524763MM1081
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

NANOG NANOGP8 NANOGP1

2.04e-0526763MM984
CoexpressionBOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE

CLUHP3 SEMA5A

4.81e-0415062M2526
CoexpressionDESCARTES_FETAL_LIVER_STELLATE_CELLS

ADGRB3 SEMA5A

5.47e-0416062M40233
CoexpressionGSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_UP

ADGRB3 NANOG

8.26e-0419762M7264
CoexpressionAtlasratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

CLUHP3 NANOG NANOGP8 NANOGP1

2.40e-0576864ratio_SC_vs_MESO_2500_K3
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#5

NANOG NANOGP8 NANOGP1

2.51e-0523263Arv_SC-hpx_blastocyst_500_K5
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#1

NANOG NANOGP8 NANOGP1

2.51e-0523263Arv_SC-H9hpx_500_K1
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000

NANOG NANOGP8 SEMA5A NANOGP1

6.30e-0598164PCBC_DE_1000
CoexpressionAtlasratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500_k-means-cluster#2

NANOG NANOGP8 NANOGP1

6.74e-0532363ratio_SC_vs_ECTO_500_K2
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_500_k-means-cluster#5

NANOG NANOGP8 NANOGP1

9.77e-0536663ratio_SC_vs_EB_500_K5
CoexpressionAtlasratio_StemCell-derived-from_CD34-iPSC_vs_StemCell-fibro_top-relative-expression-ranked_2500_k-means-cluster#4

CLUHP3 NANOGP8 NANOGP1

2.02e-0446863ratio_SC-cbCD34_vs_SC-fibro_2500_K4
CoexpressionAtlasratio_EmbryoidBody-derived-from_CD34-iPSC_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#2

CLUHP3 NANOGP8 NANOGP1

2.25e-0448563ratio_EB-cbCD34_vs_EB-fibro_2500_K2
CoexpressionAtlasratio_StemCell-blastocyst_vs_StemCell-fibro_top-relative-expression-ranked_2500_k-means-cluster#1

CLUHP3 NANOGP8 NANOGP1

2.26e-0448663ratio_SC-blastocyst_vs_SC-fibro_2500_K1
CoexpressionAtlasratio_EmbryoidBody-derived-from_CD34-iPSC_vs_EmbryoidBody-blastocyst_top-relative-expression-ranked_2500_k-means-cluster#3

CLUHP3 NANOGP8 NANOGP1

2.26e-0448663ratio_EB-cbCD34_vs_EB-blastocyst_2500_K3
CoexpressionAtlasratio_StemCell-fibro_vs_StemCell-blastocyst_top-relative-expression-ranked_2500_k-means-cluster#1

CLUHP3 NANOGP8 NANOGP1

2.32e-0449063ratio_SC-fibro_vs_SC-blastocyst_2500_K1
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500

NANOG NANOGP8 NANOGP1

2.35e-0449263Arv_SC-H9hpx_500
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

NANOG NANOGP8 NANOGP1

2.35e-0449263Arv_SC-hpx_blastocyst_500
CoexpressionAtlasratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500

NANOG NANOGP8 NANOGP1

2.35e-0449263PCBC_ratio_SC_vs_ECTO_500
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_500

NANOG NANOGP8 NANOGP1

2.38e-0449463PCBC_ratio_SC_vs_EB_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_500

NANOG NANOGP8 NANOGP1

2.38e-0449463PCBC_SC_CD34+_500
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#5

NANOG NANOGP8 NANOGP1

2.54e-0450563Arv_SC-H9hpx_1000_K5
CoexpressionAtlasratio_EmbryoidBody-fibro_vs_EmbryoidBody-derived-from_CD34-iPSC_top-relative-expression-ranked_2500_k-means-cluster#2

CLUHP3 NANOGP8 NANOGP1

2.59e-0450963ratio_EB-fibro_vs_EB-cbCD34_2500_K2
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#3

NANOG NANOGP8 NANOGP1

2.61e-0451063Arv_SC-hpx_blastocyst_1000_K3
CoexpressionAtlasratio_StemCell-blastocyst_vs_cbCD34_top-relative-expression-ranked_2500_k-means-cluster#1

CLUHP3 NANOGP8 NANOGP1

2.69e-0451563ratio_SC-blastocyst_vs_cbCD34_2500_K1
CoexpressionAtlasratio_EmbryoidBody-fibro_vs_EmbryoidBody-blastocyst_top-relative-expression-ranked_2500_k-means-cluster#1

CLUHP3 NANOGP8 NANOGP1

2.73e-0451863ratio_EB-fibro_vs_EB-blastocyst_2500_K1
CoexpressionAtlasratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#1

NANOG NANOGP8 NANOGP1

2.81e-0452363ratio_SC_vs_ECTO_1000_K1
CoexpressionAtlasratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5

NANOG NANOGP8 NANOGP1

3.09e-0454063ratio_SC_vs_MESO_1000_K5
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2

NANOG NANOGP8 NANOGP1

3.33e-0455463Arv_SC_fibroblast_1000_K2
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1

NANOG NANOGP8 NANOGP1

3.38e-0455763Arv_SC-HD_1000_K1
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_1000_k-means-cluster#2

NANOG NANOGP8 NANOGP1

4.49e-0461363ratio_SC_vs_EB_1000_K2
CoexpressionAtlasJC_iEC_top-relative-expression-ranked_1000_k-means-cluster#4

NANOG NANOGP8

6.82e-0414562JC_iEC_1000_K4
CoexpressionAtlasratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#2

NANOG NANOGP8 NANOGP1

1.21e-0386063ratio_SC_vs_ECTO_2500_K2
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000

ADGRB3 SEMA5A

1.25e-0319762gudmap_developingGonad_e16.5_epididymis_1000_k5
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_2500_k-means-cluster#2

NANOG NANOGP8 NANOGP1

1.59e-0394563Arv_SC-hpx_blastocyst_2500_K2
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_1000

NANOG SEMA5A NANOGP1

1.75e-0397763PCBC_DE_fibroblast_1000
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_2500_k-means-cluster#5

NANOG NANOGP8 NANOGP1

1.75e-0397863ratio_SC_vs_EB_2500_K5
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000

ADGRB3 SEMA5A

1.76e-0323462gudmap_developingGonad_e18.5_epididymis_1000_k5
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_2500_k-means-cluster#5

NANOG NANOGP8 NANOGP1

1.77e-0398163Arv_SC-H9hpx_2500_K5
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.77e-0398163PCBC_DE_blastocyst_1000
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.79e-0398463PCBC_ratio_SC_vs_EB_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.79e-0398463PCBC_SC_CD34+_1000
CoexpressionAtlasratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.79e-0398463PCBC_ratio_SC_vs_ECTO_1000
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.80e-0398663Arv_SC_fibroblast_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.80e-0398663PCBC_SC_fibroblast_1000
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.80e-0398663Arv_SC-HD_1000
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.80e-0398763Arv_SC-H9hpx_1000
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.80e-0398763Arv_SC-hpx_blastocyst_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.81e-0398963PCBC_SC_1000
CoexpressionAtlasratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.83e-0399363PCBC_ratio_SC_vs_MESO-5_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

NANOG NANOGP8 NANOGP1

1.83e-0399363PCBC_SC_blastocyst_1000
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_2500_k-means-cluster#2

NANOG NANOGP8 NANOGP1

2.52e-03110863Arv_SC_fibroblast_2500_K2
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_2500_k-means-cluster#2

NANOG NANOGP8 NANOGP1

2.55e-03111363Arv_SC-HD_2500_K2
CoexpressionAtlasratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#5

NANOG NANOGP1

2.78e-0329562ratio_SC_vs_MESO_500_K5
CoexpressionAtlasAravindRamakr_StemCell-LF_top-relative-expression-ranked_2500_k-means-cluster#5

NANOG NANOGP8 NANOGP1

2.81e-03115263Arv_SC-LF_2500_K5
CoexpressionAtlasJC_iEC_top-relative-expression-ranked_2500_k-means-cluster#2

NANOG NANOGP8

3.18e-0331662JC_iEC_2500_K2
CoexpressionAtlasAravindRamakr_StemCell-LF_top-relative-expression-ranked_500_k-means-cluster#3

NANOG NANOGP1

3.72e-0334262Arv_SC-LF_500_K3
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500

ADGRB3 SEMA5A

4.36e-0337162gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

ADGRB3 SEMA5A

5.74e-0342762DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
ToppCellTCGA-Testes|World / Sample_Type by Project: Shred V9

NANOG NANOGP8

1.20e-0412862a09b0e221b8749510002304e4d34d6a2eb8867e9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

1.99e-0416562cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

1.99e-04165624f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRB3 SEMA5A

2.21e-0417462015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.28e-04177624943d040eee0f9dceaddc7498171281d170e271f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NANOG SEMA5A

2.28e-0417762a235ff4f37a7622216526191efc4832fb8ed6957
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.28e-04177623645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.28e-0417762a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.28e-04177623f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

ADGRB3 SEMA5A

2.39e-04181628dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRB3 SEMA5A

2.39e-041816233cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

ADGRB3 SEMA5A

2.42e-04182622075efeae633550fb2eb026d0dfd741c8252482e
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRB3 SEMA5A

2.42e-0418262e67f3234165199085c793915ebb1f9bbd845e933
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

ADGRB3 SEMA5A

2.44e-0418362273db6a3b00a93ca852498471187b642b5368185
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

ADGRB3 SEMA5A

2.44e-0418362e3835db4795362b0442d5893baf2a78efcc20428
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.44e-0418362667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ADGRB3 SEMA5A

2.47e-041846221790cdfa3b4036ad413fd44b94e31563116f25f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.50e-0418562a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.50e-04185627092436b4db90289516ed130ade596e3021cffaf
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

ADGRB3 SEMA5A

2.50e-0418562ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 SEMA5A

2.52e-0418662cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellnormal_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

NANOG SEMA5A

2.55e-0418762a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.55e-0418762ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

NANOG SEMA5A

2.55e-0418762d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.55e-0418762530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.55e-0418762958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.55e-041876248bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

ADGRB3 SEMA5A

2.58e-0418862a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.60e-04189622a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.60e-0418962fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.63e-04190625681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 SEMA5A

2.66e-041916278c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.66e-0419162b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.69e-04192624c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.69e-04192626f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A

2.69e-041926224e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.72e-0419362e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.72e-0419362fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.74e-0419462fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.74e-041946260622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRB3 SEMA5A

2.74e-0419462e93de9428c986b8943fc169258847c650cfab0e5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.74e-04194625f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A

2.74e-041946289b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.80e-04196628e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA5A

2.80e-0419662dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

ADGRB3 SEMA5A

2.83e-04197620a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ADGRB3 NANOG

2.86e-04198620c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellbackground-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 SEMA5A

2.86e-041986279f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADGRB3 SEMA5A

2.86e-04198626a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 SEMA5A

2.86e-0419862bd11b0e9e80449aab979a02c1023e0638c431c7c
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A

ADGRB3 SEMA5A

4.51e-04199424159_UP
DrugO,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate

NANOG SEMA5A

5.07e-0421142ctd:C009618
DrugLithium Chloride

ADGRB3 NANOG

1.22e-0332842ctd:D018021
DrugGrape Seed Proanthocyanidins

CLUHP3 NANOG

7.98e-0385242ctd:C511402
DrugCatechin

CLUHP3 NANOG

9.43e-0392842ctd:D002392
Drugpanobinostat

NANOG SEMA5A

1.90e-02133342ctd:C496932
Diseasecolon cancer (implicated_via_orthology)

NANOG NANOGP8 NANOGP1

3.85e-101153DOID:219 (implicated_via_orthology)
Diseaseprecuneus cortex volume measurement

NANOGP8 NANOGP1

2.09e-061452EFO_0010326
Diseasecleft lip

ADGRB3 SEMA5A

9.06e-0428452EFO_0003959
Diseasediet measurement

ADGRB3 NANOGP8

1.18e-02104952EFO_0008111

Protein segments in the cluster

PeptideGeneStartEntry
GQWQEWSSWSQCSVT

ADGRB3

401

O60242
WSNHSWNTQTWCTQS

NANOG

216

Q9H9S0
WSNHSWNTQTWCTQS

NANOGP8

216

Q6NSW7
HTVNGAWSAWTSWSQ

SEMA5A

781

Q13591
WVAAHWTTSQSCAAW

CLUHP3

96

Q96NS8
QSWSNHSWNTQTWCT

NANOGP1

141

Q8N7R0
HSWNTQTWCTQSWNN

NANOGP1

146

Q8N7R0