Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone deacetylase activity

HDAC9 HDAC5 HDAC10

2.64e-04241053GO:0004407
GeneOntologyMolecularFunctionHLA-A specific inhibitory MHC class I receptor activity

LILRA2 LILRB1

2.71e-0451052GO:0030107
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

HDAC9 HDAC5 HDAC10

2.99e-04251053GO:0033558
GeneOntologyMolecularFunctionHLA-B specific inhibitory MHC class I receptor activity

LILRA2 LILRB1

4.05e-0461052GO:0030109
GeneOntologyMolecularFunctionMHC class Ib protein complex binding

LILRA2 LILRB1

5.65e-0471052GO:0023025
GeneOntologyMolecularFunctionprotein phosphatase 1 binding

LILRA2 LILRB1 STAU1

8.18e-04351053GO:0008157
GeneOntologyBiologicalProcessfloor plate development

STIL GLI2 COBL

2.05e-05111053GO:0033504
GeneOntologyBiologicalProcessregulation of dendritic cell apoptotic process

AXL LILRB1 RAPGEF2

4.48e-05141053GO:2000668
GeneOntologyBiologicalProcessdendritic cell apoptotic process

AXL LILRB1 RAPGEF2

4.48e-05141053GO:0097048
GeneOntologyBiologicalProcesspattern specification process

SHROOM3 UNCX STIL MDFI AXIN1 HOXA3 HOXA4 GLI2 DLL3 COBL INVS

7.67e-0552610511GO:0007389
GeneOntologyCellularComponenthistone deacetylase complex

HDAC9 HDAC5 EP400 KMT2E HDAC10

7.25e-05851065GO:0000118
MousePhenodecreased length of allograft survival

LILRA2 MAP7 LILRB1

1.37e-059783MP:0004752
MousePhenowavy neural tube

SHROOM3 EP400 MDFI RAPGEF2

5.15e-0537784MP:0000930
MousePhenoabnormal joint morphology

UNCX MDFI PTH1R AXIN1 PHC2 HOXA3 HOXA4 GLI2 DLL3 HYDIN

6.85e-053977810MP:0002932
MousePhenorib fusion

UNCX MDFI AXIN1 PHC2 DLL3

7.30e-0578785MP:0000154
MousePhenoabnormal visual cortex morphology

LILRA2 HIVEP2 LILRB1

8.88e-0516783MP:0000805
MousePhenoabnormal sclerotome morphology

UNCX MDFI DLL3

1.28e-0418783MP:0006029
MousePhenoabnormal occipital lobe morphology

LILRA2 HIVEP2 LILRB1

1.28e-0418783MP:0000804
DomainHist_deacetyl

HDAC9 HDAC5 HDAC10

2.38e-05111003PF00850
DomainHis_deacetylse_dom

HDAC9 HDAC5 HDAC10

2.38e-05111003IPR023801
Domain-

HDAC9 HDAC5 HDAC10

2.38e-051110033.40.800.20
DomainHis_deacetylse

HDAC9 HDAC5 HDAC10

2.38e-05111003IPR000286
DomainHist_deacetylase_Gln_rich_N

HDAC9 HDAC5

8.48e-0531002IPR024643
DomainHDAC4_Gln

HDAC9 HDAC5

8.48e-0531002PF12203
DomainHistone_deAcase_II_euk

HDAC9 HDAC5

1.69e-0441002IPR017320
DomainZINC_FINGER_C2H2_2

HIVEP2 FOXP2 ZNF184 PEG3 ZNF576 ZNF213 ZNF275 ZNF18 ZNF592 DPF3 GLI2 ZNF516 ZNF324B

2.48e-0477510013PS50157
DomainZINC_FINGER_C2H2_1

HIVEP2 FOXP2 ZNF184 PEG3 ZNF576 ZNF213 ZNF275 ZNF18 ZNF592 DPF3 GLI2 ZNF516 ZNF324B

2.55e-0477710013PS00028
DomainZnf_C2H2

HIVEP2 FOXP2 ZNF184 PEG3 ZNF576 ZNF213 ZNF275 ZNF18 ZNF592 DPF3 GLI2 ZNF516 ZNF324B

3.58e-0480510013IPR007087
DomainZnF_C2H2

HIVEP2 FOXP2 ZNF184 PEG3 ZNF576 ZNF213 ZNF275 ZNF18 ZNF592 DPF3 GLI2 ZNF516 ZNF324B

3.71e-0480810013SM00355
DomainGlyco_hydro_47

USF3 MAN1A2

7.78e-0481002IPR001382
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HDAC9 HDAC5 AXIN1 DLL3 HDAC10

1.26e-0497715MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HDAC9 HDAC5 AXIN1 DLL3 HDAC10

1.53e-04101715M39448
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNC SHROOM3 HIVEP2 TBKBP1 EP400 MDFI ADGRA2 PHC2 FAM83H SUGP2 ZNF592 CDK13 RPTOR ZNF516 COBL ZNF324B GAREM1 BAHCC1 RAB11FIP3

1.86e-0911051101935748872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SHROOM3 HDAC5 SPATA31E1 EP400 BEAN1 KMT2E USF3 AP2B1 GLI2 GAREM1 TECPR1

1.29e-074301101135044719
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SHROOM3 HIVEP2 TBKBP1 TTLL3 IQCN CCDC57 USF3 SUGP2 CDK13 GLI2 RPTOR COBL RIMS1 RAPGEF2 MED27 VPS13B NLK INVS

9.96e-0714891101828611215
Pubmed

Peg3/PW1 Is a Marker of a Subset of Vessel Associated Endothelial Progenitors.

ERG PEG3 CDH5

2.55e-069110328090691
Pubmed

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.

HDAC9 HDAC5 HDAC10

3.63e-0610110328028172
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HDAC9 TTF2 HIVEP2 HDAC5 ERG ZNF184 ZNF275 HOXA3 HOXA4 SUGP2 ZNF592 MYOCD HDAC10

4.26e-068771101320211142
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ERG EP400 IQCN PHC2 SCML2 SUGP2 ZNF592 CDK13 RPTOR ZNF516 RIMS1 PRRC2A

6.51e-067741101215302935
Pubmed

No association of FOXP2 and PTPRZ1 on 7q31 with autism from the Japanese population.

FOXP2 PTPRZ1

9.91e-062110215998549
Pubmed

Retardation of skeletal development and cervical abnormalities in transgenic mice expressing a dominant-negative retinoic acid receptor in chondrogenic cells.

HOXA3 HOXA4

9.91e-06211029636177
Pubmed

A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.

SHROOM3 NLK

9.91e-062110233951476
Pubmed

Histone deacetylases 9 and 10 are required for homologous recombination.

HDAC9 HDAC10

9.91e-062110221247901
Pubmed

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin.

HDAC9 HDAC10

9.91e-062110218926829
Pubmed

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.

ERG CDH5

9.91e-062110218195090
Pubmed

Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.

HDAC9 HDAC5

9.91e-062110217988634
Pubmed

Histone deacetylase expression patterns in developing murine optic nerve.

HDAC9 HDAC5 HDAC10

1.09e-0514110325011550
Pubmed

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin.

HDAC9 HDAC5 MYOCD

1.09e-0514110315601857
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

HDAC9 HDAC5 EP400 PHC2 DPF3 HDAC10

1.12e-05157110630186101
Pubmed

Interaction network of human early embryonic transcription factors.

HIVEP2 TBKBP1 HDAC5 EP400 FOXP2 DPF3 ZNF516 BAHCC1

1.67e-05351110838297188
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SHROOM3 HIVEP2 STIL MAP7 FAM83H MAST4 RPTOR SSX2IP COBL MTCL1 RAPGEF2 FGD6

1.88e-058611101236931259
Pubmed

An inter-species protein-protein interaction network across vast evolutionary distance.

RPGRIP1 CEP170P1 IQCN MDFI CCDC57 PHC2 AP2B1 BEND7 SSX2IP

2.40e-05483110927107014
Pubmed

HDAC family: What are the cancer relevant targets?

HDAC9 HDAC5 HDAC10

2.43e-0518110318824292
Pubmed

Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.

HDAC9 AXIN1 NLK

2.43e-0518110320844743
Pubmed

A human MAP kinase interactome.

HDAC9 FLNC HIVEP2 CCDC88B USF3 AP2B1 COBL RAPGEF2 GAREM1

2.52e-05486110920936779
Pubmed

HDAC5 promotes optic nerve regeneration by activating the mTOR pathway.

HDAC5 RPTOR

2.97e-053110230910408
Pubmed

O-fucosylation of DLL3 is required for its function during somitogenesis.

UNCX DLL3

2.97e-053110225856312
Pubmed

Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.

HDAC9 HDAC5

2.97e-053110223297420
Pubmed

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage.

ERG CDH5

2.97e-053110220030844
Pubmed

Transcriptional regulation of ILT family receptors.

LILRA2 LILRB1

2.97e-053110214662864
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

FOXP2 PTH1R GLI2

3.93e-0521110329659575
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SHROOM3 EP400 FEM1C ADGRA2 MAST4 RBM27 ZNF592 RPTOR ZNF516

4.85e-05529110914621295
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MAP7 AXIN1 MAST4 SSX2IP COBL MTCL1

5.58e-05209110636779422
Pubmed

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

HDAC9 HDAC5

5.92e-054110234119632
Pubmed

De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder.

KMT2E RIMS1

5.92e-054110225284784
Pubmed

Forward spreading in the establishment of a vertebrate Hox expression boundary: the expression domain separates into anterior and posterior zones, and the spread occurs across implanted glass barriers.

HOXA3 HOXA4

5.92e-05411027912569
Pubmed

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation.

HOXA3 HOXA4

5.92e-05411022576400
Pubmed

Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation.

HDAC5 MYOCD

5.92e-054110217940050
Pubmed

Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.

RPTOR FGF21

5.92e-054110226554817
Pubmed

A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus.

HOXA3 HOXA4

5.92e-05411023019676
Pubmed

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.

HDAC9 HDAC5

5.92e-054110210655483
Pubmed

Fetal parathyroids are not required to maintain placental calcium transport.

PTH1R HOXA3

5.92e-054110211306604
Pubmed

Class IIa histone deacetylases: conducting development and differentiation.

HDAC9 HDAC5

5.92e-054110219412888
Pubmed

mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.

HDAC9 HDAC5

5.92e-054110210748098
Pubmed

I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.

MDFI AXIN1

5.92e-054110212192039
Pubmed

Next-generation sequencing to generate interactome datasets.

AAMP EP400 CEP170P1 IQCN MDFI CCDC57 PHC2 HOXA3 ZNF18 BEND7 SSX2IP METTL17 NLK

7.02e-0511471101321516116
Pubmed

Regulation of cytotoxic T lymphocyte triggering by PIR-B on dendritic cells.

LILRA2 LILRB1

9.85e-055110218787130
Pubmed

Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation.

HDAC9 HDAC5

9.85e-055110215546868
Pubmed

Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons.

HOXA3 HOXA4

9.85e-055110219254709
Pubmed

PIR-B Regulates CD4+ IL17a+ T-Cell Survival and Restricts T-Cell-Dependent Intestinal Inflammatory Responses.

LILRA2 LILRB1

9.85e-055110234242819
Pubmed

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.

HDAC9 HDAC5

9.85e-055110215194749
Pubmed

The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.

ERG CDH5

9.85e-055110225584796
Pubmed

Role of PIR-B in autoimmune glomerulonephritis.

LILRA2 LILRB1

9.85e-055110220976309
Pubmed

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

HDAC9 HDAC5

9.85e-055110220188095
Pubmed

Genetic deletion of paired immunoglobulin-like receptor B does not promote axonal plasticity or functional recovery after traumatic brain injury.

LILRA2 LILRB1

9.85e-055110220881122
Pubmed

PirB Overexpression Exacerbates Neuronal Apoptosis by Inhibiting TrkB and mTOR Phosphorylation After Oxygen and Glucose Deprivation Injury.

LILRA2 LILRB1

9.85e-055110227443384
Pubmed

The inhibitory receptor PIR-B negatively regulates neutrophil and macrophage integrin signaling.

LILRA2 LILRB1

9.85e-055110215494528
Pubmed

Ectopically expressed PIR-B on T cells constitutively binds to MHC class I and attenuates T helper type 1 responses.

LILRA2 LILRB1

9.85e-055110219684158
Pubmed

PirB negatively regulates the inflammatory activation of astrocytes in a mouse model of sleep deprivation.

LILRA2 LILRB1

9.85e-055110237146940
Pubmed

PirB functions as an intrinsic suppressor in hippocampal neural stem cells.

LILRA2 LILRB1

9.85e-055110234120891
Pubmed

PirB regulates a structural substrate for cortical plasticity.

LILRA2 LILRB1

9.85e-055110224302763
Pubmed

Spatio-temporal expression of paired immunoglobulin-like receptor-B in the adult mouse brain after focal cerebral ischaemia.

LILRA2 LILRB1

9.85e-055110223927735
Pubmed

Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects.

UNCX DLL3

9.85e-055110217849441
Pubmed

Enhancing motor learning by increasing the stability of newly formed dendritic spines in the motor cortex.

LILRA2 LILRB1

9.85e-055110234437845
Pubmed

Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus.

LILRA2 LILRB1

9.85e-055110237147336
Pubmed

Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity.

LILRA2 LILRB1

9.85e-055110233653799
Pubmed

Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury.

LILRA2 LILRB1

9.85e-055110221087927
Pubmed

Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis.

LILRA2 LILRB1

9.85e-055110220398663
Pubmed

Structure and flexibility of the extracellular region of the PirB receptor.

LILRA2 LILRB1

9.85e-055110230674550
Pubmed

Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence.

LILRA2 LILRB1

9.85e-055110223152562
Pubmed

Regulation of plasmacytoid dendritic cell responses by PIR-B.

LILRA2 LILRB1

9.85e-055110222948046
Pubmed

Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors.

LILRA2 LILRB1

9.85e-05511029054430
Pubmed

Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.

HDAC9 HDAC5

9.85e-055110219893013
Pubmed

Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.

RAPGEF2 CDH5

9.85e-055110219635461
Pubmed

Paternal monoallelic expression of the paired immunoglobulin-like receptors PIR-A and PIR-B.

LILRA2 LILRB1

9.85e-055110210359805
Pubmed

Paired Ig-like Receptor B Inhibits IL-13-Driven Eosinophil Accumulation and Activation in the Esophagus.

LILRA2 LILRB1

9.85e-055110227324131
Pubmed

Characterization of paired Ig-like receptors in rats.

LILRA2 LILRB1

9.85e-055110210586026
Pubmed

Paired immunoglobulin-like receptor B regulates platelet activation.

LILRA2 LILRB1

9.85e-055110225075127
Pubmed

Genomic structure of PIR-B, the inhibitory member of the paired immunoglobulin-like receptor genes in mice.

LILRA2 LILRB1

9.85e-05511029550322
Pubmed

Expression of PirB protein in intact and injured optic nerve and retina of mice.

LILRA2 LILRB1

9.85e-055110222102155
Pubmed

Paired immunoglobulin-like receptors and their MHC class I recognition.

LILRA2 LILRB1

9.85e-055110216011512
Pubmed

Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages.

LILRA2 LILRB1

9.85e-055110223258232
Pubmed

Mast cell regulation via paired immunoglobulin-like receptor PIR-B.

LILRA2 LILRB1

9.85e-055110212403357
Pubmed

Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.

HDAC9 HDAC5

9.85e-055110218332106
Pubmed

Epigenetic silencing of CD8 genes by ThPOK-mediated deacetylation during CD4 T cell differentiation.

HDAC5 HDAC10

9.85e-055110222730529
Pubmed

Functional proteomics mapping of a human signaling pathway.

TTF2 FLNC THSD7A STAU1 MAN1A2 MAST4 ZNF592 CDK13 INVS

1.13e-04591110915231748
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

SHROOM3 UNCX MYOCD

1.17e-0430110329555813
Pubmed

HDAC5-mTORC1 Interaction in Differential Regulation of Ghrelin and Nucleobindin 2 (NUCB2)/Nesfatin-1.

HDAC5 RPTOR

1.47e-046110226357899
Pubmed

Autoimmune arthritis induces paired immunoglobulin-like receptor B expression on CD4+ T cells from SKG mice.

LILRA2 LILRB1

1.47e-046110228664612
Pubmed

HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor.

LILRA2 LILRB1

1.47e-046110212207326
Pubmed

Cell-Autonomous Regulation of Dendritic Spine Density by PirB.

LILRA2 LILRB1

1.47e-046110227752542
Pubmed

The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate.

LILRA2 LILRB1

1.47e-04611029824165
Pubmed

CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression.

LILRA2 LILRB1

1.47e-046110238383888
Pubmed

Inhibition of ANGPTL8 protects against diabetes-associated cognitive dysfunction by reducing synaptic loss via the PirB signaling pathway.

LILRA2 LILRB1

1.47e-046110239095838
Pubmed

PirB is a functional receptor for myelin inhibitors of axonal regeneration.

LILRA2 LILRB1

1.47e-046110218988857
Pubmed

Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.

HDAC9 HDAC5

1.47e-046110216356933
Pubmed

Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.

LILRA2 LILRB1

1.47e-046110227402837
Pubmed

PirB regulates asymmetries in hippocampal circuitry.

LILRA2 LILRB1

1.47e-046110228594961
Pubmed

The p75 receptor mediates axon growth inhibition through an association with PIR-B.

LILRA2 LILRB1

1.47e-046110221881600
Pubmed

Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.

HOXA3 HOXA4

1.47e-04611022891503
Pubmed

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.

HDAC9 HDAC5

1.47e-046110219351956
Pubmed

Impaired dendritic cell maturation and increased T(H)2 responses in PIR-B(-/-) mice.

LILRA2 LILRB1

1.47e-046110212021780
InteractionTOP3B interactions

FLNC SHROOM3 HIVEP2 TBKBP1 EP400 MDFI ADGRA2 PHC2 FAM83H STAU1 SUGP2 ZNF592 CDK13 RPTOR ZNF516 SSX2IP COBL ZNF324B PRRC2A GAREM1 BAHCC1 RAB11FIP3

5.66e-06147010522int:TOP3B
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

HIVEP2 ZNF184 PEG3 ZNF576 ZNF213 ZNF275 ZNF18 ZNF592 GLI2 ZNF516 ZNF324B

4.54e-05718651128
GeneFamilyHistone deacetylases, class IIA

HDAC9 HDAC5

7.60e-054652992
GeneFamilyTubulin tyrosine ligase family

TTLL3 TTLL13

1.13e-0314652779
GeneFamilyPDZ domain containing

SHROOM3 MAST4 RIMS1 RAPGEF2

2.18e-031526541220
GeneFamilyAtaxins|Trinucleotide repeat containing

EP400 FOXP2

3.62e-0325652775
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERG STIL TMTC1 MYOCD RIMS1 MTCL1 CDC6 PARPBP

2.30e-081901098e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 THSD7A MAP7 PTH1R MAST4 COBL GAREM1 RAB11FIP3

2.60e-0819310983866667dd221612589ae50f5c52f73a183a49ce6
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

THSD7A ERG PTH1R TMTC1 RIMS1 RAPGEF2 CDH5

4.44e-071901097a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HDAC9 PRMT8 THSD7A ANK1 PTH1R MAST4 PTPRZ1

4.77e-07192109725460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MAP7 PTH1R MAST4 COBL GAREM1 RAB11FIP3

4.94e-07193109782e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERG TMTC1 MYOCD RIMS1 MTCL1 CDC6 PARPBP

4.94e-071931097516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MAP7 PTH1R MAST4 COBL GAREM1 RAB11FIP3

5.11e-0719410977002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MAP7 PTH1R MAST4 COBL GAREM1 RAB11FIP3

5.11e-0719410975eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPIPB15 CCDC57 ZNF592 HDAC10 RAPGEF2 RAB11FIP3

1.07e-061361096edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPIPB15 CCDC57 ZNF592 HDAC10 RAPGEF2 RAB11FIP3

1.07e-06136109603e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

THSD7A FOXP2 RPTOR COBL MYOCD MTCL1

3.29e-061651096531804467601e1ee1f771cffa21501f6d464ae10
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAP7 MAST4 FGD6 GAREM1

3.91e-061701096269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTF2 SHROOM3 STIL PTH1R HOXA3 RPTOR

3.91e-061701096b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AXL PEG3 MDFI GLI2 MYOCD RIMS1

5.26e-06179109602c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A ERG TMTC1 MAST4 RAPGEF2 CDH5

5.26e-0617910962a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

THSD7A ERG TMTC1 MAST4 RAPGEF2 CDH5

6.75e-06187109640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

FLNC ERG ADGRA2 TMTC1 CARD6 CDH5

6.96e-061881096c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

SHROOM3 FOXP2 MAP7 MAST4 COBL GAREM1

6.96e-061881096707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

SHROOM3 FOXP2 MAP7 PTPRZ1 RIMS1 GAREM1

7.18e-06189109684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellCOPD-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

DIP2C-AS1 ERG MAST4 COBL MTCL1 RAPGEF2

7.40e-061901096379dbac19110b76079a7a53209569e060a852acb
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

ERG MDFI PTH1R RPTOR MYOCD MTCL1

7.62e-06191109686ce98d2c90c196474b06869de888cf5d1eed196
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ERG AXL ADGRA2 TMTC1 GLI2 MYOCD

7.62e-061911096fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 FOXP2 MAP7 MAST4 COBL GAREM1

7.62e-061911096e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SHROOM3 FOXP2 MAP7 MAST4 COBL GAREM1

7.85e-061921096499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

SHROOM3 FOXP2 MAP7 MAST4 COBL HYDIN

7.85e-0619210960644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERG AXL ADGRA2 TMTC1 GLI2 MYOCD

7.85e-061921096bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERG AXL ADGRA2 TMTC1 GLI2 MYOCD

7.85e-061921096b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SHROOM3 FOXP2 MAP7 MAST4 COBL GAREM1

7.85e-061921096efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 PTH1R MAST4 RAPGEF2 VPS13B RAB11FIP3

7.85e-061921096e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAP7 MAST4 RIMS1 GAREM1

8.09e-0619310962bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MAP7 APCDD1L COBL NLK GAREM1

8.33e-06194109646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 MAP7 APCDD1L COBL NLK GAREM1

8.33e-061941096abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 FOXP2 MAP7 COBL HYDIN GAREM1

8.33e-06194109693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 FOXP2 MAP7 MAST4 COBL GAREM1

8.58e-0619510966477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERG AXL ADGRA2 TMTC1 GLI2 MYOCD

8.83e-061961096b8759e6231e0254797d6c30930407b79440c57bb
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ERG TMTC1 MAST4 APCDD1L CDH5

9.36e-06198109658508a8df2714d769f137794c29441a7bd38b350
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

THSD7A ERG ANK1 TMTC1 CDC6 CDH5

9.63e-061991096bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC THSD7A ERG ANK1 MAST4 CDH5

9.63e-0619910966a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CIART APCDD1L MTCL1 NLK GAREM1

3.63e-051521095eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAP7 MAST4 RIMS1

4.91e-0516210955c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

ERG HOXA3 HOXA4 MALRD1 BAHCC1

5.36e-0516510957b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 STIL MDFI BEND7 CDC6

5.52e-0516610958d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 STIL MDFI BEND7 CDC6

5.52e-051661095f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 STIL MDFI BEND7 CDC6

5.52e-051661095a5074c96c6561273029aceb93402a7e038140f50
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPIPB15 TBKBP1 ANK1 DPF3 GLI2

5.84e-0516810958f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

THSD7A ERG HOXA3 TMTC1 CDH5

5.84e-0516810958c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC PEG3 PTPRZ1 GLI2 HYDIN

6.89e-051741095f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXP2 NPIPB9 GLI2 CARD6 RIMS1

6.89e-0517410953f0a5ce074675d57d479fa069385a1b3071e884e
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

HDAC9 ADGRA2 PTH1R HOXA3 TMTC1

6.89e-0517410958393f0b43c767839c1630bcb952d62b42efc788d
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC FOXP2 ADGRA2 MYOCD MED27

7.28e-051761095a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

DIP2C-AS1 ERG MAST4 COBL MTCL1

7.28e-0517610950c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AXL ADGRA2 TMTC1 GLI2 MYOCD

7.47e-0517710954943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AXL ADGRA2 TMTC1 GLI2 MYOCD

7.47e-0517710953f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ERG ZNF184 HOXA3 CDH5 TECPR1

7.47e-0517710956da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PEG3 IQCN BCLAF3 TMTC1 PTPRZ1

7.68e-051781095a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC THSD7A ERG SCML2 CDH5

7.68e-051781095ad3de3e03a401dac64431a541899445262246347
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 FOXP2 PTH1R COBL MTCL1

7.88e-05179109504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAST4 RIMS1 GAREM1

8.09e-051801095b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRMT8 ERG FOXP2 PTH1R PTPRZ1

8.09e-051801095a407376209d80177bf7fc4200219030c83cb5f14
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTF2 ADAP1 AXL CCDC57 PARPBP

8.52e-05182109521dcab170ffeef89faa9fee5008568cb6e15c694
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBKBP1 ERG BEAN1 ADGRA2 CDH5

8.52e-0518210953b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBKBP1 ERG BEAN1 ADGRA2 CDH5

8.52e-051821095ab5761bf9af439231cd0f487b6467e372672a517
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CIART TMTC1 COBL MYOCD MTCL1

8.75e-051831095a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PEG3 MDFI GLI2 MYOCD RIMS1

8.75e-0518310957eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERG TMTC1 MYOCD RIMS1 MTCL1

8.75e-051831095e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 USF3 MAST4 CDK13 PRRC2A

8.97e-051841095e6bf826be31e1723e24c366fc5a1cee9b15589bc
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ERG TMTC1 CARD6 CDH5

8.97e-051841095842473fa415575441b595073a994b6d621169776
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD7A ERG TMTC1 MAST4 CDH5

8.97e-0518410950f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXP2 PEG3 GLI2 MYOCD RIMS1

9.20e-0518510956712512100ccef456d2e2bd201d0987986c92ac9
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

SHROOM3 PRMT8 MAP7 MAST4 RIMS1

9.20e-051851095cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A TMTC1 MAST4 APCDD1L CDH5

9.20e-051851095fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC AXL GLI2 MYOCD MTCL1

9.20e-051851095e58a009aaf342be019a909747b1895d5987d4daf
ToppCellControl-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

ERG AXL MDFI TMTC1 PTPRZ1

9.20e-051851095d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

ERG MAST4 COBL MTCL1 RAPGEF2

9.44e-051861095def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 FOXP2 MAP7 COBL MTCL1

9.44e-0518610954e94158db52df41d71e67b02b9895a358eebee0f
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

ERG SCML2 CARD6 CDH5 TECPR1

9.44e-0518610952e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

ERG SCML2 CARD6 CDH5 TECPR1

9.44e-051861095c3449e54454009973818fc1101933c6f0168258c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 FOXP2 MAST4 MTCL1 HYDIN

9.44e-051861095b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 FOXP2 MAP7 MAST4 MTCL1

9.44e-051861095e83718fabb057100835d3357df407f283d23fe16
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAST4 RIMS1 GAREM1

9.68e-051871095ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC FOXP2 MYOCD RIMS1 MTCL1

9.68e-0518710953912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AXL ADGRA2 TMTC1 GLI2 MYOCD

9.93e-051881095b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHROOM3 FOXP2 MAP7 MAST4 COBL

9.93e-051881095c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 FOXP2 MAP7 MAST4 GAREM1

9.93e-0518810954bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC AXL GLI2 MYOCD MTCL1

9.93e-0518810954d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 AXL BEND7 COBL MTCL1

9.93e-05188109543a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERG TMTC1 MYOCD RIMS1 MTCL1

9.93e-0518810953004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 ERG ADGRA2 TMTC1 MYOCD

1.02e-0418910957fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ERG MDFI PTH1R GLI2 MYOCD

1.02e-04189109544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERG TMTC1 MYOCD RIMS1 MTCL1

1.02e-041891095b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 ERG ADGRA2 TMTC1 MYOCD

1.02e-04189109506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

THSD7A ERG MAP7 HOXA3 MALRD1

1.02e-041891095555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

THSD7A ERG ADGRA2 TMTC1 CDH5

1.02e-04189109504b565855f58ca0f343904d04be657b66e109076
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 PTH1R COBL HYDIN GAREM1

1.02e-041891095aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERG TMTC1 MYOCD RIMS1 MTCL1

1.02e-041891095f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 PTH1R COBL HYDIN GAREM1

1.02e-0418910958977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FLNC MAST4 DPF3 MYOCD GAREM1

1.02e-0418910950a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

SHROOM3 PRMT8 MAST4 RIMS1 GAREM1

1.04e-041901095756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FLNC MAST4 DPF3 MYOCD GAREM1

1.04e-04190109593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

HDAC9 FLNC TMTC1 DPF3 MYOCD

1.04e-041901095918ad5037881212008f9f69d5df5da91fd01422c
Drug6-mercaptopurine monohydrate; Down 200; 10uM; PC3; HG-U133A

EP400 MAP7 AXIN1 MAST4 SUGP2 ZNF592 SSX2IP RAPGEF2 RAB11FIP3

3.31e-071951069667_DN
Drug2,4,4'-trichlorobiphenyl

RPGRIP1 TTF2 PRMT8 ANK1 EP400 FOXP2 ZNF184 STIL MAP7 SCML2 GLI2 FGF21 BEND7 RIMS1 CDC6 PARPBP GMPPA CDH5 TTLL13 S100PBP

7.06e-06141110620ctd:C081766
Drug2,4,5,2',5'-pentachlorobiphenyl

RPGRIP1 TTF2 PRMT8 ANK1 EP400 FOXP2 ZNF184 STIL MAP7 SCML2 GLI2 FGF21 BEND7 RIMS1 CDC6 PARPBP GMPPA CDH5 TTLL13 S100PBP

9.63e-06144110620ctd:C009828
DiseaseManic Disorder

HDAC5 THSD7A ZNF592 RIMS1

1.22e-04711054C0024713
DiseaseManic

HDAC5 THSD7A ZNF592 RIMS1

1.76e-04781054C0338831
DiseaseDepression, Bipolar

HDAC5 THSD7A ZNF592 RIMS1

1.85e-04791054C0005587
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

HDAC9 HDAC5 AP2B1 PTPRZ1

3.47e-04931054DOID:3525 (biomarker_via_orthology)
Diseaseurinary albumin to creatinine ratio

SHROOM3 FOXP2 PHC2 SSX2IP BAHCC1

4.60e-041791055EFO_0007778
Diseaseurea measurement

SHROOM3 UNCX

5.54e-04101052EFO_0011005
Diseasefibroblast growth factor 21 measurement

PHC2 FGF21

6.76e-04111052EFO_0010783
Diseasecigarettes per day measurement

TTF2 THSD7A CIART PHC2 MAN1A2 RBM27 MED27

9.88e-044381057EFO_0006525
Diseasecoronary artery disease

HDAC9 SHROOM3 HIVEP2 THSD7A ERG TENT4A CIART MALRD1 MAST4 RPTOR RAPGEF2 FGD6

1.11e-03119410512EFO_0001645
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 1 measurement

LILRA2 LILRB1

1.28e-03151052EFO_0008208
Diseaseamenorrhea, response to antineoplastic agent

TMTC1 RIMS1

1.28e-03151052EFO_0010269, GO_0097327
Diseasealcohol consumption measurement

THSD7A UNCX NPIPB9 PHC2 MAST4 RBM27 RPTOR FGF21 ZNF516 COBL MYO15A BAHCC1

1.55e-03124210512EFO_0007878
Diseaseforced expiratory volume

HDAC9 THSD7A ANK1 ZNF184 STIL HOXA3 MTCL1 FGD6 GAREM1

2.04e-037891059EFO_0004314
DiseaseDyschondroplasias

PTH1R DLL3

2.06e-03191052C0013366
Diseaserenal system measurement

SHROOM3 UNCX

2.29e-03201052EFO_0004742
Diseaseleprosy, Crohn's disease

ADAP1 CCDC88B

2.29e-03201052EFO_0000384, EFO_0001054
Diseasemajor depressive disorder

HIVEP2 THSD7A FOXP2 ZNF184

2.32e-031551054MONDO_0002009
DiseaseCraniofacial Abnormalities

FOXP2 FAM83H HOXA3 DLL3

2.38e-031561054C0376634
Diseasebone density

TTF2 HDAC5 AXIN1 COBL MTCL1 MYO15A

2.68e-033881056EFO_0003923

Protein segments in the cluster

PeptideGeneStartEntry
LQLTPKPQHHVGSPG

C2orf16

376

Q68DN1
RRPSQPHTQSGGTIH

EP400

221

Q96L91
AKVSGATRHPQPKGH

BAHCC1

1616

Q9P281
ATRHPQPKGHGSRET

BAHCC1

1621

Q9P281
HKNSQRQGPFSHGAP

CCDC187

21

A0A096LP49
KPPNAFVEGSHGIHR

AP2B1

576

P63010
QRHPGPLGAPVSHSK

CCDC88B

1421

A6NC98
QGSPIHVLKGTEGHQ

AAMP

246

Q13685
PAGTRGNLAHRHPNN

ADGRA2

1161

Q96PE1
HSRQPQKKPHSVSNG

SSX2IP

511

Q9Y2D8
HPNAAGKNGLTPLHV

ANK1

561

P16157
TGHGHPTPQSKAAQP

ERG

261

P11308
PQHRPSLQKHPSTGG

APCDD1L

466

Q8NCL9
NATFQPAKIGHPHGL

ADAP1

181

O75689
VHHVSTQPSCPGRGK

PRMT8

46

Q9NR22
NIPKNSGHLPIHVAA

ASB14

276

A6NK59
LFPPLHTGRAGQRQH

DLL3

591

Q9NYJ7
AQVQKPPRHAPGAHG

CDH5

686

P33151
VAPVKTGPGQHLNHS

CDK13

1076

Q14004
VPVKHRLGHAGGNQS

RBM27

746

Q9P2N5
GRPHPHGQSVITVIG

RAB11FIP3

371

O75154
DRQTQPQPHGHVPGK

IQCN

801

Q9H0B3
GAPDAKLQPPGQHHR

MTCL1

11

Q9Y4B5
ISPARPKSHAINHGT

PARPBP

331

Q9NWS1
GPRTHVQAGHLPKPT

LILRA2

16

Q8N149
HPRGKNNFSPLHLAV

FEM1C

476

Q96JP0
NGKPVGSPHVVTSHQ

MAP7

651

Q14244
GHHPSQGRIQEAPKL

HOXA3

426

O43365
GRHHEPGPGQLTKSA

MYO15A

991

Q9UKN7
HRNENHRPQKGPDGT

DPF3

241

Q92784
NTTSPNGKHRVTHLP

CSNKA2IP

346

A0A1B0GTH6
QSEAHGLPLHLPGNK

FGF21

136

Q9NSA1
SPKKGRCSGHNHVPN

GAREM1

356

Q9H706
KASPPITHHSIVNGQ

FOXP2

306

O15409
GGHPVPKFPTRVHVQ

FLNC

1231

Q14315
SHSNHIPQLQAKGPV

KMT2E

1301

Q8IZD2
KPGHLGHPQQTEVAP

GLI2

1276

P10070
VRDHPGQHGKTPSPQ

NPIPB7

41

O75200
LVGKPSENHPLHNSG

MED27

76

Q6P2C8
GAKAHILRGPHKQPS

NLK

371

Q9UBE8
ANLEINQAHPPKGRH

PTPRZ1

1296

P23471
VRDHPGQHGKTPSPQ

NPIPB15

41

A6NHN6
QHSPLGAVKSPQHIS

MYOCD

636

Q8IZQ8
HSLVASKPPRSHNGN

PEG3

836

Q9GZU2
GSPSQHQFHPGRRKR

TENT4A

156

Q5XG87
AKQLTNHSPPAPRHG

RIMS1

441

Q86UR5
SHQSLRPPKDHTLGN

MALRD1

1546

Q5VYJ5
PSGTGAHGHKQVPRS

FAM189B

601

P81408
QDTHPERLAKHTPGG

GMPPA

266

Q96IJ6
AVQNGLALVRPPGHH

HDAC10

121

Q969S8
RVKKGHAHVQPQPSG

HYDIN

961

Q4G0P3
PQKVQGGHSPDDHRV

BCLAF3

131

A2AJT9
IRTSHIGKPHPQSFQ

CARD6

886

Q9BX69
HGSSGTRKPQPHENS

AXIN1

651

O15169
TYQGHHTPPVQKGLR

MT-CO3

66

P00414
PKPISPQQKSAHHEG

COBL

811

O75128
PQQKSAHHEGRNPLG

COBL

816

O75128
PKQKSSPVNNHHSPG

CEP170P1

226

Q96L14
APSRHLGKHQPRSAQ

CCDC57

756

Q2TAC2
KENGPPHSHTLKGRR

CDC6

81

Q99741
LGGPKAHRKLQTHPS

MDFI

121

Q99750
ASPHQPIVIHSSGKN

MAST4

1136

O15021
GHNELRPIARKGHSP

MAN1A2

201

O60476
TLHHQRGIRNFPTPG

BEND7

491

Q8N7W2
KEPTPGGLNHSLPQH

HDAC5

196

Q9UQL6
PTNGKNHSVSRHPKL

HDAC9

161

Q9UKV0
QISAHGQKHRAVPAP

FAM83H

1046

Q6ZRV2
SGHSPGRHQQEQRTP

BEAN1

186

Q3B7T3
TSSGHGPAHTKPLNR

S100PBP

121

Q96BU1
AGPPGKAQTQSPHLH

HOXA4

291

Q00056
SGFLQKRPHRQHPGI

METTL17

41

Q9H7H0
VRDHPGQHGKTPSPQ

NPIPB9

56

F8W1W9
AKLNTGQSPGHSPGH

PRM3

6

Q9NNZ6
HGLQPEPRTGHIQDK

PCARE

1261

A6NGG8
AGQNPPHHRTPRNKV

INVS

821

Q9Y283
GQPATHGQTKTHRRP

MRPL3

226

P09001
QDPLGKHQTRVAPAH

PUSL1

261

Q8N0Z8
GHRQLHTAGAPVPEK

RPGRIP1

146

Q96KN7
GSGLQHRTRHVVAPP

THSD7A

211

Q9UPZ6
GPRTHVQAGHLPKPT

LILRB1

16

Q8NHL6
RQGSVTAPGGHPRHK

PRRC2A

1486

P48634
SPEHLTSGPQHRKAA

SHROOM3

126

Q8TF72
ATPKGHHCPVKNRGI

SPATA31E1

1381

Q6ZUB1
KLSPGQLSPHSVNVH

DIP2C-AS1

176

Q8N8Z3
GPGSHEVQQVTVHKP

ODF3L1

236

Q8IXM7
PASPTNKGVHIHQAG

RPTOR

861

Q8N122
SGNQHTPSHPKQRGS

CIART

71

Q8N365
RHLPGQKTPTLAGRH

LINC00615

76

Q96LM1
HIRAHTNLPGPLTKA

ERVK-25

561

P63136
QQPHGHPTSSRPVNK

RAPGEF2

1451

Q9Y4G8
RQTKPCHGQEPHGAA

ZNF516

886

Q92618
PHTRNSIKPSSHNGP

STIL

516

Q15468
TANLHKPGGSQQCHP

PHC2

411

Q8IXK0
QPSSLPGHPHRENGK

TMTC1

261

Q8IUR5
ILKNNISSGHVPHGP

STAU1

471

O95793
ATTNGHPQLPGHAKP

PTH1R

526

Q03431
VNKHGNFGPHLDPKR

SCML2

361

Q9UQR0
TVCHRTGVQPHEPKG

TECPR1

1106

Q7Z6L1
KVKPPGGHSPQVNHL

ZNF592

1081

Q92610
GGHSPQVNHLKRPVS

ZNF592

1086

Q92610
KHHGRQAPGLSQAKP

SUGP2

711

Q8IX01
QKLDHQHSPRIGSPG

FGD6

1281

Q6ZV73
QHSPRIGSPGNHKSP

FGD6

1286

Q6ZV73
HGPQRSLHVPGLNKT

AXL

186

P30530
NVPTPQTFGGKHLVH

USF3

621

Q68DE3
KAQLPSPHVLRHQGQ

TTLL3

576

Q9Y4R7
HGAGLSQLPKQRHQP

VPS13B

3826

Q7Z7G8
HSHSAQPPALLKEGR

ZNF213

171

O14771
SEKQLGQHLPNPHSG

ZNF18

366

P17022
LITHQRSHGPAAKPT

ZNF576

86

Q9H609
HIRAHTNLPGPLTKA

ERVK-19

566

Q9WJR5
AGHSEPGVSQTPRHK

TRBV17

16

A0A087X0K7
GRDHSRDHPGKSQVP

nan

111

Q6ZVU0
QHEKRGPHALQSSGP

HIVEP2

2281

P31629
DGKRGSPQNLPIEHH

ZNF275

86

Q9NSD4
KPPSHHVKAGFQGRR

TBKBP1

446

A7MCY6
PSLTQHQRIHTGEKP

ZNF184

291

Q99676
VHSHNSISKPQKGGP

TTF2

266

Q9UNY4
KSLPQGHFQERPETH

TTF2

306

Q9UNY4
TKKGPGRPAHNSHPT

UNCX

166

A6NJT0
RLQHPGPQGQKKLHE

TTLL13

616

A6NNM8
TPGPGFLQGHHRKVR

ZNF324B

516

Q6AW86