Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycerol kinase activity	GK GK2	9.32e-05	3	112	2	GO:0004370
Domain	Carb_kinase_FGGY_CS	GK GK2	1.05e-04	3	111	2	IPR018483
Domain	AP_complex_bsu_1_2_4	AP2B1 AP4B1	1.05e-04	3	111	2	IPR016342
Domain	B2-adapt-app_C	AP2B1 AP4B1	1.05e-04	3	111	2	PF09066
Domain	B2-adapt-app_C	AP2B1 AP4B1	2.08e-04	4	111	2	SM01020
Domain	B-adaptin_app_sub_C	AP2B1 AP4B1	2.08e-04	4	111	2	IPR015151
Domain	Glycerol_kin	GK GK2	2.08e-04	4	111	2	IPR005999
Domain	AP_beta	AP2B1 AP4B1	3.46e-04	5	111	2	IPR026739
Domain	FGGY_KINASES_1	GK GK2	3.46e-04	5	111	2	PS00933
Domain	Carb_kinase_FGGY_C	GK GK2	3.46e-04	5	111	2	IPR018485
Domain	FGGY_KINASES_2	GK GK2	3.46e-04	5	111	2	PS00445
Domain	Carb_kinase_FGGY_N	GK GK2	5.17e-04	6	111	2	IPR018484
Domain	FGGY_C	GK GK2	5.17e-04	6	111	2	PF02782
Domain	Beta2_adaptin/TBP_C_dom	AP2B1 AP4B1	5.17e-04	6	111	2	IPR012295
Domain	-	AP2B1 AP4B1	5.17e-04	6	111	2	3.30.310.10
Domain	ETS_DOMAIN_1	ETV7 ETV6 ELK4	6.01e-04	28	111	3	PS00345
Domain	ETS_DOMAIN_2	ETV7 ETV6 ELK4	6.01e-04	28	111	3	PS00346
Domain	Ets	ETV7 ETV6 ELK4	6.01e-04	28	111	3	PF00178
Domain	ETS	ETV7 ETV6 ELK4	6.01e-04	28	111	3	SM00413
Domain	Ets_dom	ETV7 ETV6 ELK4	6.01e-04	28	111	3	IPR000418
Domain	ETS_DOMAIN_3	ETV7 ETV6 ELK4	6.01e-04	28	111	3	PS50061
Domain	Carb_kinase_FGGY	GK GK2	7.21e-04	7	111	2	IPR000577
Domain	FGGY_N	GK GK2	7.21e-04	7	111	2	PF00370
Domain	Coatomer/calthrin_app_sub_C	AP2B1 AP4B1	9.57e-04	8	111	2	IPR009028
Domain	Orgcat_transp/SVOP	SLC22A2 SVOP	1.23e-03	9	111	2	IPR004749
Domain	PNT	ETV7 ETV6	1.86e-03	11	111	2	PS51433
Domain	SAM_PNT	ETV7 ETV6	1.86e-03	11	111	2	PF02198
Domain	Pointed_dom	ETV7 ETV6	1.86e-03	11	111	2	IPR003118
Domain	SAM_PNT	ETV7 ETV6	1.86e-03	11	111	2	SM00251
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DYNC1H1	3.04e-03	14	111	2	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DYNC1H1	3.04e-03	14	111	2	IPR024743
Domain	MT	DNAH14 DYNC1H1	3.04e-03	14	111	2	PF12777
Domain	AAA_8	DNAH14 DYNC1H1	3.04e-03	14	111	2	PF12780
Domain	DHC_fam	DNAH14 DYNC1H1	3.49e-03	15	111	2	IPR026983
Domain	Clathrin/coatomer_adapt-like_N	AP2B1 AP4B1	3.49e-03	15	111	2	IPR002553
Domain	Dynein_heavy	DNAH14 DYNC1H1	3.49e-03	15	111	2	PF03028
Domain	Adaptin_N	AP2B1 AP4B1	3.49e-03	15	111	2	PF01602
Domain	Dynein_heavy_dom	DNAH14 DYNC1H1	3.49e-03	15	111	2	IPR004273
Domain	MFS	SLC18B1 SLC22A2 MFSD8 SVOP	3.94e-03	108	111	4	PS50850
Domain	WD40	WSB1 IFT140 RBBP5 LLGL2 WDR35 NSMAF	4.52e-03	259	111	6	PF00400
Domain	WD40	WSB1 IFT140 RBBP5 LLGL2 WDR35 NSMAF	5.33e-03	268	111	6	SM00320
Domain	WD40_repeat	WSB1 IFT140 RBBP5 LLGL2 WDR35 NSMAF	5.72e-03	272	111	6	IPR001680
Pubmed	Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6.	ETV7 ETV6	1.03e-05	2	112	2	11108721
Pubmed	MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression.	MACC1 FASN	1.03e-05	2	112	2	28339092
Pubmed	Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.	GK GK2	1.03e-05	2	112	2	30662012
Pubmed	Lysosomal dysfunction and impaired autophagy in a novel mouse model deficient for the lysosomal membrane protein Cln7.	HEXB MFSD8	3.08e-05	3	112	2	26681805
Pubmed	The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).	ETV7 ETV6	3.08e-05	3	112	2	12588862
Pubmed	Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.	GK GK2	3.08e-05	3	112	2	28852571
Pubmed	PIKfyve-dependent regulation of the Cl- channel ClC-2.	PIKFYVE CLCN2	3.08e-05	3	112	2	19232516
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	DPP6 SPTBN1 LPCAT4 SLC7A8 NAV3 C1QC ATP1A3 SVOP	5.23e-05	405	112	8	38187761
Pubmed	Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.	RAB12 RAB40B DYNC1H1	5.49e-05	23	112	3	20360680
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HEXB FOXRED1 MYCBP2 ADAM9 POLG SPTBN1 XPC RBM22 AP2B1 OTOF NAV3 R3HDM1 DYNC1H1 DNM2	6.77e-05	1285	112	14	35914814
Pubmed	Biosynthesis of triacylglycerols.	FASN GK ACSL5	1.00e-04	28	112	3	8944226
Pubmed	The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.	GK GK2	1.02e-04	5	112	2	7987308
Pubmed	A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland.	ANO1 CLCN2	1.02e-04	5	112	2	25646474
Pubmed	Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease.	AMH IFT140	1.02e-04	5	112	2	23469164
Pubmed	Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells.	AP2B1 OTOF	1.53e-04	6	112	2	23719817
Pubmed	Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.	POLG FASN	1.53e-04	6	112	2	31358769
Pubmed	Molecular and functional characterization of clathrin- and AP-2-binding determinants within a disordered domain of auxilin.	GAK AP2B1	1.53e-04	6	112	2	12732633
Pubmed	The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1.	AP2B1 AP4B1	1.53e-04	6	112	2	12419313
Pubmed	Cranioectodermal Dysplasia	IFT140 WDR35	1.53e-04	6	112	2	24027799
Pubmed	Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis.	IFT140 WDR35	1.53e-04	6	112	2	29220510
Pubmed	Role for the IFT-A Complex in Selective Transport to the Primary Cilium.	IFT140 WDR35	1.53e-04	6	112	2	27806291
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RBBP5 INTS3 NCAPG2 FASN AP2B1 DYNC1H1 DNM2	2.03e-04	370	112	7	22922362
Pubmed	Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.	IFT140 WDR35	2.14e-04	7	112	2	27932497
Pubmed	ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility.	TBC1D15 GK2	2.14e-04	7	112	2	33536340
Pubmed	Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.	GK GK2	2.14e-04	7	112	2	10444329
Pubmed	Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant.	INTU FANCB	2.14e-04	7	112	2	21948523
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MACC1 INTU FOXRED1 SPTBN1 NOL6 LPCAT4 XPC SSRP1 RBM22 FASN AP2B1 DGKK ATP1A3 FBXO15	2.25e-04	1442	112	14	35575683
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCBP2 POLG TMC6 COMTD1 RALGAPA2 PRAG1 PIKFYVE FASN LLGL2 DISP2 SLC52A2 DYNC1H1	2.38e-04	1105	112	12	35748872
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SPTBN1 INTS3 FASN DYNC1H1 ACSL5 DNM2	2.59e-04	272	112	6	31010829
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 SPTBN1 NOL6 DHX8 FASN AP2B1 DYNC1H1 ZMYM3 DNM2	2.71e-04	653	112	9	22586326
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	RBBP5 SPTBN1 XPC SSRP1 AP2B1 ZMYM3 DNM2	2.97e-04	394	112	7	27248496
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	INTU ADAM9 NAV3 DISP2 R3HDM1 DYNC1H1 ZMYM3	3.61e-04	407	112	7	12693553
Pubmed	TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.	IFT140 WDR35	3.65e-04	9	112	2	20889716
Pubmed	Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.	PCSK1 HEXB AP2B1	3.91e-04	44	112	3	27534441
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	MYCBP2 NOL6 AP2B1	3.91e-04	44	112	3	26471122
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	COL15A1 SPTBN1 SLC5A1 FASN GK GK2 FCGBP SLC22A2 CDK5RAP2 DYNC1H1 DNM2	4.49e-04	1016	112	11	19056867
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	HEXB POLG UGT3A1 NEU3 OVGP1 GYS2	5.45e-04	313	112	6	20800603
Pubmed	OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis.	SPTBN1 FASN	5.55e-04	11	112	2	36411454
Pubmed	Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.	AP2B1 ST8SIA2 ATP1A3	6.40e-04	52	112	3	20114047
Pubmed	USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.	MYCBP2 DYNC1H1	6.64e-04	12	112	2	29293652
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	SCO2 NEK10 TMC6 MR1 NRG2 NEU3 TRIP4 OVGP1 DISP2 C4orf33	7.64e-04	915	112	10	32393512
Pubmed	Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.	RAB12 WDR35 DYNC1H1	7.96e-04	56	112	3	27103069
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SCO2 IFT140 INTU LPCAT4 XPC SSRP1 RALGAPA2 TRIP4 PANK4 TARBP2 ZMYM3	9.69e-04	1116	112	11	31753913
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SCO2 TBC1D15 GAK MYCBP2 SPTBN1 SSRP1 PIGU NCAPG2 TRIP4 PANK4 CDK5RAP2 ADI1 TARBP2	1.01e-03	1487	112	13	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DPP6 INTU MYCBP2 POLG TMC6 INTS3 DNAH14 PANK4 ELK4 RAB40B ADI1 ALG12 NSMAF	1.02e-03	1489	112	13	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCO2 TBC1D15 FOXRED1 COL15A1 MYCBP2 POLG SSRP1 PIGU PIKFYVE GK PANK4 CDK5RAP2 R3HDM1	1.07e-03	1496	112	13	32877691
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TCAF2 NOL6 XPC INTS3 PIGU RBM22 CDK5RAP2 DNM2	1.10e-03	638	112	8	31182584
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	IFT140 INTU MYCBP2 SSRP1 PIGU NCAPG2 FANCB AP2B1 WDR35 TARBP2 DYNC1H1 DNM2	1.15e-03	1321	112	12	27173435
Pubmed	The interactome of the prostate-specific protein Anoctamin 7.	XPC FASN AP2B1	1.23e-03	65	112	3	32176628
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RBBP5 ADAM9 NOL6 INTS3 NCAPG2 LLGL2 AP4B1 DNM2	1.24e-03	650	112	8	38777146
Pubmed	Defining the membrane proteome of NK cells.	HEXB GAK MYCBP2 LPCAT4 PIGU NCAPG2 FASN AP2B1 ALG12 DYNC1H1 ACSL5	1.39e-03	1168	112	11	19946888
Pubmed	O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma.	RBM22 FASN AP2B1 DYNC1H1 ACSL5	1.42e-03	254	112	5	36604567
Pubmed	Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.	WSB1 RAB40B	1.52e-03	18	112	2	18187417
Pubmed	Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.	SCO2 XPC	1.52e-03	18	112	2	26334721
Pubmed	Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.	RAB12 TBC1D15 RAB40B	1.65e-03	72	112	3	16923123
Pubmed	Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation.	HEXB MFSD8	1.70e-03	19	112	2	29514215
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	SPTBN1 FASN AP2B1 DYNC1H1 DNM2	1.74e-03	266	112	5	19380743
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RBBP5 INTS3 TRAPPC13 RBM22 FASN GK PANK4 DYNC1H1 ZMYM3	1.85e-03	857	112	9	25609649
Pubmed	The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.	AP2B1 DNM2	1.88e-03	20	112	2	22103831
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	SPTBN1 PIKFYVE AP2B1 DYNC1H1	1.95e-03	163	112	4	16512683
Pubmed	Genome-wide diet-gene interaction analyses for risk of colorectal cancer.	DPP6 ST8SIA2	2.07e-03	21	112	2	24743840
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	RBBP5 SPTBN1 SSRP1 INTS3 FASN DYNC1H1 ACSL5 DNM2	2.16e-03	711	112	8	33022573
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ADAM9 SPTBN1 PRAG1 AP2B1 DYNC1H1	2.21e-03	281	112	5	28706196
Pubmed	Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).	SLC5A1 FASN	2.28e-03	22	112	2	20965718
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TBC1D15 RBBP5 DHX8 AP2B1 PANK4 DYNC1H1 DNM2	2.29e-03	560	112	7	35241646
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ANKRD35 SPTBN1 SSRP1 TRIP4 DHX8 RBM22 FASN AP2B1 ATP1A3 DYNC1H1 DNM2	2.33e-03	1247	112	11	27684187
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	GAK ADAM9 PIKFYVE TRAPPC13 AP4B1	2.35e-03	285	112	5	34369648
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SCO2 TBC1D15 GAK RBBP5 SPTBN1 NOL6 SSRP1 NCAPG2 FASN AP2B1 PANK4 DYNC1H1	2.36e-03	1440	112	12	30833792
Pubmed	Hereditary Dystonia Overview	POLG MFSD8 ATP1A3	2.39e-03	82	112	3	20301334
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	MYCBP2 FASN ATP1A3 DYNC1H1	2.52e-03	175	112	4	25756610
Pubmed	ETS-dependent regulation of a distal Gata4 cardiac enhancer.	ETV6 ELK4	2.71e-03	24	112	2	22056786
Pubmed	UPF2 is a critical regulator of liver development, function and regeneration.	FASN ACSL5	2.71e-03	24	112	2	20657840
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	FASN GYS2	2.71e-03	24	112	2	27754788
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	RBBP5 SPTBN1 INTS3 DHX8 FASN DYNC1H1 DNM2	2.83e-03	582	112	7	20467437
Pubmed	Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins.	AP2B1 DNM2	2.94e-03	25	112	2	20594957
Pubmed	Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.	MYCBP2 SPTBN1	2.94e-03	25	112	2	12522145
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MYCBP2 ETV6 SSRP1 NCAPG2 RBM22 FASN AP2B1 DYNC1H1 ZMYM3 DNM2	3.02e-03	1103	112	10	34189442
Pubmed	Array MAPPIT: high-throughput interactome analysis in mammalian cells.	WSB1 RAB40B	3.18e-03	26	112	2	19159283
Cytoband	1q32	RBBP5 HHAT ELK4	2.40e-04	49	112	3	1q32
Cytoband	4q28.2	MFSD8 C4orf33	3.83e-04	12	112	2	4q28.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q25	TMC6 OTOP2 FASN LLGL2 RAB40B	9.69e-04	307	112	5	chr17q25
Cytoband	Ensembl 112 genes in cytogenetic band chr4q28	INTU MFSD8 C4orf33	1.05e-03	81	112	3	chr4q28
GeneFamily	ETS transcription factor family	ETV7 ETV6 ELK4	2.08e-04	28	75	3	534
GeneFamily	Glycerol kinases	GK GK2	2.52e-04	6	75	2	568
GeneFamily	WD repeat domain containing	WSB1 IFT140 RBBP5 LLGL2 WDR35 NSMAF	7.63e-04	262	75	6	362
Disease	glycerol kinase deficiency (implicated_via_orthology)	GK GK2	3.83e-05	3	106	2	DOID:0060363 (implicated_via_orthology)
Disease	spinal muscular atrophy (is_implicated_in)	HEXB DPP6	1.90e-04	6	106	2	DOID:12377 (is_implicated_in)
Disease	Mitochondrial Encephalomyopathies	SCO2 FOXRED1	3.53e-04	8	106	2	C0162666
Disease	Oxidative Phosphorylation Deficiencies	FOXRED1 POLG	4.53e-04	9	106	2	C0949856
Disease	Mitochondrial Respiratory Chain Deficiencies	FOXRED1 POLG	4.53e-04	9	106	2	C0949857
Disease	Electron Transport Chain Deficiencies, Mitochondrial	FOXRED1 POLG	4.53e-04	9	106	2	C0949855
Disease	5,6-dihydrothymine measurement	SCO2 TVP23A	4.53e-04	9	106	2	EFO_0800638
Disease	epilepsy (is_implicated_in)	POLG ATP1A3	4.53e-04	9	106	2	DOID:1826 (is_implicated_in)
Disease	Leigh Disease	SCO2 FOXRED1 POLG	6.51e-04	47	106	3	C0023264
Disease	myopathy (implicated_via_orthology)	COL15A1 CLCN2 DNM2	6.93e-04	48	106	3	DOID:423 (implicated_via_orthology)
Disease	Mitochondrial Diseases	SCO2 FOXRED1 POLG	7.36e-04	49	106	3	C0751651
Disease	Short Rib-Polydactyly Syndrome	IFT140 WDR35	9.72e-04	13	106	2	C0036996
Disease	5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement	UGT3A1 CARNS1	9.72e-04	13	106	2	EFO_0800284
Disease	Saldino-Noonan Syndrome	IFT140 WDR35	1.13e-03	14	106	2	C0036069
Disease	Majewski Syndrome	IFT140 WDR35	1.13e-03	14	106	2	C0024507
Disease	asthma	DPP6 COL15A1 NEK10 ETV6 GSAP PIGU PRAG1 PIKFYVE CDK5RAP2	1.56e-03	751	106	9	MONDO_0004979
Disease	diet measurement, colorectal cancer	DPP6 ST8SIA2	2.10e-03	19	106	2	EFO_0008111, MONDO_0005575
Disease	blood aluminium measurement	DPP6 GK2	2.33e-03	20	106	2	EFO_0007575
Disease	erythrocyte measurement	SCO2 RBBP5 TMC6 NOL6 AP2B1	2.39e-03	257	106	5	EFO_0005047
Disease	Primary microcephaly	DPP6 CDK5RAP2	2.82e-03	22	106	2	C0431350
Disease	mortality	GAK POLG DHX8 GALNT17	3.56e-03	173	106	4	EFO_0004352

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVLLGLGGRRWLQKK	MAMDC4	1166	Q6UXC1
LVLLLSGRRNVWKQE	C4orf33	86	Q8N1A6
DGNSLLKAVWLGRLR	ANKRD34C	11	P0C6C1
LKLTNGIWILAELRI	AP2B1	891	P63010
EWQAGIGLILSRARK	GYS2	181	P54840
KQALIWLLGVHGERI	AP4B1	436	Q9Y6B7
LGDILQVAVKLSGWR	CARNS1	156	A5YM72
GVLGLWHVRRRQEKQ	ACVRL1	136	P37023
LERVLARLEWAKAGL	ANKRD35	541	Q8N283
TGIILGLGIWRIVIR	ADGRG7	21	Q96K78
VWRALQALTGPRKLL	DISP2	216	A7MBM2
GQLNGKRDTLWLALR	DISP2	1331	A7MBM2
GVIFGLWTLQKEVRR	ALG12	106	Q9BV10
RLKLLWRVSLPEDGQ	CDK5RAP2	1796	Q96SN8
GELFKIGAKIRWLRD	R3HDM1	1006	Q15032
LRGKKIRLQIWDTAG	RAB12	86	Q6IQ22
LIVNGRRLNVKWGRS	RBM22	291	Q9NW64
ILLDGRRVKLQLWDT	RAB40B	56	Q12829
LIIEGLLNIAWGLRR	RASSF4	51	Q9H2L5
VWLVRELVKSGVLGA	INTS3	146	Q68E01
ERAILLGGLIVVWVG	MFSD8	336	Q8NHS3
WRLALQGGIRLQGIV	NIBAN3	216	Q86XR2
GLAGFLRLWIAVLVI	SLC7A8	116	Q9UHI5
IDWNRELLKRELGLA	PADI4	546	Q9UM07
KIFRIVDPNGLARLW	ETV6	366	P41212
DGEAWIQRPGLIKIR	DGKK	1011	Q5KSL6
IPLKLWERIIAAGSR	LLGL2	396	Q6P1M3
GRLKVALEPQLWELG	LPCAT4	316	Q643R3
GAVIRWLRDNLGIIK	GK3P	326	Q14409
LWKLGSQEGRELLTR	GGNBP1	51	Q5YKI7
VEIRIWGGIKQLLHI	NEK10	326	Q6ZWH5
GKTKWDVLDGVIRRL	NAV3	1946	Q8IVL0
KWPLRSGGLQREQVI	NRG2	166	O14511
DGVALLKVWLRQREL	NOL6	326	Q9H6R4
LKVWLRQRELDKGQG	NOL6	331	Q9H6R4
EGGWISLQDLRKVQR	POLG	1016	P54098
LLLKALQGLRVEWRG	AMH	426	P03971
WYNILRGIGKLAVII	ANO1	786	Q5XXA6
LWRRVLGILGDVNNI	RALGAPA2	931	Q2PPJ7
GEILVIRRGWLTINN	DNM2	516	P50570
WKRVVEGLSLLDLGV	PIGU	41	Q9H490
GRIVIWDFLTRGIAK	RBBP5	46	Q15291
AVIKNAWLAERLGGR	PANK4	746	Q9NVE7
REVWKKGGRLLSVLL	OTOP2	21	Q7RTS6
KDGLRVLNGPLILWR	FANCB	131	Q8NB91
AAKQRIGQLIIWREV	INTU	551	Q9ULD6
LNWLGVTVENGVRRL	HHAT	391	Q5VTY9
GVLLRLQVGEEVWLA	C1QC	206	P02747
VGKELVNWLIRNGHI	PIKFYVE	386	Q9Y2I7
LDWIEGKERNIRALL	GAK	1221	O14976
LGKDVLPWLRAQRAV	GSAP	11	A4D1B5
LLQGIGRRKDLERLW	C3orf84	71	H3BNL1
KIFRVVDPNGLARLW	ETV7	251	Q9Y603
GAVIRWLRDNLGIIE	GK2	326	Q14410
GWARGRQLKLVFLLG	B3GNT4	146	Q9C0J1
LQAEEVARLWGIRKN	ELK4	36	P28324
LRIFGLGWAIILKEK	FBXO15	191	Q8NCQ5
GSLLVRQKAGVQVWL	FCGBP	5336	Q9Y6R7
GILAVLRVLWRGKVL	COMTD1	206	Q86VU5
WCLLQGLRRKVQSLG	FOXRED1	221	Q96CU9
QKREGLIRARIEGWK	GALNT17	221	Q6IS24
AGAVIRWLRDNLGII	GK	331	P32189
RIVLVGLEIWTNGNL	ADAM9	256	Q13443
IGRWLPNGTLKIIDR	ACSL5	526	Q9ULC5
VIRNIIRLREKLGWQ	DNAH14	256	Q0VDD8
LGKGWRELAEKLVRL	MACC1	746	Q6ZN28
KLILRRNPGGWVEKE	ATP1A3	996	P13637
RNLKWLGFRVPLAIV	DYNC1H1	751	Q14204
IITGGEDRQIIFWKL	NSMAF	901	Q92636
LSWDKVRIPGVLQRL	HGSNAT	366	Q68CP4
RNWKGIAIALLVILV	DPP6	91	P42658
WKTLARALGLGVEQL	FASN	896	P49327
PVAVLKANRVWGALR	HEXB	156	P07686
FIRVRDGWKKLQLGE	COL15A1	1166	P39059
FRLIQGLVSKAGWLI	SLC22A2	206	O15244
GDLQWLKIIISCLGR	SLC22A2	426	O15244
LGGAWLALRAEKERL	SCO2	71	O43819
VLLLWRLDQRGRVQG	IFT140	126	Q96RY7
FVQLEGLRKRWEGLV	DHX8	281	Q14562
EVLFWGLRDLKRVNL	OTOF	1136	Q9HC10
ERNRELKTLLSIGGW	OVGP1	86	Q12889
LVIVLAGVGVLVWRR	MR1	311	Q95460
GVLVTLWIIDRLGRK	SVOP	386	Q8N4V2
LLNAVRWLARGQTGK	TCAF2	286	A6NFQ2
LRKWLLVFGNLITAG	SLC18B1	301	Q6NT16
GLLVVTLWRRLAPGK	SLC52A2	61	Q9HAB3
LLPLLWGRERVEGQK	SIGLEC7	6	Q9Y286
RGGKERVEWVNELIL	ST8SIA2	246	Q92186
RSLWRGNGINVLKIA	SLC25A41	146	Q8N5S1
RVVGQILVDKLGLQW	SPATA31E1	1321	Q6ZUB1
WTTLVLGVEELRGLK	MYCBP2	1431	O75592
TLRVRQVKVLGWKDG	MYCBP2	3861	O75592
GKLLIIVLSWIDQRL	OR6T1	41	Q8NGN1
GIWRRVALGHGLKLL	SSRP1	51	Q08945
EAIRQRLADLKQLWG	SPTBN1	1561	Q01082
GLLEIIVILWKSIDR	NCAPG2	621	Q86XI2
RVGEDWIFLVLLGLL	CLCN2	86	P51788
LVLRRGLRIGQLVQW	NEU3	56	Q9UQ49
LLGVVARWLRGARKV	UGT3A1	506	Q6NUS8
ILQLEQGKELWREGR	ZNF705A	56	Q6ZN79
SRRLALLQEQWAGGK	SRA1	126	Q9HD15
GLIQAGLLDRRKLLW	TBC1D15	216	Q8TC07
ILQLEQGKELWREGR	ZNF705G	56	A8MUZ8
IRIGEAKRVLQCLLW	PRAG1	1316	Q86YV5
ILQLEQGKELWREGR	ZNF705D	56	P0CH99
GRLRQAAVLGLVWLL	TMC6	426	Q7Z403
QPWASLLVRGIKRVE	TRIP4	441	Q15650
VGALQELVVQKGWRL	TARBP2	161	Q15633
SVKNVTGRLLVGLRW	TVP23A	76	A6NH52
LLLATGLNNGRIKIW	WSB1	141	Q9Y6I7
GNWKLLAKGLLIRER	XPC	846	Q01831
GRLFILVLIGISIAW	SLC5A1	426	P13866
IGLRLKLGDWFRVLQ	WDR35	771	Q9P2L0
KLGDWFRVLQLLKTG	WDR35	776	Q9P2L0
KLDIVWKTNLGERGR	TRAPPC13	276	A5PLN9
QGKLLETIHWRGQIR	ZMYM3	726	Q14202
LLGLGRKEVSRVQWS	PP2D1	296	A8MPX8
VGLEQLRRLGVLYWK	ADI1	26	Q9BV57
GRIQNEGRIVNWKLI	PCSK1	576	P29120