Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCA1 ERCC6L ATAD5 RAB8B CHD1 RAB8A ABCB4 RAB10 RAB33A CILP2 MDN1 ATAD2B DDX60L ABCC2 GNB1 GNB2 ATP13A4 RAB31 CILP TOR2A SMC2 FIGN DNAH7 GNB4 DDX21	9.48e-05	839	258	25	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCA1 ERCC6L ATAD5 RAB8B CHD1 RAB8A ABCB4 RAB10 RAB33A CILP2 MDN1 ATAD2B DDX60L ABCC2 GNB1 GNB2 ATP13A4 RAB31 CILP TOR2A SMC2 FIGN DNAH7 GNB4 DDX21	9.66e-05	840	258	25	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCA1 ERCC6L ATAD5 RAB8B CHD1 RAB8A ABCB4 RAB10 RAB33A CILP2 MDN1 ATAD2B DDX60L ABCC2 GNB1 GNB2 ATP13A4 RAB31 CILP TOR2A SMC2 FIGN DNAH7 GNB4 DDX21	9.66e-05	840	258	25	GO:0016818
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCA1 SPNS2 ABCB4 MFSD2B	1.12e-04	20	258	4	GO:0046624
GeneOntologyMolecularFunction	kinase activity	CERKL GALK2 HK3 TSSK2 CDKL3 PFKL NEK9 MAP3K4 GK FLT1 CDKL2 PAK5 MAPK14 IGF2R TK2 DYRK1B HASPIN PAK1 PRKCD LTBP1 MAP2K5 MAP3K2 EPHA3	1.57e-04	764	258	23	GO:0016301
GeneOntologyMolecularFunction	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	MBD4 TDG	1.66e-04	2	258	2	GO:0008263
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCA1 ERCC6L ATAD5 RAB8B CHD1 RAB8A ABCB4 RAB10 RAB33A MDN1 ATAD2B DDX60L ABCC2 GNB1 GNB2 ATP13A4 RAB31 TOR2A SMC2 FIGN DNAH7 GNB4 DDX21	1.93e-04	775	258	23	GO:0017111
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	GALK2 HK3 TSSK2 CDKL3 PFKL NEK9 MAP3K4 GK FLT1 CDKL2 PAK5 MAPK14 IGF2R DYRK1B HASPIN PAK1 PRKCD LTBP1 MAP2K5 MAP3K2 EPHA3	3.77e-04	709	258	21	GO:0016773
GeneOntologyMolecularFunction	KDEL sequence binding	KDELR1 KDELR2	4.95e-04	3	258	2	GO:0005046
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 ERCC6L ATAD5 CHD1 ABCB4 MDN1 ATAD2B DDX60L ABCC2 ATP13A4 TOR2A SMC2 FIGN DNAH7 DDX21	6.55e-04	441	258	15	GO:0016887
GeneOntologyMolecularFunction	complement receptor activity	GPR33 CR1 CR2	6.98e-04	14	258	3	GO:0004875
GeneOntologyMolecularFunction	DNA N-glycosylase activity	MBD4 NEIL1 TDG	6.98e-04	14	258	3	GO:0019104
GeneOntologyMolecularFunction	extracellular matrix structural constituent	RELN DMBT1 COL4A5 HSPG2 COL6A3 CILP TECTA HMCN1 LTBP1	7.82e-04	188	258	9	GO:0005201
GeneOntologyMolecularFunction	protein serine kinase activity	TSSK2 CDKL3 NEK9 MAP3K4 CDKL2 PAK5 MAPK14 DYRK1B HASPIN PAK1 PRKCD MAP2K5 MAP3K2	9.33e-04	363	258	13	GO:0106310
GeneOntologyMolecularFunction	mismatch base pair DNA N-glycosylase activity	MBD4 TDG	9.81e-04	4	258	2	GO:0000700
GeneOntologyMolecularFunction	low-affinity IgG receptor activity	FCGR3A FCGR3B	9.81e-04	4	258	2	GO:0019772
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCA1 ABCB4	9.81e-04	4	258	2	GO:0046623
GeneOntologyMolecularFunction	chloride ion binding	NLGN4X NLGN4Y TDG	1.05e-03	16	258	3	GO:0031404
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CERKL GALK2 HK3 TSSK2 CDKL3 PFKL NEK9 MAP3K4 GK FLT1 CDKL2 POLM PAK5 MAPK14 IGF2R TK2 DYRK1B HASPIN PAK1 PRKCD LTBP1 MAP2K5 MAP3K2 EPHA3	1.16e-03	938	258	24	GO:0016772
GeneOntologyCellularComponent	anchoring junction	STARD8 RPLP0 RPS2 ABCB4 RAB10 FAP PTPRA KCND2 MLC1 AFDN ABCC2 GNB2 CD99L2 HSPG2 FLT1 PKP4 ECT2 IGF2R HMCN1 XIRP2 PCDHGA12 SH3PXD2A PAK1 PRKCD IL1RL1 FSCN1 PCDH9	9.11e-05	976	260	27	GO:0070161
GeneOntologyCellularComponent	cell-substrate junction	STARD8 RPLP0 RPS2 ABCB4 RAB10 FAP PTPRA GNB2 CD99L2 HSPG2 FLT1 IGF2R HMCN1 XIRP2 PAK1 IL1RL1	1.47e-04	443	260	16	GO:0030055
MousePheno	abnormal heart right ventricle morphology	ABCA1 NIPBL NOS3 HSPG2 TDG IGF2R XIRP2 SH3PXD2A HAS2 HDAC2 PLCE1	1.18e-05	156	195	11	MP:0003920
Domain	WD40_repeat_dom	LYST DDB1 GTF3C4 EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 UBR4 VPS8 GNB4 EML1 LRBA EIF3I	4.26e-06	297	259	16	IPR017986
Domain	Guanine_nucleotide-bd_bsu	GNB1 GNB2 GNB4	2.58e-05	5	259	3	IPR016346
Domain	-	BIRC6 LYST DDB1 EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 VPS8 GNB4 EML1 LRBA EIF3I	6.80e-05	333	259	15	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	BIRC6 LYST DDB1 EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 VPS8 GNB4 EML1 LRBA EIF3I	7.28e-05	335	259	15	IPR015943
Domain	WD40_repeat	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 VPS8 GNB4 EML1 LRBA EIF3I	1.15e-04	272	259	13	IPR001680
Domain	RCC1	NEK9 HERC3 HERC1 RCBTB1	1.47e-04	20	259	4	PF00415
Domain	WD_REPEATS_2	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 VPS8 GNB4 EML1 LRBA EIF3I	1.49e-04	279	259	13	PS50082
Domain	WD_REPEATS_REGION	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 VPS8 GNB4 EML1 LRBA EIF3I	1.49e-04	279	259	13	PS50294
Domain	RCC1_1	NEK9 HERC3 HERC1 RCBTB1	1.80e-04	21	259	4	PS00625
Domain	RCC1_2	NEK9 HERC3 HERC1 RCBTB1	1.80e-04	21	259	4	PS00626
Domain	RCC1_3	NEK9 HERC3 HERC1 RCBTB1	1.80e-04	21	259	4	PS50012
Domain	AAA	ABCA1 ATAD5 ABCB4 MDN1 ATAD2B ABCC2 TOR2A FIGN DNAH7	1.84e-04	144	259	9	SM00382
Domain	AAA+_ATPase	ABCA1 ATAD5 ABCB4 MDN1 ATAD2B ABCC2 TOR2A FIGN DNAH7	1.84e-04	144	259	9	IPR003593
Domain	NLGN4	NLGN4X NLGN4Y	1.92e-04	2	259	2	IPR030025
Domain	GREB1	GREB1L GREB1	1.92e-04	2	259	2	PF15782
Domain	GREB1	GREB1L GREB1	1.92e-04	2	259	2	IPR028422
Domain	-	NEK9 HERC3 HERC1 RCBTB1	2.17e-04	22	259	4	2.130.10.30
Domain	Reg_chr_condens	NEK9 HERC3 HERC1 RCBTB1	2.17e-04	22	259	4	IPR000408
Domain	RCC1/BLIP-II	NEK9 HERC3 HERC1 RCBTB1	2.60e-04	23	259	4	IPR009091
Domain	WD40	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 GNB4 EML1 LRBA EIF3I	2.80e-04	259	259	12	PF00400
Domain	Gprotein_B	GNB1 GNB2 GNB4	2.94e-04	10	259	3	IPR001632
Domain	-	ABCA1 SAMD9 ERCC6L ATAD5 RAB8B CHD1 RAB8A ABCB4 RAB10 RAB33A MDN1 ATAD2B DDX60L CHST2 ABCC2 RAB31 TOR2A SMC2 FIGN DNAH7 TK2 DDX21 HYDIN	3.05e-04	746	259	23	3.40.50.300
Domain	WD40	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 GNB4 EML1 LRBA EIF3I	3.82e-04	268	259	12	SM00320
Domain	WD_REPEATS_1	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 VPS8 GNB4 EML1 LRBA EIF3I	5.30e-04	278	259	12	PS00678
Domain	ER_ret_rcpt	KDELR1 KDELR2	5.69e-04	3	259	2	IPR000133
Domain	ER_lumen_recept	KDELR1 KDELR2	5.69e-04	3	259	2	PF00810
Domain	ER_LUMEN_RECEPTOR_1	KDELR1 KDELR2	5.69e-04	3	259	2	PS00951
Domain	ER_LUMEN_RECEPTOR_2	KDELR1 KDELR2	5.69e-04	3	259	2	PS00952
Domain	Carboxylesterase_B_CS	NLGN4X NLGN4Y TG	6.80e-04	13	259	3	IPR019819
Domain	Sushi	CSMD3 CFB C7 CR1 CR2	7.53e-04	52	259	5	PF00084
Domain	Quinoprotein_ADH-like_supfam	EML5 WDR90 DMXL2 VPS8 EML1	8.23e-04	53	259	5	IPR011047
Domain	CARBOXYLESTERASE_B_2	NLGN4X NLGN4Y TG	8.57e-04	14	259	3	PS00941
Domain	COesterase	NLGN4X NLGN4Y TG	8.57e-04	14	259	3	PF00135
Domain	CarbesteraseB	NLGN4X NLGN4Y TG	8.57e-04	14	259	3	IPR002018
Domain	Protein_kinase_ATP_BS	TSSK2 CDKL3 MAP3K4 FLT1 CDKL2 PAK5 MAPK14 DYRK1B HASPIN PAK1 PRKCD MAP2K5 MAP3K2 EPHA3	8.75e-04	379	259	14	IPR017441
Domain	CCP	CSMD3 CFB C7 CR1 CR2	8.96e-04	54	259	5	SM00032
Domain	SUSHI	CSMD3 CFB C7 CR1 CR2	1.06e-03	56	259	5	PS50923
Domain	Thioredoxin_8	NHLRC2 NXN	1.13e-03	4	259	2	PF13905
Domain	G8_domain	PKHD1 PKHD1L1	1.13e-03	4	259	2	IPR019316
Domain	G8	PKHD1 PKHD1L1	1.13e-03	4	259	2	PS51484
Domain	G8	PKHD1 PKHD1L1	1.13e-03	4	259	2	SM01225
Domain	G8	PKHD1 PKHD1L1	1.13e-03	4	259	2	PF10162
Domain	Sushi_SCR_CCP_dom	CSMD3 CFB C7 CR1 CR2	1.15e-03	57	259	5	IPR000436
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RPLP0 ACTL6A FLG2 DDB1 GTF3C4 HNRNPH2 FASN MDN1 DMBT1 NIPBL MED12 RANBP2 UBR4 DDX21 HDAC2	3.76e-09	272	267	15	31010829
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	GBF1 RPLP0 RPS2 RPLP0P6 ACTL6A PFKL BIRC6 DDB1 NEK9 GTF3C4 HNRNPH2 FASN MDN1 GNB1 GNB2 MED12 PNP CARM1 RANBP2 HSDL2 UBR4 TPGS2 SMC2 ECT2 ERGIC3 PABPN1 GNB4 EIF3I DDX21 OGA HDAC2	1.27e-08	1257	267	31	37317656
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPS2 CHD1 ACTL6A PFKL BIRC6 DDB1 NEK9 GTF3C4 HNRNPH2 FASN MDN1 VPS33B TUBGCP3 AFDN DDX60L GNB2 NIPBL MED12 PNP GPC1 RANBP2 PKP4 UBR4 SMC2 ECT2 PABPN1 PRKCD EIF3I FSCN1 DDX21	2.22e-07	1353	267	30	29467282
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	GPR155 RAB8B PFKL DDB1 TIAM2 RAB8A RAB10 FASN GK BTG2 EML5 SLC22A8 BHMT2 PKHD1 GNB1 NIPBL PNP SFT2D2 HSPG2 COL6A3 TECTA SMC2 CR1 IGF2R PRKCD	3.70e-07	1016	267	25	19056867
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPLP0 RPS2 CHD1 BIRC6 DDB1 FASN MDN1 ATAD2B AFDN NIPBL MED12 PNP RANBP2 UBR4 IGF2R EIF3I FSCN1 DDX21 HDAC2	8.76e-07	653	267	19	22586326
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	DDB1 GNB1 GNB2 GNB4	1.07e-06	11	267	4	25982117
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	SAMD9 RPLP0 RPS2 ADAM7 PFKL FLG2 RAB10 FASN GNB1 GNB2 TALDO1 GPC1 SMC2 TG PABPN1 SH3PXD2A EIF3I FSCN1 DDX21 MAP3K2 HDAC2	1.27e-06	803	267	21	36517590
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ACAA1 RPLP0 RPS2 SPNS2 NHLRC2 DDB1 GTF3C4 RAB10 FASN MDN1 GNB2 TALDO1 PNP RAB31 GLRX3 UBR4 MUC19 EML1 LRBA HYDIN DNPEP	1.38e-06	807	267	21	30575818
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB1 GNB2 GNB4	1.78e-06	4	267	3	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB1 GNB2 GNB4	1.78e-06	4	267	3	12512701
Pubmed	Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.	RAB8B RAB8A RAB10	1.78e-06	4	267	3	24213529
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	GBF1 ACTL6A BIRC6 DDB1 RAB10 FASN GK TUBGCP3 RANBP2 CDKL2 UBR4 SMC2 IGF2R ERGIC3 PABPN1 EIF3I DDX21 SLC16A10	3.94e-06	657	267	18	36180527
Pubmed	Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption.	KCNF1 AFDN VSNL1 IGF2R	4.34e-06	15	267	4	24090483
Pubmed	Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis.	CFB C1QA CR2	4.42e-06	5	267	3	22566568
Pubmed	The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.	RAB8A PKHD1 PKHD1L1	4.42e-06	5	267	3	20048263
Pubmed	A cohesin-RAD21 interactome.	RPS2 TRAIP PFKL DDB1 HNRNPH2 FASN SMC2 XIRP2 EIF3I IL7R	5.32e-06	208	267	10	22145905
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	ZNF133 RPS2 TIAM2 FBXL5 RAB10 PTPRA VPS33B TUBGCP3 HERC3 CEP126 GNB2 MBD4 HPCAL4 COL4A5 RAB31 MTF2 GLRX3 PKP4 UBR4 MAPK14 PAK1 FSCN1 OGA MAP2K5	7.26e-06	1124	267	24	21900206
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACTL6A DDB1 GTF3C4 MAP3K4 MDN1 COBL HERC1 MED12 FLT1 PCDHB6 XIRP2 WNT10A LRBA HYDIN DNPEP	8.23e-06	497	267	15	36774506
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB1 GNB2 GNB4	8.80e-06	6	267	3	16371464
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB1 GNB2 GNB4	8.80e-06	6	267	3	16884933
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	RPLP0 RPS2 RAB8B PFKL RAB8A RAB10 FASN PTPRA GNB1 GNB2 TALDO1 PNP CR2 CD74 EIF3I FSCN1	9.10e-06	565	267	16	20458337
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	RPLP0 RPS2 PFKL HNRNPH2 RAB10 FASN MDN1 AFDN GNB1 TALDO1 HSPG2 GLRX3 UBR4 IGF2R LRBA EIF3I FSCN1 DDX21	1.07e-05	707	267	18	19738201
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AMER1 GBF1 ERCC6L TSSK2 LYST NEK9 MDN1 DENND1B COBL FNIP1 AFDN PAK5 PTPN21 ECT2 DNAH7 SH3PXD2A ISCU DYRK1B EIF3I MAP3K2	1.31e-05	861	267	20	36931259
Pubmed	Complement facilitates early prion pathogenesis.	CFB C1QA CR2	1.53e-05	7	267	3	11283678
Pubmed	Arthritis critically dependent on innate immune system players.	CFB C1QA CR2	1.53e-05	7	267	3	11869678
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RPLP0 RPS2 RPLP0P6 PFKL DDB1 HNRNPH2 FASN RANBP2 SMC2 NXN DDX21 HDAC2	1.63e-05	344	267	12	36282215
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GBF1 RPLP0 RPS2 CHD1 ACTL6A PFKL DDB1 NEK9 FASN MDN1 VPS33B AFDN CHST2 GNB1 TALDO1 NIPBL RANBP2 HSDL2 UBR4 SMC2 IGF2R PABPN1 PUS1 PRKCD EIF3I DDX21 DNPEP	1.65e-05	1425	267	27	30948266
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	HNRNPH2 GNB1 GNB2 MED12 GNB4	1.95e-05	43	267	5	26487511
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DDB1 NEK9 RAB10 MDN1 AFDN GNB1 GNB2 NIPBL CARM1 RANBP2 DMXL2 PKP4 UBR4 PAK5 SMC2 FRY IGF2R PAK1 EML1 FSCN1 HDAC2	2.03e-05	963	267	21	28671696
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	AMER1 RPLP0 RAB8B ADAM7 TKTL1 LYST RAB8A ABCB4 RAB10 FASN MDN1 KDELR1 PKHD1 ABCC2 GNB1 NIPBL SFT2D2 KDELR2 RANBP2 UBR4 RDH12 PTPN21 SMC2 PCDHGA12 SH3PXD2A DDX21 HDAC2	2.03e-05	1442	267	27	35575683
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB1 GNB2 GNB4	2.44e-05	8	267	3	2328987
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	GBF1 RPLP0 RPS2 ACTL6A NHLRC2 PFKL DDB1 NEK9 RAB10 FASN MDN1 AFDN GNB1 TALDO1 PNP RANBP2 GLRX3 UBR4 SMC2 EIF3I FSCN1 OGA HDAC2	3.11e-05	1149	267	23	35446349
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	ACTL6A DDB1 FASN MDN1 SMC2 DDX21	3.37e-05	79	267	6	26446488
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB1 GNB2 GNB4	3.63e-05	9	267	3	10339615
Pubmed	GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.	RAB8B RAB8A RAB10	3.63e-05	9	267	3	32344433
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	ABCA1 GNB1 GNB2	3.63e-05	9	267	3	16498633
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RPS2 BIRC6 GTF3C4 HNRNPH2 MAP3K4 FASN VPS33B KDELR1 GNB1 GNB2 NIPBL CARM1 RANBP2 UBR4 SMC2 LRBA FSCN1	3.65e-05	704	267	17	29955894
Pubmed	A protein interaction landscape of breast cancer.	GBF1 RPLP0 ACTL6A GTF3C4 GPD1L MDN1 RIN2 MBD4 TALDO1 MTF2 PKP4 UBR4 IGF2R LTBP1 FSCN1 DDX21	3.68e-05	634	267	16	34591612
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GBF1 ERCC6L RPS2 DDB1 NEK9 FASN MDN1 TUBGCP3 CARM1 RANBP2 UBR4 SMC2 LRBA EIF3I DDX21 HDAC2	3.97e-05	638	267	16	33239621
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	GBF1 RPLP0 RPS2 PFKL DDB1 HNRNPH2 RAB8A FASN AFDN DDX60L RANBP2 HSDL2 UBR4 NXN PABPN1 EIF3I DDX21	4.13e-05	711	267	17	33022573
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	GALK2 GBF1 NEK9 HNRNPH2 RAB8A SFT2D2 GLRX3 UBR4 PABPN1 SH3PXD2A PRKCD	4.82e-05	325	267	11	36168628
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB1 GNB2 GNB4	5.16e-05	10	267	3	9733924
Pubmed	Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.	MAP3K4 POU5F1 MAPK14	5.16e-05	10	267	3	21559298
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB1 GNB2 GNB4	5.16e-05	10	267	3	28334111
Pubmed	Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms.	CFB IGF2R CD74	5.16e-05	10	267	3	8706013
Pubmed	Assignment of the protein kinase C delta polypeptide gene (PRKCD) to human chromosome 3 and mouse chromosome 14.	PNP PRKCD	5.87e-05	2	267	2	8188219
Pubmed	The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer.	FASN USP2	5.87e-05	2	267	2	15050917
Pubmed	Exome sequencing in four families with neurodevelopmental disorders: genotype-phenotype correlation and identification of novel disease-causing variants in VPS13B and RELN.	RELN VPS13B	5.87e-05	2	267	2	38771357
Pubmed	Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.	CR1 CR2	5.87e-05	2	267	2	14635039
Pubmed	FcgammaRIIIb and complement component C7 codeficiency in a patient with recurrence of fulminant meningococcal septic shock.	FCGR3B C7	5.87e-05	2	267	2	15889368
Pubmed	Involvement of the lectin pathway of complement activation in antimicrobial immune defense during experimental septic peritonitis.	CFB C1QA	5.87e-05	2	267	2	15322019
Pubmed	Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.	FCGR3A FCGR3B	5.87e-05	2	267	2	26494566
Pubmed	Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.	CFB C1QA	5.87e-05	2	267	2	11283677
Pubmed	Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.	FCGR3A FCGR3B	5.87e-05	2	267	2	23917248
Pubmed	Evidence for gene recombination in FCGR3 gene variants.	FCGR3A FCGR3B	5.87e-05	2	267	2	19320901
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4X NLGN4Y	5.87e-05	2	267	2	23183221
Pubmed	Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.	FCGR3A FCGR3B	5.87e-05	2	267	2	25966632
Pubmed	The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.	FCGR3A FCGR3B	5.87e-05	2	267	2	2967436
Pubmed	Angiotensin II-induced activation of p21-activated kinase 1 requires Ca2+ and protein kinase C{delta} in vascular smooth muscle cells.	PAK1 PRKCD	5.87e-05	2	267	2	16033904
Pubmed	Antibody-mediated glomerulonephritis in mice: the role of endotoxin, complement and genetic background.	CFB C1QA	5.87e-05	2	267	2	12930357
Pubmed	The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.	CR1 CR2	5.87e-05	2	267	2	11981823
Pubmed	Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.	GREB1L GREB1	5.87e-05	2	267	2	29100090
Pubmed	The role and mechanism of asymmetric dimethylarginine in fetal growth restriction via interference with endothelial function and angiogenesis.	NOS3 FLT1	5.87e-05	2	267	2	32215825
Pubmed	Brief Report: HIV-1 Infection Impairs CD16 and CD35 Mediated Opsonophagocytosis of Mycobacterium tuberculosis by Human Neutrophils.	FCGR3B CR1	5.87e-05	2	267	2	27258232
Pubmed	Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.	CR1 CR2	5.87e-05	2	267	2	1708808
Pubmed	Cholesterol efflux regulator ABCA1 exerts protective role against high shear stress-induced injury of HBMECs via regulating PI3K/Akt/eNOS signaling.	ABCA1 NOS3	5.87e-05	2	267	2	36335301
Pubmed	SMC2 knockdown inhibits malignant progression of lung adenocarcinoma by upregulating BTG2 expression.	BTG2 SMC2	5.87e-05	2	267	2	38729325
Pubmed	ZNF143 mediates basal and tissue-specific expression of human transaldolase.	ZNF143 TALDO1	5.87e-05	2	267	2	14702349
Pubmed	TGF-β1 promotes cell migration in hepatocellular carcinoma by suppressing reelin expression.	RELN LTBP1	5.87e-05	2	267	2	30447345
Pubmed	Unusually rapid evolution of Neuroligin-4 in mice.	NLGN4X NLGN4Y	5.87e-05	2	267	2	18434543
Pubmed	Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.	FCGR3A FCGR3B	5.87e-05	2	267	2	22290871
Pubmed	Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.	FCGR3A FCGR3B	5.87e-05	2	267	2	20980704
Pubmed	Hydrogen sulfide triggers late-phase preconditioning in postischemic small intestine by an NO- and p38 MAPK-dependent mechanism.	NOS3 MAPK14	5.87e-05	2	267	2	19168723
Pubmed	Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C delta pathway.	ABCA1 PRKCD	5.87e-05	2	267	2	17325386
Pubmed	Comparative functional evolution of human and mouse CR1 and CR2.	CR1 CR2	5.87e-05	2	267	2	18713965
Pubmed	Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.	FCGR3A FCGR3B	5.87e-05	2	267	2	8940055
Pubmed	Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.	NLGN4X NLGN4Y	5.87e-05	2	267	2	37080762
Pubmed	FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.	FCGR3A FCGR3B	5.87e-05	2	267	2	27059607
Pubmed	Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.	NLGN4X NLGN4Y	5.87e-05	2	267	2	29106499
Pubmed	LncRNA-MAP3K4 regulates vascular inflammation through the p38 MAPK signaling pathway and cis-modulation of MAP3K4.	MAP3K4 MAPK14	5.87e-05	2	267	2	33184917
Pubmed	Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.	NLGN4X NLGN4Y	5.87e-05	2	267	2	26456829
Pubmed	Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.	NLGN4X NLGN4Y	5.87e-05	2	267	2	24104404
Pubmed	[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].	CR1 CR2	5.87e-05	2	267	2	26189291
Pubmed	Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.	FCGR3A FCGR3B	5.87e-05	2	267	2	25154742
Pubmed	Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.	NLGN4X NLGN4Y	5.87e-05	2	267	2	22989184
Pubmed	A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.	FCGR3A FCGR3B	5.87e-05	2	267	2	2525780
Pubmed	FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.	FCGR3A FCGR3B	5.87e-05	2	267	2	12445195
Pubmed	B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.	FCGR3A FCGR3B	5.87e-05	2	267	2	18292508
Pubmed	Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.	FCGR3A FCGR3B	5.87e-05	2	267	2	2521732
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	5.87e-05	2	267	2	20525682
Pubmed	Extracellular calcium-sensing receptor activation induces vitamin D receptor levels in proximal kidney HK-2G cells by a mechanism that requires phosphorylation of p38alpha MAPK.	CASR MAPK14	5.87e-05	2	267	2	17974568
Pubmed	Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.	NOS3 FLT1	5.87e-05	2	267	2	28115513
Pubmed	Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.	FCGR3A FCGR3B	5.87e-05	2	267	2	33163982
Pubmed	Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells.	NOS3 PRKCD	5.87e-05	2	267	2	19188511
Pubmed	eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype.	NOS3 FLT1	5.87e-05	2	267	2	22282588
Pubmed	Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.	NEIL1 TDG	5.87e-05	2	267	2	28827588
Pubmed	Phosphorylation of human fascin inhibits its actin binding and bundling activities.	PRKCD FSCN1	5.87e-05	2	267	2	8647875
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4X NLGN4Y	5.87e-05	2	267	2	24855039
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4X NLGN4Y	5.87e-05	2	267	2	37001827
Pubmed	Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.	CILP2 CILP	5.87e-05	2	267	2	21880736
Interaction	APCS interactions	GK FCGR3A FCGR3B C1QA RHBDD1 TG	3.22e-06	33	255	6	int:APCS
GeneFamily	WD repeat domain containing	LYST EML5 WDR90 HERC1 GNB1 GNB2 DMXL2 DCAF8L2 GNB4 EML1 LRBA EIF3I	1.08e-05	262	177	12	362
GeneFamily	Complement system\|Sushi domain containing	CFB C1QA C7 CR1 CR2	2.51e-05	36	177	5	492
GeneFamily	DNA glycosylases	MBD4 NEIL1 TDG	1.44e-04	11	177	3	1024
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CSMD3 CFB C7 CR1 CR2	2.36e-04	57	177	5	1179
GeneFamily	RAB, member RAS oncogene GTPases	RAB8B RAB8A RAB10 RAB33A RAB31	4.37e-04	65	177	5	388
GeneFamily	Immunoglobulin like domain containing	CILP2 FCGR3A FCGR3B ADGRF5 HSPG2 FLT1 CILP IL1RL1	6.39e-04	193	177	8	594
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF133 ZNF143 SALL3 ZNF274 ZNF337 ZNF551 ZNF841 ZNF345 ZNF843 ZNF251 ZNF416 ZNF34 ZNF792 ZNF500 ZNF74 ZNF420 ZNF853	7.03e-04	718	177	17	28
GeneFamily	F-box and leucine rich repeat proteins	FBXL5 FBXL4 FBXL2	1.08e-03	21	177	3	558
GeneFamily	AAA ATPases	ATAD5 MDN1 ATAD2B FIGN	1.79e-03	53	177	4	413
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST LRBA	3.28e-03	9	177	2	1230
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2C	RELN CSMD3 LRP1B KCND2 MLC1 CEP126 PLEKHH2 ATP13A4 RAB31 NLGN4Y THUMPD2 DNAH7 MAPK14 HAS2 EPHA3	1.22e-06	325	264	15	M39053
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	SALL3 CSMD3 FASN NLGN4X MLC1 CEP126 GPC1 COL4A5 ATP13A4 HSDL2 DNAH7 TNFRSF11B LTBP1 HAS2 PHYHIPL HYDIN EPHA3	2.63e-06	439	264	17	M39054
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	GPR155 CSMD3 NLGN4X MLC1 CEP126 GPC1 COL4A5 ATP13A4 LPAR4 HSDL2 NLGN4Y DNAH7 TNFRSF11B LTBP1 EMP1 HAS2 PHYHIPL HYDIN EPHA3	1.23e-05	600	264	19	M39055
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	TKTL1 NHLRC2 PFKL BIRC6 GREB1L EML5 KCND2 FNIP1 HERC3 HERC1 COL4A5 DMXL2 VSNL1 LPAR4 MTF2 CDKL2 PKP4 PCDHB13 POU5F1 SMC2 ECT2 HMCN1 GREB1 PHYHIPL HDAC2	5.60e-06	776	250	25	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	AMER1 TKTL1 PFKL BIRC6 GREB1L DENND1B EML5 KCND2 FNIP1 HERC1 COL4A5 DMXL2 VSNL1 LPAR4 MTF2 CDKL2 PKP4 PCDHB13 SMC2 DNAH7 CLIP4 HMCN1 GREB1 PCDH9 HDAC2	8.49e-06	795	250	25	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	TKTL1 BIRC6 GREB1L KCND2 FNIP1 HERC1 DMXL2 CDKL2 GREB1	3.06e-05	134	250	9	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	TKTL1 NHLRC2 BIRC6 GREB1L DENND1B KCND2 FNIP1 HERC3 HERC1 ANO4 DMXL2 LPAR4 PKP4 VPS8 PCDHB13 POU5F1 SMC2 ECT2 CLIP4 USP2 RFPL4A GNB4 GREB1	4.40e-05	770	250	23	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500	GREB1L BTG2 KCND2 VSNL1 HMCN1	4.58e-05	34	250	5	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_500
CoexpressionAtlas	DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_1000	GPR155 ACAA1 LGR4 PLEKHH1 GK SLC22A8 BHMT2 PKHD1 TOR2A PHYHIPL	4.69e-05	176	250	10	gudmap_developingKidney_e15.5_S-shaped body_1000_k3
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	TKTL1 NHLRC2 PFKL BIRC6 GREB1L DENND1B KCND2 FNIP1 HERC3 HERC1 COL4A5 DMXL2 LPAR4 CDKL2 PKP4 PCDHB13 SMC2 ECT2 DNAH7 CLIP4 HMCN1 GREB1 PCDH9	5.14e-05	778	250	23	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000	TKTL1 GREB1L KCND2 FNIP1 HERC3 HERC1 DMXL2 CDKL2 ECT2 GREB1	5.41e-05	179	250	10	gudmap_developingGonad_e14.5_ ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	TKTL1 PFKL BIRC6 GREB1L KCND2 FNIP1 HERC1 COL4A5 DMXL2 LPAR4 CDKL2 PKP4 PCDHB13 CLIP4 GREB1	5.95e-05	387	250	15	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	AMER1 PFKL BIRC6 FAP PKHD1 C1QA FNIP1 HERC1 COL4A5 LPAR4 MTF2 PKP4 PCDHB13 SMC2 CLIP3 IGF2R PABPN1 ZNF420 GNB4 HAS2 PCDH9 EPHA3 HDAC2	7.98e-05	801	250	23	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	AMER1 NHLRC2 PFKL BIRC6 GREB1L DENND1B KCND2 FNIP1 HERC1 COL4A5 DMXL2 VSNL1 LPAR4 MTF2 PKP4 PCDHB13 POU5F1 SMC2 ECT2 ZNF420 GREB1 PCDH9 HDAC2	8.44e-05	804	250	23	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000	GPR155 RELN SALL3 ACAA1 DCBLD1 LGR4 PLEKHH1 GK SLC22A8 BHMT2 PKHD1 CHST2 SFT2D2 GPC1 FLT1 TOR2A SMC2 PABPN1 LTBP1 GREB1 LRBA MAP2K5 PHYHIPL	9.60e-05	811	250	23	gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_500	TKTL1 GREB1L KCND2 HERC1 DMXL2 CDKL2 ECT2	1.01e-04	91	250	7	gudmap_developingGonad_e14.5_ ovary_500_k5
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000	AMER1 PFKL FAP COL4A5 LPAR4 PKP4 PCDHB13 SMC2 ZNF420 HAS2 PCDH9 HDAC2	1.33e-04	281	250	12	gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_1000	AMER1 PFKL FAP LPAR4 PKP4 PCDHB13 SMC2 CACNG7 ZNF420 HAS2 PCDH9 HDAC2	1.47e-04	284	250	12	gudmap_developingGonad_e16.5_epididymis_1000_k2
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000	FAP BTG2 KCND2 RIN2 FNIP1 ANO4 HSDL2 ZFAND4 CLIP4 SH3PXD2A LHFPL6 GNB4	1.68e-04	288	250	12	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	ABCA1 FAP BTG2 KCND2 RIN2 FNIP1 ST8SIA4 ANO4 COL6A3 VSNL1 LPAR4 HSDL2 ZFAND4 CLIP4 USP2 CLIP3 HMCN1 SH3PXD2A RCBTB1 LHFPL6 GNB4 HAS2	1.80e-04	791	250	22	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	TKTL1 BIRC6 GREB1L EML5 KCND2 FNIP1 HERC1 DMXL2 VSNL1 LPAR4 CDKL2 SMC2 ECT2 PHYHIPL	1.88e-04	382	250	14	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_200	VSNL1 HMCN1 EMP1 PCDH9	2.29e-04	26	250	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_200
CoexpressionAtlas	DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_500	ABCA1 STARD8 C1QA ADGRF5 ST8SIA4 NOS3 FLT1 LHX6 IL1RL1 IL7R	2.63e-04	217	250	10	gudmap_developingKidney_e15.5_Endothelial cells_500_k4
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_200	COL4A5 LPAR4 PKP4 PCDHB13 HAS2 PCDH9	2.75e-04	76	250	6	gudmap_developingGonad_e16.5_epididymis_200_k4
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_100	FAP KCND2 ANO4 HSDL2	3.07e-04	28	250	4	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k3
CoexpressionAtlas	Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4	RELN ABCA1 SPNS2 CFB ADGRF5 CHST2 NOS3 HSPG2 NXN PKHD1L1 HMCN1 LHFPL6 LTBP1 EMP1 FSCN1	3.09e-04	450	250	15	GSM777063_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	AMER1 ERCC6L LGR4 PFKL GREB1L BTG2 DENND1B KCND2 RIN2 ADGRF5 PLEKHH2 COL6A3 ECT2 DNAH7 CLIP3 IGF2R HMCN1 PRKCD LTBP1 EMP1 FSCN1 PLCE1	3.33e-04	827	250	22	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#3_top-relative-expression-ranked_500	TKTL1 BIRC6 GREB1L FNIP1 HERC1 DMXL2	3.40e-04	79	250	6	gudmap_developingGonad_P2_ovary_500_k3
CoexpressionAtlas	facebase_RNAseq_e9.5_OlfPlac_2500_K3	ERCC6L LGR4 CHD1 ACTL6A CFB GREB1L GPD1L FASN MDN1 EML5 AFDN WDR90 GPC1 CARM1 TROAP FPGS FIGN ECT2 ZNF416 DYRK1B PAK1 PUS1 GREB1 EIF3I HAS2 FSCN1 MAP2K5 PHYHIPL	3.73e-04	1187	250	28	facebase_RNAseq_e9.5_OlfPlac_2500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500	NHLRC2 PFKL BIRC6 GREB1L KCND2 FNIP1 COL4A5 LPAR4 MTF2 PKP4 POU5F1 SMC2 ECT2 HDAC2	3.75e-04	409	250	14	gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	PFKL BIRC6 FAP FNIP1 HERC1 COL4A5 LPAR4 PKP4 PCDHB13 SMC2 HAS2 PCDH9 EPHA3 HDAC2	4.13e-04	413	250	14	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	TKTL1 GREB1L DENND1B KCND2 FNIP1 HERC1 DMXL2 CDKL2 DNAH7 GREB1	4.18e-04	230	250	10	gudmap_developingGonad_e18.5_ovary_1000_k5
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_1000	GPR155 ERCC6L ATAD5 RPS2 ACTL6A EML5 PKHD1 ST8SIA4 PNP VSNL1 LPAR4 PRADC1 TDG SMC2 FIGN ECT2 CACNG7 HMCN1 HASPIN PAK1 HAS2	4.37e-04	787	250	21	gudmap_kidney_e10.5_UretericTip_HoxB7_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	RAB8B C7 CHST2 VSNL1 LPAR4 EMP1	4.44e-04	83	250	6	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500	PFKL COL4A5 LPAR4 PKP4 PCDHB13 SMC2 HAS2 PCDH9	4.51e-04	152	250	8	gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	NHLRC2 BIRC6 GREB1L DENND1B KCND2 FNIP1 HERC1 DMXL2 ECT2 GREB1	4.62e-04	233	250	10	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	AMER1 LGR4 GREB1L BTG2 KCND2 C7 PLEKHH2 COL6A3 VSNL1 CLIP3 HMCN1 EMP1 PCDH9	5.10e-04	373	250	13	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL5 PLEKHH1 RAB10 FASN PTPRA MLC1 CHST2 RAB31 CLIP3 PAK1 FSCN1 PHYHIPL PCDH9	2.24e-10	198	265	13	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 PLEKHH2 CDKL2 PKP4 CASR DNAH7 TNFRSF11B WNT10A EMP1 PCDH9 HYDIN	1.74e-09	190	265	12	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 COBL AFDN PLEKHH2 FBXL2 ATP13A4 CDKL2 CASR POU5F1 DNAH7 HYDIN	2.21e-09	194	265	12	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2orf69 DDB1 PLEKHH1 RAB10 PTPRA CHST2 ANO4 RAB31 RCBTB1 EML1 FSCN1 PCDH9	3.12e-09	200	265	12	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CSMD3 LRP1B PKHD1 ATP13A4 FIGN PKHD1L1 HMCN1 XIRP2 HYDIN PLCE1	1.48e-08	184	265	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CSMD3 LRP1B PKHD1 ATP13A4 FIGN PKHD1L1 HMCN1 XIRP2 HYDIN PLCE1	1.48e-08	184	265	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CSMD3 LRP1B PKHD1 ATP13A4 FIGN PKHD1L1 HMCN1 XIRP2 HYDIN PLCE1	1.48e-08	184	265	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHH1 FASN PTPRA MLC1 CHST2 RAB31 CLIP3 PAK1 FSCN1 PHYHIPL PCDH9	2.84e-08	196	265	11	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAP CILP2 GPC1 KDELR2 COL6A3 VSNL1 RAB31 HMCN1 SH3PXD2A LTBP1 FSCN1	3.16e-08	198	265	11	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAP CILP2 GPC1 KDELR2 COL6A3 VSNL1 RAB31 HMCN1 SH3PXD2A LTBP1 FSCN1	3.16e-08	198	265	11	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCA1 HK3 GK FCGR3A C1QA DMXL2 UBR4 CR1 CD74 IL7R SLC16A10	3.32e-08	199	265	11	667b8b47a5b388506e3177b46747267fad8024f6
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	FAP CILP2 GPC1 COL6A3 VSNL1 HMCN1 SH3PXD2A LTBP1 PHYHIPL EPHA3	1.65e-07	184	265	10	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ABCA1 BHMT2 LPAR4 KIAA1586 HMCN1 PCDHGA12 GNB4 GREB1 PCDH9 EPHA3	1.65e-07	184	265	10	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCA1 FCGR3A GSN-AS1 C1QA ABCC2 DMXL2 RAB31 SH3PXD2A GNB4 SLC16A10	1.83e-07	186	265	10	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCA1 FCGR3A GSN-AS1 C1QA ABCC2 DMXL2 RAB31 SH3PXD2A GNB4 SLC16A10	1.83e-07	186	265	10	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	COVID-19-kidney-Mito-rich_Distal\|kidney / Disease (COVID-19 only), tissue and cell type	TSSK2 LGR4 LRP1B PKHD1 HPCAL4 NLGN4Y PKP4 CASR HMCN1 PCDH9	1.92e-07	187	265	10	2ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPNS2 LYST NOS3 HSPG2 FLT1 PKP4 LHX6 NXN PKHD1L1 GNB4	2.22e-07	190	265	10	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 PLEKHH2 NLGN4Y PKP4 CASR DNAH7 WNT10A EMP1 PCDH9	2.33e-07	191	265	10	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 PLEKHH2 NLGN4Y PKP4 CASR DNAH7 WNT10A EMP1 PCDH9	2.33e-07	191	265	10	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STARD8 SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	2.57e-07	193	265	10	682ce63b73a7d02eef240673db67058d7507f744
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STARD8 SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	2.57e-07	193	265	10	c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	FAP KCND2 C7 PLEKHH2 COL6A3 HMCN1 LTBP1 EMP1 HAS2 EPHA3	2.70e-07	194	265	10	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 COBL GPRC5D COL4A5 ATP13A4 RAB31 OVCH2 PTPN21 NXN PLCE1	2.83e-07	195	265	10	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 HK3 GK FCGR3A C1QA ST8SIA4 DMXL2 RAB31 CR1 SLC16A10	2.96e-07	196	265	10	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPNS2 C7 NOS3 HSPG2 FLT1 PKP4 LHX6 HMCN1 GNB4 IL1RL1	3.11e-07	197	265	10	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	RPLP0 RPS2 CHD1 FAP MDN1 PNP HSPG2 FLT1 PKP4 DDX21	3.26e-07	198	265	10	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA1 FASN C7 PLEKHH2 CARM1 COL6A3 TNFRSF11B SH3PXD2A LTBP1 HAS2	3.41e-07	199	265	10	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPNS2 LYST C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B IL7R	3.41e-07	199	265	10	68412bc39639edc4045437d62548f7101b9f1989
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SPNS2 C7 NOS3 HSPG2 FLT1 PKP4 LHX6 PKHD1L1 TNFRSF11B EMP1	3.57e-07	200	265	10	cb00760ae75c30b1cb8526534aabd4ffc7c21000
ToppCell	distal-Endothelial-Vein-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPNS2 BHMT2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	3.57e-07	200	265	10	ff88d28162e0231d5dac0e0c6bec98fa8da58a23
ToppCell	distal-2-Endothelial-Vein\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPNS2 BHMT2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B HAS2	3.57e-07	200	265	10	2785225956d2422acab90e99b7debe3709cf3308
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAP BHMT2 C7 PLEKHH2 COL6A3 CILP HMCN1 LHFPL6 EMP1 HAS2	3.57e-07	200	265	10	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CERKL GREB1L MDN1 TUBGCP3 CHST2 NLGN4Y LHX6 TNFRSF11B ZNF420	3.75e-07	154	265	9	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B PKHD1 PLEKHH2 PAK5 MUC19 TECTA PKHD1L1 HMCN1 HYDIN	5.17e-07	160	265	9	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B PKHD1 PLEKHH2 PAK5 MUC19 TECTA PKHD1L1 HMCN1 HYDIN	5.17e-07	160	265	9	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM7 CSMD3 LRP1B PKHD1 DMBT1 ABCC2 TECTA PKHD1L1 HYDIN	5.74e-07	162	265	9	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HK3 GK FCGR3A C1QA ST8SIA4 RAB31 DOK2 CR1 SLC16A10	7.79e-07	168	265	9	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HK3 GK FCGR3A C1QA ST8SIA4 RAB31 DOK2 CR1 SLC16A10	7.79e-07	168	265	9	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	ABCA1 COBL AFDN GPRC5D ATP13A4 OVCH2 PTPN21 NXN PLCE1	1.04e-06	174	265	9	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SALL3 NLGN4X COBL COL4A5 TROAP PCDHB13 FIGN ECT2 PCDHGA12	1.09e-06	175	265	9	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GREB1L PLEKHH1 PLEKHH2 VSNL1 FIGN DNAH7 TNFRSF11B PHYHIPL HYDIN	1.09e-06	175	265	9	284fdc7a9d303636a637041846850d19d114861a
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SALL3 NLGN4X COBL COL4A5 TROAP PCDHB13 FIGN ECT2 PCDHGA12	1.09e-06	175	265	9	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SALL3 NLGN4X COBL COL4A5 TROAP PCDHB13 FIGN ECT2 PCDHGA12	1.09e-06	175	265	9	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SALL3 NLGN4X COBL COL4A5 TROAP PCDHB13 FIGN ECT2 PCDHGA12	1.09e-06	175	265	9	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	Mesenchymal_cells-Osteoblasts\|Mesenchymal_cells / Lineage and Cell class	C2orf69 SPNS2 DCBLD1 FAP GPC1 KDELR2 FIGN NXN TG	1.59e-06	183	265	9	d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPNS2 GREB1L PKHD1 PLEKHH2 FIGN TNFRSF11B PHYHIPL HYDIN	1.60e-06	136	265	8	82b1d6d839c0d0c68e0960549f688138479defcc
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COBL AFDN GPRC5D COL4A5 ATP13A4 OVCH2 PTPN21 NXN PLCE1	1.66e-06	184	265	9	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COBL AFDN GPRC5D COL4A5 ATP13A4 OVCH2 PTPN21 NXN PLCE1	1.66e-06	184	265	9	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PLEKHH2 COL4A5 NXN TNFRSF11B CLIP4 FRY EPHA3 PLCE1	1.74e-06	185	265	9	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAP CILP2 COL6A3 CILP CLIP3 HMCN1 LTBP1 HAS2 EPHA3	1.74e-06	185	265	9	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LGR4 NLGN4X C7 COL6A3 CILP LHFPL6 LTBP1 PCDH9 EPHA3	1.74e-06	185	265	9	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PLEKHH2 COL4A5 NXN TNFRSF11B CLIP4 FRY EPHA3 PLCE1	1.74e-06	185	265	9	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 LRP1B PKHD1 FBXL2 NLGN4Y CASR WNT10A EML1 PCDH9	1.90e-06	187	265	9	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 LRP1B PKHD1 FBXL2 NLGN4Y CASR WNT10A EML1 PCDH9	1.90e-06	187	265	9	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	SPNS2 RIN2 ADGRF5 NOS3 HSPG2 FLT1 TECTA PKHD1L1 HMCN1	1.90e-06	187	265	9	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 LRP1B PKHD1 FBXL2 NLGN4Y CASR WNT10A EML1 PCDH9	1.90e-06	187	265	9	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 LGR4 LRP1B LYST PKHD1 HPCAL4 NLGN4Y CASR HMCN1	1.90e-06	187	265	9	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Control-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	GVINP1 RIN2 ADGRF5 HERC3 CHST2 FLT1 FRY IL1RL1 EML1	1.98e-06	188	265	9	88b3415e33db81726dd29c1f50c886e057af50a0
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	RIN2 ADGRF5 CHST2 FLT1 FRY LHFPL6 CD74 IL1RL1 EML1	1.98e-06	188	265	9	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 COBL FBXL2 NLGN4Y CASR WNT10A EMP1 HYDIN	2.07e-06	189	265	9	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND1B PKHD1 PLEKHH2 COL4A5 PKP4 CASR FRY LRBA PCDH9	2.07e-06	189	265	9	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAP ADGRF5 HSPG2 FIGN TNFRSF11B LHFPL6 LTBP1 EMP1 HAS2	2.07e-06	189	265	9	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAP C7 COL6A3 LPAR4 CILP LHFPL6 LTBP1 GREB1 EPHA3	2.07e-06	189	265	9	d531399749409d614adca13d181830c6e3287508
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 COBL FBXL2 NLGN4Y CASR WNT10A EMP1 HYDIN	2.07e-06	189	265	9	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6L ATAD5 COBL TROAP DOK2 SMC2 ECT2 HASPIN EPHA3	2.16e-06	190	265	9	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	LGR4 ADH7 FAM118A GPC1 COL4A5 VSNL1 NLGN4Y LHX6 WNT10A	2.26e-06	191	265	9	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SPNS2 BHMT2 ADGRF5 COL4A5 HSPG2 LHX6 HMCN1 PCDHGA12 EML1	2.26e-06	191	265	9	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	SPNS2 RIN2 ADGRF5 NOS3 HSPG2 FLT1 PKP4 PKHD1L1 EML1	2.26e-06	191	265	9	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	SPNS2 RIN2 ADGRF5 NOS3 HSPG2 FLT1 PKP4 PKHD1L1 EML1	2.36e-06	192	265	9	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 COBL AFDN PLEKHH2 FBXL2 CASR POU5F1 DNAH7	2.46e-06	193	265	9	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 PKHD1 COBL AFDN PLEKHH2 FBXL2 CASR POU5F1 DNAH7	2.46e-06	193	265	9	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	LGR4 FAP NLGN4X C7 PLEKHH2 COL6A3 CILP HAS2 EPHA3	2.57e-06	194	265	9	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	HK3 LYST RAB10 FCGR3A FCGR3B C1QA DMXL2 RAB31 PAK1	2.57e-06	194	265	9	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C7 CHST2 PLEKHH2 COL6A3 NLGN4Y HMCN1 LHFPL6 EMP1 PLCE1	2.57e-06	194	265	9	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BEST2 CSMD3 LRP1B PKHD1 DMBT1 ABCC2 TECTA HYDIN	2.59e-06	145	265	8	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	distal-Hematologic-Plasma-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRSS16 TIAM2 EML5 GPRC5D TBCEL CR2 PKHD1L1 WNT10A GREB1	2.68e-06	195	265	9	4280a5bc5ed9bb12e278b182e0be6cb88fa83d83
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADGRF5 C7 NOS3 PNP HSPG2 FLT1 LHX6 FRY HMCN1	2.68e-06	195	265	9	4658fb197657d7692ee344ae76b11b0210c418ba
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 LRP1B PKHD1 COBL AFDN PKP4 CASR DNAH7 LRBA	2.68e-06	195	265	9	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STARD8 SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 TNFRSF11B EMP1	2.68e-06	195	265	9	53b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 HK3 FCGR3A C1QA DMXL2 RAB31 CR1 CD74 SLC16A10	2.79e-06	196	265	9	1b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR4 CFB C7 COL4A5 COL6A3 HMCN1 LHFPL6 LTBP1 EMP1	2.79e-06	196	265	9	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR4 CFB C7 COL4A5 COL6A3 HMCN1 LHFPL6 LTBP1 EMP1	2.79e-06	196	265	9	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	distal-Hematologic-Plasma\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRSS16 TIAM2 EML5 GPRC5D TBCEL CR2 PKHD1L1 WNT10A GREB1	2.79e-06	196	265	9	2a11dc1e51c64af7705e1622a9da583a6634c563
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RAB8B LYST GK BTG2 FCGR3B DDX60L CR1 MAPK14 IGF2R	2.91e-06	197	265	9	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPR155 NLGN4X COBL GPC1 FIGN HMCN1 PHYHIPL PCDH9 PLCE1	2.91e-06	197	265	9	b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 COBL COL4A5 ATP13A4 RAB31 OVCH2 PTPN21 NXN PLCE1	2.91e-06	197	265	9	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CHD1 RAB10 GK FCGR3A DMXL2 RAB31 CR1 MAP3K2 SLC16A10	2.91e-06	197	265	9	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAB8B CHD1 LYST FBXL5 GK BTG2 FCGR3B DDX60L CR1	2.91e-06	197	265	9	3cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN5 ADGRF5 NOS3 HSPG2 FLT1 PKP4 LHX6 EMP1 FSCN1	2.91e-06	197	265	9	b18f2c14d6720f6ae8520c0800356f4a57393ad3
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FAP C7 PLEKHH2 COL6A3 HMCN1 SH3PXD2A LTBP1 VPS13B EPHA3	2.91e-06	197	265	9	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	ZNF143 HK3 FCGR3A ADGRF5 C7 ST8SIA4 RANBP2 FLT1 CR1	3.03e-06	198	265	9	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	3.03e-06	198	265	9	3ae1e2b4ca77b94eaa24a8c990780aff47dface6
ToppCell	NS-critical-d_0-4-Myeloid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA1 RAB8B LYST FBXL5 GK FCGR3A FCGR3B DDX60L DMXL2	3.03e-06	198	265	9	72d51284d267f102c26f0ae8279ee9e11e69c7e3
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	3.03e-06	198	265	9	71ee440b1ac566db63d0b415c50a0ad064d14f15
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHH1 FASN MLC1 RAB31 CLIP3 PAK1 FSCN1 PHYHIPL PCDH9	3.03e-06	198	265	9	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	ZNF143 HK3 FCGR3A ADGRF5 C7 ST8SIA4 RANBP2 FLT1 CR1	3.03e-06	198	265	9	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	ZNF143 HK3 FCGR3A ADGRF5 C7 ST8SIA4 RANBP2 FLT1 CR1	3.03e-06	198	265	9	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	NLGN4X C7 PLEKHH2 COL6A3 FIGN HMCN1 LHFPL6 PCDH9 EPHA3	3.03e-06	198	265	9	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 C7 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 TNFRSF11B EMP1	3.03e-06	198	265	9	fb70a649e4e2edb32967328c1085dc5999c29a33
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STARD8 SPNS2 NOS3 HSPG2 FLT1 LHX6 PKHD1L1 GNB4 EML1	3.16e-06	199	265	9	3a4deea6e11a0555d27497b7c9983350797aac69
Disease	Secondary Biliary Cholangitis	ABCB4 DENND1B ABCC2 NOS3 MAPK14 IL7R	1.55e-06	42	254	6	C0238065
Disease	Biliary cirrhosis	ABCB4 DENND1B ABCC2 NOS3 MAPK14 IL7R	1.55e-06	42	254	6	C0023892
Disease	Biliary Cirrhosis, Primary, 1	ABCB4 DENND1B ABCC2 NOS3 MAPK14 IL7R	1.55e-06	42	254	6	C4551595
Disease	Dyggve-Melchior-Clausen disease (implicated_via_orthology)	RAB8B RAB8A RAB10	2.51e-06	4	254	3	DOID:0111167 (implicated_via_orthology)
Disease	Primary biliary cirrhosis	ABCB4 DENND1B ABCC2 NOS3 MAPK14 IL7R	3.06e-06	47	254	6	C0008312
Disease	Smith-McCort dysplasia (implicated_via_orthology)	RAB8B RAB8A RAB10	6.22e-06	5	254	3	DOID:0060247 (implicated_via_orthology)
Disease	Liver Cirrhosis, Experimental	RAB8B PLEKHH1 GK SLC22A8 FCGR3A C1QA C7 ABCC2 NOS3 RAB31 SMC2 ECT2 FRY IGF2R LHFPL6 CD74 PRKCD LTBP1 EMP1 IL7R	1.42e-05	774	254	20	C0023893
Disease	Colorectal Carcinoma	ABCA1 STARD8 SALL3 HK3 OTOP2 CHD1 CSMD3 ABCB4 NLGN4X PKHD1 ABCC2 ST8SIA4 FBXL2 FPGS NXN ERGIC3 GNB4 EPHA3	4.26e-05	702	254	18	C0009402
Disease	Down syndrome (biomarker_via_orthology)	RPLP0 RPLP0P6	7.38e-05	2	254	2	DOID:14250 (biomarker_via_orthology)
Disease	level of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum	FCGR3A FCGR3B	7.38e-05	2	254	2	OBA_2040305
Disease	ascending aortic diameter	ATAD5 COL6A3 FIGN HMCN1 HAS2 HYDIN PLCE1	2.19e-04	140	254	7	EFO_0021787
Disease	Lupus Vasculitis, Central Nervous System	FCGR3A FCGR3B	2.20e-04	3	254	2	C0752332
Disease	Lupus Meningoencephalitis	FCGR3A FCGR3B	2.20e-04	3	254	2	C0752334
Disease	Neuropsychiatric Systemic Lupus Erythematosus	FCGR3A FCGR3B	2.20e-04	3	254	2	C0752335
Disease	cholestasis (is_implicated_in)	ABCB4 VPS33B	2.20e-04	3	254	2	DOID:13580 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGALRNLVFGKSTDE	PKP4	591	Q99569
CGFSSNGLIESVELR	TDG	356	Q13569
GRGVLADGTTRFTCK	ADH7	131	P40394
AAGNFATKCIRVSST	AFDN	51	P55196
SGCAETLFGLKNIFS	ATAD5	1456	Q96QE3
IEGCSFTGFKANELT	FAM227B	146	Q96M60
FLLRKNSCVSEASTG	BEST2	416	Q8NFU1
ACAKGLVSQVFLTGT	CDY1	456	Q9Y6F8
TSGTRKSENLRGCDL	BIRC6	1281	Q9NR09
FILVGSSTRICQADG	CSMD3	3321	Q7Z407
ASFTLIGFSKGCVVL	C2orf69	256	Q8N8R5
GQVRRSLGFCDTTNK	C1QA	181	P02745
SLGFCDTTNKGLFQV	C1QA	186	P02745
ACTTGVLQTLTLFKG	DNPEP	456	Q9ULA0
ASISTCNGLRGFFRI	ADAM7	121	Q9H2U9
RKSLCLAGSIFSFGI	ATP13A4	31	Q4VNC1
NLVCFDKTGTLTRDG	ATP13A4	481	Q4VNC1
RCKQKVIFGSGTVTF	CASR	961	P41180
ILVSQSGITKLCDFG	CDKL3	131	Q8IVW4
SGITKLCDFGFARTL	CDKL3	136	Q8IVW4
ALFGLQFTVSAGKCT	GVINP1	1501	Q7Z2Y8
ALRSSGTAAAKGERC	GSG1	121	Q2KHT4
FGTALCKVFNGTLSL	GPR33	96	Q49SQ1
CVGSSLFLKNQLGTG	ABCA1	1111	O95477
LCKTAVLTAFANGRS	ACTL6A	151	O96019
TKRSSCLVTYQGGGE	AMER1	356	Q5JTC6
NRLFSCGADGTLKTR	DMXL2	3006	Q8TDJ6
TDKCSRLIVSASGIF	ANO4	496	Q32M45
IAGQKVGTLRFCGTT	CLIP4	291	Q8N3C7
CAKQISFNGSEGRRS	CHD1	1076	O14646
KIVDFGSSCQLGQRI	DYRK1B	256	Q9Y463
GSEGRLLTFCRAASV	POLM	171	Q9NP87
CRQCVFATTTKRGGA	MTF2	151	Q9Y483
QEIASIRKACVFGTS	RCBTB1	16	Q8NDN9
GDSGVGKTCVLFRFS	RAB10	16	P61026
RTAENFRALCTGEKG	RANBP2	3091	P49792
VIGDSNVGKTCLTFR	RAB33A	41	Q14088
NVGKTCLTFRFCGGT	RAB33A	46	Q14088
GRFSSGITGCVKNLV	HSPG2	4346	P98160
LGDTGVGKSSIVCRF	RAB31	11	Q13636
DSGVGKTCVLFRFSE	RAB8A	16	P61006
DSGVGKTCLLFRFSE	RAB8B	16	Q92930
CTQGEKFRVAVSLGT	ECT2	221	Q9H8V3
VFKLDCNSGTISTIG	PCDHGA12	291	O60330
VDARFKTFGCGSAIA	ISCU	86	Q9H1K1
KEAGERTFRCSQAGL	LRRC3C	56	A6NJW4
SCSLEGVEIKGGSFR	CFB	36	P00751
LTSDGRIKLSDFGFC	PAK5	576	Q9P286
SIRKFFAGGVCRTNV	RDH12	21	Q96NR8
EARDAGTFSGKCTVL	PCDHB13	321	Q9Y5F0
KGNRFFLSGATTLVC	EMP1	91	P54849
GRCIASQLGATFFKI	FIGN	536	Q5HY92
RGCIGVGDSSLKTFA	FBXL2	86	Q9UKC9
SRIREQKLGSSCSGS	FLG2	256	Q5D862
KVTFSFEAGRRCVSG	DOK2	206	O60496
SSGFGTALLARKECL	MDN1	1651	Q9NU22
GQIAVCSFGESVKLL	MDN1	5421	Q9NU22
ICALSVTSRGSFEQK	HPCAL4	86	Q9UM19
LGVKTTGFIRCNSTS	LRP1B	2636	Q9NZR2
LVFGGCVEKSSVSRN	NEIL1	21	Q96FI4
CDGTFLLTQSGKVLA	NEK9	541	Q8TD19
SARFTCTLRSGINVG	IGLV5-39	36	A0A0G2JS06
TDGFCQAGKDLRLVS	GREB1	91	Q4ZG55
KENIFGESRASTFCG	PRKCD	496	Q05655
ASKSRSCGEVRQIYG	GPC1	26	P35052
ARIFCKGQVSTATFL	GPD1L	241	Q8N335
TSTQAKGLGNFVSRF	GPR155	66	Q7Z3F1
CGFSKQILEILNSTG	GLRX3	261	O76003
GSVCAAFDTKTGLRV	MAPK14	36	Q16539
QIFSGGDQTFVLCSK	HERC3	366	Q15034
FGDTLCKISGTAFLT	LPAR4	106	Q99677
TSRKETFLKGNCLNG	ATAD2B	1256	Q9ULI0
SCSVGANGKRDVLFL	LINC02872	46	A2RU37
DFVPATCNTKFSLRG	KIAA1109	571	Q2LD37
FVISTDGSVRACGKG	HERC1	416	Q15751
GRARGSKCFLLTSNA	DDX58	731	O95786
NDDVGKRAGSVCTFL	DDX60L	1116	Q5H9U9
SRVGKQSFIITLGCN	CARM1	91	Q86X55
SCQIIQFLKGSREGT	DCAF8L2	501	P0C7V8
FSDCKIQNGTSGIRF	HNRNPH2	31	P55795
AFCSDGANTILGRKS	KIAA1586	386	Q9HCI6
AAKTQLGRCFQETIG	LTBP1	551	Q14766
VNTRGQVKLCDFGVS	MAP2K5	291	Q13163
FLSGRKSISFVGCGI	OR2V1	86	Q8NHB1
FLSGRKSISFVGCGI	OR2V2	86	Q96R30
FLQQGKSISFSGCLA	OR4Q3	86	Q8NH05
QSAEGRRKALSTCGS	OR4S2	226	Q8NH73
RCKVEGSSLTTFDGV	MUC19	816	Q7Z5P9
NTFVGGCDTLSKRSS	PCDH9	971	Q9HC56
GTIIGSARCKAFTTR	PFKL	81	P17858
TLEDFRVKTCGGATV	ERGIC3	16	Q9Y282
VDICRKFGAQGSRLT	GALK2	386	Q01415
DFGASKRLQTICLSG	MAP3K2	501	Q9Y2U5
GVNSGRLVACITTLF	NIPBL	1996	Q6KC79
IAGKIFGSICSLSGV	KCND2	381	Q9NZV8
GLFCTFSVNGKLQAT	LRBA	2761	P50851
CTVFITGASRGIGKA	HSDL2	11	Q6YN16
SCKRQLSTGEEFGLV	LHX6	161	Q9UPM6
SGCKVAGFLAVFSSE	LGR4	616	Q9BXB1
FTKLSGACALGISTL	MFSD2B	421	A6NFX1
FDKCQEATAGFTIGR	MED12	441	Q93074
GRTFVSGACDASIKL	GNB2	196	P62879
CGITSVAFSKSGRLL	GNB4	271	Q9HAV0
RSLDRSFGLVGQSFC	TUBGCP3	311	Q96CW5
FGRDSSLTCLAGNVS	IL7R	361	P16871
TGAGKSSLTNCLFRI	ABCC2	1336	Q92887
SFRKLNCLDISGTGL	LRRC42	256	Q9Y546
FLTVGCREGKVFAAS	RFPL4A	186	A6NLU0
QIALVERGGCSFLSK	PRADC1	86	Q9BSG0
ERGGCSFLSKTRVVQ	PRADC1	91	Q9BSG0
SFFQALGITTKISRG	RPLP0	136	P05388
RCVVTFLQSEDGSGK	HK3	891	P52790
TTDGFCQAGKDLRLV	GREB1L	116	Q9C091
SQLGKPVSFGTFRRC	LHFPL6	36	Q9Y693
EGNIASGKTTCLEFF	TK2	56	O00142
ELTKGTCLRFAGSGN	NHLRC2	381	Q8NBF2
KLSEGQRLSSLTFGC	PLEKHH2	181	Q8IVE3
LGVLFGKVFSQTTIC	POU5F1	171	Q01860
SRKCGILSSGNNLFF	RELN	2191	P78509
AGRYSCKAINIAGTS	HMCN1	1426	Q96RW7
SGCGKSTVVQLLERF	ABCB4	1071	P21439
TDSAGALGTLRFCVF	NOS3	636	P29474
RFRTDSGCYATTGLK	PTPN21	1031	Q16825
LLACTLISGGAFNKV	OTOP2	41	Q7RTS6
GSVKLTDFGFCAQIT	PAK1	401	Q13153
KRVTIFGSGAGASCV	NLGN4Y	246	Q8NFZ3
GSVNRVTILCDKFSG	PABPN1	196	Q86U42
QSAEGRRKVFSTCGA	OR5T1	241	Q8NG75
QSGVVKLCDFGFART	CDKL2	136	Q92772
AARAGFKRTTGVCIA	GSN-AS1	146	Q9NRJ2
TKSFLFVGCGETLRD	FAM118A	226	Q9NWS6
SACFGKGTQFLAAVL	IL1RL1	236	Q01638
LSRGKVDFATIQCGQ	HYDIN	1701	Q4G0P3
INFGALICGTRKSTT	HYDIN	3176	Q4G0P3
SSTFKGICQRDAILT	KLRF2	186	D3W0D1
LVKAGASIVGVNCRF	BHMT2	196	Q9H2M3
FGFTLKGSKQIRCNA	CR2	381	P20023
GCRKVTGTLDANRSS	FSCN1	396	Q16658
CLAFSLATLVQRGSG	CD99L2	11	Q8TCZ2
SFVCDEGFRLKGRSA	CR1	1736	P17927
TRLFVSGACDASAKL	GNB1	196	P62873
CGITSVSFSKSGRLL	GNB1	271	P62873
ASNLVKLVRGCVSFS	GPRC5D	111	Q9NZD1
ISVAGFSRFLKVCGS	FBXL4	361	Q9UKA2
GSAKVQSGFICTNRK	CEP126	761	Q9P2H0
KVFTARTGSSICGSL	FNIP1	161	Q8TF40
KTNSAVRTCGFDFGG	EIF3I	91	Q13347
QDLGTAGSCLRRFST	COL4A5	1501	P29400
LTRAGILTFCVGASQ	COL6A3	766	P12111
INTKSFGGQCRKVFS	C7	156	P10643
RVSVGQSCGFSGKQS	COBL	986	O75128
FKQGGSTCIRLGDST	DNAH7	3056	Q8WXX0
VGLIKSSFASCLRGN	HAS2	416	Q92819
SARGIICGLTQFTNK	GK	381	P32189
GTQGCFSKSLLLSAS	CEACAM19	6	Q7Z692
DVCTFSTAGKLLRFG	CERKL	331	Q49MI3
SRALTLLSSVFGACG	CACNG7	6	P62955
SNLVCKVSDFGLSRV	EPHA3	756	P29320
SQPCVLGRESFASGK	BTN2A1	371	Q7KYR7
FTGSKCGVITAYTNR	LYST	3581	Q99698
SAQFGATAGTECRKS	MBD4	71	O95243
FCRGLVGSKNVSSET	FCGR3B	171	O75015
LSSTGKRRATGQDSC	HASPIN	286	Q8TF76
GKGSTCAFTECILRS	FPGS	106	Q05932
KTLRIFVEASLNGGC	GBF1	1416	Q92538
RAVTCIAFSKSNGGT	EML1	326	O00423
GVCSVSFSATGKLLL	EML5	1471	Q05BV3
STSGCFSKDIVGLRT	FBXL5	516	Q9UKA1
KATFAGGSRDGVITC	FRY	2801	Q5TBA9
ESKCSRGALYTGFSI	CD74	41	P04233
SRSCAGISGKSQVLF	KDELR1	26	P24390
LLDGQKTGTLRFCGT	CLIP3	301	Q96DZ5
KTGTLRFCGTTEFAS	CLIP3	306	Q96DZ5
GSLSDKRFLFTSNGC	DCBLD1	241	Q8N8Z6
LIAQARTGTGKTFSF	DDX21	226	Q9NR30
SLSGDRLGCFNLTVK	HDAC2	266	Q92769
FCRGLFGSKNVSSET	FCGR3A	171	P08637
LGCRVFTTVGSAEKR	FASN	1691	P49327
LIARVCDGARGSFTS	DMBT1	2076	Q9UGM3
IESKQRFGFCRLTSG	DENND1B	76	Q6P3S1
RTVLAVFGKGCLSSS	SLC22A8	411	Q8TCC7
SKRVGSFLSTCIIAG	SLC15A5	376	A6NIM6
FGCTICGRAFTTKGN	SALL3	1141	Q9BXA9
TRSCAGISGKSQLLF	KDELR2	26	P33947
KRVTIFGSGAGASCV	NLGN4X	246	Q8N0W4
CGLRVFGFSLITNKV	PNP	231	P00491
VTCSGAFKEGSLRII	DDB1	376	Q16531
FDFACQGSLLGTLKT	ERCC6L	271	Q2NKX8
AGRTGTFCALSTVLE	PTPRA	736	P18433
VCLTGGSETNEFKFL	PCDHB6	751	Q9Y5E3
LLGSKSISFGGCLTQ	OR1A1	86	Q9P1Q5
VRTRGGVGKAFSTCS	OR1N1	226	Q8NGS0
LSERKTISFSGCAVQ	OR13C9	86	Q8NGT0
LTSSGLIKLGDFGCS	MAP3K4	1471	Q9Y6R4
LVSRLCSGSFKSGYV	MEI4	66	A8MW99
VQSSIAFLCGKTLGT	IGF2R	126	P11717
CLLSGTKGASFGRLQ	IGF2R	1856	P11717
ISGKLEGIFFSCSTE	PHYHIPL	221	Q96FC7
SFFQALGITTKISRG	RPLP0P6	136	Q8NHW5
FLTVGCREGKVFAAS	RFPL4AL1	186	F8VTS6
QLFLGTVCKGDFTRV	TRMT2B	41	Q96GJ1
TAICRAGRGGFKDTT	ACAA1	46	P09110
KRSCAVGFSGVLFAL	RHBDD1	136	Q8TEB9
STRIKGFIACFAIGI	SFT2D2	31	O95562
QASGKIRLLDVGSCF	BMT2	161	Q1RMZ1
IFLDATTGKVVCRNG	NXN	136	Q6DKJ4
SSLKANGSRGAFCEV	OGA	866	O60502
FNKTSGKSSCEGIRQ	PLCE1	1716	Q9P212
VTGGFNSKNRCDART	PUS1	186	Q9Y606
TTISLSQCEKFLGIG	SAMD9	931	Q5K651
GTCRGFQATVSFIPK	OVCH2	531	Q7RTZ1
VETFGFQGKALSSLC	PMS2P2	166	O95744
DGRSQVSISCFGKTF	PTTG3P	36	Q9NZH4
NRRFKTCAVVGNSGI	ST8SIA4	136	Q92187
AGQFRTALELCSKGA	SPATA16	196	Q9BXB7
KDRGAGLLQSVFICS	SPNS2	136	Q8IVW8
CNDSGGSVFELTFKR	VPS8	261	Q8N3P4
SGLDNCTRISGFLAF	PKHD1	3136	P08F94
YSCGTAAIRGTKELG	SPSB3	131	Q6PJ21
KGQFTTVRKSGQCSG	PRORP	336	O15091
KASSFRSCRGFLSAG	STARD8	161	Q92502
QKFGREVDGFTATCA	SPTBN5	1211	Q9NRC6
TRGCVSEQRLKVFSG	BTG2	26	P78543
ETSRSTQKAIAFCLG	ADGRF5	1121	Q8IZF2
TAKEIALGRCFDGTS	CILP	1086	O75339
LAKEIAIGRCFDGSS	CILP2	1071	Q8IUL8
TLGIFGAATNKVVCS	CHST2	246	Q9Y4C5
KIEATRCSAGISGRN	CLCA4	181	Q14CN2
SLALASGTGLFKCGI	FAP	631	Q12884
ALRNGVRGCFSTKTS	TECTA	1471	O75443
FCKEEFGLTSLGNTS	XIRP2	3196	A4UGR9
SSNGCKTVASRIAFF	TOR2A	306	Q5JU69
LRVAFQEVNSGCTGK	RIN2	791	Q8WYP3
CSVFGLLLTQKGNAT	TNFRSF11B	166	O00300
VSELRCKGSGASSVF	WDR90	1371	Q96KV7
FEGCGRSFTTSNIRK	ZNF143	331	P52747
ICALSITSRGSFEQK	VSNL1	86	P62760
VQLTKTGSVCDFGFA	TIAM2	891	Q8IVF5
QKALSLVSCFAGGVF	SLC39A1	66	Q9NY26
SCISDGISFRGGQKA	SH3PXD2A	461	Q5TCZ1
GNGCRKTFSRSTKQI	ZNF274	481	Q96GC6
GECGKSFRQSSSLFR	ZNF551	366	Q7Z340
TFRVSCRCSGTIGKA	THUMPD2	206	Q9BTF0
CRCSGTIGKAFTAQE	THUMPD2	211	Q9BTF0
FDQESCIRSLEGSGK	TROAP	396	Q12815
LDISGSTFVGFKNVC	PKHD1L1	3606	Q86WI1
GTVYTCSSDGKVRQL	GTF3C4	436	Q9UKN8
DGRQFFSSVSCATKG	PLEKHH1	1346	Q9ULM0
SGKSNILDSICFLLG	SMC2	36	O95347
RSVIFELDSCNGSGK	TPGS2	141	Q68CL5
SECGRGFSQKSNLII	ZNF133	301	P52736
IGNECGKAFRVSSSL	ZNF841	146	Q6ZN19
CGDCGKRFSVSSNLL	ZNF853	571	P0CG23
GECGKAFSRSSTLIQ	ZNF251	296	Q9BRH9
GQCGKSFSQRATLIK	ZNF416	301	Q9BWM5
KIFGFQAGLTSLDCS	VPS13B	736	Q7Z7G8
GDCGKFFSRSSNLIQ	ZNF792	341	Q3KQV3
KACGRGFTQSASLLQ	ZNF843	36	Q8N446
GECGKAFRQSSSLTL	ZNF74	251	Q16587
KECGKAFTRGSQLTQ	ZNF420	646	Q8TAQ5
ASFRNTGEIKALAGC	TALDO1	236	P37837
NECGKAFSFGSALTR	ZNF345	261	Q14585
RLDSAGTVGRLCNKS	WNT10A	351	Q9GZT5
SRTTCFQGVKVDSLG	ZFAND4	521	Q86XD8
ARGCTATLGNFAKAT	RPS2	226	P15880
IGDLFVGQLKSSLTC	USP2	411	O75604
SERLSITKSACGRNG	FLT1	71	P17948
QGFAAVLAIGSSRCK	UBR4	1196	Q5T4S7
TARGFCQIQVKTFGT	TG	1326	P01266
NGRIILSKTFCGSAA	TSSK2	166	Q96PF2
SLGQKCLSFSRAETV	PRSS16	341	Q9NQE7
VLERTCAGSFSGVRK	TBCEL	116	Q5QJ74
VALGCASRGRTIAFA	TKTL1	346	P51854
VFLGGCTFSEISALR	VPS33B	571	Q9H267
LVCGKGFSDRSNFST	ZNF500	356	O60304
NDCGKAFSDGSILIR	ZNF34	366	Q8IZ26
LREKRFCTGSVGEAS	ZNF337	736	Q9Y3M9
SSCSKDVVRTGFDGL	TRAIP	406	Q9BWF2
TDLFGCRKTAVVGAA	SLC16A10	136	Q8TF71
TLGKLNAAISFLCGV	KCNF1	381	Q9H3M0
AGLNTGTAIQCVRFK	MLC1	316	Q15049