Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	FHA_dom	RASIP1 RADIL TCF19 KIF1C	2.76e-05	36	91	4	IPR000253
Domain	-	RASIP1 RADIL TCF19 KIF1C	2.76e-05	36	91	4	2.60.200.20
Domain	GYF	GIGYF2 GIGYF1	7.02e-05	3	91	2	SM00444
Domain	GYF	GIGYF2 GIGYF1	7.02e-05	3	91	2	PS50829
Domain	GYF	GIGYF2 GIGYF1	7.02e-05	3	91	2	PF02213
Domain	-	GIGYF2 GIGYF1	7.02e-05	3	91	2	3.30.1490.40
Domain	SMAD_FHA_domain	RASIP1 RADIL TCF19 KIF1C	1.19e-04	52	91	4	IPR008984
Domain	GYF	GIGYF2 GIGYF1	1.40e-04	4	91	2	IPR003169
Domain	DIL	RASIP1 RADIL	3.48e-04	6	91	2	PF01843
Domain	Dilute_dom	RASIP1 RADIL	3.48e-04	6	91	2	IPR002710
Domain	DILUTE	RASIP1 RADIL	3.48e-04	6	91	2	PS51126
Domain	DIL	RASIP1 RADIL	3.48e-04	6	91	2	SM01132
Domain	FHA_DOMAIN	RADIL TCF19 KIF1C	4.56e-04	31	91	3	PS50006
Domain	SH3_9	ABI3 MAP3K10 RUSC1 ARHGAP33	5.71e-04	78	91	4	PF14604
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCL RADIL PCNX3 KIF26A ANXA11 EMID1 FBRS PEX6 HES6 IRS2 MARVELD3 SYVN1 FHIP1B ZBED3 MYRF CIC IFNLR1 ARHGAP33	8.76e-10	1105	94	18	35748872
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ZNF469 SYNPO2 SPATA31E1 AEBP1 RBBP6 UBQLN3 MRPL43 EPN1 CIC	2.61e-06	430	94	9	35044719
Pubmed	Mutations in CIC and FUBP1 contribute to human oligodendroglioma.	FUBP1 CIC	7.23e-06	2	94	2	21817013
Pubmed	Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors.	FUBP1 CIC	7.23e-06	2	94	2	24030748
Pubmed	CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.	FUBP1 CIC	7.23e-06	2	94	2	22588899
Pubmed	USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.	SYVN1 USP19	7.23e-06	2	94	2	27827840
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RADIL CASKIN2 MINK1 MAP3K10 GIGYF2 IRS2 TMEM102 GIGYF1 CIC RGS12 KIF1C	2.14e-05	861	94	11	36931259
Pubmed	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.	BACH2 SENP3	2.16e-05	3	94	2	30089837
Pubmed	Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.	TNRC6B GIGYF2 SF3B2	3.26e-05	23	94	3	20696395
Pubmed	A census of human transcription factors: function, expression and evolution.	MYCL BACH2 TPRX1 DMRTC2 NR1H2 TEAD4 RAX2 ZBED3 MYRF CIC NPAS1	3.47e-05	908	94	11	19274049
Pubmed	4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay.	GIGYF2 GIGYF1	4.32e-05	4	94	2	33053355
Pubmed	Coronin 2A mediates actin-dependent de-repression of inflammatory response genes.	SENP3 NR1H2	4.32e-05	4	94	2	21331046
Pubmed	Immediate-early response 5 (IER5) interacts with protein phosphatase 2A and regulates the phosphorylation of ribosomal protein S6 kinase and heat shock factor 1.	MINK1 IER5	4.32e-05	4	94	2	26496226
Pubmed	Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.	FUBP1 CIC	4.32e-05	4	94	2	22869205
Pubmed	Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.	IRS2 EPN1	4.32e-05	4	94	2	25879670
Pubmed	Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.	FUBP1 CIC	7.19e-05	5	94	2	26545048
Pubmed	The adapter protein GRB10 is an endogenous negative regulator of insulin-like growth factor signaling.	GIGYF2 GIGYF1	7.19e-05	5	94	2	16037382
Pubmed	Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.	GIGYF2 GIGYF1	7.19e-05	5	94	2	12771153
Pubmed	Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.	GIGYF2 GIGYF1	1.08e-04	6	94	2	20878056
Pubmed	GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.	GIGYF2 GIGYF1	1.08e-04	6	94	2	28698298
Pubmed	Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.	RASIP1 RADIL	1.08e-04	6	94	2	26780829
Pubmed	GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling.	GIGYF2 GIGYF1	1.08e-04	6	94	2	19744960
Pubmed	Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium.	TICAM1 IFNLR1	1.08e-04	6	94	2	35137688
Pubmed	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.	ZMAT5 PDCD7 SF3B2	1.08e-04	34	94	3	15146077
Pubmed	HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.	MINK1 IER5	1.50e-04	7	94	2	25816751
Pubmed	GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling.	GIGYF2 GIGYF1	1.50e-04	7	94	2	30917308
Pubmed	A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.	GIGYF2 GIGYF1	1.50e-04	7	94	2	22751931
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	RBBP6 RGS12	1.50e-04	7	94	2	36700049
Pubmed	Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation.	TICAM1 NR1H2	1.50e-04	7	94	2	32343675
Pubmed	Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation.	TICAM1 NR1H2	2.00e-04	8	94	2	18981140
Pubmed	Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.	TICAM1 IFNLR1	2.00e-04	8	94	2	24278020
Pubmed	Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination.	TICAM1 USP19	2.00e-04	8	94	2	31511519
Pubmed	Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation.	SYVN1 USP19	2.00e-04	8	94	2	24356957
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	BCL9L RADIL TNRC6B GIGYF2 IRS2 GIGYF1 KIF1C	2.13e-04	446	94	7	24255178
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF469 RBBP6 BACH2 FBRS LPCAT4 PEX6 TNRC6B C16orf96 IRS2 GIGYF1 ARHGAP33	2.15e-04	1116	94	11	31753913
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	BCL9L FUBP1 FBRS TNRC6B GIGYF1 TEAD4 CIC	2.47e-04	457	94	7	32344865
Pubmed	Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.	GIGYF2 GIGYF1	2.57e-04	9	94	2	31439631
Pubmed	Identification of novel Smad binding proteins.	PEX6 SF3B2	2.57e-04	9	94	2	14651998
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	FNDC10 AEBP1 GIGYF2 RGS12	2.84e-04	116	94	4	30652415
Pubmed	A human MAP kinase interactome.	SYNPO2 KIF26A RBBP6 MAP3K10 GIGYF2 CIC ARHGAP33	3.58e-04	486	94	7	20936779
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CASKIN2 SENP3 MINK1 PEX6 GIGYF2 GIGYF1 EPN1 SF3B2	3.87e-04	650	94	8	38777146
Pubmed	ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.	PCNX3 EPN1	3.91e-04	11	94	2	34927784
Pubmed	Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.	TCF19 PSORS1C2	4.69e-04	12	94	2	23955597
Pubmed	Accelerated failure time models provide a useful statistical framework for aging research.	PAPPA IRS2	4.69e-04	12	94	2	19007875
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	FBRS TNRC6B MCRIP2 CIC	7.88e-04	152	94	4	38360978
Pubmed	CHIP as a membrane-shuttling proteostasis sensor.	TNRC6B GIGYF1 ARHGAP33	8.44e-04	68	94	3	29091030
Pubmed	Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.	FUBP1 TNRC6B	8.46e-04	16	94	2	32414810
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNRC6B GIGYF2 SYVN1 FHIP1B MARCHF4 USP19	8.47e-04	407	94	6	12693553
Pubmed	Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.	KCNC3 ATXN8OS	9.57e-04	17	94	2	15148151
Pubmed	Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome.	RBBP6 ARHGAP33	9.57e-04	17	94	2	20873783
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FBRS RUSC1 TNRC6B GIGYF2 IRS2 CIC	9.72e-04	418	94	6	34709266
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	TNRC6B GIGYF2	1.08e-03	18	94	2	25363768
Pubmed	Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.	TICAM1 BACH2	1.20e-03	19	94	2	22561518
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBBP6 FUBP1 MINK1 GIGYF2 IRS2 SF3B2 CIC USP19	1.20e-03	774	94	8	15302935
Pubmed	Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.	BCL9L RASIP1 FUBP1 IRS2	1.30e-03	174	94	4	29669786
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	RBBP6 TNRC6B GIGYF2 GIGYF1	1.60e-03	184	94	4	32908313
Pubmed	Identification of genes related to Parkinson's disease using expressed sequence tags.	ZMAT5 HES6 MCRIP2	1.61e-03	85	94	3	17213182
Pubmed	Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.	ABI3 MAPK1IP1L MINK1 SF3B2	1.66e-03	186	94	4	31540324
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SENP3 FBRS IRS2 PDCD7 SEC31B ZBED3 CIC	1.75e-03	638	94	7	31182584
Pubmed	Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.	NRIP2 XIRP1	1.76e-03	23	94	2	23117660
Pubmed	The sequence and analysis of duplication-rich human chromosome 16.	C16orf96 MARVELD3 MCRIP2	1.89e-03	90	94	3	15616553
Pubmed	Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.	BACH2 IL2RB	2.08e-03	25	94	2	21829393
Pubmed	Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.	MYCL HES6 NPAS1	2.42e-03	98	94	3	18557763
Pubmed	Parkinson Disease Overview	ATXN8OS GIGYF2	2.43e-03	27	94	2	20301402
Pubmed	Retinoic Acid Antagonizes Testis Development in Mice.	ADAMTS19 INHBB	2.43e-03	27	94	2	30067986
Pubmed	Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.	ANXA11 PSORS1C2	2.43e-03	27	94	2	23144326
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	RBBP6 SYVN1	2.61e-03	28	94	2	35474067
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	MYCL TCF19 AEBP1 DMRTC2 HES6 NR1H2 TEAD4 CIC	2.62e-03	877	94	8	20211142
Interaction	TOP3B interactions	MYCL RADIL PCNX3 RTEL1 KIF26A ANXA11 EMID1 FBRS PEX6 TNRC6B HES6 IRS2 MARVELD3 SYVN1 FHIP1B ZBED3 MYRF MCRIP2 CIC IFNLR1 ARHGAP33	2.62e-06	1470	93	21	int:TOP3B
Interaction	VASP interactions	XIRP1 ABI3 AEBP1 PSORS1C2 MRPL43 TNRC6B IRS2 TEAD4 SF3B2	8.72e-06	294	93	9	int:VASP
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	IL11 RASIP1 KCNC3 GGN MAP3K10 TPRX1 DMRTC2 NR1H2 EPN1 CIC ARHGAP33 NPAS1	6.70e-06	1192	95	12	chr19q13
Cytoband	19q13.2	GGN MAP3K10 DMRTC2 CIC	3.88e-04	164	95	4	19q13.2
Cytoband	10q24.31	MRPL43 SEC31B	7.08e-04	19	95	2	10q24.31
Cytoband	19q13.33	RASIP1 KCNC3 TPRX1	1.42e-03	106	95	3	19q13.33
Cytoband	Ensembl 112 genes in cytogenetic band chr22q12	ZMAT5 EMID1 IL2RB INPP5J	1.48e-03	235	95	4	chr22q12
Coexpression	GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_UP	ZDHHC18 RBBP6 IER5	6.99e-06	11	93	3	M19724
Coexpression	GSE14026_TH1_VS_TH17_UP	IL11 SENP3 FBRS C16orf96 PDCD7 MARCHF4 MCRIP2	7.38e-06	200	93	7	M3356
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	RBBP6 TICAM1 MINK1 GIGYF1 TEAD4 SEC31B EPN1 CIC	2.77e-05	338	93	8	M17094
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP2 RASIP1 XIRP1 SYNPO2 ABI3 INHBB	3.53e-06	194	94	6	9d7cbbcf995274019ca10be0562f114513ec197a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALR1 TMEM132E EMID1 RGS12 NPAS1	5.87e-06	121	94	5	7f2057367777c6c92f596054cbc5fe567d079fbc
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF19 DMRTC2 PDCD7 IL2RB ARHGAP33	2.20e-05	159	94	5	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3 MINK1 FHIP1B MFSD13A INPP5J	2.87e-05	168	94	5	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TCERG1L PRR36 INHBB HES6 MARCHF4	3.04e-05	170	94	5	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL IL11 TCF19 BACH2 LPCAT4	3.49e-05	175	94	5	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RTEL1 BACH2 MAP3K10 GIGYF1 SYVN1	3.49e-05	175	94	5	f86d2d212f8314b2410d5d84ef092b0b38607ea4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 CARMIL3 EMID1 RGS12 NPAS1	3.99e-05	180	94	5	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	RASIP1 SYNPO2 CASKIN2 EMID1 TEAD4	4.20e-05	182	94	5	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 P3H2	4.32e-05	183	94	5	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 P3H2	4.32e-05	183	94	5	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	droplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 SYNPO2 EMID1 CACNA1G	4.43e-05	184	94	5	f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 CACNA1G	4.54e-05	185	94	5	30df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 CACNA1G	4.78e-05	187	94	5	8ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GALR1 TCERG1L INHBB HES6 MARCHF4	5.16e-05	190	94	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	Influenza_Severe-Non-classical_Monocyte\|Influenza_Severe / Disease group and Cell class	ABI3 FNDC10 IER5 MCRIP2 RGS12	5.29e-05	191	94	5	197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALR1 TCERG1L INHBB HES6 MARCHF4	5.56e-05	193	94	5	8603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132E BACH2 SCN4A IRS2 SYVN1	5.69e-05	194	94	5	11709704079f24a730476572dc2f01e9d2226e2c
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132E BACH2 SCN4A IRS2 SYVN1	5.69e-05	194	94	5	3a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALR1 TCERG1L KCNC3 KIF26A HES6	5.69e-05	194	94	5	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 EMID1	5.69e-05	194	94	5	b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCell	droplet-Bladder-Unstain-18m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 XIRP1 SYNPO2 ABI3 INHBB	5.83e-05	195	94	5	fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 XIRP1 SYNPO2 ABI3 INHBB	5.83e-05	195	94	5	2a6056172c41c46acfe0242be22269ef1d07921e
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALR1 TCERG1L INHBB HES6 MARCHF4	5.83e-05	195	94	5	5f33ece997f074598b4201ff74f592ee07c86a06
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 NRIP2 XIRP1 SYNPO2 EMID1	5.83e-05	195	94	5	0bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	AEBP1 KIF26A TMEM132E EMID1 PAPPA	6.58e-05	200	94	5	16a3685c41194a0a4a772e4eee372160263480e0
Drug	Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ZMAT5 CASKIN2 ANXA11 MINK1 LPCAT4 TEAD4 INPP5J USP19	1.32e-06	194	93	8	2792_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	MYCL RTEL1 CASKIN2 MINK1 FBRS IRS2 RGS12 KIF1C	1.48e-06	197	93	8	5211_DN
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	MYCL RTEL1 CASKIN2 LPCAT4 TNRC6B RGS12 KIF1C	1.60e-05	196	93	7	5350_UP
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	MYCL IL11 PEX6 PAPPA EPN1 IL2RB KIF1C	1.65e-05	197	93	7	3350_UP
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MYCL PRR36 MINK1 EMID1 IRS2 USP19 ARHGAP33	1.70e-05	198	93	7	3843_DN
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	RASIP1 PRR36 IL2RB CIC RGS12 INPP5J ARHGAP33	1.70e-05	198	93	7	5213_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MYCL PRR36 RTEL1 TICAM1 EMID1 RGS12 USP19	1.76e-05	199	93	7	3203_DN
Disease	syntaxin-1a measurement	HGFAC RGS12	8.94e-05	5	89	2	EFO_0020759
Disease	hepatocyte growth factor activator measurement	HGFAC RGS12	1.87e-04	7	89	2	EFO_0008152
Disease	1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement	PEX6 MYRF	2.49e-04	8	89	2	EFO_0800392
Disease	Crohn's disease	RASIP1 HGFAC TCERG1L BACH2 C16orf96 SYVN1 MYRF	3.82e-04	441	89	7	EFO_0000384
Disease	Nasal Cavity Polyp	BACH2 GIGYF2 MYRF	6.21e-04	55	89	3	EFO_1000391
Disease	apolipoprotein B measurement	SORT1 HGFAC PSORS1C2 PEX6 GIGYF1 MARVELD3 MYRF RGS12	8.90e-04	663	89	8	EFO_0004615
Disease	psoriasis	DDR1 TCF19 P3H2 PSORS1C2 IFNLR1	1.44e-03	273	89	5	EFO_0000676
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	HGFAC SEC31B MYRF	1.71e-03	78	89	3	EFO_0022187
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	SYNPO2 TPRX1	2.00e-03	22	89	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	Parkinson disease	ATXN8OS GIGYF2	2.00e-03	22	89	2	cv:C0030567
Disease	triacylglycerol 58:9 measurement	TMEM132E MYRF	2.00e-03	22	89	2	EFO_0010443
Disease	Glioma	RTEL1 FUBP1 CIC	2.34e-03	87	89	3	C0017638
Disease	eye measurement	RASIP1 ZNF469	3.01e-03	27	89	2	EFO_0004731
Disease	gamma-glutamyltyrosine measurement	MARVELD3 SLC16A10	3.01e-03	27	89	2	EFO_0021144

Protein segments in the cluster

Peptide	Gene	Start	Entry
GRSAPLAPWSPPPGP	FAM246C	181	P0DSO1
EPGAAPPGPPWAPSN	BACH2	771	Q9BYV9
GPWGGAAYPPPPSMP	ANXA11	21	P50995
SETLEWPLPPPPSPG	AEBP1	176	Q8IUX7
LGGTFPPAPWWPPGP	DDR1	376	Q08345
GPGRGPPAAWDPPPA	RASIP1	876	Q5U651
LPLEPWLGPGPPAVP	RAX2	116	Q96IS3
ALSPGAPASWQPPPP	ADAMTS19	131	Q8TE59
WPAGGAPGSPIPSPP	HES6	161	Q96HZ4
DPVRPWGLAPPGDPP	NPAS1	506	Q99742
PSTPLGPEPGDPDWP	RADIL	906	Q96JH8
PPPPPGFGPDEPSWV	ABI3	291	Q9P2A4
PPPQLNGVPGSWPEG	FHIP1B	631	Q8N612
PGARAPWEPTPSAPP	MAP3K10	646	Q02779
PPDGPGAPAAEPWPG	MAP10	71	Q9P2G4
PPAPSSPPPLWAGLA	GIGYF1	751	O75420
PGDWAPLDPTPGPPA	LPCAT4	6	Q643R3
WGTLPPEPNLVPGGP	IFNLR1	451	Q8IU57
PAPHGPPAPYAPQGW	FUBP1	496	Q96AE4
QPPPAGPPVEGDGWL	ATXN8OS	76	P0DMR3
AWGSPTPPPTPAAPP	INHBB	26	P09529
DAGPGSWKPPPPPQS	CARMIL3	1196	Q8ND23
PPAPPLAPPSSAWGG	IL11	156	P20809
SGDGRPPPLLQWPPP	PCNX3	1886	Q9H6A9
PPGPGPPWSPRWPEA	PDCD7	111	Q8N8D1
TPPLAVLLPPGGPWP	PEX6	16	Q13608
VPPPPGPPSEPVDWN	KIF1C	611	O43896
PWESPHAPAPPAAPG	LRRC37B	56	Q96QE4
PDSPGPTWGPCPGEV	KIF26A	1166	Q9ULI4
PSHKGTPPTPNPWGP	PRR25	126	Q96S07
AALSGPWGSPPPPPE	GGN	381	Q86UU5
LLLPPPLWGGPPDSP	P3H2	16	Q8IVL5
RASPPPPPPPGGAWE	PAPPA	56	Q13219
PPPPPGGAWEAVRVP	PAPPA	61	Q13219
WVPSPWPPPGLGPFL	HGFAC	6	Q04756
PAPGPPPGAPWAFSY	CASKIN2	766	Q8WXE0
PPGFPPAPANLSTPW	RBBP6	601	Q7Z6E9
PPPPLPQPGDKSSWG	IRS2	1271	Q9Y4H2
GEGAGPPPPYPTPSW	ARHGAP33	1261	O14559
GNASWPEPPAPEPGP	GALR1	11	P47211
PGAPPAFASPPDPWG	FBRS	211	Q9HAH7
MWGRVPFSPGPAPPP	GIGYF2	586	Q6Y7W6
MTPPAPCPGPEPNWG	CACNA1G	2191	O43497
PCPGPEPNWGKGPPE	CACNA1G	2196	O43497
VPPGPWVPGHWLPPG	DMRTC2	171	Q8IXT2
PWPVLGPVPAPGAQP	C16orf96	366	A6NNT2
PGAQPPPLGDWPALP	C16orf96	376	A6NNT2
AAPTPPGWEPTPDAP	FNDC10	21	F2Z333
DWDPQPLGPPTPGVP	IL2RB	466	P14784
PPPYHSKPGDQWPPG	BCL9L	561	Q86UU0
AQPPGPWPLSSPGPR	MCRIP2	51	Q9BUT9
AAAPPGPAPWEAPEP	MARVELD3	126	Q96A59
PPPPLPPSSVEDDWG	MARCHF4	106	Q9P2E8
PTSDPWGGPPVPPAA	EPN1	291	Q9Y6I3
VPPAADPWGGPAPTP	EPN1	301	Q9Y6I3
PTPATPEDPAPLWGP	EMID1	166	Q96A84
PEDPAPLWGPPPAQG	EMID1	171	Q96A84
GAKGDPEPWPGPEPP	FIGNL2	91	A6NMB9
TPVGSAHPWPEPPAP	MFSD13A	441	Q14CX5
PGAWGPPAPYPAPTG	MAPK1IP1L	196	Q8NDC0
EGPGPSPNPPAWVRP	MINK1	646	Q8N4C8
TPPPSSPWPTPPAGA	NRIP2	36	Q9BQI9
AAGPPAGWGEPPPPA	IER5	76	Q5VY09
PAPPVPPRDPPVGWA	RUSC1	381	Q9BVN2
PRPPPTGDPGSQPQW	RTEL1	1031	Q9NZ71
PEAGPAPGFPFPPPW	SYVN1	446	Q86TM6
PGWPDPPDLPTVDPI	MRPL43	171	Q8N983
PPPAAPLPRWSGPIG	SORT1	41	Q99523
AWPPAPPPGQTVRPG	SCN4A	1816	P35499
PLAWFGPPAPAAPPT	TMEM132E	196	Q6IEE7
PGAPLPWPPATGPGS	PRR36	1176	Q9H6K5
EPWPGGPDPDVPGTD	NR1H2	36	P55055
SWAPPPREPVSPAGP	SPATA31E1	1401	Q6ZUB1
PVGFPGTWPLPGSPL	SEC31B	901	Q9NQW1
PPPPESGPGQPGWEG	CIC	1576	Q96RK0
WGGPKSLPVPAPPGE	TCF19	196	Q9Y242
PPPPGPAAAPEGDWA	ZBED3	116	Q96IU2
PSGLPGPWAFPPAVP	INPP5J	941	Q15735
APPPAAPLLPGLPGW	TCERG1L	66	Q5VWI1
WGPEPPGPGIPPAYS	SENP3	11	Q9H4L4
PPPPPPGHYGAWAAQ	SF3B2	16	Q13435
EPVPEGSGPLGPWGP	USP19	1256	O94966
IPGPGSLPAPAPLWP	TPRX1	321	Q8N7U7
PWTGPFCPDPEGSPP	RGS12	471	O14924
AGPAQPPPWPQPAPW	SYNPO2	641	Q9UMS6
VPSPPTSPPWGLGPG	MYCL	36	P12524
AGDPAPGIGPPEPWP	MYCL	51	P12524
GQVPLGAPPPFPTWP	TICAM1	611	Q8IUC6
WWGPPPPAPARPLTD	TMEM102	11	Q8N9M5
GPQPSAPFPDPPGWR	TMEM79	81	Q9BSE2
GPAPSPSAPPAPPWQ	TEAD4	201	Q15561
WDPTAAPYPTPPGGP	ZNF469	441	Q96JG9
PVPWPPVGPSPGQGE	FP248	171	Q71RG6
PSLRAPPPGGWPLQP	ZMAT5	151	Q9UDW3
PEPAPPSASPLPRGW	XIRP1	1731	Q702N8
AAIPGIPEPPWLPSP	UBQLN3	466	Q9H347
GPAPPAAPAPPRWSS	ZDHHC18	36	Q9NUE0
PPQPEASGSWGGPPP	TNRC6B	831	Q9UPQ9
GDPWPGAPPLFEDPP	PSORS1C2	51	Q9UIG4
WPAGPQPPENPWPPA	PSORS1C2	101	Q9UIG4
GAPPLPPQDWRKPGP	KCNC3	726	Q14003
AEPHEPPEPPEGGWG	SLC16A10	56	Q8TF71
PWPPQGPLSPGPGSL	MYRF	296	Q9Y2G1