Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	VIL1 NRAP NEBL SPTBN1 NEB IQGAP1 BLOC1S6 XIRP2 IQGAP3 FMNL1	3.14e-05	227	174	10	GO:0051015
GeneOntologyMolecularFunction	N-succinyltransferase activity	ALAS1 ALAS2	7.55e-05	2	174	2	GO:0016749
GeneOntologyMolecularFunction	5-aminolevulinate synthase activity	ALAS1 ALAS2	7.55e-05	2	174	2	GO:0003870
GeneOntologyMolecularFunction	succinyltransferase activity	ALAS1 ALAS2	2.25e-04	3	174	2	GO:0016748
GeneOntologyMolecularFunction	RNA polymerase binding	ERCC6 CCNT1 SCAF1 TCERG1 RECQL5	2.57e-04	65	174	5	GO:0070063
GeneOntologyBiologicalProcess	cardiac muscle thin filament assembly	NRAP NEBL NEB	5.70e-07	3	172	3	GO:0071691
GeneOntologyBiologicalProcess	organelle assembly	ATG5 VIL1 PLK2 NRAP NEBL STAG1 SMC1A TTLL5 ATG14 OCRL RB1CC1 NEB TBC1D32 MRPS7 ODF2L BLOC1S6 ALMS1 CEP44 TTC21B CEP70 ASPM STYXL1 ATM CFAP70 SPAG16 VPS13B	2.80e-06	1138	172	26	GO:0070925
GeneOntologyBiologicalProcess	phosphatidylinositol-3-phosphate biosynthetic process	ATG14 OCRL PIK3C2G ATM	3.04e-05	22	172	4	GO:0036092
GeneOntologyBiologicalProcess	actin cytoskeleton organization	VIL1 NRAP CDC42BPA NEBL PDGFA POTEF PCLO SPTBN1 NEB IQGAP1 POTEE BLOC1S6 FAT1 ALMS1 BAIAP2L1 XIRP2 PDCD10 IQGAP3 FMNL1	4.31e-05	803	172	19	GO:0030036
GeneOntologyBiologicalProcess	actin filament-based process	VIL1 NRAP CDC42BPA NEBL PDGFA POTEF PCLO SPTBN1 NEB IQGAP1 POTEE BLOC1S6 FAT1 ALMS1 BAIAP2L1 FRMD6 XIRP2 PDCD10 IQGAP3 FMNL1	7.70e-05	912	172	20	GO:0030029
GeneOntologyCellularComponent	spindle pole	PLK2 STAG1 SMC1A IKBKG FAM110A ALMS1 CEP95 CEP44 ASPM	6.80e-05	205	178	9	GO:0000922
Domain	Nebulin	NRAP NEBL NEB	3.05e-06	4	172	3	PF00880
Domain	NEBULIN	NRAP NEBL NEB	3.05e-06	4	172	3	PS51216
Domain	NEBU	NRAP NEBL NEB	3.05e-06	4	172	3	SM00227
Domain	Nebulin	NRAP NEBL NEB	3.05e-06	4	172	3	IPR013998
Domain	Nebulin_repeat	NRAP NEBL NEB	3.05e-06	4	172	3	IPR000900
Domain	-	SPTBN1 IQGAP1 CEP95 ASPM VAV3 IQGAP3	4.88e-05	71	172	6	1.10.418.10
Domain	CH-domain	SPTBN1 IQGAP1 CEP95 ASPM VAV3 IQGAP3	6.65e-05	75	172	6	IPR001715
Domain	Preseq_ALAS	ALAS1 ALAS2	8.43e-05	2	172	2	PF09029
Domain	4pyrrol_synth_NH2levulA_synth	ALAS1 ALAS2	8.43e-05	2	172	2	IPR010961
Domain	5aminolev_synth_preseq	ALAS1 ALAS2	8.43e-05	2	172	2	IPR015118
Domain	RasGAP_C	IQGAP1 IQGAP3	2.51e-04	3	172	2	IPR000593
Domain	RasGAP_C	IQGAP1 IQGAP3	2.51e-04	3	172	2	PF03836
Domain	CH	SPTBN1 IQGAP1 ASPM VAV3 IQGAP3	3.30e-04	65	172	5	SM00033
Domain	CH	SPTBN1 IQGAP1 ASPM VAV3 IQGAP3	4.66e-04	70	172	5	PF00307
Domain	PPR	DENND4A DENND4C	5.00e-04	4	172	2	PF01535
Domain	CH	SPTBN1 IQGAP1 ASPM VAV3 IQGAP3	5.66e-04	73	172	5	PS50021
Pathway	WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR	SMC1A IKBKG PALB2 RFWD3 RECQL5 ATM TDP1	8.59e-06	81	128	7	M39490
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	VIL1 DENND4A PDGFA STAG1 POTEF PSMA2 PCLO UGGT1 SPTBN1 NMRAL1 APOB GPR101 NEB TRIP12 PALB2 TASOR2 IQGAP1 ZNF675 POTEE SNRNP48 ASPM MRPS9 KMT2A PADI6 GNAI2 ALAS2 ATM RAB3B	1.55e-09	1442	179	28	35575683
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATG5 PLK2 STAG1 SMC1A TTLL5 SPTBN1 DEF8 ZNF521 CRTAC1 ARMCX4 APP TRIP12 LRP1B IQGAP1 ODF2L SNRNP48 TIAM1 TCERG1 SLF2 ZNF451 CEP70 MRPS9 ANKRD36 ATM CABIN1 USP33	2.73e-09	1285	179	26	35914814
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CDC42BPA POTEF TPTE2 UGGT1 RFWD3 IQGAP1 AGL RRP12 ZNF638 KMT2A IQGAP3	9.14e-09	202	179	11	24639526
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	PRPF31 ERCC6 GATAD2A RNPC3 SMC1A ATG14 TACC2 TRIP12 IQGAP1 MRPS7 ACAD11 TCERG1 UBTF RRP12 SCAPER ASPM IQGAP3 MED12 HERC5	1.64e-08	759	179	19	35915203
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	PRPF31 ERCC6 ARHGAP23 ABCA12 POTEF PSMA2 SH2D3C APOB NEB PALB2 NEK4 POTEE TTC21B IGSF1 LRRC37B	7.90e-08	513	179	15	25798074
Pubmed	Human transcription factor protein interaction networks.	NOL4 SLF1 CDC42BPA GATAD2A CNOT10 PSMA2 SMC1A SPTBN1 ZNF521 IKBKG IRAK1 MRPS7 FAT1 ALMS1 TCERG1 CTCF UBTF ZNF451 RRP12 RECQL5 ZNF638 MRPS9 KMT2A CABIN1 FILIP1L	9.57e-08	1429	179	25	35140242
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRPF31 PLK2 DENND4A CDC42BPA POTEF SPTBN1 RALGAPB RALGPS2 TRIP12 DENND4C NEK4 ALMS1 TIAM1 BAIAP2L1 TCERG1 FRMD6 SLF2 CEP95 KMT2A	1.18e-07	861	179	19	36931259
Pubmed	Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine.	ATG5 RB1CC1 KMT2A	1.34e-07	3	179	3	28282266
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ATG5 PRPF31 DIS3L2 ERCC6 GATAD2A ARHGAP23 PSMA2 SMC1A SPTBN1 OCRL TRIP12 IQGAP1 CCNT1 MRPS7 TCERG1 UBTF RRP12 RECQL5 ASPM ZNF638 GNAI2 PRR14L MED12 ALDH7A1	1.38e-07	1353	179	24	29467282
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PRPF31 PLK2 STAG1 CNOT10 SMC1A PACSIN3 TACC2 FAM110A FBXO30 TASOR2 IQGAP1 MRPS7 ODF2L CTCF ZNF451 RRP12 ASPM GNAI2 ATM PDCD10 IQGAP3 VPS13B	1.44e-07	1155	179	22	20360068
Pubmed	Atg14 protects the intestinal epithelium from TNF-triggered villus atrophy.	ATG5 ATG14 RB1CC1	5.34e-07	4	179	3	30894050
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB XIRP2	5.34e-07	4	179	3	23985323
Pubmed	Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.	STAG1 SMC1A CTCF	1.33e-06	5	179	3	18219272
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CNOT10 PSMA2 TTLL5 FAM91A1 TRIP12 PALB2 DENND4C ODF2L ALMS1 TBK1 RECQL5 ZNF638 KMT2A CABIN1 MED12	1.42e-06	645	179	15	25281560
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PRPF31 STAG1 SMC1A SPTBN1 TRIP12 IQGAP1 VPS52 CEP70 GNAI2 MED12	1.64e-06	272	179	10	31010829
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PRPF31 ERCC6 SPTBN1 ETF1 NEB TRIP12 IFIH1 XIRP2 UBTF RRP12 KMT2A ATM MED12	2.05e-06	497	179	13	36774506
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	ERCC6 CNOT10 ETF1 BAIAP2L1 SCAPER ZNF638 MRPS9 KMT2A CABIN1 MED12	2.19e-06	281	179	10	24163370
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PRPF31 ERCC6 GATAD2A SMC1A UGGT1 SPTBN1 ETF1 PACSIN3 TRIP12 TASOR2 IQGAP1 MRPS7 BAIAP2L1 TCERG1 UBTF RRP12 STON2 ZNF638 MRPS9 GNAI2 IQGAP3	2.30e-06	1257	179	21	36526897
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ERCC6 SMC1A CCNT1 ACAD11 SLF2 UBTF ZNF451 RECQL5 IQGAP3	2.48e-06	222	179	9	37071664
Pubmed	Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.	CCNT1 KMT2A AFF1	2.65e-06	6	179	3	21896721
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRPF31 ERCC6 CDC42BPA NEBL CNOT10 RALGAPB PACSIN3 FAM91A1 FAM110A APP IQGAP1 POTEE CCNT1 MRPS7 SCAF1 ACAD11 TCERG1 CTCF RRP12 RECQL5 KMT2A IQGAP3 MED12	2.97e-06	1497	179	23	31527615
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PRPF31 ZNF567 NOL4 ERCC6 GATAD2A STAG1 SMC1A TRIP12 CCNT1 UBTF ZNF451 RECQL5 KMT2A CABIN1	3.61e-06	608	179	14	36089195
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PRPF31 DENND4A CNOT10 PSMA2 SMC1A RALGPS2 FAM110A OCRL CCDC122 DENND4C FBXO30 IQGAP1 NEK4 TBC1D32 TIAM1 CEP44 TBK1 TTC21B ZNF638 SPAG16 IQGAP3	4.94e-06	1321	179	21	27173435
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PRPF31 CDC42BPA GATAD2A ARHGAP23 IKBKG IRAK1 RB1CC1 CCNT1 ACAD11 TBK1 STON2 SCAPER KMT2A AFF1 VAV3 ANKRD36 PDCD10	5.31e-06	910	179	17	36736316
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NOL4 ERCC6 GATAD2A ARHGAP23 ABCA12 IRAK1 E2F2 APP RNF43 CCNT1 SCAF1 FAT1 VPS52 ALMS1 ACAD11 CTCF TBK1 SCAPER ASPM	5.50e-06	1116	179	19	31753913
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	PRPF31 RNPC3 MRPS7 SCAF1 SNRNP48 CTCF ZNF638 MRPS9 KMT2A	6.72e-06	251	179	9	31076518
Pubmed	Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.	ATG14 RB1CC1 TBK1	7.37e-06	8	179	3	30853401
Pubmed	Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.	ATG5 ATG14 RB1CC1	7.37e-06	8	179	3	23262492
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PRPF31 ERCC6 CDC42BPA GATAD2A SMC1A PACSIN3 TRIP12 CCNT1 TCERG1 CTCF UBTF RRP12 ZNF638 MRPS9 KMT2A GNAI2	8.86e-06	847	179	16	35850772
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DENND4A NRAP CDC42BPA SMC1A SPTBN1 FAM110A NEB ALMS1 XIRP2 AGL TBK1 TRIM55	1.14e-05	497	179	12	23414517
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	E2F2 TACC2 POTEE ODF2L ALMS1 BAIAP2L1 TCERG1 SLF2 CEP44 ZNF451 TBK1 RECQL5 ASPM	1.25e-05	588	179	13	38580884
Pubmed	A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.	CCNT1 KMT2A AFF1	1.57e-05	10	179	3	20153263
Pubmed	Autophagy proteins control goblet cell function by potentiating reactive oxygen species production.	ATG5 ATG14 RB1CC1	1.57e-05	10	179	3	24185898
Pubmed	LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.	ATG5 ATG14 RB1CC1	1.57e-05	10	179	3	31257024
Pubmed	Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.	ATG5 ATG14 RB1CC1	1.57e-05	10	179	3	26764600
Pubmed	p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.	ATG5 ATG14 RB1CC1	1.57e-05	10	179	3	21220506
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	RNF166 ETF1 IKBKG FBXO30 RFWD3 MRPS7 SCAF1 ACAD11 TBK1 STON2 MRPS9 TDP1 IQGAP3	1.66e-05	604	179	13	38803224
Pubmed	Network organization of the human autophagy system.	ATG5 SMC1A IRAK1 ATG14 RB1CC1 IQGAP1 BAIAP2L1 XIRP2 AGL TBK1 ALDH7A1	1.82e-05	437	179	11	20562859
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DENND4A FAM91A1 TACC2 OCRL RB1CC1 VPS52 STON2 AFF1 USP33	1.85e-05	285	179	9	34369648
Pubmed	Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.	ATG5 ATG14 RB1CC1	2.15e-05	11	179	3	26764599
Pubmed	Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation.	FRMD4A TIAM1 SCAPER	2.15e-05	11	179	3	20654717
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DENND4A CNOT10 SMC1A RALGAPB RALGPS2 DENND4C NEK4 ALMS1 ACAD11 TBK1 FMNL1	2.20e-05	446	179	11	24255178
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CDC42BPA GATAD2A ARHGAP23 PSMA2 SMC1A UGGT1 FASTKD1 OCRL POTEE CCNT1 MRPS7 TIAM1 TCERG1 KMT2A VAV3 PDCD10	2.31e-05	916	179	16	32203420
Pubmed	The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression.	KMT2A AFF1	2.63e-05	2	179	2	16169901
Pubmed	Autophagy Regulates Craniofacial Bone Acquisition.	ATG5 RB1CC1	2.63e-05	2	179	2	31372669
Pubmed	Functional analysis of the two reciprocal fusion genes MLL-NEBL and NEBL-MLL reveal their oncogenic potential.	NEBL KMT2A	2.63e-05	2	179	2	23340173
Pubmed	The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress.	ERCC6 CTCF	2.63e-05	2	179	2	26578602
Pubmed	CTCF physically links cohesin to chromatin.	STAG1 CTCF	2.63e-05	2	179	2	18550811
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	2.63e-05	2	179	2	19669888
Pubmed	Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.	KMT2A AFF1	2.63e-05	2	179	2	17889710
Pubmed	CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.	ATG5 RB1CC1	2.63e-05	2	179	2	36735498
Pubmed	Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.	CTCF KMT2A	2.63e-05	2	179	2	34405474
Pubmed	CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.	STAG1 CTCF	2.63e-05	2	179	2	27219007
Pubmed	Analysis of the acrolein-modified sites of apolipoprotein B-100 in LDL.	APOB SCAF1	2.63e-05	2	179	2	32919080
Pubmed	Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.	KMT2A AFF1	2.63e-05	2	179	2	7689231
Pubmed	Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.	KMT2A AFF1	2.63e-05	2	179	2	11930009
Pubmed	Genetic and Epigenetic Characterization of a Discordant KMT2A/AFF1-Rearranged Infant Monozygotic Twin Pair.	KMT2A AFF1	2.63e-05	2	179	2	34575904
Pubmed	MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation.	KMT2A AFF1	2.63e-05	2	179	2	27856324
Pubmed	The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(4;11).	KMT2A AFF1	2.63e-05	2	179	2	34489550
Pubmed	A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy.	KMT2A AFF1	2.63e-05	2	179	2	16551973
Pubmed	The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.	KMT2A AFF1	2.63e-05	2	179	2	1423625
Pubmed	Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease.	ATG5 APOB	2.63e-05	2	179	2	36912305
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	2.63e-05	2	179	2	19851499
Pubmed	Interactome Analysis Reveals a Link of the Novel ALMS1-CEP70 Complex to Centrosomal Clusters.	ALMS1 CEP70	2.63e-05	2	179	2	38122899
Pubmed	Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.	PDGFA APP	2.63e-05	2	179	2	12645527
Pubmed	Amyloid-beta colocalizes with apolipoprotein B in absorptive cells of the small intestine.	APOB APP	2.63e-05	2	179	2	19845970
Pubmed	Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias.	KMT2A AFF1	2.63e-05	2	179	2	9326653
Pubmed	Structure of a mouse erythroid 5-aminolevulinate synthase gene and mapping of erythroid-specific DNAse I hypersensitive sites.	ALAS1 ALAS2	2.63e-05	2	179	2	2780318
Pubmed	Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators.	SMC1A CTCF	2.63e-05	2	179	2	25875106
Pubmed	ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis.	ATG14 RB1CC1	2.63e-05	2	179	2	33794726
Pubmed	Human delta-aminolevulinate synthase: assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome.	ALAS1 ALAS2	2.63e-05	2	179	2	2347585
Pubmed	ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.	ZNF521 KMT2A	2.63e-05	2	179	2	28412727
Pubmed	Two different genes encode delta-aminolevulinate synthase in humans: nucleotide sequences of cDNAs for the housekeeping and erythroid genes.	ALAS1 ALAS2	2.63e-05	2	179	2	2263504
Pubmed	Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.	KMT2A AFF1	2.63e-05	2	179	2	21135858
Pubmed	Amlexanox Downregulates S100A6 to Sensitize KMT2A/AFF1-Positive Acute Lymphoblastic Leukemia to TNFα Treatment.	KMT2A AFF1	2.63e-05	2	179	2	28646023
Pubmed	Establishment of MLL/AF4 transgenic mice with the phenotype of lymphoblastic leukemia or lymphoma.	KMT2A AFF1	2.63e-05	2	179	2	24189350
Pubmed	Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer.	PALB2 ATM	2.63e-05	2	179	2	23561644
Pubmed	H3K79 methylation profiles define murine and human MLL-AF4 leukemias.	KMT2A AFF1	2.63e-05	2	179	2	18977325
Pubmed	Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein.	KMT2A AFF1	2.63e-05	2	179	2	14990976
Pubmed	ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.	IKBKG ATM	2.63e-05	2	179	2	19079347
Pubmed	Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein.	APP GNAI2	2.63e-05	2	179	2	20932279
Pubmed	Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.	KMT2A ATM	2.63e-05	2	179	2	26657054
Pubmed	Genomic studies of multiple myeloma reveal an association between X chromosome alterations and genomic profile complexity.	IKBKG IRAK1	2.63e-05	2	179	2	27454822
Pubmed	The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase.	ALAS1 ALAS2	2.63e-05	2	179	2	11566198
Pubmed	Serine 254 enhances an induced fit mechanism in murine 5-aminolevulinate synthase.	ALAS1 ALAS2	2.63e-05	2	179	2	19917609
Pubmed	The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF- kappaB activation.	IKBKG ATM	2.63e-05	2	179	2	28202068
Pubmed	Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion.	KMT2A AFF1	2.63e-05	2	179	2	38029383
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	ATG5 CNOT10 IKBKG ATG14 RB1CC1 CCNT1 VPS52 TBK1 KMT2A PDCD10 MED12	2.74e-05	457	179	11	32968282
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C9 OR13C2	2.85e-05	12	179	3	12906860
Pubmed	USP13 interacts with cohesin and regulates its ubiquitination in human cells.	PRPF31 STAG1 SMC1A	2.85e-05	12	179	3	33334891
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	VIL1 CDC42BPA GATAD2A UGGT1 SPTBN1 PACSIN3 FAM91A1 APOB TRIP12 FBXO30 IQGAP1 SCAF1 ACAD11 TCERG1 CTCF AGL ZNF451 TBK1 STON2 KMT2A	2.89e-05	1371	179	20	36244648
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NEBL ETF1 IRAK1 TACC2 OCRL CCNT1 ALMS1 TCERG1 CTCF UBTF CEP44 RRP12 ZNF638 KMT2A PRR14L HERC5	2.91e-05	934	179	16	33916271
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UGGT1 SPTBN1 TRIP12 TASOR2 IQGAP1 CTCF UBTF RRP12 ZNF638 KMT2A ATM MED12 HERC5	3.71e-05	653	179	13	22586326
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ATG5 VIL1 DENND4A CNOT10 PSMA2 SMC1A UGGT1 RALGPS2 PACSIN3 RB1CC1 IQGAP1 MRPS7 TIAM1 FRMD6 RRP12 ASPM MRPS9 STYXL1 PDCD10	3.82e-05	1284	179	19	17353931
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	CCNT1 KMT2A AFF1	4.68e-05	14	179	3	20854876
Pubmed	LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.	ATG5 ATG14 RB1CC1	5.83e-05	15	179	3	30245008
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	NRAP NEBL CYP2E1 CRTAC1 TACC2 FRMD4A SLF2 RRP12 CFAP70 PHYHIPL	6.33e-05	415	179	10	16385451
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NOL4 IKBKG IRAK1 RB1CC1 PALB2 DENND4C ALMS1 CEP44 TBK1 MED12	6.72e-05	418	179	10	34709266
Pubmed	KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.	NRAP NEB IQGAP1	7.15e-05	16	179	3	24960163
Pubmed	Gene expression analysis of the embryonic subplate.	NEBL ZNF521 CRTAC1 FRMD4A GNAI2 ALAS2 CDH9	7.44e-05	196	179	7	21862448
Interaction	HECTD1 interactions	PRPF31 ERCC6 ZNF695 GATAD2A RNPC3 SMC1A TPTE2 ATG14 TACC2 TRIP12 IQGAP1 NEK4 MRPS7 ACAD11 TCERG1 UBTF RRP12 SCAPER ASPM STYXL1 IGSF1 METTL15 IQGAP3 MED12 HERC5	1.26e-06	984	174	25	int:HECTD1
Interaction	MED4 interactions	CNOT10 PSMA2 TTLL5 TPTE2 NMRAL1 FAM91A1 DENND4C ODF2L ALMS1 ACAD11 FRMD6 TBK1 RECQL5 ZNF638 MED12	8.86e-06	450	174	15	int:MED4
Interaction	HDAC1 interactions	ERCC6 CDC42BPA GATAD2A STAG1 SMC1A ZNF521 IKBKG IRAK1 RB1CC1 PALB2 DENND4C IQGAP1 TBC1D32 ALMS1 CTCF UBTF CEP44 TBK1 ZNF638 KMT2A AFF1 ATM CABIN1 MED12 HERC5	1.01e-05	1108	174	25	int:HDAC1
Interaction	SH3PXD2A interactions	ATG5 DENND4A RALGPS2 FAM110A DENND4C NEK4 TIAM1 ZNF638	1.56e-05	128	174	8	int:SH3PXD2A
Interaction	LGR4 interactions	CDC42BPA POTEF TPTE2 UGGT1 RFWD3 IQGAP1 AGL RRP12 ZNF638 KMT2A IQGAP3	1.81e-05	262	174	11	int:LGR4
Interaction	KRT38 interactions	ATG5 CNOT10 FAM110A RFWD3 ODF2L ALMS1 ASPM PRR14L IQGAP3	1.91e-05	172	174	9	int:KRT38
Interaction	TRIM52 interactions	TTLL5 FAM91A1 APP ALMS1 ASPM PRR14L IQGAP3 ZNF445	2.06e-05	133	174	8	int:TRIM52
Interaction	YWHAB interactions	ATG5 PRPF31 DENND4A CDC42BPA ARHGAP23 POTEF SPTBN1 RALGAPB RALGPS2 RB1CC1 APP NEB TRIP12 RNF43 DENND4C IQGAP1 NEK4 TIAM1 BAIAP2L1 FRMD6 CEP95 ZNF638 KMT2A	2.19e-05	1014	174	23	int:YWHAB
Interaction	HECW2 interactions	ERCC6 CNOT10 ETF1 BAIAP2L1 XIRP2 SCAPER ZNF638 MRPS9 KMT2A CABIN1 MED12 HERC5	2.45e-05	322	174	12	int:HECW2
Interaction	ZNF460 interactions	NOL4 MRPS7 TINAG UBTF ASPM TRIM55 MRPS9 ZNF445	2.69e-05	138	174	8	int:ZNF460
Interaction	DENND1A interactions	ATG5 DENND4A RALGPS2 FAM110A DENND4C TIAM1 ZNF638	2.76e-05	101	174	7	int:DENND1A
Interaction	LMCD1 interactions	IKBKG APP TCERG1 TRIM55	4.98e-05	24	174	4	int:LMCD1
Interaction	ATG16L1 interactions	ATG5 DENND4A GATAD2A CNOT10 SMC1A TTLL5 IKBKG CCDC168 OCRL RB1CC1 APP TRIP12 DENND4C BAIAP2L1 TCERG1 CEP95 UBTF CEP44 TBK1 RRP12 ZNF638 MRPS9 ATM FMNL1	6.30e-05	1161	174	24	int:ATG16L1
Interaction	RTKN interactions	DENND4A RALGPS2 FAM110A APP DENND4C TIAM1 ZNF638	6.35e-05	115	174	7	int:RTKN
Interaction	SASH1 interactions	SPTBN1 IKBKG IRAK1 OAS2 AFF1	7.01e-05	50	174	5	int:SASH1
Interaction	RHOF interactions	CDC42BPA SPTBN1 ETF1 RALGAPB PACSIN3 FAM91A1 DENND4C IQGAP1 POTEE FAT1 VPS52 TIAM1 BAIAP2L1 STON2 IQGAP3 FMNL1 VPS13B	7.68e-05	673	174	17	int:RHOF
Interaction	YWHAH interactions	DENND4A CDC42BPA POTEF SPTBN1 RALGAPB RALGPS2 RB1CC1 TRIP12 DENND4C IQGAP1 IFIH1 FRMD4A ALMS1 TIAM1 BAIAP2L1 TCERG1 FRMD6 SLF2 CEP95 TBK1 ZNF638 KMT2A ALDH7A1	7.87e-05	1102	174	23	int:YWHAH
Interaction	HDAC4 interactions	DENND4A STAG1 ARHGAP23 SPTBN1 ETF1 RALGPS2 PACSIN3 FAM110A APP DENND4C IQGAP1 VPS52 TIAM1 TCERG1 CEP70 ZNF638 ATM PDCD10	8.13e-05	744	174	18	int:HDAC4
Interaction	PPM1H interactions	DENND4A RALGPS2 FAM91A1 FAM110A DENND4C TIAM1 ZNF638	9.71e-05	123	174	7	int:PPM1H
Interaction	TMOD4 interactions	APP NEB ACAD11 ALAS1	1.08e-04	29	174	4	int:TMOD4
Cytoband	1p13.3	NBPF4 NBPF6 NBPF5P VAV3 MYBPHL	7.82e-06	69	179	5	1p13.3
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEE POTEA	6.67e-05	13	114	3	685
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	3.94e-04	23	114	3	662
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C9 OR13C2	3.94e-04	23	114	3	162
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF567 ZNF695 ZSCAN5A ZNF549 ZNF521 ZNF675 ZNF37A CTCF ZNF451 SCAPER ZNF454 ZNF681 ZNF445	5.93e-04	718	114	13	28
GeneFamily	Cohesin complex	STAG1 SMC1A	1.08e-03	8	114	2	1060
GeneFamily	Autophagy related	ATG5 ATG14 RB1CC1	1.16e-03	33	114	3	1022
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP23 SPTBN1 RALGPS2 PLEKHD1 TIAM1 VAV3	1.96e-03	206	114	6	682
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 ABCA12 PCLO APOB NEB LRP1B FAT1 XIRP2 PIK3C2G	5.57e-08	184	177	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 ABCA12 PCLO APOB NEB LRP1B FAT1 XIRP2 PIK3C2G	5.57e-08	184	177	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 ABCA12 PCLO APOB NEB LRP1B FAT1 XIRP2 PIK3C2G	5.57e-08	184	177	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 APP UGCG KMT2A FILIP1L	1.14e-07	200	177	9	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEBL PPP1R14C CRTAC1 TACC2 RNF43 ITGB6 ATP8A1 CEP70	7.28e-07	183	177	8	6847c1252d6bb105524f812658112517fd351eab
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL IGSF1 RAB3B	8.23e-07	186	177	8	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL IGSF1 RAB3B	8.23e-07	186	177	8	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL RAB3B	8.92e-07	188	177	8	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL RAB3B	8.92e-07	188	177	8	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL RAB3B	8.92e-07	188	177	8	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL RAB3B	9.29e-07	189	177	8	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C ITGB6 XIRP2 TRIM55 MYBPHL RAB3B	9.29e-07	189	177	8	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	ARHGAP23 PPP1R14C TACC2 ITGB6 FAT1 FRMD6 PTPRZ1 ALDH7A1	9.66e-07	190	177	8	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL CCDC30 PCLO RALGPS2 FAT1 VAV3 SPAG16 PHYHIPL	1.22e-06	196	177	8	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SLF1 SPTBN1 SH2D3C OAS2 APP UGCG KMT2A HERC5	1.42e-06	200	177	8	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	PLK2 ZNF521 CRTAC1 APP LRP1B FRMD4A KIAA1549L FILIP1L	1.42e-06	200	177	8	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	ATG14 RNF43 PALB2 IFIH1 ATP8A1 ZNF451	5.48e-06	111	177	6	dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HTR1F E2F2 STON2 ASPM PADI6 MYBPHL IQGAP3	5.64e-06	171	177	7	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C NEB XIRP2 TRIM55 MYBPHL	5.86e-06	172	177	7	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP NEBL PPP1R14C NEB XIRP2 TRIM55 MYBPHL	5.86e-06	172	177	7	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LRRIQ3 ZNF521 FRMD4A ATP8A1 XIRP2 UGCG VAV3	7.61e-06	179	177	7	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	GDPD1 RNPC3 ARMCX4 FBXO30 CCNT1 SNRNP48 ZNF681	9.10e-06	184	177	7	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	GDPD1 RNPC3 ARMCX4 FBXO30 CCNT1 SNRNP48 ZNF681	9.43e-06	185	177	7	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	E17.5-Epithelial-alveolar_epithelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDGFA PPP1R14C APP ITGB6 IQGAP1 TINAG ATP8A1	9.77e-06	186	177	7	a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEBL CRTAC1 TACC2 ITGB6 ATP8A1 PIK3C2G CEP70	1.01e-05	187	177	7	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	ARHGAP23 SH2D3C ZNF521 APP FRMD6 STON2 VAV3	1.01e-05	187	177	7	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C XIRP2 TRIM55 MYBPHL IGSF1 RAB3B	1.08e-05	189	177	7	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C XIRP2 TRIM55 MYBPHL IGSF1 RAB3B	1.08e-05	189	177	7	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL PPP1R14C OCRL APP PTPRZ1 PHYHIPL RAB3B	1.08e-05	189	177	7	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	ARHGAP23 ITGB6 TIAM1 FRMD6 PTPRZ1 STON2 ALDH7A1	1.12e-05	190	177	7	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 APOB RB1CC1 IQGAP1 CTCF UBTF FILIP1L	1.16e-05	191	177	7	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 APOB RB1CC1 IQGAP1 CTCF UBTF FILIP1L	1.16e-05	191	177	7	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 APOB RB1CC1 IQGAP1 CTCF UBTF FILIP1L	1.16e-05	191	177	7	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	ARHGAP23 PPP1R14C ITGB6 FAT1 FRMD6 PTPRZ1 ALDH7A1	1.20e-05	192	177	7	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	PND03-Epithelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFA PPP1R14C APP ITGB6 TINAG ATP8A1 BAIAP2L1	1.20e-05	192	177	7	d8c23693f690d4d568585537bbfedda05d505b3d
ToppCell	Epithelial\|World / shred on cell class and cell subclass (v4)	PDGFA PPP1R14C APP ITGB6 TINAG ATP8A1 BAIAP2L1	1.20e-05	192	177	7	13a3553d9a7c78535679d23d454c63fd08f7d218
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFA PPP1R14C APP ITGB6 IQGAP1 TINAG ATP8A1	1.24e-05	193	177	7	54506c0da2f219f472b95e8935a78b657a8dec41
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFA PPP1R14C APP ITGB6 IQGAP1 TINAG ATP8A1	1.24e-05	193	177	7	2d42721fac1bee294ede47d609bebb3e7d36bf0c
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DENND4A UGGT1 E2F2 FBXO30 FRMD4A ZNF451 ALAS2	1.24e-05	193	177	7	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL CCDC30 PCLO LRP1B ITGB6 VAV3 SPAG16	1.33e-05	195	177	7	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL PPP1R14C RALGPS2 ITGB6 FAT1 BAIAP2L1 SPAG16	1.42e-05	197	177	7	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	ZNF567 RB1CC1 FBXO30 RNF103 XIRP2 ZNF451 VPS13B	1.46e-05	198	177	7	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNPC3 CCNT1 ODF2L ZNF451 ANKRD36 ATM VPS13B	1.51e-05	199	177	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	APP IQGAP1 ODF2L FAT1 CEP95 KMT2A CABIN1	1.51e-05	199	177	7	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PDGFA PPP1R14C RNF43 ITGB6 FAT1 PTPRZ1 ALDH7A1	1.56e-05	200	177	7	592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 SLF1 SPTBN1 SH2D3C ZNF521 OAS2 APP	1.56e-05	200	177	7	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFA PPP1R14C RNF43 ITGB6 FAT1 PTPRZ1 ALDH7A1	1.56e-05	200	177	7	8cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PDGFA PPP1R14C RNF43 ITGB6 FAT1 PTPRZ1 ALDH7A1	1.56e-05	200	177	7	61811380d9252f12f27b7ad4752380b52692677f
ToppCell	primary_visual_cortex\|World / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRTAC1 TIAM1 FRMD6 KMT2A RAB3B FMNL1	2.15e-05	141	177	6	605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RNPC3 RIIAD1 TACC2 PLEKHD1 LRP1B PIK3C2G	4.08e-05	158	177	6	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFA PPP1R14C PLEKHD1 TINAG ATP8A1 USP33	4.69e-05	162	177	6	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	facs-Heart-RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 PPP1R14C PACSIN3 XIRP2 ALAS2 MYBPHL	4.69e-05	162	177	6	3a61eda548afa2a41bdf6293d1050103dc210e52
ToppCell	facs-Heart-RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 PPP1R14C PACSIN3 XIRP2 ALAS2 MYBPHL	4.69e-05	162	177	6	593939be9d38690c89c31d4c58e351de26cbf9ab
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFA PPP1R14C PLEKHD1 TINAG ATP8A1 USP33	4.69e-05	162	177	6	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLF1 ZNF451 RRP12 AFF1 ALAS2 FMNL1	4.85e-05	163	177	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	Ionocyte-iono-1\|World / Class top	DENND4A FASTKD1 ZNF521 IQGAP1 FRMD4A AGL	5.93e-05	169	177	6	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	severe-HSPC\|World / disease stage, cell group and cell class	HTR1F CDC42BPA ZNF521 PTGES3L STON2 CEP70	5.93e-05	169	177	6	b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PPP1R14C APOB PLEKHD1 TINAG ATP8A1 BAIAP2L1	6.13e-05	170	177	6	d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNPC3 OAS2 IFIH1 HERC5 PDCD1LG2 ZNF445	6.13e-05	170	177	6	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEBL PPP1R14C RNF43 ITGB6 ATP8A1 MYBPHL	6.75e-05	173	177	6	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GDPD1 RNF166 ERCC6 FASTKD1 ODF2L RNF103	7.19e-05	175	177	6	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	COVID-19-lung-RBC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DENND4A E2F2 FAM110A ZNF451 ALAS2 ALOX12	7.19e-05	175	177	6	4c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R14C PLEKHD1 ITGB6 PTPRZ1 IGSF1 CNGA2	7.42e-05	176	177	6	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	VIL1 PDGFA PTGES3L XIRP2 STON2 ALOX12	7.66e-05	177	177	6	0830944c43de300815831a9e2b2fce40965e7d12
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 ARHGAP23 E2F2 FBXO30 RRP12 VCPKMT	7.66e-05	177	177	6	f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	VIL1 PDGFA PTGES3L XIRP2 STON2 ALOX12	7.66e-05	177	177	6	e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	7.90e-05	178	177	6	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCLO UGT3A1 ALDH8A1 TINAG PHYHIPL CDH9	7.90e-05	178	177	6	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	7.90e-05	178	177	6	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	7.90e-05	178	177	6	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	7.90e-05	178	177	6	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP1R14C APOB M1AP TINAG ATP8A1 BAIAP2L1	8.15e-05	179	177	6	bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DENND4A FAM110A FRMD4A CFAP70 RAB3B PDCD1LG2	8.15e-05	179	177	6	87f608b137aae34572b150492a83a3a127cff40b
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	UGT3A1 ALDH8A1 FAT1 TINAG PHYHIPL CDH9	8.40e-05	180	177	6	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R14C OCRL APP TIAM1 PTPRZ1 RAB3B	8.40e-05	180	177	6	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	8.66e-05	181	177	6	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R14C PLEKHD1 ITGB6 TINAG BAIAP2L1 CNGA2	8.66e-05	181	177	6	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	18-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	PLK2 PDGFA PPP1R14C RNF43 ITGB6 PDCD1LG2	8.66e-05	181	177	6	33938e6521712058312879f84f4ae381c2bfc379
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 NEBL PPP1R14C ITGB6 FRMD4A PHYHIPL	8.66e-05	181	177	6	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCLO UGT3A1 ALDH8A1 TINAG PHYHIPL CDH9	8.66e-05	181	177	6	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DENND4A E2F2 ATG14 FBXO30 ZNF451 ALAS2	8.93e-05	182	177	6	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DENND4A E2F2 ATG14 FBXO30 ZNF451 ALAS2	8.93e-05	182	177	6	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C PACSIN3 PTGES3L NEB XIRP2	8.93e-05	182	177	6	edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 NEBL PPP1R14C FRMD4A FAT1 PHYHIPL	9.20e-05	183	177	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 NEBL PPP1R14C ITGB6 FAT1 PHYHIPL	9.20e-05	183	177	6	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	NEBL ALDH8A1 FAT1 TINAG PHYHIPL CDH9	9.48e-05	184	177	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 IQGAP1 SLF2 ZNF638 KMT2A FILIP1L	9.48e-05	184	177	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	normal-na-Lymphocytic-lymphocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ERCC6 CCDC30 E2F2 PALB2 SLF2 LRRC37B	9.48e-05	184	177	6	2c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	SPTBN1 ZNF521 APP FRMD6 STON2 VAV3	9.76e-05	185	177	6	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIL1 PCLO RIIAD1 CASC2 RNF43 RAB3B	9.76e-05	185	177	6	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C PACSIN3 XIRP2 MYBPHL RAB3B	9.76e-05	185	177	6	9ef66bf63ed728cbf3044520a2a1625a9d5863a4
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 SPTBN1 IQGAP1 ZNF638 VAV3 FILIP1L	9.76e-05	185	177	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	SPTBN1 ZNF521 APP FRMD6 STON2 VAV3	9.76e-05	185	177	6	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP PPP1R14C PACSIN3 XIRP2 MYBPHL RAB3B	9.76e-05	185	177	6	2148b78db2afaf29b01d604d314d6061179e2663
ToppCell	E17.5-Epithelial\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDGFA PPP1R14C APP IQGAP1 TINAG ATP8A1	1.04e-04	187	177	6	fdabe716ce67f2eede90548198cbe20bbf693570
Drug	Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A	CDC42BPA PDGFA SPTBN1 IQGAP1 CCNT1 UBTF UGCG KMT2A PRR14L CABIN1	2.47e-06	192	175	10	4104_DN
Disease	female breast cancer (is_implicated_in)	PALB2 CTCF ATM	1.12e-05	8	175	3	DOID:0050671 (is_implicated_in)
Disease	Growth Deficiency and Mental Retardation with Facial Dysmorphism	SMC1A KMT2A	3.50e-05	2	175	2	C1854630
Disease	colorectal cancer (is_implicated_in)	ERCC6 CYP2E1 LRP1B RNF43 FAT1 ATM	8.73e-05	121	175	6	DOID:9256 (is_implicated_in)
Disease	muscle measurement	PLK2 NEB	2.08e-04	4	175	2	EFO_0004515
Disease	Premature aging syndrome	ERCC6 APP	2.08e-04	4	175	2	C0231341
Disease	mean corpuscular hemoglobin concentration	VIL1 DENND4A GATAD2A POTEF ALDH8A1 E2F2 NEB RNF43 NEK4 CTCF UBTF TBK1 UGCG ZNF638 AFF1 ALAS2 VPS13B	3.28e-04	1105	175	17	EFO_0004528
Disease	carnosine measurement	ZNF675 FRMD4A ZNF681	3.79e-04	24	175	3	EFO_0010470
Disease	Malignant tumor of breast	RB1CC1 PALB2 ATM	5.40e-04	27	175	3	cv:C0006142
Disease	Breast neoplasm	RB1CC1 PALB2 ATM	5.40e-04	27	175	3	cv:C1458155
Disease	Familial cancer of breast	RB1CC1 PALB2 ATM	5.40e-04	27	175	3	cv:C0346153
Disease	beta-Ala-His dipeptidase measurement	ZNF675 ZNF681	9.57e-04	8	175	2	EFO_0008033
Disease	diastolic blood pressure, self reported educational attainment	PIK3C2G RERGL	9.57e-04	8	175	2	EFO_0004784, EFO_0006336
Disease	Cornelia De Lange Syndrome	SMC1A KMT2A	9.57e-04	8	175	2	C0270972
Disease	triglyceride measurement, response to selective serotonin reuptake inhibitor	NEBL FRMD4A VAV3	1.07e-03	34	175	3	EFO_0004530, EFO_0005658
Disease	Headache, glucose measurement	GATAD2A ZNF638	1.23e-03	9	175	2	EFO_0004468, HP_0002315
Disease	Nephroblastoma	DIS3L2 PALB2 CTCF	1.27e-03	36	175	3	C0027708
Disease	level of Triacylglycerol (51:3) in blood serum	GATAD2A APOB	1.53e-03	10	175	2	OBA_2045163
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA PDCD10	1.86e-03	11	175	2	DOID:0060669 (implicated_via_orthology)
Disease	visual epilepsy (is_implicated_in)	APP ASPM	1.86e-03	11	175	2	DOID:11832 (is_implicated_in)
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	TBC1D32 SCAPER	1.86e-03	11	175	2	DOID:1935 (implicated_via_orthology)
Disease	quality of life during menstruation measurement, dysmenorrheic pain measurement	RB1CC1 VPS13B	1.86e-03	11	175	2	EFO_0007889, EFO_0009366
Disease	middle cerebral artery infarction (biomarker_via_orthology)	ERCC6 CYP2E1 APP PTPRZ1	2.32e-03	93	175	4	DOID:3525 (biomarker_via_orthology)
Disease	Adenocarcinoma of large intestine	RNF43 NEK4 TBK1 ATM	2.60e-03	96	175	4	C1319315
Disease	pulmonary emphysema (implicated_via_orthology)	ITGB6 BLOC1S6	2.61e-03	13	175	2	DOID:9675 (implicated_via_orthology)
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	2.61e-03	13	175	2	DOID:3121 (is_implicated_in)
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	PLK2 STAG1 NEK4 TTC21B ZNF638 MYBPHL SPAG16 METTL15	2.69e-03	398	175	8	EFO_0003756, EFO_0003888, EFO_0004337
Disease	Adenoid Cystic Carcinoma	SMC1A FAT1 ASPM ATM	3.01e-03	100	175	4	C0010606
Disease	breast carcinoma	PLK2 NRAP GATAD2A NEBL CCDC30 FAM91A1 TACC2 PALB2 TASOR2 FRMD4A BAIAP2L1 ZNF37A PADI6 FILIP1L	3.13e-03	1019	175	14	EFO_0000305
Disease	sleep duration, triglyceride measurement	STAG1 APOB AFF1 METTL15	3.47e-03	104	175	4	EFO_0004530, EFO_0005271
Disease	Influenza	OAS2 IFIH1 HERC5	3.66e-03	52	175	3	C0021400
Disease	Prostatic Neoplasms	CYP2E1 LRP1B RNF43 PALB2 VPS52 CTCF KMT2A VAV3 ATM MED12	3.88e-03	616	175	10	C0033578
Disease	focal segmental glomerulosclerosis	CCDC30 ALMS1	3.97e-03	16	175	2	EFO_0004236
Disease	triglycerides in medium HDL measurement	STAG1 APOB AFF1	4.07e-03	54	175	3	EFO_0022321
Disease	Necrosis	ATG5 CYP2E1 APP	4.29e-03	55	175	3	C0027540
Disease	Mammary Neoplasms	PDGFA RB1CC1 PLEKHD1 PALB2 MRPS7 CTCF GNAI2 ATM MED12	4.37e-03	527	175	9	C1458155
Disease	Malignant neoplasm of breast	CATSPERE ERCC6 PDGFA TACC2 RB1CC1 PLEKHD1 PALB2 MRPS7 AFF1 GNAI2 ATM CNGA2 MED12 VPS13B	4.96e-03	1074	175	14	C0006142
Disease	cognitive behavioural therapy	NEB TCERG1 VAV3	4.98e-03	58	175	3	EFO_0007820
Disease	Myeloid Leukemia	SMC1A KMT2A	5.03e-03	18	175	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC1A KMT2A	5.03e-03	18	175	2	C0023466
Disease	cognitive function measurement	ATG5 PLK2 DENND4A CNOT10 ZNF521 APP LRP1B FRMD4A ALMS1 RERGL TTC21B ZNF638 VAV3 GNAI2 SPAG16 METTL15 CDH9	5.24e-03	1434	175	17	EFO_0008354
Disease	cholesterol in chylomicrons and extremely large VLDL measurement	STAG1 APOB AFF1	5.48e-03	60	175	3	EFO_0021898
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	PALB2 ATM	5.60e-03	19	175	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	PALB2 ATM	5.60e-03	19	175	2	C2936783

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKHSVAQRDYEKAIK	TTC21B	891	Q7Z4L5
SKAHLEKVRSYVKRA	ALDH8A1	331	Q9H2A2
IHTVLKRKVYSSNEK	CATSPERE	161	Q5SY80
LRKQHSYIEQGKKCR	CTCF	456	P49711
KKIQKEKSHSYRTDN	TBC1D32	141	Q96NH3
LYHKRQASRIAKEEV	HTR1F	211	P30939
LYSRAQRHQEKKEKI	ATG14	151	Q6ZNE5
KYVRAEQKDRQHTLK	APP	496	P05067
SIHDEVVNRLKKAYA	ALDH7A1	341	P49419
SLLYHDNVISKKVRD	ABCA12	486	Q86UK0
ATVNIKHKEGIYSKR	ALMS1	3326	Q8TCU4
KHKEGIYSKRVVTKA	ALMS1	3331	Q8TCU4
TSGKKKAVVIRHLYN	CEP44	166	Q9C0F1
KAESKSRVLKTELHY	ANKRD36	1656	A6QL64
KVSLKEYRAKHAEEL	CCNT1	386	O60563
RVSYLTLVTDKVKKH	ATG5	41	Q9H1Y0
RSAKVVYILEKKHSR	DIS3L2	231	Q8IYB7
GSYTHKKEKLIRDVA	ERCC6	601	Q03468
FVQRKYRATICAKHK	ASPM	2436	Q8IZT6
SVAAENHRKVKTYLN	ARMCX4	2111	Q5H9R4
RLAETSKYKEITLKH	ATP8A1	581	Q9Y2Q0
QRIAFKKKLYAHEVV	ACAD11	656	Q709F0
SKKISLKYTAARLHE	IQGAP1	1556	P46940
QEIKSAHKIAKRYSS	DENND4A	741	Q7Z401
KVCHSKVRALKTAYD	DENND4A	781	Q7Z401
ELRQYKALVHSQAKE	NBPF4	91	Q96M43
ALKKASKVYKQRLDH	ODF2L	241	Q9ULJ1
TLKVKASYRKINTHI	PDCD1LG2	116	Q9BQ51
GIDFKVKTVYRHEKR	RAB3B	56	P20337
NKKARHSDIVVLYAR	RFWD3	331	Q6PCD5
SHRKVIKNVAEVKEY	CYP2E1	231	P05181
ASFCNKVKKIRERYH	PIK3C2G	246	O75747
KVKKIRERYHAADVN	PIK3C2G	251	O75747
KVEHTSRLKAAFVKA	GATAD2A	451	Q86YP4
ADLKHAIQSKYKIAI	RB1CC1	26	Q8TDY2
SAIKRKEKDHYLLQV	FAT1	3501	Q14517
RSEDIHIIYIRKKKS	VCPKMT	211	Q9H867
KHQSQLREKKYLEDI	POTEF	666	A5A3E0
YRLVLHTSKEESKKA	PADI6	206	Q6TGC4
DKTKGVLISHRYKQL	LRP1B	4156	Q9NZR2
SASHYKLQVIKALKS	M1AP	301	Q8TC57
AEEYAALLTKHTRKV	NMRAL1	221	Q9HBL8
NAKKAHELASDIKYR	NRAP	321	Q86VF7
KIDEKKNDHTYRVFK	ALAS1	206	P13196
LRYRNNLVKHVKKDE	FAM91A1	46	Q658Y4
NLVKHVKKDERRYYE	FAM91A1	51	Q658Y4
VQNASAEYKRRTKHV	PCLO	4746	Q9Y6V0
AEYKRRTKHVQKSLN	PCLO	4751	Q9Y6V0
NRRALEHQKKEFVKY	PDCD10	156	Q9BUL8
NVTYKHREKQKVDLS	ITGB6	771	P18564
TLVKHRRDGKQYVIK	NEK4	21	P51957
LEADKAKYVKSLHVA	FAM110A	46	Q9BQ89
KEADAVSYKISREHK	HERVK_113	911	P63132
SEEKRKLAQLQVAYH	IKBKG	221	Q9Y6K9
IEVNSHKRASEKYKD	LRRC37B	926	Q96QE4
YYAAISETKVKKRHV	MED12	166	Q93074
KKVSELVKRYNREHL	GDPD1	161	Q8N9F7
VNKALKQKSDIEHYR	KIAA1549L	1391	Q6ZVL6
LYNVKRHSLEVRVKD	GPR101	226	Q96P66
KHREKELKDRQQIYC	ALOX12	126	P18054
YSLRNKDVKEAVKHL	OR13C5	296	Q8NGS8
AYDHSRVKLAQLAEK	PTPRZ1	1761	P23471
YSLRNKDVKEAVKHL	OR13C2	296	Q8NGS9
QRAVKTHGARTKYLK	IRAK1	421	P51617
SILRTYGEEKHAKKI	METTL15	221	A6NJ78
YTSQKNERHKIVKEI	OAS2	421	P29728
KEADAVSYKISREHK	ERVK-6	911	Q9BXR3
KKQDHTYRVFKTVNR	ALAS2	156	P22557
SKEKRQKLEAYQHLF	IQGAP3	946	Q86VI3
KKHKAYLRSAAIEEE	HERC5	656	Q9UII4
RSKEEVTSHKYQHEK	PALB2	541	Q86YC2
KHQSQLREKKYLEDI	POTEE	666	Q6S8J3
QFYLDRKQSKSKIHA	FRMD4A	316	Q9P2Q2
TASEAHLKYIKEAVR	FRMD6	211	Q96NE9
AAETNNVYKKHRILK	ATM	1426	Q13315
QYTLDAKRKHVAEAI	APOB	246	P04114
LHLRYQKDKKGISTS	APOB	3986	P04114
RVEDLEKSFYHKKTI	IGSF1	261	Q8N6C5
RYQTEHKNKLESLEK	BAIAP2L1	121	Q9UHR4
KKSKARYLEEHSAQQ	CABIN1	956	Q9Y6J0
KHLTEDKANKRLAYV	E2F2	236	Q14209
KEIEVQHKRYDAILK	CCDC122	221	Q5T0U0
ESKIRKIHTQRQYKE	CEP70	221	Q8NHQ1
NELDKVVEKHKESYR	FILIP1L	141	Q4L180
EQLKHAVVKIVRDKY	CFAP70	571	Q5T0N1
HRTAEEKKYVSEKQL	CASC2	21	Q6XLA1
QKTSLLKNAEYVRDH	FASTKD1	81	Q53R41
TRVAVYIAKDHLDKK	IFIH1	336	Q9BYX4
KRKYDEHVKSNQELS	CCDC30	456	Q5VVM6
QEIKTAHKLAKRCYT	DENND4C	751	Q5VZ89
TTLVKKEYEHNKRLQ	CEP95	626	Q96GE4
IYTRLHLNKKATDKQ	UGCG	31	Q16739
AEAKHYHAKLVNIRK	BLOC1S6	106	Q9UL45
DLAHIQKAATVYKTK	MYBPHL	236	A2RUH7
VLLEHRFYKEKSKSV	DEF8	196	Q6ZN54
KSTDRKQTLLHYLVK	FMNL1	871	O95466
RHLKKTSKEAVGVYR	KMT2A	3821	Q03164
AKVVLYTKKSGAHLR	CRTAC1	461	Q9NQ79
NIIRYSTENHRKKKQ	CCDC168	2171	Q8NDH2
SKNAVHRVLKAVYDS	CCDC168	2841	Q8NDH2
ADHLKKCSYNVVEKR	FBXO30	701	Q8TB52
AIKQHVKRATDTYNL	EFCAB3	326	Q8N7B9
ASRIKTIYNAEHLKE	RNF103	211	O00237
NKRHDVLSKLKEYEQ	SCAPER	636	Q9BY12
HAAKKLDREEKSLYI	CDH9	111	Q9ULB4
KEEKYIRQQKAHTIS	PRR14L	1401	Q5THK1
RLKEVEASKKSYHAA	PACSIN3	146	Q9UKS6
KTKAQYEQTLAELHR	PACSIN3	201	Q9UKS6
IRAEVLSHYIKTAKK	RALGPS2	116	Q86X27
HVFDSKKRTALIKAV	POTEA	126	Q6S8J7
RHQQGKVTVKYDRKE	PPP1R14C	66	Q8TAE6
YSLRNKDVKEAVKHL	OR13C9	296	Q8NGT0
SKDRITHYFIDLNKK	PHYHIPL	76	Q96FC7
EAVKRKQFEKYHAAS	MRPS7	116	Q9Y2R9
HLKYNEKSVSVTKAL	RERGL	6	Q9H628
ELRQYKALVHSQAKE	NBPF5P	91	Q86XG9
ELRQYKALVHSQAKE	NBPF6	91	Q5VWK0
TRIANEKYLRTHKEV	RIIAD1	31	A6NNX1
VDKATHVEKQLSSYK	RNF166	81	Q96A37
LNKRKDTKEIYTHFT	GNAI2	311	P04899
VYKNQKAHVRIELKE	RNF43	176	Q68DV7
YRTKVKDLVARIHGK	SLF2	1136	Q8IX21
SKTRHRKFKEIQVPY	CDC42BPA	1346	Q5VT25
IRKHAGQKRTYKAIS	NOL4	126	O94818
VERGLHSKAKYKKVQ	OCRL	301	Q01968
ESKAHGVQKKAYRVL	RRP12	781	Q5JTH9
IHSLRIDRVTYKEKK	STON2	496	Q8WXE9
EYSTQSLVKKHKDVA	SPTBN1	776	Q01082
KKDIAIKYSRTLNKH	AFF1	1066	P51825
KDTKKLRDNYIHTLQ	CNGA2	206	Q16280
IEAAKSKIHQYKVRA	CNOT10	211	Q9H9A5
LYKASVLKKVADIHR	RECQL5	596	O94762
KTFYKNSDLIKHQRI	ZNF37A	306	P17032
EIRKVEKRATYVHKD	XIRP2	3086	A4UGR9
KEALKTGVDLRHYSK	VPS52	71	Q8N1B4
KFKEHQEKYSRSVVS	ZNF567	86	Q8N184
YTCSEAQKAAHKRKI	TDP1	46	Q9NUW8
KKAAATTAQEYLKTH	VIL1	671	P09327
KRKDHIDYQKDKVAL	ZNF451	66	Q9Y4E5
QKRIKKHFDSYIETA	UGT3A1	86	Q6NUS8
ALIKKYSDHLENVSK	TRIM55	246	Q9BYV6
AVVEKNHTEKKTYRC	ZNF695	256	Q8IW36
EKAFIYKNKLVEHQR	ZNF549	591	Q6P9A3
RIYVKNLAKHVQEKD	RNPC3	421	Q96LT9
KKKLVGSHRLSIYED	TIAM1	1311	Q13009
HHRSVKVAKVEYVRK	PDGFA	146	P04085
RKTAKAEAIVYKHGS	MRPS9	276	P82933
HVITALRVKKKNNEY	STYXL1	46	Q9Y6J8
YRSKKLIQESDQHLK	TCERG1	1031	O14776
KNSVYIHKAATRRIK	PLEKHD1	421	A6NEE1
KYLKKLHTQERAVEE	SCAF1	1206	Q9H7N4
LISKKLNDYRKVSHS	ARHGAP23	821	Q9P227
LAVKHSNEKKVYRCT	ZNF521	741	Q96K83
LKHYKQAADKAREDL	SPAG16	171	Q8N0X2
KEADAVSYKISREHK	ERVK-8	911	P63133
ELNIIHKFIRDKYSK	PRPF31	106	Q8WWY3
KKVFTYRGSLKEHQR	ZSCAN5A	446	Q9BUG6
KQKSILYDERSVHKV	PSMA2	51	P25787
VKAEEDTQFNYHRKK	SMC1A	176	Q14683
YHRKKNIAAERKEAK	SMC1A	186	Q14683
TLEENQVKKYHRLKE	SMC1A	366	Q14683
QVKKYHRLKEEASKR	SMC1A	371	Q14683
RQDKKTVHSYLEKFL	STAG1	1016	Q8WVM7
RVKKEEQRYQALKVH	TACC2	2866	O95359
HVRRKQKITDIVNKY	RALGAPB	1456	Q86X10
KSEKYKNCTHLIAER	SLF1	36	Q9BQI6
QSSKLTKHKRIYTCE	ZNF675	211	Q8TD23
ETHAKKKFLELNQYR	ZNF445	561	P59923
LTYTKAVTKNVRHKL	VPS13B	1451	Q7Z7G8
KIIHTREKLNEYKEC	ZNF681	301	Q96N22
NQKIHIKEKRYECRE	ZNF454	206	Q8N9F8
RYEKFDKVLTALSHK	SH2D3C	836	Q8N5H7
VASYDSKIKKIVHSI	TPTE2	56	Q6XPS3
HLNKLKYNSTVKESR	TASOR2	2091	Q5VWN6
YKLRHDLKKTSITQQ	PLK2	396	Q9NYY3
ESEKYRKLQTHAVKL	TINAG	401	Q9UJW2
RISQSQKEHYKKLAE	UBTF	606	P17480
VEHYAELLKKVSTKR	PTGES3L	131	E9PB15
ARSVYHLEDIVRQKK	TRIP12	1746	Q14669
RAKNVHITKKSYTEV	SNRNP48	226	Q6IEG0
HKKAYIEINRKAAES	ZNF638	941	Q14966
LTHIYNKVRTGEKVK	UGGT1	571	Q9NYU2
KQHKKYRSVISDIFD	USP33	466	Q8TEY7
LNSKAKLHAALYERK	TTLL5	531	Q6EMB2
ERAVLRKDHQKKYGA	TBK1	186	Q9UHD2
KYNNEAKHIKILTRD	VAV3	711	Q9UKW4
EKRHNYVRKVAETAV	ETF1	196	P62495
VTVKRHGKAIKVSYD	AGL	1311	P35573
KVRSQEIYKRHCEEK	LRRIQ3	571	A6PVS8
ISSVKYKEEIKHATA	NEBL	621	O76041
KKSQAIASDVDYKHI	NEB	906	P20929
EKNKRATQILSDHVY	NEB	2676	P20929
SLHIAKVQSDREYKK	NEB	3306	P20929
HVAKIQSDREYKKEF	NEB	3551	P20929
KTVDLDRALHAYKLQ	NEB	4931	P20929
HVKYATKIASEKEYR	NEB	5961	P20929