Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of amyloid-beta clearance	ABCA7 LRP1 ROCK1	2.59e-05	8	162	3	GO:1900223
GeneOntologyBiologicalProcess	regulation of cell morphogenesis	OBSL1 CUL7 PTK2 TAOK2 CORO1A COCH PTPRD PALM3 PLXNB1 RASAL1 MOV10	2.79e-05	302	162	11	GO:0022604
Domain	-	EPHB3 EPHB4 PCSK2 CUL9 CUL7 NCCRP1 FBXO2 FBXO27	2.04e-07	73	160	8	2.60.120.260
Domain	Galactose-bd-like	EPHB3 EPHB4 PCSK2 CUL9 CUL7 NCCRP1 FBXO2 FBXO27	1.45e-06	94	160	8	IPR008979
Domain	F-box-assoc_dom	NCCRP1 FBXO2 FBXO27	1.21e-05	6	160	3	IPR007397
Domain	FBA	NCCRP1 FBXO2 FBXO27	1.21e-05	6	160	3	PF04300
Domain	FBA	NCCRP1 FBXO2 FBXO27	1.21e-05	6	160	3	PS51114
Domain	FBA	NCCRP1 FBXO2 FBXO27	1.21e-05	6	160	3	SM01198
Domain	fn3	EPHB3 EPHB4 TNC OBSL1 PTPRD TIE1 IGSF9B TNXB	7.88e-05	162	160	8	PF00041
Domain	Spectrin_repeat	DRP2 SPTBN5 PLEC UTRN	1.04e-04	29	160	4	IPR002017
Domain	SPEC	DRP2 SPTBN5 PLEC UTRN	1.55e-04	32	160	4	SM00150
Domain	Spectrin/alpha-actinin	DRP2 SPTBN5 PLEC UTRN	1.55e-04	32	160	4	IPR018159
Domain	PROTEIN_KINASE_TYR	EPHB3 EPHB4 FLT4 LMTK3 PTK2 TIE1	1.87e-04	97	160	6	PS00109
Domain	-	EPHB3 EPHB4 FLT4 EPM2A TNC OSCAR OBSL1 BCAN KIRREL2 PTPRD IGFBP7 TIE1 NFKB2 IGSF9B TNXB PLXNB1	1.88e-04	663	160	16	2.60.40.10
Domain	FN3	EPHB3 EPHB4 TNC OBSL1 PTPRD TIE1 IGSF9B TNXB	1.97e-04	185	160	8	SM00060
Domain	Cul7	CUL9 CUL7	2.18e-04	3	160	2	PF11515
Domain	CPH_domain	CUL9 CUL7	2.18e-04	3	160	2	IPR021097
Domain	FN3	EPHB3 EPHB4 TNC OBSL1 PTPRD TIE1 IGSF9B TNXB	3.23e-04	199	160	8	PS50853
Domain	Ig-like_fold	EPHB3 EPHB4 FLT4 EPM2A TNC OSCAR OBSL1 BCAN KIRREL2 PTPRD IGFBP7 TIE1 NFKB2 IGSF9B TNXB PLXNB1	3.79e-04	706	160	16	IPR013783
Domain	Growth_fac_rcpt_	EPHB3 EPHB4 TNC IGFBP7 TIE1 LRP1 TNXB	3.98e-04	156	160	7	IPR009030
Domain	DNA_pol_B	POLA1 POLE	4.33e-04	4	160	2	PF00136
Domain	DNA-dir_DNA_pol_B	POLA1 POLE	4.33e-04	4	160	2	IPR006172
Domain	DNA-dir_DNA_pol_B_exonuc	POLA1 POLE	4.33e-04	4	160	2	IPR006133
Domain	DNA-dir_DNA_pol_B_multi_dom	POLA1 POLE	4.33e-04	4	160	2	IPR006134
Domain	DNA_pol_B_exo1	POLA1 POLE	4.33e-04	4	160	2	PF03104
Domain	POLBc	POLA1 POLE	4.33e-04	4	160	2	SM00486
Domain	FN3_dom	EPHB3 EPHB4 TNC OBSL1 PTPRD TIE1 IGSF9B TNXB	4.49e-04	209	160	8	IPR003961
Domain	RasGAP_dom	IQGAP3 PLXNB1 RASAL1	4.58e-04	18	160	3	IPR001936
Domain	PROTEIN_KINASE_ATP	EPHB3 EPHB4 FLT4 LMTK3 STK31 PTK2 MAP3K4 TAOK2 TIE1 MYO3B MAST1 ROCK1	6.09e-04	459	160	12	PS00107
Domain	SET_dom	KMT2C EHMT2 PRDM13 SETD3	8.79e-04	50	160	4	IPR001214
Domain	SET	KMT2C EHMT2 PRDM13 SETD3	8.79e-04	50	160	4	PS50280
Domain	Tyr_kinase_cat_dom	EPHB3 EPHB4 FLT4 PTK2 TIE1	9.58e-04	88	160	5	IPR020635
Domain	TyrKc	EPHB3 EPHB4 FLT4 PTK2 TIE1	9.58e-04	88	160	5	SM00219
Domain	Spectrin	DRP2 SPTBN5 UTRN	9.63e-04	23	160	3	PF00435
Domain	ACTININ_2	SPTBN5 PLEC UTRN	9.63e-04	23	160	3	PS00020
Domain	ACTININ_1	SPTBN5 PLEC UTRN	9.63e-04	23	160	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 PLEC UTRN	9.63e-04	23	160	3	IPR001589
Domain	EF-hand_dom_typ1	DRP2 UTRN	1.07e-03	6	160	2	IPR015153
Domain	EF-hand_dom_typ2	DRP2 UTRN	1.07e-03	6	160	2	IPR015154
Domain	EF-hand_2	DRP2 UTRN	1.07e-03	6	160	2	PF09068
Domain	EF-hand_3	DRP2 UTRN	1.07e-03	6	160	2	PF09069
Domain	PROTEIN_KINASE_DOM	EPHB3 EPHB4 FLT4 LMTK3 STK31 PTK2 MAP3K4 TAOK2 TIE1 MYO3B MAST1 ROCK1	1.13e-03	493	160	12	PS50011
Domain	Ricin_B_lectin	GALNT11 MRC2 CRYBG1	1.24e-03	25	160	3	PF00652
Domain	Tyr_kinase_AS	EPHB3 EPHB4 FLT4 PTK2 TIE1	1.48e-03	97	160	5	IPR008266
Domain	APC_su10/DOC_dom	CUL9 CUL7	1.49e-03	7	160	2	IPR004939
Domain	tRNA_SAD	TARS3 AARS2	1.49e-03	7	160	2	IPR012947
Domain	DOC	CUL9 CUL7	1.49e-03	7	160	2	PS51284
Domain	ANAPC10	CUL9 CUL7	1.49e-03	7	160	2	PF03256
Domain	tRNA_SAD	TARS3 AARS2	1.49e-03	7	160	2	SM00863
Domain	APC10	CUL9 CUL7	1.49e-03	7	160	2	SM01337
Domain	tRNA_SAD	TARS3 AARS2	1.49e-03	7	160	2	PF07973
Domain	RICIN	GALNT11 MRC2 CRYBG1	1.73e-03	28	160	3	SM00458
Domain	RICIN_B_LECTIN	GALNT11 MRC2 CRYBG1	1.73e-03	28	160	3	PS50231
Domain	Ankyrin_rpt	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60 TCTN2	1.92e-03	262	160	8	IPR002110
Domain	Cullin_neddylation_domain	CUL9 CUL7	1.97e-03	8	160	2	IPR019559
Domain	Cullin_Nedd8	CUL9 CUL7	1.97e-03	8	160	2	PF10557
Domain	Cullin_Nedd8	CUL9 CUL7	1.97e-03	8	160	2	SM00884
Domain	Thr/Ala-tRNA-synth_IIc_edit	TARS3 AARS2	1.97e-03	8	160	2	IPR018163
Domain	Ricin_B_lectin	GALNT11 MRC2 CRYBG1	2.11e-03	30	160	3	IPR000772
Domain	CH	SPTBN5 PLEC UTRN IQGAP3	2.34e-03	65	160	4	SM00033
Domain	PH_dom-spectrin-type	SPTBN5 PSD4	2.52e-03	9	160	2	IPR001605
Domain	Cullin_homology	CUL9 CUL7	2.52e-03	9	160	2	IPR016158
Domain	Ank_2	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	2.57e-03	215	160	7	PF12796
Domain	RNaseH-like_dom	POLA1 ZNF862 POLE POLG	2.91e-03	69	160	4	IPR012337
Domain	CH	SPTBN5 PLEC UTRN IQGAP3	3.07e-03	70	160	4	PF00307
Domain	Cullin	CUL9 CUL7	3.14e-03	10	160	2	PF00888
Domain	CULLIN_2	CUL9 CUL7	3.14e-03	10	160	2	PS50069
Domain	Cullin_N	CUL9 CUL7	3.14e-03	10	160	2	IPR001373
Domain	CULLIN_1	CUL9 CUL7	3.14e-03	10	160	2	PS01256
Domain	-	SPTBN5 PLEC UTRN IQGAP3	3.23e-03	71	160	4	1.10.418.10
Domain	Prot_kinase_dom	EPHB3 EPHB4 FLT4 STK31 PTK2 MAP3K4 TAOK2 TIE1 MYO3B MAST1 ROCK1	3.33e-03	489	160	11	IPR000719
Domain	Ank	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	3.55e-03	228	160	7	PF00023
Domain	CH	SPTBN5 PLEC UTRN IQGAP3	3.57e-03	73	160	4	PS50021
Domain	Ephrin_rec_like	EPHB3 EPHB4	3.81e-03	11	160	2	PF07699
Domain	CH-domain	SPTBN5 PLEC UTRN IQGAP3	3.93e-03	75	160	4	IPR001715
Domain	EGF	TNC BCAN TIE1 LRP1 TNXB	4.61e-03	126	160	5	PF00008
Domain	Pkinase_Tyr	EPHB3 EPHB4 FLT4 PTK2 TIE1	5.09e-03	129	160	5	PF07714
Domain	SET	KMT2C EHMT2 SETD3	5.18e-03	41	160	3	PF00856
Domain	-	MRC2 MMP9	5.35e-03	13	160	2	2.10.10.10
Domain	Protein_kinase_ATP_BS	EPHB3 EPHB4 FLT4 PTK2 MAP3K4 TAOK2 TIE1 MYO3B ROCK1	5.46e-03	379	160	9	IPR017441
Domain	-	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	5.60e-03	248	160	7	1.25.40.20
Domain	Ig_I-set	FLT4 OBSL1 KIRREL2 PTPRD IGFBP7 IGSF9B	5.97e-03	190	160	6	IPR013098
Domain	I-set	FLT4 OBSL1 KIRREL2 PTPRD IGFBP7 IGSF9B	5.97e-03	190	160	6	PF07679
Domain	ANK	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	5.97e-03	251	160	7	SM00248
Domain	RECEPTOR_TYR_KIN_V_2	EPHB3 EPHB4	6.20e-03	14	160	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB3 EPHB4	6.20e-03	14	160	2	PS00790
Domain	RasGAP	IQGAP3 RASAL1	6.20e-03	14	160	2	SM00323
Domain	FN_type2_col-bd	MRC2 MMP9	6.20e-03	14	160	2	IPR000562
Domain	FN2_2	MRC2 MMP9	6.20e-03	14	160	2	PS51092
Domain	Tyr_kinase_rcpt_V_CS	EPHB3 EPHB4	6.20e-03	14	160	2	IPR001426
Domain	EphA2_TM	EPHB3 EPHB4	6.20e-03	14	160	2	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB3 EPHB4	6.20e-03	14	160	2	IPR001090
Domain	FN2_1	MRC2 MMP9	6.20e-03	14	160	2	PS00023
Domain	Eph_TM	EPHB3 EPHB4	6.20e-03	14	160	2	IPR027936
Domain	EPH_lbd	EPHB3 EPHB4	6.20e-03	14	160	2	SM00615
Domain	Ephrin_lbd	EPHB3 EPHB4	6.20e-03	14	160	2	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHB3 EPHB4	6.20e-03	14	160	2	IPR016257
Domain	fn2	MRC2 MMP9	6.20e-03	14	160	2	PF00040
Domain	EPH_LBD	EPHB3 EPHB4	6.20e-03	14	160	2	PS51550
Domain	FN2	MRC2 MMP9	6.20e-03	14	160	2	SM00059
Domain	RasGAP_CS	IQGAP3 RASAL1	6.20e-03	14	160	2	IPR023152
Domain	ANK_REPEAT	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	6.23e-03	253	160	7	PS50088
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	ARHGEF12 ROCK1 PLXNB1	7.49e-05	11	111	3	MM15046
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	EPHB3 EPHB4 PTK2 ROCK1 MMP9	1.57e-04	65	111	5	MM14911
Pathway	REACTOME_EPHB_MEDIATED_FORWARD_SIGNALING	EPHB3 EPHB4 PTK2 ROCK1	1.97e-04	37	111	4	MM15022
Pathway	WP_NEOVASCULARIZATION_PROCESSES	EPHB4 FLT4 NFKB2 MMP9	1.97e-04	37	111	4	M39506
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	ARHGEF12 ROCK1 PLXNB1	2.02e-04	15	111	3	MM15037
Pathway	PID_EPHB_FWD_PATHWAY	EPHB3 EPHB4 PTK2 ROCK1	2.67e-04	40	111	4	M62
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPHB4 ESYT1 POLE TMEM158 POLG LAD1 ADGRB2 CUL9 FRMD8 DYSF ABCA7 SYNE4 SH3BP4 C2CD2L TAOK2 SNX30 KMT2C WIZ NFKB2 RRP12 PLEC IQGAP3 PRRT4 TEX19 RASAL1 AHNAK2	3.05e-11	1105	169	26	35748872
Pubmed	A physical map of the genomic region on mouse chromosome 3 containing the hindshaker (hsh) mutation.	NES SELENBP1 BCAN IQGAP3	1.97e-06	19	169	4	14706451
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	ZNF862 RGL3 KIRREL2 LMTK3 PARP10 KMT2C AARS2 STARD9 MAST1	2.30e-06	233	169	9	37704626
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 CUL7 TRIP12 TAOK2 AARS2 RRP12 SNRNP200	3.61e-06	130	169	7	12421765
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	POGK DNAJC16 OBSL1 ARHGEF12 CUL9 MAP3K4 EPG5 C2CD2L STARD9 RRP12 MAST1	5.45e-06	407	169	11	12693553
Pubmed	Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion.	EPHB3 PTK2 MMP9	9.27e-06	9	169	3	18713744
Pubmed	Extra-embryonic vasculature development is regulated by the transcription factor HAND1.	EPHB3 EPHB4 FLT4 TIE1	1.01e-05	28	169	4	15073150
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ESYT1 POLE COQ5 POLG OBSL1 CUL7 C2CD2L SPTBN5 GK VIPAS39 WIZ AARS2 EHMT2 ALDH1L2 RRP12 PEX5 DNAJC1 ATP2A2 SPRYD4 MOV10 AHNAK2	1.32e-05	1496	169	21	32877691
Pubmed	Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development.	EPHB4 FLT4 TIE1	1.32e-05	10	169	3	10323857
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NES POLA1 POLE CUL9 CUL7 TRIP12 TSR1 RRP12 PLEC ATP2A2 UTRN SNRNP200 MOV10	2.03e-05	653	169	13	22586326
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NES PRR36 ADGRB2 ARHGEF12 LMTK3 TMEM132B PTK2 FBXO2 TAOK2 PTPRD WIZ EHMT2 LRP1 PEX5 ROCK1 RASAL1	2.07e-05	963	169	16	28671696
Pubmed	Tenascin-C modulates matrix contraction via focal adhesion kinase- and Rho-mediated signaling pathways.	TNC PTK2	2.35e-05	2	169	2	12388760
Pubmed	Overexpression of membrane sialic acid-specific sialidase Neu3 inhibits matrix metalloproteinase-9 expression in vascular smooth muscle cells.	NEU3 MMP9	2.35e-05	2	169	2	17382908
Pubmed	Natural history of facial and skeletal features from neonatal period to adulthood in a 3M syndrome cohort with biallelic CUL7 or OBSL1 variants.	OBSL1 CUL7	2.35e-05	2	169	2	34597859
Pubmed	The tenascin gene family in axon growth and guidance.	TNC TNXB	2.35e-05	2	169	2	9321695
Pubmed	Visualizing late states of human 40S ribosomal subunit maturation.	TSR1 RRP12	2.35e-05	2	169	2	29875412
Pubmed	Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family.	EPHB3 EPHB4	2.35e-05	2	169	2	7478528
Pubmed	Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.	LRP1 MMP9	2.35e-05	2	169	2	27931798
Pubmed	The co-expression of MMP-9 and Tenascin-C is significantly associated with the progression and prognosis of pancreatic cancer.	TNC MMP9	2.35e-05	2	169	2	26652622
Pubmed	Activation of the ROCK1/MMP-9 pathway is associated with the invasion and poor prognosis in papillary thyroid carcinoma.	ROCK1 MMP9	2.35e-05	2	169	2	28848996
Pubmed	Further expanding the mutational spectrum and investigation of genotype-phenotype correlation in 3M syndrome.	OBSL1 CUL7	2.35e-05	2	169	2	30980518
Pubmed	Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.	NES LRP1	2.35e-05	2	169	2	27258849
Pubmed	Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells.	PTK2 MMP9	2.35e-05	2	169	2	24675423
Pubmed	Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.	TNC TNXB	2.35e-05	2	169	2	17202312
Pubmed	Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells.	FLT4 PTK2	2.35e-05	2	169	2	16452200
Pubmed	ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.	RAG1 ABCA7	2.35e-05	2	169	2	28091533
Pubmed	NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens.	RAG1 NFKB2	2.35e-05	2	169	2	24242887
Pubmed	Distribution of tenascin-C and -X, and soft X-ray analysis of the mandibular symphysis during mandible formation in the human fetus.	TNC TNXB	2.35e-05	2	169	2	15455729
Pubmed	Tenascin variants: ligands and expression.	TNC TNXB	2.35e-05	2	169	2	7509489
Pubmed	The effects of tenascin C knockdown on trabecular meshwork outflow resistance.	TNC TNXB	2.35e-05	2	169	2	23882691
Pubmed	Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.	LRP1 MMP9	2.35e-05	2	169	2	12960961
Pubmed	Immunoexpression of ROCK-1 and MMP-9 as prognostic markers in breast cancer.	ROCK1 MMP9	2.35e-05	2	169	2	25218053
Pubmed	The extracellular matrix glycoprotein tenascin-C and matrix metalloproteinases modify cerebellar structural plasticity by exposure to an enriched environment.	TNC MMP9	2.35e-05	2	169	2	27089885
Pubmed	H3K27me1 is essential for MMP-9-dependent H3N-terminal tail proteolysis during osteoclastogenesis.	EHMT2 MMP9	2.35e-05	2	169	2	29807539
Pubmed	Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts.	TNC TNXB	2.35e-05	2	169	2	8856503
Pubmed	Association between focal adhesion kinase and matrix metalloproteinase-9 expression in prostate adenocarcinoma and their influence on the progression of prostatic adenocarcinoma.	PTK2 MMP9	2.35e-05	2	169	2	32106037
Pubmed	Tenascin-C upregulates matrix metalloproteinase-9 in breast cancer cells: direct and synergistic effects with transforming growth factor beta1.	TNC MMP9	2.35e-05	2	169	2	12672030
Pubmed	Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins.	NES PTK2	2.35e-05	2	169	2	24610946
Pubmed	Relevance of tenascin-C and matrix metalloproteinases in vascular abnormalities in murine hypoplastic lungs.	TNC MMP9	2.35e-05	2	169	2	16699260
Pubmed	Invasion of melanoma in double knockout mice lacking tenascin-X and tenascin-C.	TNC TNXB	2.35e-05	2	169	2	12359049
Pubmed	Plexin B1 inhibits integrin-dependent pp125FAK and Rho activity in melanoma.	PTK2 PLXNB1	2.35e-05	2	169	2	21029396
Pubmed	Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling.	PTK2 MMP9	2.35e-05	2	169	2	24284889
Pubmed	Inverse relationship between raft LRP1 localization and non-raft ERK1,2/MMP9 activation in idiopathic dilated cardiomyopathy: potential impact in ventricular remodeling.	LRP1 MMP9	2.35e-05	2	169	2	25131918
Pubmed	The change in tenascin expression in mouse uterus during early pregnancy.	TNC TNXB	2.35e-05	2	169	2	9013311
Pubmed	Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes.	LRP1 ATP2A2	2.35e-05	2	169	2	25968337
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MAP1A ESYT1 OBSL1 CUL9 CUL7 SH3BP4 SPTBN5 RRP12 PLEC MMP9 TEX19	3.40e-05	496	169	11	31343991
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MAP1A POGK POLA1 POLE TRIP12 MAP3K4 THOC6 ARL2 AARS2 EHMT2 SNRNP200 IQGAP3 MOV10	4.39e-05	704	169	13	29955894
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHB3 EPHB4 FLT4 TIE1	5.21e-05	42	169	4	11439183
Pubmed	The protein tyrosine kinase family of the human genome.	EPHB3 EPHB4 FLT4 PTK2 TIE1	5.46e-05	83	169	5	11114734
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	POLG OBSL1 CUL9 TRIP12 PTK2 TARS3 SNRNP48 PTPRD WIZ EHMT2 LRP1 MAST1 PLEC WDR17 ATP2A2 UTRN SNRNP200 DKK3	5.84e-05	1285	169	18	35914814
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	TRIP12 RRP12 CRYBG1 PLEC ATP2A2 SNRNP200 IQGAP3	6.26e-05	202	169	7	33005030
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	POLA1 ARHGAP9 TRIP12 TMEM132B NUDT12 KMT2C WIZ GALNT11 MYO3B PRDM13 IGSF9B UTRN SNRNP200	6.88e-05	736	169	13	29676528
Pubmed	Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway.	PTK2 ROCK1	7.02e-05	3	169	2	25011614
Pubmed	Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.	PTK2 MMP9	7.02e-05	3	169	2	26397194
Pubmed	Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity.	NFKB2 MMP9	7.02e-05	3	169	2	26732239
Pubmed	Tenascin-cmediated vasculogenic mimicry formation via regulation of MMP2/MMP9 in glioma.	TNC MMP9	7.02e-05	3	169	2	31754182
Pubmed	Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.	TNC TNXB	7.02e-05	3	169	2	7694605
Pubmed	Clearance of matrix metalloproteinase-9 is dependent on low-density lipoprotein receptor-related protein-1 expression downregulated by microRNA-205 in human abdominal aortic aneurysm.	LRP1 MMP9	7.02e-05	3	169	2	26781079
Pubmed	Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.	ARHGEF12 PLXNB1	7.02e-05	3	169	2	12220504
Pubmed	Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.	CUL9 CUL7	7.02e-05	3	169	2	15964813
Pubmed	FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.	FRMD8 FRMD8P1	7.02e-05	3	169	2	37527040
Pubmed	Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression.	NES MMP9	7.02e-05	3	169	2	19473053
Pubmed	Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.	POLA1 POLE	7.02e-05	3	169	2	22887995
Pubmed	FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.	PTK2 MMP9	7.02e-05	3	169	2	19150878
Pubmed	Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase.	ARHGEF12 PTK2	7.02e-05	3	169	2	11799111
Pubmed	A rare cause of syndromic short stature: 3M syndrome in three families.	OBSL1 CUL7	7.02e-05	3	169	2	33258289
Pubmed	The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism.	LRP1 MMP9	7.02e-05	3	169	2	11279011
Pubmed	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.	CUL9 CUL7	7.02e-05	3	169	2	17298945
Pubmed	The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.	ARHGEF12 PLXNB1	7.02e-05	3	169	2	12196628
Pubmed	[Effects of focal adhesional kinase signaling on TNF-α induced gelatinases activity in cornea epithelium].	PTK2 MMP9	7.02e-05	3	169	2	22336124
Pubmed	Lunasin suppresses the migration and invasion of breast cancer cells by inhibiting matrix metalloproteinase-2/-9 via the FAK/Akt/ERK and NF-κB signaling pathways.	PTK2 MMP9	7.02e-05	3	169	2	27175819
Pubmed	The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse.	TNC TNXB	7.02e-05	3	169	2	12823230
Pubmed	Epidermal growth factor stimulates matrix metalloproteinase-9 expression and invasion in human follicular thyroid carcinoma cells through Focal adhesion kinase.	PTK2 MMP9	7.02e-05	3	169	2	17397984
Pubmed	Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain.	LRP1 MMP9	7.02e-05	3	169	2	19672275
Pubmed	Three M Syndrome	OBSL1 CUL7	7.02e-05	3	169	2	20301654
Pubmed	Neurocan is dispensable for brain development.	TNC BCAN	7.02e-05	3	169	2	11486035
Pubmed	A novel p53-binding domain in CUL7.	CUL9 CUL7	7.02e-05	3	169	2	16875676
Pubmed	HIV gp120 binds to mannose receptor on vaginal epithelial cells and induces production of matrix metalloproteinases.	MRC2 MMP9	7.02e-05	3	169	2	22132194
Pubmed	Brevican, neurocan, tenascin-C and versican are mainly responsible for the invasiveness of low-grade astrocytoma.	TNC BCAN	7.02e-05	3	169	2	21997179
Pubmed	G9a Promotes Invasion and Metastasis of Non-Small Cell Lung Cancer through Enhancing Focal Adhesion Kinase Activation via NF-κB Signaling Pathway.	PTK2 EHMT2	7.02e-05	3	169	2	33298547
Pubmed	Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction.	LRP1 MMP9	7.02e-05	3	169	2	28378397
Pubmed	The function of DNA polymerases in DNA repair synthesis of ultraviolet-irradiated human fibroblasts.	POLA1 POLE	7.02e-05	3	169	2	1730053
Pubmed	Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.	LRP1 MMP9	7.02e-05	3	169	2	19176371
Pubmed	The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.	FRMD8 FRMD8P1	7.02e-05	3	169	2	36720499
Pubmed	DNA-Mediated Gene Therapy in a Mouse Model of Limb Girdle Muscular Dystrophy 2B.	RAG1 DYSF	7.02e-05	3	169	2	29159199
Pubmed	Low Expression of EphB2, EphB3, and EphB4 in Bladder Cancer: Novel Potential Indicators of Muscular Invasion.	EPHB3 EPHB4	7.02e-05	3	169	2	34296545
Pubmed	Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.	EEF1AKMT4-ECE2 EEF1AKMT4	7.02e-05	3	169	2	28520920
Pubmed	Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells.	TNC PTK2	7.02e-05	3	169	2	21281808
Pubmed	Expression of tenascin in developing and adult mouse lymphoid organs.	TNC TNXB	7.02e-05	3	169	2	7687262
Pubmed	The tenascin gene family.	TNC TNXB	7.02e-05	3	169	2	7530141
Pubmed	Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells.	TNC MMP9	7.02e-05	3	169	2	27717868
Pubmed	Cell-autonomous role for NF-kappa B in immature bone marrow B cells.	RAG1 NFKB2	7.02e-05	3	169	2	19265118
Pubmed	Distinctive activities of DNA polymerases during human DNA replication.	POLA1 POLE	7.02e-05	3	169	2	16762037
Pubmed	The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube.	KIRREL2 PRDM13	7.02e-05	3	169	2	24370451
Pubmed	Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.	CUL9 CUL7	7.02e-05	3	169	2	17229476
Pubmed	Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion.	MMP9 TNXB	7.02e-05	3	169	2	12419962
Pubmed	Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.	PTPRD ROCK1	7.02e-05	3	169	2	25703008
Pubmed	Tubular network formation by adriamycin-resistant MCF-7 breast cancer cells is closely linked to MMP-9 and VEGFR-2/VEGFR-3 over-expressions.	FLT4 MMP9	7.02e-05	3	169	2	22542663
Pubmed	The genetics of 3-M syndrome: unravelling a potential new regulatory growth pathway.	OBSL1 CUL7	7.02e-05	3	169	2	22156540
Pubmed	Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.	RAG1 LRP1	7.02e-05	3	169	2	24778318
GeneFamily	Fibronectin type III domain containing	EPHB3 EPHB4 TNC PTPRD TIE1 IGSF9B TNXB	6.94e-05	160	114	7	555
GeneFamily	DNA polymerases	POLA1 POLE POLG	3.94e-04	23	114	3	535
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT4 OBSL1 KIRREL2 PTPRD IGFBP7 IGSF9B	5.49e-04	161	114	6	593
GeneFamily	Ankyrin repeat domain containing	SOWAHD ANKRD26 NUDT12 EHMT2 USH1G NFKB2 ANKRD60	8.62e-04	242	114	7	403
GeneFamily	Cullins	CUL9 CUL7	1.08e-03	8	114	2	1032
GeneFamily	Immunoglobulin like domain containing	FLT4 OSCAR OBSL1 KIRREL2 TIE1 IGSF9B	1.41e-03	193	114	6	594
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT4 LMTK3 TIE1	2.04e-03	40	114	3	321
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB3 EPHB4	3.41e-03	14	114	2	1095
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	NES TNC ADGRB2 OBSL1 PARD3B BCAN C8orf34 HEPN1 NPTXR MRC2 LRP1 PRDM13 IGSF9B	5.53e-06	439	168	13	M39054
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	SELENBP1 TNC DHDDS C8orf34 IGFBP7 MRC2 LBH UTRN DKK3	6.72e-08	197	169	9	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TNC DHDDS PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	7.65e-08	200	169	9	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NES DYSF IGFBP7 TIE1 TREH TNXB PRRT4 ACSM2B	2.80e-07	169	169	8	0d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	PCSK2 GPR20 TNC RGL3 IGFBP7 LBH ROCK1 UTRN	3.06e-07	171	169	8	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 FLT4 DYSF TIE1 EXOC3L1 KLHL14 C6orf141 TNXB	6.29e-07	188	169	8	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 FLT4 DYSF TIE1 EXOC3L1 KLHL14 C6orf141 TNXB	6.29e-07	188	169	8	1f40b959777d18ad88d239df8cca304f062ba04c
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	EPHB4 FLT4 IGFBP7 TIE1 KLHL14 C6orf141 DKK3 ACSM2B	6.82e-07	190	169	8	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 KLHL14 C6orf141 TNXB	6.82e-07	190	169	8	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	7.67e-07	193	169	8	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	7.67e-07	193	169	8	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TNC DHDDS PTPRD IGFBP7 MRC2 LRP1 LBH DKK3	9.30e-07	198	169	8	0a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB4 FLT4 DYSF IGFBP7 TIE1 UTRN DKK3 ACSM2B	9.30e-07	198	169	8	99d6a64f3410dae3019161feef20a8f06081a24b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 ADAMTS17 LRP1 LBH TNXB DKK3	9.66e-07	199	169	8	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	1.00e-06	200	169	8	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	1.00e-06	200	169	8	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 EXOC3L1 KLHL14 C6orf141 ACSM2B	1.00e-06	200	169	8	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 EXOC3L1 KLHL14 C6orf141 ACSM2B	1.00e-06	200	169	8	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	1.00e-06	200	169	8	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB DKK3	1.00e-06	200	169	8	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Cadm1_(Cerebellum_basket_cells_3)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	POLE OSCAR ADAMTS17 TSKS SPEM1	1.44e-06	51	169	5	0611419cc63dbe772d10c1f6f96826786351f048
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Cadm1_(Cerebellum_basket_cells_3)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	POLE OSCAR ADAMTS17 TSKS SPEM1	1.44e-06	51	169	5	a673b6d6ddecb7c239cb49ff490188460edc87e0
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PCSK2 GPR20 TNC IGFBP7 LBH ROCK1 UTRN	3.29e-06	165	169	7	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	EPHB4 FLT4 IGFBP7 C6orf141 TNXB DKK3 ACSM2B	4.49e-06	173	169	7	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	REC8 RGL3 SYNE4 FBXO2 USH1G MESP2 RASAL1	5.42e-06	178	169	7	3d120458a0a56097532ebfa5fc6f77b52af2af2a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 UTRN TNXB	5.42e-06	178	169	7	ad3de3e03a401dac64431a541899445262246347
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TNC TMEM158 IGFBP7 MRC2 LRP1 LBH DKK3	5.83e-06	180	169	7	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB4 FLT4 STK31 TMEM132B TIE1 EXOC3L1 TNXB	5.83e-06	180	169	7	25f8e82bbc1853cb7d072484e99369c72779dd1e
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 FLT4 DYSF TIE1 EXOC3L1 C6orf141 ACSM2B	6.04e-06	181	169	7	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 FLT4 DYSF TIE1 EXOC3L1 C6orf141 ACSM2B	6.04e-06	181	169	7	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 FLT4 IGFBP7 TIE1 USH1G EXOC3L1 DKK3	6.27e-06	182	169	7	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM158 NCCRP1 CORO1A TREH NFKB2 MAST1 PLEC	6.27e-06	182	169	7	b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 FLT4 IGFBP7 TIE1 USH1G EXOC3L1 DKK3	6.27e-06	182	169	7	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 UTRN TNXB	6.50e-06	183	169	7	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 C6orf141 TNXB DKK3 ACSM2B	6.73e-06	184	169	7	0087c605c161fd8a39aa394f51994a04e8353bf1
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHB4 FLT4 DYSF IGFBP7 TIE1 EXOC3L1 TNXB	6.73e-06	184	169	7	1a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 C6orf141 TNXB DKK3 ACSM2B	6.73e-06	184	169	7	968afa6b5ba84169377a24c150bb68749fa674d9
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 C6orf141 TNXB DKK3 ACSM2B	6.73e-06	184	169	7	15cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell	3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 C6orf141 TNXB DKK3 ACSM2B	6.73e-06	184	169	7	920f95625978132c2b6c76654ef6298244103e2d
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 KLHL14 C6orf141	7.22e-06	186	169	7	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	Thalamus-Endothelial\|Thalamus / BrainAtlas - Mouse McCarroll V32	EPHB4 NES ESYT1 DYSF IGFBP7 UTRN CCDC102A	7.22e-06	186	169	7	dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 UTRN TNXB	7.22e-06	186	169	7	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 UTRN TNXB	7.22e-06	186	169	7	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 KLHL14 C6orf141	7.22e-06	186	169	7	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 GK PTPRD IGFBP7 GALNT11 ATP2A2 ACSM2B	7.48e-06	187	169	7	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 PTPRD IGFBP7 TMEM178A MRC2 TNXB DKK3	7.48e-06	187	169	7	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 POLA1 DYSF SPTBN5 TIE1 STARD9 TNXB	7.48e-06	187	169	7	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 C6orf141 ACSM2B	7.48e-06	187	169	7	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	OSCAR DYSF TIE1 GPR150 EXOC3L1 TSKS	7.59e-06	123	169	6	e0130010aa406d4e9d8f16ad32858c382277eeb2
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	FLT4 DYSF IGFBP7 TIE1 KLHL14 C6orf141 TNXB	7.75e-06	188	169	7	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 DYSF IGFBP7 TIE1 KLHL14 C6orf141 TNXB	7.75e-06	188	169	7	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPHB4 FLT4 DYSF IGFBP7 KLHL14 C6orf141 TNXB	7.75e-06	188	169	7	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.02e-06	189	169	7	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.02e-06	189	169	7	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.02e-06	189	169	7	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 LBH DKK3	8.02e-06	189	169	7	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	wk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 KLHL14 C6orf141	8.30e-06	190	169	7	279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAD1 BCAN TMEM132B SH3BP4 LRP1 IGSF9B CSMD1	8.30e-06	190	169	7	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.30e-06	190	169	7	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	wk_08-11-Endothelial-Lymph_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLT4 DYSF IGFBP7 TIE1 EXOC3L1 KLHL14 C6orf141	8.30e-06	190	169	7	d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAD1 BCAN TMEM132B SH3BP4 LRP1 IGSF9B CSMD1	8.30e-06	190	169	7	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 FLT4 DYSF TIE1 STARD9 C6orf141 TNXB	8.59e-06	191	169	7	f663131a4810584c5854bd64ee7991a237b7707f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.59e-06	191	169	7	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 SELENBP1 PTPRD IGFBP7 MRC2 TNXB DKK3	8.59e-06	191	169	7	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 LBH DKK3	8.59e-06	191	169	7	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 LBH DKK3	8.59e-06	191	169	7	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELENBP1 PTPRD IGFBP7 MRC2 LRP1 TNXB DKK3	8.59e-06	191	169	7	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TNC IGFBP7 MRC2 ADAMTS17 LRP1 LBH DKK3	8.89e-06	192	169	7	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELENBP1 TNC PTPRD MRC2 ADAMTS17 LRP1 LBH	9.19e-06	193	169	7	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELENBP1 TNC PTPRD MRC2 ADAMTS17 LRP1 LBH	9.19e-06	193	169	7	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SELENBP1 TNC PTPRD ADAMTS17 LRP1 LBH DKK3	9.51e-06	194	169	7	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)\|Striatum / BrainAtlas - Mouse McCarroll V32	KIRREL2 FANCF IGSF9B FBXO27 PRRT4 AHNAK2	9.54e-06	128	169	6	7e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Striatum / BrainAtlas - Mouse McCarroll V32	KIRREL2 FANCF IGSF9B FBXO27 PRRT4 AHNAK2	9.54e-06	128	169	6	a876303c852db2af9418d1a1711d7c950805018a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-\|Striatum / BrainAtlas - Mouse McCarroll V32	KIRREL2 FANCF IGSF9B FBXO27 PRRT4 AHNAK2	9.54e-06	128	169	6	388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCell	distal-Endothelial-Lymphatic\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 DKK3 ACSM2B	1.02e-05	196	169	7	3e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCell	390C-Endothelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 NES FLT4 DYSF IGFBP7 TIE1 EXOC3L1	1.05e-05	197	169	7	aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell	distal-3-Endothelial-Lymphatic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 IGFBP7 TIE1 KLHL14 C6orf141 DKK3 ACSM2B	1.05e-05	197	169	7	9ea0e2ed9c3f97591a06e70570640996580417d5
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB4 FLT4 DYSF IGFBP7 TIE1 UTRN DKK3	1.09e-05	198	169	7	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	TNC PARD3B BCAN TMEM132B HEPN1 MRC2 DNAJC1	1.09e-05	198	169	7	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLT4 DYSF TIE1 EXOC3L1 KLHL14 DKK3 ACSM2B	1.09e-05	198	169	7	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT4 DYSF IGFBP7 TIE1 KLHL14 C6orf141 ACSM2B	1.09e-05	198	169	7	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Bronchus_Control_(B.)-Endothelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	PCSK2 ARHGEF12 SPTBN5 FAM83G TSKS C6orf141 DKK3	1.09e-05	198	169	7	feac39036b5c0ab97b524cc366286942d136d42f
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLT4 DYSF TIE1 EXOC3L1 KLHL14 DKK3 ACSM2B	1.09e-05	198	169	7	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT4 DYSF IGFBP7 TIE1 KLHL14 C6orf141 ACSM2B	1.09e-05	198	169	7	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 C6orf141 TNXB DKK3	1.12e-05	199	169	7	a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 NES FLT4 DYSF TIE1 EXOC3L1 TNXB	1.12e-05	199	169	7	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 LRP1 LBH TNXB DKK3	1.12e-05	199	169	7	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 LRP1 LBH TNXB DKK3	1.12e-05	199	169	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB	1.12e-05	199	169	7	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TNC DHDDS IGFBP7 MRC2 LRP1 LBH TNXB	1.12e-05	199	169	7	38ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 C6orf141 TNXB DKK3	1.12e-05	199	169	7	1587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	NES TNC OBSL1 BCAN HEPN1 MRC2 DNAJC1	1.12e-05	199	169	7	0fee11bd72b27202f8d9fa4daba831ea9c8a61b2
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TNC PTPRD IGFBP7 MRC2 LRP1 LBH TNXB	1.16e-05	200	169	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	TNC DHDDS IGFBP7 MRC2 LRP1 LBH DKK3	1.16e-05	200	169	7	ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 LRP1 LBH TNXB DKK3	1.16e-05	200	169	7	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Parenchymal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 NES FLT4 DYSF IGFBP7 TIE1 TNXB	1.16e-05	200	169	7	0e648e9eb96c83a94505d07323785a7a40997eb0
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 C6orf141 TNXB DKK3	1.16e-05	200	169	7	e50ef394e3284a8323bfd60575b262b2be422aea
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 FLT4 DYSF TIE1 C6orf141 TNXB DKK3	1.16e-05	200	169	7	c59f262b2b0a7e7dcb2940d1e466f98db6c56625
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SELENBP1 MAP1A TNC LRP1 IGSF9B TNXB DKK3	1.16e-05	200	169	7	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 LRP1 LBH TNXB DKK3	1.16e-05	200	169	7	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TNC PTPRD MRC2 LRP1 LBH TNXB DKK3	1.16e-05	200	169	7	bd8cf33502adea320e91ca2af14e1911d88ad374
Disease	X-12063 measurement	EPHB4 GPR20 ADGRB2 ANKRD26 STK31 EPG5 TUBGCP3	8.54e-05	186	164	7	EFO_0021283
Disease	3-M syndrome	OBSL1 CUL7	9.18e-05	3	164	2	cv:C1848862
Disease	3-M syndrome (is_implicated_in)	OBSL1 CUL7	9.18e-05	3	164	2	DOID:0060241 (is_implicated_in)
Disease	muscular dystrophy (implicated_via_orthology)	DYSF POPDC3 UTRN	2.08e-04	21	164	3	DOID:9884 (implicated_via_orthology)
Disease	Metastatic melanoma	EPHB4 FLT4 PTK2 MAST1	2.34e-04	54	164	4	C0278883
Disease	triacylglycerol 58:9 measurement	NFKB2 CSMD1 TNXB	2.40e-04	22	164	3	EFO_0010443
Disease	response to mepolizumab	EPM2A UTRN	3.04e-04	5	164	2	EFO_0008459
Disease	melanoma	REC8 TNC TMEM132B ARL2 CRYBG1 DNAJC1 KDM4B	4.95e-04	248	164	7	C0025202
Disease	pulmonary hypertension (is_implicated_in)	PTK2 MMP9 ATP2A2	6.13e-04	30	164	3	DOID:6432 (is_implicated_in)
Disease	nephrotic syndrome	COCH PTPRD RRP12 TNXB	6.69e-04	71	164	4	EFO_0004255
Disease	coronary aneurysm	MYO3B MESP2 CSMD1	9.68e-04	35	164	3	EFO_1000881
Disease	pulse pressure measurement, migraine without aura, susceptibility to, 4	LRP1 SPOP	1.08e-03	9	164	2	EFO_0005763, MONDO_0011847
Disease	Nonsyndromic Deafness	TNC SYNE4 COCH USH1G	1.10e-03	81	164	4	C3711374
Disease	lysine measurement	REC8 PCSK2 SPRYD4	1.14e-03	37	164	3	EFO_0005002
Disease	tenascin measurement	TNC TNXB	1.34e-03	10	164	2	EFO_0008296
Disease	alopecia areata (is_marker_for)	EHMT2 KDM4B	1.34e-03	10	164	2	DOID:986 (is_marker_for)
Disease	pleural tuberculosis (is_marker_for)	TNC MMP9	1.34e-03	10	164	2	DOID:106 (is_marker_for)
Disease	Neurodevelopmental Disorders	PARD3B TRIP12 KMT2C PLXNB1	1.83e-03	93	164	4	C1535926
Disease	mean arterial pressure	RGL3 ARHGEF12 TRIP12 FANCF PTPRD CLCN6 ATP2A2 KDM4B MOV10	1.98e-03	499	164	9	EFO_0006340
Disease	cholangiocarcinoma (biomarker_via_orthology)	TNC MMP9	2.30e-03	13	164	2	DOID:4947 (biomarker_via_orthology)
Disease	ascorbic acid 2-sulfate measurement	TAOK2 CORO1A	2.30e-03	13	164	2	EFO_0800169
Disease	triacylglycerol 46:2 measurement	MYO3B CSMD1	2.67e-03	14	164	2	EFO_0010402
Disease	Alzheimer disease, visuospatial impairment	AARS2 CSMD1	2.67e-03	14	164	2	EFO_0009752, MONDO_0004975
Disease	Autosomal recessive limb-girdle muscular dystrophy	DYSF PLEC	2.67e-03	14	164	2	cv:C2931907
Disease	high grade glioma (biomarker_via_orthology)	TNC BCAN	3.07e-03	15	164	2	DOID:3070 (biomarker_via_orthology)
Disease	monoclonal gammopathy	TNC PTPRD CSMD1	3.22e-03	53	164	3	EFO_0000203
Disease	brain aneurysm	PCSK2 SLC2A14 PARD3B PTPRD	3.70e-03	113	164	4	EFO_0003870
Disease	antisaccade response measurement	PLEC CSMD1 RINL	3.77e-03	56	164	3	EFO_0006874
Disease	vital capacity	EPHB3 DHDDS STK31 TRIP12 C8orf34 GHSR PTPRD MRC2 ADAMTS17 ATP2A2 UTRN TNXB DKK3 KDM4B MOV10	3.86e-03	1236	164	15	EFO_0004312
Disease	sex interaction measurement, ulcerative colitis	EHMT2 TNXB	3.95e-03	17	164	2	EFO_0000729, EFO_0008343
Disease	lateral occipital cortex volume measurement	EPM2A UTRN	3.95e-03	17	164	2	EFO_0010311
Disease	cortical thickness change measurement	PARD3B CSMD1	4.43e-03	18	164	2	EFO_0021501
Disease	Malignant neoplasm of endometrium	POLE SPOP	4.43e-03	18	164	2	C0007103
Disease	Carcinoma in situ of endometrium	POLE SPOP	4.43e-03	18	164	2	C0346191
Disease	Omenn Syndrome	RAG1 CORO1A	4.93e-03	19	164	2	C2700553
Disease	pursuit maintenance gain measurement	EPG5 PTPRD C11orf21 CSMD1	5.00e-03	123	164	4	EFO_0008433
Disease	loneliness measurement	EPM2A PTPRD CSMD1 UTRN	5.15e-03	124	164	4	EFO_0007865
Disease	glaucoma (is_marker_for)	SELENBP1 MMP9	5.46e-03	20	164	2	DOID:1686 (is_marker_for)
Disease	Severe Combined Immunodeficiency	RAG1 CORO1A	5.46e-03	20	164	2	C0085110
Disease	brain age measurement	EEF1AKMT4-ECE2 EEF1AKMT4	5.46e-03	20	164	2	EFO_0010602

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSCGEELPWDELDLG	USH1G	366	Q495M9
DLTWLRPTEPGSEGD	ADGRB2	1336	O60241
QLREDTWAPLGGLEL	EXOC3L1	171	Q86VI1
FLDEWLTLEDVPSGR	ESYT1	746	Q9BSJ8
GGEEDEDPETSWILL	EPG5	556	Q9HCE0
DGPVDSDILLKEWSG	CSMD1	1336	Q96PZ7
VFWADDGLDTGPILL	ALDH1L2	156	Q3SY69
LDEELHGTFPGLWLA	GPR20	41	Q99678
GEWIGREENDADPLA	C8orf34	271	Q49A92
DGWTELVLAAVEGDP	ANKRD60	171	Q9BZ19
LTKGDPGSLEEWETV	EHMT2	251	Q96KQ7
DPALTAEEWLGGRDA	CORO1A	371	P31146
AEEWLGGRDAGPLLI	CORO1A	376	P31146
SALGLGQEEDIESPW	ANKRD26	406	Q9UPS8
AVAPARGWESGDLEL	DNAJC1	41	Q96KC8
LLLVWGLDPGTAVGD	ADAMTS17	16	Q8TE56
LPSGQELGRSVEELW	ABCA7	1426	Q8IZY2
ELGRSVEELWALLSP	ABCA7	1431	Q8IZY2
EDLLTWFSGPGEEKL	ARHGEF12	866	Q9NZN5
VPEIIERDGSIGAWA	RAG1	946	P15918
VTLGDWSDPLDPDAE	RASAL1	711	O95294
GEALGPEELRLTGWE	REC8	251	O95072
EDEAGPWILLSDDKG	RILP	316	Q96NA2
EGDLGTLQWTEGRIP	IQCC	41	Q4KMZ1
EEWEELLVEGLEGPE	PALM3	351	A6NDB9
TGENLLPGIDWLLDD	ARL2	161	P36404
GVEGRWSRDGEELPV	OBSL1	456	O75147
TIEGDFLWSDGVPLL	BCAN	751	Q96GW7
DDELWSLGKGVVVPT	MMP9	206	P14780
KGLLLPNDGWAESEV	PARD3B	641	Q8TEW8
EPGLWLGEVELAAEE	EPM2A	56	O95278
RGPWALEEESLVGRE	LAD1	151	O00515
DGDFEVPGLSIWTDL	FANCF	336	Q9NPI8
AGKLWDELSLVGLPD	KMT2C	221	Q8NEZ4
GLEVERWLAESPVGL	MAP1A	1766	P78559
LEWSAPLESGGREDL	EPHB4	341	P54760
EPILWLEFDGDSEGT	FRMD8	331	Q9BZ67
GWVLEPDGESCRSLD	LRP1	1251	Q07954
AIALDPRDGILFWTD	LRP1	1391	Q07954
DLGVGSPDWKNLLID	LINC02872	81	A2RU37
PELWQEDLEGARLGI	MESP2	381	Q0VG99
VEPTEGEVESGELRW	LBH	66	Q53QV2
EPILWLEFDRDSGVT	FRMD8P1	331	Q9BZ68
AEVLGERGTAPWVEE	LMTK3	626	Q96Q04
FEWEDELPRAEGLGT	BNIPL	141	Q7Z465
QLLLEEWGPLSGGLE	NCCRP1	71	Q6ZVX7
ILGDIFDEGKWSTPE	MPPE1	116	Q53F39
WRVEELPGDSGVEFT	FBXO2	146	Q9UK22
DTPGLWELEEATLGA	PLXNB1	896	O43157
QSEEKLWLGEPEGTA	PEX5	166	P50542
SPDEDGISPLGWLLD	CUL7	1056	Q14999
KWDLVPLSELGRAEG	GALNT11	301	Q8NCW6
DPWIGSESDKFILLG	DNAJC16	466	Q9Y2G8
PVDRTEGGWISLQDL	POLG	1011	P54098
LLLDPAAWDRDGESD	NES	1396	P48681
PPSEGELVELRWTDG	KDM4B	976	O94953
DSLEDCVTIWGPEGR	MRC2	476	Q9UBG0
ILEWSEPRDLGGRDD	EPHB3	356	P54753
LDVRLLEVSPGDTGW	TUBGCP3	621	Q96CW5
VDEGGGWLPQETLEL	MRGPRX3	301	Q96LB0
EQIGRPLELDTDGIW	POLE	851	Q07864
GWVLVSPLSKEDAGE	IGFBP7	231	Q16270
DVLWEIESELPGGGE	POGK	581	Q9P215
LAPLQDWGEETEDGA	RGL3	11	Q3MIN7
NAWEEFRGLLPVDGE	GARIN1B	31	Q96KD3
FGLELILGSEELWPV	SLC2A14	196	Q8TDB8
EPVDSGALWGLERPE	NEURL2	6	Q9BR09
DGPWDSPALILELED	NPTXR	181	O95502
PIDGIDAVLIATWLG	POLA1	1226	P09884
GDPGAVLWLEEIRQG	IQGAP3	581	Q86VI3
SDDILWPEGDEALPT	MAST1	601	Q9Y2H9
EVLVISWEGEGPEAR	OSCAR	211	Q8IYS5
EAEAWEEPTELLGLP	RBBP8NL	326	Q8NC74
GTLDALLAGERDPWT	EEF1AKMT4-ECE2	131	P0DPD8
WGSNELPAEEGKTLL	ATP2A2	36	P16615
ALVWEGGSDPLLELS	CEFIP	1116	Q711Q0
GLRGVPLLEWETEVE	CLCN6	581	P51797
KGTWTELEGDVAEPL	KLHL14	596	Q9P2G3
EEIPGEGLLISWAFT	C2CD2L	196	O14523
LGPRAGEELDRESWV	C6orf141	71	Q5SZD1
WDASPGNDSLGDELL	GHSR	21	Q92847
PALLADGDWESREEL	CCDC102A	61	Q96A19
EIIDWPGTEGRLAGQ	ZNHIT6	81	Q9NWK9
AAEGVGVWSLEPEDL	GK	471	P32189
LGIAPWVDGESELEF	HEPN1	6	Q6WQI6
EGLVWRDGEPVQGLT	MAN2C1	106	Q9NTJ4
AGLAWVLGDAEELPF	COQ5	191	Q5HYK3
PELLWFRDGVLLDGA	KIRREL2	156	Q6UWL6
PDAEGVSALGWLLDQ	CUL9	1386	Q8IWT3
SIPLEEGELELSGLW	CRYBG1	1076	Q9Y4K1
EGELELSGLWGIEDI	CRYBG1	1081	Q9Y4K1
EEGLWPELLDSGRIE	FBXO27	171	Q8NI29
GWPSDDIEEAGIVAR	COCH	276	O43405
WGVEQGLLDPSDISE	DHDDS	171	Q86SQ9
LVDESGGSPLEWIGL	PRDM13	56	Q9H4Q3
SRLLDLITWELEPDG	DKK3	246	Q9UBP4
EWDLKGIPLDQGSEL	DYSF	51	O75923
LDSPEWDSLRPTEEG	POPDC3	181	Q9HBV1
EGVRATWEPIGDLFI	DRP2	251	Q13474
TELRDALPGVDASLW	PANX2	101	Q96RD6
TLEGLDLDGEDWLPR	PARP10	601	Q53GL7
TDEEEGLIWVVGPVL	PTPRD	1261	P23468
LARDSSDIGWVLELP	FAM83G	516	A6ND36
RLESEDDSLGWGAPD	MAP3K4	496	Q9Y6R4
VNGELWDLDRPLEGD	TARS3	201	A2RTX5
WDLDRPLEGDSSLEL	TARS3	206	A2RTX5
GWKPVGDLLIDSLQD	UTRN	2716	P46939
KSPEGGEELVDFWIL	RGSL1	96	A5PLK6
LGSAVPVWLAEDDLG	RNF135	6	Q8IUD6
DTVLGLGDDTLLWPG	PNKD	276	Q8N490
WDGELLTHSGLEVPE	SPRYD4	191	Q8WW59
SPDEVAKELELLGGW	SH3BP4	131	Q9P0V3
ELELLPEWFSSGLDL	TMEM132B	186	Q14DG7
LPTSTELEWDPAGDI	SYNE4	241	Q8N205
EGEGGLSLQVEPEWR	MOV10	986	Q9HCE1
DPESWRSLLGLGGLD	TMEM178A	86	Q8NBL3
WIISVELAIGPEEGI	PTK2	266	Q05397
WEATLGPDRESLEGL	PNMA3	336	Q9UL41
ELGRWAELLSPLDES	PRR36	1301	Q9H6K5
AWELLGEPRAATGDL	GPR150	106	Q8NGU9
VGLIESPEGTEELKW	MED24	291	O75448
VLWELESEPDLGDGA	PSD4	296	Q8NDX1
WEEQLGREAGGTREP	PSD4	996	Q8NDX1
EDGSRVTLALIPLWD	SETD3	261	Q86TU7
LDEEFELGWVQGPAL	TAOK2	881	Q9UL54
LDGETFEVKGTWERP	SELENBP1	166	Q13228
EDGLVAWFALGIDPI	NUDT12	221	Q9BQG2
ELGEWDKALSIAPGV	WDR17	841	Q8IZU2
DLEDLEGLAQPSEWG	WIZ	191	O95785
AGRGSLEWLDLDGDL	STARD9	596	Q9P2P6
AGWLSEERAEELGGP	SOWAHD	86	A6NJG2
EELEDWDPGTSALPA	RHBDL1	11	O75783
GTLDALLAGERDPWT	EEF1AKMT4	131	P0DPD7
EERPLKTGIWSELGL	SPEM1	186	Q8N4L4
DPDLETRDIWLSLGV	AARS2	181	Q5JTZ9
DGSEETLDFPRSWLL	RRP12	556	Q5JTH9
EDSLASEGLWDPLAP	SPTBN5	2596	Q9NRC6
LEELGPWGDSLEETG	AHNAK2	356	Q8IVF2
AGGESLLPETLENWR	ACSM2B	336	Q68CK6
LAIRLGWDLDLEAGP	C11orf21	101	Q9P2W6
RLEEEAGTPSESWLL	NEU3	316	Q9UQ49
WREAEGDSGLLPLIF	STK31	781	Q9BXU1
DTQDAEALVGLWPLG	RINL	56	Q6ZS11
EPWLEEEEVLGSGRA	ZIM3	66	Q96PE6
ADGLRTGVTEWLEPL	ZWILCH	276	Q9H900
ILFLLDPLEGWDSTG	TSR1	156	Q2NL82
QRDGEGWEESISIPL	MKRN2OS	101	H3BPM6
TWSALEGELAEPLEG	SNX30	286	Q5VWJ9
RWELLDDGIPGTEGE	IGSF9B	656	Q9UPX0
GAGDPLWIDVDRPEE	TIE1	686	P35590
DFSLEELQGEPGWRL	TMEM158	201	Q8WZ71
VPECRLADELGGLWE	SPOP	181	O43791
EWLKGPILEATAGDE	FLT4	336	P35916
DSLLLRWTVPEGEFD	TNXB	1076	P22105
DLPQLGDLAVSEVGW	TNC	1346	P24821
LADTLPEGDREALWA	TREH	296	O43280
PEVLSGGEDGAVRLW	THOC6	181	Q86W42
GEEVASGLRTDPLWE	PRRT4	86	C9JH25
PGQEGRLDLDSTEWD	ARHGAP9	611	Q9BRR9
PWDPDDADITEILSG	TSKS	121	Q9UJT2
DDDLERVSWSGEPVG	VIPAS39	51	Q9H9C1
VDGAEWGVDLPSVEA	PLEC	676	Q15149
ETDGNLPESRIEGWL	ROCK1	1111	Q13464
PTGYSEEALLEEWLG	ZNF862	981	O60290
PEKGRWTELGALDIL	SNRNP200	836	O75643
SLKENLEDISGWGLP	ZNF74	21	Q16587
LEDISGWGLPEARSK	ZNF74	26	Q16587
LGPELWETVALALGV	TRMT12	156	Q53H54
DEDEEAATGPLGWRL	TOR3A	76	Q9H497
AEPRVSVLEGGEAWL	VSIG10L2	506	P0DP72
DLGLWRGEEVTLSNP	TRIP12	1646	Q14669
DGWLEIIRVDAPDPG	TCTN2	531	Q96GX1
LGWDLDSLDPGEEEA	SNRNP48	36	Q6IEG0
PLGLGLEDADWTQGL	TEX19	131	Q8NA77
GLESLPDPTDTWEII	MYO3B	16	Q8WXR4
TPGLDLNVAEAWELG	PCSK2	141	P16519
LLDGPEAQGSWAELA	NFKB2	781	Q00653