Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	POU2F1 MEF2A MEF2D CASZ1 TLX1 KMT2D USF3 MTF1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 ZNF292	5.43e-08	560	122	17	GO:0001228
GeneOntologyMolecularFunction	transcription coregulator activity	HDAC9 KDM3A NCOA6 ZMYND11 PPRC1 NACA WWTR1 CHD4 SRCAP ARID1B KMT2D YAP1 ELK1 KAT6B ZBED1 MED13 RBFOX2	5.71e-08	562	122	17	GO:0003712
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	POU2F1 MEF2A MEF2D CASZ1 TLX1 KMT2D USF3 MTF1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 ZNF292	6.33e-08	566	122	17	GO:0001216
GeneOntologyMolecularFunction	transcription factor binding	HDAC9 KDM3A NCOA6 PPRC1 PCLO NACA CHD4 MEF2A MEF2D LATS1 YAP1 ARID2 ELK1 PAX6 NFAT5 MED13 RBFOX2 TP73 RAD21	1.53e-07	753	122	19	GO:0008134
GeneOntologyMolecularFunction	transcription coactivator activity	NCOA6 PPRC1 NACA WWTR1 SRCAP ARID1B KMT2D YAP1 ELK1 KAT6B ZBED1 MED13	3.52e-07	303	122	12	GO:0003713
GeneOntologyMolecularFunction	chromatin binding	KDM3A NCOA6 POU2F1 CHD4 MEF2A ARID1B SBNO1 YAP1 SUPT6H MITF ELK1 PAX6 KAT6B CABIN1 NFAT5 NEUROG3 RAD21	2.59e-06	739	122	17	GO:0003682
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	HDAC9 KDM3A NCOA6 ZMYND11 PPRC1 NACA WWTR1 CHD4 SRCAP WNK1 ARID1B KMT2D GAS2L2 YAP1 PXN ELK1 KAT6B ZBED1 MED13 RBFOX2	2.37e-05	1160	122	20	GO:0030674
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX5 POU2F1 ZBTB41 MEF2A MEF2D CASZ1 TLX1 KMT2D USF3 ZFHX4 MTF1 MITF ZBTB40 ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 ZNF292 NPAS2	4.16e-05	1412	122	22	GO:0000981
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	HDAC9 KDM3A NCOA6 CHD4 MEF2A MEF2D LATS1 YAP1 ELK1 MED13 RBFOX2 TP73 RAD21	5.77e-05	582	122	13	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX5 POU2F1 ZBTB41 ZNF362 MEF2A MEF2D TLX1 ZFHX4 MTF1 YAP1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 NPAS2	1.92e-04	1244	122	19	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX5 POU2F1 ZBTB41 ZNF362 MEF2A MEF2D CASZ1 TLX1 USF3 ZFHX4 MTF1 YAP1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 NPAS2	1.94e-04	1459	122	21	GO:0000977
GeneOntologyMolecularFunction	molecular adaptor activity	HDAC9 KDM3A NCOA6 ZMYND11 PPRC1 NACA WWTR1 CHD4 SRCAP WNK1 ARID1B KMT2D GAS2L2 YAP1 PXN ELK1 KAT6B ZBED1 MED13 RBFOX2	2.04e-04	1356	122	20	GO:0060090
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	HDAC9 KDM3A NCOA6 CHD4 MEF2A MEF2D LATS1 ELK1 MED13 TP73	2.44e-04	417	122	10	GO:0061629
GeneOntologyMolecularFunction	protein phosphatase inhibitor activity	PPP1R8 SH3RF2 PPP1R37 CABIN1	2.46e-04	50	122	4	GO:0004864
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX5 POU2F1 ZBTB41 ZNF362 MEF2A MEF2D TLX1 ZFHX4 MTF1 YAP1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 NPAS2	2.53e-04	1271	122	19	GO:0000987
GeneOntologyMolecularFunction	phosphatase inhibitor activity	PPP1R8 SH3RF2 PPP1R37 CABIN1	3.31e-04	54	122	4	GO:0019212
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	NCOA6 PPRC1 ELK1 MED13	5.29e-04	61	122	4	GO:0030374
GeneOntologyMolecularFunction	histone acetyltransferase binding	MEF2A MTF1 PAX6	7.24e-04	29	122	3	GO:0035035
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A6 FN1 ABI3BP PAPLN MUC17 TNXB	1.05e-03	188	122	6	GO:0005201
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	KDM3A NCOA6 PPRC1 NACA POU2F1 WWTR1 MEF2A MEF2D CASZ1 TLX1 KMT2D USF3 GABPB2 MTF1 YAP1 MICAL2 SUPT6H ARID2 CAPRIN2 MITF ELK1 PAX6 ABLIM2 KAT6B ZBED1 MGA NFAT5 MED13 NEUROG3 TP73 ZNF292 NPAS2	2.48e-11	1390	124	32	GO:0045944
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PSG11 PCDHB13 PCDHB8 PCDHB18P PTPRG PCDHB1 SDK1 PCDH9	1.77e-05	187	124	8	GO:0007156
GeneOntologyBiologicalProcess	cell fate commitment	SOX5 CHD4 CASZ1 TLX1 LATS1 MITF PAX6 MGA TNXB IL6R	3.82e-05	338	124	10	GO:0045165
GeneOntologyCellularComponent	chromatin	SOX5 KDM3A BICRA POU2F1 CHD4 SRCAP MEF2A MEF2D CASZ1 TLX1 ARID1B ZFHX4 ARID2 MITF ELK1 PAX6 KAT6B ZBED1 MGA NFAT5 NEUROG3 TP73 RAD21 NPAS2	4.81e-06	1480	123	24	GO:0000785
GeneOntologyCellularComponent	nuclear protein-containing complex	HDAC9 KDM3A NCOA6 AFF2 SCAF8 BICRA RBM42 U2AF2 POU2F1 CHD4 SRCAP SAGE2P KHDC4 PPP1R8 ARID1B KMT2D YAP1 SUPT6H ARID2 SAGE1 MGA MED13 NPAS2	4.83e-06	1377	123	23	GO:0140513
GeneOntologyCellularComponent	transcription regulator complex	SOX5 HDAC9 NCOA6 POU2F1 WWTR1 CHD4 MEF2A YAP1 ARID2 PAX6 MGA NFAT5 NPAS2	5.04e-05	596	123	13	GO:0005667
GeneOntologyCellularComponent	rod spherule	PCLO MPP4	1.03e-04	3	123	2	GO:0044317
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	BICRA CHD4 SRCAP ARID1B ARID2	2.59e-04	96	123	5	GO:0070603
GeneOntologyCellularComponent	cone cell pedicle	PCLO MPP4	3.39e-04	5	123	2	GO:0044316
GeneOntologyCellularComponent	SWI/SNF complex	BICRA ARID1B ARID2	7.19e-04	30	123	3	GO:0016514
GeneOntologyCellularComponent	ATPase complex	BICRA CHD4 SRCAP ARID1B ARID2	1.00e-03	129	123	5	GO:1904949
GeneOntologyCellularComponent	histone methyltransferase complex	HDAC9 NCOA6 KMT2D MGA	1.01e-03	75	123	4	GO:0035097
HumanPheno	Prominent eyelashes	ARID1B KMT2D ARID2 VPS13B	8.79e-06	17	42	4	HP:0011231
HumanPheno	Abnormal mucociliary clearance	GAS2L2 TP73	6.64e-05	2	42	2	HP:0031602
HumanPheno	Abnormal cheek morphology	HDAC9 RPGRIP1 FN1 BICRA PCLO ARID1B KMT2D MITF KAT6B VPS13B	6.98e-05	282	42	10	HP:0004426
HumanPheno	Tetralogy of Fallot	BICRA CHD4 SRCAP CASZ1 ARID1B KMT2D ARID2 RAD21	1.06e-04	185	42	8	HP:0001636
HumanPheno	Hypertrichosis	SOX5 ZMYND11 BICRA SRCAP CASZ1 ARID1B KMT2D ARID2 MITF MED13 ZNF292 RAD21	1.06e-04	425	42	12	HP:0000998
HumanPheno	Abnormal size of the palpebral fissures	BICRA CAMK2G PCLO CHD4 SRCAP KMT2D ARID2 DNM1 KAT6B MED13	1.11e-04	298	42	10	HP:0200007
HumanPheno	Abnormal pinna morphology	SOX5 HDAC9 RPGRIP1 ZMYND11 AFF2 FN1 BICRA CAMK2G PCLO U2AF2 CHD4 SRCAP CASZ1 ARID1B KMT2D ARID2 MITF DNM1 KAT6B VPS13B ZNF292 RAD21	1.65e-04	1299	42	22	HP:0000377
HumanPheno	Autistic behavior	AFF2 BICRA U2AF2 NBEA SRCAP CASZ1 ARID1B KMT2D USF3 ARID2 DNM1 MED13 VPS13B ZNF292 RAD21	1.89e-04	678	42	15	HP:0000729
HumanPheno	Complex cardiac malformations	BICRA CHD4 SRCAP CASZ1 ARID1B KMT2D GAS2L2 ARID2 RAD21	1.89e-04	257	42	9	HP:0002565
HumanPheno	Abnormal location of ears	SOX5 RPGRIP1 FN1 BICRA CAMK2G PCLO U2AF2 CHD4 SRCAP CASZ1 ARID1B KMT2D ARID2 MITF DNM1 KAT6B ZNF292 RAD21	2.26e-04	945	42	18	HP:0000357
HumanPheno	Conotruncal defect	BICRA CHD4 SRCAP CASZ1 ARID1B KMT2D GAS2L2 ARID2 RAD21	2.32e-04	264	42	9	HP:0001710
HumanPheno	Abnormality of the outer ear	SOX5 HDAC9 RPGRIP1 ZMYND11 AFF2 FN1 BICRA CAMK2G PCLO U2AF2 CHD4 SRCAP CASZ1 ARID1B KMT2D ARID2 MITF DNM1 KAT6B VPS13B ZNF292 RAD21	2.59e-04	1337	42	22	HP:0000356
HumanPheno	Posteriorly rotated ears	SOX5 RPGRIP1 FN1 BICRA SRCAP CASZ1 ARID1B KMT2D ARID2 MITF KAT6B RAD21	2.78e-04	470	42	12	HP:0000358
HumanPheno	Abnormality of refraction	SOX5 RPGRIP1 COL4A6 FN1 BICRA CAMK2G CHD4 SRCAP CASZ1 ARID1B USF3 ARID2 PAX6 VPS13B RAD21	3.13e-04	709	42	15	HP:0000539
HumanPheno	Abnormality of the palpebral fissures	SOX5 ZMYND11 BICRA CAMK2G PCLO U2AF2 CHD4 SRCAP ARID1B KMT2D ARID2 DNM1 KAT6B MED13 VPS13B ZNF292 RAD21	3.15e-04	880	42	17	HP:0008050
MousePheno	abnormal fetal cardiomyocyte proliferation	NCOA6 NACA CHD4 CASZ1 ARID2 NFAT5	8.71e-07	48	96	6	MP:0003567
MousePheno	abnormal fetal cardiomyocyte physiology	NCOA6 NACA CHD4 CASZ1 ARID2 NFAT5	1.98e-06	55	96	6	MP:0011390
Domain	fn3	MYLK FN1 ABI3BP PTPRG TNXB SDK1 IL6R EPHB1	9.35e-06	162	119	8	PF00041
Domain	FN3	MYLK FN1 ABI3BP PTPRG TNXB SDK1 IL6R EPHB1	2.45e-05	185	119	8	SM00060
Domain	Paxillin	RAPH1 PXN	4.03e-05	2	119	2	IPR001904
Domain	FN3	MYLK FN1 ABI3BP PTPRG TNXB SDK1 IL6R EPHB1	4.12e-05	199	119	8	PS50853
Domain	Znf_FYVE_PHD	KDM3A ZMYND11 PCLO CHD4 PIKFYVE KMT2D KAT6B	4.35e-05	147	119	7	IPR011011
Domain	FN3_dom	MYLK FN1 ABI3BP PTPRG TNXB SDK1 IL6R EPHB1	5.83e-05	209	119	8	IPR003961
Domain	UBA	NACA UBAP1 LATS1 SIK2	2.26e-04	47	119	4	PS50030
Domain	HJURP_C	MEF2A MEF2D	2.40e-04	4	119	2	IPR022102
Domain	MADS_MEF2-like	MEF2A MEF2D	2.40e-04	4	119	2	IPR033896
Domain	HJURP_C	MEF2A MEF2D	2.40e-04	4	119	2	PF12347
Domain	MADS_BOX_1	MEF2A MEF2D	5.94e-04	6	119	2	PS00350
Domain	MADS	MEF2A MEF2D	5.94e-04	6	119	2	SM00432
Domain	SRF-TF	MEF2A MEF2D	5.94e-04	6	119	2	PF00319
Domain	MADS_BOX_2	MEF2A MEF2D	5.94e-04	6	119	2	PS50066
Domain	HLH	USF3 MITF MGA NEUROG3 NPAS2	7.22e-04	111	119	5	PF00010
Domain	Cadherin_2	PCDHB13 PCDHB8 PCDHB1 PCDH9	7.86e-04	65	119	4	PF08266
Domain	Cadherin_N	PCDHB13 PCDHB8 PCDHB1 PCDH9	7.86e-04	65	119	4	IPR013164
Domain	TF_MADSbox	MEF2A MEF2D	8.28e-04	7	119	2	IPR002100
Domain	HLH	USF3 MITF MGA NEUROG3 NPAS2	8.81e-04	116	119	5	SM00353
Domain	BHLH	USF3 MITF MGA NEUROG3 NPAS2	9.16e-04	117	119	5	PS50888
Domain	bHLH_dom	USF3 MITF MGA NEUROG3 NPAS2	9.52e-04	118	119	5	IPR011598
Pathway	WP_FOCAL_ADHESION	COL4A6 MYLK FN1 PDPK2P PXN ELK1 TNXB	1.24e-04	187	84	7	MM15913
Pathway	WP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION	MEF2A MEF2D ELK1	1.56e-04	18	84	3	M39393
Pathway	WP_ENERGY_METABOLISM	PPRC1 CAMK2G MEF2A MEF2D	1.87e-04	48	84	4	M39590
Pathway	REACTOME_SIGNALING_BY_HIPPO	WWTR1 LATS1 YAP1	2.16e-04	20	84	3	MM14813
Pathway	REACTOME_SIGNALING_BY_HIPPO	WWTR1 LATS1 YAP1	2.16e-04	20	84	3	M591
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX5 ZMYND11 POU2F1 ZBTB41 SRCAP MEF2A MEF2D MTF1 ARID2 PXN ELK1 PAX6 ABLIM2 KAT6B MGA NFAT5 NEUROG3 ZNF292 NPAS2	9.86e-11	808	125	19	20412781
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC9 KDM3A NCOA6 CHD4 SRCAP ARID1B KMT2D ARID2 PAX6 KAT6B	2.99e-10	157	125	10	30186101
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 ZMYND11 AFF2 BICRA TSC22D2 WNK1 USF3 LATS1 BAIAP2L1 YAP1 ARID2 MITF MGA TP73	5.57e-10	430	125	14	35044719
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX5 POU2F1 TSC22D2 MEF2A MEF2D TLX1 KMT2D USF3 ZFHX4 MTF1 MITF ELK1 PAX6 ZBED1 MGA NFAT5 NEUROG3 TP73 NPAS2	6.90e-10	908	125	19	19274049
Pubmed	Human transcription factor protein interaction networks.	SOX5 NCOA6 SCAF8 BICRA NACA POU2F1 SRCAP MEF2A MEF2D TLX1 ARID1B KMT2D ZFHX4 YAP1 PRRC2C ARID2 SEC24B MITF ZBTB40 PAX6 CABIN1 MGA RAD21	1.49e-09	1429	125	23	35140242
Pubmed	Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.	HDAC9 MEF2A MEF2D CABIN1	2.37e-09	6	125	4	10825153
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA6 CHD4 ZNF362 MEF2A MEF2D CASZ1 ARID1B KMT2D YAP1 MGA MED13	3.96e-09	268	125	11	33640491
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KDM3A ZMYND11 POU2F1 CHD4 ZNF362 SRCAP CASZ1 SBNO1 ARID2 ZBTB40 PAX6 CABIN1 MGA ZNF292 RAD21	5.67e-09	608	125	15	36089195
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SLAIN2 KDM3A NCOA6 RAPH1 WWTR1 SRCAP ARID1B KMT2D LATS1 YAP1 PRRC2C ARID2 SEC24B MGA	1.25e-08	549	125	14	38280479
Pubmed	Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.	WWTR1 LATS1 YAP1 MITF PAX6	1.39e-08	22	125	5	29249622
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SLAIN2 KDM3A NCOA6 BICRA NPEPPS CAMK2G POU2F1 CHD4 ZNF362 KHDC4 MEF2A MEF2D ARID1B KMT2D PRRC2C ARID2 ZBTB40 ZNF292 RAD21	1.62e-08	1103	125	19	34189442
Pubmed	Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.	WWTR1 MEF2A ARID1B YAP1 ARID2	2.23e-08	24	125	5	37543677
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	SOX5 BICRA PCLO CASZ1 ARID1B KMT2D ZFHX4 BAIAP2L1 ARID2 ELK1 MGA ZNF292	2.36e-08	398	125	12	35016035
Pubmed	Crosstalk between Hippo signalling and miRNAs in tumour progression.	WWTR1 LATS1 YAP1	4.53e-08	3	125	3	27973704
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PPRC1 PCLO SUSD5 MGA MED13 VPS13B ZNF292	1.11e-07	105	125	7	9628581
Pubmed	Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.	WWTR1 LATS1 YAP1	1.81e-07	4	125	3	28115535
Pubmed	Hippo signaling instructs ectopic but not normal organ growth.	WWTR1 LATS1 YAP1	1.81e-07	4	125	3	36395225
Pubmed	SUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions.	WWTR1 LATS1 YAP1	1.81e-07	4	125	3	27847303
Pubmed	Expression and prognostic significance of YAP, TAZ, TEAD4 and p73 in human laryngeal cancer.	WWTR1 YAP1 TP73	1.81e-07	4	125	3	32378727
Pubmed	A human MAP kinase interactome.	HDAC9 ABI3BP BICRA WWTR1 WNK1 MEF2D USF3 LATS1 ARID2 ABLIM2 MGA RBFOX2	2.05e-07	486	125	12	20936779
Pubmed	A unique role of cohesin-SA1 in gene regulation and development.	PCDHB13 PCDHB8 PCDHB18P RAD21	2.80e-07	16	125	4	22415368
Pubmed	Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	28416659
Pubmed	Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	32994166
Pubmed	Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	35191398
Pubmed	Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	26109051
Pubmed	Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	29438698
Pubmed	The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	31067451
Pubmed	Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP).	LATS1 YAP1 TP73	4.51e-07	5	125	3	18640976
Pubmed	Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	32796823
Pubmed	YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	28973878
Pubmed	YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation.	WWTR1 LATS1 YAP1	4.51e-07	5	125	3	28805663
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA6 POU2F1 ZNF362 ARID1B KMT2D ZNF292	5.75e-07	83	125	6	28794006
Pubmed	Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.	PCDHB13 PCDHB8 PCDHB18P RAD21	5.91e-07	19	125	4	23920377
Pubmed	Interaction network of human early embryonic transcription factors.	SOX5 NCOA6 BICRA POU2F1 ARID1B KMT2D ZFHX4 ARID2 MITF MGA	6.13e-07	351	125	10	38297188
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB13 PCDHB8 PCDHB18P PCDHB1	7.37e-07	20	125	4	11322959
Pubmed	Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	26503053
Pubmed	Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	31513574
Pubmed	RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein.	LATS1 YAP1 TP73	8.99e-07	6	125	3	17889669
Pubmed	Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	29689192
Pubmed	Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	36443313
Pubmed	YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	32341094
Pubmed	Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	31558567
Pubmed	Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface.	MYLK WWTR1 YAP1	8.99e-07	6	125	3	32338642
Pubmed	Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	38811804
Pubmed	The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.	WWTR1 LATS1 YAP1	8.99e-07	6	125	3	19289085
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPGRIP1 MYLK ABI3BP RAPH1 PPRC1 CAMK2G PCLO RBM42 U2AF2 ZBTB41 CHD4 SRCAP C2orf78 LATS1 SBNO1 PRRC2C CAPRIN2 MED13 ZNF292	9.97e-07	1442	125	19	35575683
Pubmed	YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	29669762
Pubmed	YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	32900774
Pubmed	YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	31801083
Pubmed	Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	31754005
Pubmed	Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	32960816
Pubmed	YAP1/TAZ drives ependymoma-like tumour formation in mice.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	32404936
Pubmed	YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis.	WWTR1 LATS1 YAP1	1.57e-06	7	125	3	30582452
Pubmed	The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number.	WWTR1 LATS1 YAP1 PAX6	1.60e-06	24	125	4	30523785
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SLAIN2 FN1 CHD4 WNK1 ARID1B SUPT6H ZBTB40 PXN ABLIM2 MGA MED13	1.95e-06	497	125	11	23414517
Pubmed	Hippo signaling regulates pancreas development through inactivation of Yap.	WWTR1 LATS1 YAP1 NEUROG3	2.24e-06	26	125	4	23071096
Pubmed	Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.	WWTR1 LATS1 YAP1	2.50e-06	8	125	3	32259481
Pubmed	Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.	HDAC9 MEF2A MEF2D	2.50e-06	8	125	3	17786239
Pubmed	A Stk4-Foxp3-NF-κB p65 transcriptional complex promotes Treg cell activation and homeostasis.	WWTR1 LATS1 YAP1	2.50e-06	8	125	3	36149942
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	FN1 RAPH1 MEF2A NFAT5 RBFOX2	2.58e-06	60	125	5	19075228
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SLAIN2 ZMYND11 BICRA U2AF2 CHD4 ZNF362 SRCAP ITIH4 ARID1B ZFHX4 ARID2 RTL9 CAPRIN2 KAT6B MGA TP73	2.67e-06	1116	125	16	31753913
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HDAC9 ZMYND11 POU2F1 WWTR1 CHD4 TLX1 MTF1 MITF ELK1 PAX6 RBFOX2 TP73 ZNF292 NPAS2	3.49e-06	877	125	14	20211142
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLAIN2 KDM3A NCOA6 NACA ARID1B SEMA5B SUPT6H CAPRIN2 KAT6B MED13 RAD21	3.54e-06	529	125	11	14621295
Pubmed	Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.	POU2F1 MEF2A MEF2D	3.75e-06	9	125	3	9738004
Pubmed	Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development.	WWTR1 LATS1 YAP1	3.75e-06	9	125	3	27160901
Pubmed	The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway.	U2AF2 WNK1 RBFOX2	3.75e-06	9	125	3	17289029
Pubmed	Maternal hepatocytes heterogeneously and dynamically exhibit developmental phenotypes partially via yes-associated protein 1 during pregnancy.	WWTR1 LATS1 YAP1	3.75e-06	9	125	3	36283963
Pubmed	Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest.	WWTR1 YAP1 MITF	3.75e-06	9	125	3	25466249
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NCOA6 RBM42 U2AF2 WWTR1 CHD4 SRCAP CASZ1 KMT2D TIGD2 YAP1 SUPT6H MITF PAX6 CABIN1 MGA RBFOX2 RAD21	4.08e-06	1294	125	17	30804502
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A NCOA6 RAPH1 SCAF8 POU2F1 CHD4 MEF2D KMT2D LATS1 YAP1 ZBTB40 KAT6B MED13	4.62e-06	774	125	13	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SLAIN2 AFF2 FN1 MUC16 U2AF2 NBEA CHD4 GORASP2 BAIAP2L1 SEC24B MGA SDK1 PCDH9	4.82e-06	777	125	13	35844135
Pubmed	A fibronectin gradient remodels mixed-phase mesoderm.	FN1 WWTR1 YAP1	5.34e-06	10	125	3	39028807
Pubmed	Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.	WWTR1 YAP1 IL6R	5.34e-06	10	125	3	33915108
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SCAF8 BICRA NPEPPS U2AF2 ZNF362 MEF2A CASZ1 USF3 PTPRG MICAL2 SUPT6H ABLIM2 KAT6B NFAT5 VPS13B IL6R RBFOX2 NPAS2	6.53e-06	1489	125	18	28611215
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB13 PCDHB8 PCDHB18P PCDHB1 PCDH9	7.31e-06	74	125	5	10817752
Pubmed	Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.	WWTR1 LATS1 YAP1	7.32e-06	11	125	3	29849151
Pubmed	Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity.	LATS1 YAP1 TP73	7.32e-06	11	125	3	25283809
Pubmed	LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation.	WWTR1 LATS1 YAP1	7.32e-06	11	125	3	36125128
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB13 PCDHB8 PCDHB18P PCDHB1 PCDH9	8.89e-06	77	125	5	10835267
Pubmed	WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.	WWTR1 LATS1 YAP1	9.74e-06	12	125	3	35429439
Pubmed	Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture.	FN1 WWTR1 YAP1	9.74e-06	12	125	3	30883226
Pubmed	TAZ is required for chondrogenesis and skeletal development.	SOX5 WWTR1 YAP1	9.74e-06	12	125	3	33879790
Pubmed	SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.	WWTR1 LATS1 YAP1	9.74e-06	12	125	3	34267330
Pubmed	The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.	LATS1 MTF1 YAP1	9.74e-06	12	125	3	35027733
Pubmed	Functional proteomics mapping of a human signaling pathway.	SOX5 NCOA6 ZMYND11 FN1 U2AF2 PPP1R8 ARID1B KMT2D PPP1R37 MGA SDK1	1.01e-05	591	125	11	15231748
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SOX5 POU2F1 CHD4 MEF2A MEF2D PIKFYVE MTF1 PXN PAX6 KAT6B NFAT5 ZNF292	1.01e-05	709	125	12	22988430
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB13 PCDHB8 PCDHB18P PCDHB1 PCDH9	1.07e-05	80	125	5	10716726
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL4A6 PAPLN SEMA5B CSPG5 PAX6 TNXB NEUROG3	1.16e-05	210	125	7	16537572
Pubmed	MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway.	WWTR1 LATS1 YAP1	1.26e-05	13	125	3	33571521
Pubmed	LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis.	WWTR1 YAP1 PAX6	1.26e-05	13	125	3	33510165
Pubmed	A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.	WWTR1 YAP1 IL6R	1.26e-05	13	125	3	32929274
Pubmed	The Hippo pathway regulates Wnt/beta-catenin signaling.	WWTR1 LATS1 YAP1	1.26e-05	13	125	3	20412773
Pubmed	YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells.	WWTR1 YAP1	1.28e-05	2	125	2	29115373
Pubmed	EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118.	PXN EPHB1	1.28e-05	2	125	2	15107421
Pubmed	SHP2 inhibition enhances Yes-associated protein-mediated liver regeneration in murine partial hepatectomy models.	WWTR1 YAP1	1.28e-05	2	125	2	35763355
Pubmed	A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.	WWTR1 YAP1	1.28e-05	2	125	2	23954413
Pubmed	YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction.	WWTR1 YAP1	1.28e-05	2	125	2	36350617
Pubmed	YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation.	WWTR1 YAP1	1.28e-05	2	125	2	34463254
Pubmed	Increased expression of yes-associated protein/YAP and transcriptional coactivator with PDZ-binding motif/TAZ activates intestinal fibroblasts to promote intestinal obstruction in Crohn's disease.	WWTR1 YAP1	1.28e-05	2	125	2	34186485
Pubmed	Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.	WWTR1 YAP1	1.28e-05	2	125	2	38105758
Interaction	PAX6 interactions	SOX5 NCOA6 BICRA POU2F1 SRCAP ARID1B KMT2D ZFHX4 GAS2L2 ARID2 MITF PAX6 CABIN1 ZBED1 MGA TP73 RAD21	9.10e-11	366	123	17	int:PAX6
Interaction	ASF1A interactions	NCOA6 BICRA ZNF362 SRCAP MEF2D CASZ1 CDAN1 ARID1B KMT2D ARID2 CABIN1 MGA TP73	4.21e-09	249	123	13	int:ASF1A
Interaction	NFIX interactions	SOX5 BICRA POU2F1 SRCAP ARID1B KMT2D ZFHX4 ARID2 ZBTB40 PAX6 MGA RAD21	1.49e-08	227	123	12	int:NFIX
Interaction	HNF1B interactions	SOX5 BICRA MEF2D ARID1B KMT2D ZFHX4 YAP1 ARID2 PAX6 CABIN1 MGA	2.41e-08	190	123	11	int:HNF1B
Interaction	SP7 interactions	SOX5 NCOA6 SCAF8 BICRA POU2F1 MEF2A MEF2D ARID1B KMT2D ZFHX4 ARID2 MITF MGA	4.51e-08	304	123	13	int:SP7
Interaction	CREBBP interactions	NCOA6 WWTR1 SRCAP TLX1 PPP1R8 ARID1B KMT2D LATS1 MTF1 YAP1 SUPT6H MITF ELK1 PAX6 MGA TP73 NPAS2	1.41e-07	599	123	17	int:CREBBP
Interaction	MEF2B interactions	HDAC9 MEF2A MEF2D CABIN1	4.22e-07	11	123	4	int:MEF2B
Interaction	FEV interactions	SOX5 NCOA6 BICRA POU2F1 ARID1B KMT2D ZFHX4 YAP1 ARID2 MGA	4.81e-07	203	123	10	int:FEV
Interaction	H3-3A interactions	HDAC9 KDM3A ZMYND11 U2AF2 POU2F1 CHD4 ZNF362 SRCAP CASZ1 KMT2D SBNO1 ARID2 ZBTB40 PAX6 CABIN1 MGA ZNF292 RAD21	6.76e-07	749	123	18	int:H3-3A
Interaction	SOX7 interactions	SOX5 CASZ1 ARID1B KMT2D ZFHX4 ARID2 ZNF292	6.91e-07	82	123	7	int:SOX7
Interaction	EGR2 interactions	SOX5 NCOA6 BICRA ARID1B KMT2D ZFHX4 ARID2 MITF MGA	1.06e-06	171	123	9	int:EGR2
Interaction	SOX2 interactions	SOX5 SLAIN2 NCOA6 FN1 NPEPPS POU2F1 CHD4 ZNF362 MEF2A MEF2D ITIH4 TLX1 SCRN2 ARID1B KMT2D ZFHX4 YAP1 ARID2 MITF PAX6 KAT6B RBFOX2 TP73 ZNF292 RAD21	1.32e-06	1422	123	25	int:SOX2
Interaction	TEAD1 interactions	WWTR1 MEF2A MEF2D ARID1B KMT2D ZFHX4 YAP1 ARID2 MGA	1.35e-06	176	123	9	int:TEAD1
Interaction	WWTR1 interactions	SLAIN2 HDAC9 NCOA6 RAPH1 WWTR1 SRCAP ARID1B KMT2D LATS1 YAP1 PRRC2C ARID2 SEC24B	1.89e-06	422	123	13	int:WWTR1
Interaction	LHX1 interactions	MEF2D ARID1B KMT2D ZFHX4 ARID2 MGA RAD21	3.24e-06	103	123	7	int:LHX1
Interaction	ZYX interactions	FN1 ZNRD2 UBAP1 U2AF2 WWTR1 TSC22D2 WNK1 LATS1 YAP1 PXN ABLIM2	5.63e-06	329	123	11	int:ZYX
Interaction	AR interactions	KDM3A NCOA6 FN1 U2AF2 POU2F1 CHD4 ZNF362 SRCAP MEF2A MEF2D CASZ1 ARID1B KMT2D YAP1 ARID2 PXN PAX6 MGA MED13	9.00e-06	992	123	19	int:AR
Interaction	KMT2D interactions	SOX5 NCOA6 WWTR1 MEF2D TLX1 KMT2D YAP1 PAX6	9.41e-06	169	123	8	int:KMT2D
Interaction	UBE2I interactions	SOX5 ZMYND11 ZNRD2 CAMK2G POU2F1 CHD4 WNK1 MEF2A LATS1 MITF ELK1 DNM1 KAT6B ZBED1 TP73	1.09e-05	654	123	15	int:UBE2I
Interaction	CABIN1 interactions	MEF2A MEF2D CDAN1 PAX6 DNM1 CABIN1	1.18e-05	83	123	6	int:CABIN1
Interaction	HDAC1 interactions	HDAC9 ZMYND11 FN1 RAPH1 CAMK2G U2AF2 POU2F1 CHD4 MEF2A MEF2D CASZ1 KMT2D ZFHX4 YAP1 PXN ELK1 CABIN1 MGA TP73 RAD21	1.21e-05	1108	123	20	int:HDAC1
Interaction	LHX2 interactions	MEF2D ARID1B KMT2D ZFHX4 ARID2 PAX6 MGA RAD21	1.68e-05	183	123	8	int:LHX2
Interaction	LHX3 interactions	SOX5 MEF2D ARID1B KMT2D ZFHX4 GAS2L2 ARID2 MGA	1.82e-05	185	123	8	int:LHX3
Interaction	TLE3 interactions	KDM3A ZNRD2 SCAF8 ZNF362 KHDC4 TLX1 ARID1B KMT2D ARID2 SAGE1 PAX6	1.96e-05	376	123	11	int:TLE3
Interaction	CRX interactions	SOX5 BICRA POU2F1 ARID1B KMT2D ZFHX4 ARID2 MGA NPAS2	2.63e-05	254	123	9	int:CRX
Interaction	KLF5 interactions	NCOA6 WWTR1 MEF2D ARID1B KMT2D YAP1 ARID2 MGA	2.65e-05	195	123	8	int:KLF5
Interaction	ASH2L interactions	NCOA6 WWTR1 SRCAP MEF2D KMT2D YAP1 PAX6 MGA ZNF292	3.66e-05	265	123	9	int:ASH2L
Interaction	ARID2 interactions	BICRA WWTR1 TSC22D2 ARID1B YAP1 ARID2 PAX6	4.31e-05	153	123	7	int:ARID2
Interaction	ZFHX3 interactions	SOX5 POU2F1 CHD4 TLX1 ZFHX4 PAX6	5.54e-05	109	123	6	int:ZFHX3
Interaction	CEBPA interactions	SLAIN2 RPGRIP1 KDM3A NCOA6 BICRA NPEPPS CAMK2G POU2F1 CHD4 ZNF362 KHDC4 MEF2A MEF2D ARID1B KMT2D PRRC2C ARID2 ZBTB40 ZNF292 RAD21	6.36e-05	1245	123	20	int:CEBPA
Interaction	SUMO1 interactions	HDAC9 ZNRD2 MEF2A YAP1 MITF PAX6 DNM1 ZBED1 TP73	6.78e-05	287	123	9	int:SUMO1
Interaction	SMARCB1 interactions	BICRA CHD4 SRCAP TLX1 GORASP2 ARID1B YAP1 ARID2 PAX6 CABIN1	8.03e-05	364	123	10	int:SMARCB1
Interaction	ZFHX4 interactions	SOX5 CHD4 TLX1 ZFHX4 PAX6	8.41e-05	73	123	5	int:ZFHX4
Interaction	ZMYM4 interactions	SOX5 CHD4 TLX1 YAP1 RTL9 PAX6 NEUROG3	8.71e-05	171	123	7	int:ZMYM4
Interaction	BORCS8-MEF2B interactions	MEF2A MEF2D CABIN1	9.57e-05	15	123	3	int:BORCS8-MEF2B
Interaction	TP53BP1 interactions	NCOA6 NPEPPS U2AF2 WWTR1 MEF2A PPP1R8 ARID1B SAGE1 CABIN1 MGA MED13 TP73	1.04e-04	533	123	12	int:TP53BP1
Interaction	ARID1B interactions	BICRA WWTR1 TLX1 ARID1B YAP1 ARID2 PAX6	1.08e-04	177	123	7	int:ARID1B
Interaction	BCL7A interactions	SOX5 BICRA TLX1 ARID1B ARID2 PAX6	1.09e-04	123	123	6	int:BCL7A
Interaction	EP300 interactions	NCOA6 NACA U2AF2 WWTR1 CHD4 SRCAP MEF2A MEF2D TLX1 KMT2D SBNO1 MTF1 YAP1 SUPT6H SEC24B MITF SIK2 ELK1 PAX6 TP73 NPAS2	1.09e-04	1401	123	21	int:EP300
Interaction	BAG2 interactions	NCOA6 FN1 POU2F1 CHD4 WNK1 MEF2D YAP1 SUPT6H PRRC2C SIK2 PXN ELK1 VPS13B	1.12e-04	622	123	13	int:BAG2
Interaction	SMARCC1 interactions	BICRA WWTR1 CHD4 SRCAP TLX1 ARID1B LATS1 YAP1 ARID2 PAX6	1.25e-04	384	123	10	int:SMARCC1
Interaction	SMARCA4 interactions	HDAC9 ZMYND11 BICRA WWTR1 CHD4 SRCAP ARID1B YAP1 ARID2 PAX6 CABIN1	1.25e-04	462	123	11	int:SMARCA4
Interaction	FOS interactions	NCOA6 NACA ARID1B KMT2D ARID2 MITF ELK1 MGA NFAT5	1.28e-04	312	123	9	int:FOS
Interaction	SMARCD2 interactions	BICRA CHD4 TLX1 ARID1B ARID2 PAX6 TP73	1.33e-04	183	123	7	int:SMARCD2
Interaction	SNRNP40 interactions	KDM3A SCAF8 RBM42 U2AF2 ZNF362 KHDC4 PPP1R8 ARID1B SUPT6H ARID2 SAGE1 MGA RBFOX2	1.41e-04	637	123	13	int:SNRNP40
Interaction	TEAD2 interactions	POU2F1 WWTR1 CHD4 CASZ1 ZFHX4 YAP1	1.47e-04	130	123	6	int:TEAD2
Interaction	SMG7 interactions	NCOA6 SCAF8 U2AF2 WWTR1 MEF2D ARID1B KMT2D LATS1 PXN	1.51e-04	319	123	9	int:SMG7
Interaction	MED15 interactions	NCOA6 CHD4 SRCAP YAP1 MED13 TP73	1.53e-04	131	123	6	int:MED15
Interaction	PAX2 interactions	POU2F1 ARID1B KMT2D ZFHX4 MGA	1.73e-04	85	123	5	int:PAX2
Interaction	MAU2 interactions	SLAIN2 BICRA SRCAP SUPT6H MGA MED13	1.88e-04	136	123	6	int:MAU2
Interaction	KLF8 interactions	SOX5 BICRA POU2F1 MEF2D KMT2D PRRC2C ARID2 MGA RAD21	1.90e-04	329	123	9	int:KLF8
Interaction	MEF2D interactions	MEF2A MEF2D TLX1 KMT2D CABIN1	1.93e-04	87	123	5	int:MEF2D
Interaction	GSC interactions	SOX5 POU2F1 ARID1B KMT2D ZFHX4	1.93e-04	87	123	5	int:GSC
Interaction	PHF10 interactions	BICRA ARID1B GAS2L2 ARID2 PAX6 NEUROG3	2.12e-04	139	123	6	int:PHF10
Interaction	UBN2 interactions	TLX1 CDAN1 YAP1 PAX6 CABIN1	2.15e-04	89	123	5	int:UBN2
Interaction	S100A2 interactions	SOX5 SLAIN2 POU2F1 NHSL1 KMT2D LATS1 SIK2 PPP1R37 PAX6 ZBED1	2.20e-04	412	123	10	int:S100A2
Interaction	POGZ interactions	SOX5 POU2F1 WWTR1 CHD4 TLX1 YAP1 PAX6 MGA	2.25e-04	265	123	8	int:POGZ
Interaction	H3C3 interactions	KDM3A POU2F1 CHD4 ZNF362 SRCAP CDAN1 SBNO1 SUPT6H ARID2 MGA ZNF292	2.28e-04	495	123	11	int:H3C3
Interaction	ZHX1 interactions	SOX5 ZMYND11 NACA PAX6 ZBED1	2.39e-04	91	123	5	int:ZHX1
Interaction	SOX10 interactions	ARID1B KMT2D ARID2 MITF PAX6	2.51e-04	92	123	5	int:SOX10
Interaction	PAGR1 interactions	NCOA6 TLX1 KMT2D PAX6	2.65e-04	51	123	4	int:PAGR1
Interaction	SMARCA2 interactions	ZMYND11 BICRA CHD4 TLX1 KIF9 ARID1B YAP1 ARID2 PAX6	2.76e-04	346	123	9	int:SMARCA2
Interaction	ALOXE3 interactions	POU2F1 NBEA ZFHX4 ZBED1	2.85e-04	52	123	4	int:ALOXE3
Interaction	HNF4A interactions	NCOA6 BICRA SRCAP ARID1B KMT2D ARID2 CABIN1 MGA	2.89e-04	275	123	8	int:HNF4A
Interaction	PFN1 interactions	SLAIN2 FN1 RAPH1 CAMK2G PCLO NBEA WNK1 NHSL1 BAIAP2L1 SEC24B DNM1	2.89e-04	509	123	11	int:PFN1
Interaction	SOX17 interactions	NCOA6 POU2F1 ARID1B KMT2D ARID2	2.92e-04	95	123	5	int:SOX17
Interaction	DPF1 interactions	BICRA TLX1 ARID1B ARID2 PAX6	2.92e-04	95	123	5	int:DPF1
Interaction	ARID1A interactions	BICRA WWTR1 CHD4 TLX1 ARID1B YAP1 ARID2 PAX6	2.96e-04	276	123	8	int:ARID1A
Interaction	PKD1 interactions	HDAC9 FN1 PTPRG PXN	3.07e-04	53	123	4	int:PKD1
Interaction	NFIC interactions	SOX5 POU2F1 TLX1 ARID1B KMT2D PAX6 MGA	3.09e-04	210	123	7	int:NFIC
Interaction	ATXN1L interactions	SOX5 SHISA2 TLX1 GORASP2 PAX6 RBFOX2	3.20e-04	150	123	6	int:ATXN1L
Interaction	SOX9 interactions	NCOA6 ARID1B KMT2D ARID2 PAX6	3.21e-04	97	123	5	int:SOX9
Interaction	QSER1 interactions	SOX5 WWTR1 TLX1 SEC24B PAX6	3.70e-04	100	123	5	int:QSER1
Interaction	NCOR1 interactions	SOX5 HDAC9 ZMYND11 WWTR1 SRCAP TLX1 YAP1 PAX6 MGA	3.92e-04	363	123	9	int:NCOR1
Interaction	H3C1 interactions	ZMYND11 NACA CHD4 SRCAP PIKFYVE CDAN1 KMT2D PRRC2C ARID2 PXN KAT6B CABIN1 MGA ZNF292 RAD21	3.93e-04	901	123	15	int:H3C1
Interaction	ELF2 interactions	POU2F1 SRCAP ZBTB40 PAX6 MGA EPHB1	3.94e-04	156	123	6	int:ELF2
Interaction	ZNF503 interactions	SOX5 TLX1 ARID1B PAX6	4.06e-04	57	123	4	int:ZNF503
Interaction	DACH1 interactions	SOX5 U2AF2 TLX1 YAP1 PAX6	4.43e-04	104	123	5	int:DACH1
Interaction	ERG interactions	NCOA6 BICRA MEF2D ARID1B KMT2D ZFHX4 MITF	4.43e-04	223	123	7	int:ERG
Interaction	TRIM37 interactions	SLAIN2 RPGRIP1 SCAF8 CAMK2G NACA U2AF2 MEF2D KIF9 KMT2D YAP1 SEC24B MGA	4.79e-04	630	123	12	int:TRIM37
Interaction	KDM6A interactions	NCOA6 WWTR1 TLX1 KMT2D YAP1 PAX6	4.82e-04	162	123	6	int:KDM6A
Interaction	SOX5 interactions	SOX5 POU2F1 KMT2D ZFHX4 PRRC2C PAX6	4.82e-04	162	123	6	int:SOX5
Interaction	FLNB interactions	ZMYND11 FN1 CAMK2G TSC22D2 YAP1 PRRC2C CAPRIN2 RAD21	5.62e-04	304	123	8	int:FLNB
Interaction	TERF2IP interactions	KDM3A NCOA6 ZNF362 SRCAP MEF2D SCRN2 SBNO1 SUPT6H MGA ZNF292 RAD21	5.72e-04	552	123	11	int:TERF2IP
Interaction	MAFA interactions	NCOA6 KMT2D PAX6	5.83e-04	27	123	3	int:MAFA
Interaction	SMAD2 interactions	NCOA6 ZMYND11 CAMK2G U2AF2 WWTR1 MEF2A ARID1B YAP1 TP73	5.99e-04	385	123	9	int:SMAD2
Interaction	PRMT5 interactions	KDM3A FN1 U2AF2 POU2F1 MEF2D ARID1B SBNO1 MTF1 YAP1 RBFOX2	6.30e-04	471	123	10	int:PRMT5
Interaction	TBR1 interactions	SOX5 ARID1B KMT2D LATS1 ZFHX4	6.48e-04	113	123	5	int:TBR1
Interaction	ARID3B interactions	WWTR1 TLX1 YAP1 PAX6 NEUROG3	6.48e-04	113	123	5	int:ARID3B
Interaction	BCL7C interactions	BICRA TLX1 ARID1B ARID2 PAX6	7.01e-04	115	123	5	int:BCL7C
Interaction	H4C4 interactions	FN1 CHD4 RAD21	7.22e-04	29	123	3	int:H4C4
Interaction	TBXT interactions	NCOA6 ARID1B KMT2D ZFHX4 YAP1	7.29e-04	116	123	5	int:TBXT
Interaction	PPP1R13B interactions	ZNRD2 WWTR1 KIF9 LATS1 GAS2L2 TP73	7.45e-04	176	123	6	int:PPP1R13B
Interaction	MYL9 interactions	MYLK YAP1 SIK2 TP73	7.53e-04	67	123	4	int:MYL9
Interaction	BICRA interactions	BICRA ARID1B ARID2 PAX6	7.53e-04	67	123	4	int:BICRA
Interaction	AHNAK interactions	FN1 RAPH1 U2AF2 CHD4 GORASP2 YAP1 PRRC2C NEUROG3	7.54e-04	318	123	8	int:AHNAK
Interaction	NFYC interactions	BICRA USF3 ARID2 PAX6 MGA TP73	7.67e-04	177	123	6	int:NFYC
Interaction	HECW2 interactions	RBM42 SRCAP BAIAP2L1 YAP1 RTL9 CABIN1 TP73 RAD21	8.18e-04	322	123	8	int:HECW2
GeneFamily	Fibronectin type III domain containing	MYLK FN1 ABI3BP PTPRG TNXB SDK1 EPHB1	1.30e-05	160	88	7	555
GeneFamily	CD molecules\|Mucins	MUC16 OVGP1 MUC17	1.39e-04	21	88	3	648
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2A MEF2D	1.40e-04	4	88	2	649
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2A MEF2D	2.32e-04	5	88	2	1086
GeneFamily	Clustered protocadherins	PCDHB13 PCDHB8 PCDHB18P PCDHB1	2.66e-04	64	88	4	20
GeneFamily	PHD finger proteins	ZMYND11 CHD4 KMT2D KAT6B	9.73e-04	90	88	4	88
GeneFamily	AT-rich interaction domain containing	ARID1B ARID2	2.36e-03	15	88	2	418
GeneFamily	LIM domain containing	MICAL2 PXN ABLIM2	2.98e-03	59	88	3	1218
GeneFamily	RNA binding motif containing	PPRC1 SCAF8 RBM42 U2AF2 RBFOX2	3.84e-03	213	88	5	725
Coexpression	RODRIGUES_NTN1_TARGETS_DN	MYLK FN1 RAPH1 CAMK2G WNK1 CHRM1 ARID1B PXN NFAT5	7.20e-08	161	123	9	M11857
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KDM3A ZMYND11 SCAF8 NPEPPS WWTR1 TSC22D2 MEF2A PIKFYVE YAP1 MICAL2 PRRC2C SEC24B MITF KAT6B MED13 VPS13B RBFOX2 ZNF292	1.05e-07	856	123	18	M4500
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	NPEPPS WNK1 SBNO1 PRRC2C TMEM245 ZBTB40 NFAT5 MED13 RAD21	1.87e-07	180	123	9	M8239
Coexpression	LAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET	WWTR1 TSC22D2 MEF2A ARID1B SIK2 NFAT5 SDK1 PCDH9 ZNF292	2.07e-06	240	123	9	M39236
Coexpression	TURJANSKI_MAPK14_TARGETS	MEF2A ELK1 TP73	1.18e-05	10	123	3	M14718
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	ZMYND11 SCAF8 NPEPPS PIKFYVE YAP1 PRRC2C SEC24B KAT6B MED13 RBFOX2 ZNF292	1.29e-05	466	123	11	M13522
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	WWTR1 WNK1 MEF2A YAP1 MITF NFAT5 PCDH9	1.67e-05	171	123	7	M39234
Coexpression	MARTINEZ_RB1_TARGETS_UP	SOX5 ZMYND11 PSG11 SHISA2 CHD4 APOC2 PDPK2P MEF2A NHSL1 PTPRG MGA RBFOX2 RAD21	4.69e-05	741	123	13	MM1037
Coexpression	LAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX	NBEA WWTR1 ARID1B SIK2 NFAT5 SDK1	5.52e-05	141	123	6	M39235
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN	BICRA MEF2D ARID1B ZBTB40 IL6R EPHB1	9.33e-05	155	123	6	M8944
Coexpression	WANG_MLL_TARGETS	SOX5 HDAC9 ABI3BP PCDHB13 PCDHB8 BAIAP2L1 SH3RF2 PAX6	1.02e-04	306	123	8	MM1076
Coexpression	KONDO_EZH2_TARGETS	MYLK ABI3BP PCLO WWTR1 MEF2D IL6R NPAS2	1.07e-04	229	123	7	M5301
Coexpression	GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP	HDAC9 MEF2A CRYBA1 NHSL1 ARID2 SEC24B	1.15e-04	161	123	6	M7728
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	WNK1 ARID1B PRRC2C ARID2 NFAT5 SDK1 MED13 ZNF292 RAD21	3.78e-09	193	124	9	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	WNK1 ARID1B ARID2 NFAT5 SDK1 MED13 ZNF292 RAD21	6.86e-08	192	124	8	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYLK FN1 ABI3BP PTPRG YAP1 TNXB SDK1	7.73e-08	195	124	8	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 NHSL1 ARID1B PTPRG YAP1 SDK1 VPS13B RBFOX2	8.69e-08	198	124	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	HDAC9 MYLK FN1 CAMK2G YAP1 SUSD5 SDK1	8.28e-07	183	124	7	818fd886e0188091310825f9145fa53328f2c979
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HDAC9 MYLK FN1 CAMK2G YAP1 SUSD5 SDK1	8.28e-07	183	124	7	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B PTPRG YAP1 TMEM245 NFAT5 SDK1 MED13	9.23e-07	186	124	7	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B PTPRG YAP1 TMEM245 NFAT5 SDK1 MED13	9.23e-07	186	124	7	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	HDAC9 MYLK FN1 CAMK2G YAP1 MICAL2 SDK1	9.91e-07	188	124	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HDAC9 MYLK FN1 CAMK2G YAP1 MICAL2 SDK1	1.03e-06	189	124	7	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SOX5 FN1 ABI3BP PTPRG TNXB SDK1 RBFOX2	1.03e-06	189	124	7	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A6 AFF2 MYLK ITIH4 SH3RF2 SUSD5 NPAS2	1.14e-06	192	124	7	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	POU2F1 ZBTB41 USF3 LATS1 MGA MED13 VPS13B	1.18e-06	193	124	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYLK FN1 ABI3BP PTPRG YAP1 RBFOX2	1.18e-06	193	124	7	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO NBEA CHD4 PRRC2C PAX6 MGA IL6R	1.27e-06	195	124	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO NBEA CHD4 PRRC2C PAX6 MGA IL6R	1.27e-06	195	124	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 ARID1B PTPRG YAP1 SDK1 VPS13B RBFOX2	1.31e-06	196	124	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 MYLK FN1 ABI3BP PTPRG TNXB SDK1	1.31e-06	196	124	7	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYLK FN1 ABI3BP PTPRG YAP1 SDK1	1.35e-06	197	124	7	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FN1 ABI3BP WWTR1 SSC5D ZFHX4 PTPRG RBFOX2	1.45e-06	199	124	7	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 ABI3BP RAPH1 SHISA2 ZFHX4 SUSD5 PCDH9	1.50e-06	200	124	7	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 ABI3BP RAPH1 SHISA2 ZFHX4 SUSD5 PCDH9	1.50e-06	200	124	7	d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 ABI3BP RAPH1 SHISA2 ZFHX4 SUSD5 PCDH9	1.50e-06	200	124	7	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SOX5 MYLK ABI3BP NBEA SSC5D ZFHX4 TNXB	1.50e-06	200	124	7	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP RAPH1 SHISA2 ZFHX4 SUSD5 PCDH9	1.50e-06	200	124	7	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RPGRIP1 FN1 SSC5D PTPRG MICAL2	6.94e-06	165	124	6	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RPGRIP1 FN1 SSC5D PTPRG MICAL2	6.94e-06	165	124	6	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RPGRIP1 FN1 SSC5D PTPRG MICAL2	6.94e-06	165	124	6	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	POU2F1 CHD4 ARID1B USF3 C19orf44 MGA	7.18e-06	166	124	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SOX5 NCOA6 ITIH4 PTPRG SDK1 RBFOX2	7.18e-06	166	124	6	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	SOX5 MYLK FN1 CAMK2G YAP1 SUSD5	8.51e-06	171	124	6	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC9 FN1 RAPH1 MICAL2 PCDH9	8.80e-06	172	124	6	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC9 FN1 RAPH1 MICAL2 PCDH9	8.80e-06	172	124	6	553701349444eb366df3c11f54bb093434f153c6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYLK ABI3BP PAPLN SSC5D PTPRG TNXB	9.71e-06	175	124	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ABI3BP ZNF831 CDAN1 USF3 SIK2 IL6R	9.71e-06	175	124	6	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP RAB44 SSC5D DNM1 TNXB	1.14e-05	180	124	6	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RAPH1 ZFHX4 BAIAP2L1 NFAT5 NPAS2	1.14e-05	180	124	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A6 MYLK FN1 PAPLN SSC5D TNXB	1.18e-05	181	124	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D MITF DNM1 TNXB	1.33e-05	185	124	6	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D MITF DNM1 TNXB	1.33e-05	185	124	6	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D MITF DNM1 TNXB	1.33e-05	185	124	6	a94694e226856bc5b168464f52d76004145717a5
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FN1 ABI3BP SSC5D DNM1 CABIN1 EPHB1	1.33e-05	185	124	6	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SOX5 HDAC9 MEF2A PIKFYVE SUSD5 PCDH9	1.37e-05	186	124	6	d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYLK FN1 PTPRG YAP1 SDK1	1.41e-05	187	124	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	MYLK FN1 ABI3BP PTPRG TNXB SDK1	1.41e-05	187	124	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	MYLK FN1 PTPRG ABLIM2 TNXB SDK1	1.41e-05	187	124	6	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	MYLK FN1 ABI3BP SSC5D PTPRG TNXB	1.41e-05	187	124	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 WNK1 CASZ1 MITF NFAT5 PCDH9	1.46e-05	188	124	6	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 WNK1 CASZ1 YAP1 MITF NFAT5	1.50e-05	189	124	6	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZMYND11 ZNF831 CHRM1 SBNO1 MICAL2 SUPT6H	1.50e-05	189	124	6	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	MYLK FN1 ABI3BP PTPRG TNXB SDK1	1.55e-05	190	124	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK FN1 ABI3BP WWTR1 ABLIM2 TNXB	1.64e-05	192	124	6	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	SOX5 COL4A6 WWTR1 SH3RF2 YAP1 SDK1	1.64e-05	192	124	6	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 ABI3BP PCLO ZFHX4 MICAL2 TNXB	1.64e-05	192	124	6	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYLK FN1 ABI3BP PTPRG TNXB SDK1	1.69e-05	193	124	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	LA\|World / Chamber and Cluster_Paper	SOX5 FN1 ABI3BP DNM1 TNXB SDK1	1.69e-05	193	124	6	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWTR1 CASZ1 PTPRG YAP1 MICAL2 TMEM245	1.74e-05	194	124	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	MYLK FN1 ABI3BP PTPRG YAP1 SDK1	1.90e-05	197	124	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	MYLK FN1 ABI3BP PTPRG TNXB SDK1	2.01e-05	199	124	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	SOX5 PCLO NACA NBEA PCDH9 RBFOX2	2.01e-05	199	124	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SOX5 MYLK ABI3BP SSC5D ZFHX4 TNXB	2.01e-05	199	124	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	SOX5 PCLO NACA NBEA PCDH9 RBFOX2	2.01e-05	199	124	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK FN1 ABI3BP PTPRG TNXB SDK1	2.07e-05	200	124	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 ABI3BP ZFHX4 PTPRG DNM1 PCDH9	2.07e-05	200	124	6	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SOX5 AFF2 MYLK ABI3BP SSC5D SUSD5	2.07e-05	200	124	6	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCLO MUC16 NBEA CASZ1 BAIAP2L1 NPAS2	2.07e-05	200	124	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	PCLO NBEA MICAL2 DNM1 ABLIM2 RBFOX2	2.07e-05	200	124	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SOX5 AFF2 MYLK FN1 ABI3BP SSC5D	2.07e-05	200	124	6	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 ABI3BP PTPRG DNM1 TNXB PCDH9	2.07e-05	200	124	6	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CAMK2G PAPLN NHSL1 YAP1 PAX6 EPHB1	2.07e-05	200	124	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	SOX5 PCLO SHISA2 NBEA NHSL1 RBFOX2	2.07e-05	200	124	6	0cb0755a101ec655359d051d6a8807408d727c55
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	SLAIN2 ZMYND11 SBNO1 PRRC2C ZNF292	4.24e-05	138	124	5	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MFSD6 WWTR1 SSC5D PTPRG ELK1	4.54e-05	140	124	5	276b3fa924176426efb31112ed4d355407f0b218
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NCOA6 MUC16 RAB44 CASZ1 TNXB	7.14e-05	154	124	5	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	MYLK FN1 ABI3BP PTPRG TNXB	8.30e-05	159	124	5	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RAPH1 NBEA SEMA5B PCDH9	8.30e-05	159	124	5	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 COL4A6 WNK1 CASZ1 SDK1	9.07e-05	162	124	5	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RAPH1 PCDHB13 SSC5D MICAL2	9.61e-05	164	124	5	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 COL4A6 MYLK FN1 SSC5D	9.61e-05	164	124	5	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 COL4A6 WNK1 CASZ1 SDK1	9.61e-05	164	124	5	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP CHRM1 SSC5D TNXB	9.89e-05	165	124	5	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCLO ZFHX4 SH3RF2 PAX6 ZBED1	1.02e-04	166	124	5	9fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 MYLK PCDHB13 PTPRG GABPB2	1.02e-04	166	124	5	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK ITIH4 SUSD5 TNXB NPAS2	1.05e-04	167	124	5	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive\|lymph-node_spleen / Manually curated celltypes from each tissue	SOX5 HDAC9 PIKFYVE SUSD5 PCDH9	1.08e-04	168	124	5	494d5a11154ff22fedb25f4036d730cef376da60
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D DNM1 TNXB	1.11e-04	169	124	5	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D DNM1 TNXB	1.11e-04	169	124	5	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ABI3BP SSC5D DNM1 TNXB	1.11e-04	169	124	5	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RAPH1 NBEA SEMA5B PCDH9	1.14e-04	170	124	5	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 RAPH1 NBEA SEMA5B PCDH9	1.14e-04	170	124	5	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ABI3BP ZNF831 CDAN1 SIK2 IL6R	1.20e-04	172	124	5	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	MYLK ABI3BP PAPLN DNM1 SDK1	1.20e-04	172	124	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK MEF2D ITIH4 MICAL2 SUSD5	1.23e-04	173	124	5	fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK MEF2D ITIH4 MICAL2 SUSD5	1.23e-04	173	124	5	901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SOX5 HDAC9 NBEA PTPRG PCDH9	1.27e-04	174	124	5	8393f0b43c767839c1630bcb952d62b42efc788d
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A	KDM3A NACA POU2F1 TSC22D2 KHDC4 ZBTB40 NFAT5 ZNF292	3.41e-06	166	123	8	5324_UP
Drug	Lanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A	KDM3A NACA POU2F1 ZBTB40 NFAT5 PCDH9 ZNF292 NPAS2	4.83e-06	174	123	8	6048_UP
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	PPRC1 SCAF8 TSC22D2 PPP1R8 SEC24B ZBTB40 MGA ZNF292	7.29e-06	184	123	8	2321_DN
Drug	Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	U2AF2 WWTR1 CHD4 WNK1 MICAL2 PRRC2C KAT6B RBFOX2	9.22e-06	190	123	8	4114_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	BICRA WWTR1 WNK1 PTPRG MICAL2 SUPT6H SIK2 PXN	1.11e-05	195	123	8	1649_DN
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A	MYLK PPRC1 CHD4 SRCAP OVGP1 MTF1 SUPT6H ZBTB40	1.16e-05	196	123	8	1819_DN
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	BICRA CAMK2G UBAP1 SRCAP MICAL2 SUPT6H KAT6B NFAT5	1.16e-05	196	123	8	2974_DN
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	NACA POU2F1 TSC22D2 ZBTB40 NFAT5 PCDH9 ZNF292	2.88e-05	162	123	7	7340_UP
Drug	Digitoxigenin [143-62-4]; Up 200; 10.6uM; HL60; HT_HG-U133A	NACA UBAP1 POU2F1 TSC22D2 MTF1 ZBTB40 NFAT5	2.88e-05	162	123	7	1339_UP
Drug	Digitoxigenin [143-62-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A	NACA TSC22D2 OVGP1 ZBTB40 PXN NFAT5 PCDH9	3.24e-05	165	123	7	3275_UP
Drug	Helveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A	KDM3A NACA POU2F1 ZBTB40 NFAT5 PCDH9 ZNF292	3.50e-05	167	123	7	6047_UP
Disease	pulse pressure measurement	SLAIN2 HDAC9 FN1 RAPH1 UBAP1 NBEA ZBTB41 TSC22D2 SRCAP ZNF831 CASZ1 ARID1B ZFHX4 MTF1 YAP1 SUPT6H NFAT5 NPAS2	1.35e-05	1392	120	18	EFO_0005763
Disease	vital capacity	HDAC9 NCOA6 FN1 CAMK2G PCLO MFSD6 CASZ1 CRYBA1 GABPB2 MTF1 SUSD5 RTL9 CAPRIN2 ZBTB40 NFAT5 TNXB	4.20e-05	1236	120	16	EFO_0004312
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	CAMK2G MED13 ZNF292	4.28e-05	17	120	3	DOID:0060307 (is_implicated_in)
Disease	depressive symptom measurement	SOX5 HDAC9 PCLO ITIH4 PTPRG PAX6 TNXB SDK1 PCDH9	6.38e-05	426	120	9	EFO_0007006
Disease	Autistic Disorder	ZMYND11 NBEA CHD4 MTF1 PAX6 ZNF292 NPAS2	9.94e-05	261	120	7	C0004352
Disease	Malignant neoplasm of breast	KDM3A NCOA6 FN1 RAPH1 POU2F1 WNK1 ARID1B KMT2D SEMA5B SBNO1 YAP1 KAT6B VPS13B TP73	1.22e-04	1074	120	14	C0006142
Disease	atrial fibrillation	SOX5 KDM3A BICRA NACA CASZ1 ZFHX4 IL6R ZNF292	1.43e-04	371	120	8	EFO_0000275
Disease	Alveolar rhabdomyosarcoma	WWTR1 TP73	1.63e-04	5	120	2	C0206655
Disease	Epithelioid hemangioendothelioma	WWTR1 YAP1	1.63e-04	5	120	2	C0206732
Disease	hepatocellular carcinoma (is_marker_for)	KDM3A CHD4 APOC2 ITIH4 ARID2 TP73 RAD21	2.39e-04	301	120	7	DOID:684 (is_marker_for)
Disease	Schizophrenia	SOX5 HDAC9 CHD4 CHRM1 SBNO1 TMEM245 CSPG5 PAX6 DNM1 TNXB IL6R NPAS2	2.62e-04	883	120	12	C0036341
Disease	platelet component distribution width	HDAC9 NPEPPS ZNF831 WNK1 TLX1 KIF9 MTF1 PRRC2C DNM1 TNXB NPAS2	2.65e-04	755	120	11	EFO_0007984
Disease	stomach cancer (is_marker_for)	ZMYND11 NBEA KMT2D TP73 EPHB1	2.94e-04	142	120	5	DOID:10534 (is_marker_for)
Disease	autism spectrum disorder (implicated_via_orthology)	NBEA MEF2A MEF2D ARID1B SH3RF2	4.02e-04	152	120	5	DOID:0060041 (implicated_via_orthology)
Disease	X-linked infantile spasms	CAMK2G DNM1	4.52e-04	8	120	2	C4552072
Disease	glucose intolerance (is_implicated_in)	PAX6 NEUROG3	4.52e-04	8	120	2	DOID:10603 (is_implicated_in)
Disease	ovarian cancer (implicated_via_orthology)	WWTR1 YAP1	4.52e-04	8	120	2	DOID:2394 (implicated_via_orthology)
Disease	cataract (implicated_via_orthology)	CRYBA1 PAX6 VPS13B	4.99e-04	38	120	3	DOID:83 (implicated_via_orthology)
Disease	heart disease (implicated_via_orthology)	SOX5 WWTR1 YAP1	4.99e-04	38	120	3	DOID:114 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	SRCAP ARID1B DNM1 ZNF292	5.75e-04	93	120	4	C1535926
Disease	Antihypertensive use measurement	HDAC9 MFSD6 NACA ZNF831 CASZ1 NFAT5	7.71e-04	265	120	6	EFO_0009927
Disease	spontaneous preterm birth	HDAC9 NHSL1 PTPRG SDK1	7.84e-04	101	120	4	EFO_0006917
Disease	urinary albumin to creatinine ratio	RAPH1 ZNF362 CASZ1 PRRC2C MGA	8.43e-04	179	120	5	EFO_0007778
Disease	alkaline phosphatase measurement	UBAP1 PAPLN ITIH4 GORASP2 KIF9 BAIAP2L1 YAP1 MITF ZBTB40 PPP1R37 NFAT5 IL6R	8.99e-04	1015	120	12	EFO_0004533
Disease	Dupuytren Contracture	PTPRG ZBTB40 PXN SDK1	1.01e-03	108	120	4	EFO_0004229
Disease	collagen disease (implicated_via_orthology)	COL4A6 DNM1	1.05e-03	12	120	2	DOID:854 (implicated_via_orthology)
Disease	sitting height ratio	CRYBA1 ARID1B EPHB1	1.18e-03	51	120	3	EFO_0007118
Disease	diet measurement	SOX5 HDAC9 NCOA6 ZMYND11 MFSD6 UBAP1 KHDC4 ARID1B MUC17 ARID2 SIK2 SDK1	1.19e-03	1049	120	12	EFO_0008111
Disease	neuroticism measurement	SOX5 AFF2 PCLO ITIH4 PTPRG MICAL2 PAX6 TNXB SDK1 PCDH9 EPHB1	1.23e-03	909	120	11	EFO_0007660
Disease	Coffin-Siris syndrome	ARID1B ARID2	1.24e-03	13	120	2	C0265338
Disease	plasminogen activator inhibitor 1 measurement	UBAP1 MUC17 MITF	1.40e-03	54	120	3	EFO_0004792
Disease	obesity (implicated_via_orthology)	KDM3A GORASP2 ZFHX4 SDK1 MED13	1.90e-03	215	120	5	DOID:9970 (implicated_via_orthology)
Disease	Schizoaffective disorder-bipolar type	PCLO RAD21	1.90e-03	16	120	2	EFO_0009965
Disease	T-Cell Lymphoma	KMT2D MGA	1.90e-03	16	120	2	C0079772
Disease	response to acetylsalicylate	KIF9 EPHB1	1.90e-03	16	120	2	GO_1903492
Disease	testosterone measurement	SOX5 NCOA6 NPEPPS UBAP1 TSC22D2 SRCAP CRYBA1 ARID1B ZFHX4 PTPRG BAIAP2L1 YAP1 RTL9	2.08e-03	1275	120	13	EFO_0004908
Disease	bacteriemia	PTPRG SH3RF2	2.14e-03	17	120	2	EFO_0003033
Disease	oral squamous cell carcinoma (is_marker_for)	KMT2D ARID2 RAD21	2.18e-03	63	120	3	DOID:0050866 (is_marker_for)
Disease	bilirubin measurement	SOX5 BAIAP2L1 MTF1 SIK2 IL6R NPAS2 EPHB1	2.25e-03	442	120	7	EFO_0004570
Disease	carcinoma (implicated_via_orthology)	WWTR1 LATS1 YAP1	2.28e-03	64	120	3	DOID:305 (implicated_via_orthology)
Disease	susceptibility to cold sores measurement	MUC16 MICAL2 TNXB	2.38e-03	65	120	3	EFO_0008402
Disease	Intellectual Disability	ZMYND11 NBEA MTF1 ZBTB40 PAX6 MED13 ZNF292	2.40e-03	447	120	7	C3714756
Disease	inflammatory bowel disease	SOX5 SLAIN2 HDAC9 CAMK2G ZNF831 ZBTB40 TNXB	2.46e-03	449	120	7	EFO_0003767
Disease	lung non-small cell carcinoma (is_implicated_in)	ARID1B KMT2D TP73 RAD21	2.54e-03	139	120	4	DOID:3908 (is_implicated_in)
Disease	Neoplastic Cell Transformation	FN1 TLX1 MITF PXN	2.54e-03	139	120	4	C0007621
Disease	stroke, major depressive disorder	SOX5 PTPRG	2.68e-03	19	120	2	EFO_0000712, MONDO_0002009
Disease	stroke	HDAC9 CASZ1 PTPRG MICAL2	2.88e-03	144	120	4	EFO_0000712
Disease	lung cancer (is_implicated_in)	NCOA6 CHD4 TP73	3.45e-03	74	120	3	DOID:1324 (is_implicated_in)
Disease	JT interval	NACA CASZ1 ARID2 MITF PXN	3.51e-03	248	120	5	EFO_0007885
Disease	intellectual disability (implicated_via_orthology)	MEF2A MEF2D RBFOX2	3.58e-03	75	120	3	DOID:1059 (implicated_via_orthology)
Disease	C-reactive protein measurement	SOX5 RPGRIP1 NCOA6 CAMK2G APOC2 LATS1 SBNO1 ZBTB40 PPP1R37 PXN NFAT5 IL6R	3.76e-03	1206	120	12	EFO_0004458
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KMT2D MITF	3.92e-03	23	120	2	C1708353

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDPDMVTSTQVPPTA	PTPRG	666	P23470
QSMFEPPQVSSPVQE	AKAP2	621	Q9Y2D5
STTAPIPMMPVSQTQ	COL4A6	1546	Q14031
PQPEVSVTSTMPNVA	ELK1	101	P19419
PQQDEMPSPTFLTQV	APOC2	26	P02655
QSIMPPAIPEATEAS	CSPG5	136	O95196
TVPEPVMSTPITEEQ	C2orf78	861	A6NCI8
QLASTIPQMPQIPAS	CASZ1	1121	Q86V15
ISNEEPTFSPIPVMQ	AFF2	771	P51816
PVPATNNQVPTAMSS	ARID2	976	Q68CP9
MSAVSQPQAAPSPLE	ABLIM2	1	Q6H8Q1
QKVMPTVPTSQVTGP	ARID1B	1651	Q8NFD5
SLVMPPSTQAVSFQP	CDAN1	421	Q8IWY9
IEETTMTTQTPAPIQ	ITIH4	716	Q14624
MTTQTPAPIQAPSAI	ITIH4	721	Q14624
VPTVPTVEAMQVPAA	RBM42	66	Q9BTD8
QPTMATVVPQVPTSP	RAPH1	1141	Q70E73
EPTQTPPTMTERETQ	RAB44	551	Q7Z6P3
PMPTMTDQTTLVPNE	RAD21	286	O60216
NQEPTTTPDAMVQPF	RBFOX2	21	O43251
NDNPPEVMVSSVSSP	PCDHB1	341	Q9Y5F3
PIPENSSPEMVVAVF	PCDHB18P	301	Q96TA0
TPPMQLAEIPETSNA	KAT6B	1776	Q8WYB5
PQTVLQSTPAPMAQF	NPAS2	481	Q99743
VSVPVQVPGSEPDMS	PAX6	401	P26367
NITTNQAAPSTVPIM	EPHB1	426	P54762
TPETTVPMETTVEPV	MUC16	3231	Q8WXI7
FPTITVSPDVPDMVT	MUC16	11391	Q8WXI7
PEVTMSAFTSPIPEN	PCDHB13	346	Q9Y5F0
EQMTSPAPPRIITSA	ESPNL	386	Q6ZVH7
TMTVQVSGNPPPEVI	MYLK	641	Q15746
VNQSLTSVPPMNPAT	GORASP2	286	Q9H8Y8
MTPQPSGAPTVQVTR	NEUROG3	1	Q9Y4Z2
TPQVFLENTTAVTPM	MGA	1601	Q8IWI9
TASNVTVMPPVAEAP	LATS1	536	O95835
NTTTVSTPMPPPVDD	DNM1	746	Q05193
SPSRVEANVPMVQPD	NHSL1	1276	Q5SYE7
VATMSFTPQVQPTPT	PCLO	3931	Q9Y6V0
MFPSPVINISIPENT	PCDH9	141	Q9HC56
MDVNDNSPVVISPPS	PCDH9	666	Q9HC56
VVPVSDPPVNSQQMV	MPP4	231	Q96JB8
PSVTPMTIVENPQGV	KIF9	161	Q9HAQ2
MVRTQTESSTPPGIP	PDPK2P	1	Q6A1A2
PPQNFSMSVTVPVTS	MEF2A	136	Q02078
TVTLPTAPNMNSEPT	MFSD6	211	Q6ZSS7
PMDTTISINNTVITP	OR4D6	266	Q8NGJ1
PVTTLLSQQMPENSP	NFAT5	1486	O94916
SAATPMTQIPLSQPI	POU2F1	156	P14859
QPPQLSASMPETTAT	PPP1R37	466	O75864
PVPAITVNQGEMSSP	PXN	231	P49023
EVSSNVAPSIPPVMS	NCOA6	1566	Q14686
QPSSTFDTMSPAPVI	TP73	101	O15350
LQLPTPPEVMSEQSV	PIKFYVE	1576	Q9Y2I7
PPAENEVSTPMQALT	IL6R	321	P08887
EASPSMCPVQSVPTT	KDM3A	281	Q9Y4C1
STPVSGTPQASPMIE	BAIAP2L1	251	Q9UHR4
PSQPLESSMVVTPVN	CABIN1	306	Q9Y6J0
ESSMVVTPVNVIQPS	CABIN1	311	Q9Y6J0
MVQPQSPVAVSQSKP	FN1	36	P02751
SMQPPSEAPMVNTVS	C19orf44	451	Q9H6X5
VRVQDGPSQTQPTMT	GAS2L2	296	Q8NHY3
ETLPTTKMAQTNPTP	CRYBA1	11	P05813
MNTSAPPAVSPNITV	CHRM1	1	P11229
DSRSMTPVDVPVTNP	CAPRIN2	966	Q6IMN6
ITQVQPPASTGQSPM	KHDC4	411	Q7Z7F0
PDTTREIVMTQSPPT	IGKV3-7	16	A0A075B6H7
TSVLPPTPHAEQMVS	HDAC9	291	Q9UKV0
VTLPPSAVAMLNTPD	BICRA	586	Q9NZM4
VVESMVTATEVAPPP	CHD4	236	Q14839
PTTAQVMIEAQPPKV	PSG11	31	Q9UQ72
VMQNVQPPKSSPVVS	SEC24B	301	O95487
TTAMSNTPGTPVTPV	SCAF8	151	Q9UPN6
VVTTQAEVFPPPVAM	SCAF8	626	Q9UPN6
PAMAPQNVQVTPLTA	SDK1	1701	Q7Z5N4
PMPTPSVQQSVPLSA	SBNO1	36	A3KN83
SSPTEQVPSQEMPLL	PPRC1	841	Q5VV67
MVPITISTSEDPNQA	NPEPPS	541	P55786
VSPAQEPAPLQTAME	CAMK2G	351	Q13555
EPAPLQTAMEPQTTV	CAMK2G	356	Q13555
AMPVTVPVSNQSSLQ	MEF2D	141	Q14814
SSPPQMTASEPLSQV	MICAL2	1301	O94851
MLSSSPVIQLPEQTP	OVGP1	621	Q12889
PEVTMSAFTSPIPEN	PCDHB8	346	Q9UN66
MTPLTSVPVSNTPVA	MUC17	3221	Q685J3
STPLTNMPVSTTPVA	MUC17	3516	Q685J3
QVSSSPVTPEGTTMP	MUC17	3671	Q685J3
VNPERANPVTDPVSM	GABPB2	166	Q8TAK5
VPAPSSEAMSPLQIT	RTL9	221	Q8NET4
TPNHIPSTIMATTQP	SUSD5	506	O60279
PSTIMATTQPPVETT	SUSD5	511	O60279
PSVEMETQNATTIPP	TEX55	406	Q96M34
SFPSQDQMASPEVPI	RPGRIP1	961	Q96KN7
VDLTPVVPSAVNMNP	PPP1R8	301	Q12972
QTTSSPGPPMVQSTV	SLAIN2	496	Q9P270
VSTTSVTMPNVPAPL	TSC22D2	521	O75157
TASMVSVLPQDPTQP	SCRN2	286	Q96FV2
PPQSTTEPLPAMVQT	MTF1	521	Q14872
TSKNLPAVQTVAPMP	NBEA	1861	Q8NFP9
MPQIPVASVTPTASL	PRRC2C	2301	Q9Y520
TQPLSPVLEPSSEQM	SIK2	771	Q9H0K1
TVQHDSVPMTAVPPF	SHISA2	251	Q6UWI4
APTSQSLITPPQMTN	MED13	1481	Q9UHV7
VLASSQTPVPVMAPS	SRCAP	1621	Q6ZRS2
IPDPTTTPQPFTTMQ	SSC5D	1256	A1L4H1
TPAQQPVATPLMTPS	SUPT6H	1606	Q7KZ85
PPNVTSLIQPMSQGV	TIGD2	316	Q4W5G0
SQTPVPSSPLQISMT	ZFHX4	2421	Q86UP3
TVTPPNFSVSQVPNM	UBAP1	361	Q9NZ09
SVPTTLPSATQVPME	MITF	101	O75030
PQEVPSMQDVHTPAS	PAPLN	541	O95428
VETVPNTPQISPAMA	SAGE1	806	Q9NXZ1
PVTAMSSVETPQISP	SAGE2P	511	A6NJ88
TLVPVQMPDTPSDLV	ZBTB41	811	Q5SVQ8
EAETTQAVPTMTPEP	TNXB	2611	P22105
SQVNATVMPNPTVPP	ZNF292	1521	O60281
AVMNPKTANVPQTVP	YAP1	71	P46937
TPMQIIQPTTSEDPN	USF3	686	Q68DE3
MSEAVQPVTPEPCVT	SEMA5B	451	Q9P283
PAVPPNTDVMACTQT	ZNRD2	141	O60232
TVPSVPAMPGVNNLT	TLX1	156	P31314
SAMLVSPTNSVPTPN	TMEM245	841	Q9H330
EAVSSSQEIPTMPQP	ZMYND11	416	Q15326
SQEIPTMPQPIEKVS	ZMYND11	421	Q15326
AVTPTPVPVVGSQMT	U2AF2	131	P26368
VSEPVPQMSSPVEKN	VPS13B	2276	Q7Z7G8
VPPAPAESSQAVMSL	ZNF362	71	Q5T0B9
PQGIPSSPSAVVVEM	SH3RF2	556	Q8TEC5
SSVSSSPEPGMPVIQ	SOX5	696	P35711
IPASSMPQQIGIPTS	WNK1	1231	Q9H4A3
STPPPASVINNMLAE	ZBED1	536	O96006
TVPGVMPQHQVSEPE	ZNF831	1251	Q5JPB2
IPMISPSPSQEELQT	ABI3BP	606	Q7Z7G0
SQMAQVIQTPEPVAP	ZBTB40	1171	Q9NUA8
TLAPVQAAVNPPTMT	WWTR1	271	Q9GZV5
PPSVQQKMVNGVTPS	KMT2D	4631	O14686
LPQPQAETAVLPMSS	NACA	16	E9PAV3
PLVAQMPVSSVGTTP	NACA	426	E9PAV3
PISNIEPTSPAALVM	NACA	471	E9PAV3