Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mRNA processing	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	1.18e-10	551	37	12	GO:0006397
GeneOntologyBiologicalProcess	mRNA metabolic process	RBM42 SMN1 RBM25 TAF3 SF3B4 TAF1 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	2.51e-10	917	37	14	GO:0016071
GeneOntologyBiologicalProcess	spliceosomal complex assembly	SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	4.33e-10	99	37	7	GO:0000245
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	RBM42 SMN1 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	5.03e-10	358	37	10	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	RBM42 SMN1 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	5.03e-10	358	37	10	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	RBM42 SMN1 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	5.60e-10	362	37	10	GO:0000375
GeneOntologyBiologicalProcess	RNA splicing	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	7.68e-10	502	37	11	GO:0008380
GeneOntologyBiologicalProcess	actin nucleation	DIAPH1 FMN2 MAGEL2 INF2 FMN1	1.07e-07	65	37	5	GO:0045010
GeneOntologyBiologicalProcess	protein-RNA complex assembly	SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	2.26e-07	244	37	7	GO:0022618
GeneOntologyBiologicalProcess	protein-RNA complex organization	SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	2.97e-07	254	37	7	GO:0071826
GeneOntologyBiologicalProcess	regulation of RNA splicing	RBM42 SMN1 RBM25 SF3B4 PUF60 SF1	1.70e-06	207	37	6	GO:0043484
GeneOntologyBiologicalProcess	mRNA splice site recognition	SNRPC PUF60 SF3A2 SF1	2.23e-06	52	37	4	GO:0006376
GeneOntologyBiologicalProcess	ultradian rhythm	ENOX1 ENOX2	3.13e-06	2	37	2	GO:0007624
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	RBM42 RBM25 SF3B4 PUF60 SF1	3.29e-06	129	37	5	GO:0048024
GeneOntologyBiologicalProcess	RNA processing	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	7.00e-06	1500	37	12	GO:0006396
GeneOntologyBiologicalProcess	regulation of mRNA processing	RBM42 RBM25 SF3B4 PUF60 SF1	8.85e-06	158	37	5	GO:0050684
GeneOntologyBiologicalProcess	U2-type prespliceosome assembly	SF3B4 SF3A2 SF3B2	1.19e-05	25	37	3	GO:1903241
GeneOntologyBiologicalProcess	ribonucleoprotein complex biogenesis	SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	3.12e-05	515	37	7	GO:0022613
GeneOntologyBiologicalProcess	mRNA 3'-splice site recognition	SF3A2 SF1	6.54e-05	7	37	2	GO:0000389
GeneOntologyBiologicalProcess	Leydig cell differentiation	NR5A1 SF1	2.41e-04	13	37	2	GO:0033327
GeneOntologyBiologicalProcess	positive regulation of actin nucleation	MAGEL2 FMN1	2.81e-04	14	37	2	GO:0051127
GeneOntologyBiologicalProcess	male sex determination	NR5A1 SF1	3.70e-04	16	37	2	GO:0030238
GeneOntologyBiologicalProcess	rhythmic process	TYRO3 NR5A1 MAGEL2 ENOX1 ENOX2	4.34e-04	360	37	5	GO:0048511
GeneOntologyBiologicalProcess	maintenance of protein location in nucleus	NR5A1 TAF3	9.90e-04	26	37	2	GO:0051457
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	RBM42 RBM25 SF3B4 PUF60 SF1	1.11e-03	443	37	5	GO:1903311
GeneOntologyBiologicalProcess	supramolecular fiber organization	DIAPH1 FMN2 ZNF207 SMN1 MAGEL2 INF2 FMN1	1.37e-03	957	37	7	GO:0097435
GeneOntologyBiologicalProcess	sex determination	NR5A1 SF1	1.41e-03	31	37	2	GO:0007530
GeneOntologyCellularComponent	Sm-like protein family complex	RBM42 SMN1 SF3B4 SNRPC SNRPN SF3A2 SF3B2	1.45e-09	119	37	7	GO:0120114
GeneOntologyCellularComponent	spliceosomal snRNP complex	RBM42 SF3B4 SNRPC SNRPN SF3A2 SF3B2	1.66e-08	96	37	6	GO:0097525
GeneOntologyCellularComponent	small nuclear ribonucleoprotein complex	RBM42 SF3B4 SNRPC SNRPN SF3A2 SF3B2	3.19e-08	107	37	6	GO:0030532
GeneOntologyCellularComponent	U2 snRNP	SF3B4 SNRPN SF3A2 SF3B2	1.65e-07	28	37	4	GO:0005686
GeneOntologyCellularComponent	nuclear protein-containing complex	RBM42 SMARCC2 NR5A1 TAF3 SF3B4 BCL11B TAF1 SNRPC SNRPN SF3A2 SF1 SF3B2 CPSF7	3.33e-07	1377	37	13	GO:0140513
GeneOntologyCellularComponent	U2-type spliceosomal complex	SF3B4 SNRPC SNRPN SF3A2 SF3B2	7.51e-07	97	37	5	GO:0005684
GeneOntologyCellularComponent	spliceosomal complex	SF3B4 SNRPC SNRPN SF3A2 SF1 SF3B2	1.97e-06	215	37	6	GO:0005681
GeneOntologyCellularComponent	U2-type prespliceosome	SNRPC SNRPN SF3A2	4.09e-06	18	37	3	GO:0071004
GeneOntologyCellularComponent	prespliceosome	SNRPC SNRPN SF3A2	4.09e-06	18	37	3	GO:0071010
GeneOntologyCellularComponent	U2-type precatalytic spliceosome	SF3B4 SF3A2 SF3B2	1.00e-04	51	37	3	GO:0071005
GeneOntologyCellularComponent	precatalytic spliceosome	SF3B4 SF3A2 SF3B2	1.19e-04	54	37	3	GO:0071011
GeneOntologyCellularComponent	actin filament	DIAPH1 FMN2 INF2 FMN1	1.26e-04	146	37	4	GO:0005884
GeneOntologyCellularComponent	nuclear body	ESX1 SMN1 RBM25 TCERG1 SNRPC SF3A2 SF1 SF3B2	1.49e-04	903	37	8	GO:0016604
GeneOntologyCellularComponent	catalytic step 2 spliceosome	SNRPN SF3A2 SF3B2	6.71e-04	97	37	3	GO:0071013
GeneOntologyCellularComponent	nuclear speck	ESX1 RBM25 TCERG1 SF3A2 SF3B2	9.21e-04	431	37	5	GO:0016607
GeneOntologyCellularComponent	ribonucleoprotein complex	RBM42 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	9.67e-04	1194	37	8	GO:1990904
GeneOntologyCellularComponent	SWI/SNF complex	SMARCC2 BCL11B	1.29e-03	30	37	2	GO:0016514
GeneOntologyCellularComponent	U12-type spliceosomal complex	SF3B4 SF3B2	1.29e-03	30	37	2	GO:0005689
GeneOntologyCellularComponent	U1 snRNP	SNRPC SNRPN	1.55e-03	33	37	2	GO:0005685
GeneOntologyCellularComponent	transcription factor TFIID complex	TAF3 TAF1	3.13e-03	47	37	2	GO:0005669
GeneOntologyCellularComponent	U4/U6 x U5 tri-snRNP complex	RBM42 SNRPN	3.13e-03	47	37	2	GO:0046540
GeneOntologyCellularComponent	spliceosomal tri-snRNP complex	RBM42 SNRPN	3.27e-03	48	37	2	GO:0097526
GeneOntologyCellularComponent	actin cytoskeleton	DIAPH1 FMN2 INF2 FMN1 ARHGAP33	3.28e-03	576	37	5	GO:0015629
HumanPheno	Skin tags	FGD1 SF3B4 PUF60 SNRPN SF3B2	8.35e-06	97	16	5	HP:0010609
HumanPheno	Cervical ribs	SF3B4 PUF60 SF3B2	9.06e-06	14	16	3	HP:0000891
HumanPheno	Abnormal periauricular region morphology	FGD1 SF3B4 PUF60 SNRPN SF3B2	3.62e-05	131	16	5	HP:0000383
HumanPheno	Short 5th finger	FGD1 SMARCC2 SF3B4 PUF60	3.68e-05	64	16	4	HP:0009237
HumanPheno	Aplasia/Hypoplasia of the 5th finger	FGD1 SMARCC2 SF3B4 PUF60	4.16e-05	66	16	4	HP:0006262
HumanPheno	Hemifacial hypoplasia	PUF60 SF3B2	5.53e-05	4	16	2	HP:0011332
HumanPheno	Supernumerary ribs	SF3B4 PUF60 SF3B2	7.94e-05	28	16	3	HP:0005815
HumanPheno	Supernumerary bones of the axial skeleton	SF3B4 PUF60 SF3B2	8.84e-05	29	16	3	HP:0009144
HumanPheno	Abnormal maxilla morphology	FGD1 SF3B4 SOBP SNRPN SF3B2	8.92e-05	158	16	5	HP:0000326
HumanPheno	Postterm pregnancy	MAGEL2 SNRPN	9.20e-05	5	16	2	HP:0031169
HumanPheno	Occipital cortical atrophy	MAGEL2 SNRPN	9.20e-05	5	16	2	HP:0012105
HumanPheno	Preauricular skin tag	FGD1 SF3B4 SNRPN SF3B2	9.34e-05	81	16	4	HP:0000384
HumanPheno	Periauricular skin tag	FGD1 SF3B4 SNRPN SF3B2	9.34e-05	81	16	4	HP:0100278
HumanPheno	Intellectual disability, moderate	SMARCC2 MAGEL2 TAF1 PUF60 SNRPN	1.34e-04	172	16	5	HP:0002342
HumanPheno	Abnormal circulating inhibin level	MAGEL2 SNRPN	1.38e-04	6	16	2	HP:0031099
HumanPheno	Bulimia	MAGEL2 SNRPN	1.38e-04	6	16	2	HP:0100739
HumanPheno	Decreased circulating inhibin B concentration	MAGEL2 SNRPN	1.38e-04	6	16	2	HP:0031100
HumanPheno	Abnormal circulating inhibin B concentration	MAGEL2 SNRPN	1.38e-04	6	16	2	HP:0430147
HumanPheno	Abnormality of temperature sensation	ZFHX2 MAGEL2 SNRPN	1.43e-04	34	16	3	HP:0100772
HumanPheno	Impaired temperature sensation	ZFHX2 MAGEL2 SNRPN	1.43e-04	34	16	3	HP:0010829
HumanPheno	Hypermetropia	FGD1 MAGEL2 BCL11B PUF60 SOBP SNRPN	1.53e-04	288	16	6	HP:0000540
HumanPheno	Parietal cortical atrophy	MAGEL2 SNRPN	2.56e-04	8	16	2	HP:0012104
HumanPheno	Delayed puberty	DIAPH1 FGD1 NR5A1 MAGEL2 SNRPN	3.57e-04	212	16	5	HP:0000823
HumanPheno	Thin upper lip vermilion	SMARCC2 MAGEL2 BCL11B TAF1 PUF60 SNRPN	3.76e-04	339	16	6	HP:0000219
HumanPheno	Thin lips	SMARCC2 MAGEL2 BCL11B TAF1 PUF60 SNRPN	3.76e-04	339	16	6	HP:0000213
HumanPheno	Abnormal ulnar metaphysis morphology	MAGEL2 SNRPN	4.10e-04	10	16	2	HP:0004039
HumanPheno	Premature adrenarche	MAGEL2 SNRPN	4.10e-04	10	16	2	HP:0012412
HumanPheno	Abnormal circulating gonadotropin concentration	FGD1 NR5A1 MAGEL2 SNRPN	5.48e-04	128	16	4	HP:0030338
HumanPheno	Toe deformity	SF3B4 INF2 PUF60 SNRPN	5.64e-04	129	16	4	HP:0034398
HumanPheno	Hypoplasia of the maxilla	FGD1 SF3B4 SNRPN SF3B2	5.81e-04	130	16	4	HP:0000327
HumanPheno	Skin-picking	MAGEL2 SNRPN	5.99e-04	12	16	2	HP:0012166
HumanPheno	Abnormality of refraction	FGD1 SMARCC2 MAGEL2 BCL11B TAF1 PUF60 SOBP SNRPN	6.20e-04	709	16	8	HP:0000539
HumanPheno	Aplasia/Hypoplasia of the maxilla	FGD1 SF3B4 SNRPN SF3B2	6.33e-04	133	16	4	HP:0009117
HumanPheno	Premature pubarche	MAGEL2 SNRPN	7.07e-04	13	16	2	HP:0012411
HumanPheno	Almond-shaped palpebral fissure	MAGEL2 PUF60 SNRPN	7.43e-04	59	16	3	HP:0007874
HumanPheno	Abnormal scrotum morphology	FGD1 NR5A1 MAGEL2 SNRPN	8.33e-04	143	16	4	HP:0000045
HumanPheno	Abnormal shape of the palpebral fissure	MAGEL2 PUF60 SNRPN	9.86e-04	65	16	3	HP:0200005
HumanPheno	Small scrotum	NR5A1 MAGEL2 SNRPN	1.03e-03	66	16	3	HP:0000046
HumanPheno	Abnormal upper lip morphology	FGD1 SMARCC2 SF3B4 MAGEL2 BCL11B TAF1 PUF60 SNRPN SF3B2	1.08e-03	980	16	9	HP:0000177
HumanPheno	Thick eyebrow	SMARCC2 MAGEL2 TAF1 PUF60	1.10e-03	154	16	4	HP:0000574
HumanPheno	Broad nasal tip	SMARCC2 TAF1 PUF60 SNRPN	1.24e-03	159	16	4	HP:0000455
HumanPheno	Abnormal cheek morphology	FGD1 SF3B4 PUF60 SNRPN SF3B2	1.32e-03	282	16	5	HP:0004426
HumanPheno	Overlapping toe	SF3B4 PUF60 SNRPN	1.33e-03	72	16	3	HP:0001845
HumanPheno	Vertebral segmentation defect	FGD1 TAF1 PUF60 SF3B2	1.33e-03	162	16	4	HP:0003422
HumanPheno	Central adrenal insufficiency	MAGEL2 SNRPN	1.37e-03	18	16	2	HP:0011734
HumanPheno	Abnormal upper limb metaphysis morphology	MAGEL2 SNRPN	1.37e-03	18	16	2	HP:0009809
HumanPheno	Thin vermilion border	SMARCC2 MAGEL2 BCL11B TAF1 PUF60 SNRPN	1.39e-03	433	16	6	HP:0000233
Domain	FH2	DIAPH1 FMN2 INF2 FMN1	1.75e-08	15	37	4	PS51444
Domain	FH2_Formin	DIAPH1 FMN2 INF2 FMN1	1.75e-08	15	37	4	IPR015425
Domain	FH2	DIAPH1 FMN2 INF2 FMN1	1.75e-08	15	37	4	PF02181
Domain	FH2	DIAPH1 FMN2 INF2 FMN1	1.75e-08	15	37	4	SM00498
Domain	RRM_1	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	1.49e-07	208	37	7	PF00076
Domain	RRM	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	1.99e-07	217	37	7	SM00360
Domain	RRM_dom	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	2.70e-07	227	37	7	IPR000504
Domain	RRM	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	2.95e-07	230	37	7	PS50102
Domain	-	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	4.39e-07	244	37	7	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	6.39e-07	258	37	7	IPR012677
Domain	Drf_FH1	DIAPH1 FMN2	3.82e-06	2	37	2	PF06346
Domain	Formin_homology_1	DIAPH1 FMN2	3.82e-06	2	37	2	IPR009408
Domain	ZnF_U1	ZFHX2 SNRPC SF3A2	2.52e-05	29	37	3	SM00451
Domain	Znf_U1	ZFHX2 SNRPC SF3A2	2.52e-05	29	37	3	IPR003604
Domain	Drf_GBD	DIAPH1 INF2	1.36e-04	9	37	2	PF06371
Domain	FH3_dom	DIAPH1 INF2	1.36e-04	9	37	2	IPR010472
Domain	GTPase-bd	DIAPH1 INF2	1.36e-04	9	37	2	IPR010473
Domain	Drf_FH3	DIAPH1 INF2	1.36e-04	9	37	2	PF06367
Domain	Drf_FH3	DIAPH1 INF2	1.36e-04	9	37	2	SM01139
Domain	Drf_GBD	DIAPH1 INF2	1.36e-04	9	37	2	SM01140
Domain	GBD/FH3_dom	DIAPH1 INF2	2.08e-04	11	37	2	IPR014768
Domain	GBD_FH3	DIAPH1 INF2	2.08e-04	11	37	2	PS51232
Domain	Znf_C2H2_matrin	SNRPC SF3A2	2.49e-04	12	37	2	IPR000690
Domain	ZF_MATRIN	SNRPC SF3A2	5.73e-04	18	37	2	PS50171
Domain	-	FGD1 TAF3 TRIM50 ZNF598 DTX4	1.82e-03	449	37	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	FGD1 TAF3 TRIM50 ZNF598 DTX4	2.00e-03	459	37	5	IPR013083
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	RBM42 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	1.24e-11	277	32	11	MM15414
Pathway	REACTOME_MRNA_SPLICING	RBM42 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	1.36e-11	201	32	10	MM15411
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	RBM42 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	1.56e-11	283	32	11	M13087
Pathway	REACTOME_MRNA_SPLICING	RBM42 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	2.31e-11	212	32	10	M14033
Pathway	WP_MRNA_PROCESSING	RBM42 SMN1 RBM25 SF3B4 ENOX1 SNRPC PUF60 SNRPN SF3A2 SF3B2 CPSF7 ENOX2	1.26e-10	451	32	12	MM15946
Pathway	REACTOME_METABOLISM_OF_RNA	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	4.10e-09	612	32	12	MM15547
Pathway	KEGG_SPLICEOSOME	RBM25 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF3B2	1.14e-08	127	32	7	M2044
Pathway	REACTOME_METABOLISM_OF_RNA	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	2.69e-08	724	32	12	M16843
Pathway	WP_MRNA_PROCESSING	SF3B4 SNRPN SF3A2 SF3B2	1.80e-04	126	32	4	M39406
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	RBM42 ZNF207 SMN1 RBM25 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	8.24e-15	197	37	10	22365833
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	DIAPH1 SMARCC2 ZNF207 SF3B4 TCERG1 SF3A2 SF1 SF3B2 CPSF7	5.78e-14	154	37	9	16055720
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	DIAPH1 FMN2 SMARCC2 RBM25 SF3B4 TCERG1 INF2 PUF60 SF3A2 SF1 SF3B2 CPSF7	1.05e-13	506	37	12	30890647
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SMARCC2 ZNF207 RBM25 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2 CPSF7	2.58e-13	399	37	11	35987950
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	ZNF207 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2	3.98e-13	115	37	8	17332742
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM42 SMARCC2 ZNF207 RBM25 TAF3 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2 ARHGAP33 CPSF7	2.30e-12	1082	37	14	38697112
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SMARCC2 ZNF207 RBM25 TAF3 SF3B4 TAF1 TCERG1 SNRPC PUF60 SNRPN SF1 SF3B2 CPSF7	8.89e-12	954	37	13	36373674
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SMARCC2 SMN1 RBM25 SF3B4 TCERG1 PUF60 SNRPN SF3A2 SF1 SF3B2 CBFA2T2 CPSF7	4.27e-11	847	37	12	35850772
Pubmed	Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.	SF3B4 TCERG1 SF3A2 SF1 SF3B2	5.38e-11	25	37	5	9731529
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	SMARCC2 ZNF207 NR5A1 RBM25 SNRPN SF1 CPSF7	2.56e-10	153	37	7	28225217
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	ZNF207 RBM25 SF3B4 TCERG1 ZNF598 SNRPC PUF60 SF3A2 SF1 SF3B2 CPSF7	4.84e-10	807	37	11	22681889
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	SMN1 SF3B4 TCERG1 SNRPC	7.69e-10	13	37	4	17218272
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	DIAPH1 FMN2 INF2 FMN1	1.08e-09	14	37	4	26272686
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	RBM25 PUF60 SNRPN SF1 SF3B2 CPSF7	5.13e-09	130	37	6	35545047
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DIAPH1 SMARCC2 RBM25 TAF3 TAF1 TCERG1 PUF60 SF3A2 SF1 SF3B2 CPSF7	5.24e-09	1014	37	11	32416067
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RBM42 SMARCC2 ZNF207 SMN1 RBM25 TAF3 SF3B4 TCERG1 PUF60 SF1 SF3B2 CPSF7	9.96e-09	1371	37	12	36244648
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	SF3B4 TCERG1 SF1 SF3B2	1.35e-08	25	37	4	15456888
Pubmed	Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.	SF3B4 SF3A2 SF3B2	2.21e-08	6	37	3	10882114
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	SMARCC2 RBM25 SF3B4 SNRPC PUF60 SF3B2	2.56e-08	170	37	6	16159877
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	FGD1 SMARCC2 ZNF207 SMN1 RBM25 TCERG1 PUF60 SF3A2 SF1 ARHGAP33	2.80e-08	916	37	10	32203420
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	SMARCC2 RBM25 PUF60 SF3A2 SF1 SF3B2	3.60e-08	180	37	6	30110629
Pubmed	PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.	SMN1 SF3B4 SF3B2	3.87e-08	7	37	3	25737013
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DIAPH1 SMARCC2 RBM25 SF3B4 ZNF598 INF2 PUF60 SF3A2 SF1 SF3B2 CPSF7	4.37e-08	1247	37	11	27684187
Pubmed	Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.	SF3B4 PUF60 SF3A2 SF3B2	4.91e-08	34	37	4	12234937
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	RBM42 SMARCC2 SF3B4 SNRPC PUF60 SNRPN SF1 SF3B2 CPSF7	5.10e-08	723	37	9	34133714
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM42 ZNF207 RBM25 SF3B4 TCERG1 SNRPC SF3A2 SF1 SF3B2	5.60e-08	731	37	9	29298432
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	SF3B4 TCERG1 SF3A2 SF3B2 CPSF7	1.11e-07	109	37	5	12226669
Pubmed	A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.	SF3B4 SF3A2 SF3B2	1.32e-07	10	37	3	11500380
Pubmed	Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2.	SF3B4 SNRPN SF1	1.32e-07	10	37	3	15105431
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DIAPH1 SMARCC2 SMN1 SF3B4 PUF60 SF3A2 SF3B2 CPSF7	1.48e-07	582	37	8	20467437
Pubmed	The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.	TCERG1 FMN1 SF1	2.42e-07	12	37	3	11604498
Pubmed	Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli.	SMN1 SNRPC SNRPN	4.00e-07	14	37	3	10725331
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SMN1 RBM25 SF3B4 TCERG1 ZNF598 PUF60 SF3A2 SF1 SF3B2 CPSF7	5.25e-07	1257	37	10	36526897
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	RBM42 SF3B4 SNRPC SOBP SF1	5.81e-07	152	37	5	38360978
Pubmed	Structure of the human activated spliceosome in three conformational states.	SF3B4 SF3A2 SF3B2	6.15e-07	16	37	3	29360106
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM42 RBM25 SF3B4 TCERG1 SNRPC SNRPN SF3A2 SF1 SF3B2 CPSF7	6.83e-07	1294	37	10	30804502
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RBM42 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3B2 CPSF7	6.85e-07	713	37	8	29802200
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	SMARCC2 ZNF207 RBM25 TCERG1 SNRPN SF3A2 SF1 SF3B2 CPSF7	7.13e-07	989	37	9	36424410
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	DIAPH1 RBM25 TAF3 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2	8.08e-07	1318	37	10	30463901
Pubmed	Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.	TYRO3 NR5A1 SF1	1.06e-06	19	37	3	30212841
Pubmed	Coordination of microtubule acetylation and the actin cytoskeleton by formins.	FMN2 INF2	1.10e-06	2	37	2	29947928
Pubmed	Human immunodeficiency virus type 1 Vpr interacts with spliceosomal protein SAP145 to mediate cellular pre-mRNA splicing inhibition.	SF3B4 SF3B2	1.10e-06	2	37	2	17347016
Pubmed	The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site.	SF3B4 SF3B2	1.10e-06	2	37	2	7958871
Pubmed	Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145.	SF3B4 SF3B2	1.10e-06	2	37	2	16923959
Pubmed	Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment.	SF3B4 SF3B2	1.10e-06	2	37	2	27862552
Pubmed	The ability to induce microtubule acetylation is a general feature of formin proteins.	FMN2 FMN1	1.10e-06	2	37	2	23110170
Pubmed	Mechanisms of actin filament severing and elongation by formins.	DIAPH1 INF2	1.10e-06	2	37	2	38843827
Pubmed	SF-1 Induces Nuclear PIP2.	NR5A1 SF1	1.10e-06	2	37	2	37892191
Pubmed	An epigenetic circuit controls neurogenic programs during neocortex development.	SMARCC2 ZNF207 BCL11B	1.25e-06	20	37	3	35020876
Pubmed	Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.	SMARCC2 RBM25 SNRPC SF3A2 SF3B2	1.41e-06	182	37	5	26527279
Pubmed	Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.	SF3B4 SF3A2 SF3B2	1.45e-06	21	37	3	36797247
Pubmed	Molecular architecture of the human 17S U2 snRNP.	SF3B4 SF3A2 SF3B2	1.45e-06	21	37	3	32494006
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	SMARCC2 RBM25 TCERG1 ZNF598 SF3B2 CPSF7	1.50e-06	340	37	6	24332808
Pubmed	Structural and functional modularity of the U2 snRNP in pre-mRNA splicing.	SF3B4 SF3A2 SF3B2	2.21e-06	24	37	3	31744343
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	DIAPH1 SMN1 SF3B4 TCERG1 SNRPC PUF60 SF1 SF3B2 CPSF7	2.45e-06	1149	37	9	35446349
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	ZNF207 RBM25 SF3B4 PUF60 SF1 SF3B2 CPSF7	3.11e-06	607	37	7	39147351
Pubmed	Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC).	SF3B4 SF3B2	3.30e-06	3	37	2	25731616
Pubmed	Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features.	NR5A1 SF1	3.30e-06	3	37	2	38228887
Pubmed	Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules.	DIAPH1 INF2	3.30e-06	3	37	2	21998204
Pubmed	Mechanostress resistance involving formin homology proteins: G- and F-actin homeostasis-driven filament nucleation and helical polymerization-mediated actin polymer stabilization.	DIAPH1 FMN1	3.30e-06	3	37	2	30309655
Pubmed	Multilineage Pituitary Neuroendocrine Tumors (PitNETs) Expressing PIT1 and SF1.	NR5A1 SF1	3.30e-06	3	37	2	37268858
Pubmed	Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry.	SF3B4 SF3B2	3.30e-06	3	37	2	22415777
Pubmed	The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin gene.	MAGEL2 SNRPN	3.30e-06	3	37	2	15634360
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	SMARCC2 TAF3 TAF1 PUF60 SNRPN SF3B2	3.32e-06	390	37	6	17643375
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	DIAPH1 ZNF598 SF3A2 SF3B2 CPSF7	3.58e-06	220	37	5	24550385
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DIAPH1 SF3B4 TCERG1 PUF60 SNRPN SF3B2 CPSF7	4.32e-06	638	37	7	33239621
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	ZNF207 RBM25 SF3B4 TCERG1 SNRPC INF2 SF1	5.39e-06	660	37	7	32780723
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SMARCC2 SMN1 RBM25 SNRPC SF3B2	5.92e-06	244	37	5	29884807
Pubmed	Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.	SF3B4 SNRPC SF1 CPSF7	6.42e-06	113	37	4	23403292
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	RBM42 RBM25 SNRPC PUF60 SNRPN SF1 SF3B2	6.42e-06	678	37	7	30209976
Pubmed	Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain.	MAGEL2 SNRPN	6.60e-06	4	37	2	12971993
Pubmed	Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.	SF3A2 SF1	6.60e-06	4	37	2	15647371
Pubmed	Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.	PUF60 SF1	6.60e-06	4	37	2	18974054
Pubmed	Rpp20 interacts with SMN and is re-distributed into SMN granules in response to stress.	SMN1 SNRPN	6.60e-06	4	37	2	14715275
Pubmed	An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries.	SF1 CPSF7	6.60e-06	4	37	2	17024186
Pubmed	Characterization of a protein complex containing spliceosomal proteins SAPs 49, 130, 145, and 155.	SF3B4 SF3B2	6.60e-06	4	37	2	10490618
Pubmed	PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1.	NR5A1 SF1	6.60e-06	4	37	2	20133449
Pubmed	Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins.	FMN2 FMN1	6.60e-06	4	37	2	19605360
Pubmed	Determinants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1.	SMN1 SNRPN	6.60e-06	4	37	2	12244096
Pubmed	Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2).	DIAPH1 INF2	6.60e-06	4	37	2	21278336
Pubmed	A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.	SF3B4 PUF60 SF1 SF3B2 CPSF7	7.19e-06	254	37	5	28431233
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	RBM42 ZNF207 SF3B4 PUF60 SF3A2 SF1 CPSF7	8.20e-06	704	37	7	32994395
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2	8.99e-06	714	37	7	28302793
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	SMARCC2 RBM25 TCERG1 PUF60 SF3B2	9.84e-06	271	37	5	32433965
Pubmed	Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.	SF3B4 SF3B2	1.10e-05	5	37	2	27905398
Pubmed	Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex.	NR5A1 SF1	1.10e-05	5	37	2	16002533
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	SMARCC2 ZNF207 RBM25 SF3B4 PUF60 SF1	1.16e-05	486	37	6	30940648
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	SMARCC2 SF3B4 INF2 SNRPN SF3A2	1.17e-05	281	37	5	26725010
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TAF1 TCERG1 SNRPN SF1 SF3B2	1.21e-05	283	37	5	30585729
Pubmed	UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.	ZNF207 SMN1 PUF60 SNRPN SF3B2 CPSF7	1.23e-05	491	37	6	36273042
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	TCERG1 SF1 SF3B2 CPSF7	1.26e-05	134	37	4	25452129
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SMARCC2 ZNF207 RBM25 SF3B4 TCERG1 INF2 SF3A2 SF3B2 CPSF7	1.61e-05	1451	37	9	30550785
Pubmed	Recommendations for the investigation of animal models of Prader-Willi syndrome.	MAGEL2 SNRPN	1.65e-05	6	37	2	23609791
Pubmed	Sex reversal following deletion of a single distal enhancer of Sox9.	NR5A1 SF1	1.65e-05	6	37	2	29903884
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DIAPH1 FMN2 SMARCC2 RBM25 TAF3 BCL11B TAF1 ARHGAP33	1.85e-05	1116	37	8	31753913
Pubmed	Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos.	MAGEL2 SNRPN	2.30e-05	7	37	2	25300248
Pubmed	Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.	SF3B4 SF3B2	2.30e-05	7	37	2	28541300
Pubmed	Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-kappa B.	NR5A1 SF1	2.30e-05	7	37	2	12917325
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RBM25 TAF3 TAF1 TCERG1 ZNF598 PUF60	2.31e-05	549	37	6	38280479
Pubmed	Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.	TAF3 BCL11B TAF1	2.36e-05	52	37	3	35361962
Interaction	WBP4 interactions	DIAPH1 RBM42 ZNF207 SF3B4 TCERG1 FMN1 SNRPN SF3A2 SF1 SF3B2 CPSF7	5.25e-17	109	37	11	int:WBP4
Interaction	SNRPA interactions	RBM42 ZNF207 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7 ENOX2	6.14e-14	482	37	14	int:SNRPA
Interaction	PRPF40A interactions	DIAPH1 SMARCC2 RBM25 SF3B4 TCERG1 ZNF598 SNRPC PUF60 FMN1 SF3A2 SF1 SF3B2 CPSF7	5.64e-13	446	37	13	int:PRPF40A
Interaction	SNRPA1 interactions	SMARCC2 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	4.02e-12	300	37	11	int:SNRPA1
Interaction	SF3B4 interactions	RBM25 SF3B4 MAGEL2 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	1.65e-11	342	37	11	int:SF3B4
Interaction	SNRPB2 interactions	ZNF207 SMN1 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	2.28e-11	255	37	10	int:SNRPB2
Interaction	SNRPF interactions	RBM42 ZNF207 SMN1 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF3B2 CPSF7	5.88e-11	385	37	11	int:SNRPF
Interaction	TCERG1 interactions	DIAPH1 SMN1 SF3B4 TCERG1 SNRPC FMN1 SF3A2 SF1 SF3B2	1.04e-10	207	37	9	int:TCERG1
Interaction	SMC5 interactions	SMARCC2 ZNF207 SMN1 RBM25 TAF3 SF3B4 TAF1 TCERG1 SNRPC PUF60 SNRPN SF1 SF3B2 CPSF7	1.05e-09	1000	37	14	int:SMC5
Interaction	SF3A2 interactions	ZNF207 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	1.20e-09	273	37	9	int:SF3A2
Interaction	SNRPB interactions	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF3B2 CPSF7	1.33e-09	517	37	11	int:SNRPB
Interaction	HDLBP interactions	RBM42 TYRO3 SMARCC2 SMN1 RBM25 TAF3 SF3B4 TCERG1 ZNF598 PUF60 SF1 SF3B2 CPSF7	1.82e-09	855	37	13	int:HDLBP
Interaction	ACTC1 interactions	DIAPH1 FMN2 SMARCC2 RBM25 SF3B4 TCERG1 INF2 PUF60 SF3A2 SF1 SF3B2 CPSF7	2.13e-09	694	37	12	int:ACTC1
Interaction	MECP2 interactions	RBM42 FGD1 SMARCC2 ZNF207 RBM25 TAF3 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2 ARHGAP33 CPSF7	2.72e-09	1287	37	15	int:MECP2
Interaction	CWC15 interactions	FGD1 RBM25 SF3B4 SNRPC SF3A2 SF1 SF3B2	4.28e-09	134	37	7	int:CWC15
Interaction	SNRPC interactions	ZNF207 SMN1 RBM25 SF3B4 TCERG1 SNRPC SNRPN SF3A2 SF3B2 CPSF7	4.57e-09	440	37	10	int:SNRPC
Interaction	CD2BP2 interactions	RBM42 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2 CPSF7	7.92e-09	232	37	8	int:CD2BP2
Interaction	SF3A1 interactions	SMARCC2 RBM25 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	8.75e-09	471	37	10	int:SF3A1
Interaction	DOT1L interactions	SMARCC2 SMN1 NR5A1 RBM25 SF3B4 TCERG1 PUF60 SNRPN SF3A2 SF1 SF3B2 CPSF7	1.15e-08	807	37	12	int:DOT1L
Interaction	DMRTB1 interactions	RBM42 SF3B4 SNRPC SNRPN SF1 CPSF7	1.81e-08	94	37	6	int:DMRTB1
Interaction	CPSF6 interactions	RBM42 SMARCC2 SMN1 RBM25 TCERG1 SNRPC PUF60 SF3A2 SF3B2 CPSF7	2.49e-08	526	37	10	int:CPSF6
Interaction	CRNKL1 interactions	SF3B4 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	2.95e-08	177	37	7	int:CRNKL1
Interaction	SNRPG interactions	RBM42 SMN1 SF3B4 SNRPC SNRPN SF3A2 SF3B2	6.37e-08	198	37	7	int:SNRPG
Interaction	SMNDC1 interactions	RBM42 SF3B4 SNRPC PUF60 SF3A2 SF3B2	6.42e-08	116	37	6	int:SMNDC1
Interaction	SNRPE interactions	RBM42 SMN1 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2	6.62e-08	305	37	8	int:SNRPE
Interaction	DDX42 interactions	RBM25 SF3B4 TCERG1 SNRPC SF3A2 SF3B2 CPSF7	8.93e-08	208	37	7	int:DDX42
Interaction	BAG4 interactions	RBM42 SF3B4 SNRPC SNRPN SF1 CBFA2T2 CPSF7	1.48e-07	224	37	7	int:BAG4
Interaction	DDX23 interactions	RBM42 RBM25 TAF3 TAF1 TCERG1 SNRPC PUF60 SNRPN SF3A2	1.57e-07	480	37	9	int:DDX23
Interaction	MEN1 interactions	SMARCC2 SMN1 NR5A1 RBM25 SF3B4 TAF1 TCERG1 SNRPN SF3A2 SF1 SF3B2 CBFA2T2	1.67e-07	1029	37	12	int:MEN1
Interaction	SNRPD1 interactions	RBM42 SMN1 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2	1.78e-07	347	37	8	int:SNRPD1
Interaction	SRRM1 interactions	RBM42 SMARCC2 RBM25 SF3B4 SNRPC PUF60 SF3A2 SF3B2	1.82e-07	348	37	8	int:SRRM1
Interaction	SF3B5 interactions	FGD1 SF3B4 PUF60 SNRPN SF3A2 SF3B2	2.23e-07	143	37	6	int:SF3B5
Interaction	PUF60 interactions	DIAPH1 ZNF207 RBM25 SF3B4 PUF60 SF3A2 SF1 SF3B2	2.84e-07	369	37	8	int:PUF60
Interaction	SF3B2 interactions	RBM42 SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF1 SF3B2	2.95e-07	517	37	9	int:SF3B2
Interaction	SNRPD3 interactions	RBM42 SMN1 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2	3.55e-07	380	37	8	int:SNRPD3
Interaction	BCAS2 interactions	RBM25 SF3B4 SNRPC SNRPN SF3A2 SF1 CPSF7	5.23e-07	270	37	7	int:BCAS2
Interaction	SNW1 interactions	DIAPH1 RBM42 SMN1 SF3B4 SNRPC PUF60 SF3A2 SF1 SF3B2 CPSF7	6.47e-07	747	37	10	int:SNW1
Interaction	SNRPD2 interactions	RBM42 SMN1 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2	6.79e-07	414	37	8	int:SNRPD2
Interaction	MIR155 interactions	SF3B4 PUF60 SF1 SF3B2 CPSF7	6.90e-07	92	37	5	int:MIR155
Interaction	LSM4 interactions	RBM42 SMN1 TCERG1 SNRPC SNRPN SF3A2	8.08e-07	178	37	6	int:LSM4
Interaction	TFIP11 interactions	SF3B4 SNRPC SNRPN SF3A2 SF1 SF3B2 CPSF7 ENOX2	8.57e-07	427	37	8	int:TFIP11
Interaction	SNRNP70 interactions	RBM42 SMARCC2 SMN1 RBM25 SF3B4 SNRPC PUF60 SNRPN SF3A2 SF3B2 CPSF7	9.43e-07	984	37	11	int:SNRNP70
Interaction	SNRPN interactions	RBM42 SF3B4 SNRPC SNRPN SF3A2 SF3B2	1.04e-06	186	37	6	int:SNRPN
Interaction	SF1 interactions	SF3B4 TCERG1 PUF60 SF3A2 SF1 SF3B2 CPSF7	1.16e-06	304	37	7	int:SF1
Interaction	APBB1 interactions	DIAPH1 SF3B4 SF3A2 SF1 SF3B2 CPSF7	1.38e-06	195	37	6	int:APBB1
Interaction	SART1 interactions	RBM42 SMARCC2 RBM25 SNRPC SNRPN SF3A2 CPSF7	1.53e-06	317	37	7	int:SART1
Interaction	SNRNP40 interactions	RBM42 SMARCC2 ZNF207 RBM25 TCERG1 SNRPC SNRPN SF3A2 CPSF7	1.68e-06	637	37	9	int:SNRNP40
Interaction	RBM25 interactions	SMARCC2 SMN1 RBM25 SF3B4 SNRPC PUF60 CPSF7	1.73e-06	323	37	7	int:RBM25
Interaction	PRP4K interactions	RBM42 SMARCC2 RBM25 TCERG1 SNRPC SF3B2 CPSF7	1.96e-06	329	37	7	int:PRP4K
Interaction	SF3A3 interactions	SF3B4 TCERG1 SNRPC PUF60 SNRPN SF3A2 SF3B2	2.44e-06	340	37	7	int:SF3A3
Interaction	WDR77 interactions	ZNF207 SMN1 SF3B4 ZNF598 SNRPC SNRPN SF1	3.62e-06	361	37	7	int:WDR77
Interaction	EWSR1 interactions	SMARCC2 ZNF207 SMN1 SF3B4 TAF1 SNRPC PUF60 SF1 SF3B2 CPSF7	3.69e-06	906	37	10	int:EWSR1
Interaction	HNRNPM interactions	ZNF207 RBM25 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2	4.73e-06	723	37	9	int:HNRNPM
Interaction	RBM10 interactions	SF3B4 SNRPC SF3A2 SF1 SF3B2 CPSF7	6.19e-06	253	37	6	int:RBM10
Interaction	CIT interactions	RBM42 SMARCC2 RBM25 SF3B4 TCERG1 SNRPC INF2 PUF60 SF3A2 SF1 SF3B2 CPSF7	6.27e-06	1450	37	12	int:CIT
Interaction	FUS interactions	SMARCC2 SMN1 RBM25 SF3B4 TCERG1 SNRPC SF3A2 SF1 SF3B2	6.86e-06	757	37	9	int:FUS
Interaction	SRSF1 interactions	RBM25 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF3B2 CPSF7	7.30e-06	570	37	8	int:SRSF1
Interaction	SF3B1 interactions	RBM25 SF3B4 TCERG1 PUF60 SNRPN SF3A2 SF1 SF3B2	7.39e-06	571	37	8	int:SF3B1
Interaction	FMN1 interactions	FMN2 TCERG1 FMN1	9.84e-06	23	37	3	int:FMN1
Interaction	MIR16-1 interactions	SF3B4 PUF60 SF3B2 CPSF7	1.12e-05	76	37	4	int:MIR16-1
Interaction	TXNL4A interactions	RBM42 SNRPC SNRPN CPSF7	1.18e-05	77	37	4	int:TXNL4A
Interaction	RBFOX2 interactions	RBM42 SMN1 SF3B4 SNRPC SF1 CPSF7	1.20e-05	284	37	6	int:RBFOX2
Interaction	LSM5 interactions	RBM42 SNRPC SNRPN CPSF7	1.24e-05	78	37	4	int:LSM5
Interaction	RBM39 interactions	RBM42 SMN1 RBM25 SF3B4 TCERG1 SNRPC PUF60 SF3A2 SF1 SF3B2	1.27e-05	1042	37	10	int:RBM39
Interaction	PRPF3 interactions	RBM42 RBM25 SNRPC SNRPN SF3A2 SF3B2	1.37e-05	291	37	6	int:PRPF3
Interaction	PHF5A interactions	RBM25 SF3B4 PUF60 SF3A2 SF3B2	1.45e-05	171	37	5	int:PHF5A
Interaction	MIR10B interactions	SF3B4 PUF60 SF3B2 CPSF7	1.52e-05	82	37	4	int:MIR10B
Interaction	CTTN interactions	FGD1 RBM25 SF3B4 MAGEL2 SF1 SF3B2 CPSF7	1.52e-05	450	37	7	int:CTTN
Interaction	SRSF4 interactions	ENOX1 SNRPC SF3A2 SF3B2 CPSF7 ENOX2	1.63e-05	300	37	6	int:SRSF4
Interaction	MIR18B interactions	SF3B4 PUF60 SF3B2 CPSF7	1.75e-05	85	37	4	int:MIR18B
Interaction	SNRNP200 interactions	RBM42 SF3B4 SNRPC SNRPN SF3A2 SF1 SF3B2	1.76e-05	460	37	7	int:SNRNP200
Interaction	TAF2 interactions	RBM25 TAF3 TAF1 PUF60 CPSF7	1.76e-05	178	37	5	int:TAF2
Interaction	SUZ12 interactions	SMARCC2 ZNF207 TAF3 SF3B4 SNRPN SF1 SF3B2 CPSF7	1.77e-05	644	37	8	int:SUZ12
Interaction	SAP18 interactions	RBM42 SMARCC2 RBM25 TAF1 SNRPC SF3A2	1.79e-05	305	37	6	int:SAP18
Interaction	RNU11 interactions	SMN1 SF3B4 SF3B2	1.81e-05	28	37	3	int:RNU11
Interaction	CDC5L interactions	DIAPH1 RBM42 SMARCC2 SMN1 SF3B4 SNRPC SF3A2 SF3B2 CPSF7	1.82e-05	855	37	9	int:CDC5L
Interaction	FUBP1 interactions	SMARCC2 SMN1 RBM25 SNRPC PUF60 SF3A2	1.93e-05	309	37	6	int:FUBP1
Interaction	MIR141 interactions	SF3B4 PUF60 SF3B2 CPSF7	2.01e-05	88	37	4	int:MIR141
Interaction	PRMT5 interactions	SMARCC2 SMN1 SF3B4 TCERG1 ZNF598 SNRPC SNRPN	2.04e-05	471	37	7	int:PRMT5
Interaction	MIR29C interactions	SF3B4 PUF60 SF3B2 CPSF7	2.10e-05	89	37	4	int:MIR29C
Interaction	MIR1-1 interactions	SF3B4 PUF60 SF3B2 CPSF7	2.19e-05	90	37	4	int:MIR1-1
Interaction	ZC3H18 interactions	RBM42 ZNF207 RBM25 SF3B4 TCERG1 SNRPC SF3A2 SF1 SF3B2	2.22e-05	877	37	9	int:ZC3H18
Interaction	EXOSC8 interactions	ZNF598 SNRPC SNRPN SF1 CPSF7	2.23e-05	187	37	5	int:EXOSC8
Interaction	LSM2 interactions	RBM42 SMN1 SNRPC SNRPN SF3B2	2.47e-05	191	37	5	int:LSM2
Interaction	RUNX1 interactions	SMARCC2 TCERG1 SNRPC SF1 SF3B2 CBFA2T2	2.52e-05	324	37	6	int:RUNX1
Interaction	MIR19B2 interactions	SF3B4 PUF60 SF1 SF3B2	2.61e-05	94	37	4	int:MIR19B2
Interaction	LSM6 interactions	RBM42 SMN1 SNRPC SNRPN	2.61e-05	94	37	4	int:LSM6
Interaction	SF3B6 interactions	SF3B4 SNRPC PUF60 SF3A2 SF3B2	2.66e-05	194	37	5	int:SF3B6
Interaction	NSRP1 interactions	RBM25 SF3B4 SNRPC SF3B2 CPSF7	2.87e-05	197	37	5	int:NSRP1
Interaction	CTNNBL1 interactions	SF3B4 SNRPC SF3A2 SF1 SF3B2	2.87e-05	197	37	5	int:CTNNBL1
Interaction	MIR106B interactions	SF3B4 PUF60 SF1 SF3B2	3.07e-05	98	37	4	int:MIR106B
Interaction	PRPF6 interactions	RBM42 SF3B4 SNRPC SNRPN SF3A2 CPSF7	3.09e-05	336	37	6	int:PRPF6
Interaction	MIR128-2 interactions	SF3B4 PUF60 SF3B2 CPSF7	3.19e-05	99	37	4	int:MIR128-2
Interaction	RBPMS interactions	RBM42 SMARCC2 SNRPC SNRPN SF1 CPSF7	3.30e-05	340	37	6	int:RBPMS
Interaction	SRSF11 interactions	ZNF207 RBM25 TCERG1 PUF60 SF3B2	3.31e-05	203	37	5	int:SRSF11
Interaction	MIR19A interactions	SF3B4 PUF60 SF3B2 CPSF7	3.32e-05	100	37	4	int:MIR19A
Interaction	MIR25 interactions	SF3B4 PUF60 SF3B2 CPSF7	3.46e-05	101	37	4	int:MIR25
Interaction	PSPC1 interactions	SMN1 RBM25 SF3B4 TCERG1 ZNF598 SF3B2 CPSF7	3.62e-05	515	37	7	int:PSPC1
Interaction	CEBPB interactions	RBM42 SMARCC2 ZNF207 SMN1 RBM25 SF3B4 TCERG1 SNRPC SF3A2 SF1 SF3B2	3.67e-05	1443	37	11	int:CEBPB
Interaction	MIR7-1 interactions	SF3B4 PUF60 SF3B2 CPSF7	3.73e-05	103	37	4	int:MIR7-1
GeneFamily	RNA binding motif containing	RBM42 RBM25 SF3B4 ENOX1 PUF60 CPSF7 ENOX2	1.55e-08	213	26	7	725
Coexpression	TABULA_MURIS_SENIS_LARGE_INTESTINE_SECRETORY_CELL_AGEING	RBM42 RBM25 SF3B4 TCERG1 SNRPC PUF60 SF1 SF3B2	6.85e-06	734	37	8	MM3740
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000	ZNF207 SMN1 RBM25 TCERG1 SNRPC SNRPN SF3A2 SF1 ARHGAP33	1.07e-05	843	37	9	gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_1000	ZNF207 SMN1 TCERG1 SNRPC SNRPN SF3A2 SF1	2.09e-05	498	37	7	gudmap_developingGonad_e11.5_testes_k5_1000
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000	TYRO3 ZNF207 SMN1 NR5A1 RBM25 TCERG1 SNRPC SNRPN	6.76e-05	819	37	8	gudmap_developingGonad_e12.5_testes_1000
CoexpressionAtlas	DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000	ZNF207 SMN1 RBM25 TCERG1 SNRPC SNRPN SF1 SF3B2	8.34e-05	844	37	8	gudmap_developingGonad_e11.5_testes and mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_200	ZNF207 SMN1 NR5A1 SNRPN	1.90e-04	165	37	4	gudmap_developingGonad_e12.5_testes_200
ToppCell	facs-MAT-Fat-18m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM42 SF3B4 SNRPC SF3A2	1.75e-05	188	37	4	7f0cda7aab442aa9511d4c35569ec2389e014a71
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 ENOX1 FMN1 RGL3	1.79e-05	189	37	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 ENOX1 FMN1 RGL3	1.82e-05	190	37	4	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	facs-Tongue-nan-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMN1 SF3B4 SNRPC SF3A2	1.94e-05	193	37	4	45361266b5c6e9b229ef80ef692f01b48e5b38ed
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF207 RBM25 BCL11B SF1	2.10e-05	197	37	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MAGEL2 ENOX1 SOBP	2.50e-04	148	37	3	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MAGEL2 ENOX1 SOBP	2.50e-04	148	37	3	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	2.86e-04	155	37	3	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	2.86e-04	155	37	3	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	2.86e-04	155	37	3	90e629681a72baacc7981b82883866a487638dbc
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMN1 BCL11B SNRPN	2.91e-04	156	37	3	8790b4b400695571fcf1ccb24c658b5e90854ff7
ToppCell	Striatum-Neuronal-Inhibitory\|Striatum / BrainAtlas - Mouse McCarroll V32	ATG9B MAGEL2 FMN1	2.97e-04	157	37	3	c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ZNF207 BCL11B SF1	3.25e-04	162	37	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B SNRPC SF3A2	3.31e-04	163	37	3	a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	SMN1 ATG9B ZNF598	3.37e-04	164	37	3	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	SMN1 ATG9B ZNF598	3.37e-04	164	37	3	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG9B BCL11B SNRPN	3.49e-04	166	37	3	9e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX2 BCL11B ARHGAP33	3.68e-04	169	37	3	700a3a36c379872585204caa6a6cc269b036ae22
ToppCell	3'_v3-lymph-node_spleen\|World / Manually curated celltypes from each tissue	BCL11B SNRPN SF1	3.81e-04	171	37	3	7aae88da5b37c20f10118325a048f08906be994c
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TYRO3 ATG9B BCL11B	3.88e-04	172	37	3	ca0cc0e92b6cdce5016f18fcb2ec1508cb222502
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	3.88e-04	172	37	3	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	3.88e-04	172	37	3	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TYRO3 ATG9B BCL11B	3.88e-04	172	37	3	425970e9ce8943f7e2ba6ca958e7a3a29baa798c
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYRO3 FMN2 ATG9B	4.01e-04	174	37	3	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	4.01e-04	174	37	3	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMN1 BCL11B SNRPN	4.15e-04	176	37	3	dca70f309af24421f8dc708cbd88512814b8e79e
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNRPC SF3A2 SF3B2	4.29e-04	178	37	3	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	4.29e-04	178	37	3	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	TYRO3 FMN2 INF2	4.65e-04	183	37	3	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	4.65e-04	183	37	3	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ENOX1 FMN1 RGL3	4.72e-04	184	37	3	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	facs-Bladder-nan-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SF3B4 SNRPC SF3A2	4.79e-04	185	37	3	3e00879466e626aa8604efecfc4678d64f54dbfc
ToppCell	facs-Bladder-nan-18m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SF3B4 SNRPC SF3A2	4.79e-04	185	37	3	3dc5812c961ff209f197ff4cbfb90009c0537550
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TYRO3 FMN2 INF2	4.79e-04	185	37	3	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIAPH1 RBM25 TAF3	4.95e-04	187	37	3	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 FMN1 RGL3	5.02e-04	188	37	3	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 FMN1 RGL3	5.02e-04	188	37	3	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.02e-04	188	37	3	fe08277d5aa693a2e12786738d12ec6390e8d13d
ToppCell	facs-Tongue-nan-18m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMN1 SNRPC SF3A2	5.02e-04	188	37	3	a2fda11bba33ddefa48f93dd635e254d1a081218
ToppCell	mild_COVID-19-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	BCL11B SNRPN SF1	5.02e-04	188	37	3	ddfb1c64305825fb0bc23819aa001bfc2ac4c2b2
ToppCell	facs-Tongue-nan-18m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMN1 SNRPC SF3A2	5.02e-04	188	37	3	1b3f71de4631403938a9dc85a02af2feea0b919f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RBM25 BCL11B SF1	5.10e-04	189	37	3	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.10e-04	189	37	3	8130102c41b2978a8b83f765ce383f836a464795
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 FMN1 RGL3	5.10e-04	189	37	3	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM50 FMN1 RGL3	5.10e-04	189	37	3	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.26e-04	191	37	3	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH1 SNRPN RGL3	5.34e-04	192	37	3	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B SNRPN SF1	5.34e-04	192	37	3	348d39da3016dc6dbfa65d108e5def35aa7f19dd
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.34e-04	192	37	3	78546a6e077076834fd717607610ab6df3b6e7ba
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RBM25 BCL11B SF1	5.34e-04	192	37	3	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	facs-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SF3B4 SNRPC SF3A2	5.34e-04	192	37	3	1f81b356520b5506051383d37fae204d59795336
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.34e-04	192	37	3	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.34e-04	192	37	3	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	facs-Brain_Non-Myeloid-Striatum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B INF2 ARHGAP33	5.42e-04	193	37	3	d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B FMN1 SNRPN	5.42e-04	193	37	3	c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF207 BCL11B SF1	5.51e-04	194	37	3	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF207 BCL11B SF1	5.51e-04	194	37	3	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BCL11B ENOX1 SNRPN	5.51e-04	194	37	3	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	facs-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SF3B4 SNRPC SF3A2	5.51e-04	194	37	3	842636fcc64eb8f04eb4e30b6eb70410050880e9
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF207 BCL11B SF1	5.51e-04	194	37	3	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATG9B NR5A1 BCL11B	5.59e-04	195	37	3	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	10x5'v1-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	SNRPC SF3A2 ARHGAP33	5.67e-04	196	37	3	31229affb48521e8be93b6061178fd8cea09ba99
ToppCell	COVID-19_Severe-CD4+_T_naive\|World / disease group, cell group and cell class	BCL11B SNRPN SF1	5.67e-04	196	37	3	b47c89eca6053c309fd328251c4fa33a76d16889
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B SNRPN SF1	5.76e-04	197	37	3	ef2d1f56acd0be43e69bba7f73f6909ba87f1cb3
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	ZNF207 RBM25 SF1	5.76e-04	197	37	3	e666f6580e9a20b5e550f02125706db17eec8510
ToppCell	moderate-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DIAPH1 BCL11B SF1	5.84e-04	198	37	3	0a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B SNRPN SF1	5.84e-04	198	37	3	8a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B SNRPN SF1	5.84e-04	198	37	3	33a3b279c9ff3b762e52d060dae062167ca2239b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B SNRPN SF1	5.93e-04	199	37	3	3003badee037d4d63a8018a74c0aea213d049e43
ToppCell	severe-CD8+_T_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BCL11B SNRPN SF1	5.93e-04	199	37	3	656e639228b3f2dca6955a487e4999e73a69bc51
ToppCell	Caecum-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	BCL11B FMN1 SF1	5.93e-04	199	37	3	13173cc4dcc8e856680372b0a4ad4f36afa892c1
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_T_naive\|Leuk-UTI / Disease, condition lineage and cell class	ATG9B BCL11B SNRPN	6.01e-04	200	37	3	a542c302ac266ed0ead355b5011f0aff39320ed7
ToppCell	severe-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BCL11B SNRPN SF1	6.01e-04	200	37	3	f74bdabadca8ad6dae1b6e6812c66325aac50db0
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma\|TCGA-Liver / Sample_Type by Project: Shred V9	SF3B4 SNRPC PUF60	6.01e-04	200	37	3	bc7aba2885ca1093fcd884807b497700dae4835e
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	DIAPH1 RBM25 SF1	6.01e-04	200	37	3	7dec470c379cd89f05a0f37c8628b21f136e52f0
Drug	Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A	RBM42 ZFHX2 SMARCC2 SF3A2 SF1 ARHGAP33	7.02e-07	196	37	6	1344_UP
Drug	oleoresins	DIAPH1 ZNF207 SF3B4 TCERG1	6.96e-06	76	37	4	ctd:C018620
Disease	Prader-Willi syndrome (implicated_via_orthology)	MAGEL2 SNRPN	8.19e-06	4	35	2	DOID:11983 (implicated_via_orthology)
Disease	Royer Syndrome	MAGEL2 SNRPN	8.95e-05	12	35	2	C0265222
Disease	Prader-Willi Syndrome	MAGEL2 SNRPN	1.06e-04	13	35	2	C0032897
Disease	Intellectual Disability	DIAPH1 SMARCC2 BCL11B TAF1 PUF60	1.74e-04	447	35	5	C3714756
Disease	Arthrogryposis	SMN1 MAGEL2	2.83e-04	21	35	2	C0003886
Disease	Global developmental delay	DIAPH1 SMARCC2 TAF1	5.27e-04	133	35	3	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
PVPTGPPMAPVPPGP	ESX1	311	Q8N693
VPPGPPMARVPPGPP	ESX1	321	Q8N693
APLPPGPPMAPLPPG	ESX1	346	Q8N693
PLPGEAGMPPPPPPL	DIAPH1	706	O60610
MPPPGVVKLPPLPGS	DTX4	221	Q9Y2E6
PMGIPALPPGIPPPQ	RBM25	11	P49756
ALVGPPLPGPPGPPM	RBM42	191	Q9BTD8
ALPLMGLPPPPIPPP	CPSF7	231	Q8N684
APPMPPVSAGPPLPP	FMN1	891	Q68DA7
PAPPLGGPMGKPPTP	MAGEL2	91	Q9UJ55
KPPTPGVLMVHPPPP	MAGEL2	101	Q9UJ55
PGLGIVPPPIPPDMP	ENOX2	81	Q16206
PTMPPLPPINPGGPR	CBFA2T2	46	O43439
GFLLPPMPPPPPPGV	RGL3	111	Q3MIN7
PPLPGLGAMAPPAPP	INF2	461	Q27J81
LGAMAPPAPPLPPPL	INF2	466	Q27J81
GLGCPPPPPPLLPGM	INF2	496	Q27J81
PPPPPLLPGMGWGPP	INF2	501	Q27J81
LLPGMGWGPPPPPPP	INF2	506	Q27J81
PLGPDMESPLPPPPL	ARHGAP33	866	O14559
SPFLSTPPLPPMPPG	BCL11B	401	Q9C0K0
PMPPGGTPPPQPPAK	BCL11B	411	Q9C0K0
GPGSVPLLPMPLPPP	ATG9B	21	Q674R7
PGLGMVPPPPPPLPG	FMN2	871	Q9NZ56
EMLPPPPPPLPGAGI	FMN2	906	Q9NZ56
LPGAGIPPPPPLPGM	FMN2	1201	Q9NZ56
IPPPPPLPGMGIPPA	FMN2	1206	Q9NZ56
PLPGMGIPPAPAPPL	FMN2	1211	Q9NZ56
NPMIPGLGLVPPPPP	ENOX1	91	Q8TC92
PPAPAPAPGPMLVSP	TAF3	796	Q5VWG9
ETGPPMGVPPPPPPA	NR5A1	121	Q13285
PMPLLTPATPGGLPP	PUF60	306	Q9UHX1
PPPGMRPPMGPPIGL	SNRPN	191	P63162
PPAGAMIPPPPSLPG	SNRPC	71	P09234
MIPPPPSLPGPPRPG	SNRPC	76	P09234
IDCKLMPPPPPPPGP	TAF1	151	P21675
VPGPSPGPPEPVMLP	FGD1	231	P98174
PPPPMPGPRLGPGKP	SMN1	196	Q16637
NAPLGLPFGMPPPPP	SMARCC2	1076	Q8TAQ2
PGGLPLPPMPPTGPA	SF3A2	256	Q15428
LPPMPPTGPAPSGPP	SF3A2	261	Q15428
QLPGIPMPPPPLGLP	SF3B2	86	Q13435
LSPLLPGVPPPPAMG	nan	41	Q6ZSN1
LGLPPGLMGPGPPPP	ZFHX2	606	Q9C0A1
PPGGIPPPMGPPHLQ	TCERG1	81	O14776
PTMPGNPPGLLPPPP	SOBP	466	A7XYQ1
ALGGPCPPRMPPPPG	ZNF598	671	Q86UK7
PGAPGMPPGIPPLMP	ZNF207	151	O43670
LPMVLPPPSGPGPLS	TRIM50	466	Q86XT4
MVPLPPGVQPPLPPG	SF1	566	Q15637
GALPPGIPPAMPPPP	SF3B4	251	Q15427
SMGRPGLPPLPLPPP	TYRO3	6	Q06418