Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

MYO1C MYO10 SYNE1 MYO19 TRIOBP MPRIP MACF1 TRPV4 EPS8L3 FERMT2

1.29e-0522715710GO:0051015
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB PRKACG

1.63e-0571573GO:0004691
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB PRKACG

3.87e-0591573GO:0004690
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB PRKACG

5.50e-05101573GO:0004679
GeneOntologyMolecularFunctiontRNA-4-demethylwyosine synthase activity

TYW1B TYW1

6.14e-0521572GO:0102521
GeneOntologyMolecularFunctionplus-end directed microfilament motor activity

MYO10 MYO19

1.83e-0431572GO:0060002
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 LRP1

1.83e-0431572GO:0030226
GeneOntologyMolecularFunctionFMN binding

IYD TYW1B TYW1

2.48e-04161573GO:0010181
GeneOntologyMolecularFunctionWnt receptor activity

FZD9 FZD10 FZD2

2.99e-04171573GO:0042813
GeneOntologyMolecularFunctionapolipoprotein binding

ABCA1 LRP1 LRP4

4.93e-04201573GO:0034185
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA1 SPNS2 MFSD2B

4.93e-04201573GO:0046624
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

MYO10 DAPP1 FERMT2 ARAP2

5.92e-04491574GO:0005547
GeneOntologyMolecularFunctioncholesterol binding

ABCA1 CYP11A1 OSBPL1A OSBP2

1.12e-03581574GO:0015485
GeneOntologyMolecularFunctionprotein kinase A binding

AKAP12 PRKACA PRKACG CRYBG3

1.12e-03581574GO:0051018
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 ABCA4 MYO1C MYO10 TMEM94 MYO19 WRN UBA3 DICER1 ATP6V1H ACSF3 MACF1 DNAH8

1.15e-0361415713GO:0140657
GeneOntologyMolecularFunctionoxo-acid-lyase activity

TYW1B TYW1

1.26e-0371572GO:0016833
GeneOntologyBiologicalProcessmulticellular organismal-level water homeostasis

EXT1 AQP4 PRKACA PRKACB PRKACG TRPV4

2.48e-07351586GO:0050891
GeneOntologyBiologicalProcesshigh-density lipoprotein particle assembly

ABCA1 PRKACA PRKACB PRKACG

2.25e-06131584GO:0034380
GeneOntologyBiologicalProcessrenal water homeostasis

AQP4 PRKACA PRKACB PRKACG

4.35e-05261584GO:0003091
GeneOntologyBiologicalProcesspancreas regeneration

REG1A REG1B

5.83e-0521582GO:1990798
GeneOntologyBiologicalProcessmulticellular organismal-level chemical homeostasis

EXT1 AQP4 PRKACA PRKACB PRKACG TRPV4

6.73e-05901586GO:0140962
GeneOntologyBiologicalProcessplasma lipoprotein particle assembly

ABCA1 PRKACA PRKACB PRKACG

6.78e-05291584GO:0034377
GeneOntologyBiologicalProcessprotein-lipid complex assembly

ABCA1 PRKACA PRKACB PRKACG

1.14e-04331584GO:0065005
GeneOntologyBiologicalProcesscellular response to glucose stimulus

CASR SIN3A AQP4 LEPR IGF1R AGER PRKACA LRP1

1.38e-041961588GO:0071333
GeneOntologyBiologicalProcesscellular response to hexose stimulus

CASR SIN3A AQP4 LEPR IGF1R AGER PRKACA LRP1

1.53e-041991588GO:0071331
GeneOntologyBiologicalProcesscellular response to monosaccharide stimulus

CASR SIN3A AQP4 LEPR IGF1R AGER PRKACA LRP1

1.64e-042011588GO:0071326
GeneOntologyBiologicalProcessresponse to wounding

COL3A1 ARHGAP24 RTN4R MFSD2B EXT1 JMJD1C MYOF IGF1R AGER LRP1 MACF1 FERMT2 FER1L5 DCBLD2 NOTCH4

1.70e-0465915815GO:0009611
GeneOntologyBiologicalProcesspositive regulation of acinar cell proliferation

REG1A REG1B

1.74e-0431582GO:1904699
GeneOntologyBiologicalProcessneuron projection extension

RTN4R REG1A REG1B SPG11 SIN3A LRP1 MACF1 NTN1

2.00e-042071588GO:1990138
GeneOntologyCellularComponentcAMP-dependent protein kinase complex

PRKACA PRKACB PRKACG

4.80e-05101573GO:0005952
GeneOntologyCellularComponentleading edge membrane

MYO1C REG1A REG1B C2CD5 MACF1 TRPV4 EPS8L3 FERMT2

1.93e-042101578GO:0031256
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL3A1 P4HA2 CALR ERO1A BCHE COLGALT2 PRSS23 ARSD RNASET2 COL1A2

2.13e-0433215710GO:0005788
GeneOntologyCellularComponentcell surface

EPHB6 IL12RB2 ABCA1 CALR RTN4R CASR TMPRSS11F AQP4 CHRNA1 LEPR FZD9 AGER LRP1 LRP4 FZD10 TRPV4 LY75 FERMT2 DCBLD2 NOTCH4

2.56e-04111115720GO:0009986
GeneOntologyCellularComponentcell projection membrane

MYO1C MYO10 REG1A REG1B AQP4 C2CD5 FZD9 MACF1 TRPV4 EPS8L3 FERMT2

4.26e-0443115711GO:0031253
GeneOntologyCellularComponentfocal adhesion

ARHGAP24 CALR TRIOBP AKAP12 MPRIP LRP1 TRPV4 FLRT2 FERMT2 FZD2 HCK

4.26e-0443115711GO:0005925
GeneOntologyCellularComponentcell-substrate junction

ARHGAP24 CALR TRIOBP AKAP12 MPRIP LRP1 TRPV4 FLRT2 FERMT2 FZD2 HCK

5.36e-0444315711GO:0030055
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

VMP1 ABCA1 STIM2 RASGRF2 SAMD8 NOX5 CALR TMEM94 ERO1A SYNE1 MMP23B BFAR EXT1 PIGQ FZD9 BCAP29 ALG10 FLRT2 TMEM68 NOTCH4 SEC13

9.65e-04132715721GO:0042175
MousePhenoabnormal bone volume

WRN LEPR SBNO2 FZD9 ATP6V1H TNFSF11 AGER LRP4 IRAK3 COL1A2

2.92e-0617312310MP:0010874
DomainDysFC

MYOF FER1L5 TECPR1

2.32e-0641573SM00694
DomainDysFN

MYOF FER1L5 TECPR1

2.32e-0641573SM00693
DomainPeroxin/Ferlin

MYOF FER1L5 TECPR1

2.32e-0641573IPR006614
DomainPH

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP OSBPL1A DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2 TECPR1

4.18e-0627815712SM00233
DomainPH_DOMAIN

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP OSBPL1A DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2 TECPR1

4.34e-0627915712PS50003
DomainPH_domain

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP OSBPL1A DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2 TECPR1

4.50e-0628015712IPR001849
DomainPH

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2

2.45e-0522915710PF00169
DomainPH_dom-like

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP OSBPL1A DAPP1 OSBP2 EPS8L3 ARHGAP27 FERMT2 ARAP2 TECPR1

6.55e-0542615713IPR011993
DomaintRNA_wybutosine-synth

TYW1B TYW1

7.02e-0521572IPR013917
DomainWyosine_form

TYW1B TYW1

7.02e-0521572PF08608
DomainQuinoprotein_ADH-like_supfam

WDR88 EML6 GEMIN5 WDR87 ARHGAP27

8.16e-05531575IPR011047
DomainFrizzled

FZD9 FZD10 FZD2

9.15e-05111573IPR000539
DomainFrizzled

FZD9 FZD10 FZD2

9.15e-05111573PF01534
DomainFrizzled

FZD9 FZD10 FZD2

9.15e-05111573SM01330
DomainSAM

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

9.84e-05881576SM00454
Domain-

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP OSBPL1A DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2 TECPR1

1.19e-04391157122.30.29.30
DomainSAM_DOMAIN

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

1.50e-04951576PS50105
DomainSAM

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

1.69e-04971576IPR001660
DomainFerA

MYOF FER1L5

2.09e-0431572SM01200
DomainFerlin_A-domain

MYOF FER1L5

2.09e-0431572IPR012560
DomainFerA

MYOF FER1L5

2.09e-0431572PF08165
Domain-

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

2.74e-0410615761.10.150.50
DomainFrizzled/SFRP

FZD9 FZD10 FZD2

3.01e-04161573IPR015526
DomainLep_receptor_Ig

IL12RB2 LEPR

4.17e-0441572PF06328
DomainIgC2-like_lig-bd

IL12RB2 LEPR

4.17e-0441572IPR010457
DomainTRPV1-4_channel

TRPV4 TRPV3

4.17e-0441572IPR008347
DomainSAM/pointed

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

4.65e-041171576IPR013761
DomainFRI

FZD9 FZD10 FZD2

5.98e-04201573SM00063
DomainKinase-like_dom

EPHB6 MAP3K14 SRPK1 IGF1R CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 MACF1 IRAK3 HCK

6.77e-0454215713IPR011009
DomainFerI

MYOF FER1L5

6.91e-0451572SM01202
DomainFerB

MYOF FER1L5

6.91e-0451572SM01201
DomainWSC

WSCD1 WSCD2

6.91e-0451572SM00321
DomainFerlin_B-domain

MYOF FER1L5

6.91e-0451572IPR012561
DomainFerlin_C

MYOF FER1L5

6.91e-0451572PF16165
DomainFerlin_C

MYOF FER1L5

6.91e-0451572IPR032362
DomainFerIin_dom

MYOF FER1L5

6.91e-0451572IPR012968
DomainFerI

MYOF FER1L5

6.91e-0451572PF08151
DomainFerB

MYOF FER1L5

6.91e-0451572PF08150
DomainWSC

WSCD1 WSCD2

6.91e-0451572PS51212
DomainWSC_carb-bd

WSCD1 WSCD2

6.91e-0451572IPR002889
DomainWSC

WSCD1 WSCD2

6.91e-0451572PF01822
Domain-

FZD9 FZD10 FZD2

6.93e-042115731.10.2000.10
DomainProt_kinase_dom

EPHB6 MAP3K14 SRPK1 IGF1R CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 IRAK3 HCK

8.94e-0448915712IPR000719
DomainPROTEIN_KINASE_DOM

EPHB6 MAP3K14 SRPK1 IGF1R CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 IRAK3 HCK

9.59e-0449315712PS50011
DomainFrizzled_dom

FZD9 FZD10 FZD2

1.04e-03241573IPR020067
DomainFZ

FZD9 FZD10 FZD2

1.04e-03241573PS50038
DomainFz

FZD9 FZD10 FZD2

1.04e-03241573PF01392
DomainHematopoietin_rcpt_Gp130_CS

IL12RB2 LEPR

1.43e-0371572IPR003529
DomainPROTEIN_KINASE_ATP

MAP3K14 SRPK1 IGF1R CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 IRAK3 HCK

1.76e-0345915711PS00107
DomainFlavodoxin/NO_synth

TYW1B TYW1

1.90e-0381572IPR008254
DomainFlavdoxin-like

TYW1B TYW1

1.90e-0381572IPR001094
DomainHEMATOPO_REC_L_F2

IL12RB2 LEPR

1.90e-0381572PS01353
DomainFLAVODOXIN_LIKE

TYW1B TYW1

1.90e-0381572PS50902
DomainFlavodoxin_1

TYW1B TYW1

1.90e-0381572PF00258
DomainrSAM

TYW1B TYW1

2.43e-0391572IPR007197
DomainPapD-like

CFAP65 TMEM131

2.43e-0391572IPR008962
DomainRadical_SAM

TYW1B TYW1

2.43e-0391572PF04055
DomainSAM_1

SAMD8 BFAR SAMD7 ARAP2

2.58e-03681574PF00536
Domain-

TYW1B TYW1

3.02e-031015723.40.50.360
DomainFlavoprotein-like_dom

TYW1B TYW1

3.02e-03101572IPR029039
DomainPROTEIN_KINASE_ST

MAP3K14 SRPK1 CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 IRAK3

3.59e-033621579PS00108
DomainNC1_FIB

COL3A1 COL1A2

3.67e-03111572PS51461
DomainFib_collagen_C

COL3A1 COL1A2

3.67e-03111572PD002078
DomainFib_collagen_C

COL3A1 COL1A2

3.67e-03111572IPR000885
DomainCOLFI

COL3A1 COL1A2

3.67e-03111572PF01410
DomainCOLFI

COL3A1 COL1A2

3.67e-03111572SM00038
DomainMyosin_head_motor_dom

MYO1C MYO10 MYO19

3.96e-03381573IPR001609
DomainMYOSIN_MOTOR

MYO1C MYO10 MYO19

3.96e-03381573PS51456
DomainMyosin_head

MYO1C MYO10 MYO19

3.96e-03381573PF00063
DomainMYSc

MYO1C MYO10 MYO19

3.96e-03381573SM00242
DomainOxysterol-bd_CS

OSBPL1A OSBP2

4.38e-03121572IPR018494
DomainABC_A

ABCA1 ABCA4

4.38e-03121572IPR026082
DomainOxysterol_BP

OSBPL1A OSBP2

4.38e-03121572PF01237
DomainOxysterol-bd

OSBPL1A OSBP2

4.38e-03121572IPR000648
DomainOSBP

OSBPL1A OSBP2

4.38e-03121572PS01013
DomainIQ

MYO1C RASGRF2 MYO10 MYO19

4.84e-03811574SM00015
DomainPkinase

MAP3K14 SRPK1 CLK1 BUB1B PRKACA PRKACB PRKACG ULK4 IRAK3

5.00e-033811579PF00069
DomainLectin_C

REG1A REG1B KLRF2 LY75

5.51e-03841574PF00059
DomainCLECT

REG1A REG1B KLRF2 LY75

5.51e-03841574SM00034
DomainC-type_lectin_CS

REG1A REG1B LY75

5.62e-03431573IPR018378
DomainC_TYPE_LECTIN_2

REG1A REG1B KLRF2 LY75

5.74e-03851574PS50041
DomainLdl_recept_b

LRP1 LRP4

5.98e-03141572PF00058
DomainLDLRB

LRP1 LRP4

5.98e-03141572PS51120
DomainC-type_lectin-like

REG1A REG1B KLRF2 LY75

5.98e-03861574IPR001304
DomainWD40

RAE1 WDR88 EML6 GEMIN5 WDR87 ELP2 SEC13

6.38e-032591577PF00400
DomainLY

LRP1 LRP4

6.86e-03151572SM00135
DomainLDLR_classB_rpt

LRP1 LRP4

6.86e-03151572IPR000033
DomainIQ_motif_EF-hand-BS

MYO1C RASGRF2 MYO10 MYO19

7.02e-03901574IPR000048
DomainWD40

RAE1 WDR88 EML6 GEMIN5 WDR87 ELP2 SEC13

7.63e-032681577SM00320
DomainIQ

MYO1C RASGRF2 MYO10 MYO19

7.86e-03931574PS50096
DomainWD40_repeat

RAE1 WDR88 EML6 GEMIN5 WDR87 ELP2 SEC13

8.25e-032721577IPR001680
PathwayREACTOME_HDL_ASSEMBLY

ABCA1 PRKACA PRKACB PRKACG

3.08e-0781174M27840
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD9 LRP4 FZD10 FZD2

4.23e-06141174M47834
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB PRKACG

5.51e-0651173M26988
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

ABCA1 PRKACA PRKACB PRKACG

1.59e-05191174M27841
PathwayKEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME

PRKACA PRKACB PRKACG

1.90e-0571173M47896
PathwayREACTOME_HDL_ASSEMBLY

ABCA1 PRKACA PRKACB

1.90e-0571173MM15560
PathwayREACTOME_ROBO_RECEPTORS_BIND_AKAP5

PRKACA PRKACB PRKACG

4.51e-0591173M27877
PathwayKEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

6.41e-05101173M47648
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

ERO1A ATP6V1H PRKACA PRKACB PRKACG

8.26e-05541175M17906
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PRKACA PRKACB PRKACG

1.16e-04121173M27950
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

PRKACA PRKACB PRKACG

1.16e-04121173M27363
PathwayWP_DOPAMINE_METABOLISM

PRKACA PRKACB PRKACG

1.50e-04131173M39622
PathwayREACTOME_METABOLISM_OF_LIPIDS

ABCA1 SAMD8 CYP11A1 SPNS2 CYP24A1 MFSD2B BCHE SIN3A ARSD MECR ST6GALNAC5 OSBPL1A PRKACA PRKACB PRKACG AGK ACSF3

1.64e-0475711717M27451
PathwayKEGG_MELANOGENESIS

FZD9 PRKACA PRKACB PRKACG FZD10 FZD2

1.92e-041011176M7761
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.36e-04151173M47794
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.36e-04151173M47504
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.88e-04161173M47551
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.88e-04161173M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.88e-04161173M47650
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD9 FZD10 FZD2

2.88e-04161173M47823
PathwayREACTOME_RAP1_SIGNALLING

PRKACA PRKACB PRKACG

2.88e-04161173M923
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

ABCA1 PRKACA PRKACB

3.48e-04171173MM15561
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

PRKACA PRKACB PRKACG

3.48e-04171173M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.48e-04171173M47544
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

AQP4 PRKACA PRKACB PRKACG

4.33e-04431174M933
PathwayWP_VASOPRESSINREGULATED_WATER_REABSORPTION

AQP4 PRKACA PRKACB PRKACG

4.74e-04441174M42554
PathwayKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

AQP4 PRKACA PRKACB PRKACG

4.74e-04441174M9011
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD9 FZD10 FZD2

4.90e-04191173M47833
PathwayREACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS

COL3A1 CALR COL1A2

4.90e-04191173M27221
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

PRKACA PRKACB PRKACG

5.73e-04201173M759
PathwayWP_MRNA_PROCESSING

SRPK1 PRPF6 DICER1 CLK1 CPSF1 SF3A2

6.30e-041261176M39406
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PRKACA PRKACB PRKACG

6.64e-04211173M27485
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD9 IGF1R PRKACG FZD10 FZD2

6.99e-04851175M48315
PathwayREACTOME_GLUCOSE_METABOLISM

RAE1 PRKACA PRKACB PRKACG SEC13

6.99e-04851175M1870
PathwayKEGG_APOPTOSIS

MAP3K14 PRKACA PRKACB PRKACG IRAK3

7.77e-04871175M8492
PathwayBIOCARTA_IGF1R_PATHWAY

IGF1R PRKACB PRKACG

8.74e-04231173M19613
PathwayKEGG_TASTE_TRANSDUCTION

PRKACA PRKACB PRKACG TAS2R41

8.97e-04521174M5785
PathwayREACTOME_AQUAPORIN_MEDIATED_TRANSPORT

AQP4 PRKACA PRKACB PRKACG

8.97e-04521174M920
PathwayREACTOME_TRIGLYCERIDE_CATABOLISM

PRKACA PRKACB PRKACG

9.93e-04241173M10064
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

9.93e-04241173M47520
PathwayREACTOME_DARPP_32_EVENTS

PRKACA PRKACB PRKACG

9.93e-04241173M751
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB

1.00e-0361172MM14628
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGAP24 RASGRF2 ARHGAP27 DOCK6 ARAP2

1.10e-03941175MM15598
PathwayBIOCARTA_BAD_PATHWAY

IGF1R PRKACB PRKACG

1.12e-03251173M85
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.26e-03261173M47553
PathwayPID_IL3_PATHWAY

PRKACA PRKACB PRKACG

1.26e-03261173M182
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

SAMD8 SPNS2 MFSD2B

1.41e-03271173MM14646
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.41e-03271173M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.41e-03271173M47519
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.57e-03281173M47647
PathwayPID_WNT_SIGNALING_PATHWAY

FZD9 FZD10 FZD2

1.57e-03281173M77
PathwayBIOCARTA_NO1_PATHWAY

CHRNA1 PRKACB PRKACG

1.57e-03281173M4383
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD9 PRKACA PRKACB PRKACG FZD10 FZD2

1.61e-031511176M19428
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL3A1 P4HA2 COLGALT2 COL1A2

1.63e-03611174MM14637
PathwayWP_LIPID_METABOLISM_PATHWAY

PRKACA PRKACB PRKACG

1.74e-03291173M39762
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.74e-03291173M47627
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

PRKACA PRKACB PRKACG

1.74e-03291173M39676
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.74e-03291173M47515
PathwayWP_BREAST_CANCER_PATHWAY

FZD9 IGF1R TNFSF11 FZD10 FZD2 NOTCH4

1.78e-031541176M39739
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

PRKACA PRKACB PRKACG

1.92e-03301173M42578
PathwayREACTOME_SPHINGOLIPID_METABOLISM

SAMD8 SPNS2 MFSD2B ARSD ST6GALNAC5

1.96e-031071175M14857
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

AQP4 PRKACA PRKACB

2.11e-03311173MM15094
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.11e-03311173M47507
Pubmed

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

PRKACA PRKACB PRKACG

1.01e-073163319383776
Pubmed

Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein.

PRKACA PRKACB PRKACG

1.01e-073163312842892
Pubmed

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

1.01e-07316332342480
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STIM2 CALR ERO1A SYNE1 TRIOBP SRPK1 SPG11 PRPF6 HEATR1 DICER1 AKAP12 C2CD5 MPRIP SLC38A2 BUB1B PRKACA PRKACB MACF1 TMEM131 ELP2 TYW1 SAMM50 CRYBG3 FERMT2

1.29e-0714871632433957083
Pubmed

Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.

PRKACA PRKACB TRPV4

4.03e-074163323709216
Pubmed

Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype.

PRKACA PRKACB PRKACG

4.03e-074163318385332
Pubmed

HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling.

PRKACA PRKACB PRKACG

1.00e-065163312972513
Pubmed

Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts.

PRKACA PRKACB PRKACG

1.00e-06516339540970
Pubmed

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction.

PRKACA PRKACB PRKACG

1.00e-065163321745501
Pubmed

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PRKACA PRKACB PRKACG

1.00e-065163319483721
Pubmed

PKA-mediated stabilization of FoxH1 negatively regulates ERalpha activity.

PRKACA PRKACB PRKACG

1.00e-065163319711044
Pubmed

Architectural DNA-binding properties of the spermatidal transition proteins 1 and 2.

PRKACA PRKACB PRKACG

2.00e-06616339837753
Pubmed

Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

PRKACA PRKACB PRKACG

2.00e-066163319197368
Pubmed

Dynamic binding of PKA regulatory subunit RI alpha.

PRKACA PRKACB PRKACG

3.49e-067163316407073
Pubmed

Phosphorylation of HIV Nef by cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

3.49e-067163315629779
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYO1C WRN GEMIN5 SRPK1 DICER1 MPRIP MYOF DOCK6

5.42e-06202163833005030
Pubmed

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

PRKACA PRKACB PRKACG

5.56e-068163312628924
Pubmed

CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway.

PRKACA PRKACB PRKACG

5.56e-068163319100722
Pubmed

Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha.

CHRNA1 PRKACA PRKACB

5.56e-06816338794865
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

ABCA1 JMJD1C TYW1B LRP1 LRP4 MACF1 DOCK6

6.13e-06146163720686565
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

STIM2 TMEM94 SRPK1 SIN3A DICER1 C2CD5 MPRIP PIGQ MYOF GTF2H3 IGF1R CLK1 BUB1B PRKACB IRAK3 HCK

6.54e-069101631636736316
Pubmed

Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes.

PRKACA PRKACB PRKACG

8.32e-06916337688126
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD9 FZD10 FZD2

8.32e-06916339707618
Pubmed

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition.

PRKACA PRKACB PRKACG

1.18e-0510163320433920
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD9 FZD10 FZD2

1.18e-0510163315245425
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL3A1 VMP1 P4HA2 STIM2 CALR ERO1A EXT1 PRSS23 SLC38A2 MYOF IGF1R BCAP29 LRP1 CPSF1 LRP4 TMEM131 TYW1 DCBLD2

1.49e-0512011631835696571
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD9 FZD10 FZD2

1.62e-0511163317576136
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD9 FZD10 FZD2

1.62e-0511163317582687
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD9 FZD10 FZD2

1.62e-0511163324860427
Pubmed

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

PRKACA PRKACB PRKACG

2.16e-0512163310830164
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

2.18e-05216323023318
Pubmed

Myo1c regulates glucose uptake in mouse skeletal muscle.

MYO1C LEPR

2.18e-052163221127070
Pubmed

Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptor-related protein: implication for receptor-mediated endocytosis.

PRKACA LRP1

2.18e-052163211158305
Pubmed

Cleavage of the Arg-Ile bond in the native polypeptide chain of human pancreatic stone protein.

REG1A REG1B

2.18e-05216323108036
Pubmed

The human reg gene encodes pancreatic stone protein.

REG1A REG1B

2.18e-05216322764894
Pubmed

Pancreatic acinar-specific overexpression of Reg2 gene offered no protection against either experimental diabetes or pancreatitis in mice.

REG1A REG1B

2.18e-052163220489047
Pubmed

Pancreatic regenerating gene overexpression in the nonobese diabetic mouse during active diabetogenesis.

REG1A REG1B

2.18e-05216328522062
Pubmed

Direct inhibitory and indirect stimulatory effects of RAGE ligand S100 on sRANKL-induced osteoclastogenesis.

TNFSF11 AGER

2.18e-052163219415676
Pubmed

An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.

AQP4 TRPV4

2.18e-052163221262839
Pubmed

Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)- and calmodulin-mediated mechanism.

AQP4 TRPV4

2.18e-052163228925524
Pubmed

Evaluation of AQP4/TRPV4 Channel Co-expression, Microvessel Density, and its Association with Peritumoral Brain Edema in Intracranial Meningiomas.

AQP4 TRPV4

2.18e-052163233538957
Pubmed

1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.

AGER LRP1

2.18e-052163226820600
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

2.18e-052163236152045
Pubmed

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections.

LRP1 ULK4

2.18e-052163227569546
Pubmed

Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice.

REG1A REG1B

2.18e-052163223986224
Pubmed

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins.

AQP4 TRPV4

2.18e-052163226413835
Pubmed

Type III collagen is a major component of interodontoblastic fibers of the developing mouse molar root.

COL3A1 COL1A2

2.18e-05216327825727
Pubmed

RegII is a beta-cell protein and autoantigen in diabetes of NOD mice.

REG1A REG1B

2.18e-052163217192462
Pubmed

Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation.

REG1A REG1B

2.18e-05216328654365
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

2.18e-05216322833513
Pubmed

TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes.

TRPV4 TRPV3

2.18e-052163215004014
Pubmed

A novel gene activated in regenerating islets.

REG1A REG1B

2.18e-05216322963000
Pubmed

Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.

IGF1R COL1A2

2.18e-052163224782617
Pubmed

Partial amino acid sequence of human pancreatic stone protein, a novel pancreatic secretory protein.

REG1A REG1B

2.18e-05216323541906
Pubmed

Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

TYW1B TYW1

2.18e-052163216162496
Pubmed

Isolation, structural determination and expression of a novel reg gene, human regI beta.

REG1A REG1B

2.18e-05216328110835
Pubmed

In vivo evidence for the role of RegI in gastric regeneration: transgenic overexpression of RegI accelerates the healing of experimental gastric ulcers.

REG1A REG1B

2.18e-052163220157293
Pubmed

mReg2 inhibits nuclear entry of apoptosis-inducing factor in mouse insulinoma cells.

REG1A REG1B

2.18e-052163225370781
Pubmed

N-terminal sequence extension in the glycosylated forms of human pancreatic stone protein. The 5-oxoproline N-terminal chain is O-glycosylated on the 5th amino acid residue.

REG1A REG1B

2.18e-05216322493268
Pubmed

Isolation and characterization of human reg protein produced in Saccharomyces cerevisiae.

REG1A REG1B

2.18e-05216322226837
Pubmed

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct.

PRKACA PRKACB

2.18e-052163231678302
Pubmed

Systems-level identification of PKA-dependent signaling in epithelial cells.

PRKACA PRKACB

2.18e-052163228973931
Pubmed

Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet-Induced Obesity.

REG1A REG1B

2.18e-052163228009527
Pubmed

Warm temperatures activate TRPV4 in mouse 308 keratinocytes.

TRPV4 TRPV3

2.18e-052163212783886
Pubmed

Gravin dynamics regulates the subcellular distribution of PKA.

AKAP12 PRKACA

2.18e-052163219210988
Pubmed

Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene.

REG1A REG1B

2.18e-05216322332435
Pubmed

The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells.

REG1A REG1B

2.18e-052163210526060
Pubmed

Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts.

COL3A1 COL1A2

2.18e-05216322981217
Pubmed

Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms.

PRKACA PRKACB

2.18e-052163237871652
Pubmed

Isolation, characterization, and distribution of an unusual pancreatic human secretory protein.

REG1A REG1B

2.18e-05216323908481
Pubmed

Secretory pancreatic stone protein messenger RNA. Nucleotide sequence and expression in chronic calcifying pancreatitis.

REG1A REG1B

2.18e-05216322525567
Pubmed

IGF-1R and Leptin Expression Profile and the Effects of Metformin Treatment on Metabolic and Endocrine Parameters in PCOS Mice.

LEPR IGF1R

2.18e-052163229430464
Pubmed

A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor.

SRPK1 CLK1

2.18e-052163232359191
Pubmed

Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma.

REG1A REG1B

2.18e-052163227539087
Pubmed

Helicobacter and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements.

REG1A REG1B

2.18e-052163217463184
Pubmed

AQP4 regulates ferroptosis and oxidative stress of Muller cells in diabetic retinopathy by regulating TRPV4.

AQP4 TRPV4

2.18e-052163238735619
Pubmed

The expression of REG 1A and REG 1B is increased during acute amebic colitis.

REG1A REG1B

2.18e-052163221586335
Pubmed

The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.

TRPV4 TRPV3

2.18e-052163225351988
Pubmed

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.

TRPV4 TRPV3

2.18e-052163219164517
Pubmed

TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation.

TRPV4 TRPV3

2.18e-052163221586160
Pubmed

Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel.

CASR TRPV4

2.18e-052163228951460
Pubmed

The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury.

AQP4 TRPV4

2.18e-052163236568889
Pubmed

Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.

ABCA1 PRKACA

2.18e-052163212196520
Pubmed

Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response.

LEPR NTN1

2.18e-052163237037837
Pubmed

Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.

SRPK1 CLK1

2.18e-052163227397683
Pubmed

TRPV4-AQP4 interactions 'turbocharge' astroglial sensitivity to small osmotic gradients.

AQP4 TRPV4

2.18e-052163226760501
Pubmed

Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.

LEPR IGF1R

2.18e-052163219122171
Pubmed

Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

REG1A REG1B

2.18e-052163212475793
Pubmed

The rheumatoid arthritis shared epitope triggers innate immune signaling via cell surface calreticulin.

CALR LRP1

2.18e-052163217947714
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

2.18e-052163238841868
Pubmed

Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.

REG1A REG1B

2.18e-052163217898082
Pubmed

Nε-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesity-induced dysregulation of adipokine expression and insulin resistance.

LEPR AGER

2.18e-052163224723555
Pubmed

Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin.

REG1A REG1B

2.18e-052163225747353
Pubmed

Complete amino acid sequence of an immunoreactive form of human pancreatic stone protein isolated from pancreatic juice.

REG1A REG1B

2.18e-05216323665916
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

2.18e-052163212139926
Pubmed

Carboxypeptidase A1 and regenerating islet-derived 1α as new markers for pancreatic acinar cell carcinoma.

CPA1 REG1A

2.18e-052163232702400
Pubmed

No abnormalities of reg1 alpha and reg1 beta gene associated with diabetes mellitus.

REG1A REG1B

2.18e-052163211796176
Pubmed

Protein-X, Pancreatic Stone-, Pancreatic thread-, reg-protein, P19, lithostathine, and now what? Characterization, structural analysis and putative function(s) of the major non-enzymatic protein of pancreatic secretions.

REG1A REG1B

2.18e-052163212369899
Pubmed

TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.

AQP4 TRPV4

2.18e-052163226424896
Pubmed

Functional screening and rational design of compounds targeting GPR132 to treat diabetes.

LEPR GPR132

2.18e-052163237770763
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP24 RASGRF2 MYO10 TRIOBP MPRIP DAPP1 OSBP2 ARHGAP27 FERMT2 ARAP2

3.34e-0720610510682
GeneFamilySterile alpha motif domain containing

EPHB6 STIM2 SAMD8 BFAR SAMD7 ARAP2

1.22e-05881056760
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD9 FZD10 FZD2

3.04e-05111053286
GeneFamilyFerlin family

MYOF FER1L5

4.94e-0461052828
GeneFamilyWD repeat domain containing

RAE1 WDR88 EML6 GEMIN5 WDR87 ELP2 SEC13

8.43e-042621057362
GeneFamilyCyclins|F-boxes other

FBXO40 FBXO16 FBXO4

1.49e-03391053560
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

REG1A REG1B KLRF2

1.73e-034110531298
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL1A OSBP2

2.12e-03121052670
GeneFamilyLow density lipoprotein receptors

LRP1 LRP4

2.50e-03131052634
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA4

2.90e-03141052805
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MYO10 MAP3K14 WRN SPG11 EXT1 DICER1 C2CD5 MYOF ATP6V1H IGF1R BUB1B PRKACB MACF1 CDYL TMEM131 FLRT2 CRYBG3 FERMT2 ARAP2 COL1A2

4.03e-0785616320M4500
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN

SYNE1 SPG11 MYOF BRDT SYTL3 TMEM131 DOCK6 DNAH8 GPR132

4.57e-061991639M4571
CoexpressionGSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN

CALR MYO10 SENP3 MAP3K14 MFSD2B URB2 OSBPL1A DCBLD2 GPR132

4.76e-062001639M9344
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 MYO10 SYNE1 MMP23B BCHE PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

1.92e-101991621130d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 MYO10 SYNE1 MMP23B AKAP12 MYOF LRP1 MACF1 COL1A2

2.99e-0919716210fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 SYNE1 MMP23B BCHE PRSS23 AKAP12 LRP1 MACF1 COL1A2

3.46e-0920016210bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 P4HA2 AKAP12 LRP1 TRPV3 OSBP2 FLRT2 FZD2 COL1A2

2.25e-0818116293462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 P4HA2 AKAP12 LRP1 TRPV3 OSBP2 FLRT2 FZD2 COL1A2

2.25e-0818116296730e249cac55ae892cc567d9211615882f3dab4
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 P4HA2 MMP23B IYD AKAP12 NTN1 FLRT2 FZD2 COL1A2

3.75e-081921629c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B IYD PRSS23 AKAP12 NTN1 FLRT2 FZD2 COL1A2

3.75e-0819216290e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B IYD PRSS23 AKAP12 NTN1 FLRT2 FZD2 COL1A2

3.92e-081931629025836c5c5a711e477c326559e618e47cae42d11
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B TRIOBP PRSS23 LRP1 IRAK3 FLRT2 DCBLD2 COL1A2

4.47e-081961629ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCelldistal-mesenchymal-Mesothelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL3A1 EPHB6 CYP11A1 MMP23B CPA1 BCHE FLRT2 DCBLD2 COL1A2

4.88e-08198162952e3cb45472dd6db31ae533e9ea0c3b550f11496
ToppCelldistal-mesenchymal-Mesothelial-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL3A1 EPHB6 CYP11A1 MMP23B CPA1 BCHE FLRT2 DCBLD2 COL1A2

4.88e-081981629431bf719ee5cce4c9e8b6b405819b67e98fad3ca
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 MYO10 SYNE1 MMP23B MYOF LRP1 MACF1 COL1A2

5.09e-081991629a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.09e-081991629e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-0820016299b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B BCHE PRSS23 AKAP12 LRP1 MACF1 COL1A2

5.32e-08200162964ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-082001629b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-08200162950ca6550998e461ef26dd670351060bd940765a8
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 MYO10 MMP23B AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-082001629a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-0820016293bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-08200162944a68bacdb3d5bf563bd35952176995850933a81
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B BCHE PRSS23 AKAP12 LRP1 MACF1 COL1A2

5.32e-082001629a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

5.32e-082001629dc61016c61729f69649cfb21f6264e685ce83dea
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSCD1 EML6 BFAR SIN3A URB2 LEPR CRYBG3 TMEM68

1.15e-071571628a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MMP23B PRSS23 LRP1 LRP4 ULK4 DCBLD2 COL1A2

2.76e-071761628cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL3A1 P4HA2 ZNF775 AKAP12 NTN1 FLRT2 FZD2 COL1A2

2.76e-07176162808f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MMP23B PRSS23 LRP1 LRP4 ULK4 DCBLD2 COL1A2

2.76e-071761628c0a084f7a8645262d61971f094689e02bf15b113
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

COL3A1 MMP23B CPA1 BCHE AKAP12 WSCD2 FLRT2 COL1A2

3.57e-071821628354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 CYP11A1 MMP23B CPA1 BCHE FLRT2 DCBLD2 COL1A2

4.95e-071901628f39ce1678fc375eb2a3af781ddb772b0f12c5744
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 P4HA2 MMP23B AKAP12 LRP1 FLRT2 FZD2 COL1A2

5.15e-0719116289f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL3A1 MMP23B BCHE COLGALT2 PRSS23 AKAP12 FLRT2 COL1A2

5.35e-071921628e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B IYD AKAP12 NTN1 FLRT2 FZD2 COL1A2

5.35e-071921628f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 P4HA2 MMP23B AKAP12 LRP1 FLRT2 FZD2 COL1A2

5.57e-071931628051f61156b0e2e95292b2d8377faf3190b50f264
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MMP23B IYD AKAP12 NTN1 FLRT2 FZD2 COL1A2

5.57e-071931628858a186804b36d45957238d3d3eed2768b961641
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MMP23B IYD AKAP12 NTN1 FLRT2 FZD2 COL1A2

5.57e-0719316287865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B PRSS23 AKAP12 LRP1 IRAK3 DCBLD2 COL1A2

5.79e-0719416287b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 SYNE1 EML6 EXT1 PRSS23 MYOF C11orf96 COL1A2

6.50e-07197162885a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 SYNE1 EXT1 AKAP12 MPRIP MYOF C11orf96 COL1A2

6.50e-0719716289b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 SYNE1 EML6 EXT1 PRSS23 MYOF C11orf96 COL1A2

6.50e-071971628e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 MMP23B PRSS23 AKAP12 MYOF LRP1 MACF1 COL1A2

6.76e-0719816280a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 SYNE1 EXT1 AKAP12 MPRIP MYOF C11orf96 FLRT2

6.76e-071981628a860246bcea847249a78fd2e86ed8e04371060db
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL3A1 ABCA1 CYP11A1 CPA1 BCHE FLRT2 DCBLD2 COL1A2

7.02e-0719916288dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 MMP23B BCHE PRSS23 AKAP12 LRP1 MACF1 COL1A2

7.02e-071991628c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 MYO10 MMP23B AKAP12 MYOF LRP1 COL1A2

7.02e-071991628211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

COL3A1 ABCA1 MYO10 MMP23B AKAP12 MYOF LRP1 COL1A2

7.02e-0719916281a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 P4HA2 MMP23B BCHE LEPR AKAP12 LRP1 COL1A2

7.29e-07200162817ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 SYNE1 MMP23B PRSS23 MYOF LRP1 LRP4 COL1A2

7.29e-0720016289d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 MMP23B BCHE LEPR AKAP12 C11orf96 LRP1 COL1A2

7.29e-0720016282e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 P4HA2 MMP23B BCHE LEPR AKAP12 LRP1 COL1A2

7.29e-072001628665df8391d2ebcfc6536318612f4992852b5e2b8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL3A1 ABCA1 SYNE1 LEPR AKAP12 LRP1 FLRT2 COL1A2

7.29e-0720016280c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 P4HA2 MMP23B BCHE AKAP12 C11orf96 FERMT2 COL1A2

7.29e-07200162814f3fe19b6647b32a5e28d717235741997d8522c
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

P4HA2 ARHGAP24 RNASET2 LRP4 TRPV4 SEC13 COL1A2

1.15e-06147162787c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 MMP23B MFSD2B SYTL3 AGER FZD10

1.50e-06971626adda7a49b7754ed110e212346768bf52107c26fc
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 MMP23B MFSD2B SYTL3 AGER FZD10

1.50e-069716266d865ec3a413f595de17e0a5f8c61666ebb3e252
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 MMP23B MFSD2B SYTL3 AGER FZD10

1.50e-069716262cd5cafdf0a9a468baaafd4613d790fc048ee53e
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP23B PRSS23 LRP1 LRP4 ULK4 DCBLD2 COL1A2

3.03e-061701627d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellCOVID-19_Moderate-NK_CD56bright|World / disease group, cell group and cell class

IL12RB2 SYTL3 AGK EPS8L3 TTLL10 XKR5 ARAP2

3.03e-061701627caa6a534c1e9639caced9a51680f5c905f061bcc
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

P4HA2 ARHGAP24 LRP1 LRP4 TRPV4 SEC13 COL1A2

3.40e-061731627c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCellCOVID-19_Moderate-NK_CD56bright|COVID-19_Moderate / disease group, cell group and cell class

IL12RB2 CATSPER1 SYTL3 AGK EPS8L3 TTLL10 XKR5

3.40e-061731627a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL3A1 ABCA1 HEATR1 TNFSF11 IRAK3 CRYBG3 COL1A2

3.53e-061741627f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

IL12RB2 CATSPER1 ST6GALNAC5 AGK IRAK3 EPS8L3 TTLL10

4.25e-06179162790e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MMP23B PRSS23 AKAP12 FLRT2 FZD2 COL1A2

4.41e-061801627f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 RASGRF2 ST6GALNAC5 BUB1B NTN1 HS6ST3 ARAP2

4.92e-061831627e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA4 SPNS2 AKAP12 NTN1 OSBP2 FLRT2 DOCK6

4.92e-061831627bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL3A1 P4HA2 MMP23B LRP1 FLRT2 FZD2 COL1A2

5.10e-06184162701257e5c12e38b849fd3d9496c43ded666249ba5
ToppCellControl-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

IL12RB2 EXT1 IGF1R IRAK3 CDYL EPS8L3 TTLL10

5.28e-061851627520795866d44def5be3910ce8e728045c716a24d
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 CYP11A1 RTN4R IGF1R SYTL3 PRKACB DAPP1

5.28e-0618516275527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B AKAP12 IRAK3 NTN1 DCBLD2 COL1A2

5.28e-061851627d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL3A1 EPHB6 MMP23B CPA1 BCHE FLRT2 COL1A2

5.47e-0618616277812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 ARHGAP24 MMP23B COLGALT2 IGF1R NTN1 COL1A2

5.67e-061871627b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 ARHGAP24 MMP23B COLGALT2 IGF1R NTN1 COL1A2

5.67e-0618716279fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 ARHGAP24 MMP23B COLGALT2 IGF1R NTN1 COL1A2

5.67e-061871627e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP23B PRSS23 AKAP12 C11orf96 LRP1 NTN1 COL1A2

5.67e-0618716272c145e9d11424939dd99012a8cedf5d998b966e9
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B PRSS23 AKAP12 NTN1 FLRT2 COL1A2

5.87e-0618816276c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 SPNS2 SERINC2 AQP4 AKAP12 MYOF AGER

6.08e-061891627319e42f6e2322208de78bc666fb2c074707eb4da
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 SPNS2 SERINC2 AKAP12 CFAP65 MYOF AGER

6.29e-061901627050d6e0546954675b6adbfecb67854b1e09739d1
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 RTN4R MMP23B LEPR AKAP12 FLRT2 COL1A2

6.51e-0619116274b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

SAMD8 CALR MYOF BUB1B LRP1 LY75 KLHDC4

6.51e-0619116277bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

VMP1 IL12RB2 HEATR1 ALG10 MACF1 TYW1 TMEM68

6.51e-0619116279454f642c3621370fa23640b631301346b300950
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

COL3A1 COLGALT2 AKAP12 MYOF FLRT2 HS6ST3 COL1A2

6.51e-061911627156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 RTN4R MMP23B LEPR AKAP12 FLRT2 COL1A2

6.51e-06191162775d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

RASGRF2 MYO10 SPNS2 SYNE1 PRSS23 DOCK6 NOTCH4

6.51e-061911627c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 MMP23B PRSS23 AKAP12 MYOF IRAK3 DCBLD2

6.74e-06192162730cefa0990ba1f379f350bfbf994a78db145075e
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

RASGRF2 MYO10 SPNS2 SYNE1 PRSS23 DOCK6 NOTCH4

6.74e-0619216278a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 MMP23B IYD AKAP12 LRP1 FZD2 COL1A2

6.74e-06192162729bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 WSCD1 P4HA2 MMP23B PRSS23 FERMT2 COL1A2

6.74e-061921627be75783d9578974b662e1cb13bd3442a921fd50a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K14 EXT1 AKAP12 MYOF SYTL3 C11orf96 MACF1

6.74e-0619216278b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 MMP23B IYD AKAP12 LRP1 FZD2 COL1A2

6.74e-061921627cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 WSCD1 P4HA2 MMP23B PRSS23 FERMT2 COL1A2

6.74e-0619216274fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 BCHE C11orf96 LRP4 MACF1 HS6ST3 COL1A2

6.97e-061931627027e098ad018e782287f84eee0f77551018f2196
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSCD1 RASGRF2 SPNS2 COLGALT2 PRSS23 DOCK6 NOTCH4

6.97e-06193162788cd7d0d0da5c776b49fc131f746fe5ad9676fb7
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 BCHE C11orf96 LRP4 MACF1 HS6ST3 COL1A2

6.97e-061931627c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCellnormal-na-Lymphocytic_NK-NK_bright-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

IL12RB2 SYNE1 TNFSF11 SYTL3 AGK TTLL10 ARAP2

7.21e-061941627dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL3A1 BCHE COLGALT2 PRSS23 AKAP12 FLRT2 COL1A2

7.21e-061941627439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 BCHE COLGALT2 LEPR AKAP12 FLRT2 COL1A2

7.21e-06194162735b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCellnormal-na-Lymphocytic_NK-NK_bright|normal / PBMC cell types (v2) per disease, treatment status, and sex

IL12RB2 SYNE1 TNFSF11 SYTL3 AGK TTLL10 ARAP2

7.21e-0619416278c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCHE AKAP12 MYOF BCAP29 ST6GALNAC5 FERMT2 COL1A2

7.46e-061951627bd7526dd80a60ff7bc866e4f5a0e8acdbc10d191
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 EXT1 PRSS23 AKAP12 HS6ST3 DCBLD2 COL1A2

7.46e-061951627803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 EXT1 PRSS23 AKAP12 HS6ST3 DCBLD2 COL1A2

7.46e-0619516274f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 COLGALT2 LEPR AKAP12 LRP1 FLRT2 COL1A2

7.46e-061951627f54bc4454270ff06e85596f98199372b50d0179f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA1 MYO1C AQP4 AGER ST6GALNAC5 FZD2 ARAP2

7.71e-0619616276731fef8c148b6681d6ed38afdf23c8213e0bbbe
Drug8-N3cAMP

CALR PRKACA PRKACB PRKACG

2.23e-06141604CID006426627
Drug8-(6-aminohexyl)amino cyclic AMP

CYP11A1 PRKACA PRKACB PRKACG

2.23e-06141604CID000161999
Drug8-thiomethyl-cAMP

CYP11A1 PRKACA PRKACB PRKACG

8.39e-06191604CID000093140
Diseasecoronary artery disease (is_implicated_in)

ABCA1 WRN BCHE C1orf167 LEPR AGER

1.69e-051001586DOID:3393 (is_implicated_in)
Diseaseosteoporosis (is_implicated_in)

LEPR IGF1R TNFSF11 COL1A2

2.22e-05311584DOID:11476 (is_implicated_in)
Diseasemyocardial infarction (biomarker_via_orthology)

COL3A1 CASR REG1A REG1B IGF1R AGER FZD2

2.60e-051601587DOID:5844 (biomarker_via_orthology)
DiseaseHypercalcemia

CYP24A1 CASR TNFSF11

4.14e-05131583C0020437
DiseaseMilk-Alkali Syndrome

CYP24A1 CASR TNFSF11

4.14e-05131583C0026141
Diseasesleep duration, high density lipoprotein cholesterol measurement

ABCA1 TMEM94 JMJD1C ATP6V1H MACF1 DOCK6

4.96e-051211586EFO_0004612, EFO_0005271
Diseasehypercalcemia (is_implicated_in)

CYP24A1 CASR

8.52e-0531582DOID:12678 (is_implicated_in)
DiseaseColorectal Carcinoma

COL3A1 EPHB6 ABCA1 ABCA4 RASGRF2 CALR SYNE1 WRN AKAP12 BUB1B LRP1 TTLL10 DNAH8

1.10e-0470215813C0009402
DiseaseFibrosis

COL3A1 CHRNA1 LEPR COL1A2

1.50e-04501584C0016059
DiseaseCirrhosis

COL3A1 CHRNA1 LEPR COL1A2

1.50e-04501584C1623038
Diseasebrain ischemia (biomarker_via_orthology)

AQP4 AKAP12 AGER PRKACA PRKACB

2.27e-041021585DOID:2316 (biomarker_via_orthology)
DiseaseAlzheimer's disease (implicated_via_orthology)

IGF1R AGER LRP1 NOTCH4

2.51e-04571584DOID:10652 (implicated_via_orthology)
DiseaseGranulosa Cell Cancer

DICER1 LEPR

2.82e-0451582C1567257
DiseaseEhlers-Danlos Syndrome

COL3A1 COL1A2

2.82e-0451582C0013720
DiseasePancreatic Diseases

LEPR AGER

4.21e-0461582C0030286
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

ABCA1 SPG11 JMJD1C MACF1

4.67e-04671584EFO_0008595, EFO_0020946
DiseaseHyperglycemia, Postprandial

COL3A1 LEPR AGER

5.50e-04301583C1855520
DiseaseHyperglycemia

COL3A1 LEPR AGER

5.50e-04301583C0020456
Diseaselithostathine-1-alpha measurement

REG1A REG1B

5.88e-0471582EFO_0801083
Diseasecoiled-coil domain-containing protein 126 measurement

ABCA1 BCHE

5.88e-0471582EFO_0801482
Diseaseobsolete_interleukin-1 alpha measurement

REG1A REG1B

5.88e-0471582EFO_0802653
DiseaseHereditary pancreatitis

CPA1 CASR

5.88e-0471582C0238339
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF FER1L5

5.88e-0471582DOID:11724 (implicated_via_orthology)
Diseasegallbladder cancer (is_marker_for)

CALR BUB1B

5.88e-0471582DOID:3121 (is_marker_for)
Diseasefatty acid measurement

ABCA1 ABCA4 MYO10 JMJD1C FZD9 TYW1B MACF1 DOCK6 NOTCH4

5.98e-044361589EFO_0005110
DiseaseOvarian Mucinous Adenocarcinoma

EPHB6 MAP3K14 HCK

6.06e-04311583C1335167
Diseaseschizophrenia (is_implicated_in)

RTN4R AGER TRPV3 NOTCH4

8.30e-04781584DOID:5419 (is_implicated_in)
Diseasecolon cancer (is_implicated_in)

CALR CHAF1A CYP24A1

9.45e-04361583DOID:219 (is_implicated_in)
Diseasepancreatitis (implicated_via_orthology)

CPA1 LEPR

1.00e-0391582DOID:4989 (implicated_via_orthology)
DiseaseEhlers-Danlos syndrome (is_implicated_in)

COL3A1 COL1A2

1.00e-0391582DOID:13359 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABCA1 SPG11 JMJD1C LEPR TYW1B MACF1 DOCK6

1.01e-032911587EFO_0008317, EFO_0020946
Diseasetype 1 diabetes mellitus (is_implicated_in)

BCHE REG1A AGER NOTCH4

1.14e-03851584DOID:9744 (is_implicated_in)
Diseaseneuroblastoma (is_implicated_in)

CHAF1A IGF1R

1.25e-03101582DOID:769 (is_implicated_in)
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

ABCA1 SPG11 JMJD1C TYW1B MACF1 SAMM50

1.38e-032251586EFO_0008317, EFO_0020947
Diseaseserum albumin measurement

VMP1 CYP11A1 MAP3K14 SKIDA1 BCHE JMJD1C LEPR MACF1 XKR5 NOTCH4

1.38e-0359215810EFO_0004535
DiseaseDegenerative polyarthritis

AGER DAPP1 TRPV4 COL1A2

1.60e-03931584C0029408
DiseaseOsteoarthrosis Deformans

AGER DAPP1 TRPV4 COL1A2

1.60e-03931584C0086743
Diseasedementia (is_implicated_in)

IGF1R NOTCH4

1.82e-03121582DOID:1307 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

P4HA2 ABCA1 JMJD1C TYW1B MACF1 SAMM50

1.87e-032391586EFO_0008317, EFO_0020945
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

AQP4 IGF1R

2.14e-03131582DOID:332 (biomarker_via_orthology)
DiseaseWeight Gain

STIM2 MYO10 LEPR MPRIP

2.24e-031021584C0043094
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

SPG11 JMJD1C LRP4 MACF1

2.32e-031031584EFO_0008595, EFO_0020944
Diseasesuperior frontal gyrus grey matter volume measurement

STIM2 RASGRF2

2.49e-03141582EFO_0006516
Diseaseurokinase plasminogen activator surface receptor measurement

LY75 DCBLD2

2.49e-03141582EFO_0010932
Diseasechronic kidney disease (is_implicated_in)

AKAP12 AGER

2.49e-03141582DOID:784 (is_implicated_in)
Diseaseplatelet component distribution width

COL3A1 VMP1 SYNE1 SIN3A JMJD1C C2CD5 MPRIP FAM187B IGF1R DAPP1 MACF1

2.58e-0375515811EFO_0007984
Diseaseresponse to simvastatin, total cholesterol change measurement, response to fenofibrate

ZNF775 KCNH8 TRIOBP

2.60e-03511583EFO_0007806, GO_1901557, GO_1903491
Diseasecortical thickness

VMP1 P4HA2 ABCA4 CHAF1A TRIOBP EXT1 JMJD1C FZD9 IGF1R TNFSF11 LRP1 LRP4 MACF1 TMEM131

2.72e-03111315814EFO_0004840
Diseasequinate measurement

NOX5 LEPR

2.86e-03151582EFO_0021167
DiseaseRhabdomyosarcoma

DICER1 BUB1B

2.86e-03151582C0035412
DiseaseSchizophrenia

COL3A1 ABCA1 RTN4R AQP4 DICER1 SBNO2 CFAP65 SLC38A2 AGER LRP1 ULK4 NOTCH4

2.94e-0388315812C0036341
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ABCA1 SPG11 JMJD1C TYW1B LRP4 MACF1

3.07e-032641586EFO_0008317, EFO_0020944
Diseasemyopia (is_implicated_in)

P4HA2 CPSF1

3.25e-03161582DOID:11830 (is_implicated_in)
Diseasediabetic retinopathy (implicated_via_orthology)

AQP4 AGER

3.25e-03161582DOID:8947 (implicated_via_orthology)
Diseasethyroid volume

FAM227B IGF1R

3.25e-03161582EFO_0004865
Diseaseurate measurement

VMP1 P4HA2 ABCA1 EXT1 SIN3A JMJD1C FZD9 IGF1R LRP1 LRP4 HS6ST3 TECPR1

3.27e-0389515812EFO_0004531
DiseaseRenal Insufficiency

CYP24A1 LEPR

3.68e-03171582C1565489
Diseaserenal fibrosis (implicated_via_orthology)

LEPR AGER

3.68e-03171582DOID:0050855 (implicated_via_orthology)
DiseaseAlzheimer's disease (biomarker_via_orthology)

IGF1R AGER LRP1

3.75e-03581583DOID:10652 (biomarker_via_orthology)
Diseaseomega-3 polyunsaturated fatty acid measurement

ABCA1 JMJD1C TYW1B DOCK6

3.78e-031181584EFO_0010119
Diseasecolon cancer (is_marker_for)

CALR CHAF1A CYP24A1

3.93e-03591583DOID:219 (is_marker_for)
Diseasealcohol use disorder (implicated_via_orthology)

JMJD1C CHRNA1 PRKACA PRKACB PRKACG

4.08e-031951585DOID:1574 (implicated_via_orthology)
Diseaseserum amyloid A-1 protein measurement

BCHE LEPR

4.12e-03181582EFO_0008282
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

LEPR SAMM50

4.12e-03181582DOID:0080208 (is_implicated_in)
DiseaseAbnormality of chromosome segregation

MYO10 FZD9 HS6ST3

4.12e-03601583HP_0002916
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

SPG11 JMJD1C LRP4 MACF1

4.14e-031211584EFO_0008595, EFO_0020943
Diseasecolorectal cancer (is_implicated_in)

CYP24A1 DICER1 BUB1B TRPV3

4.14e-031211584DOID:9256 (is_implicated_in)
DiseasePost-Traumatic Osteoporosis

CYP24A1 TNFSF11 COL1A2

4.32e-03611583C0751406
DiseaseOsteoporosis, Senile

CYP24A1 TNFSF11 COL1A2

4.32e-03611583C0029459
DiseaseOsteoporosis, Age-Related

CYP24A1 TNFSF11 COL1A2

4.32e-03611583C0001787
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

SPG11 JMJD1C FZD9 TYW1B MACF1

4.54e-032001585EFO_0004611, EFO_0020945
Diseaseosteoporosis (implicated_via_orthology)

ATP6V1H IRAK3

4.59e-03191582DOID:11476 (implicated_via_orthology)
DiseaseOsteoporosis

CYP24A1 TNFSF11 COL1A2

4.73e-03631583C0029456
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

SPG11 JMJD1C LRP4 MACF1

4.91e-031271584EFO_0008595, EFO_0020947
Diseasedocosahexaenoic acid measurement

ABCA1 JMJD1C DOCK6 KAT14

4.91e-031271584EFO_0007761
Diseaseatherosclerosis (biomarker_via_orthology)

CASR AGER

5.08e-03201582DOID:1936 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
TTSWEDKLKLAHFAW

URB2

16

Q14146
KEHLQVFWDGSFWKL

BUB1B

966

O60566
FKGVWTQAFWKAVTA

AQP4

26

P55087
QKGFWIHWKLKELST

FAM227B

296

Q96M60
HWKKTTAGLCLLTWG

AGK

11

Q53H12
AAGRWAFKKWHQRLA

C1orf167

1406

Q5SNV9
AARWHQKDSGSVWKV

ARSD

466

P51689
SLTKWSDIWNATKYA

BCHE

76

P06276
GHSTNLFQWLWEKLT

CATSPER1

416

Q8NEC5
KVALWTEHGQFRQKW

CRYBG3

2906

Q68DQ2
KVWFNNKGWHALVSF

ABCA4

1616

P78363
QKVVLKDLWKHSFSW

BRDT

36

Q58F21
TQGWAGWRKKTSFRK

AKAP12

301

Q02952
FEAKIPTSFHRKWWG

CASR

706

P41180
REWVTQASGVWFAKK

CPA1

181

P15085
AILSGWKTFWQSVSK

FBXO4

26

Q9UKT5
KVWFNNKGWHAISSF

ABCA1

1591

O95477
WGKIATFWNKAFLTI

BCAP29

41

Q9UHQ4
AVVTGLVHKWAWTKD

ACSF3

221

Q4G176
QWRKGWFAMDKSSLH

ARAP2

1031

Q8WZ64
EAQRWKDSWKQSLHT

CCDC180

1681

Q9P1Z9
WGTWNKKTALIRARD

CHAF1A

571

Q13111
ASWTKERWNQEFTKH

DICER1

131

Q9UPY3
TKWPSHGAFFLKSWL

FLRT2

6

O43155
DWDYGKWRSSSSHKR

CLK1

16

P49759
KAGDWWKFTVNIISV

NTN1

506

O95631
TGSWDKTLKFWDTRS

RAE1

146

P78406
WKLNTGRTEAWKVLS

AGER

51

Q15109
KDTIWLHIRSQGQWT

NOX5

501

Q96PH1
WVIKESRGWKHSVTY

CHRNA1

196

P02708
DIKNHKWFATTDWIA

PRKACA

291

P17612
KWLKGLHQGTRAWAS

KIAA0100

846

Q14667
GQWKKHWFVLADQSL

MPRIP

401

Q6WCQ1
LHAAATVIKRAWQKW

MYO19

806

Q96H55
WTDWETKSINRAHKT

LRP1

3246

Q07954
LHWKGWELGKETTRN

CFAP65

151

Q6ZU64
HILWLKDYKNSSNWK

JMJD1C

2166

Q15652
SKLHLYKGSWSDWSE

IL12RB2

296

Q99665
KSVVWENKHITWFAT

CPSF1

1326

Q10570
LWDWDHRNLTIKAGK

IGF1R

431

P08069
TFLLGNRKKTSTWWS

KAT14

161

Q9H8E8
NDWTDGIFSTLWRKT

DNAH8

2176

Q96JB1
DHSKRWWLVKNEAGR

EPS8L3

481

Q8TE67
GFWIWSGKTLHSWRK

FZD2

536

Q14332
WFRSKQEALKQGWLH

MYO10

1206

Q9HD67
WSDGKRLHFSRWAET

LY75

1176

O60449
WSEDVGNHTKFTFLW

LEPR

691

P48357
WEWVLQRFGKKTSAF

MFSD2B

336

A6NFX1
KSGTRELLWSWAQKN

IRAK3

66

Q9Y616
NRSKSEEDWKTRWFH

OSBPL1A

906

Q9BXW6
FSKHGWSLWQEITIS

OSBP2

636

Q969R2
KKETWLFSRFSTGWS

HS6ST3

191

Q8IZP7
YLSEWKHVQRGATWK

HS6ST3

251

Q8IZP7
SLHSFDRKWGQIQKW

LRRFIP2

61

Q9Y608
HWSTLRHWLSDVKDK

MACF1

1196

Q9UPN3
KWVSNKWFHERGQEF

P4HA2

511

O15460
LRKQGGFVKTWHTRW

ARHGAP24

26

Q8N264
GFVKTWHTRWFVLKG

ARHGAP24

31

Q8N264
LLASKVWRNHGLWSV

CCNYL3

126

P0C7X3
TLTWFLAAGKKWGHE

FZD10

331

Q9ULW2
LTWFLAAGKKWGHEA

FZD9

336

O00144
WYRSSKDKKHVWLGE

COL1A2

1216

P08123
SGEWWKARSLATRKE

HCK

111

P08631
DIKTHKWFATTDWIA

PRKACB

291

P22694
DIKNHKWFATTSWIA

PRKACG

291

P22612
WFSTSFKTWKESQRD

KLRF2

91

D3W0D1
QRMWSHFWKVSTQGL

BFAR

391

Q9NZS9
VRWRKSVTHWKQTSD

DOCK6

1351

Q96HP0
NSKERWGYTSKWTND

EXT1

601

Q16394
SHRSAWGKSRKKNWQ

CDYL

6

Q9Y232
KVWQDHTLAWDTIFK

CYP24A1

266

Q07973
TFKAFKVGTERWWLD

GLT6D1

131

Q7Z4J2
ILANHWVAKKIWESF

DIS3L

686

Q8TF46
QWLLHATSKEKEWVS

C4orf17

201

Q53FE4
GLVKTWKTRWFTLHR

DAPP1

176

Q9UN19
DGWTSRWIESKHKSD

CALR

31

P27797
RLFRTKTWKDHVAAW

CYP11A1

256

P05108
TWLEKKWGHNITEFQ

ERO1A

271

Q96HE7
WKKKRYSHGGTSWRV

FBXO40

621

Q9UH90
WVLHLATKTWEQVKS

KLHDC4

156

Q8TBB5
PRKHWWTDSSAEKKH

COL3A1

1311

P02461
SKHRWFWLLPVKQSG

HEATR1

156

Q9H583
KLRGFWLSQWKKDHS

MECR

306

Q9BV79
HSIVFWDWKKGEKIA

EML6

796

Q6ZMW3
WDWKKGEKIATTRGH

EML6

801

Q6ZMW3
ETLHLGSKQLIFTWW

FAM187B

131

Q17R55
AWHWRNRKKKTEGTY

DCBLD2

551

Q96PD2
KEHAAIILWNTTSWK

ELP2

591

Q6IA86
LLGKWFDKWTDSQRR

FBXO16

41

Q8IX29
WLLKTHWTLDKYGIQ

FERMT2

71

Q96AC1
DWDRTHAWKSRKQSR

COLGALT2

586

Q8IYK4
KTSHTVKWEGVWREL

SAMM50

221

Q9Y512
TRKKRSQGLHWSHWQ

SCP2D1-AS1

76

Q9BR46
WWAEIRQEIKSHAKA

C2CD5

391

Q86YS7
KGDSARKWEWLHESK

AUNIP

191

Q9H7T9
RKWEWLHESKKNYQS

AUNIP

196

Q9H7T9
HGALTESKRWSKIWL

FADS6

106

Q8N9I5
KKNRRWHWSSGSLVS

REG1A

106

P05451
KKNRRWHWSSGSLVS

REG1B

106

P48304
GHRWVTDLKKLRTNW

IYD

166

Q6PHW0
SFAWSWRVKHGQLEN

MAP3K14

931

Q99558
RQEVSRIHKGWKEWS

GPR132

316

Q9UNW8
DFKWVDKSVSSLFWS

GPRASP1

191

Q5JY77
LWAWLQKFRGSSSEV

RTN4R

271

Q9BZR6
KLLHKFNDVVWHVSW

SEC13

256

P55735
LRWKGAKNTDWEHKE

SYTL3

46

Q4VX76
IANITHSTFLWLKWR

TAS2R41

111

P59536
WSPVHKSEKFWRENA

ATP6V1H

366

Q9UI12
HWQRLEKELSSFLTW

SYNE1

1656

Q8NF91
RWTTKHVAVWLKDEG

SAMD8

11

Q96LT4
KPWGSHTTTLKAKAW

SAMD7

261

Q7Z3H4
HFSLFKKKTVTGWWP

FER1L5

1871

A0AVI2
WKKGVWLTDLVHVAA

MMP23B

196

O75900
FWSQRKITKAREWFH

PRPF6

851

O94906
KKTAEASRWHEKWFA

RASGRF2

31

O14827
KWERKIIGIFSGHQW

PRSS23

331

O95084
SWHLKRWTKVDTIAA

EPHB6

146

O15197
GLSSLWRLFRGKKWN

PIGQ

416

Q9BRB3
RKKHWSASWTVLEGG

ARHGAP27

516

Q6ZUM4
FWKDKHQLWRGLSGA

SKIDA1

131

Q1XH10
LHQRFQAWVDKWTKE

SIN3A

1206

Q96ST3
LESRKSLWGQFWSAH

SBNO2

526

Q9Y2G9
GKDRKISNTWLSTGW

ST6GALNAC5

221

Q9BVH7
SVKQAAGDWHWALRV

SPNS2

251

Q8IVW8
LVKTGWRSWHLGFWK

OCSTAMP

11

Q9BR26
TGKDQTESWWKAFSR

WRN

1006

Q14191
FSTVWLSWDIQGKKF

SRPK1

91

Q96SB4
DKWGKTALHWAAAVN

NOTCH4

1731

Q99466
REIDKAEGKFWTHWN

SF3A2

186

Q15428
AEGKFWTHWNRETKQ

SF3A2

191

Q15428
QWKKHWFVLTDSSLK

TRIOBP

1806

Q9H2D6
GWSIADSLKSKSIFW

ALG10

381

Q5BKT4
STWIKLTFVHGGKWT

CCDC54

246

Q8NEL0
FKWHSLSSELRAVWA

C11orf96

196

Q7Z7L8
WSLKQARIDFWKKCH

SPG11

1721

Q96JI7
STSLTFHWKLWGRHR

SENP3

141

Q9H4L4
NRSRFWKHEWEKHGT

RNASET2

106

O00584
TGDWEGRWNHVKKFL

UBA3

31

Q8TBC4
TWLLTAAHCFWKNKD

TMPRSS11F

241

Q6ZWK6
HFLCTSSWDKNLKIW

WDR88

286

Q6ZMY6
HNLWDGARKTVATLW

TMEM68

86

Q96MH6
TWKEVWRSSFLHHSN

TMEM94

46

Q12767
KRWKTSEVHNWTLED

STIM2

126

Q9P246
KDFSWWRHSLITVSI

SLC38A2

406

Q96QD8
VTKDWKVWFRRGVNS

TECPR1

306

Q7Z6L1
WDLHQSLFKGWTGIK

TMEM131

781

Q92545
FWQGVKSKVTALCWH

GEMIN5

421

Q8TEQ6
DCGKRFSWWSSLKIH

ZNF775

111

Q96BV0
TRHKAFLKAWPWQNS

TTTY12

6

Q9BZ98
LKHAGKWSLRWFLSP

nan

61

Q6ZVQ6
RESSGWVSWKCHLKA

nan

696

Q3C1V9
KVSLSSWYHDRGWAK

TNFSF11

181

O14788
KWKGLALSQRALHWN

ZNF852

21

Q6ZMS4
EVKWTEWKTHVSFLN

TRPV3

736

Q8NET8
QKASAGTAKWAWLRR

TTC37

556

Q6PGP7
AHRKFKIGGEWWTWI

TYW1

656

Q9NV66
WSSHVLDWLKYGKRL

WSCD1

471

Q658N2
WATHTLDWLKFGKKV

WSCD2

461

Q2TBF2
LGVWKRHWDAALTSL

XKR5

76

Q6UX68
LSTQKRDKIWNFHVW

TGM7

326

Q96PF1
FWKARGLAKDWVFTT

TTLL10

451

Q6ZVT0
EWKQVHGETRKSWKA

WDR87

1466

Q6ZQQ6
SKESKHIWKLQWATT

TRPV4

726

Q9HBA0
FAHSWNQRWLGKAEE

SERINC2

181

Q96SA4
WWGKQALKESQFTLS

GTF2H3

21

Q13889
IAHRKFKIGGEWWTW

TYW1B

591

Q6NUM6
WTRLLQHSFWKKAFA

ULK4

271

Q96C45
KEWTSKLWHRQSIVV

VMP1

66

Q96GC9
HFSTFKAGWDWLILL

KCNH8

216

Q96L42
FWTDWGHIAKIERAN

LRP4

1486

O75096
SLATKIQAAWRGFHW

MYO1C

736

O00159
LIGWKFHWKQRSSDT

MYOF

1056

Q9NZM1