Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium-dependent ATPase activity	MYH6 ATP2A1 ATP2B2	6.30e-06	4	234	3	GO:0030899
GeneOntologyMolecularFunction	D-dopachrome decarboxylase activity	DDT DDTL	1.37e-04	2	234	2	GO:0033981
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2B TLR9 KDM2A	1.79e-04	10	234	3	GO:0045322
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2A1 ATP2A2 ATP2B2	2.45e-04	11	234	3	GO:0005388
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXND1 PLXNA3 PLXNA4	3.23e-04	12	234	3	GO:0017154
GeneOntologyMolecularFunction	phenylpyruvate tautomerase activity	DDT DDTL	4.07e-04	3	234	2	GO:0050178
GeneOntologyMolecularFunction	dopachrome isomerase activity	DCT DDT	4.07e-04	3	234	2	GO:0004167
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH6 MYO18B DYNC1H1 KIF22 DNHD1 DNAH12 KIF18B	4.86e-04	118	234	7	GO:0003774
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PCYT1A MYLK PLK5 DGKH CHUK MAST4 SGMS1 BRAF MAP3K9 POLR1B ULK1 GMPPB PIGO MOK POLR2A PARP3 KSR2 HIPK3 PALS1 RPAP1 FLAD1 SRPK3 MAP2K5	6.93e-04	938	234	23	GO:0016772
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	DDT DDTL	8.08e-04	4	234	2	GO:0016862
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST4 NDST3	8.08e-04	4	234	2	GO:0015016
GeneOntologyMolecularFunction	N-acetylglucosamine deacetylase activity	NDST4 NDST3	8.08e-04	4	234	2	GO:0050119
GeneOntologyMolecularFunction	dynein intermediate chain binding	SPTBN5 DYNC1H1 DNHD1 DNAH12	8.96e-04	37	234	4	GO:0045505
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC1H1 DNHD1 DNAH12	1.14e-03	18	234	3	GO:0008569
GeneOntologyMolecularFunction	MAP kinase kinase activity	BRAF MAP3K9 MAP2K5	1.14e-03	18	234	3	GO:0004708
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, transposing C=C bonds	DCT DDT EHHADH	1.34e-03	19	234	3	GO:0016863
GeneOntologyMolecularFunction	microtubule motor activity	DYNC1H1 KIF22 DNHD1 DNAH12 KIF18B	1.38e-03	70	234	5	GO:0003777
Domain	IG_FLMN	AREL1 FLNB FLNC TRIM45	4.36e-06	10	229	4	SM00557
Domain	Ig_E-set	PLXND1 AREL1 A2ML1 PKHD1 PLXNA3 FLNB FLNC TRIM45 PLXNA4	5.36e-06	104	229	9	IPR014756
Domain	Filamin	AREL1 FLNB FLNC TRIM45	6.79e-06	11	229	4	PF00630
Domain	FILAMIN_REPEAT	AREL1 FLNB FLNC TRIM45	6.79e-06	11	229	4	PS50194
Domain	Filamin/ABP280_rpt	AREL1 FLNB FLNC TRIM45	6.79e-06	11	229	4	IPR001298
Domain	Filamin/ABP280_repeat-like	AREL1 FLNB FLNC TRIM45	6.79e-06	11	229	4	IPR017868
Domain	-	GP6 MYLK DAG1 IL20RA PLXND1 UNC5A AREL1 PKHD1 PLXNA3 FLNB FLNC DSCAM CILP IFNLR1 TRIM45 LRRN4CL ERMAP PLXNA4 MYOM2 IGSF1 CXADR	7.12e-05	663	229	21	2.60.40.10
Domain	TSP_1	UNC5A CILP ADAMTS5 ADAMTS12 CCN1 ADAMTSL2	1.21e-04	63	229	6	PF00090
Domain	TSP1	UNC5A CILP ADAMTS5 ADAMTS12 CCN1 ADAMTSL2	1.44e-04	65	229	6	SM00209
Domain	TSP1_rpt	UNC5A CILP ADAMTS5 ADAMTS12 CCN1 ADAMTSL2	1.44e-04	65	229	6	IPR000884
Domain	TSP1	UNC5A CILP ADAMTS5 ADAMTS12 CCN1 ADAMTSL2	1.44e-04	65	229	6	PS50092
Domain	Plexin_cytopl	PLXND1 PLXNA3 PLXNA4	1.45e-04	9	229	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNA3 PLXNA4	1.45e-04	9	229	3	IPR013548
Domain	Plexin	PLXND1 PLXNA3 PLXNA4	1.45e-04	9	229	3	IPR031148
Domain	Wnt7	WNT7A WNT7B	1.50e-04	2	229	2	IPR013300
Domain	Ig-like_fold	GP6 MYLK DAG1 IL20RA PLXND1 UNC5A AREL1 PKHD1 PLXNA3 FLNB FLNC DSCAM CILP IFNLR1 TRIM45 LRRN4CL ERMAP PLXNA4 MYOM2 IGSF1 CXADR	1.70e-04	706	229	21	IPR013783
Domain	Hydrolase_3	ATP2A1 ATP2A2 ATP2B2	2.05e-04	10	229	3	PF08282
Domain	IPT	PLXND1 PKHD1 PLXNA3 PLXNA4	3.10e-04	27	229	4	SM00429
Domain	Macrophage_inhib_fac	DDT DDTL	4.45e-04	3	229	2	PD004816
Domain	Macrophage_inhib_fac_CS	DDT DDTL	4.45e-04	3	229	2	IPR019829
Domain	Tautomerase/MIF_sf	DDT DDTL	4.45e-04	3	229	2	IPR014347
Domain	MIF	DDT DDTL	4.45e-04	3	229	2	PS01158
Domain	Tyr_Pase_KIM-con	PTPN7 PTPRR	4.45e-04	3	229	2	IPR008356
Domain	P-type_ATPase_IIA	ATP2A1 ATP2A2	4.45e-04	3	229	2	IPR005782
Domain	Macrophage_inhib_fac	DDT DDTL	4.45e-04	3	229	2	IPR001398
Domain	MIF	DDT DDTL	4.45e-04	3	229	2	PF01187
Domain	PDZ	PTPN4 MAST4 LRRC7 PREX1 HTRA3 PALS1 SCRIB PDZRN3	4.89e-04	148	229	8	SM00228
Domain	TIG	PLXND1 PKHD1 PLXNA3 PLXNA4	5.34e-04	31	229	4	PF01833
Domain	-	PTPN4 MAST4 LRRC7 PREX1 HTRA3 PALS1 SCRIB PDZRN3	5.35e-04	150	229	8	2.30.42.10
Domain	PDZ	PTPN4 MAST4 LRRC7 PREX1 HTRA3 PALS1 SCRIB PDZRN3	5.59e-04	151	229	8	PS50106
Domain	PDZ	PTPN4 MAST4 LRRC7 PREX1 HTRA3 PALS1 SCRIB PDZRN3	5.84e-04	152	229	8	IPR001478
Domain	Dynein_heavy_dom-2	DYNC1H1 DNHD1 DNAH12	5.99e-04	14	229	3	IPR013602
Domain	DHC_N2	DYNC1H1 DNHD1 DNAH12	5.99e-04	14	229	3	PF08393
Domain	IPT	PLXND1 PKHD1 PLXNA3 PLXNA4	6.05e-04	32	229	4	IPR002909
Domain	DHC_fam	DYNC1H1 DNHD1 DNAH12	7.42e-04	15	229	3	IPR026983
Domain	Dynein_heavy	DYNC1H1 DNHD1 DNAH12	7.42e-04	15	229	3	PF03028
Domain	Dynein_heavy_dom	DYNC1H1 DNHD1 DNAH12	7.42e-04	15	229	3	IPR004273
Domain	Rho_GTPase_activation_prot	PLXND1 NF1 PLXNA3 OCRL ARHGAP39 PLXNA4	7.47e-04	88	229	6	IPR008936
Domain	G8_domain	PKHD1 CEMIP	8.84e-04	4	229	2	IPR019316
Domain	G8	PKHD1 CEMIP	8.84e-04	4	229	2	PS51484
Domain	Heparan_SO4_deacetylase	NDST4 NDST3	8.84e-04	4	229	2	IPR021930
Domain	G8	PKHD1 CEMIP	8.84e-04	4	229	2	SM01225
Domain	G8	PKHD1 CEMIP	8.84e-04	4	229	2	PF10162
Domain	HSNSD	NDST4 NDST3	8.84e-04	4	229	2	PF12062
Domain	ATPase_P-typ_TM_dom	ATP2A1 ATP2A2 ATP2B2	9.05e-04	16	229	3	IPR023298
Domain	-	ATP2A1 ATP2A2 ATP2B2	9.05e-04	16	229	3	1.20.1110.10
Domain	ATPase_P-typ_cation-transptr_C	ATP2A1 ATP2A2 ATP2B2	1.09e-03	17	229	3	IPR006068
Domain	Cation_ATPase_C	ATP2A1 ATP2A2 ATP2B2	1.09e-03	17	229	3	PF00689
Domain	Cation_ATPase_N	ATP2A1 ATP2A2 ATP2B2	1.30e-03	18	229	3	PF00690
Domain	IB	HTRA3 IGFBP5 CCN1	1.30e-03	18	229	3	SM00121
Domain	Cation_ATPase_N	ATP2A1 ATP2A2 ATP2B2	1.30e-03	18	229	3	SM00831
Domain	Wnt	WNT16 WNT7A WNT7B	1.52e-03	19	229	3	IPR005817
Domain	WNT1	WNT16 WNT7A WNT7B	1.52e-03	19	229	3	PS00246
Domain	Wnt_CS	WNT16 WNT7A WNT7B	1.52e-03	19	229	3	IPR018161
Domain	wnt	WNT16 WNT7A WNT7B	1.52e-03	19	229	3	PF00110
Domain	ATPase_P-typ_cation-transptr_N	ATP2A1 ATP2A2 ATP2B2	1.52e-03	19	229	3	IPR004014
Domain	WNT1	WNT16 WNT7A WNT7B	1.52e-03	19	229	3	SM00097
Domain	IGFBP	HTRA3 IGFBP5 CCN1	1.78e-03	20	229	3	PF00219
Domain	IGFBP-like	HTRA3 IGFBP5 CCN1	1.78e-03	20	229	3	IPR000867
Domain	IGFBP_N_2	HTRA3 IGFBP5 CCN1	1.78e-03	20	229	3	PS51323
Domain	PDZ	PTPN4 MAST4 LRRC7 HTRA3 PALS1 SCRIB PDZRN3	1.79e-03	141	229	7	PF00595
Domain	Pectin_lyas_fold	PKHD1 CEMIP	2.17e-03	6	229	2	IPR012334
Domain	-	PKHD1 CEMIP	2.17e-03	6	229	2	2.160.20.10
Domain	WxxW_domain	CILP CEMIP	2.17e-03	6	229	2	IPR025155
Domain	Mucin2_WxxW	CILP CEMIP	2.17e-03	6	229	2	PF13330
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 USP34 HIVEP2 KMT2B PFAS PLXND1 PHLDB1 NAV1 CACNA1H ULK1 PPP2R3C PREX1 MED12 FOXK1 DYNC1H1 PLXNA3 FLNC CRYBG2 WNT7B POLR2A KSR2 AKNA RASSF7 IFNLR1 SBNO2 THADA RPAP1 ZNF592 RAI1	7.09e-10	1105	238	29	35748872
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KMT2B MYLK DAG1 PTPN4 POLR1B MYO18B KIF22 CACNA1F FLNB FLNC PCDHA11 PCDHA5 TLR9 CELF2 CHRD MAP2K5	1.30e-09	329	238	16	17474147
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SGSM1 KMT2B PIDD1 DGKH HNRNPL PKHD1 MAP3K9 LRRC7 DYNC1H1 CFAP47 CACNA1F FLNB COPG1 POLR2A MUC19 PCARE PCDHA5 RPAP1 ZNF592 PLXNA4 CHRD SCRIB RAI1	1.82e-09	736	238	23	29676528
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 KDM5C SANBR PLXND1 MAST4 MTUS1 TMEM131L PLAGL2 FTO AKNA ZNF592 MDC1 HHIPL1 IGSF1 ANKS3 RAI1	8.97e-07	529	238	16	14621295
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 GON4L UNC5A PHLDB1 NAV1 CACNA1H LRRC7 ULK1 TET3 DYNC1H1 RPAP1 ACIN1 SUZ12 SCRIB	9.82e-07	407	238	14	12693553
Pubmed	SERCA1a can functionally substitute for SERCA2a in the heart.	MYH6 ATP2A1 ATP2A2	1.26e-06	4	238	3	9887021
Pubmed	Association of regions on chromosomes 6 and 7 with blood pressure in Nigerian families.	HDAC9 CPED1 PRKN	1.26e-06	4	238	3	20031566
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SGSM1 HIVEP2 ZBTB20 DGKH MDM4 DDT HNRNPL AFMID PTPN4 PHLDB1 SGMS1 PTPRR NAV1 CACNA1H LRRC7 TET3 MAML3 COL5A1 FLNB WNT7B KSR2 ARHGAP39 SBNO2 HIPK3 THADA PRKN KDM2A RAI1	1.43e-06	1489	238	28	28611215
Pubmed	Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.	CILP IGFBP5 SRPK3 ATP2A1 ATP2A2	2.11e-06	31	238	5	16140986
Pubmed	A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.	DAG1 GON4L SPTBN5 SPATA17 NF1 GMPPB WWC1 KNL1 HIGD2A C4orf54 KDM2A RPA2	3.46e-06	331	238	12	19490893
Pubmed	MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model.	DCT DDT DDTL	6.23e-06	6	238	3	34850744
Pubmed	Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury.	BRAF WNT7A WNT7B	6.23e-06	6	238	3	33086038
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HDAC9 PFAS ELFN2 KRBA1 ELAPOR1 PREX1 MAML3 MED12 RNF169 ARHGAP39 THADA KDM2A PDZRN3 ADAMTSL2	8.92e-06	493	238	14	15368895
Pubmed	MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms.	DCT DDT DDTL	1.09e-05	7	238	3	28539339
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DDX59 GON4L NAV1 MED26 MED12 KIF22 TCEA1 FLNB RNF169 POLR2A ZNF592 KDM2A SUZ12 SCRIB KIF18B RAI1	1.11e-05	645	238	16	25281560
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	SUSD3 IL20RA CPED1 GASK1B NDST3 ELAPOR1 GMPPB PIGO DNHD1 CILP PAMR1 SHISA2 TLR9 PRSS58 ADAMTS12 LRRN4CL PLXNA4 CHRD SARAF HHIPL1	1.68e-05	985	238	20	12975309
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2A1 ATP2A2 ATP2B2	1.73e-05	8	238	3	10951186
Pubmed	C3G regulates the size of the cerebral cortex neural precursor population.	BRAF WNT7A WNT7B	1.73e-05	8	238	3	16858399
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B KDM5C NF1 BRAF TCEA1 RNF169 ZEB1 POLR2A ARHGAP39 RPAP1 ZNF592 MDC1 ACIN1 SUZ12 SCRIB ATP2A2 CXADR	2.78e-05	774	238	17	15302935
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXND1 UNC5A PLXNA3 DSCAM PLXNA4	2.88e-05	52	238	5	26633812
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 USP34 DCDC1 KDM5C SUCLG1 MTUS1 FOXK1 WWC1 KNL1 POLR2A ECT2L EDEM3 THADA ZNF592 TRAF3IP3 SUZ12 SCRIB KIF18B PDZRN3 ANKS3 RAI1	3.14e-05	1116	238	21	31753913
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2B TET3 KDM2A	3.66e-05	10	238	3	29276034
Pubmed	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.	WNT16 WNT7A WNT7B	3.66e-05	10	238	3	16258938
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	RND1 MAP3K9 TMEM131L MED26 DYNC1H1 SHISA2 ADAMTS5 ASXL3 EIF4A2 SRPK3 SARAF	4.39e-05	361	238	11	18976975
Pubmed	ZEB1 limits adenoviral infectability by transcriptionally repressing the coxsackie virus and adenovirus receptor.	ZEB1 CXADR	4.66e-05	2	238	2	21791114
Pubmed	Inhibition of the intrinsic factor X activating complex by protein S: evidence for a specific binding of protein S to factor VIII.	F8 PROS1	4.66e-05	2	238	2	7620160
Pubmed	MLL4 binds TET3.	KMT2B TET3	4.66e-05	2	238	2	38579707
Pubmed	Alternative promoter usage and splicing of ZNF74 multifinger gene produce protein isoforms with a different repressor activity and nuclear partitioning.	POLR2A ZNF74	4.66e-05	2	238	2	11313019
Pubmed	Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.	DCT DDT	4.66e-05	2	238	2	10079069
Pubmed	Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.	DCT DDT	4.66e-05	2	238	2	9480844
Pubmed	Associations between high factor VIII and low free protein S levels with traditional arterial thrombotic risk factors and their risk on arterial thrombosis: results from a retrospective family cohort study.	F8 PROS1	4.66e-05	2	238	2	20705334
Pubmed	ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.	ZBTB20 ATP2A2	4.66e-05	2	238	2	38166470
Pubmed	Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.	OCRL TLR9	4.66e-05	2	238	2	27398910
Pubmed	Elucidating distinct roles for NF1 in melanomagenesis.	NF1 BRAF	4.66e-05	2	238	2	23171796
Pubmed	Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.	ATP2A1 ATP2A2	4.66e-05	2	238	2	15718407
Pubmed	Distribution maps of D-dopachrome tautomerase in the mouse brain.	DDT DDTL	4.66e-05	2	238	2	23000624
Pubmed	Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.	HIGD2A HIGD2B	4.66e-05	2	238	2	32085461
Pubmed	Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress.	HIGD2A HIGD2B	4.66e-05	2	238	2	35008815
Pubmed	Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.	ATP2A1 ATP2A2	4.66e-05	2	238	2	18953100
Pubmed	FTO-mediated m 6A demethylation of ULK1 mRNA promotes autophagy and activation of hepatic stellate cells in liver fibrosis.	ULK1 FTO	4.66e-05	2	238	2	39175431
Pubmed	Clinical and genetic study of Tunisian families with genetic generalized epilepsy: contribution of CACNA1H and MAST4 genes.	MAST4 CACNA1H	4.66e-05	2	238	2	29948376
Pubmed	SERCA overexpression reduces hydroxyl radical injury in murine myocardium.	ATP2A1 ATP2A2	4.66e-05	2	238	2	16798816
Pubmed	HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.	HIGD2A HIGD2B	4.66e-05	2	238	2	37041638
Pubmed	Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.	ATP2A1 ATP2A2	4.66e-05	2	238	2	12556521
Pubmed	Direct interaction of the KRAB/Cys2-His2 zinc finger protein ZNF74 with a hyperphosphorylated form of the RNA polymerase II largest subunit.	POLR2A ZNF74	4.66e-05	2	238	2	9346935
Pubmed	RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation.	GP6 RHOG	4.66e-05	2	238	2	24106269
Pubmed	Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.	NF1 DYNC1H1	4.66e-05	2	238	2	23583712
Pubmed	Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.	ATP2A1 ATP2A2	4.66e-05	2	238	2	19644701
Pubmed	The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas.	BRAF ZEB1	4.66e-05	2	238	2	37870961
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.	ATP2A1 ATP2A2	4.66e-05	2	238	2	14638697
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	4.66e-05	2	238	2	9694715
Pubmed	Common genetic variants associated with obesity in an African-American and Hispanic/Latino population.	TUB FTO	4.66e-05	2	238	2	33983957
Pubmed	Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice.	TLR9 ATP2A2	4.66e-05	2	238	2	28490840
Pubmed	Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains.	ZBTB20 PRKN	4.66e-05	2	238	2	25678552
Pubmed	Cloning of the mouse gene for D-dopachrome tautomerase.	DDT DDTL	4.66e-05	2	238	2	9858785
Pubmed	SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.	ATP2A1 ATP2A2	4.66e-05	2	238	2	11402072
Pubmed	Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole.	DCT DDT	4.66e-05	2	238	2	8267597
Pubmed	Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance.	KLRB1 CALCR	4.66e-05	2	238	2	23226525
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	4.66e-05	2	238	2	12525170
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.	ATP2A1 ATP2A2	4.66e-05	2	238	2	10603953
Pubmed	Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.	ATP2A1 ATP2A2	4.66e-05	2	238	2	34769190
Pubmed	Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2.	TLR9 ATP2A2	4.66e-05	2	238	2	24610369
Pubmed	Modulation of Clr Ligand Expression and NKR-P1 Receptor Function during Murine Cytomegalovirus Infection.	KLRB1 CALCR	4.66e-05	2	238	2	26044139
Pubmed	WNT7A/B promote choroidal neovascularization.	WNT7A WNT7B	4.66e-05	2	238	2	29864439
Pubmed	A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.	BRAF KSR2	4.66e-05	2	238	2	21441910
Pubmed	Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage.	TCEA1 POLR2A	4.66e-05	2	238	2	12914699
Pubmed	Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.	PLXNA3 PLXNA4	4.66e-05	2	238	2	24619647
Pubmed	Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.	ATP2A1 ATP2A2	4.66e-05	2	238	2	12975374
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MON2 USP34 PFAS HNRNPL PTPN4 PTPN7 PTPRR TMEM131L VARS1 FOXK1 SDF2 WWC1 FLNB FLNC COPG1 RPAP1 FLAD1 ATP2A1 PPTC7	4.70e-05	974	238	19	28675297
Pubmed	The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis.	MYH6 ATP2A1 ATP2A2	5.01e-05	11	238	3	12122109
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	ZBTB20 MDM4 AREL1 BRAF MAP3K9 KSR2 TRIM10 ZNF74 PRKN SRPK3 MAP2K5	5.74e-05	372	238	11	22939624
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PFAS HNRNPL PHLDB1 NF1 A2ML1 POLR1B GMPPB VARS1 MED12 DYNC1H1 FLNB FLNC COPG1 POLR2A OCRL CBR1 RHOG MDC1 ACIN1 KDM2A SCRIB KIF18B ATP2A2	6.25e-05	1353	238	23	29467282
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXND1 PLXNA3 PLXNA4	6.65e-05	12	238	3	25839327
Pubmed	Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway.	MYH6 WNT7A WNT7B	6.65e-05	12	238	3	19690384
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXND1 PLXNA3 PLXNA4	6.65e-05	12	238	3	21270798
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	HDAC9 KMT2B WNT16 KDM2A TRAF3IP3	6.78e-05	62	238	5	16147992
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	PKHD1 DSCAM POLR2A ACIN1 SCRIB ATP2A1 ATP2A2 ATP2B2	8.18e-05	202	238	8	24639526
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KMT2B PFAS AREL1 MAST4 DYNC1H1 IGSF1	8.36e-05	104	238	6	9205841
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA3 RHOG PLXNA4	8.60e-05	13	238	3	11604131
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXND1 PLXNA3 PLXNA4	8.60e-05	13	238	3	10520995
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	USP34 DAG1 PLXND1 B3GAT3 NF1 OAF TMEM131L PIGO SDF2 PLXNA3 COL5A1 EDEM3 THADA CCN1 TMEM30A SARAF SCRIB NAGPA ATP2A2 CXADR PROS1	8.91e-05	1201	238	21	35696571
Pubmed	Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.	WNT16 WNT7A WNT7B POLR2A	9.48e-05	35	238	4	32907846
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SANBR KRBA1 GMPPB MAML3 HHIPL1 RAI1	9.79e-05	107	238	6	11347906
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	PTPN4 PALS1 SCRIB PDZRN3	1.06e-04	36	238	4	26053890
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	DDT HNRNPL FSIP2 TCEA1 FLNC CBR1 MDC1 ACIN1 PRKN SCRIB RPA2	1.07e-04	399	238	11	35987950
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	KDM5C HNRNPL VARS1 DYNC1H1 FLNB COPG1 POLR2A EIF4A2 MDC1 ACIN1	1.07e-04	332	238	10	32786267
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ARL14EPL ZBTB20 PLK5 HNRNPL MTUS1 A2ML1 RAD54B PLXNA3 POLR2A PARP3 ADAMTS12 HIPK3 ASXL3	1.25e-04	552	238	13	10737800
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	MYH6 WNT16 WNT7A WNT7B	1.31e-04	38	238	4	21041481
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1F ATP2A1 ATP2A2 ATP2B2	1.31e-04	38	238	4	30786075
Pubmed	SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.	ATP2A2 ATP2B2	1.39e-04	3	238	2	25661196
Pubmed	Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.	ATP2A1 ATP2A2	1.39e-04	3	238	2	27055500
Pubmed	Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.	PLXNA3 PLXNA4	1.39e-04	3	238	2	18523013
Pubmed	PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.	NF1 SUZ12	1.39e-04	3	238	2	25119042
Pubmed	Whole-genome sequencing reveals novel genes in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population.	COL9A1 COL6A6	1.39e-04	3	238	2	30577800
Pubmed	PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.	PLAGL2 ZEB1	1.39e-04	3	238	2	31827238
Pubmed	Targeting anticoagulant protein S to improve hemostasis in hemophilia.	F8 PROS1	1.39e-04	3	238	2	29317453
Pubmed	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.	DYNC1H1 DNAH12	1.39e-04	3	238	2	8666668
Pubmed	Confirmation of mutation landscape of NF1-associated malignant peripheral nerve sheath tumors.	NF1 SUZ12	1.39e-04	3	238	2	28124441
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	1.39e-04	3	238	2	12393796
Pubmed	Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 α1 subunits.	CACNA1F ATP2B2	1.39e-04	3	238	2	22183401
Interaction	DDT interactions	DDT HNRNPL DDTL PRKN RPA2	7.63e-07	16	232	5	int:DDT
GeneFamily	ATPases Ca2+ transporting	ATP2A1 ATP2A2 ATP2B2	5.00e-05	9	155	3	1209
GeneFamily	Plexins	PLXND1 PLXNA3 PLXNA4	5.00e-05	9	155	3	683
GeneFamily	PDZ domain containing	PTPN4 MAST4 LRRC7 PREX1 HTRA3 PALS1 SCRIB PDZRN3	5.03e-05	152	155	8	1220
GeneFamily	Zinc fingers CXXC-type	KMT2B TET3 KDM2A	1.28e-04	12	155	3	136
GeneFamily	Wnt family\|Endogenous ligands	WNT16 WNT7A WNT7B	5.41e-04	19	155	3	360
GeneFamily	Collagens	COL24A1 COL5A1 COL9A1 COL6A6	6.41e-04	46	155	4	490
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	BRAF KSR2	7.18e-04	5	155	2	1157
GeneFamily	Doublecortin superfamily	DCDC1 DCDC2	3.14e-03	10	155	2	1369
Coexpression	NABA_MATRISOME	PLXND1 ELFN2 COL24A1 WNT16 A2ML1 LOXL4 VWA3B PLXNA3 COL5A1 COL9A1 COL6A6 CILP PAMR1 WNT7A WNT7B MUC19 CXCL13 HTRA3 ADAMTS5 ADAMTS12 IGFBP5 CCN1 PLXNA4 CHRD ADAMTSL2 MASP2	1.58e-06	1008	236	26	MM17056
Coexpression	NABA_MATRISOME	PLXND1 ELFN2 COL24A1 WNT16 A2ML1 LOXL4 VWA3B PLXNA3 COL5A1 COL9A1 COL6A6 CILP PAMR1 WNT7A WNT7B MUC19 CXCL13 HTRA3 ADAMTS5 ADAMTS12 IGFBP5 CCN1 PLXNA4 CHRD ADAMTSL2 MASP2	2.18e-06	1026	236	26	M5889
Coexpression	PEREZ_TP53_TARGETS	MON2 ZBTB20 PLK5 PIDD1 ELFN2 TUB F8 GASK1B KRBA1 ELAPOR1 ULK1 THEMIS2 FLNC CRYBG2 RNF169 CILP WNT7A WNT7B ADAMTS5 CEMIP HIPK3 CELF2 LACC1 EHHADH KDM2A ATP2B2 CXADR SMAD5	4.26e-06	1201	236	28	M4391
Coexpression	CAIRO_HEPATOBLASTOMA_CLASSES_DN	HDAC9 HIVEP2 ZBTB20 MYLK MAST4 KLRB1 SLC27A5 ZEB1 PAMR1 KDM2A	2.51e-05	213	236	10	M12176
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYLK NDST4 CPED1 COL24A1 PHLDB1 COL5A1 ZEB1 IGFBP5 PLXNA4 PDZRN3 ADAMTSL2	4.11e-09	181	238	11	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	PHLDB1 NAV1 COL5A1 ZEB1 CILP HTRA3 ADAMTS5 IGFBP5 CHRD PDZRN3 ADAMTSL2	4.88e-09	184	238	11	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PHLDB1 OAF COL5A1 FLNB FLNC PAMR1 CXCL13 HTRA3 ADAMTS5 IGFBP5 LRRN4CL	8.47e-09	194	238	11	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	PHLDB1 OAF COL5A1 FLNC CILP HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 PDZRN3	8.93e-09	195	238	11	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 ADAMTS5 IGFBP5 CCN1 HECTD2 PLXNA4 PDZRN3 FILIP1L	1.10e-08	199	238	11	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLK5 ELFN2 AFAP1L1 PHLDB1 LRRC7 ZEB1 ADAMTS12 LRRN4CL PDZRN3 ADAMTSL2 PROS1	1.10e-08	199	238	11	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPED1 COL24A1 MTUS1 COL9A1 PAMR1 ADAMTS5 ADAMTS12 IGFBP5 PLXNA4 PDZRN3	6.39e-08	185	238	10	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL5A1 FLNC ZEB1 PAMR1 HTRA3 ADAMTS5 LRRN4CL CHRD HHIPL1 FILIP1L	7.44e-08	188	238	10	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB20 OAF NAV1 COL5A1 FLNC CALCR HTRA3 ADAMTS5 LRRN4CL CELF2	7.44e-08	188	238	10	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYLK LRRC7 TSGA10IP ZEB1 ADAMTS5 IGFBP5 PLXNA4 CXADR ADAMTSL2 FILIP1L	8.21e-08	190	238	10	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAF NAV1 COL5A1 ZEB1 CILP HTRA3 ADAMTS5 LRRN4CL CHRD ADAMTSL2	9.06e-08	192	238	10	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAF NAV1 COL5A1 ZEB1 CILP HTRA3 ADAMTS5 LRRN4CL CHRD ADAMTSL2	9.06e-08	192	238	10	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CYP26A1 COL5A1 FLNC COL6A6 PAMR1 CXCL13 ADAMTS5 IGFBP5 CELF2 PDZRN3	9.51e-08	193	238	10	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYLK CYP26A1 MAST4 COL5A1 COL6A6 PAMR1 CXCL13 ADAMTS5 ADAMTS12 PDZRN3	9.98e-08	194	238	10	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	IPF-Stromal-Fibroblast\|IPF / Disease state, Lineage and Cell class	PHLDB1 OAF COL5A1 CILP HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 PDZRN3	1.10e-07	196	238	10	f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAG1 COL5A1 PAMR1 HTRA3 ADAMTS5 IGFBP5 TMEM30A ATP2A2 PDZRN3 PROS1	1.10e-07	196	238	10	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAG1 COL5A1 PAMR1 HTRA3 ADAMTS5 IGFBP5 TMEM30A ATP2A2 PDZRN3 PROS1	1.10e-07	196	238	10	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	metastatic_Lymph_Node-Fibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MYLK COL5A1 COL6A6 CILP PAMR1 HTRA3 ADAMTS12 IGFBP5 PLPP4 PDZRN3	1.10e-07	196	238	10	275e153347caf94edc0c50021bbab49c8696fecb
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 CCN1 PLXNA4 PDZRN3 PROS1 FILIP1L	1.15e-07	197	238	10	26475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 CCN1 PLXNA4 PDZRN3 PROS1 FILIP1L	1.15e-07	197	238	10	155e63b33302a87393ace699b2f6d73abe9c5763
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 CCN1 PLXNA4 PDZRN3 PROS1 FILIP1L	1.21e-07	198	238	10	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	COPD-Stromal-Fibroblast\|COPD / Disease state, Lineage and Cell class	OAF COL5A1 CILP PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 PDZRN3	1.21e-07	198	238	10	7904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	OAF NAV1 COL5A1 CILP PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1	1.27e-07	199	238	10	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	OAF NAV1 COL5A1 CILP PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1	1.27e-07	199	238	10	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK CPED1 COL5A1 COL9A1 PAMR1 ADAMTS5 ADAMTS12 IGFBP5 PLXNA4 PDZRN3	1.27e-07	199	238	10	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 PLXNA4 PDZRN3 FILIP1L	1.33e-07	200	238	10	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 HECTD2 PLXNA4 PDZRN3	1.33e-07	200	238	10	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK CPED1 NDST3 COL9A1 PAMR1 ADAMTS5 ADAMTS12 IGFBP5 PLXNA4 PDZRN3	1.33e-07	200	238	10	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 ADAMTS5 IGFBP5 CCN1 HECTD2 PDZRN3 FILIP1L	1.33e-07	200	238	10	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 HECTD2 PLXNA4 PDZRN3	1.33e-07	200	238	10	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 ADAMTS5 IGFBP5 HECTD2 PLXNA4 PDZRN3 FILIP1L	1.33e-07	200	238	10	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK CPED1 COL9A1 PAMR1 ADAMTS5 IGFBP5 CCN1 HECTD2 PLXNA4 PDZRN3	1.33e-07	200	238	10	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 COL24A1 PKHD1 DSCAM POLR2A CXCL13 RNF17 PLXNA4 ATP2B2	3.34e-07	169	238	9	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPED1 COL24A1 COL9A1 PAMR1 ADAMTS5 ADAMTS12 IGFBP5 PLXNA4 PDZRN3	5.42e-07	179	238	9	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK CPED1 NDST3 COL24A1 COL9A1 ADAMTS5 ADAMTS12 PLXNA4 PDZRN3	6.52e-07	183	238	9	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	21-Trachea-Mesenchymal-Airway_Smooth_Muscle\|Trachea / Age, Tissue, Lineage and Cell class	MYLK CPED1 PHLDB1 ADAMTS5 CHRD HHIPL1 IGSF1 PDZRN3 ADAMTSL2	6.82e-07	184	238	9	86a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GASK1B PHLDB1 NAV1 COL5A1 ZEB1 CILP PAMR1 HTRA3 ADAMTS5	7.14e-07	185	238	9	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	PHLDB1 OAF NAV1 COL5A1 ZEB1 CILP PAMR1 IGFBP5 PDZRN3	7.14e-07	185	238	9	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 SPATA17 VWA3B CFAP47 ECT2L ARHGAP39 DNAH12 IGFBP5 CFAP74	7.14e-07	185	238	9	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPED1 COL24A1 COL9A1 PAMR1 ADAMTS5 ADAMTS12 IGFBP5 PLXNA4 PDZRN3	7.14e-07	185	238	9	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L ARHGAP39 DNAH12 CFAP74	7.14e-07	185	238	9	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MTUS1 PKHD1 MAP3K9 WWC1 DCDC2 WNT7B KSR2 RASSF7 CXADR	7.81e-07	187	238	9	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPED1 COL24A1 PHLDB1 COL5A1 ZEB1 ADAMTS5 PLXNA4 PDZRN3 ADAMTSL2	7.81e-07	187	238	9	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL24A1 OAF COL5A1 FLNC COL6A6 CILP HTRA3 ADAMTS5 ADAMTS12	8.17e-07	188	238	9	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYLK NDST4 CPED1 NDST3 LRRC7 COL9A1 ZEB1 PLXNA4 ADAMTSL2	8.17e-07	188	238	9	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK CPED1 COL24A1 PAMR1 ADAMTS5 IGFBP5 HECTD2 PLXNA4 PDZRN3	8.17e-07	188	238	9	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MON2 USP34 ZBTB20 DGKH NF1 BRAF TMEM131L DYNC1H1 CELF2	8.17e-07	188	238	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYLK LRRC7 TSGA10IP ZEB1 ADAMTS5 IGFBP5 PLXNA4 CXADR ADAMTSL2	8.17e-07	188	238	9	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPED1 COL24A1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 PLXNA4 PDZRN3	8.54e-07	189	238	9	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYLK CPED1 NDST3 OAF LRRC7 ZEB1 PLXNA4 IGSF1 ADAMTSL2	8.54e-07	189	238	9	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NDST4 CPED1 NDST3 PHLDB1 ZEB1 ADAMTS5 PLXNA4 IGSF1 ADAMTSL2	8.54e-07	189	238	9	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 CPED1 NAV1 MYO18B FLNC ZEB1 MYOM2 FILIP1L	8.92e-07	190	238	9	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	MYLK PHLDB1 COL5A1 FLNC ADAMTS5 IGFBP5 PLXNA4 PDZRN3 FILIP1L	8.92e-07	190	238	9	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	metastatic_Lymph_Node-Fibroblasts-Myofibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MYLK COL5A1 CILP HTRA3 ADAMTS12 IGFBP5 PLPP4 PDZRN3 ADAMTSL2	9.32e-07	191	238	9	aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL5A1 FLNB FLNC PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL IGSF1	9.73e-07	192	238	9	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK CYP26A1 COL24A1 COL5A1 ZEB1 ADAMTS12 IGFBP5 PLPP4 PDZRN3	9.73e-07	192	238	9	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NDST4 CPED1 NDST3 COL24A1 ZEB1 PAMR1 ADAMTS5 PLXNA4 PDZRN3	9.73e-07	192	238	9	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NDST4 CPED1 NDST3 MTUS1 ZEB1 ADAMTS5 PLXNA4 IGSF1 ADAMTSL2	1.02e-06	193	238	9	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NDST4 NDST3 KNL1 COL9A1 ZEB1 PLXNA4 IGSF1 KIF18B ADAMTSL2	1.02e-06	193	238	9	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK CYP26A1 COL24A1 COL5A1 ZEB1 ADAMTS12 IGFBP5 PLPP4 PDZRN3	1.02e-06	193	238	9	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 PIH1D2 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 CFAP74	1.06e-06	194	238	9	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 PIH1D2 SANBR SPATA17 MOK CFAP47 ECT2L DNAH12 CFAP74	1.06e-06	194	238	9	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NDST4 CPED1 NDST3 FHL5 ZEB1 ADAMTS5 PLXNA4 IGSF1 ADAMTSL2	1.06e-06	194	238	9	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYLK COL24A1 COL5A1 PAMR1 IGFBP5 CCN1 PLXNA4 PDZRN3 FILIP1L	1.06e-06	194	238	9	8fae8061b350336299aa81f378e07deadbd55123
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYLK COL24A1 COL5A1 PAMR1 IGFBP5 CCN1 PLXNA4 PDZRN3 FILIP1L	1.06e-06	194	238	9	4d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 PLXNA4 PDZRN3 PROS1 FILIP1L	1.11e-06	195	238	9	2514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DCDC1 PIH1D2 SPATA17 VWA3B MOK ECT2L DNAH12 IGFBP5 CFAP74	1.11e-06	195	238	9	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAF COL5A1 FLNC PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1	1.15e-06	196	238	9	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	MYLK CPED1 ZEB1 ADAMTS5 PLXNA4 IGSF1 PDZRN3 ADAMTSL2 FILIP1L	1.15e-06	196	238	9	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 PLXNA4 PDZRN3 PROS1 FILIP1L	1.15e-06	196	238	9	e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK COL5A1 PAMR1 IGFBP5 CELF2 PLXNA4 PDZRN3 PROS1 FILIP1L	1.15e-06	196	238	9	f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell	15-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	MYLK CPED1 ADAMTS5 IGFBP5 PLXNA4 IGSF1 PDZRN3 ADAMTSL2 FILIP1L	1.15e-06	196	238	9	0e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAF COL5A1 FLNC PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1	1.15e-06	196	238	9	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYLK COL24A1 MAST4 COL5A1 COL6A6 ADAMTS12 CELF2 HECTD2 PDZRN3	1.15e-06	196	238	9	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 IGFBP5 CFAP74	1.15e-06	196	238	9	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NDST4 SUSD3 CPED1 MTUS1 LOXL4 COL5A1 ZEB1 CXCL13 PLXNA4	1.15e-06	196	238	9	1bcae4e0a244af822e2b12b2026a2771316f107d
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 IGFBP5 CFAP74	1.15e-06	196	238	9	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAF COL5A1 FLNC PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1	1.15e-06	196	238	9	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 IGFBP5 CFAP74	1.15e-06	196	238	9	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 IGFBP5 CFAP74	1.15e-06	196	238	9	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DCDC1 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 IGFBP5 CFAP74	1.15e-06	196	238	9	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	COL5A1 CILP PAMR1 HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 PDZRN3	1.15e-06	196	238	9	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	Control-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	OAF COL5A1 CILP HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 PDZRN3	1.15e-06	196	238	9	1ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 PIH1D2 SPATA17 VWA3B MOK CFAP47 ECT2L DNAH12 CFAP74	1.20e-06	197	238	9	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK NDST4 CPED1 COL24A1 COL5A1 ZEB1 HTRA3 PDZRN3 ADAMTSL2	1.20e-06	197	238	9	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK CPED1 COL24A1 PHLDB1 COL5A1 ZEB1 PAMR1 PDZRN3 FILIP1L	1.20e-06	197	238	9	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 SANBR VWA3B MOK CFAP47 ECT2L ARHGAP39 DNAH12 CFAP74	1.20e-06	197	238	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYLK COL24A1 COL5A1 PAMR1 IGFBP5 CCN1 PLXNA4 PDZRN3 FILIP1L	1.20e-06	197	238	9	16758f181ef07c60aee63072e1da9572c5c85414
ToppCell	P07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYLK OAF PAMR1 IGFBP5 CELF2 CCN1 PDZRN3 PROS1 FILIP1L	1.20e-06	197	238	9	b1135378d768fbbe62a75747d1e8653d35252187
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK OAF ADAMTS5 CELF2 CHRD PDZRN3 ADAMTSL2 PROS1 FILIP1L	1.26e-06	198	238	9	d1e1bdd36c84e1bac21ba137f018defe98456a8c
ToppCell	18-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	MYLK COL24A1 ZEB1 ADAMTS5 PLXNA4 IGSF1 PDZRN3 ADAMTSL2 FILIP1L	1.31e-06	199	238	9	9dd130c041beaa319727f9d22b3f45ba0da49487
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 CCN1 PLXNA4	1.31e-06	199	238	9	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MYLK GASK1B COL5A1 FLNB ADAMTS5 IGFBP5 CCN1 PROS1 FILIP1L	1.31e-06	199	238	9	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	tumor_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	COL5A1 FLNB CILP HTRA3 SHISA2 ADAMTS12 IGFBP5 PLPP4 FILIP1L	1.31e-06	199	238	9	f89d67e3d8cd48ef5c30a5ad71764f4ebbc8bcb3
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MYLK GASK1B COL5A1 FLNB ADAMTS5 IGFBP5 CCN1 PROS1 FILIP1L	1.31e-06	199	238	9	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	metastatic_Brain-Fibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	MYLK OAF FHL5 COL5A1 ZEB1 PAMR1 HTRA3 ADAMTS12 CCN1	1.31e-06	199	238	9	63eb2106bb6e2e33d020628583536c8d96662c84
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLK5 ELFN2 AFAP1L1 PHLDB1 LRRC7 ZEB1 ADAMTS12 ADAMTSL2 PROS1	1.31e-06	199	238	9	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK CPED1 MTUS1 COL9A1 PAMR1 ADAMTS5 IGFBP5 PDZRN3 FILIP1L	1.37e-06	200	238	9	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 CILP HTRA3 ADAMTS5 IGFBP5 LRRN4CL CCN1 CHRD FILIP1L	1.37e-06	200	238	9	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK CPED1 COL9A1 ADAMTS5 IGFBP5 CCN1 HECTD2 PDZRN3 FILIP1L	1.37e-06	200	238	9	593bf6a7c557437db9a9249a5058a46014179ef6
Computational	Neighborhood of IKBKG	SLC22A24 TUB HNRNPL MOK POLR2A RASSF7 ZNF592 RPA2 ADAMTSL2	2.99e-05	137	125	9	MORF_IKBKG
Drug	Flufenamic acid [530-78-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	PCYT1A KMT2B PIDD1 PLXND1 CPED1 MAST4 ETAA1 PIGO OGFR WNT7A SBNO2 FLAD1	1.05e-06	198	234	12	5059_DN
Drug	colchicine; Down 200; 1uM; SKMEL5; HG-U133A	DCT PHLDB1 TINF2 FTO THEMIS2 FLNB OGFR OCRL RASSF7 THADA ACIN1	5.94e-06	195	234	11	630_DN
Drug	Retrorsine [480-54-6]; Up 200; 11.4uM; PC3; HT_HG-U133A	DCSTAMP GASK1B SPTBN5 NF1 MAST4 NR0B1 ALDH6A1 THEMIS2 ZEB1 ZNF74 SRPK3	6.23e-06	196	234	11	6601_UP
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	USP34 CYP26A1 PHLDB1 ETAA1 MAP3K9 PLXNA3 DSCAM CBR1 IGFBP5 ZNF74 NAGPA	6.23e-06	196	234	11	6775_DN
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	PCYT1A PIDD1 NF1 BRAF COL5A1 OGFR ZNF419 HIPK3 RPAP1 IGFBP5 MAP2K5	6.23e-06	196	234	11	4143_DN
Drug	clozapine; Up 200; 10uM; HL60; HT_HG-U133A	GPR37L1 DCSTAMP NDST3 MTUS1 WNT16 DNAJB5 PARP3 HIPK3 IGFBP5 SRPK3 MASP2	6.54e-06	197	234	11	2689_UP
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	USP34 PCYT1A KDM5C CYP26A1 NF1 MTUS1 POLR1B PLAGL2 DSCAM KDM2A MAP2K5	6.54e-06	197	234	11	6934_DN
Drug	Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A	KMT2B IL20RA CPED1 NF1 WNT16 FLNC CALCR CILP PARP3 IGFBP5 ATP2A2	7.20e-06	199	234	11	3353_UP
Drug	Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A	CPED1 GASK1B NF1 MTUS1 PTPRR ALDH6A1 OGFR IGFBP5 ZNF592 MAP2K5 ATP2A2	7.55e-06	200	234	11	5830_UP
Drug	Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	PLXND1 PHLDB1 NF1 MAST4 RAD54B ALDH6A1 CALCR DSCAM ADAMTS5 CEMIP	2.29e-05	185	234	10	6286_UP
Drug	Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; PC3; HT_HG-U133A	PLXND1 PHLDB1 NF1 RAD54B ETAA1 DNAJB5 KLRB1 CRYBG2 SBNO2 CCN1	3.43e-05	194	234	10	5091_UP
Drug	Mephenytoin [50-12-4]; Up 200; 18.4uM; HL60; HT_HG-U133A	ZBTB20 SPTBN5 PHLDB1 ASIC4 WWC1 DSCAM PARP3 ADAMTS12 EHHADH SRPK3	3.74e-05	196	234	10	6158_UP
Drug	Ethaverine hydrochloride [985-13-7]; Down 200; 9.2uM; PC3; HT_HG-U133A	HDAC9 PCYT1A NF1 MTUS1 PIGO WWC1 PLXNA3 PCDHA5 CCN1 ATP2A2	3.91e-05	197	234	10	6737_DN
Drug	Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A	USP34 CYP26A1 PIDD1 MDM4 NF1 WNT16 CACNA1H ALDH6A1 CALCR ERMAP	3.91e-05	197	234	10	7474_UP
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	USP34 GON4L PHLDB1 DNAJB5 PIGO PLXNA3 COL5A1 WNT7A TRIM45 MAP2K5	3.91e-05	197	234	10	5766_DN
Drug	Megestrol acetate [595-33-5]; Down 200; 10.4uM; HL60; HT_HG-U133A	DCSTAMP PHLDB1 RND1 NF1 WNT16 CRYBG2 HIPK3 ZNF74 KDM2A SMAD5	4.08e-05	198	234	10	3091_DN
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A	MON2 GON4L RND1 NF1 PTPRR ELAPOR1 CALCR DSCAM SBNO2 ZNF419	4.08e-05	198	234	10	3521_UP
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; PC3; HT_HG-U133A	KMT2B DAG1 GON4L PHLDB1 RAD54B ULK1 DNAJB5 COL5A1 SBNO2 ERMAP	4.08e-05	198	234	10	4592_DN
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	CACNA1H ZEB1 DSCAM WNT7B RASSF7 SBNO2 ZNF419 CCN1 KDM2A MAP2K5	4.26e-05	199	234	10	3574_DN
Drug	Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A	KDM5C DAG1 PLXND1 NF1 MAST4 TMEM131L ALDH6A1 IGFBP5 CCN1 SMAD5	4.26e-05	199	234	10	5302_DN
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A	HDAC9 CYP26A1 F11 PHLDB1 NF1 OGFR PARP3 RNF17 ERMAP ATP2B2	4.26e-05	199	234	10	3614_UP
Drug	Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; PC3; HT_HG-U133A	MON2 USP34 KDM5C NF1 BRAF TINF2 DNAJB5 PIGO PARP3 SBNO2	4.26e-05	199	234	10	7141_UP
Disease	Melanocytic nevus	NF1 BRAF SUZ12	1.76e-06	4	226	3	C0027962
Disease	mean arterial pressure	HDAC9 DCDC1 CYP26A1 OAF PKHD1 FTO PREX1 FHL5 COL5A1 TFAP2D EDEM3 THADA PROX2 ATP2A2	3.45e-05	499	226	14	EFO_0006340
Disease	Familial thoracic aortic aneurysm and aortic dissection	MYLK B3GAT3 MED12 COL5A1 COL9A1	5.36e-05	53	226	5	C4707243
Disease	spondylocarpotarsal synostosis syndrome (implicated_via_orthology)	MYH6 FLNB	5.84e-05	2	226	2	DOID:0090116 (implicated_via_orthology)
Disease	CXCL9 measurement	ZNF800 PRKN	5.84e-05	2	226	2	EFO_0010780
Disease	neurofibroma	NF1 SUZ12	5.84e-05	2	226	2	C0027830
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	1.74e-04	3	226	2	DOID:0080096 (implicated_via_orthology)
Disease	Brody myopathy (implicated_via_orthology)	ATP2A1 ATP2A2	1.74e-04	3	226	2	DOID:0050692 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	1.74e-04	3	226	2	DOID:0111190 (implicated_via_orthology)
Disease	Malignant Glioma	MYLK PHLDB1 NF1 BRAF SUZ12	2.04e-04	70	226	5	C0555198
Disease	mixed gliomas	MYLK PHLDB1 NF1 BRAF SUZ12	2.04e-04	70	226	5	C0259783
Disease	FEV/FEC ratio	HDAC9 USP34 HIVEP2 AFAP1L1 SPTBN5 PTPN4 SGMS1 MTUS1 WNT16 NAV1 PJA1 FTO WNT7A KSR2 ADAMTS5 THADA DNAH12 RPAP1 HHIPL1 SUZ12 PDZRN3 CXADR	2.06e-04	1228	226	22	EFO_0004713
Disease	uric acid measurement	USP34 DCDC1 SLC22A24 NAV1 FTO TSGA10IP FOXK1 SLC27A5 MOK DCDC2 DSCAM WNT7A CEMIP ATP2A2	2.82e-04	610	226	14	EFO_0004761
Disease	cystatin C measurement	HIVEP2 DCDC1 CYP26A1 SSTR4 PKHD1 FTO TFAP2D CEMIP RPAP1 PPTC7 MASP2	2.96e-04	402	226	11	EFO_0004617
Disease	anxiety	AS3MT NDST3 AREL1 DSCAM TLR9 ASXL3 PROX2 PLXNA4	3.42e-04	223	226	8	EFO_0005230
Disease	testosterone measurement	PCYT1A ZBTB20 DCDC1 AS3MT DAG1 SLC22A24 DCT NF1 NR0B1 FTO VARS1 MED12 KNL1 DSCAM POLR2A AKNA ZNF800 THADA HHIPL1 ATP2A1 ATP2B2 RAI1	3.46e-04	1275	226	22	EFO_0004908
Disease	vaginal discharge, Metrorrhagia	CPED1 WNT16	3.47e-04	4	226	2	EFO_0009365, HP_0100608
Disease	bone density, body mass index	FTO SPDYA	3.47e-04	4	226	2	EFO_0003923, EFO_0004340
Disease	platelet crit	HDAC9 ZBTB20 CYP26A1 SUSD3 DAG1 PTPN7 KRBA1 NF1 MAST4 TMEM131L POLR1B PJA1 PREX1 THEMIS2 RHOG THADA CHRD RPA2	4.21e-04	952	226	18	EFO_0007985
Disease	depressive symptom measurement	HDAC9 DAG1 AREL1 PKHD1 MAML3 MED12 KSR2 PCDHA5 CELF2 ASXL3 PROX2	4.82e-04	426	226	11	EFO_0007006
Disease	lifestyle measurement	HIVEP2 ZBTB20 DAG1 PREX1 WWC1 EDEM3 CFAP74 ATP2A1	4.84e-04	235	226	8	EFO_0010724
Disease	Sarcoma	MDM4 NF1 MAML3	5.33e-04	21	226	3	C1261473
Disease	Glioma	MYLK PHLDB1 NF1 BRAF SUZ12	5.59e-04	87	226	5	C0017638
Disease	Perineurioma	NF1 SUZ12	5.75e-04	5	226	2	C0751691
Disease	Nerve Sheath Tumors	NF1 SUZ12	5.75e-04	5	226	2	C0206727
Disease	Peripheral Nerve Sheath Neoplasm	NF1 SUZ12	5.75e-04	5	226	2	C0751689
Disease	coronary atherosclerosis measurement	HDAC9 NAV1	5.75e-04	5	226	2	EFO_0007938
Disease	Schwannomatosis, Plexiform	NF1 SUZ12	5.75e-04	5	226	2	C0751374
Disease	descending aortic diameter	HDAC9 MYH6 ZBTB20 NAV1 FLNB	5.89e-04	88	226	5	EFO_0021788
Disease	Noonan Syndrome	NF1 BRAF A2ML1	7.97e-04	24	226	3	C0028326
Disease	Neurilemmoma	NF1 SUZ12	8.58e-04	6	226	2	C0027809
Disease	foot muscle strength measurement	COL24A1 DSCAM	8.58e-04	6	226	2	EFO_0009699
Disease	response to peginterferon alfa-2a	HDAC9 SPATA17 PRKN	9.00e-04	25	226	3	EFO_0010103
Disease	unipolar depression, depressive symptom measurement	PREX1 MAML3 KSR2	1.01e-03	26	226	3	EFO_0003761, EFO_0007006
Disease	mitochondrial DNA measurement	GP6 ZBTB20 VARS1 RHOG EDEM3 THADA PRKN PDZRN3 RAI1	1.02e-03	328	226	9	EFO_0006312
Disease	colon cancer (is_marker_for)	KDM5C CHUK NF1 MTUS1	1.10e-03	59	226	4	DOID:219 (is_marker_for)
Disease	Colorectal Carcinoma	NDST3 NF1 BRAF WNT16 ETAA1 PKHD1 PIGO FLNC TLR9 RPAP1 ACIN1 KDM2A TRAF3IP3 PROS1	1.11e-03	702	226	14	C0009402
Disease	abdominal aortic artery calcification	HDAC9 NAV1	1.20e-03	7	226	2	EFO_0004859
Disease	vitamin k-dependent protein S measurement	AKNA PROS1	1.20e-03	7	226	2	EFO_0020850
Disease	1,5 anhydroglucitol measurement	PCDHA11 SI PCDHA5	1.40e-03	29	226	3	EFO_0008009
Disease	central nervous system cancer, glioma	MDM4 PHLDB1 RAVER2	1.40e-03	29	226	3	EFO_0000326, EFO_0005543
Disease	neuroimaging measurement	HDAC9 KMT2B DCDC1 PLXND1 AFAP1L1 COL24A1 PTPN4 NF1 MAST4 WNT16 PKHD1 WWC1 WNT7A KSR2 THADA KIF18B PDZRN3 RAI1	1.57e-03	1069	226	18	EFO_0004346
Disease	comparative body size at age 10, self-reported	SANBR DGKH NF1 MAST4 PKHD1 FTO CALCR KSR2 EDEM3 MAP2K5	1.58e-03	420	226	10	EFO_0009819
Disease	Moderate albuminuria, diabetic nephropathy	FTO WWC1	1.59e-03	8	226	2	EFO_0000401, HP_0012594
Disease	N2,N2-dimethylguanosine measurement	LOXL4 AGXT2	1.59e-03	8	226	2	EFO_0021125
Disease	melanoma (implicated_via_orthology)	BRAF KDM2A	1.59e-03	8	226	2	DOID:1909 (implicated_via_orthology)
Disease	Diabetes Mellitus, Non-Insulin-Dependent	BRAF FTO MOK KSR2 THADA ATP2A2 SMAD5	1.64e-03	221	226	7	C0011860
Disease	creatinine measurement	DCDC1 CYP26A1 DGKH TUB PKHD1 TMEM131L ASIC4 DCDC2 DSCAM OGFR WNT7A WNT7B SBNO2 CEMIP EDEM3 CCN1 ZNF592	1.81e-03	995	226	17	EFO_0004518
Disease	physical activity measurement, body mass index	PKHD1 FTO CALCR PRKN MAP2K5	1.88e-03	114	226	5	EFO_0004340, EFO_0008002
Disease	Dermatitis, Irritant	CBR1 TRIM10	2.03e-03	9	226	2	C0162823
Disease	Colon Carcinoma	BRAF RAD54B	2.03e-03	9	226	2	C0699790
Disease	age at menarche	USP34 ZBTB20 NDST4 DAG1 SPATA17 FTO SLC27A5 TFAP2D DSCAM AGXT2 IGSF1 MAP2K5	2.23e-03	594	226	12	EFO_0004703
Disease	chronic kidney disease	DCDC1 NDST3 ZAR1L FTO TET3 DSCAM PDZRN3	2.32e-03	235	226	7	EFO_0003884
Disease	migraine disorder, endometriosis	FHL5 POLR2A KIF18B MAP2K5	2.41e-03	73	226	4	EFO_0001065, MONDO_0005277
Disease	Intellectual Disability	HIVEP2 KDM5C GON4L NF1 PJA1 TET3 DYNC1H1 ACIN1 SUZ12 RAI1	2.49e-03	447	226	10	C3714756
Disease	smoking behavior, body mass index	NAV1 FTO CALCR PRKN MAP2K5	2.62e-03	123	226	5	EFO_0004318, EFO_0004340
Disease	Growth Disorders	TINF2 RAI1 ADAMTSL2	2.63e-03	36	226	3	C0018273
Disease	intellectual disability (implicated_via_orthology)	HIVEP2 KDM5C NDST4 NDST3	2.66e-03	75	226	4	DOID:1059 (implicated_via_orthology)
Disease	wellbeing measurement	HIVEP2 DAG1 AREL1 SGMS1 PTPRR PKHD1 PREX1 MAML3 DCDC2 DSCAM MUC19 CELF2 ASXL3	2.78e-03	692	226	13	EFO_0007869
Disease	cardiovascular disease	USP34 HIVEP2 DCDC1 SPTBN5 PKHD1 NAV1 FTO PREX1 TFAP2D THADA	2.91e-03	457	226	10	EFO_0000319
Disease	nucleus accumbens volume change measurement	WWC1 DSCAM	3.07e-03	11	226	2	EFO_0021493
Disease	sleep disorder (implicated_via_orthology)	NF1 TFAP2D	3.07e-03	11	226	2	DOID:535 (implicated_via_orthology)
Disease	urate measurement, bone density	DDX59 FSIP2 SPATA17 MAST4 A2ML1 NAV1 VWA3B FTO COL5A1 DSCAM PLXNA4 ATP2B2	3.12e-03	619	226	12	EFO_0003923, EFO_0004531
Disease	melanoma	NF1 BRAF MAP3K9 FTO KLRB1 SUZ12 RAI1	3.13e-03	248	226	7	C0025202
Disease	Glioblastoma	MDM4 NF1 PRKN SUZ12	3.21e-03	79	226	4	C0017636
Disease	aortic measurement	HDAC9 DCDC1 PTPRR NAV1 PREX1 FLNB CXADR	3.34e-03	251	226	7	EFO_0020865
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH6 DAG1 MDM4 FLNC	3.36e-03	80	226	4	DOID:12930 (implicated_via_orthology)
Disease	cognitive function measurement	USP34 SGSM1 CYP26A1 SSTR4 MAST4 PKHD1 LOXL4 VWA3B CACNA1H LRRC7 MYO18B PREX1 MAML3 COL5A1 TFAP2D DSCAM POLR2A CEMIP EDEM3 CELF2 PLXNA4	3.52e-03	1434	226	21	EFO_0008354
Disease	Drugs used in diabetes use measurement	HIVEP2 NF1 PTPRR FTO KSR2 THADA RPAP1	3.64e-03	255	226	7	EFO_0009924
Disease	Mitral valve prolapse, response to surgery	AREL1 ZNF592	3.66e-03	12	226	2	EFO_0009951, HP_0001634
Disease	triacylglycerol 44:1 measurement	DSCAM PRKN	3.66e-03	12	226	2	EFO_0010399
Disease	longitudinal BMI measurement	FTO CALCR WNT7B KSR2	3.68e-03	82	226	4	EFO_0005937
Disease	cortical surface area measurement	MON2 HDAC9 USP34 DCDC1 PLXND1 CPED1 AFAP1L1 COL24A1 MAST4 PKHD1 NAV1 WWC1 FLNB WNT7A ARHGAP39 THADA CELF2 MDC1 PDZRN3 SMAD5	3.69e-03	1345	226	20	EFO_0010736
Disease	urate measurement	USP34 ZBTB20 DCDC1 GON4L SPATA17 OAF PKHD1 NAV1 MYO18B FTO TSGA10IP VARS1 FOXK1 MOK CEMIP	3.97e-03	895	226	15	EFO_0004531
Disease	Giant Cell Glioblastoma	MDM4 NF1 PRKN SUZ12	4.01e-03	84	226	4	C0334588
Disease	velocity of sound measurement	CPED1 WNT16	4.31e-03	13	226	2	EFO_0005654
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP2 SMAD5	4.31e-03	13	226	2	DOID:0050787 (implicated_via_orthology)
Disease	xanthine measurement	KSR2 CELF2	4.31e-03	13	226	2	EFO_0010548
Disease	Profound Mental Retardation	KDM5C GON4L NF1 DYNC1H1 RAI1	4.42e-03	139	226	5	C0020796
Disease	Mental Retardation, Psychosocial	KDM5C GON4L NF1 DYNC1H1 RAI1	4.42e-03	139	226	5	C0025363
Disease	Mental deficiency	KDM5C GON4L NF1 DYNC1H1 RAI1	4.42e-03	139	226	5	C0917816
Disease	neuroticism measurement, cognitive function measurement	NAV1 FTO DSCAM PCDHA11 PCDHA5 CELF2 HECTD2 ASXL3 PRKN NAGPA RAI1	4.49e-03	566	226	11	EFO_0007660, EFO_0008354
Disease	physical activity	HDAC9 PKHD1 LRRC7 CRYBG2	4.73e-03	88	226	4	EFO_0003940
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	DAG1 GMPPB	5.00e-03	14	226	2	C1836373
Disease	alpha-Dystroglycanopathies	DAG1 GMPPB	5.00e-03	14	226	2	C2936406
Disease	Neoplasm of lung	BRAF PRKN	5.00e-03	14	226	2	cv:C0024121
Disease	Fukuyama Type Congenital Muscular Dystrophy	DAG1 GMPPB	5.00e-03	14	226	2	C0410174
Disease	chromosome-type aberration frequency	FTO SUZ12	5.00e-03	14	226	2	EFO_0009861
Disease	Lung cancer	BRAF PRKN	5.00e-03	14	226	2	cv:C0242379
Disease	LUNG CANCER	BRAF PRKN	5.00e-03	14	226	2	211980
Disease	Muscle eye brain disease	DAG1 GMPPB	5.00e-03	14	226	2	C0457133
Disease	Sarcoma, Spindle Cell	NF1 MAML3	5.00e-03	14	226	2	C0205945
Disease	Sarcoma, Epithelioid	NF1 MAML3	5.00e-03	14	226	2	C0205944
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	DAG1 GMPPB	5.00e-03	14	226	2	C4284790
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	DAG1 FTO PRKN ATP2A1 ATP2A2	5.59e-03	147	226	5	DOID:9352 (biomarker_via_orthology)
Disease	cortical thickness	MON2 HDAC9 KMT2B DCDC1 AS3MT PLXND1 CPED1 AFAP1L1 PHLDB1 MAST4 WNT16 PKHD1 NAV1 FLNB WNT7A THADA PROX2	5.60e-03	1113	226	17	EFO_0004840
Disease	Walker-Warburg congenital muscular dystrophy	DAG1 GMPPB	5.74e-03	15	226	2	C0265221
Disease	Body Weight	FTO MAP2K5	5.74e-03	15	226	2	C0005910
Disease	RASopathy	NF1 BRAF	5.74e-03	15	226	2	cv:C5555857
Disease	osteoarthritis (implicated_via_orthology)	COL9A1 ADAMTS5	5.74e-03	15	226	2	DOID:8398 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRLQPERGSPKKCEA	ACIN1	721	Q9UKV3
KISCRPLPREEVNQI	AGXT2	446	Q9BYV1
ERQLKCLAFRNPGPQ	ARL14EPL	36	P0DKL9
LPNKQRTVVPARCGV	BRAF	161	P15056
PKDLEPRAANCTRVL	B3GAT3	291	O94766
VLRDRSQNPPQSKGC	CELF2	71	O95319
PCNDVIKPGTVKRLR	DNAJB5	291	O75953
DPEVLTRNSACKPRG	LINC01590	46	Q5TEZ4
ANRLPEIQQPLCRKE	CPED1	181	A4D0V7
KKELRQANCPSLRPQ	ADAMTSL4-AS1	71	Q5T5F5
VPNGELVRRDPVSCK	CALCR	206	P30988
NRKLAKGCPLSQRPS	ADAMTS5	906	Q9UNA0
AECKRQGLPITPRNK	BTBD6	311	Q96KE9
VKETRICEVRPCGQP	CCN1	261	O00622
VEIGKARCEQPTSPR	A2ML1	1331	A8K2U0
SVLKPRCQPRLSQTV	ECT2L	216	Q008S8
LPTKLTPNTCVQRRV	DNHD1	4731	Q96M86
PGKICNRPIDIQATT	CEMIP	351	Q8WUJ3
PANRVPAGLEKRLCA	DDTL	11	A6NHG4
DPPRKEVTGSIQLCR	ATP2A1	601	O14983
PEVPEAIRKCQRAGI	ATP2B2	711	Q01814
APAAINRSIPCKVIV	ASXL3	1461	Q9C0F0
RRQKVPETKEPTCGL	ADAMTS12	196	P58397
IAEVKRRLSPPECLN	TFAP2D	231	Q7Z6R9
APSELRALQKRCLVP	NDST3	731	O95803
KERQLLPQECPVGAQ	RASSF7	56	Q02833
PKIENVVFCRPGALQ	RAD54B	541	Q9Y620
ADPLCRNPTNRSLKG	RAI1	1396	Q7Z5J4
LLQPQLCGRAVKPAV	RAVER2	356	Q9HCJ3
TRGCGRVVKLQQLPE	PDZRN3	86	Q9UPQ7
PSPCLLRDQRLGVKS	ARHGAP39	431	Q9C0H5
KVAQAQPVDPTCRVL	AFMID	226	Q63HM1
KQDILTGRLPCPSNT	PTPN4	131	P29074
KTILPNPQSRVCLGR	PTPN7	126	P35236
GPVRTVTKRVQPCSL	PARP3	171	Q9Y6F1
VLRRRLATPNTCPNK	PPP2R3C	6	Q969Q6
PAGRKPSFTIQCLQR	CACNA1F	1796	O60840
GPLITPQAKERVCNL	ALDH6A1	356	Q02252
QQRRQRVCSEEGPPK	PCDHA11	751	Q9Y5I1
PGRKTQCTEILNLPS	DCDC1	961	M0R2J8
TRPKPKILRGQGESC	KRBA1	881	A5PL33
CQVQVAPARGKLRPA	LOXL4	261	Q96JB6
ILPPRNLCIKEGATA	MYLK	36	Q15746
LQVPCKELQRVGPAA	LRRN4CL	56	Q8ND94
TQPSCIKRQRAAGNP	MDC1	1716	Q14676
NGRLPEIKLPVNGCS	MAML3	246	Q96JK9
FLCPQKELTRGVRPT	IFNLR1	291	Q8IU57
ACRISPGQINQVRPK	MDM4	16	O15151
KIIDASRRAPPGKCQ	HHIPL1	571	Q96JK4
RLRGQSCKEPPEVQS	WWC1	1076	Q8IX03
EKSRQKNPRSLCIQP	MTUS1	876	Q9ULD2
ATRGPQPGRCLIQTK	LRRC7	1421	Q96NW7
RSCQRKGVPIQTPRE	HHLA3	86	Q9XRX5
CQSRIARTLPADQKP	FTO	456	Q9C0B1
QRGGPVDLTLKQPRC	CHUK	286	O15111
RTESVPCDINNPLRK	KSR2	471	Q6VAB6
IRVRCSPQKTVPGSL	ELAPOR1	816	Q6UXG2
REPLKNVVDKSCPRG	EDEM3	546	Q9BZQ6
LRQKQPERLCSGPGI	GMPPB	236	Q9Y5P6
REPPPICLDVRQKQR	HECTD2	91	Q5U5R9
LEPCPKEQIAGLSRR	DAG1	666	Q14118
NPVRIITGEKNLPCA	DDX59	401	Q5T1V6
SVPLCNKINRQASPR	FSIP2	3641	Q5CZC0
QPLESRRLCNKPIQS	EHHADH	191	Q08426
SLVPLEKPVTLRCQG	GP6	36	Q9HCN6
SGRDEPCLLKRLPNN	FLNB	1946	O75369
PSKVQRCAVGLRQPA	PCYT1A	31	P49585
KNRASPPRQTILCLF	PLXNA3	326	P51805
QEGRVKLPEDCPQLL	PLXNA4	691	Q9HCM2
TGPACERKLNIQLQP	PLXND1	426	Q9Y4D7
GQLIEPLQIFPRACK	MAP2K5	96	Q13163
RNIPVFDENLPCKRG	MUC19	1201	Q7Z5P9
CRGNILIPGLSQKPI	KIF22	201	Q14807
PPLGSNKKVQRCSVL	CSNKA2IP	56	A0A1B0GTH6
QQRPCVLPLNKEERR	DCSTAMP	261	Q9H295
PANRVPAGLEKRLCA	DDT	11	P30046
IRAPSGNEEPCLLKR	FLNC	1981	Q14315
LRCLRPDKITPAITN	DNAH12	2451	Q6ZR08
RKVGQRLLTQCRPPC	PLK5	96	Q496M5
SPNPCIDIRKATRIL	LACC1	366	Q8IV20
DPLVKPVGRQACDLQ	ADAMTSL2	891	Q86TH1
PRLPNKRNCSVTGID	KNL1	1681	Q8NG31
RTNDLKILPGQAVCP	L3MBTL4	366	Q8NA19
LRCNTLPDTGRRKPQ	MED12	81	Q93074
QGLRCLPRQDEEKPL	IGFBP5	76	P24593
AKQGRTERLCSQNPP	F8	1646	P00451
RPAGPCRRKQQAVVV	KMT2B	226	Q9UMN6
LKPAPQQCRLPTIVR	MOK	401	Q9UQ07
LQELKEQSPCPSRGR	ASIC4	496	Q96FT7
ERLSGKCPLPRQQVT	MON2	1626	Q7Z3U7
PSDLKTLQRRCLVPG	NDST4	731	Q9H3R1
QQRRQRVCSGEAPPK	PCDHA5	751	Q9Y5H7
NLPVLNTRIICPGLR	DGKH	711	Q86XP1
LNKANPRCPESLTRD	DGKH	1031	Q86XP1
SICQPLIKGRSAPGR	HIPK3	1016	Q9H422
LSPLCPSNRRNGKDL	KIF18B	821	Q86Y91
PCLQPKASVLQQLDR	MED26	241	O95402
VCTNTIKLIVGRPRP	PLPP4	96	Q5VZY2
IQILPRGNGCPRKEI	CXCL13	51	O43927
RKTRENPVVPIGCLA	HIGD2A	41	Q9BW72
PRRAQPSEKQCARTL	IL20RA	226	Q9UHF4
VRQREQPPTAALCSK	ETAA1	56	Q9NY74
PNPLSRVCLRPKNVT	PTPRR	426	Q15256
GALRPVALKSPQVVC	NR0B1	241	P51843
ANRKRPIILIGPQNC	PALS1	476	Q8N3R9
NAQAGVSPRCPKKAR	PROX2	86	Q3B8N5
CERLVKEGRFVPSNP	PPTC7	101	Q8NI37
SRKAEFIQDGRPCPI	GASK1B	296	Q6UWH4
PPRIEVASSVKLCRQ	ATP2A2	601	P16615
ENCRQPIGTKPLISK	FHL5	131	Q5TD97
TPVRQLQKGACPLGL	HTRA3	116	P83110
RKTRENPVVPIGFLC	HIGD2B	41	Q4VC39
SPTIRGQELQLRCKG	IGSF1	691	Q8N6C5
KQSCVLRQCLAPRLP	KDM2A	601	Q9Y2K7
IPNCGTPKQRITILQ	FILIP1L	936	Q4L180
LPKVRPIERCQSILA	GPR37L1	236	O60883
DQCLLRLNVVPPSNK	CXADR	221	P78310
LRKVPGQLPLLCSER	CRYBG2	941	Q8N1P7
RNQVGPEVRSCPKAS	GON4L	1996	Q3T8J9
CPKASPRLQKEREGQ	GON4L	2006	Q3T8J9
QRPICLPSKGDRNVI	F11	496	P03951
RRGAPALQLPKQCTF	FOXK1	176	P85037
GKAEATRVLPRQCPV	AKNA	806	Q7Z591
TRVLPRQCPVQAEKS	AKNA	811	Q7Z591
GIQPPVELSCKERNI	AREL1	406	O15033
QKIGFCPPRLVTANL	AS3MT	221	Q9HBK9
KRPLGTQQNPARTCK	COL5A1	1626	P20908
RRNEDKPIAPCGAIA	TMEM30A	161	Q9NV96
VCTELLPLIKPQGRV	CBR1	121	P16152
PSAIQQRAIIPCIKG	EIF4A2	56	Q14240
KVVINSNITPICLPR	MASP2	541	O00187
RARPVEQGCLKRPVS	MAST4	1501	O15021
APQRQRPCRKKGVSI	ANKS3	251	Q6ZW76
NPCGPVQRIVIFRKN	HNRNPL	216	P14866
VKLERIQFVGACNPP	DYNC1H1	2701	Q14204
NELCPKIRIGQDDLP	COL9A1	41	P20849
VDCNRIESLPIKPRG	COL9A1	196	P20849
IGCVIKETLRLNPPV	CYP26A1	356	O43174
ARVFNETPINPRKCA	COPG1	31	Q9Y678
QKCETQTLRQGVPLP	HDAC9	351	Q9UKV0
ENTVRNPALKCLSPG	FLAD1	551	Q8NFF5
PTKCRDRDGQVVALP	CACNA1H	1211	O95180
CRDIIAKSQGSRDPP	C4orf54	346	D6RIA3
KSPPVVIQCQSRKRA	CFAP47	2896	Q6ZTR5
ELQVGCIRTTQPSPK	CFAP74	1536	Q9C0B2
NVSARFRKPLQEPCT	DCDC2	126	Q9UHG0
PNIIALRGVCLKEPN	MAP3K9	201	P80192
KCNRLNSIDPKQPPR	COL6A6	2181	A6NMZ7
DPEQVLLQCLPRNKV	PIDD1	626	Q9HB75
KRVCGNERPAPIQSI	PAMR1	196	Q6UXH9
KVQPRAQDEARSPCL	PCARE	421	A6NGG8
QPCRQPLGARVADKV	OGFR	441	Q9NZT2
PPCRRGVNNISVSLK	NAV1	1506	Q8NEY1
QACLEPQKSRTLKRP	DSCAM	1926	O60469
QTSFRLKEPPRCVGI	ERMAP	346	Q96PL5
PLCNRSKDVVEPLLR	VARS1	661	P26640
RQLQRDLDCGPQKLP	TSGA10IP	326	Q3SY00
FPRSEILPPINRKQC	SPATA17	226	Q96L03
SKRPKGPCLVIQRQD	SPDYA	56	Q5MJ70
GNRTGTCAKLRLPPQ	SUSD3	26	Q96L08
LKPRSLQSQIGILCP	TRIM45	81	Q9H8W5
EVLNRCPNVSLQKLP	THADA	1121	Q6YHU6
GRRQPCKEVSAAPAI	PRSS58	186	Q8IYP2
KGPCQRVQPGKLRVQ	PRKN	151	O60260
RGKNCLPVNTPQSRI	TMEM131L	946	A2VDJ0
SIPLDSNLRPQKCQR	SLC22A24	76	Q8N4F4
RRLDPIPQLKCVGGT	SARAF	56	Q96BY9
VLNPTPIKRGRSCIL	RHOG	176	P84095
APQPVVARCKLVLVG	RND1	6	Q92730
VKQCLQPPEATLRAG	NAGPA	426	Q9UK23
KIPDQPDTLCFQIRG	PREX1	711	Q8TCU6
CQQEALQPEPGRKRI	SSTR4	366	P31391
RCLRPKQDPQQSRAP	SHISA2	141	Q6UWI4
ADVKRRQAPALGCPA	SBNO2	1226	Q9Y2G9
LRKNVLCGNIPPDLF	TCEA1	206	P23193
CKVPPRGKDGRIVNV	PKHD1	1071	P08F94
GKCPNVLNDPVNVRI	SI	61	P14410
EPLVLKTNLERCPAR	RNF169	231	Q8NCN4
GRPPLAQIQKVNICL	SAPCD1	96	Q5SSQ6
PGLRELCIQKAPGER	SCRIB	1096	Q14160
HQRGCREKIDPLVPQ	TEX45	481	Q8NA69
FVRCIIPNERKAPGV	MYH6	671	P13533
RIPCIPGKINVDRRG	SANBR	341	Q6NSI8
SELIKPINPRLDGCI	PROS1	436	P07225
ALPKASEQAELPRCR	OAF	191	Q86UD1
KGPLREPCALTLAQR	OCRL	21	Q01968
VPRPRGREAESQVKC	PLAGL2	26	Q9UPG8
ERGTPIKCGQPIRLT	SDF2	81	Q99470
RQEKTRLIGPNCPGV	SUCLG1	161	P53597
LETAGRVQKLCPGPQ	SPTBN5	1896	Q9NRC6
QPSKCVTIPRSLDGR	SMAD5	61	Q99717
QGLPVPCVKSIVRQV	SRPK3	181	Q9UPE1
QPLPVNCVSELRKRS	AFAP1L1	731	Q8TED9
KVIPQGSCRRASVNP	CILP	1026	O75339
EKVQCPRLACAQPVR	CHRD	826	Q9H2X0
IKNPLGTRDNPARIC	COL24A1	1531	Q17RW2
TELIPIEGRNTRKPC	RNF17	486	Q9BXT8
LNAKRNKTPVQDCPR	PRAMEF6	126	Q5VXH4
AAPEPQLCLQTRILK	PIH1D2	46	Q8WWB5
RRPGQVTVLKEPLSC	TRAF3IP3	91	Q9Y228
IICNKIPGLAPRQRA	WNT7B	36	P56706
QVLNLIKACPRPEGL	RPA2	211	P15927
GLKIRGCLSRQPPDT	SLC27A5	101	Q9Y2P5
KNPCRQALEVAPGAL	TLR9	181	Q9NR96
SAQCPQFGIPRKRLK	SPOPL	376	Q6IQ16
PCQTLGGRALKENPV	TINF2	331	Q9BSI4
RKDVSCPIRQVPTGK	SUZ12	196	Q15022
NRVIRACVEAPKGNP	PFAS	496	O15067
PTGDSKVVLPCNLLR	POLR2A	971	P24928
ELGTCSSVPPRQRLK	ZNF592	261	Q92610
FQPGRPLRVVATKDC	THEMIS2	341	Q5TEJ8
APCIRLKQPRSGLLQ	SERINC4	276	A6NH21
TPPICRQAQTKLEVA	NF1	676	P21359
KPPLCRVSSDNGQRL	SGMS1	46	Q86VZ5
VPEKLGCANLPLNSR	WNT16	41	Q9UBV4
VRQDSPTKRPALCIQ	SGSM1	211	Q2NKQ1
PCVQRKLSSGDLRVP	PHLDB1	556	Q86UU1
GLQPLVEPCLRQTLK	RPAP1	766	Q9BWH6
RLPEPAKSCRQRQLE	TET3	1151	O43151
PNCERKKPPVIRQNI	DCT	116	P40126
INCSKARPGQLLPLR	ZCCHC13	141	Q8WW36
QKIISSLDPPCRRGA	UNC5A	761	Q6ZN44
QARAKLPPVCRAVAG	MYO18B	1131	Q8IUG5
VRLKQRLLERPCQEP	nan	116	Q3C1V9
CRKQPRPVRIQTLVG	ZBTB20	311	Q9HC78
KCISLIPVNGRPRTG	ZEB1	291	P37275
CRKPVAVSPELGQRI	TRIM10	266	Q9UDY6
IICNKIPGLAPRQRA	WNT7A	36	O00755
VAKLLCVVPPRAGRN	ZNF74	621	Q16587
GRSKNVLVPLSRSCP	ZNF800	276	Q2TB10
PFLCESQGLRKRQQP	PIGO	961	Q8TEQ8
IPRPTCIGDRQENDK	ZNF18	281	P17022
KQSLPLRVVCQPAGL	USP34	1206	Q70CQ2
RPDPLKGQKVIARCD	VWA3B	1031	Q502W6
PCRLVRPVQNLALGK	POLR1B	616	Q9H9Y6
DLSRPQKPQLVRQGC	HIVEP2	1486	P31629
PLKRQEGRVPVLRSC	ZNF419	136	Q96HQ0
TPRTKEEDCRLNGPQ	ZNF425	106	Q6IV72
VRPKIRNLASPNCVK	PJA1	256	Q8NG27
LRPAPQGITIKCRIT	TUB	256	P50607
LQSCRNLRGSPKLPD	ULK1	596	O75385
SPRVDKAVQCSLGPR	ZAR1L	96	A6NP61
LQAKCRNGSLPARPV	ELFN2	241	Q5R3F8
SRNKTTERPGLLNCP	KLRB1	81	Q12918
QRLPVRLPEGEALQC	KDM5C	1266	P41229
SPLKVLCTPEGIRLQ	MYOM2	1236	P54296