Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH1 MYH2 TRAF3IP1 CD2AP CEP57L1 EPB41L3 OPA1 KIF7 CCDC88A DST EML5 BAIAP2L1 FMN1 SYN1 ROCK1 TRAK2 DMD GOLGA8A KLC1

1.91e-06109910019GO:0008092
GeneOntologyMolecularFunctionmicrotubule binding

TRAF3IP1 CEP57L1 OPA1 KIF7 CCDC88A DST EML5 FMN1 GOLGA8A

2.45e-053081009GO:0008017
GeneOntologyMolecularFunctionmedium-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

2.48e-0521002GO:0140981
GeneOntologyMolecularFunction16-hydroxypalmitate dehydrogenase activity

CYP4A11 CYP4A22

2.48e-0521002GO:0103002
GeneOntologyMolecularFunctiontubulin binding

TRAF3IP1 CEP57L1 OPA1 KIF7 CCDC88A DST EML5 FMN1 GOLGA8A KLC1

5.72e-0542810010GO:0015631
GeneOntologyMolecularFunctionactin binding

MYH1 MYH2 CD2AP EPB41L3 CCDC88A DST BAIAP2L1 FMN1 SYN1 DMD

1.45e-0447910010GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein-membrane anchor activity

EPB41L3 SYN1

1.48e-0441002GO:0106006
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4A11 CYP4A22

5.13e-0471002GO:0050051
GeneOntologyMolecularFunctioninositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

INPP5B OCRL

5.13e-0471002GO:0052659
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4A11 CYP4A22

5.13e-0471002GO:0018685
GeneOntologyMolecularFunctionRNA helicase activity

DDX49 DDX6 DDX46 DDX21

6.36e-04781004GO:0003724
GeneOntologyMolecularFunctioninositol-polyphosphate 5-phosphatase activity

INPP5B OCRL

6.82e-0481002GO:0004445
GeneOntologyMolecularFunctioninositol-1,4,5-trisphosphate 5-phosphatase activity

INPP5B OCRL

6.82e-0481002GO:0052658
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX49 DDX6 DDX46 DDX21

7.00e-04801004GO:0008186
GeneOntologyMolecularFunctionSH3 domain binding

ENKUR CD2AP SH3GL1 AFAP1L2 FMN1

7.66e-041431005GO:0017124
GeneOntologyMolecularFunctioninositol tetrakisphosphate phosphatase activity

INPP5B OCRL

8.74e-0491002GO:0052743
GeneOntologyMolecularFunctioncalmodulin binding

MYH1 MYH2 ENKUR ATP5IF1 PPP3CC PCNT

1.06e-032301006GO:0005516
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4A11 CYP4A22

1.09e-03101002GO:0052869
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

INPP5B OCRL

1.09e-03101002GO:0004439
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

1.09e-03101002GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

1.09e-03101002GO:0102033
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

ATG16L1 EPB41L3 SYN1

1.48e-03451003GO:0043495
GeneOntologyMolecularFunctionenzyme inhibitor activity

ATP5IF1 RPS7 DTX3L ITIH5 PPP1R8 ROCK1 DDX21 PPP1R16A

1.54e-034351008GO:0004857
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate phosphatase activity

INPP5B OCRL

1.59e-03121002GO:0106019
GeneOntologyMolecularFunctionNAD(P)H oxidase H2O2-forming activity

AIFM1 CYB5R4

1.59e-03121002GO:0016174
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DDX49 SEPTIN4 OPA1 SEPTIN6 DDX6 KIF7 DDX46 ABCA6 MTIF2 SHOC1 DDX21

1.72e-0377510011GO:0017111
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

INPP5B OCRL

1.87e-03131002GO:0034595
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4A11 CYP4A22

1.87e-03131002GO:0016713
GeneOntologyMolecularFunctioninositol trisphosphate phosphatase activity

INPP5B OCRL

2.17e-03141002GO:0046030
GeneOntologyMolecularFunctionarachidonate binding

CYP4A11 CYP4A22

2.50e-03151002GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4A11 CYP4A22

2.85e-03161002GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4A11 CYP4A22

2.85e-03161002GO:0050543
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYH2 KIF7 KLC1

2.94e-031181004GO:0003774
GeneOntologyMolecularFunctionprotein kinase activity

TLK2 MAP3K5 JAK1 TLK1 RNASEL PKM ROCK1 PRKCQ MAPK11

3.16e-036001009GO:0004672
GeneOntologyMolecularFunctionpyrophosphatase activity

DDX49 SEPTIN4 OPA1 SEPTIN6 DDX6 KIF7 DDX46 ABCA6 MTIF2 SHOC1 DDX21

3.17e-0383910011GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DDX49 SEPTIN4 OPA1 SEPTIN6 DDX6 KIF7 DDX46 ABCA6 MTIF2 SHOC1 DDX21

3.20e-0384010011GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DDX49 SEPTIN4 OPA1 SEPTIN6 DDX6 KIF7 DDX46 ABCA6 MTIF2 SHOC1 DDX21

3.20e-0384010011GO:0016818
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor binding

CD2AP CCDC88A

3.22e-03171002GO:0005172
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 MYH2 DDX49 DDX6 KIF7 DDX46 ABCA6 SHOC1 DDX21

3.68e-036141009GO:0140657
GeneOntologyMolecularFunctionprotein domain specific binding

ENKUR CD2AP SH3GL1 DDX6 MAP3K5 CCDC88A AFAP1L2 FMN1 TRAK2 DMD DNAJA1

4.36e-0387510011GO:0019904
GeneOntologyMolecularFunctioninositol phosphate phosphatase activity

INPP5B OCRL

4.45e-03201002GO:0052745
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

AIFM1 CYB5R4

4.45e-03201002GO:0050664
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

TRIT1 DDX49 DDX6 PPP1R8 DDX46 RNASEL DDX21

4.99e-034171007GO:0140098
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4A11 CYP4A22

6.38e-03241002GO:0008392
GeneOntologyMolecularFunctioncytoskeletal anchor activity

EPB41L3 SYN1

6.38e-03241002GO:0008093
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX49 DDX6 KIF7 DDX46 ABCA6 SHOC1 DDX21

6.73e-034411007GO:0016887
GeneOntologyMolecularFunctionmRNA 5'-UTR binding

RPS7 UTP23

6.91e-03251002GO:0048027
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TLK2 MAP3K5 TLK1 PKM ROCK1 PRKCQ MAPK11

7.14e-034461007GO:0004674
GeneOntologyMolecularFunctioncadherin binding

CD2AP TRPC4 SH3GL1 DDX6 BAIAP2L1 PKM

7.19e-033391006GO:0045296
GeneOntologyMolecularFunctionrRNA binding

UTP23 RNASEL DDX21

7.32e-03791003GO:0019843
GeneOntologyBiologicalProcessmicrotubule-based process

CCNL2 ATG16L1 ENKUR TRAF3IP1 SEPTIN4 INPP5B NCKAP5 OPA1 KIF7 CCDC88A DST ROCK1 TRAK2 PARD3 DNAJA1 GOLGA8A ODAD3 KLC1 PCNT

4.09e-0710589719GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

ATG16L1 ENKUR TRAF3IP1 SEPTIN4 INPP5B OPA1 KIF7 DST TRAK2 DNAJA1 ODAD3 KLC1

3.44e-064939712GO:0007018
GeneOntologyBiologicalProcesslauric acid metabolic process

CYP4A11 CYP4A22

6.55e-053972GO:0048252
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

ATG16L1 TRAF3IP1 OPA1 CCDC88A DST TRAK2 KLC1

9.36e-05225977GO:0030705
GeneOntologyBiologicalProcessaxo-dendritic transport

ATG16L1 OPA1 DST TRAK2 KLC1

9.97e-0598975GO:0008088
GeneOntologyBiologicalProcessregulation of establishment of protein localization to mitochondrion

ATP5IF1 LMAN1 DNAJA1 FBXW7

1.13e-0453974GO:1903747
GeneOntologyCellularComponentsperm annulus

SEPTIN4 SEPTIN6 DDX6

8.48e-069993GO:0097227
GeneOntologyCellularComponentsupramolecular fiber

TLK2 MYH1 MYH2 ENKUR CD2AP CEP57L1 NCKAP5 OPA1 DDX6 KIF7 DST LMAN1 EML5 FMN1 DMD GOLGA8A KLC1 PCNT

9.49e-0611799918GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TLK2 MYH1 MYH2 ENKUR CD2AP CEP57L1 NCKAP5 OPA1 DDX6 KIF7 DST LMAN1 EML5 FMN1 DMD GOLGA8A KLC1 PCNT

1.04e-0511879918GO:0099081
GeneOntologyCellularComponentcilium

ATG16L1 ENKUR TRAF3IP1 SEPTIN4 OCRL SEPTIN6 DDX6 KIF7 CCDC88A PPP3CC PKM AGBL2 ODAD3 KLC1 PCNT

2.06e-058989915GO:0005929
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

TLK2 ENKUR CD2AP CEP57L1 NCKAP5 OPA1 DDX6 KIF7 DST EML5 FMN1 DMD GOLGA8A KLC1 PCNT

2.09e-058999915GO:0099513
GeneOntologyCellularComponentanchoring junction

MYH1 MYH2 CD2AP TRPC4 SH3GL1 RPS7 EPB41L3 DDX6 JAK1 DST BAIAP2L1 FMN1 DMD PARD3

2.00e-049769914GO:0070161
GeneOntologyCellularComponentmicrotubule

ENKUR CEP57L1 NCKAP5 OPA1 KIF7 DST EML5 GOLGA8A KLC1 PCNT

2.18e-045339910GO:0005874
GeneOntologyCellularComponentciliary basal body

TRAF3IP1 KIF7 CCDC88A AGBL2 ODAD3 PCNT

3.33e-04195996GO:0036064
GeneOntologyCellularComponentcell-cell junction

MYH1 MYH2 CD2AP TRPC4 EPB41L3 DDX6 DST BAIAP2L1 FMN1 PARD3

4.93e-045919910GO:0005911
GeneOntologyCellularComponentsperm flagellum

ATG16L1 ENKUR SEPTIN4 SEPTIN6 DDX6 PPP3CC

5.45e-04214996GO:0036126
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

ATG16L1 ENKUR TRAF3IP1 OPA1 DST TRAK2 ODAD3

7.81e-04317997GO:0032838
GeneOntologyCellularComponent9+2 motile cilium

ATG16L1 ENKUR SEPTIN4 SEPTIN6 DDX6 PPP3CC

9.49e-04238996GO:0097729
GeneOntologyCellularComponentmitochondrial outer membrane

AGPAT5 MAOB SEPTIN4 OPA1 AIFM1 DMD

1.01e-03241996GO:0005741
GeneOntologyCellularComponentaxon

SEPTIN4 CD2AP EPB41L3 OPA1 SEPTIN6 LSM1 DST SYN1 TRAK2 DMD PARD3 KLC1

1.02e-038919912GO:0030424
GeneOntologyCellularComponentcentriole

CCDC88A ROCK1 AGBL2 ODAD3 PCNT

1.36e-03172995GO:0005814
GeneOntologyCellularComponentmotile cilium

ATG16L1 ENKUR SEPTIN4 SEPTIN6 DDX6 PPP3CC PCNT

1.50e-03355997GO:0031514
GeneOntologyCellularComponentciliary tip

TRAF3IP1 KIF7 ODAD3

1.53e-0348993GO:0097542
GeneOntologyCellularComponentcytoplasmic region

ATG16L1 ENKUR TRAF3IP1 OPA1 DST TRAK2 ODAD3

1.63e-03360997GO:0099568
GeneOntologyCellularComponentA band

MYH1 MYH2 DST

1.92e-0352993GO:0031672
GeneOntologyCellularComponentcell cortex

MYH2 SEPTIN4 CD2AP TRPC4 SEPTIN6 DST PARD3

1.93e-03371997GO:0005938
GeneOntologyCellularComponentseptin complex

SEPTIN4 SEPTIN6

1.95e-0314992GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN4 SEPTIN6

1.95e-0314992GO:0005940
GeneOntologyCellularComponentorganelle outer membrane

AGPAT5 MAOB SEPTIN4 OPA1 AIFM1 DMD

2.13e-03279996GO:0031968
GeneOntologyCellularComponentouter membrane

AGPAT5 MAOB SEPTIN4 OPA1 AIFM1 DMD

2.21e-03281996GO:0019867
GeneOntologyCellularComponentciliary rootlet

ODAD3 KLC1

2.55e-0316992GO:0035253
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH2

2.55e-0316992GO:0005859
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN4 SEPTIN6

2.55e-0316992GO:0032156
GeneOntologyCellularComponentearly endosome membrane

INPP5B SH3GL1 SH3GL3 DTX3L OCRL

3.38e-03212995GO:0031901
DomainGOLGA6L

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

1.25e-0861024IPR026737
DomainGOLGA2L5

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA8A

3.56e-08181025PF15070
DomainGolgin_A

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA8A

3.56e-08181025IPR024858
DomainDEAD_ATP_HELICASE

DDX49 DDX6 DDX46 DDX21

2.36e-05311024PS00039
DomainRNA-helicase_DEAD-box_CS

DDX49 DDX6 DDX46 DDX21

3.04e-05331024IPR000629
DomainQ_MOTIF

DDX49 DDX6 DDX46 DDX21

4.82e-05371024PS51195
DomainRNA_helicase_DEAD_Q_motif

DDX49 DDX6 DDX46 DDX21

4.82e-05371024IPR014014
DomainSH3_1

CD2AP SH3GL1 SH3GL3 DST BAIAP2L1 SH3RF3

2.81e-041641026PF00018
DomainDEAD/DEAH_box_helicase_dom

DDX49 DDX6 DDX46 DDX21

6.84e-04731024IPR011545
DomainDEAD

DDX49 DDX6 DDX46 DDX21

6.84e-04731024PF00270
DomainP-loop_NTPase

MYH1 MYH2 TRIT1 DDX49 SEPTIN4 OPA1 SEPTIN6 DDX6 KIF7 DDX46 ABCA6 MTIF2 DDX21

7.08e-0484810213IPR027417
DomainKinase-like_dom

TLK2 MAP3K5 JAK1 TLK1 RNASEL DST ROCK1 PRKCQ DMD MAPK11

7.60e-0454210210IPR011009
DomainSH3

CD2AP SH3GL1 SH3GL3 DST BAIAP2L1 SH3RF3

1.20e-032161026PS50002
DomainIPPc

INPP5B OCRL

1.29e-03101022IPR000300
DomainIPPc

INPP5B OCRL

1.29e-03101022SM00128
DomainSH3_domain

CD2AP SH3GL1 SH3GL3 DST BAIAP2L1 SH3RF3

1.31e-032201026IPR001452
DomainSeptin

SEPTIN4 SEPTIN6

2.22e-03131022PF00735
DomainG_SEPTIN_dom

SEPTIN4 SEPTIN6

2.22e-03131022IPR030379
DomainG_SEPTIN

SEPTIN4 SEPTIN6

2.22e-03131022PS51719
DomainSeptin

SEPTIN4 SEPTIN6

2.57e-03141022IPR016491
DomainHelicase_C

DDX49 DDX6 DDX46 DDX21

2.81e-031071024PF00271
DomainHELICc

DDX49 DDX6 DDX46 DDX21

2.81e-031071024SM00490
DomainHelicase_C

DDX49 DDX6 DDX46 DDX21

2.91e-031081024IPR001650
DomainSpectrin_alpha_SH3

SH3GL1 SH3GL3

2.96e-03151022IPR013315
DomainBAR

SH3GL1 SH3GL3

2.96e-03151022SM00721
DomainMyosin_N

MYH1 MYH2

2.96e-03151022PF02736
DomainBAR

SH3GL1 SH3GL3

2.96e-03151022PF03114
DomainMyosin_N

MYH1 MYH2

2.96e-03151022IPR004009
DomainHELICASE_CTER

DDX49 DDX6 DDX46 DDX21

3.01e-031091024PS51194
DomainHELICASE_ATP_BIND_1

DDX49 DDX6 DDX46 DDX21

3.01e-031091024PS51192
DomainDEXDc

DDX49 DDX6 DDX46 DDX21

3.01e-031091024SM00487
DomainHelicase_ATP-bd

DDX49 DDX6 DDX46 DDX21

3.11e-031101024IPR014001
DomainBAR_dom

SH3GL1 SH3GL3

3.37e-03161022IPR004148
DomainS_TKc

TLK2 MAP3K5 TLK1 RNASEL ROCK1 PRKCQ MAPK11

3.54e-033591027SM00220
DomainPROTEIN_KINASE_ATP

TLK2 MAP3K5 JAK1 TLK1 RNASEL ROCK1 PRKCQ MAPK11

3.66e-034591028PS00107
DomainHEAT_type_2

PPP4R1 TEX10

3.81e-03171022IPR021133
DomainMyosin_tail_1

MYH1 MYH2

4.27e-03181022PF01576
DomainMyosin_tail

MYH1 MYH2

4.27e-03181022IPR002928
DomainBAR

SH3GL1 SH3GL3

4.75e-03191022PS51021
DomainMyosin-like_IQ_dom

MYH1 MYH2

4.75e-03191022IPR027401
Domain-

MYH1 MYH2

4.75e-031910224.10.270.10
DomainProtein_kinase_ATP_BS

TLK2 MAP3K5 JAK1 TLK1 ROCK1 PRKCQ MAPK11

4.76e-033791027IPR017441
DomainPkinase

TLK2 MAP3K5 TLK1 RNASEL ROCK1 PRKCQ MAPK11

4.90e-033811027PF00069
DomainProt_kinase_dom

TLK2 MAP3K5 JAK1 TLK1 RNASEL ROCK1 PRKCQ MAPK11

5.34e-034891028IPR000719
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP4R1 ATP5IF1 UGGT1 RPS7 TEX10 OPA1 KIF7 EFR3A PPP1R8 CCDC88A PPP3CC LMAN1 AIFM1 ROCK1 DMD MAPK11 DNAJA1 PCNT FBXW7

2.93e-1010491041927880917
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CD2AP RPS7 OCRL EPB41L3 OPA1 DDX6 EFR3A CCDC88A DST LMAN1 BAIAP2L1 AIFM1 PKM ROCK1 PARD3 DNAJA1

3.71e-107081041639231216
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TLK2 TRAF3IP1 TRPC4 EPB41L3 TEX10 OPA1 MAP3K5 KIF7 CCDC88A DST SYN1 ROCK1 PARD3 DNAJA1 GOLGA8A KLC1 PCNT

4.13e-099631041728671696
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

TLK2 PPP4R1 MYH2 ATG16L1 UGGT1 EPB41L3 OPA1 SEPTIN6 DDX6 JAK1 PPP1R8 TLK1 AIFM1 NOM1 PARD3 DDX21 DNAJA1 KLC1

4.74e-0812841041817353931
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

EPB41L3 EFR3A JAK1 CCDC88A AFAP1L2 DST BAIAP2L1 FMN1 ROCK1 DMD

2.10e-073771041038117590
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TLK2 DMTF1 DDX49 INPP5B UGGT1 CD2AP SH3GL3 CEP57L1 SEPTIN6 EML5 FMN1 ROCK1 PARD3 DDX21 PCNT

8.28e-0710841041511544199
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

UGGT1 RPS7 DTX3L TEX10 OPA1 DDX46 OXCT1 BAIAP2L1

1.29e-06262104836880596
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

AGPAT5 CD2AP SH3GL1 RPS7 OCRL SEPTIN6 KIF7 PPP1R8 CCDC88A BAIAP2L1 DNAJA1 KLC1 PCNT

1.66e-068531041328718761
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TLK2 ATG16L1 TRAF3IP1 OCRL OPA1 TUFT1 LSM1 KIF7 PPP1R8 TLK1 CCDC88A LMAN1 EML5 PARD3 SH3RF3 KLC1

1.96e-0613211041627173435
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

UGGT1 CD2AP SH3GL1 RPS7 EPB41L3 OPA1 DDX46 OXCT1 LMAN1 BAIAP2L1 GRHPR AIFM1 PKM ROCK1 DDX21 DNAJA1

3.03e-0613671041632687490
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

SEPTIN4 UGGT1 TEX10 TUFT1 LMAN1 PKM ROCK1 DMD

3.87e-06304104832235678
Pubmed

Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.

SH3GL1 SH3GL3 SYN1

4.21e-0611104312456676
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

PPP4R1 TRAF3IP1 CEP57L1 CCDC88A DST DMD

6.48e-06151104617043677
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

ATP5IF1 MAOB RPS7 EPB41L3 SEPTIN6 DDX6 OXCT1 PKM SYN1 DNAJA1

7.06e-065581041035063084
Pubmed

The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.

MYH1 MYH2 PRKCQ

7.27e-061310438948582
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

CD2AP SH3GL1 EPB41L3 DDX6 EFR3A DST BAIAP2L1 FMN1 PKM PARD3

7.87e-065651041025468996
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

CD2AP UTP23 ITIH5 AIFM1 PARD3 PCNT

8.71e-06159104630581152
Pubmed

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

CYP4A11 CYP4A22

8.86e-062104215611369
Pubmed

Myosin heavy chains IIa and IId are functionally distinct in the mouse.

MYH1 MYH2

8.86e-06210429585413
Pubmed

The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.

TLK2 TLK1

8.86e-062104221647934
Pubmed

Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.

MYH1 MYH2

8.86e-062104216575183
Pubmed

Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.

CYP4A11 CYP4A22

8.86e-062104223641057
Pubmed

Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.

TLK2 TLK1

8.86e-062104232755577
Pubmed

cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.

TLK2 TLK1

8.86e-06210429427565
Pubmed

The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.

CYP4A11 CYP4A22

8.86e-062104228912346
Pubmed

Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.

CYP4A11 CYP4A22

8.86e-062104224413902
Pubmed

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin.

CCDC88A PRKCQ

8.86e-062104223509302
Pubmed

Myosin heavy chain composition of the human genioglossus muscle.

MYH1 MYH2

8.86e-062104222337492
Pubmed

PKC theta ablation improves healing in a mouse model of muscular dystrophy.

PRKCQ DMD

8.86e-062104222348094
Pubmed

Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.

PRKCQ DMD

8.86e-062104228089792
Pubmed

X-inactivation analysis of embryonic lethality in Ocrl wt/-; Inpp5b-/- mice.

INPP5B OCRL

8.86e-062104220195868
Pubmed

Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

CYP4A11 CYP4A22

8.86e-06210428031839
Pubmed

Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.

CYP4A11 CYP4A22

8.86e-062104210860550
Pubmed

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.

CYP4A11 CYP4A22

8.86e-062104211320253
Pubmed

Different pathways regulate expression of the skeletal myosin heavy chain genes.

MYH1 MYH2

8.86e-062104211551968
Pubmed

Disrupted sperm function and fertilin beta processing in mice deficient in the inositol polyphosphate 5-phosphatase Inpp5b.

INPP5B OCRL

8.86e-062104211784089
Pubmed

Characterization of the CYP4A11 gene, a second CYP4A gene in humans.

CYP4A11 CYP4A22

8.86e-062104212464262
Pubmed

Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

CYP4A11 CYP4A22

8.86e-062104215066132
Pubmed

ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma.

JAK1 ROCK1

8.86e-062104221840487
Pubmed

Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice.

INPP5B OCRL

8.86e-06210429593760
Pubmed

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

CYP4A11 CYP4A22

8.86e-062104223825080
Pubmed

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

CYP4A11 CYP4A22

8.86e-062104216691295
Pubmed

The P450 gene superfamily: recommended nomenclature.

CYP4A11 CYP4A22

8.86e-06210423829886
Pubmed

Lack of PKCθ Promotes Regenerative Ability of Muscle Stem Cells in Chronic Muscle Injury.

PRKCQ DMD

8.86e-062104232023816
Pubmed

Control of Mitochondrial Remodeling by the ATPase Inhibitory Factor 1 Unveils a Pro-survival Relay via OPA1.

ATP5IF1 OPA1

8.86e-062104228228254
Pubmed

Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.

CYP4A11 CYP4A22

8.86e-062104229277328
Pubmed

OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells.

INPP5B OCRL

8.86e-062104225305077
Pubmed

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

CYP4A11 CYP4A22

8.86e-062104221820496
Pubmed

Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis.

ATP5IF1 PKM

8.86e-062104228183315
Pubmed

Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.

INPP5B OCRL

8.86e-062104227895154
Pubmed

Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle.

MYH1 MYH2

8.86e-06210427545970
Pubmed

Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

CYP4A11 CYP4A22

8.86e-062104220943934
Pubmed

Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.

INPP5B OCRL

8.86e-062104221183592
Pubmed

The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.

CYP4A11 CYP4A22

8.86e-06210422766933
Pubmed

Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase.

INPP5B OCRL

8.86e-062104219700499
Pubmed

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

CYP4A11 CYP4A22

8.86e-062104217112342
Pubmed

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

CCDC88A MTIF2

8.86e-062104224166409
Pubmed

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.

CYP4A11 CYP4A22

8.86e-062104230088983
Pubmed

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

CYP4A11 CYP4A22

8.86e-062104219208908
Pubmed

Targeting early PKCθ-dependent T-cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy.

PRKCQ DMD

8.86e-062104229214629
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TLK2 DDX49 TRAF3IP1 CD2AP TUFT1 DDX6 PPP1R8 TLK1 DDX46 AIFM1 PKM DDX21 DNAJA1 CNOT3

9.04e-0611551041420360068
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

DDX49 DDX6 DDX46 AIFM1 NOM1 PKM DDX21 DNAJA1 PCNT

1.60e-05486104930940648
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

TLK2 CCNL2 MYH1 MYH2 AGPAT5 TEX10 DDX6 JAK1 DST AIFM1 MAPK11 KLC1

1.83e-059101041236736316
Pubmed

Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.

CCDC88A PARD3 PCNT

2.05e-0518104329229865
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

RPS7 EPB41L3 JAK1 AIFM1 NOM1 PKM DDX21 DNAJA1

2.06e-05383104829331416
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

SH3GL1 DST SYN1 ROCK1 GOLGA8A

2.16e-05111104522558309
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CCDC30 INPP5B RPS7 OCRL EPB41L3 CCDC88A DST BAIAP2L1 NOM1 PKM PARD3

2.18e-057771041135844135
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH2

2.65e-053104226059207
Pubmed

Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.

CYP4A11 CYP4A22

2.65e-05310422354437
Pubmed

The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes.

MYH1 MAPK11

2.65e-053104217210568
Pubmed

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

TLK2 TLK1

2.65e-053104228535374
Pubmed

OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease.

INPP5B OCRL

2.65e-053104230590522
Pubmed

Molecular determinants of force production in human skeletal muscle fibers: effects of myosin isoform expression and cross-sectional area.

MYH1 MYH2

2.65e-053104225567808
Pubmed

Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.

CYP4A11 CYP4A22

2.65e-053104228270609
Pubmed

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.

INPP5B OCRL

2.65e-053104219536138
Pubmed

H19/Mir-130b-3p/Cyp4a14 potentiate the effect of praziquantel on liver in the treatment of Schistosoma japonicum infection.

CYP4A11 CYP4A22

2.65e-053104237659685
Pubmed

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.

MYH1 MYH2

2.65e-053104221470888
Pubmed

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.

CYP4A11 CYP4A22

2.65e-05310429271096
Pubmed

Vital function of PRELI and essential requirement of its LEA motif.

OPA1 AIFM1

2.65e-053104221364629
Pubmed

Structural and developmental analysis of two linked myosin heavy chain genes.

MYH1 MYH2

2.65e-05310421371481
Pubmed

Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.

CYP4A11 CYP4A22

2.65e-05310428011168
Pubmed

Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures.

ROCK1 PRKCQ

2.65e-05310429856983
Pubmed

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.

TLK2 TLK1

2.65e-053104238498025
Pubmed

Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases.

INPP5B OCRL

2.65e-053104224704254
Pubmed

Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4.

SEPTIN4 SEPTIN6

2.65e-053104216314519
Pubmed

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.

CYP4A11 CYP4A22

2.65e-05310421991046
Pubmed

Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence.

ROCK1 PRKCQ

2.65e-05310429516463
Pubmed

Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.

CYP4A11 CYP4A22

2.65e-053104219713718
Pubmed

Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver.

CYP4A11 CYP4A22

2.65e-053104215313227
Pubmed

OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP-mediated microtubule anchoring.

INPP5B OCRL

2.65e-053104233987909
Pubmed

Specific isomyosin proportions in hyperexcitable and physiologically denervated mouse muscle.

MYH2 DMD

2.65e-053104215013776
Pubmed

Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.

CD2AP ITIH5 EFR3A INTS10 DDX21 PCNT

2.85e-05196104619334288
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

ATP5IF1 MAP3K5 JAK1 DST AIFM1 PKM DDX21 DNAJA1

2.86e-05401104825852190
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

TRAF3IP1 CD2AP CCDC88A DST DMD

3.15e-05120104531413325
Pubmed

VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma.

RPS7 DDX6 AIFM1 PKM DNAJA1

3.41e-05122104536929488
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

MYH1 SH3GL1 RPS7 SEPTIN6 DDX46 DST PKM DMD KLC1

3.55e-05538104928524877
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CD2AP EPB41L3 PALB2 CCDC88A DST LMAN1 KLC1 PCNT

3.84e-05418104834709266
Pubmed

Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.

DDX6 GOLGA8A PCNT

3.84e-0522104334897463
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH2 DMD

3.84e-0522104324301466
Pubmed

Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.

MAP3K5 MAPK11 KLC1

3.84e-0522104315767678
InteractionDISC1 interactions

PPP4R1 TRAF3IP1 RPS7 CEP57L1 EPB41L3 DDX6 KIF7 JAK1 CCDC88A DST DMD DNAJA1 PCNT FBXW7

3.02e-0842910114int:DISC1
InteractionLYN interactions

CCNL2 ATG16L1 DDX49 EPB41L3 EFR3A PPP1R8 CCDC88A DST LMAN1 BAIAP2L1 ROCK1 PRKCQ DMD PARD3 DDX21 BANK1

5.63e-0772010116int:LYN
InteractionPML interactions

TLK2 UGGT1 CD2AP SH3GL1 RPS7 DTX3L EPB41L3 TEX10 OPA1 JAK1 TLK1 DDX46 OXCT1 BAIAP2L1 PKM MAPK11 FBXW7

3.65e-0693310117int:PML
InteractionKCNA3 interactions

CD2AP RPS7 OCRL EPB41L3 OPA1 DDX6 EFR3A CCDC88A DST LMAN1 BAIAP2L1 AIFM1 PKM ROCK1 PARD3 DNAJA1

6.60e-0687110116int:KCNA3
InteractionENKUR interactions

ENKUR OPA1 FBXW7

2.60e-05121013int:ENKUR
InteractionRCOR1 interactions

CD2AP EPB41L3 PALB2 TUFT1 DDX46 CCDC88A DST LMAN1 DNAJA1 KLC1 FBXW7

3.74e-0549410111int:RCOR1
InteractionYWHAE interactions

ATG16L1 EPB41L3 DDX6 MAP3K5 JAK1 TLK1 CCDC88A DST BAIAP2L1 GRHPR SYN1 ROCK1 PARD3 DDX21 DNAJA1 SH3RF3 KLC1 FBXW7

4.75e-05125610118int:YWHAE
InteractionPNLIPRP2 interactions

DDX6 DDX46 CYB5R4

5.32e-05151013int:PNLIPRP2
InteractionKDM1A interactions

ATG16L1 CD2AP EPB41L3 PALB2 SEPTIN6 TUFT1 CCDC88A DST LMAN1 DNAJA1 ODAD3 CNOT3 KLC1 PCNT FBXW7

6.78e-0594110115int:KDM1A
InteractionCYP4A22 interactions

CYP4A11 CYP4A22

7.44e-0531012int:CYP4A22
InteractionEXOC1 interactions

ATG16L1 TRAF3IP1 TUFT1 CCDC88A DST PCNT

8.37e-051431016int:EXOC1
InteractionSNAI1 interactions

RPS7 EPB41L3 PALB2 JAK1 AIFM1 NOM1 PKM GOLGA6L9 DDX21 DNAJA1 FBXW7

9.18e-0554610111int:SNAI1
InteractionITSN2 interactions

ATG16L1 SH3GL1 DST SYN1 ROCK1 GOLGA8A

9.75e-051471016int:ITSN2
InteractionDST interactions

ATP5IF1 TRAF3IP1 UGGT1 RPS7 DST LMAN1 PARD3 PCNT

9.87e-052871018int:DST
InteractionKIF15 interactions

ATG16L1 CD2AP JAK1 DMD DDX21

1.10e-04941015int:KIF15
InteractionMCAM interactions

EPB41L3 EFR3A JAK1 CCDC88A AFAP1L2 DST BAIAP2L1 FMN1 ROCK1 DMD

1.21e-0446810110int:MCAM
InteractionTRAF3IP1 interactions

TRAF3IP1 DST PKM DMD PCNT

1.22e-04961015int:TRAF3IP1
InteractionARHGAP17 interactions

CD2AP OPA1 DDX6 PARD3 KLC1

1.28e-04971015int:ARHGAP17
InteractionNF2 interactions

CCNL2 ATP5IF1 CD2AP SH3GL1 RPS7 MAP3K5 PPP1R8 PARD3 DNAJA1

1.32e-043831019int:NF2
Cytoband15q25.2

GOLGA6L4 GOLGA6L10 GOLGA6L9

1.27e-0443103315q25.2
CytobandEnsembl 112 genes in cytogenetic band chr15q25

SH3GL3 GOLGA6L4 GOLGA6L10 GOLGA6L9

4.80e-041601034chr15q25
GeneFamilyDEAD-box helicases

DDX49 DDX6 DDX46 DDX21

1.04e-0542594499
GeneFamilyN-BAR domain containing

SH3GL1 SH3GL3

6.77e-04125921289
GeneFamilySeptins

SEPTIN4 SEPTIN6

7.98e-0413592732
GeneFamilyMyosin heavy chains

MYH1 MYH2

1.07e-03155921098
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R8 NOM1 PARD3 PPP1R16A

2.88e-03181594694
GeneFamilyPhosphoinositide phosphatases

INPP5B OCRL

4.88e-03325921079
GeneFamilyCytochrome P450 family 4

CYP4A11 CYP4A22

6.14e-03365921003
GeneFamilyAnkyrin repeat domain containing

TRPC4 RNASEL BANK1 PPP1R16A

8.01e-03242594403
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EPB41L3 JAK1

1.16e-02505921293
CoexpressionCUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE

FRAS1 DST LMAN1 BCAP29 AIFM1 DMD GOLGA8A

6.17e-061791017M39308
CoexpressionHALLMARK_MITOTIC_SPINDLE

CD2AP TLK1 CCDC88A DST ROCK1 KLC1 PCNT

1.23e-051991017M5893
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TLK2 CD2AP OPA1 EFR3A TLK1 DST MTIF2 ROCK1 DMD PARD3 DDX21 KLC1 PCNT

2.53e-0585610113M4500
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PPP4R1 FILIP1 SH3GL3 NCKAP5 EPB41L3 TUFT1 DST PARD3

1.59e-08190104830b50d183d7649146eb1e79b47ba897355f1998a
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

FRAS1 MAOB TRPC4 ITIH5 DST ABCA6 PARD3

3.84e-071951047603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 MAOB TRPC4 ITIH5 DST ABCA6 SH3RF3

4.56e-072001047e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LINGO2 PLEKHD1 ABCA6 IL1RAPL2 FMN1 GOLGA8A

1.81e-0615610464d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 FRAS1 SH3GL3 GSAP EPB41L3 MAP3K5

3.75e-0617710469af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD SH3RF3

4.69e-061841046c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

FILIP1 SH3GL3 NCKAP5 EPB41L3 DST GOLGA8A

4.84e-0618510461c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 GSAP EPB41L3 EML5 BAIAP2L1 PRKCQ

4.99e-0618610464e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 GSAP EPB41L3 MAP3K5 BAIAP2L1 PRKCQ

5.15e-06187104658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB OCRL EPB41L3 DDX6 CCDC88A DST

5.81e-061911046b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 MAOB UGGT1 EPB41L3 DST PARD3

5.99e-0619210465b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD SH3RF3

6.35e-06194104681713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD SH3RF3

6.35e-061941046cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD SH3RF3

6.35e-061941046ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD SH3RF3

6.35e-061941046627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 MAP3K5 DST ABCA6 SH3RF3

6.54e-061951046d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SH3GL3 NCKAP5 EPB41L3 TUFT1 DST GOLGA8A

6.94e-06197104669d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SH3GL3 NCKAP5 EPB41L3 TUFT1 DST GOLGA8A

6.94e-061971046e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCell(5)_Fibroblasts-(5)_Fibroblast-G|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FILIP1 FRAS1 MAOB SEPTIN4 DST ABCA6

6.94e-061971046a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FILIP1 FRAS1 MAOB SEPTIN4 DST ABCA6

7.35e-061991046b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FILIP1 FRAS1 MAOB SEPTIN4 DST ABCA6

7.35e-061991046212e89d097753790061310373a1fafba773488b6
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

FILIP1 TRPC4 DST ABCA6 DMD SH3RF3

7.35e-0619910469503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FILIP1 FRAS1 MAOB SEPTIN4 DST ABCA6

7.35e-06199104614b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLK2 DTX3L DDX6 ROCK1 DDX21 GOLGA8A

7.56e-06200104612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 MAOB TRPC4 DST ABCA6 SH3RF3

7.56e-06200104634f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPS7 SEPTIN6 JAK1 PPP3CC PRKCQ

5.66e-051751045f949613ee45f5d950578c512d197716855118d18
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ITIH5 MAP3K5 DMD

5.98e-051771045a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ITIH5 MAP3K5 DMD

5.98e-0517710453645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|356C / Donor, Lineage, Cell class and subclass (all cells)

AGPAT5 CEP57L1 ITIH5 SYCE1L GOLGA8A

6.30e-051791045f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 SH3GL3 GSAP EPB41L3 BAIAP2L1

6.64e-051811045b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

NCKAP5 OXCT1 ABCA6 DMD MAPK11

6.64e-0518110455a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCelldroplet-Lung-nan-21m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 JAK1 PPP3CC PRKCQ

6.82e-0518210450fbc70527059cab8be16ae7348c791dfff159604
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 LINGO2 DST DMD FBXW7

6.82e-051821045ecb5624c9074cc6449fad961df54c926c2681d54
ToppCelldroplet-Lung-nan-21m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 JAK1 PPP3CC PRKCQ

6.82e-0518210454d27bd13d5507862e8cca5def655f93b5c919a0e
ToppCelldroplet-Lung-nan-21m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 PPP3CC PRKCQ BANK1

7.00e-051831045d03a35fd69a1307b99928b73fd5879aed2fda2b5
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 CD2AP GSAP EPB41L3 BAIAP2L1

7.18e-05184104542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PPP4R1 SH3GL3 NCKAP5 DST PARD3

7.18e-05184104557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

SH3GL3 NCKAP5 DST DMD GOLGA8A

7.18e-051841045561592edc3083fad41b91811151b442207c65dd9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 EML5 BAIAP2L1 FMN1 PRKCQ

7.18e-051841045ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PPP4R1 SH3GL3 NCKAP5 DST PARD3

7.18e-051841045d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 PPP3CC PRKCQ BANK1

7.37e-051851045c9ab7a3584d25f0ed73b20919c3dba00f502eac4
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENKUR SEPTIN4 ABCA6 DMD PARD3

7.37e-051851045709236097cbfc254796fcc69b5f5178b73dad9bd
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENKUR SEPTIN4 ABCA6 DMD PARD3

7.37e-051851045af078a6c4a3e0b54b7d8ab7b30dcd06053ebfd28
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 TRPC4 LINGO2 AFAP1L2 IL1RAPL2

7.37e-05185104556c7a0dbf141728ac76b8c90af197719942ca67c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 GSAP BAIAP2L1 FMN1 PRKCQ

7.56e-051861045e83718fabb057100835d3357df407f283d23fe16
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FILIP1 FRAS1 SH3GL3 NCKAP5 GOLGA8A

7.75e-0518710454ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CEP57L1 ITIH5 MAP3K5 SYCE1L GOLGA8A

7.75e-051871045c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

FRAS1 MAOB TRPC4 DST ABCA6

7.75e-05187104592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ENKUR CCDC30 CAPS2 AGBL2 ODAD3

7.75e-051871045a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

TRAF3IP1 CD2AP CCDC88A NOM1 CNOT3

7.75e-051871045d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ITIH5 DST ABCA6 DMD SH3RF3

7.75e-051871045bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

MAOB CYP4A11 NCKAP5 EPB41L3 DNAJA1

7.75e-051871045acd305475f3609800af0d7bc68d83ef41228080b
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 PKM PRKCQ MAPK11 DNAJA1

7.95e-051881045e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

SH3GL3 NCKAP5 TUFT1 PARD3 GOLGA8A

7.95e-051881045be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AFAP1L2 PPP3CC DNAJA1 BANK1 FBXW7

7.95e-0518810459858940c616e43441644c5a3bea8d832ee4daf79
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ENKUR CCDC30 CAPS2 AGBL2 ODAD3

7.95e-051881045e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 FRAS1 ITIH5 IL1RAPL2 DMD

7.95e-051881045879de94924de978478696fc7838e05a4d795b905
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD

8.15e-05189104571397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD

8.15e-0518910454eea4759520c312bd17a681034d8074e47093d2b
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.15e-05189104538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.15e-051891045a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN4 ITIH5 JAK1 DST BANK1

8.35e-051901045d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ITIH5 MAP3K5 DMD

8.35e-0519010455681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 ABCA6 DMD SH3RF3

8.56e-051911045a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellfacs-MAT-Fat-3m-Lymphocytic-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 PPP3CC PRKCQ BANK1

8.56e-051911045530469909ab0994bece37945e9098359077b0824
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.56e-051911045bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.56e-0519110456880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FRAS1 SEPTIN4 ITIH5 DST ABCA6

8.56e-051911045e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 MAOB UGGT1 EPB41L3 DST

8.56e-051911045f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

8.56e-05191104539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellfacs-MAT-Fat-3m-Lymphocytic|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS7 SEPTIN6 PPP3CC PRKCQ BANK1

8.56e-051911045f7a81acb938ce5d383326840dd45f7dd2cf12b1d
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FRAS1 SEPTIN4 ITIH5 DST ABCA6

8.56e-0519110451726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 ABCA6 DMD SH3RF3

8.56e-0519110458f6d592edc32fdb901af30501d4360512334e8c2
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.56e-05191104596483adb97c81208aa513782550acd8a08b63866
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

8.56e-051911045ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.77e-051921045b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENKUR TRAF3IP1 CCDC30 AGBL2 ODAD3

8.77e-0519210452d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

8.99e-051931045f1199518c3626fd29bfce65070dd21a660671213
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

DST ABCA6 DMD PARD3 SH3RF3

8.99e-051931045e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MAOB SEPTIN4 TRPC4 NCKAP5 DST

8.99e-0519310455896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB UGGT1 EPB41L3 DST PKM

9.21e-05194104592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SEPTIN4 TRPC4 ABCA6 DMD

9.21e-051941045e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellControl-cDC-|Control / Disease condition and Cell class

NCKAP5 SEPTIN6 OXCT1 DST BANK1

9.44e-051951045a2b4d9473eff73f088b247ce43e66f013622471e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.44e-051951045cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NCKAP5 CCDC88A DST PKM PPP1R16A

9.44e-0519510450fcc41cda3e5f921748cf7e7fe48dd7ca1de4636
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.44e-051951045783bfa8110161cbd6def50ce849cae676c39c458
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 UGGT1 EPB41L3 DST PKM

9.44e-0519510453e519cffa6144a62b06124642a14c9ff39b76554
ToppCellControl-cDC|Control / Disease condition and Cell class

NCKAP5 SEPTIN6 OXCT1 DST BANK1

9.44e-051951045b96acdd22dd3885af69328f170ea871a0d570034
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 UGGT1 EPB41L3 DST PKM

9.44e-0519510457796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FILIP1 FRAS1 MAOB ITIH5 DST

9.67e-0519610456730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FILIP1 FRAS1 MAOB ITIH5 DST

9.67e-05196104521dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.67e-0519610453a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.67e-051961045bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MAOB SEPTIN4 DST ABCA6

9.90e-051971045156155c2f0c1a2461e45803da578af18ee221660
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 CD2AP BAIAP2L1 PKM PARD3

9.90e-0519710457e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SH3GL3 NCKAP5 EPB41L3 DST GOLGA8A

9.90e-0519710458d5097898dd01cedb04cb694cb480c931e08462c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.90e-051971045ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 TRPC4 ABCA6 DMD SH3RF3

9.90e-05197104537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MAOB SEPTIN4 DST ABCA6

9.90e-051971045d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

FILIP1 GSAP LMAN1 BAIAP2L1 PRKCQ

9.90e-0519710451a1bee8da6e04b65935c40373eaee4d6c046d9a1
Diseasedisintegrin and metalloproteinase domain-containing protein 11 measurement

RPS7 ITIH5

1.11e-045992EFO_0801529
DiseaseX-14939 measurement

CYP4A11 CYP4A22

1.66e-046992EFO_0800747
DiseaseMalignant neoplasm of breast

MYH1 TRPC4 RPS7 DTX3L EPB41L3 PLEKHD1 PALB2 IL1RAPL2 PLD2 DMD CYB5R4 FBXW7

2.55e-0410749912C0006142
DiseaseRetinal Pigment Epithelial Detachment

AIFM1 PRKCQ

3.95e-049992C0339546
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0080719 (implicated_via_orthology)
Diseaseage at onset, multiple sclerosis

NCKAP5 AXDND1

4.93e-0410992EFO_0004847, MONDO_0005301
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH2

4.93e-0410992DOID:0111596 (implicated_via_orthology)
DiseaseRetinal Detachment

AIFM1 PRKCQ

6.01e-0411992C0035305
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CYP4A11 CYP4A22

6.01e-0411992DOID:0110861 (biomarker_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH2

7.20e-0412992DOID:11720 (implicated_via_orthology)
DiseaseAkinetic-Rigid Variant of Huntington Disease

MAOB AIFM1

7.20e-0412992C0751207
DiseaseJuvenile Huntington Disease

MAOB AIFM1

7.20e-0412992C0751208
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH2

7.20e-0412992DOID:2106 (implicated_via_orthology)
DiseaseHuntington Disease, Late Onset

MAOB AIFM1

7.20e-0412992C0393574
Diseasepolychlorinated biphenyls measurement, gestational serum measurement

NCKAP5 FMN1

7.20e-0412992EFO_0007042, EFO_0007964
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH2

8.48e-0413992DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH2

1.14e-0315992DOID:0050646 (implicated_via_orthology)
Diseaseidiopathic scoliosis (implicated_via_orthology)

KIF7 ODAD3

1.30e-0316992DOID:0060250 (implicated_via_orthology)
DiseaseHuntington Disease

MAOB AIFM1

1.47e-0317992C0020179
DiseaseCardiomyopathies, Primary

MAP3K5 DMD MAPK11

1.63e-0369993C0033141
DiseaseMyocardial Diseases, Secondary

MAP3K5 DMD MAPK11

1.63e-0369993C0036529
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH2 PPP3CC

1.77e-0371993DOID:0050700 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in very small VLDL percentage

INTS10 ABCA6 BANK1

1.77e-0371993EFO_0022259
Diseasephospholipids in large HDL measurement

INTS10 AGBL2 BANK1

1.92e-0373993EFO_0022190
Diseasecerebellum white matter volume change measurement, age at assessment

LINGO2 EPB41L3

2.04e-0320992EFO_0008007, EFO_0021498
Diseasealkaline phosphatase measurement

ATG16L1 AGPAT5 RPS7 PLEKHD1 DDX6 JAK1 TLK1 BAIAP2L1 ABCA6 BCAP29

2.18e-0310159910EFO_0004533
Diseasebreast carcinoma

CCDC30 SUMO1P1 EPB41L3 PALB2 INTS10 BAIAP2L1 TRAK2 DMD KLC1 PCNT

2.24e-0310199910EFO_0000305
Diseasefumarate measurement

AFAP1L2 PPP1R16A

2.24e-0321992EFO_0010480
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 DMD

2.50e-0380993DOID:12930 (implicated_via_orthology)
Diseasehigh density lipoprotein particle size measurement

INTS10 BAIAP2L1 AGBL2 BANK1

2.62e-03170994EFO_0008592
Diseaseremission, hepatitis C virus infection

SEPTIN6 PARD3

2.69e-0323992EFO_0003047, EFO_0009785
Diseasemental or behavioural disorder

DMTF1 NCKAP5 PRKCQ DMD

3.15e-03179994EFO_0000677

Protein segments in the cluster

PeptideGeneStartEntry
EHLGDKIKDEDIKLR

SUMO1P1

11

G2XKQ0
AERHGHKELKKIFED

BANK1

386

Q8NDB2
ILDLIKKGVAKVDHV

DDX6

226

P26196
IQDVLKEKLHKRGVR

CAPS2

431

Q9BXY5
IKLKDGRKVETDHIV

AIFM1

381

O95831
KHQEELTELHKKRGE

ATG16L1

91

Q676U5
AKIKGIHLKEVEQEV

ABCA6

581

Q8N139
RILHKGEELAKLEAK

AFAP1L2

416

Q8N4X5
EKERLEKKKEEIRGH

AFAP1L2

671

Q8N4X5
EKKKEEIRGHLAQLR

AFAP1L2

676

Q8N4X5
KEGELEKIKRKRHLD

CYP4A11

276

Q02928
EKLKRILKSHGKDEE

BCAP29

156

Q9UHQ4
IVEALKKDHGKELEK

CD2AP

596

Q9Y5K6
LQDHLEKVKALRGEI

DMD

2971

P11532
IVREKKILEVHIDKG

DNAJA1

201

P31689
EIEKLKELRIKHGND

DMTF1

231

Q9Y222
HVIQEILGHLDARKK

EFR3A

291

Q14156
DKQDRIEGLKRHIEK

CNOT3

161

O75175
ILHLKREHKEEIENL

FMN1

726

Q68DA7
GNHIADLKKEIEILR

JAK1

916

P23458
GDVEIDRNKHIHKKR

INTS10

356

Q9NVR2
KVNEVERLIHHVKGK

MAOB

81

P27338
KVELEKEDGLVLHKR

TRIT1

151

Q9H3H1
LEEEEKHGGLVKKIL

TRAF3IP1

531

Q8TDR0
ELRLLKHLKHENVIG

MAPK11

71

Q15759
KLDNILLDKDGHIKI

PRKCQ

506

Q04759
KDLLLVKEKEGVLHV

FRAS1

2921

Q86XX4
GQEDLKIIEEKRKEH

MTIF2

456

P46199
EIIIAGKLVDRKLDH

ITIH5

511

Q86UX2
GKLVDRKLDHLHVEV

ITIH5

516

Q86UX2
KRKHVVKEVLGEHIV

EIF1AD

6

Q8N9N8
HKDIIDDLVKSGHKI

DST

5881

Q03001
KNLEVGIRKKIEHDV

C19orf53

51

Q9UNZ5
EKLTHELEKIGLNKE

CCDC88A

926

Q3V6T2
ELEKIGLNKERLLHD

CCDC88A

931

Q3V6T2
IEDIDKKHLVLLRDG

LSM1

11

O15116
GKRIHELEKIKKQVE

MYH2

1526

Q9UKX2
ELGEELHKREAILAK

KIF7

931

Q2M1P5
FIDIKEHLHIVKRDI

LMAN1

436

P49257
VHEVRKVLGEKGKNI

PKM

251

P14618
KIREKKLQHLLVDEG

LINGO2

411

Q7L985
EEKKHEIHLVQKLGR

GOLGA6L3

121

A6NEY3
EEKKHEIHLVQKLGR

GOLGA6L4

121

A6NEF3
EEKKHEIHLVQKLGR

GOLGA6L9

121

A6NEM1
EEKKHEIHLVQKLGR

GOLGA6L10

121

A6NI86
EEKKHEIHLVQKLGR

GOLGA6L19

121

H0YKK7
AEGGKRIHELEKIKK

MYH1

1521

P12882
ILTQELEKLKRKHEG

PCNT

1011

O95613
KLHIKTHLDEETGEK

PALB2

81

Q86YC2
LVLQKDDKGIHHRKL

OPA1

246

O60313
DHFLRHLQGVEKKKI

GSAP

616

A4D1B5
FHKEIIHELEKKIEL

BAIAP2L1

96

Q9UHR4
RVLKKGEHQILVDEK

DTX3L

66

Q8TDB6
RKKVDLTHLEGEVEK

CCNL2

286

Q96S94
LTHLEGEVEKRKHAI

CCNL2

291

Q96S94
EKLHHTLIKNKDLEE

AXDND1

951

Q5T1B0
KEGELEKIKRKRHLD

CYP4A22

276

Q5TCH4
DHLALDEIKKRGIRV

GRHPR

86

Q9UBQ7
KEEGIDEPLHIKRRK

FBXW7

326

Q969H0
EIGILQHKIEKEKAI

CCDC30

536

Q5VVM6
KELLRQEIHKKFHEL

AGBL2

681

Q5U5Z8
QLEHDIGIIEKHKII

ENKUR

236

Q8TC29
KIEDILVLHLDRGKD

INPP5B

756

P32019
DIHLVHAIEEQIKKK

DDX49

356

Q9Y6V7
IKHLEEKLKEEEHQR

CEP57L1

196

Q8IYX8
VVHIKDRKEAIHELK

EML5

401

Q05BV3
EEIVHHKKEIERLQK

ATP5IF1

76

Q9UII2
EEEKKFLKLLELLGH

DDX46

601

Q7L014
GKLDLTKLKHVVLDE

DDX21

326

Q9NR30
KELEDKVIELHKSHR

EPB41L3

261

Q9Y2J2
KRALEIREKVLGKDH

KLC1

321

Q07866
LLVKRLEKGGKAEHE

PARD3

301

Q8TEW0
HRAIEEKDQEIKHLK

MAP3K5

1271

Q99683
LKEEKKHDTHRVEEL

GOLGA8A

286

A7E2F4
KGKKIHGEIDIKVEQ

SYN1

131

P17600
EKESIKHLKEEQGLV

UTP23

171

Q9BRU9
VKLDGSRLIKVHLDK

RPS7

146

P62081
LKDLDEVRIGVLKHL

PPP4R1

711

Q8TF05
GLHLDVVKGDKLIEK

PPP1R8

26

Q12972
HKKRKIREEIEHFGI

SEPTIN4

301

O43236
LKEIGHHLKKLEGRR

SH3GL3

151

Q99963
HHSKELRLEVEKLQK

FILIP1

416

Q7Z7B0
IKESHILEGLRKLQK

NCKAP5

396

O14513
LLRKSEKEEHRKLGL

TAF1A

316

Q15573
RLLKEHLGEKEVELA

IL1RAPL2

301

Q9NP60
VAELHKKIQLLEGDR

ODAD3

71

A5D8V7
GDEEVRAKLLELKHK

PPP1R16A

306

Q96I34
IRNLGEHIDEEKHKK

RNASEL

666

Q05823
DGEKHFLIKILNKIE

SHOC1

751

Q5VXU9
EELERLKKHVKGLLN

NOM1

356

Q5C9Z4
VHRLIKGEKYEKRIE

OXCT1

266

P55809
LNGEKVHLEEVLGKK

SYCE1L

86

A8MT33
VHLEEVLGKKQEALR

SYCE1L

91

A8MT33
KGRLIEVTEEELKKH

CYB5R4

51

Q7L1T6
EKELHEKFDRLKKLH

SEPTIN6

361

Q14141
DKIEDILVLHLDRGK

OCRL

651

Q01968
KELKERIFGKDEHVL

SIX6OS1

251

Q8N1H7
EEIFKLRLGHLKKEE

TLK2

406

Q86UE8
VLKNHLVKEGRLEEE

PPP3CC

41

P48454
IVDLQHKLKEHVIEK

TRAK2

291

O60296
TLEKEVAGLREKIHH

TUFT1

276

Q9NNX1
EIFKLRLGHLKKEEA

TLK1

401

Q9UKI8
LKEIQHHLKKLEGRR

SH3GL1

151

Q99961
LKGVEQEKKELRHLT

PLEKHD1

226

A6NEE1
EIELKEGDIVFVHKK

SH3RF3

841

Q8TEJ3
IEKGEAEHLRKRDKL

TEX10

811

Q9NXF1
HDEKKIIKDILKDRG

PRPF40B

556

Q6NWY9
EEVKHLKHNLEKVEG

ROCK1

636

Q13464
PKIHIHIDRIDKKDV

AGPAT5

256

Q9NUQ2
KVGDEIVDRILKAHK

PLD2

656

O14939
KEVVGAVELLLNHKK

TRPC4

106

Q9UBN4
DLEGQLKELRKHLVE

UGGT1

296

Q9NYU2