Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 PIAS3 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 TRIM5 RNF151 TRIM32 RFPL3

1.24e-0639823518GO:0061659
GeneOntologyMolecularFunctionubiquitin protein ligase activity

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 TRIM5 RNF151 TRIM32 RFPL3

2.15e-0637223517GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 PIAS3 RNF141 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RFPL3

3.01e-0651223520GO:0019787
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 RNF141 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RFPL3

3.59e-0647323519GO:0004842
GeneOntologyMolecularFunctionacyltransferase activity

NHLRC1 NAT1 TRAF6 TRIM61 BFAR KAT2A TRIM6 TRIM22 PIAS3 CIITA RNF141 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 ZDHHC4 TRIM5 RBCK1 RNF151 TRIM32 ZDHHC9 RFPL3

5.25e-0677523525GO:0016746
GeneOntologyMolecularFunctionaminoacyltransferase activity

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 PIAS3 RNF141 NFX1 PRPF19 MARCHF1 TRIM15 ITCH RNF19A RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RFPL3

5.33e-0653223520GO:0016755
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3C RIMBP3 RIMBP3B

1.58e-0552353GO:0030156
GeneOntologyMolecularFunctionzinc ion binding

TRAF6 TRIM61 ZFAND2B MBD1 ZNF205 TAB2 TRIM6 TRIM22 PIAS3 ZFR2 NFX1 MARCHF1 TRIM15 CAD ADAMTS4 RNF19A TRIM5 RNF151 SETDB2 L3MBTL1 CTCF TRIM32 DPF3 ZFHX2 RNF207 DNPEP

1.96e-0589123526GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

TRAF6 TRIM61 ZFAND2B MBD1 ZNF205 TAB2 TRIM6 TRIM22 PIAS3 ZFR2 NFX1 MARCHF1 MGAT5B TRIM15 CAD ADAMTS4 RNF19A RIOX1 TRIM5 RNF151 SETDB2 L3MBTL1 CTCF TRIM32 DPF3 AOC3 ZFHX2 RNF207 DNPEP

1.61e-04118923529GO:0046914
GeneOntologyMolecularFunctioncalcium ion binding

PCDHB5 DNER LRP1B FBLN1 CPNE6 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 PCDHB14 PCDHB13 PCDHB8 SNED1 SLIT1 AOC3 LRP2 FBN3 CRB2

2.21e-0474923521GO:0005509
GeneOntologyMolecularFunctionNotch binding

DNER NOTCH1 NOTCH4 SNED1

2.65e-04272354GO:0005112
GeneOntologyMolecularFunctionextracellular matrix structural constituent

CHI3L1 SSPOP FBLN1 FBN1 FBN2 LTBP4 HSPG2 LAMB2 FBN3

4.00e-041882359GO:0005201
GeneOntologyBiologicalProcessprotein polyubiquitination

NHLRC1 TRAF6 BFAR TRIM6 TRIM22 PRPF19 MARCHF1 DCAF15 ITCH RNF19A RFPL1 TRIM5 RBCK1 TRIM32 RFPL3

1.24e-0628923515GO:0000209
GeneOntologyBiologicalProcesspositive regulation of NF-kappaB transcription factor activity

TRAF6 TRIM6 TRIM22 TRIM15 NTRK1 RFPL1 TRIM5 RBCK1 TRIM32 RFPL3

9.38e-0615123510GO:0051092
GeneOntologyBiologicalProcessinterleukin-17-mediated signaling pathway

TRAF6 IL17RA NOTCH1 TRIM32

1.08e-05132354GO:0097400
GeneOntologyBiologicalProcessregulation of DNA-binding transcription factor activity

STK36 TRAF6 TRIM6 TRIM22 ADCY1 MEN1 NFKBIA NLRC5 ADGRF1 TRIM15 ITCH NTRK1 RFPL1 TRIM5 RBCK1 TRIM32 RFPL3

1.68e-0544923517GO:0051090
GeneOntologyBiologicalProcessprotein ubiquitination

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 ASB18 RNF141 NFX1 PRPF19 MARCHF1 DCAF15 TRIM15 ITCH RNF19A FBXL15 RFPL1 TRIM5 RBCK1 RNF151 TGFBR1 FBH1 TRIM32 RFPL3

1.99e-0581123524GO:0016567
GeneOntologyBiologicalProcessregulation of biological process involved in symbiotic interaction

TRIM6 TRIM22 FBLN1 CIITA RFPL1 TRIM5 RFPL3

2.34e-05752357GO:0043903
GeneOntologyBiologicalProcessaxon guidance

LAMC3 SEMA5B NOTCH1 NOTCH3 SEMA6C HSPG2 NTRK1 LAMB2 TGFB2 PLEKHG4B ARHGEF40 SLIT1 LRP2

2.54e-0528523513GO:0007411
GeneOntologyBiologicalProcessviral process

PCSK5 TRIM6 TRIM22 ITGB7 FBLN1 CIITA PARP16 NOTCH1 TRIM15 ITCH YTHDC2 RFPL1 TRIM5 EGFR TRIM32 ZDHHC9 RFPL3

2.55e-0546423517GO:0016032
GeneOntologyBiologicalProcessprotein K63-linked ubiquitination

TRAF6 BFAR TRIM22 PRPF19 ITCH TRIM5 TRIM32

2.55e-05762357GO:0070534
GeneOntologyBiologicalProcessneuron projection guidance

LAMC3 SEMA5B NOTCH1 NOTCH3 SEMA6C HSPG2 NTRK1 LAMB2 TGFB2 PLEKHG4B ARHGEF40 SLIT1 LRP2

2.63e-0528623513GO:0097485
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 ASB18 PIAS3 RNF141 NFX1 PRPF19 MARCHF1 DCAF15 TRIM15 ITCH RNF19A FBXL15 RFPL1 TRIM5 RBCK1 RNF151 TGFBR1 FBH1 TRIM32 RFPL3

3.33e-0589323525GO:0032446
GeneOntologyBiologicalProcessregulation of viral entry into host cell

TRIM6 TRIM22 CIITA RFPL1 TRIM5 RFPL3

3.73e-05552356GO:0046596
GeneOntologyBiologicalProcesspost-translational protein modification

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 ASB18 PIAS3 PARP16 RNF141 NFX1 PRPF19 MARCHF1 DCAF15 TRIM15 ITCH RNF19A FBXL15 RFPL1 TRIM5 RBCK1 RNF151 TGFBR1 FBH1 TRIM32 FLCN RFPL3 WIPI2

3.92e-05107423528GO:0043687
GeneOntologyBiologicalProcesspositive regulation of DNA-binding transcription factor activity

TRAF6 TRIM6 TRIM22 ADCY1 ADGRF1 TRIM15 NTRK1 RFPL1 TRIM5 RBCK1 TRIM32 RFPL3

4.82e-0526123512GO:0051091
GeneOntologyBiologicalProcessregulation of viral process

TRIM6 TRIM22 FBLN1 CIITA NOTCH1 TRIM15 RFPL1 TRIM5 TRIM32 RFPL3

5.66e-0518623510GO:0050792
GeneOntologyBiologicalProcessnon-canonical NF-kappaB signal transduction

TRAF6 TAB2 CHI3L1 TRIM6 NFKBIA TRIM15 UACA RBCK1 EGFR

5.72e-051502359GO:0038061
GeneOntologyBiologicalProcessmodulation by symbiont of entry into host

TRIM6 TRIM22 CIITA RFPL1 TRIM5 RFPL3

7.40e-05622356GO:0052372
GeneOntologyBiologicalProcessartery morphogenesis

GJA5 NOTCH1 NOTCH3 NOTCH4 TGFB2 TGFBR1 LRP2

8.78e-05922357GO:0048844
GeneOntologyBiologicalProcesspositive regulation of cardiac epithelial to mesenchymal transition

NOTCH1 TGFB2 TGFBR1

1.17e-0492353GO:0062043
GeneOntologyBiologicalProcessnegative regulation of epithelial cell differentiation

NOTCH1 NOTCH4 GDF3 TGFB2 TGFBR1 FRZB

1.35e-04692356GO:0030857
GeneOntologyBiologicalProcesssymbiont entry into host cell

TRIM6 TRIM22 ITGB7 CIITA ITCH RFPL1 TRIM5 EGFR RFPL3

1.43e-041692359GO:0046718
GeneOntologyBiologicalProcessartery development

GJA5 NOTCH1 NOTCH3 NOTCH4 FUZ TGFB2 TGFBR1 LRP2

1.45e-041332358GO:0060840
GeneOntologyBiologicalProcesscellular response to interleukin-17

TRAF6 IL17RA NOTCH1 TRIM32

1.46e-04242354GO:0097398
GeneOntologyBiologicalProcessviral life cycle

PCSK5 TRIM6 TRIM22 ITGB7 CIITA NOTCH1 TRIM15 ITCH YTHDC2 RFPL1 TRIM5 EGFR RFPL3

1.52e-0434023513GO:0019058
GeneOntologyBiologicalProcesscoronary artery morphogenesis

NOTCH1 TGFBR1 LRP2

1.65e-04102353GO:0060982
GeneOntologyBiologicalProcesspositive regulation of autophagy

TRIM6 TRIM22 RAB3GAP2 RFPL1 TRIM5 TRIM32 FLCN RFPL3 RUFY4

1.71e-041732359GO:0010508
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

MBD1 BCL6 TRIM6 MEN1 FBN1 PIAS3 NFKBIA USH2A NOTCH1 NOTCH3 NOTCH4 SEMA6C FUZ CTDSP1 RIOX1 GDF3 ADAMTS12 TGFB2 TGFBR1 EGFR FRZB SLIT1 FLCN

1.77e-0487523523GO:0045596
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CD109 MEN1 FBN1 FBN2 LTBP4 NOTCH1 FBXL15 GDF3 TGFB2 TGFBR1 LRP2 FLCN CRB2

1.86e-0434723513GO:0090092
GeneOntologyBiologicalProcesssymbiont entry into host

TRIM6 TRIM22 ITGB7 CIITA ITCH RFPL1 TRIM5 EGFR RFPL3

1.94e-041762359GO:0044409
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 ASB18 PIAS3 RNF141 NFX1 PRPF19 MARCHF1 DCAF15 TRIM15 ITCH RNF19A FBXL15 RFPL1 TRIM5 RBCK1 RNF151 TGFBR1 FBH1 TRIM32 RFPL3

2.28e-04100923525GO:0070647
GeneOntologyBiologicalProcessresponse to interleukin-17

TRAF6 IL17RA NOTCH1 TRIM32

2.35e-04272354GO:0097396
GeneOntologyBiologicalProcessprotein autoubiquitination

TRAF6 BFAR RNF141 NFX1 ITCH TRIM5

2.66e-04782356GO:0051865
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

CD109 MEN1 FBN1 FBN2 LTBP4 NOTCH1 FUZ FBXL15 GDF3 ADAMTS12 FGFBP3 LRP2 FLCN CRB2

2.88e-0441223514GO:0090287
GeneOntologyBiologicalProcessbiological process involved in interaction with host

TRIM6 TRIM22 ITGB7 FBLN1 CIITA ITCH RFPL1 TRIM5 EGFR RFPL3

3.00e-0422823510GO:0051701
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

MEN1 NOTCH1 FBXL15 TGFB2 TGFBR1 FLCN CRB2

3.52e-041152357GO:0090100
GeneOntologyBiologicalProcessregulation of viral life cycle

TRIM6 TRIM22 CIITA NOTCH1 TRIM15 RFPL1 TRIM5 RFPL3

4.30e-041562358GO:1903900
GeneOntologyBiologicalProcessheart development

PCSK5 IFT140 MBD1 TAB2 KAT2A GJA5 FBN1 PLEC NOTCH1 HSPG2 CAD FUZ TGFB2 TGFBR1 SETDB2 EGFR CTCF LRP2 RNF207 ADAP2

4.42e-0475723520GO:0007507
GeneOntologyBiologicalProcessregulation of cardiac epithelial to mesenchymal transition

NOTCH1 TGFB2 TGFBR1

4.84e-04142353GO:0062042
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2 LTBP4 FBN3

1.12e-05132404GO:0001527
GeneOntologyCellularComponentextracellular matrix

LAMC3 CHI3L1 SSPOP FBLN1 FBN1 FBN2 USH2A LTBP4 HSPG2 ADAMTS4 LAMB2 APOH ADAMTSL3 ADAMTS12 TGFB2 SNED1 ELFN1 FGFBP3 FBN3

2.19e-0465624019GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMC3 CHI3L1 SSPOP FBLN1 FBN1 FBN2 USH2A LTBP4 HSPG2 ADAMTS4 LAMB2 APOH ADAMTSL3 ADAMTS12 TGFB2 SNED1 ELFN1 FGFBP3 FBN3

2.27e-0465824019GO:0030312
MousePhenoabnormal thoracic aorta morphology

PCSK5 IFT140 GJA5 FBLN1 FBN1 HSPG2 FUZ TGFB2 TGFBR1 LRP2

6.65e-0613417410MP:0010468
MousePhenoabnormal aorta morphology

PCSK5 IFT140 GJA5 FBLN1 FBN1 LTBP4 HSPG2 FUZ TGFB2 TGFBR1 EGFR LRP2

2.49e-0522517412MP:0000272
DomainGrowth_fac_rcpt_

PCSK5 DNER LAMC3 LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 EGFR SLIT1 LRP2 FBN3

1.13e-1115623317IPR009030
DomainEGF_Ca-bd_CS

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 SNED1 SLIT1 LRP2 FBN3 CRB2

1.67e-119723314IPR018097
DomainEGF_CA

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 SNED1 SLIT1 LRP2 FBN3 CRB2

2.22e-119923314PS01187
DomainEGF_CA

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 SNED1 SLIT1 LRP2 FBN3 CRB2

3.32e-1112223315SM00179
DomainhEGF

DNER FBN2 NOTCH1 NOTCH3 NOTCH4 SNED1 SLIT1 FBN3 CRB2

3.52e-11282339PF12661
DomainEGF-like_Ca-bd_dom

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 SNED1 SLIT1 LRP2 FBN3 CRB2

4.20e-1112423315IPR001881
DomainEGF-type_Asp/Asn_hydroxyl_site

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 SNED1 SLIT1 LRP2 FBN3 CRB2

5.73e-1110623314IPR000152
DomainEGF_1

DNER LAMC3 SSPOP LRP1B ITGB7 FBLN1 FBN1 FBN2 USH2A LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 SNED1 SLIT1 LRP2 FBN3 CRB2

7.15e-1125523320PS00022
DomainZnf_RING

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A RNF141 NFX1 MARCHF1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 DPF3 RNF207 RFPL3

1.44e-1032623322IPR001841
DomainRING

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A RNF141 NFX1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 DPF3 RNF207 RFPL3

2.66e-1030523321SM00184
DomainASX_HYDROXYL

DNER LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 SNED1 LRP2 FBN3 CRB2

3.46e-1010023313PS00010
Domainzf-C3HC4

TRAF6 TRIM61 BFAR TRIM6 TRIM22 RNF141 NFX1 MARCHF1 TRIM15 RAPSN MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RNF207 RFPL3

4.15e-1022323318PF00097
DomainZF_RING_1

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A RNF141 NFX1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RNF207 RFPL3

7.44e-1029123320PS00518
DomainEGF

PCSK5 DNER LAMC3 LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 SNED1 SLIT1 LRP2 FBN3 CRB2

9.69e-1023523318SM00181
DomainEGF_2

DNER LAMC3 SSPOP LRP1B ITGB7 FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 SNED1 SLIT1 LRP2 FBN3 CRB2

9.94e-1026523319PS01186
DomainZF_RING_2

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A RNF141 NFX1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RNF207 RFPL3

1.13e-0929823320PS50089
Domain-

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A PIAS3 RNF141 PRPF19 MARCHF1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 DPF3 RNF207 RFPL3 RUFY4

2.28e-09449233243.30.40.10
DomainEGF-like_dom

PCSK5 DNER LAMC3 LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 SNED1 SLIT1 LRP2 FBN3 CRB2

2.45e-0924923318IPR000742
DomainZnf_RING/FYVE/PHD

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A PIAS3 RNF141 PRPF19 MARCHF1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 DPF3 RNF207 RFPL3 RUFY4

3.52e-0945923324IPR013083
DomainEGF-like_CS

DNER LAMC3 LRP1B ITGB7 FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 LAMB2 SNED1 SLIT1 LRP2 FBN3 CRB2

5.15e-0926123318IPR013032
DomainEGF_3

DNER SSPOP LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 HSPG2 SNED1 SLIT1 LRP2 FBN3 CRB2

4.50e-0823523316PS50026
DomainEGF_CA

LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 NOTCH4 LRP2 FBN3

1.16e-078623310PF07645
DomainZnf_RING_CS

NHLRC1 TRAF6 TRIM61 BFAR TRIM6 TRIM22 RNF141 TRIM15 TRIM5 RBCK1 RNF151 TRIM32 RNF207

1.37e-0716323313IPR017907
DomainEGF

DNER LRP1B NOTCH1 NOTCH3 NOTCH4 HSPG2 SNED1 SLIT1 LRP2 FBN3 CRB2

5.19e-0712623311PF00008
DomaincEGF

LRP1B FBLN1 FBN1 FBN2 LRP2 FBN3

6.60e-07262336PF12662
DomaincEGF

LRP1B FBLN1 FBN1 FBN2 LRP2 FBN3

6.60e-07262336IPR026823
DomainTB

FBN1 FBN2 LTBP4 FBN3

8.02e-0772334PF00683
Domain-

FBN1 FBN2 LTBP4 FBN3

1.59e-06823343.90.290.10
DomainZnf_C3HC4_RING-type

TRAF6 TRIM61 BFAR TRIM6 TRIM22 RNF141 MARCHF1 TRIM15 TRIM5 RBCK1 TRIM32 RNF207

1.75e-0617223312IPR018957
DomainFBN

FBN1 FBN2 FBN3

1.92e-0632333IPR011398
DomainTB_dom

FBN1 FBN2 LTBP4 FBN3

2.83e-0692334IPR017878
DomainTB

FBN1 FBN2 LTBP4 FBN3

2.83e-0692334PS51364
DomainZF_BBOX

TRIM61 TRIM6 TRIM22 TRIM15 TRIM5 RBCK1 TRIM32 RNF207

6.96e-06802338PS50119
DomainNotch

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333IPR008297
DomainNODP

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333IPR010660
DomainNOD

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333PF06816
DomainNOD

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333SM01338
DomainNODP

NOTCH1 NOTCH3 NOTCH4

7.60e-0642333SM01339
DomainZnf_B-box

TRIM61 TRIM6 TRIM22 TRIM15 TRIM5 RBCK1 TRIM32 RNF207

7.64e-06812338IPR000315
DomainLNR

NOTCH1 NOTCH3 NOTCH4

1.88e-0552333PS50258
DomainLdl_recept_a

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

1.92e-05452336PF00057
Domain-

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

2.18e-054623364.10.400.10
DomainLDLRA_1

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

2.80e-05482336PS01209
DomainLDrepeatLR_classA_rpt

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

3.16e-05492336IPR002172
DomainLDLa

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

3.16e-05492336SM00192
DomainLDLRA_2

LDLRAD1 SSPOP LRP1B HSPG2 LRP2 CORIN

3.16e-05492336PS50068
Domainzf-RING_UBOX

TRIM6 TRIM22 TRIM5 RBCK1 TRIM32

6.00e-05342335PF13445
DomainZnf-RING_LisH

TRIM6 TRIM22 TRIM5 RBCK1 TRIM32

6.00e-05342335IPR027370
DomainNotch_dom

NOTCH1 NOTCH3 NOTCH4

6.46e-0572333IPR000800
DomainNotch

NOTCH1 NOTCH3 NOTCH4

6.46e-0572333PF00066
DomainNL

NOTCH1 NOTCH3 NOTCH4

6.46e-0572333SM00004
DomainEGF_extracell

DNER LRP1B ITGB7 NOTCH1 NOTCH3 LRP2

1.01e-04602336IPR013111
DomainEGF_2

DNER LRP1B ITGB7 NOTCH1 NOTCH3 LRP2

1.01e-04602336PF07974
DomainLDLR_class-A_CS

SSPOP LRP1B HSPG2 LRP2 CORIN

1.33e-04402335IPR023415
DomainNACHT

NLRP11 CIITA NLRC5 NLRP14

1.73e-04232334PS50837
DomainNACHT_NTPase

NLRP11 CIITA NLRC5 NLRP14

1.73e-04232334IPR007111
DomainNHL_repeat

NHLRC1 LRP1B TRIM32

2.16e-04102333IPR001258
DomainNHL

NHLRC1 LRP1B TRIM32

2.16e-04102333PF01436
DomainButyrophylin

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

2.38e-04702336IPR003879
Domain6-blade_b-propeller_TolB-like

NHLRC1 LRP1B TECPR2 TRIM32 LRP2

2.62e-04462335IPR011042
Domainzf-B_box

TRIM61 TRIM6 TRIM22 TRIM15 TRIM5 RNF207

2.78e-04722336PF00643
DomainFol_N

DNER SNED1 SLIT1

2.94e-04112333IPR003645
DomainFOLN

DNER SNED1 SLIT1

2.94e-04112333SM00274
DomainConA-like_dom

TRIM6 TRIM22 USH2A HSPG2 TRIM15 RFPL1 TRIM5 SLIT1 RFPL3 CRB2

4.42e-0421923310IPR013320
DomainDUF3454

NOTCH1 NOTCH3

4.61e-0432332PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

4.61e-0432332IPR024600
DomainDUF3454

NOTCH1 NOTCH3

4.61e-0432332SM01334
DomainEGF_LAM_2

LAMC3 USH2A HSPG2 LAMB2

5.01e-04302334PS50027
DomainEGF_LAM_1

LAMC3 USH2A HSPG2 LAMB2

5.01e-04302334PS01248
DomainLRR_6

NLRP11 CIITA NLRC5 FBXL15 NLRP14

6.06e-04552335PF13516
DomainSPRY

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

7.69e-04872336SM00449
DomainEGF_Lam

LAMC3 USH2A HSPG2 LAMB2

9.12e-04352334SM00180
DomainLaminin_EGF

LAMC3 USH2A HSPG2 LAMB2

9.12e-04352334PF00053
DomainLaminin_N

LAMC3 USH2A LAMB2

9.52e-04162333IPR008211
DomainLamNT

LAMC3 USH2A LAMB2

9.52e-04162333SM00136
DomainLAMININ_NTER

LAMC3 USH2A LAMB2

9.52e-04162333PS51117
DomainLaminin_N

LAMC3 USH2A LAMB2

9.52e-04162333PF00055
DomainTSP_1

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

1.13e-03632335PF00090
DomainSPRY

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

1.15e-03942336PF00622
DomainSPRY_dom

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

1.15e-03942336IPR003877
DomainB30.2/SPRY

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

1.22e-03952336IPR001870
DomainB302_SPRY

TRIM6 TRIM22 TRIM15 RFPL1 TRIM5 RFPL3

1.22e-03952336PS50188
DomainLAM_G_DOMAIN

USH2A HSPG2 SLIT1 CRB2

1.25e-03382334PS50025
DomainLaminin_EGF

LAMC3 USH2A HSPG2 LAMB2

1.25e-03382334IPR002049
DomainTSP1

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

1.30e-03652335SM00209
DomainTSP1_rpt

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

1.30e-03652335IPR000884
DomainTSP1

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

1.30e-03652335PS50092
Domain-

NHLRC1 LRP1B TRIM32 LRP2

1.38e-033923342.120.10.30
DomainRDM_domain_RFPL

RFPL1 RFPL3

1.51e-0352332IPR022723
DomainRDM

RFPL1 RFPL3

1.51e-0352332PF11002
DomainLaminin_G_2

USH2A HSPG2 SLIT1 CRB2

1.52e-03402334PF02210
DomainPLAC

PCSK5 ADAMTSL3 ADAMTS12

1.60e-03192333PS50900
DomainPLAC

PCSK5 ADAMTSL3 ADAMTS12

1.60e-03192333IPR010909
DomainBBOX

TRIM6 TRIM22 TRIM15 TRIM5 TRIM32

1.70e-03692335SM00336
DomainCadherin_C

PCDHB5 PCDHB14 PCDHB13 PCDHB8

1.82e-03422334IPR032455
DomainCadherin_C_2

PCDHB5 PCDHB14 PCDHB13 PCDHB8

1.82e-03422334PF16492
Domain-

TRIM61 TRIM6 TRIM22 TRIM15 TRIM5

1.93e-037123354.10.45.10
DomainLamG

USH2A HSPG2 SLIT1 CRB2

2.17e-03442334SM00282
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP SEMA5B NOTCH1 NOTCH3 NOTCH4 ADAMTS4 ADAMTSL3 ADAMTS12

8.31e-07681578M27303
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBLN1 FBN1 FBN2 LTBP4 TGFB2 FBN3

3.03e-06371576M27134
PathwayREACTOME_SIGNALING_BY_NOTCH

KAT2A NOTCH1 NOTCH3 NOTCH4 ITCH EGFR

4.18e-06391576MM14604
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBLN1 FBN1 FBN2 LTBP4 TGFB2 FBN3

8.63e-06441576M26969
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NFX1 NOTCH1 NOTCH3 NOTCH4

9.79e-06131574M47534
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH3 NOTCH4

1.33e-0551573M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

1.33e-0551573MM14733
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH3 NOTCH4

2.64e-0561573M27068
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

SSPOP SEMA5B NOTCH1 NOTCH3 NOTCH4 HSPG2 ADAMTS4 ADAMTSL3 ADAMTS12

3.13e-051431579M27275
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3 NOTCH4

4.59e-0571573MM14734
PathwayPID_NOTCH_PATHWAY

DNER SSPOP NOTCH1 NOTCH3 NOTCH4 ITCH

4.80e-05591576M17
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH3 NOTCH4 TGFB2 TGFBR1

5.25e-05371575M39506
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

6.82e-05391575M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

6.82e-05391575MM15165
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP4 TGFB2

7.28e-0581573M47850
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

KAT2A NOTCH1 NOTCH3 NOTCH4

1.11e-04231574MM14954
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH3 NOTCH4 EGFR

1.32e-04241574M11190
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMC3 ITGB7 FBLN1 FBN1 FBN2 PLEC LTBP4 HSPG2 ADAMTS4 LAMB2 TGFB2 FBN3

1.35e-0430015712M610
PathwayKEGG_LEISHMANIA_INFECTION

TRAF6 TAB2 NCF2 JAK1 NFKBIA TGFB2

1.48e-04721576M3126
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2 TGFBR1 FBN3

1.56e-04251574M39713
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH3 NOTCH4

2.09e-04111573M47865
PathwayKEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY

TRAF6 TAB2 NFKBIA

2.09e-04111573M47493
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DNER NOTCH1 NOTCH3 NOTCH4

2.13e-04271574M39545
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

KAT2A NOTCH1 NOTCH3 NOTCH4

2.46e-04281574M6177
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH3 NOTCH4

2.77e-04121573M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH3 NOTCH4

2.77e-04121573M47533
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NFKBIA NOTCH1 NOTCH3 NOTCH4 ITCH EGFR

3.02e-04821576MM15922
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH3 NOTCH4

3.57e-04131573M47423
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP4 TGFB2

4.18e-04321574MM14854
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_INTERFERON_INDUCTION

TRAF6 STAT2 JAK1 NFKBIA

4.71e-04331574M39909
PathwayREACTOME_DISEASES_OF_METABOLISM

NHLRC1 SSPOP SEMA5B NOTCH1 NOTCH3 NOTCH4 HSPG2 ADAMTS4 ADAMTSL3 ADAMTS12

4.92e-0425015710M27554
PathwayWP_CANCER_PATHWAYS

TRAF6 LAMC3 ADCY1 ADCY3 STAT2 JAK1 NFKBIA NOTCH1 NOTCH3 NOTCH4 NTRK1 LAMB2 TGFB2 TGFBR1 EGFR

5.41e-0450715715M48302
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

ADCY1 ADCY3 UCP1 DPF3

5.92e-04351574M47969
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 LTBP4 TGFB2 TGFBR1

8.14e-04381574MM14874
PathwayPID_INTEGRIN5_PATHWAY

ITGB7 FBN1 TGFBR1

8.22e-04171573M212
PathwayKEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY

TRAF6 TAB2 NFKBIA

8.22e-04171573M47912
PathwayREACTOME_TAK1_DEPENDENT_IKK_AND_NF_KAPPA_B_ACTIVATION

TRAF6 TAB2 NFKBIA NLRC5

8.99e-04391574MM15116
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP4 TGFB2

8.99e-04391574MM14601
PathwayREACTOME_SIGNALING_BY_NOTCH1

KAT2A NOTCH1 ITCH

9.78e-04181573MM14775
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

9.78e-04181573M614
PathwayKEGG_PATHWAYS_IN_CANCER

STK36 TRAF6 LAMC3 JAK1 PIAS3 NFKBIA NTRK1 LAMB2 TGFB2 TGFBR1 EGFR

1.04e-0332515711M12868
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_TIR_TO_TLR2_4_MAPK_SIGNALING_PATHWAY

TRAF6 TAB2

1.21e-0351572M49008
PathwayWP_TCA_CYCLE_NUTRIENT_USE_AND_INVASIVENESS_OF_OVARIAN_CANCER

JAK1 EGFR

1.21e-0351572M39621
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

KAT2A NOTCH1 NOTCH4

1.34e-03201573M27881
PathwayKEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY

TRAF6 TAB2 NFKBIA

1.34e-03201573M47563
PathwayREACTOME_O_LINKED_GLYCOSYLATION

B3GNT4 SSPOP SEMA5B ADAMTS4 ADAMTSL3 ADAMTS12

1.37e-031091576MM15164
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCSK5 STK36 PIEZO1 DGKQ LAMC3 KAT2A PLEKHM1 MDN1 TMEM132A NFX1 NLRC5 PLEC LTBP4 NOTCH1 PKN3 SEMA6C HSPG2 MEX3D NTSR1 LAMB2 CEP192 CACFD1 ARHGEF40 MROH6 HPS6 FLCN ESPL1

3.34e-0811052492735748872
Pubmed

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

TRAF6 TRIM22 KLHL23 DCAF4L1 KLHL6 DCAF15 TRIM15 ITCH ZBTB8A TRIM32

6.55e-081382491028786561
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

NHLRC1 STAT2 JAK1 FBXL18 KLHL23 PRPF19 KLHL6 RAPSN NTRK1 FBXL15 DNAAF9 KLHL38 FBH1 EGFR TRIM32

9.41e-083722491522939624
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3 NOTCH4

3.63e-073249325846406
Pubmed

TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation.

TRAF6 TAB2 TRIM22

3.63e-073249323818111
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRAF6 VPS45 MBD1 PEG3 DNER MYNN LRP1B FAM53C JAK1 FBN1 PIAS3 HPS4 PLEC MGAT5B DOP1B BRWD1 ITCH FUZ CTDSP1 DNAAF9 WDR26 TRIM5 RBCK1 FBH1 TRIM32 LRP2 ZNF565

6.61e-0712852492735914814
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249328669409
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2 FBN3

1.44e-064249325034023
Pubmed

TRIM22 inhibits respiratory syncytial virus replication by targeting JAK-STAT1/2 signaling.

TRIM22 STAT2 JAK1

1.44e-064249332803897
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249311401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH3 NOTCH4

1.44e-06424938898100
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249317920003
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249328061457
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249324151014
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2 TGFBR1

1.44e-064249316835936
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3C RIMBP3 RIMBP3B

1.44e-064249319091768
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249318184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249315917835
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249319404845
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249323444212
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2 LTBP4

1.44e-064249312429738
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249310194420
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH3 NOTCH4

1.44e-064249311459941
Pubmed

Protocadherins.

PCDHB5 PCDHB14 PCDHB13 PCDHB8

1.74e-0613249412231349
Pubmed

Heritable Thoracic Aortic Disease Overview

FBN1 FBN2 NOTCH1 TGFB2 TGFBR1

2.22e-0630249520301299
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3C RIMBP3 RNF151 RIMBP3B

2.43e-0614249417662146
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH3 NOTCH4

3.59e-065249321124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH3 NOTCH4

3.59e-065249323675950
Pubmed

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

TRAF6 NOTCH1 TGFBR1

3.59e-065249324399296
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH3 NOTCH4

3.59e-065249311101851
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

FBN1 FBN2 HSPG2

3.59e-065249323493297
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 NOTCH3 NOTCH4

3.59e-065249320554499
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3C RIMBP3 RIMBP3B

3.59e-065249317855024
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH3 NOTCH4

3.59e-065249315882997
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH3 NOTCH4

7.14e-06624939111338
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249312244553
Pubmed

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

NOTCH1 NOTCH3 NOTCH4

7.14e-06624937835890
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249318299578
Pubmed

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6.

TRAF6 TAB2 NFKBIA

7.14e-066249311809792
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249320870902
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249317822320
Pubmed

Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.

TRAF6 NOTCH1 NOTCH4

7.14e-066249329228365
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249321991352
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249322615412
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH3 NOTCH4

7.14e-066249319503073
Pubmed

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.

TRIM22 TRIM15 TRIM5 TRIM32

7.25e-0618249423077300
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

JAK1 NOTCH1 NOTCH3 NOTCH4 GDF3 TGFB2 TGFBR1

8.05e-06100249724859004
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

FBLN1 FBN1 LTBP4 HSPG2 LAMB2 APOH FRZB

8.60e-06101249720551380
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1B ITGB7 NOTCH1 NOTCH3 NTRK1 EGFR LRP2

8.60e-06101249723382219
Pubmed

The tripartite motif family identifies cell compartments.

TRIM6 TRIM22 TRIM15 TRIM5 TRIM32

1.10e-0541249511331580
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB5 PCDHB14 PCDHB13 PCDHB8

1.14e-0520249411322959
Pubmed

A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.

NOTCH1 NOTCH4 TGFB2 TGFBR1

1.14e-0520249412588999
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH3 NOTCH4

1.24e-057249310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH3 NOTCH4

1.24e-057249312846471
Pubmed

Unique features of TRIM5alpha among closely related human TRIM family members.

TRIM6 TRIM22 TRIM5

1.24e-057249317156811
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH3 NOTCH4

1.24e-057249311518718
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH3 NOTCH4

1.98e-058249312242716
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH3 NOTCH4

1.98e-05824939858718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH3 NOTCH4

1.98e-058249322156581
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

NOTCH1 NOTCH3 NOTCH4 TGFB2

2.04e-0523249414701881
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

PCSK5 FBLN1 FBN1 LTBP4 NOTCH1 HSPG2 LAMB2

2.38e-05118249721078624
Pubmed

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

GJA5 NOTCH1 NOTCH3 NOTCH4 TGFBR1

2.41e-0548249528924218
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

FBN1 FBN2 HSPG2 ADAMTS4 FGFBP3

2.94e-0550249523658023
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBLN1 FBN1 FBN2

2.95e-059249312122015
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH3 NOTCH4

2.95e-059249311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH3 NOTCH4

2.95e-059249316245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH3 NOTCH4

2.95e-059249312370315
Pubmed

RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.

TRAF6 TAB2 RBCK1

2.95e-059249317449468
Pubmed

HIV-1 gp120 activates the STAT3/interleukin-6 axis in primary human monocyte-derived dendritic cells.

STAT2 PIAS3 NFKBIA

2.95e-059249325008924
Pubmed

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO.

TAB2 NFKBIA RBCK1

2.95e-059249321811235
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

FBN1 NOTCH4 TGFB2 TGFBR1

3.95e-0527249435894043
Pubmed

SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.

NOTCH1 NOTCH4 TGFB2 TGFBR1

3.95e-0527249433227706
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH3 NOTCH4

4.19e-0510249323665443
Pubmed

TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40.

TRAF6 TAB2 NFKBIA

4.19e-0510249315670770
Pubmed

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.

NOTCH1 NOTCH3 NOTCH4

4.19e-0510249314766969
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH3 NOTCH4

4.19e-0510249333915108
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PEG3 ADCY3 NCDN STARD9 ZFR2 RAB3GAP2 ARHGEF9 DOP1B CNKSR2 HEATR5A CEP192 SLIT1

4.23e-054072491212693553
Pubmed

Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins.

ADAP1 ADAP2

5.11e-052249214690521
Pubmed

Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.

NOTCH1 NOTCH4

5.11e-052249224305720
Pubmed

Defective formation of the inner limiting membrane in laminin beta2- and gamma3-null mice produces retinal dysplasia.

LAMC3 LAMB2

5.11e-052249219907020
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

5.11e-052249230044367
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

5.11e-052249215131124
Pubmed

Notch signaling in cancer.

NOTCH1 NOTCH4

5.11e-052249212496471
Pubmed

beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.

APOH LRP2

5.11e-05224929727058
Pubmed

Knockdown of Tripartite motif-containing 22 (TRIM22)relieved the apoptosis of lens epithelial cells by suppressing the expression of TNF receptor-associated factor 6 (TRAF6).

TRAF6 TRIM22

5.11e-052249234558381
Pubmed

Relationship of TRIM5 and TRIM22 polymorphisms with liver disease and HCV clearance after antiviral therapy in HIV/HCV coinfected patients.

TRIM22 TRIM5

5.11e-052249227590274
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

5.11e-052249220404337
Pubmed

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming.

TGFB2 EGFR

5.11e-052249227852038
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

5.11e-05224928791520
Pubmed

Gastrin-releasing peptide receptor in breast cancer mediates cellular migration and interleukin-8 expression.

GRPR EGFR

5.11e-052249219631337
Pubmed

Notch signaling: from the outside in.

NOTCH1 NOTCH4

5.11e-052249211112321
Pubmed

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.

NOTCH3 NOTCH4

5.11e-052249217696940
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

5.11e-05224927744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

5.11e-052249226408953
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

5.11e-052249218006876
Pubmed

[Cross-talk between Notch1 and epidermal growth factor receptor signalling in regulating cell proliferation of human tongue squamous carcinoma cells].

NOTCH1 EGFR

5.11e-052249220193370
InteractionNTN5 interactions

LRP1B FBN1 FBN2 LTBP4 NOTCH1 NOTCH3 LRP2

7.17e-09242327int:NTN5
InteractionCCN2 interactions

FBLN1 MEX3A KLHL23 HSPG2 TGFB2 EGFR LRP2

3.30e-07402327int:CCN2
InteractionIGFL3 interactions

PCSK5 LRP1B FBLN1 FBN2 NOTCH1 NOTCH3 LAMB2 LRP2

2.38e-06752328int:IGFL3
InteractionZFP41 interactions

LRP1B FBLN1 FBN1 FBN2 LTBP4 NOTCH3 LRP2

3.97e-06572327int:ZFP41
InteractionFBXO2 interactions

PCSK5 PIEZO1 CD109 LAMC3 LRP1B FBN1 FBN2 IL17RA ADGRF1 LTBP4 NOTCH1 NOTCH3 HSPG2 LAMB2 SNED1 EGFR LRP2

6.06e-0641123217int:FBXO2
InteractionHSP90AA1 interactions

NHLRC1 STK36 TRAF6 TAB2 BCL6 STAT2 MEN1 JAK1 MEX3A FBXL18 SYDE2 KLHL23 PRPF19 PRR14L PKN3 BRWD1 KLHL6 HSPG2 CAD RAPSN NTRK1 FBXL15 YTHDC2 SPG11 HEATR5A DNAAF9 RBCK1 KLHL38 TGFBR1 FBH1 EGFR TRIM32 FLCN

8.75e-06126323233int:HSP90AA1
InteractionTRIM22 interactions

TAB2 KAT2A TRIM22 CIITA NFKBIA

1.84e-05292325int:TRIM22
InteractionMAP3K7 interactions

TRAF6 TAB2 KAT2A PLEKHM1 NFKBIA NFX1 IL17RA NOTCH4 ITCH RNF19A TRIM5 RBCK1 PLEKHG4B TGFBR1 EGFR

3.70e-0538023215int:MAP3K7
InteractionPCDHB3 interactions

B3GNT4 PCDHB5 ADCY3 TMEM132A ADGRF1 NTRK1 PCDHB13 PCDHB8 EGFR

3.81e-051412329int:PCDHB3
InteractionNOTCH3 interactions

MBD1 FBLN1 CPNE6 MARCHF1 NOTCH1 NOTCH3 NOTCH4 NTRK1

4.95e-051132328int:NOTCH3
Cytoband2q35

STK36 ZFAND2B CTDSP1 RUFY4 DNPEP

7.47e-057925052q35
CytobandEnsembl 112 genes in cytogenetic band chr7p22

AMZ1 FBXL18 ADAP1 ZDHHC4 ELFN1 WIPI2

9.85e-051342506chr7p22
Cytoband11p15.4

TRIM6 RNF141 DNHD1 MRGPRE RRP8 OR52P1 NLRP14

1.22e-04200250711p15.4
Cytoband5q31

PCDHB5 FAM53C PCDHB14 PCDHB13 PCDHB8

4.34e-0411525055q31
CytobandEnsembl 112 genes in cytogenetic band chr2q35

STK36 ZFAND2B CTDSP1 RUFY4 DNPEP

7.31e-041292505chr2q35
Cytoband7p22.3

AMZ1 ADAP1 ELFN1

8.43e-043425037p22.3
CytobandEnsembl 112 genes in cytogenetic band chr11p15

TRIM6 TRIM22 RNF141 DNHD1 MRGPRE RRP8 TSPAN32 OR52P1 TRIM5 NLRP14

1.15e-0356425010chr11p15
GeneFamilyRing finger proteins

TRAF6 TRIM61 BFAR TRIM6 TRIM22 MEX3A RNF141 MARCHF1 TRIM15 RAPSN RNF19A MEX3D RFPL1 TRIM5 RBCK1 RNF151 TRIM32 RNF207

2.80e-102751791858
GeneFamilyNLR family

NLRP11 CIITA NLRC5 NLRP14

9.99e-05251794666
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM61 TRIM6 TRIM22 TRIM15 TRIM5 TRIM32

3.63e-0495179659
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

PEG3 ZNF205 ZNF683 MYNN BCL6 ZNF474 ZBTB8A ZNF784 ZNF414 ZSCAN10 KLF1 CTCF ZFHX2 ZNF565 ZNF281 ZNF513 ZNF646

7.99e-047181791728
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMC3 SSPOP FBLN1 FBN1 FBN2 USH2A LTBP4 LAMB2 LGI4 SNED1 SLIT1 FBN3

3.55e-0719624512M3008
CoexpressionNABA_CORE_MATRISOME

LAMC3 SSPOP FBLN1 FBN1 FBN2 USH2A LTBP4 HSPG2 LAMB2 LGI4 SNED1 SLIT1 FBN3

2.15e-0627524513M5884
CoexpressionNABA_MATRISOME

PCSK5 CD109 LAMC3 SSPOP FBLN1 FBN1 FBN2 SEMA5B USH2A LTBP4 SEMA6C HSPG2 ADAMTS4 LAMB2 ADAMTSL3 GDF3 LGI4 ADAMTS12 TGFB2 SNED1 ELFN1 FGFBP3 FRZB SLIT1 FBN3

1.31e-05102624525M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMC3 SSPOP FBLN1 FBN1 FBN2 LTBP4 LAMB2 LGI4 SNED1 SLIT1

1.36e-0519124510MM17059
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN

STK36 PIEZO1 MBD1 DGKQ DENND1C KAT2A TRIM22 PLEKHM1 STAT2 JAK1 CDAN1 HPS4 NLRC5 MARCHF1 LTBP4 NOTCH1 DOP1B ADAP1 CEP192 TSPAN32 TRIM5 RBCK1 ZNF513

1.53e-0590524523M40865
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GNMT FBN1 GSPT2 KLHL23 NOTCH3 ZBTB8A ZNF784 ADAMTSL3 TGFB2 AOC3

5.19e-0817324910a37f38478473290fe35aea8684befc3bf95b161f
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH4 HSPG2 GRPR EVA1C

1.19e-0718924910b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH4 HSPG2 GRPR EVA1C

1.25e-0719024910aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH4 HSPG2 GRPR EVA1C

1.31e-07191249104b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PCSK5 CD109 GJA5 LTBP4 PKN3 NOTCH4 UACA LAMB2 TGFB2

1.38e-0719224910c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PCSK5 CD109 GJA5 LTBP4 PKN3 NOTCH4 UACA LAMB2 TGFB2

1.38e-0719224910144503af50274eaed5cf6effa892c640eab28663
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY3 SEMA5B NOTCH3 ADAMTS4 UACA LAMB2 LGI4 TGFB2 FRZB ADAP2

1.75e-0719724910452be45f4aac8459dd860493171f5f715368d663
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 AOC3 ADAP2

2.01e-0720024910d70bad979299615fcba707ba21296020918705e6
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMC3 ADCY3 SEMA5B KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB AOC3

2.01e-0720024910c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 AOC3 ADAP2

2.01e-072002491038c21ec379005f688df33aea65237a063c476c2e
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LAMC3 ADCY3 SEMA5B KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB AOC3

2.01e-072002491078e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC3 ADCY3 SEMA5B KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB AOC3

2.01e-072002491043b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 GJA5 LTBP4 PKN3 UACA RNF19A PCDHB13 LAMB2 EVA1C

8.66e-071812499136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 GSPT2 KLHL23 NOTCH3 ZNF784 ADAMTSL3 TGFB2 AOC3 ADAP2

9.07e-071822499be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 GSPT2 KLHL23 NOTCH3 ZNF784 ADAMTSL3 TGFB2 AOC3 ADAP2

9.07e-07182249974dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

LAMC3 SEMA5B NOTCH3 ADAMTS4 UACA ADAMTSL3 LGI4 FRZB AOC3

9.49e-071832499a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

LAMC3 SEMA5B STARD9 KLHL23 NOTCH3 ADAMTSL3 LGI4 FRZB AOC3

1.19e-0618824994963382e54aac06bf5047c7d725393db70667ee7
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

LAMC3 ADCY3 SEMA5B KLHL23 NOTCH3 NOTCH4 ADAMTSL3 LGI4 ADAP2

1.24e-0618924999c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 DNER FBLN1 FBN1 LTBP4 HSPG2 NTRK1 LGI4 EGFR

1.24e-061892499f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 DNER FBLN1 FBN1 LTBP4 HSPG2 NTRK1 LGI4 EGFR

1.24e-061892499378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 CD109 GJA5 LTBP4 PKN3 NOTCH4 UACA LAMB2 TGFB2

1.30e-061902499cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 CD109 GJA5 LTBP4 PKN3 NOTCH4 UACA LAMB2 TGFB2

1.30e-0619024995bf3d0beee69879c95265d07fba023626a7cc808
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTS4 UACA ADAMTSL3 LGI4

1.30e-0619024994eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTS4 UACA ADAMTSL3 LGI4

1.30e-0619024997be4341e2909101d756f14031c21e705eb45e69a
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

LAMC3 ADCY3 FBN1 SEMA5B LTBP4 NOTCH3 ADAMTS4 ADAMTSL3 ADAMTS12

1.35e-06191249978c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC3 SEMA5B KLHL23 NOTCH3 BEGAIN CCRL2 ADAMTSL3 AOC3 ADAP2

1.41e-061922499430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 FBN1 PKN3 NOTCH4 HSPG2 UACA EVA1C SNED1

1.48e-0619324992e72309607902dabe3218888b22a77fe941f3570
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

LAMC3 ADCY3 KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB ADAP2

1.54e-0619424993892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 GJA5 FBN1 TMEM132A LTBP4 PKN3 NOTCH4 HSPG2 GRPR

1.75e-061972499ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PLEC LTBP4 PKN3 NOTCH4 HSPG2 UACA

1.82e-0619824995e781583908c4ee107d986904a646a7c6b8e3591
ToppCellTracheal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 SEMA5B NOTCH3 ADAMTS4 LGI4 ADAMTS12 FRZB AOC3

1.90e-061992499cefc3b50f65e95da850e4720c7b44bf584073491
ToppCellTracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 SEMA5B NOTCH3 ADAMTS4 LGI4 ADAMTS12 FRZB AOC3

1.90e-061992499aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PLEC LTBP4 PKN3 NOTCH4 HSPG2 UACA

1.90e-061992499a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCelldistal-mesenchymal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC3 FBLN1 KLHL23 LTBP4 NOTCH3 ADAMTSL3 LGI4 FRZB AOC3

1.98e-062002499b54137a4545690f51e154bb05964eaa650c3ca8e
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 CNKSR2 ADAMTSL3 LGI4 AOC3

1.98e-0620024990c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 CNKSR2 ADAMTSL3 LGI4 AOC3

1.98e-062002499522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PCSK5 CD109 GJA5 FBN1 LTBP4 LAMB2 GRPR TGFB2 ELFN1

1.98e-062002499ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 CNKSR2 ADAMTSL3 LGI4 AOC3

1.98e-06200249994f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB AOC3

1.98e-062002499f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC3 FBLN1 KLHL23 LTBP4 NOTCH3 ADAMTSL3 LGI4 FRZB AOC3

1.98e-0620024994f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC3 ADCY3 KLHL23 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 FRZB AOC3

1.98e-0620024990a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC3 FBLN1 KLHL23 LTBP4 NOTCH3 ADAMTSL3 LGI4 FRZB AOC3

1.98e-062002499a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCellcellseq-Mesenchymal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC3 FBLN1 FBN1 KLHL23 LTBP4 NOTCH3 LGI4 FRZB AOC3

1.98e-062002499238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PLEC LTBP4 PKN3 NOTCH4 HSPG2 UACA

1.98e-06200249993e13937ec74418a697c37d56f57509fb2154780
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

TRIM61 KLHL23 NOTCH3 RAPSN CCRL2 ADAMTSL3 AOC3 ADAP2

2.21e-0615124983f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 LTBP4 NOTCH1 NOTCH4 UACA CCRL2 DPF3

3.90e-0616324981feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FBLN1 FBN1 LTBP4 CNKSR2 ADAMTSL3 ADAMTS12 FRZB SLIT1

7.78e-06179249810fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC3 ADCY3 STARD9 NOTCH3 ADAMTS4 ADAMTSL3 LGI4 AOC3

7.78e-061792498dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 SEMA5B KLHL23 NOTCH3 BEGAIN ADAMTS4 UACA AOC3

8.10e-06180249838035cf2c6fbc443ea10ca7e942572715ed572da
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PCDHB5 LAMC3 ADCY1 NOTCH3 ADAMTS4 ADAMTSL3 ADAMTS12 FRZB

8.43e-06181249835c470988a93381eefa300831aabb813fa1b90bd
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY3 CPNE6 FBN2 SEMA5B NOTCH3 ADAMTS12 AOC3 CORIN

9.14e-0618324984060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY3 CPNE6 FBN2 SEMA5B NOTCH3 ADAMTS12 AOC3 CORIN

9.14e-0618324980d44a978221cf3f733704bf11863502805fba733
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SSPOP LRP1B FBN2 USH2A CACNA1F CNKSR2 LRP2

9.51e-0618424982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SSPOP LRP1B FBN2 USH2A CACNA1F CNKSR2 LRP2

9.51e-0618424982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SSPOP LRP1B FBN2 USH2A CACNA1F CNKSR2 LRP2

9.51e-061842498ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

LAMC3 ADCY3 KLHL23 NOTCH3 ADAMTS4 UACA ADAMTSL3 LGI4

9.89e-0618524984905adaeeffd353e089578e5ea614437dbe794e6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC3 ADCY3 STARD9 NOTCH3 UACA ADAMTSL3 LGI4 AOC3

1.03e-051862498888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD109 SEMA5B NOTCH3 ADAMTS4 LGI4 FRZB AOC3 ADAP2

1.07e-051872498150023e6a50c9da461f2321074d2d5e96caafb06
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 GJA5 LTBP4 PKN3 NOTCH4 LAMB2 EVA1C FRZB

1.07e-05187249812129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTSL3 LGI4 AOC3

1.07e-051872498fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 GJA5 LTBP4 PKN3 NOTCH4 LAMB2 EVA1C FRZB

1.07e-05187249883930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ADCY1 SEMA5B KLHL23 NOTCH3 LGI4 ADAMTS12 FRZB SLIT1

1.07e-05187249835f25780d113f60bf4c13749013c09612ee4ff41
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMC3 ADCY3 STARD9 KLHL23 NOTCH3 ADAMTSL3 LGI4 AOC3

1.11e-051882498ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMEM88 ADCY1 GJA5 TMEM132A NOTCH1 NOTCH4 HSPG2 UACA

1.11e-051882498366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH3 NOTCH4 EVA1C

1.11e-051882498ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM88 CD109 GJA5 NOTCH1 PKN3 NOTCH4 HSPG2 UACA

1.16e-051892498db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 GJA5 FBN1 PKN3 NOTCH4 HSPG2 GRPR EVA1C

1.16e-051892498c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH4 HSPG2 EVA1C

1.16e-05189249812b6f1c3bf526b90e112374bf937701f645c5780
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PKN3 NOTCH4 HSPG2 UACA EVA1C

1.16e-0518924986463890d8dbee4bc198f91628a5f784970de786a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC3 SEMA5B KLHL23 NOTCH3 BEGAIN CCRL2 AOC3 ADAP2

1.20e-051902498106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 FBN1 PKN3 NOTCH4 HSPG2 EVA1C

1.25e-051912498b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LAMC3 GJA5 FBN1 LTBP4 PKN3 NOTCH4 RNF151

1.25e-051912498b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PCSK5 CD109 GJA5 LTBP4 NOTCH4 UACA TGFB2

1.30e-051922498c0498baa2556e1597c00df2e75efadeb14bd34ef
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNER FBLN1 FBN1 LTBP4 HSPG2 NTRK1 LGI4 EGFR

1.30e-051922498c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNER FBLN1 FBN1 LTBP4 HSPG2 NTRK1 LGI4 EGFR

1.30e-051922498f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PKN3 NOTCH4 HSPG2 UACA EVA1C

1.30e-05192249856b021c297a21dff357531f21e2464f85186106d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DNER LAMC3 GRPR EGFR ELFN1 DPF3 CALY FBN3

1.30e-051922498025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PCSK5 CD109 GJA5 LTBP4 NOTCH4 UACA TGFB2

1.30e-051922498cb906b10cad76e978c5c0b966215368ebef30e51
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 FBN1 LTBP4 PKN3 NOTCH4 HSPG2 EVA1C

1.34e-0519324980b328f725f6feba263783eaca60c142e80df90f3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PKN3 NOTCH4 HSPG2 UACA EVA1C

1.45e-0519524986bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM88 PCSK5 GJA5 PKN3 NOTCH4 HSPG2 UACA EVA1C

1.45e-051952498b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 FBN1 PKN3 NOTCH4 HSPG2 EVA1C SNED1

1.45e-05195249877e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PEG3 FBLN1 FBN1 LTBP4 HSPG2 LAMB2 SNED1 EGFR

1.45e-051952498c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMC3 GJA5 FBN1 NOTCH3 UACA ADAMTSL3 ADAMTS12 FRZB

1.50e-05196249844e2df1b61e3819eae7e482bef0a733afe852d67
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMC3 GJA5 FBN1 NOTCH3 UACA ADAMTSL3 ADAMTS12 FRZB

1.50e-051962498cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 GJA5 LTBP4 NOTCH1 PKN3 NOTCH4 HSPG2 UACA

1.50e-051962498a20a56d8997d6db2a10046c8801c619a379de83c
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP11 ADCY1 ZFR2 USH2A KIF25-AS1 MLANA PLEKHG4B SLIT1

1.50e-0519624984bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 ADCY3 STAT2 FBLN1 FBN1 LTBP4 ADAMTS12 SNED1

1.56e-051972498b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellILEUM-inflamed-(8)_Pericytes|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NOTCH3 ADAMTS4 LAMB2 LGI4 ADAMTS12 FRZB SLIT1 AOC3

1.56e-051972498e04ac8575f66d798ddf2fd6d55d397a163b40732
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 ADCY3 STAT2 FBLN1 FBN1 LTBP4 ADAMTS12 SNED1

1.56e-051972498c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DNER NCF2 BCL6 IL17RA MARCHF1 LAMB2 ARHGEF40 ADAP2

1.62e-051982498a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC3 FBLN1 FBN1 LTBP4 NOTCH3 ADAMTS4 LGI4 AOC3

1.68e-0519924984d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM88 CD109 GJA5 LTBP4 PKN3 NOTCH4 HSPG2 UACA

1.68e-051992498f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CD109 GJA5 PLEC LTBP4 PKN3 NOTCH4 UACA

1.68e-0519924989b02acae6325b0ac9642438a4431285ff396e5fe
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC3 FBLN1 FBN1 LTBP4 NOTCH3 ADAMTS4 LGI4 AOC3

1.68e-05199249893e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADCY1 FBLN1 FBN1 LTBP4 LAMB2 ADAMTSL3 ADAMTS12 EGFR

1.68e-05199249895d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM88 CD109 GJA5 LTBP4 PKN3 NOTCH4 HSPG2 UACA

1.68e-05199249833f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY1 ADCY3 SEMA5B NOTCH3 ADAMTS4 LGI4 FRZB AOC3

1.68e-05199249878a9b26215874a46a910a4b93a51fcac1a597618
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY3 FBN1 STARD9 LTBP4 CNKSR2 ADAMTSL3 ADAMTS12 SNED1

1.68e-0519924983835452e4848d7f7dd8651c17b746b271ef39688
ToppCellmetastatic_Brain-Fibroblasts|metastatic_Brain / Location, Cell class and cell subclass

LAMC3 FBLN1 FBN1 NOTCH3 ADAMTS4 UACA ADAMTS12 FRZB

1.68e-05199249863eb2106bb6e2e33d020628583536c8d96662c84
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2 FBN3

4.92e-0732343DOID:65 (implicated_via_orthology)
Diseasebrain cancer (implicated_via_orthology)

INSM1 NOTCH1 NOTCH3 L3MBTL1

5.02e-05262344DOID:1319 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

CHI3L1 NFKBIA LTBP4 NOTCH1 NOTCH3 EGFR

5.66e-05842346C0334588
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 NOTCH1 TGFB2 TGFBR1

6.32e-05532345C4707243
Diseasesexual dimorphism measurement

PCSK5 B3GNT4 FAM184B AMZ1 BCL6 ADCY3 FBN1 NLRC5 PLEC RAD51B ITCH RAPSN CTDSP1 OR2J1 CACFD1 APOH ADAMTSL3 ZNF414 TGFB2 ARHGEF40 SLIT1 ADAP2

7.75e-05110623422EFO_0021796
Diseasealcohol use disorder (implicated_via_orthology)

ZNF683 ADCY1 NOTCH1 NOTCH3 DRD5 RIOX1 EGFR DPF3

1.75e-041952348DOID:1574 (implicated_via_orthology)
DiseaseLoeys-Dietz syndrome (implicated_via_orthology)

TGFB2 TGFBR1

1.87e-0432342DOID:0050466 (implicated_via_orthology)
DiseaseFamilial aortopathy

FBN1 TGFBR1

1.87e-0432342cv:CN078214
Diseasenuclear protein MDM1 measurement

ZFAND2B TRIM5

3.72e-0442342EFO_0802822
DiseaseLoeys-Dietz syndrome

TGFB2 TGFBR1

3.72e-0442342cv:C2697932
DiseaseCongenital dyserythropoietic anemia, type II

CDAN1 KLF1

3.72e-0442342C1306589
DiseaseCongenital dyserythropoietic anemia, type I

CDAN1 KLF1

3.72e-0442342C0271933
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

3.72e-0442342DOID:0060249 (is_implicated_in)
Diseaseschizophrenia (is_implicated_in)

CHI3L1 HPS4 NOTCH4 NTRK1 NTSR1

3.96e-04782345DOID:5419 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

LRP1B JAK1 TGFB2 TGFBR1 EGFR FLCN

4.20e-041212346DOID:9256 (is_implicated_in)
DiseaseGlioblastoma

CHI3L1 LTBP4 NOTCH1 NOTCH3 EGFR

4.20e-04792345C0017636
DiseaseCongenital dyserythropoietic anemia

CDAN1 KLF1

6.16e-0452342C0002876
DiseaseLoeys-Dietz Aortic Aneurysm Syndrome

TGFB2 TGFBR1

6.16e-0452342C1836635
Diseaselevel of Phosphatidylcholine (18:0_22:6) in blood serum

GNMT RAPSN

6.16e-0452342OBA_2045097
DiseaseCongenital dyserythropoietic anemia, type III

CDAN1 KLF1

6.16e-0452342C0271934
DiseaseLoeys-Dietz Syndrome, Type 1a

TGFB2 TGFBR1

6.16e-0452342C4551955
Diseasemonocyte percentage of leukocytes

PIEZO1 NBPF4 BCL6 JAK1 FBXL18 CIITA IL17RA RAD51B SEMA6C RAPSN ADAMTS4 CCRL2 TSPAN32 WDR26 RUFY4

7.96e-0473123415EFO_0007989
DiseaseMyasthenic Syndromes, Congenital

PLEC RAPSN LAMB2

8.81e-04242343C0751882
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3 NOTCH4

8.81e-04242343C0887833
DiseaseCongenital dyserythropoietic anemia

CDAN1 KLF1

9.20e-0462342cv:C0002876
Diseaseprimary ciliary dyskinesia (is_implicated_in)

STK36 BRWD1

9.20e-0462342DOID:9562 (is_implicated_in)
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH3 NOTCH4 TGFBR1

1.25e-03592344C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH3 NOTCH4 TGFBR1

1.25e-03592344C0037286
DiseaseLoeys-Dietz Syndrome

TGFB2 TGFBR1

1.28e-0372342C2697932
DiseaseAortic Aneurysm, Thoracoabdominal

FBN1 TGFB2

1.28e-0372342C0340630
DiseaseHermansky-Pudlak syndrome (is_implicated_in)

HPS4 HPS6

1.28e-0372342DOID:3753 (is_implicated_in)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

1.28e-0372342DOID:3620 (implicated_via_orthology)
DiseaseAortic Aneurysm, Thoracic

FBN1 TGFB2

1.28e-0372342C0162872
DiseaseSacral agenesis

PCSK5 FUZ

1.28e-0372342C0344490
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

1.28e-0372342DOID:299 (implicated_via_orthology)
Diseaseulcerative colitis

AMZ1 ADCY3 CIITA NOTCH1 NOTCH4 TRIM15 CCRL2 SLIT1 DNPEP

1.51e-033352349EFO_0000729
Diseasearteriosclerosis (is_marker_for)

CHI3L1 NOTCH4 APOH

1.54e-03292343DOID:2349 (is_marker_for)
Diseaseprotein-tyrosine sulfotransferase 2 measurement

HPS4 RAPSN

1.70e-0382342EFO_0801971
Diseasetriacylglycerol 58:6 measurement

TRAF6 LRP1B

1.70e-0382342EFO_0010440
DiseaseGlioblastoma Multiforme

CHI3L1 LTBP4 NOTCH1 NOTCH3 EGFR

1.95e-031112345C1621958
DiseaseFEV/FEC ratio

PCSK5 AMZ1 DNER ADCY3 FBLN1 FBN1 NFKBIA LTBP4 KLHL6 RAD51B HSPG2 ITCH ZNF474 RNF19A CNKSR2 ADAMTSL3 GRPR TGFB2 CTCF CRB2

1.97e-03122823420EFO_0004713
DiseaseMuscular Dystrophies, Limb-Girdle

PLEC RAPSN TRIM32

2.06e-03322343C0686353
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH3 EGFR

2.06e-03322343DOID:10155 (implicated_via_orthology)
DiseasePR interval

LDLRAD1 BCL6 GJA5 FBN2 NFKBIA PLEC HSPG2 RAPSN LAMB2 KLHL38 ARHGEF40

2.13e-0349523411EFO_0004462
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

2.17e-0392342DOID:264 (is_marker_for)
Diseasehead and neck malignant neoplasia

LAMC3 TRIM5

2.17e-0392342EFO_0006859
DiseaseCancer of Nasopharynx

NFKBIA EGFR

2.17e-0392342C0238301
Diseaserheumatoid arthritis (is_marker_for)

TAB2 CHI3L1 NOTCH4 ADAMTS4

2.23e-03692344DOID:7148 (is_marker_for)
Diseasehypertension (biomarker_via_orthology)

NCF2 CHI3L1 GJA5 FBN1 NFKBIA HSPG2 EGFR

2.32e-032272347DOID:10763 (biomarker_via_orthology)
Diseasecervical cancer

PIAS3 NOTCH1 EGFR

2.46e-03342343C4048328
DiseaseUterine Cervical Neoplasm

PIAS3 NOTCH1 EGFR

2.67e-03352343C0007873
Diseaseendometrial cancer (is_marker_for)

CHI3L1 NOTCH1 NOTCH4

2.67e-03352343DOID:1380 (is_marker_for)
DiseaseHermanski-Pudlak Syndrome

HPS4 HPS6

2.70e-03102342C0079504
Diseaseaortic aneurysm

FBN1 TGFB2

2.70e-03102342EFO_0001666
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 TGFBR1

2.70e-03102342cv:C4707243
DiseaseHermansky-Pudlak syndrome

HPS4 HPS6

2.70e-03102342cv:C0079504
Diseasepentachlorophenol measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022071
Diseaseparathion measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022070
Diseasepotassium chromate measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022072
Diseasemercuric chloride measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022068
Diseaseheptachlor epoxide measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022067
Diseasemethoxychlor measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022069
Disease4,6-dinitro-o-cresol measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022053
Disease2,4,5-trichlorophenol measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022052
Diseaseazinphos methyl measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022055
Diseasealdrin measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022054
Diseasedicofol measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022060
Diseasedisulfoton measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022062
Diseasedieldrin measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022061
Diseaseendrin measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022064
Diseaseendosulfan measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022063
Diseaseheptachlor measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022066
Diseaseethion measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022065
Diseasechlorpyrifos measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022057
Diseasecadmium chloride measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022056
Diseasediazinon measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022059
Diseasedibutyl phthalate measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0022058
Diseaseenvironmental exposure measurement

DNER FRMD1 USH2A DPF3

2.73e-03732344EFO_0008360
DiseaseDDT metabolite measurement

DNER FRMD1 USH2A DPF3

2.87e-03742344EFO_0007886
Diseasesmoking behavior, BMI-adjusted waist circumference

PCSK5 AMZ1 ADAMTSL3 TGFB2 ADAP2

2.94e-031222345EFO_0004318, EFO_0007789
Diseasehematocrit

STK36 AMZ1 PIEZO1 BCL6 GJA5 FBLN1 C12orf76 LTBP4 NOTCH4 RAD51B RAPSN DUSP9 DNAAF9 ARHGEF40 KLF1 DPF3 LRP2

3.07e-03101123417EFO_0004348
Diseasefree cholesterol to total lipids in large VLDL percentage

NLRC5 RAPSN APOH

3.14e-03372343EFO_0022281
Diseaseinflammatory bowel disease

PCSK5 AMZ1 TAB2 KAT2A ADCY3 NOTCH1 NOTCH4 RAPSN CCRL2 DNPEP

3.30e-0344923410EFO_0003767
DiseaseLung diseases

PCSK5 HPS4 LTBP4 FLCN

3.48e-03782344C0024115
Diseaseeosinophil count

MYNN DCST2 BCL6 JAK1 MDN1 CIITA NFKBIA NLRC5 IL17RA PLEC LTBP4 NOTCH1 NOTCH4 RAD51B RAPSN ADAMTS4 UACA TSPAN32 APOH C9orf163 RBCK1 CD5

3.85e-03148823422EFO_0004842
DiseaseColorectal Carcinoma

PEG3 CD109 NCDN FBN2 C12orf76 PIGO CAD CNKSR2 ADAMTSL3 TGFBR1 EGFR LRP2 FLCN

4.22e-0370223413C0009402
DiseaseAPOE carrier status, cerebral amyloid angiopathy

DNER YTHDC2 EVA1C

4.50e-03422343EFO_0006790, EFO_0007659
Diseasehematologic cancer (implicated_via_orthology)

JAK1 PIAS3

4.61e-03132342DOID:2531 (implicated_via_orthology)
DiseaseConnective Tissue Diseases

NOTCH1 FLCN

4.61e-03132342C0009782
Diseasexanthine measurement

RAD51B CNKSR2

4.61e-03132342EFO_0010548
Diseaseintercellular adhesion molecule 5 measurement

S1PR2 RAVER1

4.61e-03132342EFO_0008164
Diseaselung non-small cell carcinoma (is_implicated_in)

NAT1 LRP1B JAK1 EGFR FRZB

5.11e-031392345DOID:3908 (is_implicated_in)
DiseaseThromboembolism

TRIM6 TRIM22 TRIM5

5.13e-03442343HP_0001907
DiseasePsychosis, Brief Reactive

DRD5 NTRK1

5.35e-03142342C0033958
DiseaseAutosomal recessive limb-girdle muscular dystrophy

PLEC TRIM32

5.35e-03142342cv:C2931907
DiseaseSchizophreniform Disorders

DRD5 NTRK1

5.35e-03142342C0036358
Diseaseresponse to radiation, hearing loss, response to antineoplastic agent

ADCY1 NFKBIA SCART1

5.81e-03462343EFO_0004238, GO_0009314, GO_0097327
DiseaseIGF-1 measurement

IFT140 INSM1 S1PR2 ADCY1 JAK1 STARD9 DOP1B RAPSN APOH SLIT1

5.86e-0348823410EFO_0004627
DiseaseHemoglobin F Disease

CAD KLF1

6.14e-03152342C0019025
Diseasehepatocellular carcinoma (implicated_via_orthology)

GNMT CAD UACA

6.94e-03492343DOID:684 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
SFCSLQTPDGVHCLV

NAT1

221

P18440
LCRCFHLRSNTPLQP

CCRL2

311

O00421
AGLRHNHTCLTICLP

ELFN1

386

P0C7U0
QGCATHPLRIGACFL

ARHGEF40

1146

Q8TER5
SFLCHVAIAGRTCPK

APOH

11

P02749
EPVGSSLLHQLCSCT

AMZ1

106

Q400G9
RICFPHSQECLSLPQ

ANTXRL

491

A6NF34
RSHTGERPFQCSLCS

CTCF

371

P49711
PRLDNLHSCFCALQA

DNPEP

271

Q9ULA0
DLSQGHLAEPCFLRA

BEGAIN

481

Q9BUH8
TAGALPSCECHLNNL

ADGRF1

126

Q5T601
DFVFSVPCHCLNRPG

CIITA

446

P33076
PICSANICLSGVRFL

C9orf163

96

Q8N9P6
GAISAHCNLCLPDLS

CCDC28A-AS1

66

A0A096LPI5
SCAISGLFNCITIHP

CACFD1

41

Q9UGQ2
TSRGLFCPHQKLSQC

CD5

336

P06127
HLFSQVPCFRVLVCG

DGKQ

631

P52824
CLSCSGIHRNIPQVS

ADAP1

41

O75689
HNLRGLLCALFPSAS

DNHD1

1926

Q96M86
RALSVGNCPRSHFQC

C1orf147

171

Q96MC9
SLNPLLCAFRCHNTE

FBN3

2171

Q75N90
SLRPSQSLDCCHRGD

DENND1C

576

Q8IV53
CHRGDLDSCFSLPNI

DENND1C

586

Q8IV53
EILCSQLCPHGAQAL

CDAN1

916

Q8IWY9
PNGSCRDFCLETEIH

DEFB108B

31

Q8NET1
NRVFFCHGELCIIPA

ECD

136

O95905
CAGFNRPCETLGLSH

ADAMTS12

351

P58397
LNCCGVHRNFPDISR

ADAP2

46

Q9NPF8
NGHLDPNSDCLCLGR

ARHGEF9

81

O43307
RELPQASGLLHHCCF

AOC3

186

Q16853
PRALCTQLACAHSEL

C17orf113

576

A0A1B0GUU1
PFRLSLHSLCSCDVH

CPNE6

206

O95741
PSCLRLQLDQGFHCG

NBPF4

511

Q96M43
RHQILTCQDFLCLSP

RAD51B

21

O15315
GQLTPALLHSRCLCV

RAVER1

211

Q8IY67
CGATEPCILHFQLLL

PCDHB5

96

Q9Y5E4
FHLSTRNPDGCLKCF

HSPG2

911

P98160
FHLRCLQNNGTRSCP

RAPSN

386

Q13702
QECHLLQARVASGPC

RIMBP3B

491

A6NNM3
QECHLLQARVASGPC

RIMBP3C

491

A6NJZ7
QLLGCSHFCSRTPVE

DRD5

371

P21918
QACRISPLCHNLFAL

JAK1

66

P23458
ANLSELCRSCEHPLA

KAT2A

141

Q92830
GSALQDPECFAHLLR

MEN1

406

O00255
HGESICLSPCNTLAA

RAB3GAP2

386

Q9H2M9
FFCLSQTNPLRKGCH

CACNA1F

851

O60840
LCGHTEPCVLRFQVL

PCDHB13

96

Q9Y5F0
LALRCQSPDGARHQC

FGFBP3

76

Q8TAT2
LDHRALVCSQPGLNC

IL17RA

36

Q96F46
LNDCLRHSATVSCPE

IL17RA

291

Q96F46
QELVLSGNPLHCSCA

NTRK1

141

P04629
RLPFCGDNIINHFTC

OR13C7

166

P0DN81
DHFFCEVPALLRLSC

OR2J1

176

Q9GZK6
CLGFLTQLDRASHPI

MDN1

991

Q9NU22
TGLLCHLNDACISNP

NOTCH1

366

P46531
HERASCGIAPCNNRL

KLHL6

546

Q8WZ60
HDLCLLTPNGRVNCS

LRP1B

2476

Q9NZR2
SLHVGTQCALTRRCP

MLANA

61

Q16655
CCHIFLNLVVTAPGL

NCDN

521

Q9UBB6
AVQDPHSRICFNIGC

NCF2

31

P19878
CELHGPRTLFCTEVL

FLCN

11

Q8NFG4
FRHIFLATLACLCPV

NTSR1

371

P30989
TFRFCAHCRALPSGL

MSS51

101

Q4VC12
GRDFQLCCQTPTDLH

NLRP11

356

P59045
CLQDLRLDGCHLPFF

CRB2

766

Q5IJ48
DCGRSGHPTCLQFTL

DPF3

286

Q92784
PGEAVVLRECLHTFC

RBCK1

291

Q9BYM8
PRLECSGTFSAHCIL

LMO7DN

71

F2Z398
LAPLHLCRTAASLGC

ASB18

186

Q6ZVZ8
AAACHLLLDCATFPV

DOP1B

751

Q9Y3R5
LGRQHCSILETQDPC

FAM184B

521

Q9ULE4
QTCQRSPHILAGCIL

HPS4

181

Q9NQG7
HVLLCFEGITDAPSC

DCAF4L1

141

Q3SXM0
HLLLCFVGLADTPSC

DCAF4L2

141

Q8NA75
FQPEDTCARLRCSLH

GDF3

216

Q9NR23
CFPDALDRFLCTHII

CHI3L1

41

P36222
CSTCLLQLPHDVASG

MBD1

191

Q9UIS9
LQLPHDVASGLFCKC

MBD1

196

Q9UIS9
PGRACTDTCLDHGLI

MGAT5B

696

Q3V5L5
GFILCDPSNLCHSGR

GSPT2

506

Q8IYD1
FFLLRSKGECHRSCP

PCSK5

1591

Q92824
HCLSGCPLAERNQSR

L3MBTL1

641

Q9Y468
HFFCDVAALLPLSCT

OR2M4

176

Q96R27
SREIAHFCCDFPSLL

OR2M7

171

Q8NG81
GCLLFILSQRHSPDA

MYMX

51

A0A1B0GTQ4
QKPRSRGILHSLFCC

CTDSP1

31

Q9GZU7
DSGPRCLHNGTCVDL

NOTCH3

1171

Q9UM47
QAECPHLCETSLAGR

DUSP9

131

Q99956
CPACRTPATQAIHIF

MEX3D

636

Q86XN8
RSHTGERPFICELCG

MYNN

491

Q9NPC7
HLVDISCGLPCSATL

NFX1

816

Q12986
HDDPALGLVSGQCRC

LAMB2

426

P55268
TPLHLACEQGCLASV

NFKBIA

146

P25963
ACITLTNRTGFLCHD

LDLRAD1

71

Q5T700
FLCHDQRSCIPASGV

LDLRAD1

81

Q5T700
FSRCSHLCLLSSQGP

LRP2

1706

P98164
QICSHLCLLRPGGYS

LRP2

4336

P98164
DSPEALSHLCCRLVQ

MROH6

576

A6NGR9
GDLSVALLRHFSCCP

METTL25B

261

Q96FB5
ALLRHFSCCPEVVAL

METTL25B

266

Q96FB5
VICLGNSFAHLPDCK

GNMT

136

Q14749
DHFFCEVPALLRLSC

OR2J2

176

O76002
CPFLIGRLNFCQSHV

OR52P1

161

Q8NH57
LQGRLRAVACAPHCF

KIF25-AS1

11

Q9Y6Z4
ACTQFFGEPSRHLCR

MRGPRE

161

Q86SM8
TPSQCCGHRLAADRV

KIAA1328

301

Q86T90
CNFTPQETLRVLLCH

KIR3DX1

311

Q9H7L2
RCLLCGQGFIHSSAL

PEG3

1226

Q9GZU2
PCRCTGTLRFVHQSC

MARCHF1

96

Q8TCQ1
AGLASCTCRPFLSHL

NLRC5

566

Q86WI3
CTCRPFLSHLAQGNE

NLRC5

571

Q86WI3
ACRSLDLCTQLFHGS

OXER1

326

Q8TDS5
CPTRLERCQSPFSFH

ITGB7

216

P26010
HFFCDGLPILALSCS

OR5AK3P

176

Q8NH89
QHSLLGPILSCVAVC

PARP16

201

Q8N5Y8
CSLTCAQFHPDGLIF

PRPF19

351

Q9UMS4
ALPTGGHICSYRCIN

FBLN1

486

P23142
PRLECNSAISAHCNL

ITCH

166

Q96J02
NSAISAHCNLCLPGL

ITCH

171

Q96J02
CGSTEPCVLHFQVVL

PCDHB14

96

Q9Y5E9
FCDSGPLLRLACTNT

OR6S1

181

Q8NH40
LFDPQLHDGSCICER

FAM189B

301

P81408
TFHRALDCRLAGPCE

FRMD1

506

Q8N878
NPHVCRLLGICLTST

EGFR

771

P00533
CHLLVNSRVFGPDLC

EVA1C

131

P58658
HITRVQCFPGCLTIQ

ADCY1

656

Q08828
DRQCQLTFGPDSRHC

ADAMTS4

446

O75173
HLLCVCTAALAVAPG

CD109

11

Q6YHK3
AQPLHACLVQCSREA

ESPL1

121

Q14674
GTLPCQEALSHICSL

FBH1

201

Q8NFZ0
GYLCHSCAEQRIGPL

FBH1

996

Q8NFZ0
APRHVNLSSLVSCLC

HEATR5A

1056

Q86XA9
CQLCPRAFSRSDHLA

KLF1

341

Q13351
TDITLQCPSGIIFHC

KLHL23

36

Q8NBE8
LVNPTTLNCGHSFCR

BFAR

41

Q9NZS9
FTCPDGFLLRHKICT

CALY

111

Q9NYX4
HCRNFSILLEPSGCS

B3GNT4

101

Q9C0J1
GPLVAVASCHSALLC

C5AR2

211

Q9P296
PNGSCRDFCLETEIH

DEFB108A

31

A8MXU0
INECELSAHLCPNGR

FBN1

1156

P35555
LSAHLCPNGRCVNLI

FBN1

1161

P35555
GIFLTTLHVCRRSPC

GJA5

176

P36382
QLLCCQPGLIIRSHS

GRPR

336

P30550
AVPCLEECGFLLHFR

FSCN3

171

Q9NQT6
HLDFLCCQLRPTRES

C2CD4D

196

B7Z1M9
PGCHASELCAFLVTL

DNAAF9

756

Q5TEA3
HEISVRNSGSCLCLP

ADCY3

36

O60266
SPSHFKCRSGQCVLA

CORIN

581

Q9Y5Q5
CLRTCAPVAVLQGHT

BRWD1

256

Q9NSI6
PCEICGTRFRHLQTL

BCL6

631

P41182
PAEGHCLNLFGVCRT

DEFB109B

26

Q30KR1
PLCVNARCLNTDGSF

LTBP4

1586

Q8N2S1
PHACCVGIASQTLLS

CEP192

1381

Q8TEP8
HRSAFLVLASRCPCL

DCST2

571

Q5T1A1
LETSHVFCCPNRVRG

ELP2

6

Q6IA86
PILACGNDDCRIHIF

ELP2

176

Q6IA86
HANLCLNGRCIPTVS

FBN2

501

P35556
LNGSQPIRCRCKHFA

FAM221A

116

A4D161
HHCPAFGLLASCRQL

HPS6

186

Q86YV9
AQLIDFCALSPCAHG

DNER

466

Q8NFT8
RGLPHCSCAEFQDSL

FAM53C

51

Q9NYF3
NCLGHLEACSTVLPL

S1PR2

171

O95136
HCSCRSLAELVPGVG

IFT140

556

Q96RY7
SGSRCRAHSEPLALC

DCAF15

351

Q66K64
CLACVAALAHPRTLA

NHLRC1

51

Q6VVB1
RGCDTSDCLPVLHLI

NHLRC1

76

Q6VVB1
HLLCLAASSGVPLFC

FUZ

11

Q9BT04
HCAPARLALGEALQC

PRR14L

1741

Q5THK1
CTGHPFLLSLLACFQ

PKN3

616

Q6P5Z2
VLGLSASAECHLCPV

INSM1

431

Q01101
LCGHTEPCVLRFQVL

PCDHB8

96

Q9UN66
NCSLLRCESVGPAHS

PLEKHM1

576

Q9Y4G2
NRVCCHGTVVLPTLF

SYDE2

756

Q5VT97
ESFTEGLHCDRCLPL

USH2A

541

O75445
HLALCADACAGNPFR

RGSL1

371

A5PLK6
SICILGSPRFTCGRH

RFPL1

166

O75677
GRATDGRLTCPLCQH

RNF207

51

Q6ZRF8
LLASSINGVRCPFCS

TRIM32

51

Q13049
CGRCSQDPESLLLQH

STAT2

71

P52630
CGALLQPLFTLCHAE

SSPOP

1206

A2VEC9
SGHCLPLALLCDRQD

SSPOP

1426

A2VEC9
CSCLDLLTGQRHHPG

SSPOP

3366

A2VEC9
TRLDGHFRPCLISNC

SSPOP

4406

A2VEC9
SNFVCSVCHGVLKRP

RNF151

16

Q2KHN1
AHQACRFQPSLGACV

TMEM132A

171

Q24JP5
TACTFLNHPALIRCE

TAB2

671

Q9NYJ8
THVDLRGNPFQCDCR

LGI4

151

Q8N135
PSCLRLQLDQGFHCG

NBPF6

511

Q5VWK0
QECHLLQARVASGPC

RIMBP3

491

Q9UFD9
FCDPSQLLHLRCSDT

OR7E24

196

Q6IFN5
ASLNLSGCVHCLSPD

FBXL18

346

Q96ME1
AEGCPRLQRLSLAHC

FBXL15

136

Q9H469
LLFLRCCLGSEPHNL

PRORY

26

Q9H606
CCLGSEPHNLSSLLS

PRORY

31

Q9H606
PVTDTSAELHRLCGC

RUFY4

31

Q6ZNE9
ATVRLPFCGHKNICS

WIPI2

321

Q9Y4P8
CLHVPVALGISSLDC

STARD9

2346

Q9P2P6
TIPFHACATQLGCFL

OR8U3

91

Q8NH85
HSLEAQSLRCLQPFC

NOXO1

161

Q8NFA2
PGSTCLDLLATFHCL

NOTCH4

486

Q99466
ARVNIHCPCGLVTAF

L3HYPDH

131

Q96EM0
QAGCSLRLLCPQAFS

RIOX1

291

Q9H6W3
EPQLCLSCLSQHGSI

STK36

936

Q9NRP7
ALLPGATALQCFCHL

TGFBR1

26

P36897
GHTTSVCLALRPCLN

SNED1

266

Q8TER0
PEGLLTVSSFCLQHC

CLBA1

251

Q96F83
CLPCDLGQASRFIHT

C12orf76

41

Q8N812
TLPRDSGFNHCCLNA

CNKSR2

846

Q8WXI2
LAAAQACVFCRLPAH

TMEM95

11

Q3KNT9
ACVFCRLPAHDLSGR

TMEM95

16

Q3KNT9
VPCRALTCAHLQSFD

PIAS3

336

Q9Y6X2
HIPSIGAACVCFLEL

SPG11

1246

Q96JI7
RNLGFKISLHCPCCT

TGFB2

216

P61812
CSCTISAHFNLRLPG

TRIM61

186

Q5EBN2
LLTQPLSLDCGHSFC

TRIM5

21

Q9C035
DVPCHLVSALIAGFC

UCP1

211

P25874
CPFACSSLGNLRRHQ

ZNF513

211

Q8N8E2
RIHSGDKPFRCSLCN

ZNF513

436

Q8N8E2
CCLSFPSVRDLAQHL

ZNF414

116

Q96IQ9
VGRFLNHSCCPNLLV

SETDB2

646

Q96T68
LASHRLDAGLCTCPR

ZNF565

11

Q8N9K5
QLRSHPAGRSFLCLC

ZSCAN10

311

Q96SZ4
SPRGVQAQLHCDLCA

ZFR2

311

Q9UPR6
IFRPPRASHCSICDN

ZDHHC9

146

Q9Y397
PCQACGKRFSRLDHL

ZBTB8A

311

Q96BR9
IFPLISCVGAIHCNI

XKRY

11

O14609
VSPLHLRCNICDFES

ZFHX2

816

Q9C0A1
IGDFIECPLCLLRHS

RNF19A

126

Q9NV58
LHFPSESLCRVINIC

THAP9

761

Q9H5L6
LGTHCSPDLLFFLCA

FRZB

76

Q92765
EVTAALVPCGHNLFC

MEX3A

476

A1L020
LLRCSQGGPTHCLHS

TSPAN32

251

Q96QS1
ERCQHCPLAVGRSFL

PLEKHG4B

871

Q96PX9
GRADLILPCAHSFCQ

RNF141

161

Q8WVD5
ICGVCFHRPQNEARS

SPATA31D1

601

Q6ZQQ2
ALREAVQTPCGHRFC

TRAF6

76

Q9Y4K3
FSCIIPECLQRAVHG

ZDHHC4

41

Q9NPG8
CAHLFGLSDCPVLSG

SERINC4

101

A6NH21
CGHTFCRLCLPALSQ

TRIM15

31

Q9C019
RKIHQTGDFLCPVCS

ZNF646

1071

O15015
LIHTGERPFQCSQCS

ZNF281

281

Q9Y2X9
HCGQRVLACSLPQVF

KRT10-AS1

41

Q8N816
RHGACQRSCLASQDP

SEMA6C

521

Q9H3T2
RCAGNESLLFHCPRG

SCART1

296

Q4G0T1
ESLLFHCPRGRGSQC

SCART1

301

Q4G0T1
LCHSQFLRSQAPPCT

TMEM88

66

Q6PEY1
AVNPHLFSLNILGCC

VPS45

131

Q9NRW7
HCFDLASLDPRVTVC

RRP8

331

O43159
SCSLPERHLGLVSCF

TECPR2

281

O15040
SVCILGSPRFTCGRH

RFPL3

166

O75679
CLGPAIHIANCSRNG

SEMA5B

651

Q9P283
SHRVPLDVACARGCL

PLEC

3286

Q15149
HNQPCLLVGSGRCFL

CAD

276

P27708
PQLGECSHCGRKFLS

ZC2HC1C

386

Q53FD0
CPSSIQLLCDHGASV

UACA

146

Q9BZF9
IFPLISCVGAIHCNI

XKRY2

11

A2RUG3
ICHSCDAGAVLIFLP

YTHDC2

616

Q9H6S0
CPLCGKSFSRRSNLH

ZNF205

506

O95201
LPCESCGRTFLPDHL

ZNF474

166

Q6S9Z5
CTRLAGLFHRCPEET

PIGO

631

Q8TEQ8
CHFPISTRGFSRLCV

PIEZO1

236

Q92508
SLLIDHVCSRRQFPC

WDR26

331

Q9H7D7
LGAHCSEPSCQRLDF

ZFAND2B

6

Q8WV99
LAIGANPLYCDCHLR

SLIT1

861

O75093
LLTEPLSLDCGHSFC

TRIM22

21

Q8IYM9
LRVHSGERPFQCALC

ZNF683

341

Q8IZ20
LLTEPLSIDCGHSFC

TRIM6

21

Q9C030
HCALCPAAFRLVSEL

ZNF784

66

Q8NCA9
CSATCGHLGARIQRP

ADAMTSL3

1436

P82987
HACLTLQCIPRTSGL

KLHL38

566

Q2WGJ6
PLSGHCLRCLHNTTG

LAMC3

826

Q9Y6N6
GVKLLCDVFRHPSCN

NLRP14

916

Q86W24