Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A SCN9A	8.51e-06	14	197	4	GO:0031402
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A7 CYP3A4 CYP3A5	9.32e-06	5	197	3	GO:0050649
GeneOntologyMolecularFunction	histone acetyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	1.06e-05	51	197	6	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	1.66e-05	55	197	6	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	2.75e-05	60	197	6	GO:0034212
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A7 CYP3A4 CYP3A5	5.11e-05	8	197	3	GO:0101021
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A SCN9A	1.16e-04	26	197	4	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A SCN9A	1.16e-04	26	197	4	GO:0031420
GeneOntologyMolecularFunction	N-acetyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	1.22e-04	78	197	6	GO:0008080
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP3A7 CYP3A4 CYP3A5	1.47e-04	11	197	3	GO:0101020
GeneOntologyMolecularFunction	retinoic acid 4-hydroxylase activity	CYP3A7 CYP3A4 CYP3A5	3.18e-04	14	197	3	GO:0008401
GeneOntologyMolecularFunction	histone modifying activity	SETD1B KAT2A PRDM2 DMAP1 JAK2 BRD1 CLOCK BAZ1A KAT14	4.66e-04	229	197	9	GO:0140993
GeneOntologyMolecularFunction	calmodulin binding	MYO1D IQGAP2 RYR1 RYR2 PHKA2 SCN2A SCN3A IQCJ-SCHIP1 ATP2B1	4.81e-04	230	197	9	GO:0005516
GeneOntologyMolecularFunction	N-acyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	5.25e-04	102	197	6	GO:0016410
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	5.74e-04	4	197	2	GO:0005219
GeneOntologyMolecularFunction	testosterone 16-alpha-hydroxylase activity	CYP3A4 CYP3A5	5.74e-04	4	197	2	GO:0008390
GeneOntologyMolecularFunction	acetyltransferase activity	KAT2A DMAP1 BRD1 CLOCK BAZ1A KAT14	5.82e-04	104	197	6	GO:0016407
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	IQGAP2 SNX21 ATP13A2 OSBP SH3PXD2A AVIL GAB4 PARD3	8.28e-04	199	197	8	GO:1901981
GeneOntologyMolecularFunction	vitamin D 23-hydroxylase activity	CYP3A4 CYP3A5	9.50e-04	5	197	2	GO:0062179
GeneOntologyMolecularFunction	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP3A4 CYP3A5	9.50e-04	5	197	2	GO:0062181
GeneOntologyMolecularFunction	vitamin D3 25-hydroxylase activity	CYP3A4 CYP3A5	1.42e-03	6	197	2	GO:0030343
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	1.42e-03	6	197	2	GO:0048763
GeneOntologyMolecularFunction	vitamin D 24-hydroxylase activity	CYP3A4 CYP3A5	1.42e-03	6	197	2	GO:0070576
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN2A SCN3A SCN9A	1.72e-03	52	197	4	GO:0005272
GeneOntologyMolecularFunction	ligase activity	SUCLA2 ACSM3 CAD ITCH LARS1 TTLL7 LIG3	1.74e-03	174	197	7	GO:0016874
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A SCN9A	1.62e-05	17	196	4	GO:0001518
GeneOntologyCellularComponent	junctional sarcoplasmic reticulum membrane	RYR1 RYR2 REEP5	9.28e-05	10	196	3	GO:0014701
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A SCN9A	1.48e-04	29	196	4	GO:0034706
GeneOntologyCellularComponent	nuclear chromosome	NCAPG2 DMAP1 AGO3 SIN3B POLE2 CLOCK LIG3 PBRM1 BAZ1A BRD4	1.49e-04	254	196	10	GO:0000228
GeneOntologyCellularComponent	main axon	MYO1D SCN1A SCN2A IQCJ-SCHIP1 TIAM1 PARD3	1.92e-04	89	196	6	GO:0044304
GeneOntologyCellularComponent	neuronal cell body	PCSK1 ERBB4 MYO1D KCNIP1 WASHC5 PTPRS SCN1A SCN3A VPS13A BRD1 CAD APOB ATP13A2 TTLL7 TIAM1 TPX2 PARD3 ATP2B1 HTT	3.39e-04	835	196	19	GO:0043025
GeneOntologyCellularComponent	somatodendritic compartment	PCSK1 ERBB4 MYO1D PALMD KCNIP1 WASHC5 PTPRS SCN1A SCN3A VPS13A IQCJ-SCHIP1 BRD1 CAD CALB2 DOCK10 APOB ATP13A2 TTLL7 TIAM1 TPX2 PARD3 ATP2B1 HTT NIN	5.27e-04	1228	196	24	GO:0036477
GeneOntologyCellularComponent	sarcoplasm	CMYA5 RYR1 RYR2 SCN3A REEP5 GSTM2	7.25e-04	114	196	6	GO:0016528
GeneOntologyCellularComponent	axon	PCSK1 EPS8 MYO1D SLC30A3 PTPRS SCN1A SCN2A SCN3A SCN9A IQCJ-SCHIP1 CAD CALB2 TIAM1 SLC18A1 AVIL TPX2 PARD3 HTT NIN	7.45e-04	891	196	19	GO:0030424
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A IQCJ-SCHIP1	8.23e-04	20	196	3	GO:0033268
GeneOntologyCellularComponent	smooth endoplasmic reticulum	MYO1D RYR1 RYR2 APOB	8.99e-04	46	196	4	GO:0005790
GeneOntologyCellularComponent	cell body	PCSK1 ERBB4 MYO1D KCNIP1 WASHC5 PTPRS SCN1A SCN3A VPS13A BRD1 CAD APOB ATP13A2 TTLL7 TIAM1 TPX2 PARD3 ATP2B1 HTT	1.22e-03	929	196	19	GO:0044297
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN9A	1.70e-07	6	195	4	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN9A	1.70e-07	6	195	4	IPR024583
Domain	Na_channel_asu	SCN1A SCN2A SCN3A SCN9A	2.30e-06	10	195	4	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN9A	2.30e-06	10	195	4	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN9A	2.30e-06	10	195	4	PF06512
Domain	Bromodomain_CS	KAT2A BRD1 PBRM1 BAZ1A BRD4	6.49e-06	26	195	5	IPR018359
Domain	Cyt_P450_E_grp-II	CYP3A7 CYP3A4 CYP3A5	1.10e-05	5	195	3	IPR002402
Domain	Cyt_P450_E_CYP3A	CYP3A7 CYP3A4 CYP3A5	2.19e-05	6	195	3	IPR008072
Domain	Ion_trans_dom	RYR1 RYR2 SCN1A SCN2A SCN3A SCN9A TPTE2 CNGB3	2.62e-05	114	195	8	IPR005821
Domain	Ion_trans	RYR1 RYR2 SCN1A SCN2A SCN3A SCN9A TPTE2 CNGB3	2.62e-05	114	195	8	PF00520
Domain	BROMODOMAIN_1	KAT2A BRD1 PBRM1 BAZ1A BRD4	3.92e-05	37	195	5	PS00633
Domain	Bromodomain	KAT2A BRD1 PBRM1 BAZ1A BRD4	4.47e-05	38	195	5	PF00439
Domain	IQ	MYO1D IQGAP2 SCN1A SCN2A SCN3A SCN9A IQUB	5.39e-05	93	195	7	PS50096
Domain	BROMODOMAIN_2	KAT2A BRD1 PBRM1 BAZ1A BRD4	6.51e-05	41	195	5	PS50014
Domain	Bromodomain	KAT2A BRD1 PBRM1 BAZ1A BRD4	7.33e-05	42	195	5	IPR001487
Domain	BROMO	KAT2A BRD1 PBRM1 BAZ1A BRD4	7.33e-05	42	195	5	SM00297
Domain	-	KAT2A BRD1 PBRM1 BAZ1A BRD4	7.33e-05	42	195	5	1.20.920.10
Domain	IQ	MYO1D IQGAP2 SCN1A SCN2A SCN3A SCN9A	2.03e-04	81	195	6	SM00015
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN3A SCN9A TPTE2	3.18e-04	57	195	5	IPR027359
Domain	-	SCN1A SCN2A SCN3A SCN9A TPTE2	3.18e-04	57	195	5	1.20.120.350
Domain	Ryanodine_rcpt	RYR1 RYR2	3.23e-04	3	195	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR1 RYR2	3.23e-04	3	195	2	IPR009460
Domain	RyR	RYR1 RYR2	3.23e-04	3	195	2	PF02026
Domain	RR_TM4-6	RYR1 RYR2	3.23e-04	3	195	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	3.23e-04	3	195	2	IPR013333
Domain	IQ_motif_EF-hand-BS	MYO1D IQGAP2 SCN1A SCN2A SCN3A SCN9A	3.61e-04	90	195	6	IPR000048
Domain	Nebulin	NEB NRAP	6.42e-04	4	195	2	PF00880
Domain	NEBULIN	NEB NRAP	6.42e-04	4	195	2	PS51216
Domain	NEBU	NEB NRAP	6.42e-04	4	195	2	SM00227
Domain	Nebulin	NEB NRAP	6.42e-04	4	195	2	IPR013998
Domain	Argonaute_N	AGO3 AGO1	6.42e-04	4	195	2	IPR032474
Domain	Argonaute_Mid_dom	AGO3 AGO1	6.42e-04	4	195	2	IPR032473
Domain	ArgoL2	AGO3 AGO1	6.42e-04	4	195	2	IPR032472
Domain	Nebulin_repeat	NEB NRAP	6.42e-04	4	195	2	IPR000900
Domain	ArgoN	AGO3 AGO1	6.42e-04	4	195	2	PF16486
Domain	ArgoMid	AGO3 AGO1	6.42e-04	4	195	2	PF16487
Domain	ArgoL2	AGO3 AGO1	6.42e-04	4	195	2	PF16488
Domain	ATP_grasp_subdomain_1	SUCLA2 CAD TTLL7	8.15e-04	18	195	3	IPR013815
Domain	HEAT_REPEAT	PDS5B TOGARAM1 NCAPG2 PSME4 HTT	8.23e-04	70	195	5	PS50077
Domain	IQ	MYO1D IQGAP2 SCN1A SCN3A SCN9A	8.78e-04	71	195	5	PF00612
Domain	EF-hand-dom_pair	KCNIP1 RYR1 RYR2 EHD4 CAPN8 SCN1A SCN3A SCN9A CALB2 NIN	8.99e-04	287	195	10	IPR011992
Domain	LEM	LEMD3 TMPO	1.06e-03	5	195	2	SM00540
Domain	GST_mu	GSTM2 GSTM4	1.06e-03	5	195	2	IPR003081
Domain	DUF1785	AGO3 AGO1	1.06e-03	5	195	2	SM01163
Domain	-	TDRD6 STK31	1.58e-03	6	195	2	2.40.50.90
Domain	RIH_assoc-dom	RYR1 RYR2	1.58e-03	6	195	2	IPR013662
Domain	Staphylococal_nuclease_OB-fold	TDRD6 STK31	1.58e-03	6	195	2	IPR016071
Domain	Ins145_P3_rec	RYR1 RYR2	1.58e-03	6	195	2	PF08709
Domain	RIH_assoc	RYR1 RYR2	1.58e-03	6	195	2	PF08454
Domain	ArgoL1	AGO3 AGO1	1.58e-03	6	195	2	PF08699
Domain	RIH_dom	RYR1 RYR2	1.58e-03	6	195	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	1.58e-03	6	195	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	1.58e-03	6	195	2	IPR015925
Domain	ArgoL1	AGO3 AGO1	1.58e-03	6	195	2	IPR014811
Domain	-	RYR1 RYR2	1.58e-03	6	195	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	1.58e-03	6	195	2	PF01365
Domain	Pentatricopeptide_repeat	NCAPG2 PTCD3 HTT	1.70e-03	23	195	3	IPR002885
Pathway	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	CYP3A7 CYP3A4 CYP3A5 DHDH ALDH3A1 UGT1A6 GSTM2 GSTM4	9.45e-07	70	155	8	M16794
Pathway	REACTOME_CARDIAC_CONDUCTION	KCNIP1 RYR1 RYR2 SCN1A SCN2A SCN3A SCN9A NPR1 ATP2B1	1.32e-05	130	155	9	M27454
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	CYP3A7 CYP3A4 CYP3A5 ALDH3A1 UGT1A6 GSTM2 GSTM4	1.37e-05	72	155	7	M9257
Pathway	REACTOME_MUSCLE_CONTRACTION	NEB KCNIP1 RYR1 RYR2 SCN1A SCN2A SCN3A SCN9A NPR1 ATP2B1	8.24e-05	203	155	10	M5485
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	NEB SCN1A SCN2A SCN3A SCN9A	5.83e-12	5	199	5	8812438
Pubmed	Human transcription factor protein interaction networks.	ESS2 MYO1D HSPH1 NACA KAT2A MIDEAS NKRF PRDM2 DMAP1 AGO3 NFKB1 QKI HSPA4 PTCD3 SIN3B CAD ATN1 LARS1 IRF8 MRPS18C PPARG ZHX2 LIG3 PBRM1 AGO1 TPX2 ZFHX3 KAT14 XRCC6	3.47e-09	1429	199	29	35140242
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B SETD1B HSPH1 NACA MIDEAS NEK9 NCAPG2 NKRF EHD4 TBC1D4 ADSL PSME4 WASHC5 HSPA4 PTCD3 CAD ITCH IPO7 LARS1 DOCK10 AGPS LIG3 BAZ1A CEBPZ BUB3 PARD3 ATP2B1 XRCC6	4.37e-09	1353	199	28	29467282
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	NEB SCN1A SCN2A SCN3A	5.18e-09	5	199	4	1679748
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A SCN9A	1.55e-08	6	199	4	23652591
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	LEMD3 TEX2 HSPH1 SUCLA2 NCAPG2 EHD4 SCD RWDD1 VPS13A PEX19 HSPA4 PTCD3 CAD ITCH IPO7 HECTD3 POLE2 FLVCR1 MTERF3 NCKAP5L TIAM1 CEBPZ EPHA2 TMPO PARD3 ATP2B1 XRCC6 NIN	3.27e-08	1487	199	28	33957083
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B MYO1D IQGAP2 HSPH1 KAT2A NEB RYR2 EHD4 TNRC18 ACSM3 VPS13A SCN9A ERICH6 KRT14 MAGI3 APOB TEX14 STK31 BAZ1A CEBPZ SH3PXD2A AVIL CAPRIN2 TMPO CEP57 ATP2B1 XRCC6	6.62e-08	1442	199	27	35575683
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A SCN9A	1.28e-07	9	199	4	16382098
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	1.85e-07	3	199	3	12610651
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	1.85e-07	3	199	3	18784617
Pubmed	Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	20615193
Pubmed	CYP3A Polymorphism and Chronic Mercury Intoxication.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	32146629
Pubmed	Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	17582393
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A SCN9A	1.85e-07	3	199	3	19284629
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A SCN9A	1.85e-07	3	199	3	33895391
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	1.85e-07	3	199	3	23859570
Pubmed	The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	19801957
Pubmed	Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	20621111
Pubmed	Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	20118548
Pubmed	Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	23143891
Pubmed	Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	33866277
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	1.85e-07	3	199	3	17544618
Pubmed	Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	32001245
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	1.85e-07	3	199	3	14973256
Pubmed	CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.	CYP3A7 CYP3A4 CYP3A5	1.85e-07	3	199	3	34688813
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B MYO1D HSPH1 NACA CMYA5 SUCLA2 NEK9 PRDM2 EHD4 ADSL TDRD6 HSPA4 PTCD3 CAD IPO7 LARS1 APOB AGPS LIG3 PBRM1 BAZ1A CEBPZ TMPO BUB3 ATP2B1 XRCC6	1.96e-07	1425	199	26	30948266
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	IQGAP2 HSPH1 PEG3 NACA SUCLA2 MIDEAS NKRF AGO3 CSNK1G1 RAMAC QKI PTCD3 COL11A1 IPO7 APOB AGPS PBRM1 BAZ1A CEBPZ EPHA2 TPX2 TMPO BUB3 PARD3 XRCC6	3.47e-07	1371	199	25	36244648
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A ARSB	4.97e-07	12	199	4	8169823
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PDS5B ESS2 MIDEAS PRDM2 DMAP1 BRD1 SIN3B IPO7 PIAS4 LIG3 PBRM1 BAZ1A BRD4 TPX2 TMPO XRCC6	5.11e-07	608	199	16	36089195
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERBB4 KAT2A ABCA8 NKRF DMAP1 AGO3 SFXN2 BRD1 PTCD3 ITCH ATN1 HECTD3 VPS50 NCKAP5L PBRM1 ARSB BRD4 CAPRIN2 ZFHX3 PARD3 KAT14 NIN	5.15e-07	1116	199	22	31753913
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PDS5B NKRF DMAP1 NFKB1 PTCD3 IPO7 LIG3 PBRM1 BAZ1A CEBPZ BRD4 TPX2 BUB3 HYDIN	6.16e-07	469	199	14	27634302
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN3A SCN9A	7.14e-07	13	199	4	15123669
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A	7.35e-07	4	199	3	17537961
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	7.35e-07	4	199	3	35801810
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A	7.35e-07	4	199	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A	7.35e-07	4	199	3	29578003
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	7.35e-07	4	199	3	8974318
Pubmed	Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.	CYP3A7 CYP3A4 CYP3A5	7.35e-07	4	199	3	34689350
Pubmed	CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.	CYP3A7 CYP3A4 CYP3A5	7.35e-07	4	199	3	18978522
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MIDEAS NEK9 NKRF DMAP1 USP15 SIN3B CAD CEBPZ BRD4 TPX2 TMPO LRBA BUB3 PARD3 HTT	7.37e-07	549	199	15	38280479
Pubmed	Gene expression profile of aging and its retardation by caloric restriction.	CYP3A4 CYP3A5 HSPH1 SCD PPARG HTT	9.26e-07	57	199	6	10464095
Pubmed	Interaction network of human early embryonic transcription factors.	MIDEAS PRDM2 DMAP1 TNRC18 ATN1 ZHX2 PIAS4 LIG3 PBRM1 BAZ1A ZFHX3 KAT14	9.84e-07	351	199	12	38297188
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	HSPH1 RYR1 PRDM2 JAK2 PARP4 TBC1D4 SCN3A VPS13A CA5A CFAP47 SIN3B MAGI3 AGPS LIG3 DENND6A TMPO XRCC6	1.34e-06	736	199	17	29676528
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LEMD3 HSPH1 NEK9 NCAPG2 DMAP1 TBC1D4 ADSL PTPRS HYAL3 REEP5 USP15 CA5A NPR1 ARV1 PRSS23 GXYLT2 EPHA2 TPX2 TMPO FUT8 ATP2B1 HTT	1.72e-06	1201	199	22	35696571
Pubmed	Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes.	CYP3A7 CYP3A4 CYP3A5	1.83e-06	5	199	3	24168324
Pubmed	Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.	CYP3A7 CYP3A4 CYP3A5	1.83e-06	5	199	3	11266076
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	1.83e-06	5	199	3	24337656
Pubmed	Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.	CYP3A7 CYP3A4 CYP3A5	1.83e-06	5	199	3	11093772
Pubmed	Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.	CYP3A7 CYP3A4 CYP3A5	1.83e-06	5	199	3	14559847
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	CYP3A4 CYP3A5 ACSM3 UGT1A6 APOB PPARG	2.22e-06	66	199	6	20679960
Pubmed	Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women.	CYP3A7 CYP3A4 CYP3A5 UGT1A6	2.33e-06	17	199	4	19424794
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYO1D LEMD3 EHD4 TBC1D4 WASHC5 PTPRS NFKB1 VPS13A PEX19 KRT14 CAD IPO7 TPTE2 FLVCR1 NCKAP5L TIAM1 CEBPZ TMPO ATP2B1 NIN	2.89e-06	1049	199	20	27880917
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	LAPTM4A LEMD3 ACP2 HSPH1 NACA NEK9 NCAPG2 JAK2 AGO3 PTPRS VPS13A TMEM192 REEP5 ITCH APOB ATE1 EPHA2 LRBA FUT8 CDH17	3.43e-06	1061	199	20	33845483
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO1D NACA RYR1 PRDM2 TBC1D4 VPS13A DOCK10 CAPRIN2 OTOG	3.47e-06	208	199	9	33230847
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	MYO1D IQGAP2 HSPH1 NACA IST1 EHD4 HSPA4 PTCD3 KRT14 CAD LIG3 CEBPZ TMPO BUB3 XRCC6	3.68e-06	626	199	15	33644029
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	EPS8 SETD1B TEX2 AGO3 WASHC5 SCN9A HSPA4 SIN3B MAGI3 PBRM1 AGO1 PARD3 HTT	4.05e-06	475	199	13	31040226
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MYO1D NEB RYR1 RYR2 PARP4 VPS13A AMPD1 IPO7 HECTD3 STK31 LIG3 OSBP PBRM1 ATP2B1 CDH17	4.63e-06	638	199	15	31182584
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PDS5B PEG3 ZNF202 ZNF280B KAT2A NFKB1 NRAP MTERF3 IRF8 CLOCK PIAS4 PBRM1 BAZ1A PLXNC1 BRD4 ZFHX3 XRCC6	4.64e-06	808	199	17	20412781
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	KAT2A BRD1 SIN3B PBRM1 BAZ1A BRD4	4.72e-06	75	199	6	25593309
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PDS5B ESS2 HSPH1 KAT2A MIDEAS NCAPG2 PRDM2 TNRC18 QKI HSPA4 SIN3B CAD IPO7 LARS1 PPARG BRD4 TPX2 TMPO BUB3 XRCC6	6.08e-06	1103	199	20	34189442
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	HSPH1 NACA NKRF PARP4 AGO3 HSPA4 CFAP47 CAD IPO7 LARS1 TPX2 BUB3 XRCC6	6.17e-06	494	199	13	26831064
Pubmed	The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.	IQGAP2 HSPH1 IST1 SFXN2 HSPA4 PTCD3 CAD IPO7 LIG3 TMPO XRCC6	6.25e-06	350	199	11	26549023
Pubmed	Pain without nociceptors? Nav1.7-independent pain mechanisms.	SCN3A SCN9A AVIL	6.35e-06	7	199	3	24440715
Pubmed	The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.	CYP3A7 CYP3A4 CYP3A5	6.35e-06	7	199	3	11137287
Pubmed	Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients.	CYP3A7 CYP3A4 CYP3A5	6.35e-06	7	199	3	19842932
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	PEG3 CMYA5 NEB NEK9 RYR1 PARP4 TBC1D4 AMPD1 ITCH NRAP IPO7 PARD3 XRCC6	6.58e-06	497	199	13	23414517
Pubmed	Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.	CYP3A7 CYP3A4 CYP3A5 PRDM2 UGT1A6 PPARG LIG3 XRCC6	6.62e-06	170	199	8	19064572
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TEX2 NACA DMAP1 SCD REEP5 COL11A1 CAD IPO7 LARS1 APOB GSTM2 LIG3 TRAF4 TPX2 BUB3 XRCC6	8.03e-06	754	199	16	35906200
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ZGRF1 NEB NKRF CAD LPIN3 PBRM1 TPX2 TMPO LRBA	8.99e-06	234	199	9	36243803
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1B LEMD3 NKRF DMAP1 DHX35 USP15 HSPA4 CAD AGPS PBRM1 CEBPZ TPX2	9.90e-06	440	199	12	34244565
Pubmed	A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.	CYP3A7 CYP3A4 CYP3A5	1.01e-05	8	199	3	20147896
Pubmed	Significant determinants of mouse pain behaviour.	SCN3A SCN9A AVIL	1.01e-05	8	199	3	25101983
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MYO1D HSPH1 NKRF TNRC18 TBC1D4 ADSL DHX35 USP15 HSPA4 CAD ITCH ATN1 IPO7 LARS1 LIG3 CEBPZ EPHA2 TMPO BUB3 PARD3 XRCC6	1.08e-05	1247	199	21	27684187
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	LEMD3 NCAPG2 ADSL PTPRS PEX19 TMEM192 ANKMY2 QKI HSPA4 PTCD3 IPO7 POLE2 TPTE2 ATE1 NCKAP5L EPHA2 FUT8 ATP2B1	1.41e-05	974	199	18	28675297
Pubmed	Identification of genetic variants associated with response to statin therapy.	CYP3A4 CYP3A5 APOB	1.51e-05	9	199	3	19667110
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A	1.51e-05	9	199	3	15746173
Pubmed	Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide.	CYP3A4 CYP3A5 ALDH3A1	1.51e-05	9	199	3	18496131
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SUCLA2 NEK9 TMEFF2 JAK2 TNRC18 TBC1D4 PTPRS REEP5 USP15 ITCH SLC16A9 FLVCR1 MAGI3 ZHX2 PIAS4 PLPP1 SH3PXD2A ZFHX3 LRBA SYTL1 PARD3 ATP2B1 HTT	1.61e-05	1489	199	23	28611215
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	CYP3A7 CYP3A4 CYP3A5 ABCA8 ABCD4 ALDH3A1 GSTM2 GSTM4	1.67e-05	193	199	8	19343046
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	PDS5B HSPH1 MIDEAS DMAP1 LARS1 LIG3 PBRM1 BAZ1A BRD4 TPX2 XRCC6	1.88e-05	394	199	11	27248496
Pubmed	Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.	CYP3A4 SCN1A SCN2A	2.15e-05	10	199	3	20602612
Pubmed	Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.	CYP3A7 CYP3A4 CYP3A5	2.15e-05	10	199	3	12865317
Pubmed	AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.	HSPH1 NACA HSPA4 IPO7 LARS1 GSTM2 BUB3 XRCC6	2.15e-05	200	199	8	35546148
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	TSSK6 MYO1D HSPH1 NEK9 JAK2 NFKB1 CAD IPO7 DENND6A BUB3 XRCC6	2.21e-05	401	199	11	25852190
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ESS2 LEMD3 NEK9 ADSL BRD1 USP15 PTCD3 LIG3 YJU2 PBRM1 TPX2 LRBA XRCC6 NIN	2.34e-05	645	199	14	25281560
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PDS5B MYO1D NACA NKRF EHD4 HSPA4 KRT14 CAD IPO7 LARS1 AGPS LIG3 PBRM1 BAZ1A CEBPZ TMPO ATP2B1 XRCC6	2.72e-05	1024	199	18	24711643
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	HSPH1 PHKA2 TBC1D4 ADSL SCD USP15 HSPA4 CAD IPO7 HECTD3 LARS1 AGPS BUB3	2.83e-05	571	199	13	37167062
Pubmed	Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.	CYP3A4 CYP3A5 APOB PPARG LIG3	2.90e-05	62	199	5	20403997
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	IQGAP2 HSPH1 NACA SUCLA2 NCAPG2 NKRF EHD4 NFKB1 RWDD1 PEX19 REEP5 HSPA4 PTCD3 CAD IPO7 LARS1 MRPS18C LIG3 CEBPZ TMPO ATP2B1 XRCC6	2.93e-05	1440	199	22	30833792
Pubmed	Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.	CYP3A7 CYP3A4	3.26e-05	2	199	2	28986474
Pubmed	Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression.	NFKB1 PPARG	3.26e-05	2	199	2	20573495
Pubmed	The combination of CYP3A422 and CYP3A53 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.	CYP3A4 CYP3A5	3.26e-05	2	199	2	28704257
Pubmed	Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.	CYP3A4 CYP3A5	3.26e-05	2	199	2	15900284
Pubmed	Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage.	CYP3A4 CYP3A5	3.26e-05	2	199	2	15900215
Pubmed	Gender differences in food allergy depend on the PPAR γ/NF-κB in the intestines of mice.	NFKB1 PPARG	3.26e-05	2	199	2	33974930
Pubmed	CYP3A4 and CYP3A5 polymorphisms and blood pressure response to amlodipine among African-American men and women with early hypertensive renal disease.	CYP3A4 CYP3A5	3.26e-05	2	199	2	19907160
Pubmed	Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.	KIR2DL5B KIR2DL5A	3.26e-05	2	199	2	12185535
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	3.26e-05	2	199	2	19694741
Pubmed	Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors in Kidney Transplant Recipients of European Ancestry.	CYP3A4 CYP3A5	3.26e-05	2	199	2	33512723
Pubmed	Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers.	CYP3A4 CYP3A5	3.26e-05	2	199	2	30166405
Cytoband	16q22.2	IST1 CALB2 HYDIN	1.16e-04	22	199	3	16q22.2
Cytoband	17q11-q12	MYO1D TRAF4	2.77e-04	6	199	2	17q11-q12
Cytoband	7q21.1	CYP3A4 CYP3A5	5.15e-04	8	199	2	7q21.1
Cytoband	14q24.3	MIDEAS NEK9 ABCD4 FUT8	7.40e-04	93	199	4	14q24.3
Cytoband	12q14	LEMD3 USP15	1.00e-03	11	199	2	12q14
Cytoband	2q24	SCN3A SCN9A	1.00e-03	11	199	2	2q24
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A SCN9A	3.86e-07	9	137	4	1203
GeneFamily	Cytochrome P450 family 3	CYP3A7 CYP3A4 CYP3A5	2.32e-05	8	137	3	1002
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	1.70e-04	3	137	2	287
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL5B KIR2DL4 KIR2DL5A	3.20e-04	18	137	3	620
GeneFamily	Zinc fingers GRF-type\|Topoisomerases	ZGRF1 NEIL3	1.17e-03	7	137	2	135
GeneFamily	LEM domain containing	LEMD3 TMPO	1.17e-03	7	137	2	1087
GeneFamily	Argonaute/PIWI family	AGO3 AGO1	1.55e-03	8	137	2	408
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PDS5B EPS8 TOGARAM1 PSME4 NFKB1 VPS13A ANKMY2 QKI USP15 SCHIP1 ITCH IPO7 MAMLD1 ZHX2 CLOCK TIAM1 BAZ1A ZFHX3 PARD3 FUT8 ATP2B1	2.33e-06	856	198	21	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	EPS8 ADSL VPS13A ANKMY2 QKI SCHIP1 IPO7 MAMLD1 ZHX2 CLOCK TIAM1 BAZ1A PARD3 FUT8 ATP2B1	2.88e-06	466	198	15	M13522
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PEG3 RAP1GAP2 NEB RYR2 PRDM2 TMEFF2 EHD4 SCN1A SCN2A SCN3A SCN9A BRD1 COL11A1 KRT14 CALB2 SLC16A9 MAGI3 TTLL7 PLXNC1 SH3PXD2A CAPRIN2 ZFHX3 ATP2B1 HYDIN	3.56e-06	1106	198	24	M39071
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	TOGARAM1 ADSL NFKB1 QKI POLE2 ZHX2 BAZ1A ATP2B1	1.51e-05	145	198	8	M1810
Coexpression	GSE14350_IL2RB_KO_VS_WT_TEFF_UP	NEK9 PHKA2 PTPRS SCN1A VPS13A ZHX2 GSTM4 TIAM1 PLXNC1	2.27e-05	200	198	9	M3423
Coexpression	GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN	EPS8 IQGAP2 MIDEAS NCAPG2 PTPRS SCN3A PTCD3 TRAF4 TIAM1	2.27e-05	200	198	9	M8656
Coexpression	GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP	PDS5B MIDEAS JAK2 ACSM3 C4orf33 NUDT7 TEX14 SLC18A1 LRBA	2.27e-05	200	198	9	M3142
Coexpression	GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN	EPS8 IQGAP2 NCAPG2 WDR35 REEP5 MAGI3 PBRM1 NIN	3.84e-05	165	198	8	M8121
Coexpression	JACKSON_DNMT1_TARGETS_UP	HSPH1 JAK2 REEP5 TRAF4 CEBPZ EPHA2	4.29e-05	84	198	6	M1604
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	HSPH1 ZNF202 NEK9 PRDM2 JAK2 TBC1D4 SCD SCN9A ANKMY2 QKI USP15 HSPA4 IPO7 HECTD3 MTERF3 GSTM4 YJU2 BAZ1A PLXNC1 TMPO LRBA BUB3 CEP57	4.97e-05	1215	198	23	M41122
Coexpression	JACKSON_DNMT1_TARGETS_UP	HSPH1 JAK2 REEP5 TRAF4 CEBPZ EPHA2	7.61e-05	93	198	6	MM1185
Coexpression	HALLMARK_UV_RESPONSE_DN	TOGARAM1 PRDM2 NFKB1 SCHIP1 COL11A1 PPARG ATP2B1	1.16e-04	144	198	7	M5942
Coexpression	LAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B	EPS8 IQGAP2 TBC1D4 QKI MAGI3 PPARG	1.34e-04	103	198	6	M39240
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	ERBB4 RAP1GAP2 NEB TMEFF2 SCN2A SCN3A SCN9A CALB2 TTLL7 PLXNC1 SLC18A1 SH3PXD2A ZFHX3	1.34e-04	506	198	13	M39067
Coexpression	GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN	LAPTM4A IQGAP2 TEX2 TBC1D4 PTPRS SCN9A IRF8 TRAF4	1.38e-04	198	198	8	M4959
Coexpression	GSE29618_BCELL_VS_PDC_DN	IQGAP2 TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.38e-04	198	198	8	M4942
Coexpression	GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN	HSPH1 NCAPG2 JAK2 SCN3A SCN9A ANKMY2 LARS1 IRF8	1.38e-04	198	198	8	M5001
Coexpression	GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP	TEX2 ACSM3 PTCD3 SIN3B AGO1 CAPRIN2 LRBA EPHA1	1.42e-04	199	198	8	M3257
Coexpression	GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP	TEX2 TBC1D4 PTPRS SCN9A IRF8 ZHX2 ATP13A2 TRAF4	1.42e-04	199	198	8	M4970
Coexpression	GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN	TEX2 TBC1D4 PTPRS SCN9A ITCH IRF8 ZHX2 TRAF4	1.42e-04	199	198	8	M4964
Coexpression	VANTVEER_BREAST_CANCER_ESR1_UP	ERBB4 TOGARAM1 NEK9 PEX19 LRBA FUT8 HTT	1.43e-04	149	198	7	M393
Coexpression	GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	PDS5B ZGRF1 HSPH1 MIDEAS PRDM2 AGO1 TIAM1 EPHA2	1.47e-04	200	198	8	M291
Coexpression	GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN	LEMD3 TBC1D4 AGO3 PTCD3 SIN3B PRSS23 OSBP ARSB	1.47e-04	200	198	8	M4538
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN	EPS8 TOGARAM1 NKRF JAK2 NFKB1 NPR1 MTERF3 OSBP	1.47e-04	200	198	8	M6045
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP	RAP1GAP2 C4orf33 ITCH IPO7 SLC16A9 DOCK10 GSTM2 CDH17	1.47e-04	200	198	8	M6447
Coexpression	GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN	ZNF202 KAT2A RYR2 ME3 COL11A1 CAD PLPP1 EPHA1	1.47e-04	200	198	8	M5560
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	PDS5B IQGAP2 HSPH1 WASHC5 RWDD1 MTERF3 DOCK10 TTLL7 PBRM1 BAZ1A CEBPZ PLXNC1 CAPRIN2 CEP57 NIN	1.49e-04	656	198	15	M18979
Coexpression	BENPORATH_ES_1	ZGRF1 RAP1GAP2 NCAPG2 HSPA4 POLE2 PLPP1 CEBPZ CAPRIN2 TMPO BUB3 EPHA1	1.56e-04	379	198	11	M1871
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB RYR2 CAPN8 SCN2A SCN9A COL11A1 APOB HYDIN OTOG	1.39e-07	184	197	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB RYR2 CAPN8 SCN2A SCN9A COL11A1 APOB HYDIN OTOG	1.39e-07	184	197	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB RYR2 CAPN8 SCN2A SCN9A COL11A1 APOB HYDIN OTOG	1.39e-07	184	197	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	PALMD NCAPG2 RYR1 ABCD4 ANKMY2 POLE2 AGO1 TPX2 TMPO	2.48e-07	197	197	9	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 CMYA5 ITGAD PTPRS SCN3A IRF8 SH3PXD2A EPHA2	1.22e-06	176	197	8	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 CMYA5 ITGAD PTPRS SCN3A IRF8 SH3PXD2A EPHA2	1.22e-06	176	197	8	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 QKI CALB2 DOCK10 GSTM2 PARD3	1.77e-06	185	197	8	bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.84e-06	186	197	8	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.84e-06	186	197	8	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 QKI COL11A1 DOCK10 ZHX2 TRAF4 PARD3	1.91e-06	187	197	8	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 QKI COL11A1 DOCK10 ZHX2 TRAF4 PARD3	1.91e-06	187	197	8	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ERBB4 CMYA5 RYR2 TMEFF2 JAK2 PSME4 QKI NRAP	2.15e-06	190	197	8	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PALMD ME3 EHD4 ADAMTS18 NPR1 PRSS23 GXYLT2 ART4	2.24e-06	191	197	8	54bbccc554f43ba2ebdf9ea191b94c8f16081b53
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PALMD ME3 EHD4 ADAMTS18 NPR1 PRSS23 GXYLT2 ART4	2.24e-06	191	197	8	0e8a73f01e3ec95d242c09231bcf3790324d0a67
ToppCell	LPS_only-Myeloid-Dendritic_cells-pDC\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 RAP1GAP2 ZNF280B ZAR1L PTPRS IRF8 ATP13A2	2.39e-06	135	197	7	0afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYP3A5 CMYA5 CAPN8 MMP28 PPARG TIAM1 SH3PXD2A EPHA2	2.42e-06	193	197	8	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB4 CMYA5 KCNIP1 SCN1A SCN2A SCN9A COL11A1 HYDIN	3.04e-06	199	197	8	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 RAP1GAP2 DHDH ERICH6 POLE2 LCT OTOG	3.67e-06	144	197	7	013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RYR1 JAK2 TBC1D4 NAALAD2 MAMLD1 IRF8 ARSB	1.09e-05	170	197	7	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.13e-05	171	197	7	debbb071d260639b16269c94d172766908325c58
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.13e-05	171	197	7	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR1 JAK2 TBC1D4 MMP28 IRF8 DOCK10 ARSB	1.18e-05	172	197	7	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPH1 TMEFF2 SCD HYAL3 C4orf33 ARV1 POLE2	1.22e-05	173	197	7	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPH1 TMEFF2 SCD HYAL3 C4orf33 ARV1 POLE2	1.22e-05	173	197	7	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZGRF1 NCAPG2 EHD4 LCT TPX2 TMPO NEIL3	1.27e-05	174	197	7	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PALMD NCAPG2 ME3 PRSS23 GXYLT2 TPX2 NEIL3	1.32e-05	175	197	7	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNRC18 PTCD3 SCHIP1 MAGI3 DENND6A CAPRIN2 CEP57	1.32e-05	175	197	7	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCDC2C TEX2 ITGAD PTPRS IRF8 ATP13A2 EPHA2	1.37e-05	176	197	7	d4075796c38b775fe721abb47426e662a0d415e3
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 CMYA5 RYR2 TBC1D4 PSME4 IPO7 CLOCK	1.37e-05	176	197	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 IQGAP2 RYR1 TBC1D4 IRF8 DOCK10 ARSB	1.42e-05	177	197	7	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PALMD EHD4 NPR1 PRSS23 GXYLT2 PLPP1 ART4	1.47e-05	178	197	7	0139b42494c1186390b12106dea7957e2b6717c2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 CALB2 DOCK10 GSTM2 PARD3	1.47e-05	178	197	7	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 TBC1D4 PTPRS SCN3A IRF8 DOCK10 EPHA2	1.52e-05	179	197	7	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 DCDC2C KCNIP1 CALB2 DOCK10 MAGI3 PARD3	1.52e-05	179	197	7	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 TBC1D4 PTPRS SCN3A IRF8 DOCK10 EPHA2	1.52e-05	179	197	7	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 CMYA5 ITGAD PTPRS IRF8 ATP13A2 EPHA2	1.64e-05	181	197	7	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LEMD3 AGO3 NPR1 MAMLD1 PLPP1 ART4 PLXNC1	1.64e-05	181	197	7	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 CMYA5 ITGAD PTPRS IRF8 ATP13A2 EPHA2	1.64e-05	181	197	7	e2481291c236105774c53883e6f20da11941df9b
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PALMD EHD4 NPR1 PRSS23 GXYLT2 PLPP1 ART4	1.70e-05	182	197	7	345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 KCNIP1 CALB2 DOCK10 PARD3	1.70e-05	182	197	7	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 KCNIP1 CALB2 DOCK10 PARD3	1.82e-05	184	197	7	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	1.82e-05	184	197	7	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 ERBB4 MYO1D CAPN8 MAGI3 PARD3 FUT8	1.89e-05	185	197	7	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 KCNIP1 CALB2 DOCK10 PARD3	1.89e-05	185	197	7	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	ERBB4 MYO1D CAPN8 MAGI3 CYP4Z2P EPHA2 PARD3	1.95e-05	186	197	7	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	EPS8 JAK2 NFKB1 SCN9A IQCJ-SCHIP1 IRF8 ATP2B1	1.95e-05	186	197	7	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	EPS8 JAK2 NFKB1 SCN9A IQCJ-SCHIP1 IRF8 ATP2B1	1.95e-05	186	197	7	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	control-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TEX2 TBC1D4 PTPRS SCN9A IRF8 TRAF4 EPHA2	1.95e-05	186	197	7	fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 ERBB4 IQGAP2 KCNIP1 CALB2 DOCK10 PARD3	2.02e-05	187	197	7	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	NEK9 SCN9A TMEM192 LIG3 TRAF4 EPHA2 NIN	2.02e-05	187	197	7	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	P15-Endothelial-unknown_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEFF2 EHD4 SLC16A9 TEX14 ATP13A2 PLPP1 ZFHX3	2.02e-05	187	197	7	d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCell	Healthy_donor-pDC\|World / disease group, cell group and cell class (v2)	TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.02e-05	187	197	7	aa2cc54487d3c5045ac0c93560944c5a55878e27
ToppCell	control-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TEX2 SCN9A SCHIP1 IRF8 ATP13A2 TRAF4 EPHA2	2.02e-05	187	197	7	c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCell	P15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEFF2 EHD4 SLC16A9 TEX14 ATP13A2 PLPP1 ZFHX3	2.02e-05	187	197	7	60f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	ERBB4 MYO1D RYR2 SCN3A DOCK10 TTLL7 PLPP1	2.09e-05	188	197	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Control-Myeloid-pDC\|Control / Disease group, lineage and cell class	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.16e-05	189	197	7	46770b99da42f11f10cfc67cea8562342d60b867
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAP1GAP2 SLC30A3 RYR2 VPS13A SLC6A7 ATP2B1 NIN	2.16e-05	189	197	7	a75226616340045b581d08429d2e123e041dee55
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	9a91bf1ea105029e6412d0d9060bca325299ce26
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	39c8ddc2639bf3e986dae11fbae61a735614b604
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	2c1c079fd411c03bc3f383aa927eea9446716960
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	18dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC30A3 RYR2 VPS13A MAGI3 SLC6A7 ATP2B1 NIN	2.24e-05	190	197	7	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	adffa93635da10251f28b2089fd96b189775c8b4
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.24e-05	190	197	7	a95aea3aa707fc4574810706341a5f32b3d00209
ToppCell	COVID-19_Moderate-pDC\|World / disease group, cell group and cell class	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.31e-05	191	197	7	93adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCell	Control-pDC\|Control / Disease condition and Cell class	TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.31e-05	191	197	7	543e1437a52d04436862dd1c27b4fae95c44fcc8
ToppCell	COVID-19_Moderate-pDC\|COVID-19_Moderate / disease group, cell group and cell class	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.31e-05	191	197	7	9d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCell	Control-pDC-\|Control / Disease condition and Cell class	TBC1D4 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.31e-05	191	197	7	1d7b0fae4d114d6db933c18b4eb2066ffa61356d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	HSPH1 IST1 PRDM2 WDR35 BRD1 TRAF4 ATP2B1	2.31e-05	191	197	7	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	EPS8 ERBB4 CAPN8 SCD SCN1A MMP28 MAGI3	2.31e-05	191	197	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Healthy-pDC\|World / disease group, cell group and cell class	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.31e-05	191	197	7	6e1d825dc33b915b95f13ccd237a552160a4be98
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAPTM4A TMEFF2 EHD4 SLC16A9 TEX14 PLPP1 ZFHX3	2.39e-05	192	197	7	53d438e35c14e7656585942b788459e6d843c555
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PALMD ME3 NPR1 SCHIP1 MMP28 MAMLD1 PRSS23	2.39e-05	192	197	7	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KCNIP1 QKI CALB2 DOCK10 TIAM1 PARD3	2.39e-05	192	197	7	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	ERBB4 MYO1D CAPN8 MAGI3 CYP4Z2P EPHA2 PARD3	2.39e-05	192	197	7	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAPTM4A TMEFF2 EHD4 SLC16A9 TEX14 PLPP1 ZFHX3	2.39e-05	192	197	7	9a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PALMD ME3 NPR1 SCHIP1 MMP28 MAMLD1 PRSS23	2.39e-05	192	197	7	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	Healthy-pDC\|Healthy / disease group, cell group and cell class	TEX2 PTPRS SCN9A IRF8 ATP13A2 TRAF4 EPHA2	2.39e-05	192	197	7	33d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC2C KCNIP1 SCN3A SCN9A TSPEAR PLPP1 ART4	2.47e-05	193	197	7	040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC2C KCNIP1 SCN3A SCN9A TSPEAR PLPP1 ART4	2.47e-05	193	197	7	e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCell	control-pDC\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TEX2 SCN9A SCHIP1 IRF8 ATP13A2 TRAF4 EPHA2	2.47e-05	193	197	7	30a6559c9a9e8941861cb259b4836acccc427e68
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 CMYA5 CAPN8 SCN2A SCN3A PPARG LRBA	2.56e-05	194	197	7	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KCNIP1 QKI CALB2 DOCK10 TIAM1 PARD3	2.56e-05	194	197	7	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KCNIP1 QKI CALB2 DOCK10 TIAM1 PARD3	2.56e-05	194	197	7	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK1 HSPH1 RYR2 SCN2A VPS13A MAGI3 ATP2B1	2.64e-05	195	197	7	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPS8 ERBB4 MYO1D CAPN8 MAGI3 LRBA PARD3	2.64e-05	195	197	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQGAP2 NACA PTPRS SCN9A IRF8 ATP13A2 EPHA2	2.64e-05	195	197	7	06051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQGAP2 NACA PTPRS SCN9A IRF8 ATP13A2 EPHA2	2.64e-05	195	197	7	3aa44633c72658545aa2b35bf9d532c62f36a451
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 ADAMTS18 AMPD1 NRAP TPX2 NEIL3	2.70e-05	132	197	6	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	droplet-Tongue-TONGUE\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAPTM4A PEG3 SLC16A9 TIAM1 PARD3 ATP2B1 EPHA1	2.73e-05	196	197	7	44a30b1a5f3d8c845e5f3bd17d8102a7449f555b
ToppCell	droplet-Tongue-TONGUE-1m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAPTM4A PEG3 SLC16A9 TIAM1 PARD3 ATP2B1 EPHA1	2.73e-05	196	197	7	9935bdb10789e8cfc922dca526ca3bf8317fe270
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAPTM4A PEG3 SLC16A9 TIAM1 PARD3 ATP2B1 EPHA1	2.73e-05	196	197	7	a85f5f1e6acc798e9e02b1a21e0ffe87a323c333
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KCNIP1 QKI CALB2 DOCK10 TIAM1 PARD3	2.73e-05	196	197	7	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	HSPH1 ZNF280B ZAR1L FLVCR1 IRF8 DOCK10 ATP13A2	2.91e-05	198	197	7	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	wk_08-11-Epithelial-Proximal_epithelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK1 RAP1GAP2 CAPN8 SCN3A KRT14 SLC18A1 SYTL1	2.91e-05	198	197	7	9895f1d65d18d939f3974a914ee41c6d5575e765
ToppCell	Caecum-T_cell-cycling_gd_T\|Caecum / Region, Cell class and subclass	NCAPG2 RYR1 DHDH KIR2DL4 CA5A TPX2 CDH17	2.91e-05	198	197	7	5b719b67f8384863077070e1eb7e04a320e6dab4
ToppCell	Caecum-(1)_T_cell-(18)_cycling_gd_T\|Caecum / shred on region, Cell_type, and subtype	NCAPG2 RYR1 DHDH KIR2DL4 CA5A TPX2 CDH17	2.91e-05	198	197	7	64278d8831c81874937e76b561c53928dfc437c5
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZGRF1 PALMD NCAPG2 POLE2 TPX2 NEIL3	2.94e-05	134	197	6	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB4 MYO1D MAGI3 ZHX2 LRBA PARD3 FUT8	3.01e-05	199	197	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCDC2C KCNIP1 SCN9A PRSS23 PPARG PLPP1 ART4	3.11e-05	200	197	7	76e90231aa94afc12e618da8ae314c51644acab4
Drug	glutathione reduced	CYP3A7 CYP3A4 CYP3A5 NACA ME3 CKM DHDH NFKB1 ALDH3A1 HSPA4 NPR1 MMP28 UGT1A6 PPARG GSTM2 GSTM4 SLC6A7 HTT	1.08e-06	534	198	18	CID000000745
Drug	Phenytoin	CYP3A7 CYP3A4 CYP3A5 RYR2 CKM SCN1A NFKB1 SCN2A SCN3A COL11A1 UGT1A6 MRPS18C GSTM2 LRBA CEP57	1.53e-06	385	198	15	ctd:D010672
Drug	R 478	RYR1 RYR2 HSPA4 PPARG	1.75e-06	11	198	4	CID000084223
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SETD1B ZNF202 JAK2 NFKB1 DHX35 TRMO ZHX2 YJU2 TMPO ZFHX3	2.78e-06	172	198	10	2330_DN
Drug	Aroclor 1254	CYP3A7 CYP3A4 CYP3A5 RYR1 NFKB1 ALDH3A1 UGT1A6 PPARG GSTM2 GSTM4 PBRM1	2.79e-06	213	198	11	CID000040470
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	PDS5B EPS8 PRDM2 ZHX2 TIAM1 BAZ1A TPX2 TMPO FUT8 ATP2B1	4.84e-06	183	198	10	7498_DN
Drug	phthalic acid	CYP3A4 CYP3A5 DHDH ALDH3A1 APOB PPARG ART4 XRCC6	5.09e-06	109	198	8	CID000001017
Drug	NSC759576	CYP3A7 IQGAP2 CYP3A4 CYP3A5 RYR1 RYR2 CKM NFKB1 NPR1 APOB	7.07e-06	191	198	10	CID000003075
Drug	DM-nitrophen	RYR1 TMEFF2 CALB2 TMPO	9.30e-06	16	198	4	CID000003083
Drug	Zonisamide	SCN1A SCN2A SCN3A SCN9A	1.21e-05	17	198	4	DB00909
Drug	Alfentanil	CYP3A7 CYP3A4 CYP3A5	1.27e-05	6	198	3	ctd:D015760
Drug	MBED	RYR1 RYR2 HSPA4	1.27e-05	6	198	3	CID000129958
Drug	3,4-dioctylphthalic acid	PDS5B CYP3A7 ERBB4 CYP3A4 CYP3A5 ALDH3A1 PPARG ART4	1.48e-05	126	198	8	CID005743034
Drug	BP-4,5-oxide	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4 SLC6A7	1.50e-05	61	198	6	CID000037786
Drug	AC1L1SX8	CYP3A7 ESS2 CYP3A4 CYP3A5	1.54e-05	18	198	4	CID000060278
Drug	zonisamide	CYP3A7 CYP3A4 CYP3A5 SCN3A SCN9A CA5A	1.64e-05	62	198	6	CID000005734
Drug	ciprofibrate	CYP3A4 CYP3A5 ACP2 RYR1 SCD NFKB1 UGT1A6 APOB PPARG	1.87e-05	170	198	9	CID000002763
Drug	4-hydroxycyclophosphamide	CYP3A4 CYP3A5 ALDH3A1 PBRM1 XRCC6	1.88e-05	38	198	5	CID000099735
Drug	rabeprazole	CYP3A7 CYP3A4 CYP3A5 LCT	1.94e-05	19	198	4	CID000005029
Drug	DCNB	ESS2 CYP3A4 CYP3A5 SCN9A UGT1A6 GSTM2 GSTM4	1.96e-05	95	198	7	CID000007443
Drug	Azumoleno	RYR1 RYR2 SLC18A1	2.21e-05	7	198	3	CID000056259
Drug	quercetin	CYP3A7 CYP3A4 CYP3A5 HSPH1 PHKA2 ACSM3 CSNK1G1 HSPA4 NPR1 MMP28 UGT1A6 TPTE2 APOB TMPO ATP2B1	2.25e-05	482	198	15	CID005280343
Drug	phenytoin	CYP3A7 CYP3A4 CYP3A5 RYR1 RYR2 NFKB1 SCN2A SCN3A SCN9A QKI	2.32e-05	219	198	10	CID000001775
Drug	3-methoxymorphinan	CYP3A4 CYP3A5 SCN2A ART4	2.41e-05	20	198	4	CID000001671
Drug	pregnenolone-16 alpha-carbonitrile	CYP3A7 CYP3A4 CYP3A5 SCD UGT1A6 PPARG	2.57e-05	67	198	6	CID000015032
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SETD1B NACA KAT2A NFKB1 BRD1 ZHX2 YJU2 TMPO BUB3	2.70e-05	178	198	9	6276_DN
Drug	oxidized glutathione	CYP3A5 CKM DHDH NFKB1 HSPA4 NPR1 MMP28 GSTM2 GSTM4 SLC6A7	3.15e-05	227	198	10	CID000000975
Drug	3-keto-LCA	CYP3A4 CYP3A5 DHDH	3.51e-05	8	198	3	CID000159623
Drug	amodiaquine quinoneimine	CYP3A4 GSTM2 GSTM4	3.51e-05	8	198	3	ctd:C094705
Drug	NSC406942	HSPH1 NCAPG2 RYR1 RYR2 ME3 ACSM3 DHDH CSNK1G1 HSPA4 COL11A1 POLE2 APOB LCT PBRM1 LRBA ATP2B1	3.75e-05	565	198	16	CID000001115
Drug	chrysin	CYP3A4 CYP3A5 DHDH NFKB1 ATN1 UGT1A6 PPARG	3.99e-05	106	198	7	CID005281607
Drug	DNCB	ESS2 CYP3A4 CYP3A5 DHDH SCN9A HSPA4 UGT1A6 GSTM2 GSTM4	4.31e-05	189	198	9	CID000000006
Drug	AC1L1JAF	CYP3A5 HSPH1 HSPA4 PPARG PBRM1	4.36e-05	45	198	5	CID000004952
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	JAK2 TBC1D4 PSME4 CSNK1G1 USP15 IPO7 CLOCK BAZ1A TMPO	4.49e-05	190	198	9	2619_DN
Drug	stilbene oxide	CYP3A5 DHDH SCN9A GSTM2 GSTM4 PBRM1	4.54e-05	74	198	6	CID000028649
Drug	Glucocorticoids	CYP3A7 CYP3A4 CYP3A5 PPARG GSTM2	4.85e-05	46	198	5	ctd:D005938
Drug	PD138142-15	CYP3A4 CYP3A5 APOB	5.24e-05	9	198	3	CID003025787
Drug	S 840	CYP3A7 CYP3A4 CYP3A5	5.24e-05	9	198	3	CID000096338
Drug	phenethyl isothiocyanate	CYP3A4 CYP3A5 HSPH1 NEK9 NCAPG2 SCD NFKB1 REEP5 HSPA4 UGT1A6 POLE2 LARS1 TMPO	5.29e-05	401	198	13	ctd:C058305
Drug	C14802	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	5.39e-05	47	198	5	CID011954053
Drug	MW 1	RYR1 RYR2 PSME4 IRF8 LCT PIAS4 TPX2 HTT	5.46e-05	151	198	8	CID000073965
Drug	2,4,5,2',5'-pentachlorobiphenyl	TEX2 ITGAD NCAPG2 RYR1 ME3 TNRC18 TBC1D4 PTPRS SCN1A SCN2A SFXN2 TDRD6 COL11A1 CALB2 MMP28 UGT1A6 POLE2 TSPEAR PRSS23 TTLL7 PBRM1 ART4 BAZ1A PLXNC1 TPX2 NEIL3 LRBA KAT14	5.46e-05	1441	198	28	ctd:C009828
Drug	Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	MYO1D NEK9 ME3 JAK2 ACSM3 TBC1D4 QKI TRMO TEX14	5.50e-05	195	198	9	4577_UP
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HT_HG-U133A	KCNIP1 NEK9 RYR2 JAK2 ACSM3 ATN1 APOB PBRM1 CNGB3	5.72e-05	196	198	9	4591_UP
Drug	Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; HL60; HT_HG-U133A	CYP3A5 RAP1GAP2 SCN1A PRSS23 TRAF4 TIAM1 CNGB3 GAN EPHA1	5.95e-05	197	198	9	2404_UP
Drug	C14800	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	5.98e-05	48	198	5	CID011954051
Drug	5,5-dimethyl-1-pyrroline-N-oxide	CYP3A5 NCAPG2 RYR1 DHDH TMPO	5.98e-05	48	198	5	CID000001774
Drug	bromobenzene-3,4-oxide	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	6.61e-05	49	198	5	CID000108121
Drug	ss,ss-carotene	CYP3A7 CYP3A4 CYP3A5 NFKB1 IRF8 APOB PPARG GSTM2 GSTM4	6.95e-05	201	198	9	CID000000573
Drug	lamotrigine	CYP3A4 RYR1 RYR2 SCN2A SCN3A SCN9A UGT1A6	7.09e-05	116	198	7	CID000003878
Drug	bromobenzene-2,3-oxide	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	7.29e-05	50	198	5	CID003036760
Drug	1,1-dichloroethylene epoxide	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	7.29e-05	50	198	5	CID000119521
Drug	4-hydroxymidazolam	CYP3A7 CYP3A4 CYP3A5	7.43e-05	10	198	3	CID000124449
Drug	4-hydroxymidazolam	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C042940
Drug	norverapamil	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C016904
Drug	5,6-dihydro-2H-pyran-2-one	CYP3A4 CYP3A5	7.52e-05	2	198	2	CID000520660
Drug	notopterol	CYP3A4 CYP3A5	7.52e-05	2	198	2	CID005320227
Drug	N-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C114289
Drug	5,5-diethylhydantoin	CYP3A5 EPHA1	7.52e-05	2	198	2	CID000021600
Drug	Maoba	ACSM3 LCT	7.52e-05	2	198	2	CID000476290
Drug	6 beta-hydroxytestosterone	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C025591
Drug	CQA 206-291	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C059483
Drug	fructus schizandrae, radix ginseng, radix ophiopogonis drug combination	CYP3A4 CYP3A5	7.52e-05	2	198	2	ctd:C009252
Drug	phenobarbital	CYP3A7 ERBB4 CYP3A4 CYP3A5 NFKB1 ALDH3A1 CAD UGT1A6 APOB GSTM2 GSTM4 PBRM1	7.91e-05	360	198	12	CID000004763
Drug	naphthalene epoxide	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	8.03e-05	51	198	5	CID000108063
Drug	2',3'-dideoxyadenosine	ADSL PEX19 AMPD1 NPR1 ART4 LRBA	8.11e-05	82	198	6	CID000020039
Drug	lidocaine	CYP3A4 CYP3A5 RYR1 RYR2 PHKA2 SCN3A SCN9A LCT	8.20e-05	160	198	8	CID000003676
Drug	Sodium	SCN2A SCN3A SCN9A NPR1 PPARG SLC18A1	9.28e-05	84	198	6	ctd:D012964
Drug	clofibrate	CYP3A7 CYP3A4 CYP3A5 SCD NFKB1 ALDH3A1 UGT1A6 APOB PPARG GSTM2 GSTM4	9.34e-05	311	198	11	CID000002796
Drug	1,2-dichlorobenzene	CYP3A4 CYP3A5 TMEFF2 DHDH	9.65e-05	28	198	4	CID000007239
Drug	PCB 66	CYP3A5 RYR1 RYR2	1.02e-04	11	198	3	CID000036185
Drug	Troleandomycin	CYP3A7 CYP3A4 CYP3A5	1.02e-04	11	198	3	ctd:D014217
Drug	Ticalopride	CYP3A7 CYP3A4 CYP3A5	1.02e-04	11	198	3	CID000216236
Drug	dichloroacetaldehyde	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	1.06e-04	54	198	5	CID000006576
Drug	9,12,15-octadecatrienoic acid	CYP3A4 SCD ABCD4 HSPA4 AMPD1 APOB PPARG LCT	1.11e-04	167	198	8	CID000000860
Drug	cyfluthrin	CYP3A4 SCN2A SCN3A HYDIN	1.11e-04	29	198	4	ctd:C052570
Drug	chloroacetyl chloride	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	1.16e-04	55	198	5	CID000006577
Drug	bepridil	CYP3A4 RYR1 RYR2 CKM SCN3A SCN9A ATP2B1	1.19e-04	126	198	7	CID000002351
Drug	Lys-Asp	CYP3A4 DMAP1 POLE2 TMPO	1.27e-04	30	198	4	CID003294435
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1B NACA NFKB1 ZHX2 YJU2 TMPO ZFHX3 BUB3	1.30e-04	171	198	8	6879_DN
Drug	Ertiprotafib	CYP3A4 CYP3A5 PPARG	1.35e-04	12	198	3	CID000157049
Drug	desethylamodiaquine	CYP3A4 GSTM2 GSTM4	1.35e-04	12	198	3	ctd:C047386
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1B JAK2 BRD1 TRMO ZHX2 TRAF4 YJU2 TMPO	1.36e-04	172	198	8	6993_DN
Drug	AC1NSAUM	RYR1 TRAF4 EPHA2 XRCC6 EPHA1	1.37e-04	57	198	5	CID005357474
Drug	tiadenol	CYP3A5 DHDH SCD GSTM2 GSTM4	1.37e-04	57	198	5	CID000023403
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B PEG3 NACA PALMD DHX35 TRMO YJU2 TMPO	1.41e-04	173	198	8	4665_DN
Drug	Gsts	CYP3A7 CYP3A4 CYP3A5 SCN9A GSTM2 GSTM4 TRAF4 PBRM1	1.41e-04	173	198	8	CID000128079
Drug	pioglitazone	CYP3A7 CYP3A4 CYP3A5 RYR1 RYR2 TBC1D4 SCD NFKB1 SCN2A APOB PPARG	1.41e-04	326	198	11	CID000004829
Drug	tocopherol	CYP3A4 CYP3A5 TBC1D4 APOB PPARG CDH17	1.45e-04	91	198	6	CID000014986
Drug	M-HN	RYR1 RYR2 CKM EPHA1	1.45e-04	31	198	4	CID000015450
Drug	4'-HPPH	CYP3A4 CYP3A5 NKRF UGT1A6	1.45e-04	31	198	4	CID000017732
Drug	bromoacetaldehyde	CYP3A7 CYP3A4 CYP3A5 GSTM2 GSTM4	1.49e-04	58	198	5	CID000105131
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	SETD1B NFKB1 BRD1 TRMO ZHX2 BAZ1A TMPO ZFHX3	1.53e-04	175	198	8	1058_DN
Drug	p-nitroanisole	PDS5B CYP3A7 CYP3A4 CYP3A5 UGT1A6 PBRM1	1.54e-04	92	198	6	CID000007485
Drug	perfluorohexanesulfonic acid	CYP3A7 CYP3A4 CYP3A5 PEG3 ACSM3 CALB2 PPARG GSTM4	1.59e-04	176	198	8	ctd:C471071
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1B DHX35 ATN1 TRMO ZHX2 YJU2 TMPO ZFHX3	1.59e-04	176	198	8	5976_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	JAK2 BRD1 QKI ZHX2 YJU2 BAZ1A TMPO ZFHX3	1.65e-04	177	198	8	7550_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	RAP1GAP2 ZNF202 PALMD DHX35 TRMO YJU2 TMPO ZFHX3	1.72e-04	178	198	8	4436_DN
Drug	bergaptol	CYP3A4 CYP3A5 GAN	1.74e-04	13	198	3	CID005280371
Drug	carbamazepine	CYP3A7 CYP3A4 CYP3A5 SCN2A SCN3A SCN9A TSPEAR APOB	1.78e-04	179	198	8	CID000002554
Disease	anxiety disorder (implicated_via_orthology)	CYP3A5 SCN1A SCN2A SCN3A SCN9A	2.60e-07	22	191	5	DOID:2030 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	3.47e-07	10	191	4	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	3.47e-07	10	191	4	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	8.09e-07	12	191	4	DOID:0060170 (implicated_via_orthology)
Disease	Colorectal Carcinoma	PEG3 ABCA8 PTPRS VPS13A ABCD4 ADAMTS18 QKI IQUB AMPD1 CAD TSPEAR APOB PPARG LIG3 OSBP TIAM1 TPX2 EPHA1	8.16e-07	702	191	18	C0009402
Disease	tacrolimus measurement	CYP3A7 CYP3A4 CYP3A5	1.06e-06	4	191	3	EFO_0008458
Disease	haptoglobin measurement	IST1 CALB2 ZFHX3 HYDIN	9.34e-06	21	191	4	EFO_0004640
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A SCN9A	2.18e-05	9	191	3	C3502809
Disease	Achromatopsia 3	COL11A1 CNGB3	4.17e-05	2	191	2	C1849792
Disease	Early Infantile Epileptic Encephalopathy 6	SCN1A SCN9A	4.17e-05	2	191	2	C4551549
Disease	cocaine use	SCN1A HSPA4 CLOCK	4.24e-05	11	191	3	C3496069
Disease	DNA repair protein RAD51 homolog 4 measurement	CYP3A7 CYP3A4 TEX14	4.24e-05	11	191	3	EFO_0801531
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A SCN9A	7.28e-05	13	191	3	C0751122
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	1.25e-04	3	191	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	1.25e-04	3	191	2	DOID:8545 (implicated_via_orthology)
Disease	reticulocyte measurement	MYO1D IQGAP2 IST1 ITGAD MIDEAS EHD4 NFKB1 VPS13A QKI HSPA4 MMP28 FLVCR1 PPARG ZNF800 BAZ1A BRD4 TPX2 ATP2B1	1.80e-04	1053	191	18	EFO_0010700
Disease	metabolonic lactone sulfate measurement	CYP3A7 CYP3A4 CYP3A5	2.40e-04	19	191	3	EFO_0800659
Disease	estrone conjugate measurement	CYP3A7 CYP3A4	2.48e-04	4	191	2	EFO_0007971
Disease	ascending aortic diameter	PCSK1 KCNIP1 RYR2 USP15 ATP2B1 HYDIN	3.11e-04	140	191	6	EFO_0021787
Disease	tauro-beta-muricholate measurement	CYP3A7 CYP3A4	4.12e-04	5	191	2	EFO_0800213
Disease	Warburton Anyane Yeboa syndrome	BUB3 CEP57	4.12e-04	5	191	2	C2931286
Disease	glyco-beta-muricholate measurement	CYP3A7 CYP3A4	4.12e-04	5	191	2	EFO_0800569
Disease	Mosaic variegated aneuploidy syndrome 1	BUB3 CEP57	4.12e-04	5	191	2	C1850343
Disease	Brugada syndrome (implicated_via_orthology)	GSTM2 GSTM4	4.12e-04	5	191	2	DOID:0050451 (implicated_via_orthology)
Disease	reticulocyte count	MYO1D IQGAP2 IST1 ITGAD MIDEAS EHD4 NFKB1 VPS13A QKI HSPA4 MMP28 FLVCR1 PPARG ZHX2 ZNF800 BAZ1A ATP2B1	4.80e-04	1045	191	17	EFO_0007986
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	NEB RYR1	6.15e-04	6	191	2	C1854678
Disease	response to antineoplastic agent, response to doxorubicin	ME3 PRSS23	6.15e-04	6	191	2	GO_0097327, GO_1902520
Disease	dehydroisoandrosterone sulfate DHEA-S measurement	CYP3A7 CYP3A4	6.15e-04	6	191	2	EFO_0021119
Disease	androstenediol (3beta,17beta) monosulfate (1) measurement	CYP3A7 CYP3A4	6.15e-04	6	191	2	EFO_0800294
Disease	Schizophrenia	ERBB4 ESS2 CYP3A4 CYP3A5 CMYA5 SLC30A3 ALDH3A1 BRD1 QKI CLOCK GSTM2 PBRM1 SLC18A1 SH3PXD2A FUT8	6.68e-04	883	191	15	C0036341
Disease	mean reticulocyte volume	PDS5B IQGAP2 KAT2A NEB ME3 JAK2 TBC1D4 NFKB1 VPS13A HSPA4 CAD ZHX2 BRD4 TPX2	7.50e-04	799	191	14	EFO_0010701
Disease	Mood Disorders	NFKB1 VPS13A HSPA4 PPARG CLOCK HTT	8.15e-04	168	191	6	C0525045
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	8.57e-04	7	191	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	8.57e-04	7	191	2	C0751057
Disease	Polycystic kidney disease, type 2	PPARG BRD4	8.57e-04	7	191	2	C2751306
Disease	X-24574 measurement	CYP3A7 CYP3A4	8.57e-04	7	191	2	EFO_0800897
Disease	mean corpuscular hemoglobin concentration	PDS5B SETD1B IQGAP2 NEB MIDEAS ME3 TBC1D4 NFKB1 VPS13A SFXN2 IQCJ-SCHIP1 ATN1 ZNF800 TRAF4 BAZ1A BRD4 CEP57	8.91e-04	1105	191	17	EFO_0004528
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	SLC30A3 APOB ZFHX3 ATP2B1	1.06e-03	69	191	4	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	urinary metabolite measurement	CYP3A7 CYP3A4 CYP3A5 C4orf33 NAALAD2 GSTM2 CYP4Z2P	1.13e-03	245	191	7	EFO_0005116
Disease	Early Childhood Epilepsy, Myoclonic	SCN1A SCN9A	1.14e-03	8	191	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	SCN1A SCN9A	1.14e-03	8	191	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	SCN1A SCN9A	1.14e-03	8	191	2	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	SCN1A SCN9A	1.14e-03	8	191	2	C0751120
Disease	pantothenate measurement	SLC30A3 CAD	1.14e-03	8	191	2	EFO_0021034
Disease	Myoclonic Encephalopathy	SCN1A SCN9A	1.14e-03	8	191	2	C0438414
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	PPARG BRD4	1.14e-03	8	191	2	C0887850
Disease	Myoclonic Absence Epilepsy	SCN1A SCN9A	1.14e-03	8	191	2	C0393703
Disease	apolipoprotein B measurement	IST1 MIDEAS ABCA8 CSNK1G1 UGT1A6 APOB PPARG GSTM2 SLC18A1 ZFHX3 HYDIN HTT	1.35e-03	663	191	12	EFO_0004615
Disease	asparaginase-induced acute pancreatitis	NEB ADAMTS18	1.46e-03	9	191	2	EFO_1001507
Disease	asthma, sex interaction measurement	ERBB4 RAP1GAP2	1.46e-03	9	191	2	EFO_0008343, MONDO_0004979
Disease	Febrile Convulsions	SCN1A SCN2A	1.46e-03	9	191	2	C0009952
Disease	Polycystic Kidney, Autosomal Dominant	PPARG BRD4	1.46e-03	9	191	2	C0085413
Disease	Myoclonic Epilepsy	SCN1A SCN9A	1.46e-03	9	191	2	C0014550
Disease	androstenediol (3beta,17beta) disulfate (1) measurement	CYP3A7 CYP3A4	1.46e-03	9	191	2	EFO_0800278
Disease	Schizophrenia and related disorders	CYP3A5 FUT8	1.46e-03	9	191	2	C0809983
Disease	Thyroid Gland Follicular Adenoma	PRDM2 PPARG BRD4	1.50e-03	35	191	3	C0151468
Disease	Thyroid Neoplasm	PRDM2 PPARG BRD4	1.76e-03	37	191	3	C0040136
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	CYP3A7 CYP3A4	1.81e-03	10	191	2	EFO_0022090
Disease	Epilepsy, Myoclonic, Infantile	SCN1A SCN9A	1.81e-03	10	191	2	C0917800
Disease	5alpha-androstan-3beta,17alpha-diol disulfate measurement	CYP3A7 CYP3A4	1.81e-03	10	191	2	EFO_0800289
Disease	X-21607 measurement	MIDEAS CYP4Z2P	2.21e-03	11	191	2	EFO_0800819
Disease	X-21796 measurement	UGT1A6 GSTM2	2.21e-03	11	191	2	EFO_0800825
Disease	androstenediol (3beta,17beta) monosulfate (2) measurement	CYP3A7 CYP3A4	2.21e-03	11	191	2	EFO_0800295
Disease	Myoclonic Astatic Epilepsy	SCN1A SCN9A	2.21e-03	11	191	2	C0393702
Disease	Congenital myopathy (disorder)	NEB RYR1	2.64e-03	12	191	2	C0270960
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	CYP3A7 CYP3A4	2.64e-03	12	191	2	EFO_0800291
Disease	Intellectual Disability	ADSL SCN1A SCN3A QKI ATN1 AGO1 BRD4 FUT8 HTT	2.65e-03	447	191	9	C3714756
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement	IQGAP2 LEMD3 CLOCK	2.72e-03	43	191	3	EFO_0007788, EFO_0008343
Disease	lymphocyte:monocyte ratio	ACP2 EHD4 CSNK1G1 IRF8 DOCK10 PIAS4 TPX2	2.82e-03	288	191	7	EFO_0600088
Disease	obesity (implicated_via_orthology)	PCSK1 CAPN8 GSTM2 GSTM4 LPIN3 ZFHX3	2.85e-03	215	191	6	DOID:9970 (implicated_via_orthology)
Disease	Thyroid carcinoma	PRDM2 PPARG BRD4	2.91e-03	44	191	3	C0549473
Disease	Common variable immunodeficiency	NFKB1 LRBA	3.10e-03	13	191	2	cv:C0009447
Disease	hematologic cancer (implicated_via_orthology)	JAK2 PIAS4	3.10e-03	13	191	2	DOID:2531 (implicated_via_orthology)
Disease	undecenoylcarnitine (C11:1) measurement	SLC16A9 CYP4Z2P	3.10e-03	13	191	2	EFO_0800588
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	CYP3A7 CYP3A4	3.10e-03	13	191	2	EFO_0800293
Disease	5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement	CYP3A7 CYP3A4	3.10e-03	13	191	2	EFO_0800284
Disease	free androgen index	CYP3A7 CYP3A4 ABCA8 QKI SLC16A9 UGT1A6 PPARG GSTM2	3.15e-03	374	191	8	EFO_0007005
Disease	Colonic Neoplasms	CKM PARP4 NFKB1 PPARG BRD4	3.17e-03	152	191	5	C0009375
Disease	Manganese Poisoning	ATP13A2 HTT	3.60e-03	14	191	2	C0677050
Disease	X-21470 measurement	CYP3A7 CYP3A4	3.60e-03	14	191	2	EFO_0800817
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	CYP3A7 CYP3A4	3.60e-03	14	191	2	EFO_0800283
Disease	Amyotrophic Lateral Sclerosis, Familial	CALB2 TIAM1 OTOG	3.73e-03	48	191	3	C4551993
Disease	Amyotrophic Lateral Sclerosis, Sporadic	CALB2 TIAM1 OTOG	3.73e-03	48	191	3	C1862941
Disease	Malignant tumor of colon	CKM PARP4 NFKB1 PPARG BRD4	3.84e-03	159	191	5	C0007102
Disease	neutrophil count	CYP3A5 EHD4 JAK2 ADSL CSNK1G1 SFXN2 COL11A1 IPO7 FLVCR1 IRF8 MAGI3 TEX14 LCT GSTM2 SLC18A1 LRBA HYDIN HTT	3.90e-03	1382	191	18	EFO_0004833
Disease	lung adenocarcinoma (is_implicated_in)	ERBB4 JAK2 ZFHX3	3.95e-03	49	191	3	DOID:3910 (is_implicated_in)
Disease	apolipoprotein B to apolipoprotein A1 ratio	ABCA8 APOB GSTM2	3.95e-03	49	191	3	EFO_0021897
Disease	Generalized hypotonia	ATN1 AGO1	4.14e-03	15	191	2	C1858120
Disease	MMR-related febrile seizures	SCN1A SCN2A	4.14e-03	15	191	2	EFO_0006519
Disease	lysophosphatidylcholine 14:0 measurement	SLC30A3 CAD	4.14e-03	15	191	2	EFO_0010356
Disease	amenorrhea, response to antineoplastic agent	VPS50 APOB	4.14e-03	15	191	2	EFO_0010269, GO_0097327
Disease	16a-hydroxy DHEA 3-sulfate measurement	CYP3A7 CYP3A4	4.14e-03	15	191	2	EFO_0800301
Disease	alopecia areata	SLC16A9 MAGI3 PLXNC1	4.18e-03	50	191	3	EFO_0004192
Disease	AMYOTROPHIC LATERAL SCLEROSIS 1	CALB2 TIAM1 OTOG	4.18e-03	50	191	3	C1862939
Disease	pulse pressure measurement	TEX2 SUCLA2 NEK9 IQCJ-SCHIP1 BRD1 PTCD3 COL11A1 CALB2 PPARG LIG3 PBRM1 PLXNC1 ZFHX3 ATP2B1 HYDIN XRCC6 CDH17 NIN	4.20e-03	1392	191	18	EFO_0005763
Disease	basophil count	RAP1GAP2 RYR1 JAK2 SCD HYAL3 NFKB1 CSNK1G1 CA5A NAALAD2	4.40e-03	483	191	9	EFO_0005090
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	SLC30A3 APOB ATP2B1	4.43e-03	51	191	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	X-21410 measurement	CYP3A7 CYP3A4	4.71e-03	16	191	2	EFO_0800813
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	4.71e-03	16	191	2	C0393706
Disease	andro steroid monosulfate C19H28O6S (1) measurement	CYP3A7 CYP3A4	4.71e-03	16	191	2	EFO_0800305

Protein segments in the cluster

Peptide	Gene	Start	Entry
EAKEVLKPYENRQPY	C5orf63	46	A6NC05
PKKENPIVLLSDFYY	ZNF280B	276	Q86YH2
GHKESYPVKEFEVYP	CYP4Z2P	56	Q8N1L4
DYIYEEQIKTKPPKA	ERICH6	306	Q7L0X2
PKAEDEYVNEPLYLN	ERBB4	1196	Q15303
LKPYVDLQAYEDPAQ	EPHA1	596	P21709
PPVYYKFIEKSAEEL	BRD1	136	O95696
SNDSEPKYYPIAVLL	AVIL	751	O75366
KDKRSYEALYPVPQH	C4orf33	141	Q8N1A6
PVDAVKLNLPDYYKI	BRD4	86	O60885
KKKDSIDPYIYTPFG	CYP3A5	421	P20815
ATIIPQYLDKDLYPV	ALDH3A1	151	P30838
PLPAQEDYYSHLKKE	ATN1	1171	P54259
DVYHYEVDIKPDKCP	AGO1	51	Q9UL18
YVVYPSDKPFLNSDL	CEP57	36	Q86XR8
EYLDPSPEVQKKKYA	BUB3	206	O43684
VYPVPDLLVIADKYD	POLE2	471	P56282
YVYPNEAAVSKDEPK	AMPD1	216	P23109
ISEFYDLKKPPANLY	CAPN8	211	A6NHC0
REQVIYPLKEVYPDS	ABCD4	471	O14678
IPKIDVYLYEVDIKP	AGO3	41	Q9H9G7
VYLYEVDIKPDKCPR	AGO3	46	Q9H9G7
IITYKDPDNPEYLEF	NPR1	311	P16066
YINEKHYKKVPEPEA	ATP2B1	491	P20020
DEPKQAGQYKYPDKL	ADAMTS18	496	Q8TE60
IQVPDYYDIIKKPIA	BAZ1A	1461	Q9NRL2
ENDKEYQEYLKRPPE	RAMAC	21	Q9BTL3
YAPEAPYTSPDKLKD	PDS5B	91	Q9NTI5
QLQEKLYVPVKEYPD	QKI	81	Q96PU8
LPQDKEYYKVKEPGE	JAK2	1001	O60674
PVKKSEAPDYYEVIR	KAT2A	756	Q92830
YKEDGVPVPELYNKI	KIR2DL5A	61	Q8N109
YLKNTYNKPKLSEPE	LEMD3	436	Q9Y2U8
KIAPEDLPDKYSIYN	SLC16A9	201	Q7RTY1
IEDIYANIPDLPKSY	PALMD	136	Q9NP74
EKSSLQPKDIYPYSD	LPIN3	191	Q9BQK8
INSYPKYFQKDIAEP	PTCD3	121	Q96EY7
ELFQKLPSKVQYPDY	PBRM1	206	Q86U86
DEIYYFRKPIVPQKE	PBRM1	1286	Q86U86
QEKYLKYEQVPNSDP	MAGEB1	251	P43366
EVYLKSKTLYEDKPP	MAGI3	706	Q5TCQ9
YGIYKQDLPALEEKP	HSPA4	181	P34932
PLEYKYKNGASPVLE	NEIL3	106	Q8TAT5
SEEDYYTPQKVDVPK	NEK9	516	Q8TD19
ESYPYGSPQEKSLDK	NCKAP5L	611	Q9HCH0
YEKNKLNYTLPQDVP	NRAP	516	Q86VF7
PAEIKDYSPYFKTIE	KRT14	156	P02533
RIKEYLDQLPDFPYK	LAPTM4A	136	Q15012
AKEYIDPETKKHIPY	CSNK1G1	191	Q9HCP0
YGIYKQDLPSLDEKP	HSPH1	181	Q92598
KKNKDNIDPYIYTPF	CYP3A4	421	P08684
YKEYEDKPTSPPNEE	COL11A1	386	P12107
YKEDGVPVPELYNKI	KIR2DL5B	61	Q8NHK3
EVKSYYKAIRDLPPL	PLXNC1	1481	O60486
VKNYEYKKPEERSPL	IPO7	156	O95373
PYKVYRIVPEEEQKC	IRF8	106	Q02556
KEPRYTPVSIYEEKL	KAT14	456	Q9H8E8
YDPDFEKLKPEYLQA	GSTM2	116	P28161
PDSYTKKFEHRIYPI	GXYLT2	161	A0PJZ3
PVNNINVDKDKPYLY	LRBA	241	P50851
LKEEYNDPPIYVTEN	LCT	1736	P09848
KDKPVYDELFYTLSP	EHD4	446	Q9H223
FSSKYVPKYVPLADV	TMPO	386	P42167
VQKEDPAPYLVYLKS	PRSS37	21	A4D1T9
PYNKYSVLLPLVAKE	NUDT7	36	P0C024
LLDVKNYDPYKPLDI	PARP4	86	Q9UKK3
LKVNKIYYPDFIVPD	LIG3	761	P49916
IYYPDFIVPDPKKAA	LIG3	766	P49916
KATEDGTPYDPYKAL	OSBP	756	P22059
PYENQKIPTKENVYE	PEG3	756	Q9GZU2
KYTYPVLKEDTPRQH	KCNIP1	171	Q9NZI2
NPDPVSYYVIEYKSK	PTPRS	356	Q13332
KYKDPLEYSDVIPQA	ITGAD	261	Q13349
TLYKKDGVPVPELYN	KIR2DL4	61	Q99706
SPVKTYPKDPYQEEE	ACP2	46	P11117
DLPPYKSYEQLKEKL	ITCH	876	Q96J02
DVLYPSLKEITEKYP	PEX19	186	P40855
YDPQLKPLRVSYEAA	CA5A	76	P35218
YYPEGVPDEEQLFKK	ESS2	226	Q96DF8
VFLYPEKDEPTYILN	APOB	141	P04114
KSYPQLLVDEALNPY	ATP13A2	226	Q9NQ11
QLPKYVQGEEKYPKT	CEFIP	101	Q711Q0
FSKLYKVPLDTTEYP	HTT	731	P42858
QYELYLKATPALPEK	HYDIN	4916	Q4G0P3
NPKDLDPKYAYIQVT	DOCK10	1936	Q96BY6
CQKPVDKYIEYDPVI	ARV1	61	Q9H2C2
EVYALLYSDKKDAPP	DMAP1	56	Q9NPF5
IPPKTQDSVYYAKEE	DCDC2C	256	A8MYV0
PDVLEYYKNDGSKKP	GAB4	76	Q2WGN9
DIFYLQSPVPDYIKS	DHX35	246	Q9H5Z1
QLKPLKTYVDPHTYE	EPHA2	581	P29317
YNPPKDDGSTYKIEL	GAN	61	Q9H2C0
YTLIDYNISPDPEKQ	CMYA5	3056	Q8N3K9
VFPDLDPQEQLYKAY	HYAL3	156	O43820
QIAPEYFEKNEPYLE	DENND6A	191	Q8IWF6
LDYYTKPQGLDKEPK	ANKMY2	141	Q8IV38
RKEQEIKESPYSPGY	CAPRIN2	776	Q6IMN6
LQDSPPEEYSYKKSI	FLVCR1	311	Q9Y5Y0
PYYEKINSVPAVDQE	MAMLD1	161	Q13495
PTYYNHPEALKREKA	MIDEAS	156	Q6PJG2
LASYYPEPKDKEAFV	ME3	561	Q16798
YIKTPLFNPEVAKYL	IQUB	571	Q8NA54
QVPEEYLKPYDFIQD	ARSB	246	P15848
PYGVYKKQQKDPSEE	ATE1	481	O95260
IPKAYGSYEELAKDP	DHDH	51	Q9UQ10
LIEIAKNYNVPYEPD	IST1	166	P53990
KKANRPYDEPKLQEY	CALB2	141	P22676
PYDEPKLQEYTQTIL	CALB2	146	P22676
IDRNYEPLKTQPKKY	EPS8	521	Q12929
NKAPPTYDTVLQLEY	CYP3A7	341	P24462
KKNKDNIDPYIYTPF	CYP3A7	421	P24462
VAKDEYGKPLSYPLE	CDH17	311	Q12864
PPDYVDASYSSKAEK	RYR1	2711	P21817
YQYSPEFPLDILKSK	RYR2	1776	Q92736
KSEEFKDPAVPYIYS	CFAP47	1106	Q6ZTR5
KDPAVPYIYSLELEE	CFAP47	1111	Q6ZTR5
TTREEGPNKKYPVLY	CFAP47	2141	Q6ZTR5
TEVSLPKYFYIPEKI	CFAP47	2241	Q6ZTR5
EYSLKPQPQDVVSKY	CEBPZ	191	Q03701
ELYAVPPNKVDEEYK	PHKA2	371	P46019
AIYYKTLKPIAPGEE	PRDM2	121	Q13029
DSYKKVQDPSYAPPK	PARD3	1311	Q8TEW0
QYDPAKPNYISLDKL	MTERF3	376	Q96E29
LLFDQYKIIPPYTDD	OTOG	591	Q6ZRI0
EKYGYLNEQVPKAPT	MMP28	41	Q9H239
PSLLKEAKTKYPNYE	FUT8	411	Q9BYC5
IPYIKKESPLLNDYR	RTL8C	81	A6ZKI3
SDPYVKSYLLPDKQS	SYTL1	301	Q8IYJ3
NKDDYIPYPSIDEVV	RAP1GAP2	81	Q684P5
LQDTIKAKYGELEPY	SFXN2	301	Q96NB2
YKLPNKEILEESYKP	TDRD6	1201	O60522
ADVRLPKPYYDIVKS	TEX14	476	Q8IWB6
EKKDYSVLYVVPGPV	TMEFF2	301	Q9UIK5
KLNYKPEEEYPDLSK	CKM	11	P06732
IPEASPKYKLLYEDV	NIN	1241	Q8N4C6
KTNPEYIYAPLKEIP	NKRF	211	O15226
DYEEPFPVYQKKVID	SCHIP1	76	P0DPB3
PQEYTLLKLKVLEPY	LARS1	261	Q9P2J5
PKIFYPETTDVYDRK	IQGAP2	126	Q13576
YSPDFEKLKPEYLEE	GSTM4	116	Q03013
KGTPLPTYEEAKQYL	PRSS23	71	O95084
NDESIKYPYKEDTIP	PLPP1	41	O14494
YSEKTQLYNKPHEEP	PPARG	116	P37231
LEEEVYPLLKPYESV	ADSL	461	P30566
PSYDSVTKPDKEKYE	SCN9A	1956	Q15858
LKQPSEVELEEYYPA	SIN3B	836	O75182
YDYKFPIEDVKIPCL	SETD1B	1941	Q9UPS6
PLEDLDPYYINKKTF	SCN3A	76	Q9NY46
YPAYISIKAIESPNK	REEP5	66	Q00765
EDYEEPFPVYQKKVI	IQCJ-SCHIP1	151	B3KU38
DPAYLKDPKVCNIRY	MRPS18C	126	Q9Y3D5
VPKGYVAKSPDEAYA	SUCLA2	71	Q9P2R7
VTDEFPYYLRPKKAV	SLC6A7	411	Q99884
PLEDLDPYYINKKTF	SCN1A	76	P35498
NKFPELYKDLDSYPD	ABCA8	756	O94911
EATIKIRPVPEYQKY	AGPS	376	O00116
APYKYPRKVEFIQEL	ACSM3	551	Q53FZ2
TIDPKEPSTYEYVKF	CLOCK	201	O15516
KQFEELYSLLEDPYP	NCAPG2	376	Q86XI2
PPVKESDDKPTEHYY	CNGB3	171	Q9NQW8
PNPEKDTEYTLYKKE	STK31	981	Q9BXU1
TDDPEYDPGYKVKQR	ZNF428	56	Q96B54
KLEDVSKPPAYAYPA	TNRC18	1011	O15417
PIPDKEFVETYIKAY	VPS50	896	Q96JG6
LVDEFKELVYPPDYN	XRCC6	521	P12956
KPEPDILEEEKIYAY	TMEM192	201	Q8IY95
TPVLDIKPYIAEYDS	TRMO	151	Q9BU70
PYPKEDNTLLYEITA	WASHC5	1001	Q12768
KCPEYLDENKKPVYL	VPS13A	936	Q96RL7
ESDPEEENYKVPEYK	VPS13A	1816	Q96RL7
VPQPEEDIYELLYKE	TIAM1	821	Q13009
DSPRKLKYEEPEYDI	SH3PXD2A	546	Q5TCZ1
VKDPPSKYVLYTLAV	SNX21	141	Q969T3
VPLEDLDPYYINKKT	SCN2A	76	Q99250
PPLTEYFLNDKYQEE	USP15	311	Q9Y4E8
IRPDIKDDIYDPTYK	SCD	46	O00767
LDYAKIYPDPELEVQ	TRAF4	61	Q9BUZ4
VLNKYYPPDFDPSKI	YJU2	6	Q9BW85
FVPQKEIVYNKLLPY	PSME4	26	Q14997
LTYFAYLIKAQPDDP	TBC1D4	136	O60343
LYETRYAKKNSEPAP	PIAS4	61	Q8N2W9
YPEALTDPSYKAQIL	CAD	36	P27708
IYFKPQYKAADPIST	SLC30A3	256	Q99726
EQPQPGEKLYKYNEL	ZNF333	301	Q96JL9
VVPQYYKDPKKLCEE	ZHX2	726	Q9Y6X8
TVNPEFYNEPKTKLY	ZGRF1	1451	Q86YA3
EVLLGIPYDPKKYDV	TSSK6	181	Q9BXA6
YPSVDKREYIIKLEP	ZNF800	121	Q2TB10
INVYDGPPLYDDVKV	TPTE2	446	Q6XPS3
GKPEDNEVLKYPYET	TSPEAR	251	Q8WU66
EKYVPSKDLPYIKDS	TOGARAM1	1406	Q9Y4F4
KIYPVPYDQEELKNR	UGT1A6	76	P19224
EPKPEVTYISQKIYD	TEX2	596	Q8IWB9
TLKFTYSEKYPDEAP	RWDD1	51	Q9H446
KDYEDIIPPVEIYSL	WDR35	1056	Q9P2L0
APYKYPLNRKNLEET	ZNF202	451	O95125
RIYPPEDKALLEKYE	TTLL7	456	Q6ZT98
PDYCIDPYKRAQLKA	ZAR1L	56	A6NP61
SLYDPFIVPKVQYKL	ZFHX3	3451	Q15911
YYLRSPPAKEEKLAI	SLC18A1	476	P54219
VTPLKPVDNTYYKEA	TPX2	71	Q9ULW0
QVYEGLKPSDKYEKP	HECTD3	501	Q5T447
SKEPYYVRCIKPNDK	MYO1D	581	O94832
YQLVYKLTKEIPSPD	NAALAD2	461	Q9Y3Q0
VQYFSLKKEVLIPPY	ART4	236	Q93070
KPDVYKSPASDTYIV	NACA	1971	E9PAV3
YPPDSINVDLAKKAY	NEB	926	P20929
PYENFYEALEKLNKP	PCSK1	696	P29120
KSDLETSEPKPFLYY	NFKB1	336	P19838
PFLYYPEIKDKEEVQ	NFKB1	346	P19838