Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity L-glutamate transmembrane transporter activity

SLC1A1 SLC1A2 SLC1A6

1.35e-0552233GO:0005314
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3C RIMBP3 RIMBP3B

1.35e-0552233GO:0030156
GeneOntologyMolecularFunctionglutamate:sodium symporter activity

SLC1A1 SLC1A2 SLC1A6

1.35e-0552233GO:0015501
GeneOntologyMolecularFunctionacid-thiol ligase activity

SUCLA2 DIP2A AASDH ACSM4 ACSL5

2.23e-05312235GO:0016878
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

SUCLA2 DIP2A AASDH ACSM4 ACSL5

8.97e-05412235GO:0016877
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP6V1B1 NDUFS1 ABCB1 SLC22A6 ABCC2 SLC23A1 SLC29A4 ATP6V0E1 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC4A2 SLC34A1 ATP6V0E2 ATP12A

9.74e-0547722316GO:0022804
GeneOntologyMolecularFunctionoxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor

GMPR2 GMPR

1.24e-0422232GO:0046857
GeneOntologyMolecularFunctionGMP reductase activity

GMPR2 GMPR

1.24e-0422232GO:0003920
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN9A SCN10A SLC23A1 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC34A1 ATP12A

1.34e-041712239GO:0015081
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP6V1B1 NDUFS1 SLC23A1 ATP6V0E1 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC4A2 SLC34A1 ATP6V0E2 ATP12A

1.53e-0430122312GO:0022853
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1B1 ZGRF1 KIF1B MCM4 SMC5 DDX5 ABCB1 DDX11 BPTF ABCC2 DDX11L8 DNHD1 ATP6V0E1 ACSM4 ATP6V0E2 MACF1 ATP12A ACSL5

1.95e-0461422318GO:0140657
GeneOntologyMolecularFunction5'-3' DNA helicase activity

ZGRF1 DDX11 DDX11L8

2.12e-04112233GO:0043139
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC23A1 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC34A1

2.93e-04812236GO:0015370
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP6V1B1 AQP7P3 NDUFS1 SLC22A6 SCN9A SCN10A ABCC2 SEC61A1 SLC23A1 ATP6V0E1 TTYH2 GRIA3 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC4A2 SLC34A1 ATP6V0E2 ATP12A

3.44e-0475822320GO:0015318
GeneOntologyMolecularFunction3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

PDE10A PDE11A

3.70e-0432232GO:0004118
GeneOntologyMolecularFunctioncysteine transmembrane transporter activity

SLC1A1 SLC1A2

3.70e-0432232GO:0033229
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC22A6 ABCC2 SLC1A1 SLC1A6

3.76e-04312234GO:0005310
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCB1 SLC22A6 ABCC2 SLC29A4

5.40e-04342234GO:0042910
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC1A1 SLC1A2 SLC1A6

5.66e-04152233GO:0005313
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCB1 SLC22A6 ABCC2 SLC23A1 SLC29A4 GRIA3 SLC1A1 SLC1A2 SLC1A6

5.69e-042082239GO:0005342
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC23A1 SLC1A1 SLC1A2 SLC1A6

6.04e-04352234GO:0005343
GeneOntologyMolecularFunctiontriplex DNA binding

DDX11 DDX11L8

7.34e-0442232GO:0045142
GeneOntologyMolecularFunctionNADPH:quinone reductase activity

TP53I3 CRYZ

7.34e-0442232GO:0003960
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC1A1 SLC1A2 SLC1A6

1.36e-03202233GO:0015172
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V1B1 ABCB1 ABCC2 ATP6V0E1 ATP6V0E2 ATP12A

1.41e-031092236GO:0042626
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCB1 SLC22A6 ABCC2 SLC23A1 SLC25A41 GRIA3 SLC1A1 SLC1A2 SLC1A6 SLC4A2

1.75e-0329322310GO:0008514
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

OCRL PIKFYVE

1.81e-0362232GO:0043813
GeneOntologyMolecularFunctiondihydropyrimidinase activity

DPYSL2 DPYSL3

1.81e-0362232GO:0004157
GeneOntologyMolecularFunctioncalcium ion binding

ACTN2 HEG1 NRXN1 UMODL1 JAG1 SYT5 FAT4 DSG1 PCDHGA11 TTYH2 SYT10 SNED1 CELSR3 MACF1 CDH3 CDH9 CDH16 PROS1

1.94e-0374922318GO:0005509
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC1A1 SLC1A2 SLC1A6

2.06e-03232233GO:0005283
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC23A1 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC34A1

2.21e-031192236GO:0015294
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCB1 SLC22A6 ABCC2 SLC23A1 GRIA3 SLC1A1 SLC1A2 SLC1A6

2.33e-032072238GO:0046943
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V1B1 ATP6V0E1 ATP6V0E2

2.34e-03242233GO:0042625
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V1B1 ATP6V0E1 ATP6V0E2

2.34e-03242233GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V1B1 ATP6V0E1 ATP6V0E2

2.34e-03242233GO:0046961
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

ITGA4 ITGAL NRXN1 PTPRS SDK1 FAT4 SDK2 DSG1 PCDHGA11 TENM4 CELSR3 CDH3 CDH9 CDH16

8.52e-0631322314GO:0098742
GeneOntologyBiologicalProcessL-aspartate import across plasma membrane

SLC1A1 SLC1A2 SLC1A6

2.43e-0562233GO:0140009
GeneOntologyCellularComponentpresynapse

ATP6V1B1 KIF1B ADCY8 NRXN1 SCAMP5 PTPRS SCN10A NGFR SYT5 FKBP1A SLC29A4 DPYSL2 PPFIBP2 APC GRIA3 SLC1A1 SLC1A2 SYT10 SLC1A6 MADD SHANK2 CELSR3 TNN ATP6V0E2 RIMS4 CTSD CDH9

8.80e-0788622227GO:0098793
GeneOntologyCellularComponentaxon

BOC KIF1B ITGA4 ADCY8 NRXN1 PTPRS EIF2B2 SCN9A SCN10A NGFR SYT5 FKBP1A DPYSL2 DPYSL3 APC GRIA3 SLC1A1 SLC1A2 OPA1 MADD SHANK2 TNN HCFC1 CDH9

2.86e-0589122224GO:0030424
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA1 ITGA4 ITGAL NRXN1 TNN TNXB

3.78e-05592226GO:0098636
GeneOntologyCellularComponentcell body

BOC ITGA4 PDE10A ADCY8 BPTF NRXN1 FCGR2A BRS3 PTPRS NGFR SYT5 GNB2 PDE11A DPYSL2 DPYSL3 APC RDH5 GRIA3 SLC1A1 SLC1A2 SHANK2 TNN GRIP2 HCFC1

5.54e-0592922224GO:0044297
GeneOntologyCellularComponentapical plasma membrane

ATP6V1B1 PDZK1 ADCY8 ABCB1 JAG1 ABCC2 SLC23A1 SLC29A4 DSG1 SLC34A3 SLC1A1 SLC4A2 SHANK2 SLC34A1 ATP12A OTOG

6.94e-0548722216GO:0016324
GeneOntologyCellularComponentGMP reductase complex

GMPR2 GMPR

1.12e-0422222GO:1902560
GeneOntologyCellularComponentpresynaptic membrane

ADCY8 NRXN1 PTPRS SCN10A NGFR GRIA3 SLC1A2 SLC1A6 CELSR3 RIMS4 CDH9

1.94e-0427722211GO:0042734
GeneOntologyCellularComponentcell-cell junction

VAPA LAMA1 ITGA4 AQP7P3 ITGAL ABCB1 HEG1 NRXN1 AMOT JAG1 NGFR ABCC2 DSG1 APC PIKFYVE CDH3 CDH9

2.05e-0459122217GO:0005911
GeneOntologyCellularComponentapical part of cell

ATP6V1B1 PDZK1 ADCY8 ABCB1 JAG1 ABCC2 SLC23A1 SLC29A4 FAT4 DSG1 SLC34A3 SLC1A1 SLC4A2 SHANK2 SLC34A1 ATP12A OTOG

2.09e-0459222217GO:0045177
GeneOntologyCellularComponentbrush border membrane

PDZK1 AQP7P3 ABCC2 SLC34A3 SHANK2 SLC34A1

2.56e-04832226GO:0031526
GeneOntologyCellularComponentsite of polarized growth

BOC ITGA4 NRXN1 PTPRS NGFR DPYSL2 DPYSL3 APC FRYL SHANK2

3.92e-0425322210GO:0030427
GeneOntologyCellularComponentglutamatergic synapse

FILIP1 ACTN2 PDE10A ADCY8 DIP2A NRXN1 PTPRS SCN10A APC GRIA3 SLC1A2 SYT10 SLC1A6 TENM4 SHANK2 CELSR3 DROSHA RIMS4 GRIP2 CDH9

4.71e-0481722220GO:0098978
GeneOntologyCellularComponentsomatodendritic compartment

BOC KIF1B ACTN2 ITGA4 PDE10A ADCY8 BPTF DIP2A NRXN1 FCGR2A BRS3 PTPRS NGFR SYT5 PDE11A DPYSL2 APC GRIA3 SLC1A1 SLC1A2 OPA1 SHANK2 TNN GRIP2 HCFC1 CDH9

6.28e-04122822226GO:0036477
GeneOntologyCellularComponenttenascin complex

TNN TNXB

6.64e-0442222GO:0090733
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA1 TNN TNXB

7.20e-04172223GO:0098637
GeneOntologyCellularComponentanchoring junction

VAPA LAMA1 ACTN2 ITGA4 AQP7P3 ITGAL ABCB1 HEG1 NRXN1 AMOT JAG1 SVIL NGFR ABCC2 GNB2 DSG1 APC SLC4A2 PIKFYVE SH3PXD2A CDH3 CDH9

7.44e-0497622222GO:0070161
GeneOntologyCellularComponentCul3-RING ubiquitin ligase complex

KLHL2 KLHL3 KLHL9 DEPDC5

7.61e-04392224GO:0031463
GeneOntologyCellularComponentpresynaptic active zone

ADCY8 NRXN1 PPFIBP2 GRIA3 SHANK2 CELSR3 RIMS4

7.87e-041412227GO:0048786
GeneOntologyCellularComponentdistal axon

BOC ITGA4 NRXN1 PTPRS NGFR FKBP1A DPYSL2 DPYSL3 APC GRIA3 SLC1A1 SHANK2 TNN

8.08e-0443522213GO:0150034
GeneOntologyCellularComponentSec61 translocon complex

SEC61A1 SEC61A2

1.10e-0352222GO:0005784
GeneOntologyCellularComponentbrush border

PDZK1 AQP7P3 ABCC2 SLC23A1 SLC34A3 SHANK2 SLC34A1

1.22e-031522227GO:0005903
GeneOntologyCellularComponentgrowth cone

BOC ITGA4 NRXN1 PTPRS NGFR DPYSL2 DPYSL3 APC SHANK2

1.27e-032452229GO:0030426
GeneOntologyCellularComponentneuron spine

ACTN2 DIP2A FCGR2A NGFR GRIA3 SLC1A1 SLC1A2 SHANK2 GRIP2

1.35e-032472229GO:0044309
GeneOntologyCellularComponentneuron to neuron synapse

ACTN2 ADCY8 NRXN1 PTPRS NGFR DPYSL2 GRIA3 SLC1A1 SHANK2 CELSR3 DROSHA MACF1 GRIP2 CDH9

1.47e-0352322214GO:0098984
GeneOntologyCellularComponentsynaptic membrane

ACTN2 ADCY8 NRXN1 PTPRS SCN10A NGFR GRIA3 SLC1A2 SLC1A6 OPRL1 SHANK2 CELSR3 RIMS4 GRIP2 CDH9

1.49e-0358322215GO:0097060
GeneOntologyCellularComponentcytoplasmic vesicle membrane

VAPA ATP6V1B1 SGSM1 KIF1B UBAP1 ITGAL ADCY8 TMEM184A FCGR2A SCAMP5 PTPRS DIO3 SYT5 SEC61A1 MVB12B ATP6V0E1 DSG1 APC GRIA3 OCRL SLC1A1 SYT10 PIKFYVE ATP6V0E2 CTSD AHNAK2

1.54e-03130722226GO:0030659
GeneOntologyCellularComponenttranslocon complex

SEC61A1 SEC61A2

1.64e-0362222GO:0071256
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V1B1 ATP6V0E1 ATP6V0E2 ATP12A

1.80e-03492224GO:0090533
GeneOntologyCellularComponentvesicle membrane

VAPA ATP6V1B1 SGSM1 KIF1B UBAP1 ITGAL ADCY8 TMEM184A FCGR2A SCAMP5 PTPRS DIO3 SYT5 SEC61A1 MVB12B ATP6V0E1 DSG1 APC GRIA3 OCRL SLC1A1 SYT10 PIKFYVE ATP6V0E2 CTSD AHNAK2

1.86e-03132522226GO:0012506
GeneOntologyCellularComponentphagocytic vesicle membrane

SEC61A1 ATP6V0E1 OCRL PIKFYVE ATP6V0E2

1.92e-03832225GO:0030670
GeneOntologyCellularComponentexocytic vesicle

ATP6V1B1 KIF1B SCAMP5 PTPRS SYT5 DPYSL3 APC SYT10 MADD ATP6V0E2

2.31e-0332022210GO:0070382
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6V1B1 ATP6V0E1 ATP6V0E2 ATP12A

2.76e-03552224GO:0098533
GeneOntologyCellularComponentpostsynapse

FILIP1 KIF1B ACTN2 ADCY8 DIP2A FCGR2A PTPRS EIF2B2 NGFR DPYSL2 APC GRIA3 SLC1A1 SLC1A2 SLC1A6 SHANK2 CELSR3 DROSHA MACF1 GRIP2 CDH9

2.87e-03101822221GO:0098794
GeneOntologyCellularComponentexocytic vesicle membrane

ATP6V1B1 KIF1B SCAMP5 PTPRS SYT5 APC ATP6V0E2

3.08e-031792227GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATP6V1B1 KIF1B SCAMP5 PTPRS SYT5 APC ATP6V0E2

3.08e-031792227GO:0030672
GeneOntologyCellularComponentmanchette

RIMBP3C RIMBP3 RIMBP3B

3.18e-03282223GO:0002177
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6V1B1 ATP6V0E1 ATP6V0E2

3.52e-03292223GO:0033176
GeneOntologyCellularComponentneuronal cell body

BOC ITGA4 PDE10A ADCY8 NRXN1 BRS3 PTPRS NGFR SYT5 PDE11A DPYSL2 APC GRIA3 SLC1A1 SHANK2 TNN GRIP2 HCFC1

3.61e-0383522218GO:0043025
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCC2

3.85e-0392222GO:0046581
DomainFN3

BOC SPEG UMODL1 PTPRS ATF7IP2 RIMBP3C SDK1 SDK2 RIMBP3 SNED1 TNN RIMBP3B TNXB HCFC1

9.41e-0819921814PS50853
DomainFN3_dom

BOC SPEG UMODL1 PTPRS ATF7IP2 RIMBP3C SDK1 SDK2 RIMBP3 SNED1 TNN RIMBP3B TNXB HCFC1

1.73e-0720921814IPR003961
DomainFN3

BOC SPEG UMODL1 PTPRS RIMBP3C SDK1 SDK2 SNED1 TNN RIMBP3B TNXB HCFC1

1.87e-0618521812SM00060
DomainVWC_out

JAG1 VWF MUC19 MUC5B OTOG

2.11e-06192185SM00215
DomainEGF-like_dom

LAMA1 HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1 OTOG

7.67e-0624921813IPR000742
DomainC8

VWF MUC19 MUC5B OTOG

8.31e-06122184PF08742
DomainTIL

VWF MUC19 MUC5B OTOG

8.31e-06122184PF01826
DomainUnchr_dom_Cys-rich

VWF MUC19 MUC5B OTOG

1.19e-05132184IPR014853
DomainC8

VWF MUC19 MUC5B OTOG

1.19e-05132184SM00832
Domain-

KLHL2 KLHL3 KLHL9 KLHL18 HCFC1

1.35e-052721852.130.10.80
DomainTIL_dom

VWF MUC19 MUC5B OTOG

1.65e-05142184IPR002919
DomainEGF

LAMA1 HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1

2.15e-0523521812SM00181
DomainEGF_3

HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1 OTOG

2.15e-0523521812PS50026
DomainASX_HYDROXYL

HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 CELSR3 PROS1

2.24e-051002188PS00010
DomainVWF_type-D

VWF MUC19 MUC5B OTOG

2.94e-05162184IPR001846
DomainVWFD

VWF MUC19 MUC5B OTOG

2.94e-05162184PS51233
DomainVWD

VWF MUC19 MUC5B OTOG

2.94e-05162184SM00216
DomainVWD

VWF MUC19 MUC5B OTOG

2.94e-05162184PF00094
DomainEGF-type_Asp/Asn_hydroxyl_site

HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 CELSR3 PROS1

3.43e-051062188IPR000152
DomainGal_Oxidase_b-propeller

KLHL2 KLHL3 KLHL9 KLHL18 HCFC1

4.37e-05342185IPR015916
DomainEGF_1

LAMA1 HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1

4.78e-0525521812PS00022
DomainNA_DICARBOXYL_SYMP_1

SLC1A1 SLC1A2 SLC1A6

5.30e-0572183PS00713
DomainNA_DICARBOXYL_SYMP_2

SLC1A1 SLC1A2 SLC1A6

5.30e-0572183PS00714
DomainSDF

SLC1A1 SLC1A2 SLC1A6

5.30e-0572183PF00375
Domain-

SLC1A1 SLC1A2 SLC1A6

5.30e-05721831.10.3860.10
DomainNa-dicarboxylate_symporter

SLC1A1 SLC1A2 SLC1A6

5.30e-0572183IPR001991
DomainNa-dicarboxylate_symporter_CS

SLC1A1 SLC1A2 SLC1A6

5.30e-0572183IPR018107
DomainEGF-like_CS

LAMA1 HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1

5.98e-0526121812IPR013032
DomainEGF_2

LAMA1 HEG1 NRXN1 UMODL1 JAG1 FAT4 SNED1 TENM4 CELSR3 TNN TNXB PROS1

6.92e-0526521812PS01186
DomainLAM_G_DOMAIN

LAMA1 NRXN1 FAT4 CELSR3 PROS1

7.59e-05382185PS50025
DomainLaminin_G_2

LAMA1 NRXN1 FAT4 CELSR3 PROS1

9.76e-05402185PF02210
DomainCT

VWF MUC19 MUC5B OTOG

1.12e-04222184SM00041
Domainfn3

BOC SPEG UMODL1 PTPRS SDK1 SDK2 SNED1 TNN TNXB

1.23e-041622189PF00041
DomainVWF_dom

JAG1 VWF MUC19 MUC5B OTOG

1.24e-04422185IPR001007
DomainRFX_DNA_binding

RFX2 RFX3 ARID2

1.25e-0492183PF02257
DomainDNA-bd_RFX

RFX2 RFX3 ARID2

1.25e-0492183IPR003150
DomainRFX_DBD

RFX2 RFX3 ARID2

1.25e-0492183PS51526
DomainSecY_su_dom

SEC61A1 SEC61A2

1.36e-0422182IPR023201
DomainSECY_1

SEC61A1 SEC61A2

1.36e-0422182PS00755
DomainSECY_2

SEC61A1 SEC61A2

1.36e-0422182PS00756
DomainATPase_V0-cplx_e1/e2_su_met

ATP6V0E1 ATP6V0E2

1.36e-0422182IPR017385
Domain-

SEC61A1 SEC61A2

1.36e-04221821.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A1 SEC61A2

1.36e-0422182IPR019561
DomainSecY_CS

SEC61A1 SEC61A2

1.36e-0422182IPR030659
DomainATP_synt_H

ATP6V0E1 ATP6V0E2

1.36e-0422182PF05493
DomainPlug_translocon

SEC61A1 SEC61A2

1.36e-0422182PF10559
DomainATPase_V0-cplx_e1/e2_su

ATP6V0E1 ATP6V0E2

1.36e-0422182IPR008389
DomainSecY

SEC61A1 SEC61A2

1.36e-0422182PF00344
DomainGMPR

GMPR2 GMPR

1.36e-0422182IPR005993
DomainSecY/SEC61-alpha

SEC61A1 SEC61A2

1.36e-0422182IPR002208
DomainLamG

LAMA1 NRXN1 FAT4 CELSR3 PROS1

1.55e-04442185SM00282
DomainCys_knot_C

VWF MUC19 MUC5B OTOG

1.88e-04252184IPR006207
DomainCTCK_2

VWF MUC19 MUC5B OTOG

1.88e-04252184PS01225
DomainCadherin_CS

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

2.92e-041092187IPR020894
DomainCADHERIN_1

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

3.64e-041132187PS00232
DomainCadherin

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

3.64e-041132187PF00028
DomainCADHERIN_2

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

3.84e-041142187PS50268
Domain-

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

3.84e-0411421872.60.40.60
DomainAMP-binding

DIP2A AASDH ACSM4 ACSL5

3.90e-04302184PF00501
DomainAMP-dep_Synth/Lig

DIP2A AASDH ACSM4 ACSL5

3.90e-04302184IPR000873
DomainNa/Pi_transpt

SLC34A3 SLC34A1

4.04e-0432182IPR003841
DomainRFX1_trans_act

RFX2 RFX3

4.04e-0432182IPR007668
DomainRFX1_trans_act

RFX2 RFX3

4.04e-0432182PF04589
DomainNa_Pi_cotrans

SLC34A3 SLC34A1

4.04e-0432182PF02690
DomainCA

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

4.04e-041152187SM00112
DomainCadherin-like

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

4.26e-041162187IPR015919
DomainCadherin

FAT4 DSG1 PCDHGA11 CELSR3 CDH3 CDH9 CDH16

4.73e-041182187IPR002126
DomainLaminin_G

LAMA1 NRXN1 FAT4 CELSR3 PROS1

5.73e-04582185IPR001791
DomainEGF_CA

HEG1 UMODL1 JAG1 FAT4 SNED1 CELSR3 PROS1

5.77e-041222187SM00179
DomainGal_Oxase/kelch_b-propeller

KLHL2 KLHL3 KLHL9 KLHL18 HCFC1

6.21e-04592185IPR011043
DomainEGF-like_Ca-bd_dom

HEG1 UMODL1 JAG1 FAT4 SNED1 CELSR3 PROS1

6.36e-041242187IPR001881
DomainIg-like_fold

BOC SPEG FCGR2A UMODL1 PTPRS RIMBP3C SDK1 SDK2 TRIM2 SLC4A2 RIMBP3 SNED1 SHANK2 SIGLEC6 TNN FCRL4 RIMBP3B TNXB HCFC1

6.43e-0470621819IPR013783
DomainEGF

HEG1 NRXN1 JAG1 SNED1 CELSR3 TNXB PROS1

7.00e-041262187PF00008
DomainIMPDH

GMPR2 GMPR

8.01e-0442182PF00478
DomainCortactin-binding_p2_N

FILIP1 FILIP1L

8.01e-0442182IPR019131
DomainIMP_DH_GMPRt

GMPR2 GMPR

8.01e-0442182IPR001093
DomainIMP_DH_GMP_RED

GMPR2 GMPR

8.01e-0442182PS00487
DomainIMP_DH/GMP_Rdtase_CS

GMPR2 GMPR

8.01e-0442182IPR015875
DomainCortBP2

FILIP1 FILIP1L

8.01e-0442182PF09727
DomainEGF_Ca-bd_CS

HEG1 UMODL1 JAG1 FAT4 SNED1 PROS1

9.65e-04972186IPR018097
DomainVWC

JAG1 VWF MUC19 MUC5B

9.76e-04382184SM00214
DomainEGF_CA

HEG1 UMODL1 JAG1 FAT4 SNED1 PROS1

1.07e-03992186PS01187
DomainCTCK_1

VWF MUC19 MUC5B

1.12e-03182183PS01185
DomainUMA

UBAP1 MVB12B

1.33e-0352182PS51497
DomainUMA

UBAP1 MVB12B

1.33e-0352182IPR023340
DomainDUF4371

FAM200A THAP12

1.33e-0352182IPR025398
DomainDUF4371

FAM200A THAP12

1.33e-0352182PF14291
DomainKelch_1

KLHL2 KLHL3 KLHL9 KLHL18 HCFC1

1.35e-03702185PF01344
DomainKelch_1

KLHL2 KLHL3 KLHL9 KLHL18 HCFC1

1.35e-03702185IPR006652
DomainBTB-kelch_protein

KLHL2 KLHL3 KLHL9 KLHL18

1.56e-03432184IPR017096
DomainHydantoinase/dihydroPyrase

DPYSL2 DPYSL3

1.97e-0362182IPR011778
Domain-

BOC SPEG FCGR2A UMODL1 PTPRS RIMBP3C SDK1 SDK2 TRIM2 RIMBP3 SNED1 SIGLEC6 TNN FCRL4 RIMBP3B TNXB HCFC1

2.06e-03663218172.60.40.10
DomainGrowth_fac_rcpt_

LAMA1 UMODL1 JAG1 FAT4 TNN TNXB PROS1

2.41e-031562187IPR009030
DomainQuin_OxRdtase/zeta-crystal_CS

TP53I3 CRYZ

2.74e-0372182IPR002364
DomainQOR_ZETA_CRYSTAL

TP53I3 CRYZ

2.74e-0372182PS01162
DomainGAF

PDE10A PDE11A

2.74e-0372182PF01590
DomainCadherin_C

DSG1 CDH3 CDH9

2.98e-03252183PF01049
DomainCadherin_cytoplasmic-dom

DSG1 CDH3 CDH9

2.98e-03252183IPR000233
DomainAMP-binding_CS

AASDH ACSM4 ACSL5

3.34e-03262183IPR020845
DomainEGF_CA

HEG1 UMODL1 JAG1 FAT4 PROS1

3.35e-03862185PF07645
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

ATP6V1B1 ABCB1 SLC22A6 ABCC2 ATP6V0E1 SLC34A3 SLC1A1 SLC4A2 SLC34A1

3.39e-08571779M39812
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 KIAA0232 SPEG KIF1B SMC5 ZNF644 VIRMA OPA1 MADD YEATS2 TENM4 MACF1 UBE3C SON PLCE1

8.01e-084072251512693553
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CPAMD8 MBTPS1 SGSM1 KIAA0232 KIF1B FOXN3 PDE10A SUCLA2 FARP2 TTC8 BPTF KLHL9 TMEM184A PTPRS DOCK6 RIC1 DPYSL2 PPFIBP2 FRYL ST3GAL3 SLC1A1 OPRL1 YEATS2 SHANK2 SH3PXD2A MACF1 UBE3C PNPLA7 CPNE7

1.35e-0714892252928611215
Pubmed

Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins.

LAMA1 NFYA C3 RFX2

2.10e-07922548661125
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A MGAT4B SPEG ANKHD1 DIP2A HEG1 PTPRS TMEM132A DOCK6 RIC1 MVB12B FRYL MLLT10 MADD C6orf132 PIKFYVE SHANK2 CELSR3 OGDHL DEPDC5 UBE3C HAS3 HCFC1 AHNAK2

2.59e-0711052252435748872
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FILIP1 CPAMD8 HEG1 ZNF644 YEATS2 OGDHL MACF1 GRIP2

3.80e-07103225810574462
Pubmed

Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter.

SLC1A1 SLC1A2 SLC1A6

1.06e-06422539379843
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3C RIMBP3 RIMBP3B

1.06e-064225319091768
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ZGRF1 KIF1B DDX5 DDX11 ANAPC1 ZNF644 TAF9 APC AASDH GSR RIMBP3 PIKFYVE YEATS2 DROSHA ARID2 MACF1

1.69e-065882251638580884
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KIF1B ACTN2 MDH1 SUCLA2 NDUFS1 DDX5 DIP2A SCAMP5 PTPRS AMOT SVIL GNB2 DPYSL2 DPYSL3 VWF APC CBR1 SLC1A2 VIRMA OPA1 MADD TENM4 SHANK2 OGDHL MACF1 SNRPN

2.28e-0614312252637142655
Pubmed

Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients.

ABCB1 ABCC2 UGT1A1

2.65e-065225319771428
Pubmed

Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells.

SLC1A1 SLC1A2 SLC1A6

2.65e-06522539129177
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3C RIMBP3 RIMBP3B

2.65e-065225317855024
Pubmed

Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study.

ABCB1 SLC22A6 ABCC2

2.65e-065225319400747
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

KLHL2 PDZK1 ANKHD1 FCHO1 NDUFS1 DDX5 DIP2A TMEM184A IFT80 GNB2 FKBP1A ARHGEF28 ST3GAL3 MADD SLC4A2 SEC61A2 TAMM41 DROSHA CTSD FILIP1L

2.90e-069252252028986522
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

KIF1B SMC5 ANKHD1 NDUFS1 BPTF SVIL DPYSL2 VWF APC SERPINB2 MACF1 AHNAK2

4.58e-063602251233111431
Pubmed

Identification and characterization of a seven transmembrane hormone receptor using differential display.

NFYA C3 RFX2

5.27e-06622539169125
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC16 MUC5B

5.27e-066225319110483
Pubmed

Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study.

ABCB1 ABCC2 UGT1A1

5.27e-066225316791115
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SMC5 ANKHD1 ANAPC1 AMOT DPYSL2 DSG1 APC OCRL CBR1 SH3PXD2A RRN3 SERPINB2 MACF1 PRR11 NNT SON AHNAK2

5.69e-067242251736232890
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

VAPA UBAP1 NDUFS1 FARP2 KLHL9 ANAPC1 DPYSL2 NEBL APC MADD SLC4A2 PIKFYVE YEATS2 WBP4 UBE3C PRR11 HCFC1

6.69e-067332251734672954
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

VAPA ACTN2 PDE10A NDUFS1 DDX5 ABCB1 DDX11 BPTF NRXN1 UMODL1 SCN9A KRT20 ABCC2 SEC61A1 PCDHGA11 GRIA3 GSR SEC61A2 SHANK2 SH3PXD2A TNN OGDHL MACF1 ATP12A SNRPN

8.12e-0614422252535575683
Pubmed

Integrated pharmacogenetic prediction of irinotecan pharmacokinetics and toxicity in patients with advanced non-small cell lung cancer.

ABCB1 ABCC2 UGT1A1

9.17e-067225318221820
Pubmed

Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin.

ITGA4 ITGAL VWF

1.46e-05822538562500
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

ANAPC1 TMEM132A DOCK6 SDK1 MUC16 MUC5B CBR1 OTOG

1.62e-05170225823314748
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HECW1 KIAA0232 SMC5 PASK NRXN1 AMOT TENM4 MACF1 GRIP2

1.75e-05225225912168954
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCB1 ABCC2 SLC29A4 SLC1A1 SLC1A2

2.20e-0552225526590417
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TET2 NRXN1 TMEM132A IFT80 MADD CELSR3 MACF1

2.33e-05130225712421765
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

ATP6V1B1 ACTN2 MDH1 ABCB1 GGTLC3 PTPRS TMEM132A C3 GNB2 FAT4 MUC5B CBR1 GSR CRYZ CTSD TNXB CDH16 PROS1 CPNE7 PCOLCE

2.41e-0510702252023533145
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MGAT4B ANKHD1 FARP2 DIP2A SEC61A1 DDX11L8 RIC1 ARHGEF28 APC MADD POLR3A SLC4A2 DROSHA HCFC1 PLCE1

2.49e-056502251538777146
Pubmed

Irinotecan pathway genotype analysis to predict pharmacokinetics.

ABCB1 ABCC2 UGT1A1

3.10e-0510225312960109
Pubmed

Regulation of the glutamate transporter EAAT2 by PIKfyve.

SLC1A2 PIKFYVE

4.17e-052225219910676
Pubmed

Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin.

ABCB1 ABCC2

4.17e-052225221864659
Pubmed

Molecular cloning of two glutamate transporter subtypes from mouse brain.

SLC1A1 SLC1A2

4.17e-05222527766664
Pubmed

CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.

SCN9A DPYSL2

4.17e-052225223836888
Pubmed

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

ABCB1 ABCC2

4.17e-052225216611851
Pubmed

Architecture of cell-cell adhesion mediated by sidekicks.

SDK1 SDK2

4.17e-052225230150416
Pubmed

The NFY transcription factor inhibits von Willebrand factor promoter activation in non-endothelial cells through recruitment of histone deacetylases.

NFYA VWF

4.17e-052225212511565
Pubmed

Concurrence of novel mutations causing Gilbert's and Dubin-Johnson syndrome with poor clinical outcomes in a Han Chinese family.

ABCC2 UGT1A1

4.17e-052225236274106
Pubmed

Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter localization and function.

SLC1A1 SLC1A2

4.17e-052225215187084
Pubmed

Undetectable histone O-GlcNAcylation in mammalian cells.

TET2 HCFC1

4.17e-052225226075789
Pubmed

PSMD5 Inactivation Promotes 26S Proteasome Assembly during Colorectal Tumor Progression.

PSMD5 APC

4.17e-052225229716915
Pubmed

Genetic factors influencing severe atazanavir-associated hyperbilirubinemia in a population with low UDP-glucuronosyltransferase 1A1*28 allele frequency.

ABCB1 UGT1A1

4.17e-052225220504240
Pubmed

Studies on the structure of the mouse CBF-A gene and properties of a truncated CBF-A isoform generated from an alternatively spliced RNA.

NFYA RUNX2

4.17e-05222527509302
Pubmed

Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124.

ABCB1 UGT1A1

4.17e-052225219349543
Pubmed

Role of the putative PKC phosphorylation sites of the type IIc sodium-dependent phosphate transporter in parathyroid hormone regulation.

SLC34A3 SLC34A1

4.17e-052225230895530
Pubmed

Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.

ABCB1 ABCC2

4.17e-052225216788565
Pubmed

Prevalence, correlates and clinical usefulness of antibodies to RNA polymerase III in systemic sclerosis: a cross-sectional analysis of data from an Australian cohort.

POLR3D POLR3A

4.17e-052225222189167
Pubmed

Deferasirox-induced serious adverse reaction in a pediatric patient: pharmacokinetic and pharmacogenetic analysis.

ABCC2 UGT1A1

4.17e-052225226403473
Pubmed

Proximal tubular handling of phosphate: A molecular perspective.

SLC34A3 SLC34A1

4.17e-052225216955105
Pubmed

Association between FCGR2A rs1801274 and MUC5B rs35705950 variations and pneumonia susceptibility.

FCGR2A MUC5B

4.17e-052225232252656
Pubmed

PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein.

PDZK1 ABCC2

4.17e-052225210496535
Pubmed

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

SCN9A SCN10A

4.17e-052225216111501
Pubmed

Molecular cloning and characterization of a novel form of the human vacuolar H+-ATPase e-subunit: an essential proton pump component.

ATP6V0E1 ATP6V0E2

4.17e-052225217350184
Pubmed

Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein.

ABCC2 UGT1A1

4.17e-052225217185998
Pubmed

Digenic Heterozygous Mutations in SLC34A3 and SLC34A1 Cause Dominant Hypophosphatemic Rickets with Hypercalciuria.

SLC34A3 SLC34A1

4.17e-052225232311027
Pubmed

Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators.

GMPR2 GMPR

4.17e-0522252218932
Pubmed

DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis.

DDX5 APC

4.17e-052225232817263
Pubmed

Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development.

SLC34A3 SLC34A1

4.17e-052225219570882
Pubmed

Identification and targeting of a unique NaV1.7 domain driving chronic pain.

SCN9A DPYSL2

4.17e-052225237498871
Pubmed

Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.

JAG1 APC

4.17e-052225219325125
Pubmed

Association between the polymorphisms in the ATP-binding cassette genes ABCB1 and ABCC2 and the risk of drug-resistant epilepsy in a Chinese Han population.

ABCB1 ABCC2

4.17e-052225227886333
Pubmed

Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina.

SDK1 SDK2

4.17e-052225212230981
Pubmed

Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.

ABCB1 ABCC2

4.17e-052225223717663
Pubmed

Type IIc sodium-dependent phosphate transporter regulates calcium metabolism.

SLC34A3 SLC34A1

4.17e-052225219056871
Pubmed

Relative contributions of alpha4 and alphaL integrins to IL-4-induced leukocyte rolling and adhesion.

ITGA4 ITGAL

4.17e-052225215726833
Pubmed

The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.

SLC1A1 SLC1A2

4.17e-052225212614333
Pubmed

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.

PDE10A APC

4.17e-052225224704829
Pubmed

Detection of circulating tumor cells in peripheral blood of colorectal cancer patients without distant organ metastases.

KRT20 GUCY2C

4.17e-052225223150200
Pubmed

NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties.

GMPR2 GMPR

4.17e-052225212009299
Pubmed

The role of P-glycoprotein in intestinal tumorigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice.

ABCB1 APC

4.17e-052225212807720
Pubmed

Molecular basis of sidekick-mediated cell-cell adhesion and specificity.

SDK1 SDK2

4.17e-052225227644106
Pubmed

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition.

ABCB1 ABCC2

4.17e-052225221039333
Pubmed

C3d fragment of complement interacts with laminin and binds to basement membranes of glomerulus and trophoblast.

LAMA1 C3

4.17e-05222523488995
Pubmed

Role of APC-mediated MDR-1/CLCX-1 signaling pathway in ovarian tumors.

ABCB1 APC

4.17e-052225229921377
Pubmed

Antigen-specific lymphocyte sequestration in lymphoid organs: lack of essential roles for alphaL and alpha4 integrin-dependent adhesion or Galphai protein-coupled receptor signaling.

ITGA4 ITGAL

4.17e-052225215240673
Pubmed

ABCC2 haplotype is not associated with drug-resistant epilepsy.

ABCB1 ABCC2

4.17e-052225218416940
Pubmed

Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy.

SDK1 SDK2

4.17e-052225215213259
Pubmed

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.

APC GUCY2C

4.17e-052225217681179
Pubmed

Canonical TGF-β Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression.

DPYSL2 TGIF1

4.17e-052225229695415
Pubmed

Effects of UGT1A1*6, UGT1A1*28, and ABCB1-3435C>T polymorphisms on irinotecan induced toxicity in Chinese cancer patients.

ABCB1 UGT1A1

4.17e-052225226857783
Pubmed

Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin.

ITGA4 VWF

4.17e-05222529079671
Pubmed

Definition of the critical domains required for homophilic targeting of mouse sidekick molecules.

SDK1 SDK2

4.17e-052225215703275
Pubmed

[Study on the relationship between the expression of adhesion molecules and the invasiveness of acute myeloid leukemia cells].

ITGA4 ITGAL

4.17e-052225215622747
Pubmed

The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits.

SLC1A1 SLC1A6

4.17e-052225217360917
Pubmed

p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation.

DDX5 RUNX2

4.17e-052225217960593
Pubmed

The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.

ABCB1 ABCC2

4.17e-052225216959944
Pubmed

Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.

DPYSL2 DPYSL3

4.17e-052225222826151
Pubmed

Segment-specific expression of sodium-phosphate cotransporters NaPi-IIa and -IIc and interacting proteins in mouse renal proximal tubules.

SLC34A3 SLC34A1

4.17e-052225215007650
Pubmed

Relationship of hepatic functional imaging to irinotecan pharmacokinetics and genetic parameters of drug elimination.

ABCB1 UGT1A1

4.17e-052225216896007
Pubmed

Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.

APC GUCY2C

4.17e-052225215825168
Pubmed

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.

JAG1 APC

4.17e-052225219935714
Pubmed

cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11.

PDE10A PDE11A

4.17e-052225216330539
Pubmed

Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.

APC GUCY2C

4.17e-052225219351847
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A1 SEC61A2

4.17e-052225218480044
Pubmed

Response of Npt2a knockout mice to dietary calcium and phosphorus.

SLC34A3 SLC34A1

4.17e-052225228448530
Pubmed

The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.

C3 MUC5B

4.17e-052225229565179
Pubmed

Induction of DEAD Box helicase 5 in early adipogenesis is regulated by Ten-eleven translocation 2.

TET2 DDX5

4.17e-052225232169654
Pubmed

Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice.

SLC34A3 SLC34A1

4.17e-052225223515284
Pubmed

The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis.

TAL1 VWF

4.17e-05222528118024
Pubmed

RNA binding protein DDX5 directs tuft cell specification and function to regulate microbial repertoire and disease susceptibility in the intestine.

DDX5 APC

4.17e-052225234853057
InteractionC2CD4B interactions

KIAA0232 PASK SVIL FAT4 APC MACF1

8.31e-06442226int:C2CD4B
InteractionADAMTS13 interactions

KIAA0232 PASK FAT4 VWF MACF1

8.45e-06262225int:ADAMTS13
GeneFamilyFibronectin type III domain containing

BOC PTPRS ATF7IP2 SDK1 SDK2 SNED1 TNN TNXB

5.73e-051601508555
GeneFamilyKelch like|BTB domain containing

KLHL2 KLHL3 KLHL9 KLHL18

3.99e-04421504617
GeneFamilyCD molecules|Mucins

MUC19 MUC16 MUC5B

6.67e-04211503648
GeneFamilyV-type ATPases

ATP6V1B1 ATP6V0E1 ATP6V0E2

8.78e-04231503415
GeneFamilyAcyl-CoA synthetase family

AASDH ACSM4 ACSL5

1.27e-0326150340
GeneFamilySolute carriers

SLC22A6 SLC23A1 SLC29A4 SLC25A41 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC4A2 SLC34A1

1.72e-0339515010752
GeneFamilyRegulatory factor X family

RFX2 RFX3

1.85e-03815021153
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

BOC SPEG PTPRS SDK1 SDK2 SIGLEC6

2.26e-031611506593
GeneFamilyESCRT-I

UBAP1 MVB12B

2.37e-03915021116
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

CPAMD8 C3

2.37e-03915021234
GeneFamilySodium voltage-gated channel alpha subunits

SCN9A SCN10A

2.37e-03915021203
CoexpressionZHONG_PFC_C3_MICROGLIA

MBTPS1 KIF1B ACTN2 FCHO1 NRXN1 TMEM132A SYT5 SDK1 DPYSL2 DPYSL3 CCDC184 SDK2 TRIM2 GRIA3 OPA1 POLR3A TENM4 SHANK2 SH3PXD2A ATP6V0E2

8.92e-0948822420M39104
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

TET2 BPTF KLHL18 RIC1 FRYL USP37 YEATS2 MACF1 DEPDC5 HCFC1

3.66e-0618022410M8239
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 LAMA1 NRXN1 SCN9A SDK1 FAT4 MUC5B TENM4 OTOG PLCE1

3.59e-08184225102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 LAMA1 NRXN1 SCN9A SDK1 FAT4 MUC5B TENM4 OTOG PLCE1

3.59e-08184225102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 LAMA1 NRXN1 SCN9A SDK1 FAT4 MUC5B TENM4 OTOG PLCE1

3.59e-0818422510ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA8 SCAMP5 PTPRS NGFR SDK1 GRIA3 RUNX2 TENM4 GRIP2

2.54e-071732259ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA8 SCAMP5 PTPRS NGFR SDK1 GRIA3 RUNX2 TENM4 GRIP2

2.54e-07173225919a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB1 SCN10A C3 MUC16 C6orf132 ATP6V0E2 TNXB AHNAK2 PCOLCE

2.93e-0717622598e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB1 SCN10A C3 MUC16 C6orf132 ATP6V0E2 TNXB AHNAK2 PCOLCE

2.93e-071762259ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFS1 TRIM2 CASP1 GSR SLC4A2 UGT1A1 FRRS1 GUCY2C FILIP1L

2.93e-0717622591dd54bfaa58541de51e5a8328651d390833bd480
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPAS3 ACTN2 TTC8 SDK1 SDK2 NEBL SNED1 TNXB PCOLCE

3.55e-07180225908ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPAS3 ACTN2 TTC8 SDK1 SDK2 NEBL SNED1 TNXB PCOLCE

3.55e-0718022599b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HECW1 PDZK1 ABCB1 SLC22A6 ABCC2 ARHGEF28 SLC1A1 SLC34A1 CDH9

3.72e-0718122596980ea624151da32b7f537f263e40fcb87a02e81
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRERF1 BOC PDE10A PTPRS FOXC2 GRIA3 SNED1 TENM4 TNXB

4.08e-0718322597eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC SPEG ACTN2 PTPRS SDK1 SNED1 TENM4 TNXB PCOLCE

5.84e-07191225914057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

STRA8 LAMA1 SEC11C ARHGEF28 SLC1A2 C6orf132 SHANK2 HAS3 CDH3

6.37e-071932259979980369d2dbee9dc4770d72b93037abd7786eb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 KIF1B DDX5 NRXN1 GMPR FRYL MADD MACF1 SON

6.94e-0719522597796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 KIF1B DDX5 NRXN1 GMPR FRYL MADD MACF1 SON

6.94e-0719522593e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3 CDH16

7.25e-0719622590a34a0009f479384f1994c6f977f942699a132c8
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE10A SDK1 TRIM2 ARHGEF28 MUC16 MUC5B RUNX2 ATP12A CDK6

8.58e-072002259b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE10A TMEM184A TRIM2 ARHGEF28 PPFIBP2 MUC16 MUC5B SHANK2 ATP12A

8.58e-07200225985c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCHO1 ABCB1 KRT20 SYT5 SLC29A4 ST3GAL3 VWA7 PNPLA7

1.53e-061592258709b57f992a29878cc899d760d144d36cb5cb280
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVIL C3 SLC25A41 BTBD18 SLC1A6 TNXB CDH9 PCOLCE

2.02e-061652258f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA0232 LAMA1 SEC11C NRXN1 SCAMP5 SDK1 MVB12B ATP6V0E2

2.87e-06173225823e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC11C NRXN1 SCN9A NGFR DPYSL3 CELSR3 ATP6V0E2 GRIP2

3.55e-061782258a9ba4089413b1c55d667ce836b6972ca572ee2b8
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC11C NRXN1 SCN9A NGFR DPYSL3 CELSR3 ATP6V0E2 GRIP2

3.55e-06178225813dfd28a80889c2dacdc65b94a41bb9762dc409d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 NRXN1 SYT5 SLC29A4 PDE11A PCDHGA11 RFX2 CELSR3

3.55e-06178225830ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGSM1 ABCB1 SYT5 RIMBP3C CCDC184 ARHGEF28 SLC1A2 OGDHL

3.70e-061792258228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGSM1 SEC11C ABCB1 SYT5 RIMBP3C DPYSL3 CCDC184 ARHGEF28

3.70e-061792258b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDZK1 ABCB1 SLC22A6 ABCC2 ARHGEF28 SLC1A1 SHANK2 CDH9

3.86e-061802258358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDZK1 ABCB1 SLC22A6 ABCC2 ARHGEF28 SLC1A1 SHANK2 CDH9

3.86e-061802258864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPAS3 SDK1 FAT4 SDK2 SYT10 GRIP2 CDH9 CPNE7

4.18e-0618222587dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 MDH1 SVIL RIMBP3C GTF2A1L SYT10 MRPL18 FILIP1L

4.18e-06182225837547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Lypd1_(CA1_Principal_cells_(Anterior))|Hippocampus / BrainAtlas - Mouse McCarroll V32

ATP6V1B1 DIO3 FKBP1A PDE11A RIMBP3 GUCY2C

4.30e-0684225652d167614afa9b056f2934142d3250fe5e70e806
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ITGA4 DIO3 FKBP1A ARHGEF28 RUNX2 TNXB CPNE7

4.47e-061302257c70fb77324916d220d842a575558a8245c276599
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ABCB1 NRXN1 SCN9A SYT5 CCDC184 ARHGEF28 CELSR3 ATP6V0E2

4.72e-061852258512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GMPR SDK1 FAT4 CCDC184 SYT10 ACSM4 GRIP2 PLCE1

4.72e-0618522580b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MCM4 ITGA4 IFT80 FRYL RUNX2 ARID2 MACF1 CDK6

4.91e-0618622588571956890fc9894d766ba294a28e376b4aba428
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDZK1 FOXN3 ABCB1 KRT20 ABCC2 SLC23A1 CBR1 SLC1A1

4.91e-061862258bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ATP6V1B1 C3 GMPR FOXC2 TRIM2 MUC16 MUC5B RUNX2

4.91e-061862258ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDZK1 FOXN3 ABCB1 KRT20 ABCC2 SLC23A1 CBR1 SLC1A1

5.11e-0618722589042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA1 ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3 CDH16

5.11e-061872258db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDZK1 SLC22A6 ABCC2 ARHGEF28 SHANK2 OGDHL CDH9 CDH16

5.11e-061872258d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC MCM4 NDUFS1 TRIM2 RDH5 GSR UGT1A1 FRRS1

5.74e-061902258c0ee404d705b0b4f0c6ded4d070ad85eac4b16db
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA4 BPTF HEG1 DPYSL3 SH3PXD2A MACF1 FILIP1L SON

5.74e-061902258d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

SGSM1 NPAS3 KLHL3 DOCK6 TAL1 FOXC2 DPYSL3 TNXB

5.74e-06190225891bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PDZK1 SLC22A6 ABCC2 SDK1 SLC1A1 SLC34A1 CDH9

5.97e-0619122581c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PDZK1 SLC22A6 ABCC2 SDK1 SLC1A1 SLC34A1 CDH9

5.97e-0619122583c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MBTPS1 MCM4 ITGA4 FRYL RUNX2 ARID2 MACF1 CDK6

5.97e-0619122589454f642c3621370fa23640b631301346b300950
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 GMPR SDK2 TTYH2 MADD SEPSECS SH3PXD2A OGDHL

6.20e-0619222585b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 C6orf132 SHANK2 HAS3 CDH3

6.20e-06192225839804d9ddc67c1b41887752df2503389eae44a1a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRERF1 JAG1 NGFR GMPR NEBL RUNX2 SNED1 TGIF1

6.20e-0619222584c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3

6.20e-061922258b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TRERF1 JAG1 NGFR GMPR NEBL RUNX2 SNED1 TGIF1

6.20e-061922258c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

BOC HEG1 NGFR C3 TAL1 CCDC184 SNED1 TENM4

6.44e-061932258194e7fa00a50cc4e026987b715323d125d79594e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HECW1 ZGRF1 MCM4 DDX11 PASK GMPR RUNX2 ATP6V0E2

6.44e-061932258bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3

6.44e-0619322584b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

NPAS3 NRXN1 SCN9A CCDC184 APC GRIP2 SNRPN CDH9

6.69e-061942258b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

NPAS3 NRXN1 SCN9A CCDC184 APC GRIP2 SNRPN CDH9

6.69e-06194225881e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ARHGEF28 SLC1A2 SHANK2 ATP6V0E2 HAS3 CDH3

6.69e-061942258413112ee8df7407fd418d57c2ff11aad3a6ec259
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3

6.69e-061942258c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA1 PDE10A FCGR2A SCN10A ARHGEF28 NEBL MUC19 MUC16

6.95e-06195225819853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA1 PDE10A FCGR2A SCN10A ARHGEF28 NEBL MUC19 MUC16

6.95e-061952258d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPAMD8 SDK1 TRIM2 MUC16 MUC5B TENM4 SHANK2 CDH3

6.95e-061952258e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell(5)_Fibroblast-J_(Lipofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

BOC DDX11 NGFR C3 DPYSL3 GUCY2C TNXB PCOLCE

7.21e-061962258afa29399decd17fda7d63add5039ff778627ccc2
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC11C NRXN1 SCN9A NGFR DPYSL3 SYT10 ATP6V0E2 GRIP2

7.21e-061962258eea354bdaf4c558df6a94ec4f2f817f7073821d9
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA1 SEC11C ADCY8 ARHGEF28 SLC1A2 SHANK2 HAS3 CDH3

7.49e-06197225822b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

FOXN3 TMEM132A C3 DPYSL3 MUC16 MUC5B ATP12A CDK6

7.49e-06197225878ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FOXN3 FAT4 DPYSL3 SDK2 NEBL TENM4 SH3PXD2A MACF1

7.49e-061972258f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FILIP1 ACTN2 PDE10A GMPR FOXC2 CCDC184 GRIP2 FILIP1L

7.77e-061982258f261a37dd07976548b897af86df1d1a0dc069889
ToppCellTracheal-10x3prime_v2-Stromal-Schwann|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL3 NRXN1 PTPRS ZNF644 SCN9A SYT10 YEATS2 ATP6V0E2

8.06e-0619922588dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCellTracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL3 NRXN1 PTPRS ZNF644 SCN9A SYT10 YEATS2 ATP6V0E2

8.06e-061992258a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC11C NRXN1 SCN9A NGFR SYT5 DPYSL3 SYT10 ATP6V0E2

8.06e-06199225847466253069d4b1b8f13ce3210f434e60753b38a
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

BOC NPAS3 PTPRS TRIM2 ARHGEF28 MUC16 MUC5B ATP12A

8.36e-062002258682960e28542a3d6c119047cd0131941932cfdea
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 ITGA4 DDX5 BPTF ZNF644 FRYL MACF1 SON

8.36e-06200225812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GMPR SDK1 FAT4 CCDC184 SYT10 ACSM4 GRIP2 PLCE1

8.36e-062002258501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

GMPR SDK1 FAT4 CCDC184 SYT10 ACSM4 GRIP2 PLCE1

8.36e-062002258d1f36a8232411933b1494168ec912fd0e5246428
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A18 HECW1 SCN9A SCN10A ABCC2 PDE11A ATP12A

9.17e-06145225796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDZK1 RIMBP3C SDK2 SHANK2 ATP12A CPNE7 CDK6

1.36e-051542257ac539c8ca9e1d48b59bff8026775c2147543f3e2
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA8 GMPR2 PDE10A ITGAL NRXN1 SCAMP5 SLC1A2

1.48e-051562257d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZGRF1 PDE11A NEBL MUC16 MUC5B FRRS1 ATP12A

1.54e-051572257c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

ATP6V1B1 NPAS3 SCN9A NGFR PDE11A MUC16 OGDHL

1.74e-051602257d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE10A SDK1 TRIM2 MUC16 MUC5B SHANK2 ATP12A

1.81e-0516122572d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ATP6V1B1 DDX11 NRXN1 TMEM132A DPYSL3 MUC5B ATP12A

1.81e-051612257bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

ATP6V1B1 NPAS3 SCN9A NGFR PDE11A MUC16 OGDHL

1.81e-051612257f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

FARP2 PTPRS SCN9A NGFR RFX3 C6orf132 SIGLEC6

1.81e-05161225751b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A18 HECW1 SCN9A SCN10A ABCC2 PDE11A ATP12A

1.88e-051622257bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HAO1 HEG1 DOCK6 TAL1 VWF SNED1 SERPINB2

1.96e-05163225773c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC C3 FOXC2 TRIM2 NEBL MUC5B SHANK2

1.96e-051632257be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 GMPR MVB12B TRIM2 ARHGEF28 PPFIBP2 OGDHL

2.04e-051642257d847d509bb1791638032ade6755d8164586b5bd5
ToppCell356C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FILIP1 SGSM1 SCAMP5 PTPRS GRIA3 RUNX2 C6orf132

2.04e-051642257fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 UMODL1 SCN10A MVB12B PPFIBP2 SYT10 GRIP2

2.04e-05164225783141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 STRA8 TMEM132A ST3GAL3 SEPSECS EFR3B PLCE1

2.04e-05164225778de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellC_02|World / shred on cell type and cluster

MS4A18 PDZK1 ABCB1 KRT20 ABCC2 CBR1 ACSL5

2.12e-051652257a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Fos_(Deep_layer_pyramidal_cells_(IEG))|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ATP6V1B1 STRA8 CROCC2 DIO3 BTBD18

2.24e-05672255b17d498034ab8280be4991cca1527373d7e43f38
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

SCAMP5 PTPRS SCN9A NGFR RUNX2 TENM4 SIGLEC6

2.29e-051672257bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SCAMP5 PTPRS SCN9A NGFR RUNX2 TENM4 SIGLEC6

2.38e-051682257968405ea56f7d001ef83ff9274610923c3b2d55d
ComputationalNeighborhood of ARL3

ATP6V1B1 PDE10A ABCB1 SLC22A6 NRXN1 AMOT SYT5 KLHL18 FRYL RUNX2 MLLT10 OPRL1 TENM4 GUCY2C WBP4 GRIP2

1.38e-0630413616MORF_ARL3
ComputationalNeighborhood of IL13

ATP6V1B1 SLC22A6 POLR3D NRXN1 JAG1 SYT5 KLHL18 FRYL RUNX2 OPRL1 TENM4 WBP4 GRIP2

8.00e-0623413613MORF_IL13
ComputationalNeighborhood of FOSL1

ATP6V1B1 ABCB1 SLC22A6 NRXN1 PTPRS JAG1 SYT5 GMPR KLHL18 FRYL RUNX2 MLLT10 OPRL1 TENM4 WBP4 DEPDC5 GRIP2

1.38e-0540613617MORF_FOSL1
ComputationalNeighborhood of TFDP2

ATP6V1B1 SLC22A6 POLR3D AMOT SYT5 KLHL18 FRYL RUNX2 MLLT10 OPRL1 WBP4 GRIP2

3.38e-0523013612MORF_TFDP2
ComputationalNeighborhood of IL16

ABCB1 SLC22A6 AMOT SYT5 KLHL18 FRYL RUNX2 MLLT10 OPRL1 TENM4 GUCY2C WBP4

4.92e-0523913612MORF_IL16
ComputationalNeighborhood of MT4

ATP6V1B1 FOXN3 SMC5 FCHO1 DDX11 SLC22A6 POLR3D JAG1 KLHL18 FRYL OPRL1 GRIP2

6.77e-0524713612MORF_MT4
ComputationalNeighborhood of RAP1A

ATP6V1B1 SMC5 SLC22A6 POLR3D JAG1 KLHL18 FRYL OPRL1 GRIP2

6.88e-051401369MORF_RAP1A
ComputationalNeighborhood of BNIP1

SLC22A6 SYT5 KLHL18 FRYL RUNX2 MLLT10 OPRL1 TENM4 WBP4 GRIP2

1.45e-0419013610MORF_BNIP1
ComputationalNeighborhood of NOS2A

ABCB1 SLC22A6 PTPRS SYT5 KLHL18 FRYL RUNX2 MLLT10 OPRL1 TENM4 WBP4 GRIP2

2.86e-0428813612MORF_NOS2A
ComputationalNeighborhood of TNFRSF25

DDX11 SLC22A6 PTPRS JAG1 NGFR SYT5 KLHL18 FRYL TENM4 DEPDC5 GRIP2

5.49e-0426613611MORF_TNFRSF25
ComputationalNeighborhood of BCL2L11

PDE10A SLC22A6 NRXN1 AMOT SYT5 RUNX2 MLLT10 TENM4 GUCY2C

5.81e-041861369MORF_BCL2L11
ComputationalNeighborhood of MAGEA9

PDE10A ABCB1 SLC22A6 PTPRS SYT5 GMPR FRYL RUNX2 MLLT10 TENM4 GUCY2C WBP4 DEPDC5 GRIP2

9.16e-0442313614MORF_MAGEA9
ComputationalNeighborhood of MSH3

ATP6V1B1 SLC22A6 AMOT SYT5 KLHL18 FRYL RUNX2 MLLT10 WBP4 GRIP2

1.02e-0324313610MORF_MSH3
ComputationalGenes in the cancer module 286

MDH1 TP53I3 CBR1 CRYZ

1.17e-03371364MODULE_286
ComputationalNeighborhood of NF1

ATP6V1B1 SLC22A6 SYT5 KLHL18 FRYL OPRL1 WBP4 GRIP2

1.40e-031701368MORF_NF1
ComputationalNeighborhood of PTPRB

PDE10A ABCB1 SLC22A6 NRXN1 AMOT RUNX2 MLLT10 TENM4 GUCY2C WBP4

1.42e-0325413610MORF_PTPRB
Drugfuracin

GMPR2 JAG1 GMPR OPA1 GSR

3.30e-07162215CID000001839
DrugAC1NDU26

TRERF1 MBTPS1 ITGA4 ITGAL FKBP1A

1.90e-06222215CID004631606
DrugOxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A

PDE10A PASK NEBL CASP1 APC OPRL1 CELSR3 SIGLEC6 MRPS11 PLCE1 CDK6

3.27e-06194221112114_UP
DrugBromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A

PTPRS SYT5 C3 FOXC2 TRIM2 APC SEC61A2 SH3PXD2A TNN DEPDC5 AHNAK2

3.98e-06198221111507_UP
Drughydride

ATP6V1B1 PDZK1 GMPR2 MDH1 NDUFS1 C3 GMPR FKBP1A ATP6V0E1 RDH5 CBR1 SLC1A1 SLC1A2 SLC1A6 GSR SLC4A2 CRYZ GUCY2C SLC34A1 ATP6V0E2 OGDHL ATP12A NNT

7.28e-0683522123CID000000783
Drugchloride

BOC ATP6V1B1 PDZK1 MDH1 ADCY8 DDX5 ABCB1 SLC22A6 POLR3D NGFR SLC29A4 CASP1 SLC34A3 OSGEP CBR1 SLC1A1 SLC1A2 SLC1A6 GSR SLC4A2 SEPSECS SHANK2 CELSR3 GUCY2C SLC34A1 THAP12

8.34e-06102922126CID000000312
Drugfluorescein

BOC MBTPS1 ABCB1 SLC22A6 AMOT ABCC2 RDH5 OPA1 TNN

2.37e-051572219CID000016850
DrugSB 203580; Down 200; 1uM; MCF7; HT_HG-U133A

PTPRS SVIL NFYA MED20 ARHGEF28 NEBL SH2D3A DEPDC5 HCFC1 CDK6

2.40e-05197221107061_DN
DrugGelsemine [509-15-9]; Down 200; 12.4uM; PC3; HT_HG-U133A

FOXN3 HEG1 DOCK6 CASP1 APC MLLT10 SLC1A6 SERPINB2 CPNE7 PCOLCE

2.40e-05197221104097_DN
Drugglucoraphanin

TRERF1 CASP1 UGT1A1 CRYZ CDK6

2.43e-05362215CID000656556
Drugsuccinate

MDH1 PDE10A SUCLA2 NDUFS1 ABCB1 SLC22A6 C3 SLC1A1 GSR CRYZ OGDHL CTSD NNT

2.95e-0533922113CID000001110
Drugepoxiconazole

HAO1 ABCB1 NRXN1 SEC61A1 SLC23A1 ATP6V0E1 NEBL SLC1A2 SLC1A6 GSR SHANK2 PNPLA7 CTSD

3.13e-0534122113ctd:C109476
DrugAC1L1CQC

ABCB1 SCN9A SCN10A CBR1 OPRL1 CTSD

4.00e-05652216CID000002012
DrugFusidic Acid

ABCB1 ABCC2 UGT1A1

4.87e-0582213ctd:D005672
Drug2,3-PDCA

GRIA3 SLC1A1 SLC1A2

4.87e-0582213CID000127037
Drugginkgolide A

ABCB1 ABCC2 UGT1A1

4.87e-0582213ctd:C477042
Drugbenznidazole

GMPR2 GMPR GSR FRRS1

5.51e-05222214CID000031593
Drugcaffeic acid phenethyl ester

NFYA NGFR DMRT1 FOXC2 VWF CASP1 RUNX2 SLC1A1 OPA1 GSR SLC4A2 SERPINB2

5.63e-0531122112ctd:C055494
Drugarabinosyladenine

BOC PDZK1 MDH1 PDE10A ADCY8 ABCB1 C3 ABCC2 SLC29A4 VWF APC GRIA3 MLLT10 MADD OPRL1 PIKFYVE GUCY2C NNT THAP12 TNXB

5.79e-0576222120CID000000191
Drugponasterone A

NGFR SLC1A1 SLC1A2 OPRL1 THAP12 CDK6

6.10e-05702216CID000115127
Drugethacrynic acid

KIF1B ADCY8 ABCB1 SLC22A6 SCN9A ABCC2 CBR1 GSR

6.25e-051382218CID000003278
DrugMexiletine

ABCB1 SCN9A SCN10A

7.26e-0592213ctd:D008801
DrugAC1L3M3D

ABCB1 CBR1 GSR SHANK2 TNXB

7.33e-05452215CID000091445
Drug5-Acetamido-5,6-Dihydro-4-Hydroxy-6-Isobutoxy-4h-Pyran-2-Carboxylic Acid

BOC SCN9A C3 DSG1 GRIA3 OPA1

7.74e-05732216CID011963505
Drugnitrofuran

GMPR2 JAG1 GMPR GSR

9.31e-05252214CID000011865
Drugenkephalin-Leu, Ala(2)-melphalan methyl ester-

ABCB1 ABCC2

9.38e-0522212ctd:C040240
Drug3-nitrofluoranthen-6-ol

GMPR2 GMPR

9.38e-0522212CID000146572
Drug3-nitrofluoranthen-9-ol

GMPR2 GMPR

9.38e-0522212CID000146573
Drug3-nitrofluoranthen-8-ol

GMPR2 GMPR

9.38e-0522212CID000146567
Drug1,3,6-trinitropyrene

GMPR2 GMPR

9.38e-0522212CID000053229
DrugAC1L25J4

GMPR2 GMPR

9.38e-0522212CID000041328
Drug2-methylcarbazole

GMPR2 GMPR

9.38e-0522212CID000019290
Drugm-nitrobenzamidine hydrochloride

GMPR2 GMPR

9.38e-0522212CID000165122
Drugbenzoylmesaconine

ABCB1 ABCC2

9.38e-0522212ctd:C085283
Drug2-nitrobenzofuran

GMPR2 GMPR

9.38e-0522212CID000036328
Drug1,3,6,8-tetranitropyrene

GMPR2 GMPR

9.38e-0522212CID000034321
Drugbenzoylaconine

ABCB1 ABCC2

9.38e-0522212ctd:C047307
DrugMethoxychlor

FILIP1 STRA8 KIF1B PSMD5 FOXN3 PASK DIO3 C3 MOS RUNX2 SLC1A2 SLC1A6 GSR OPRL1 UGT1A1 SNRPN

9.91e-0554922116ctd:D008731
DrugN-phthaloyl-DL-glutamic acid

ABCB1 ABCC2 OPA1

1.03e-04102213CID000004804
Drug3,5-dinitroaniline

GMPR2 GMPR FRRS1

1.03e-04102213CID000012068
Drugboldine

ABCC2 SLC4A2 UGT1A1

1.03e-04102213ctd:C011686
DrugRimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A

NPAS3 BRS3 PTPRS JAG1 DOCK6 SH2D3A MLLT10 SEC61A2 CELSR3

1.09e-0419122192955_UP
DrugAC1L1MAZ

GMPR2 GMPR GSR FRRS1

1.09e-04262214CID000031772
Drugnimesulide

MGAT4B SEC11C MCM4 PSMD5 FOXN3 HAO1 GMPR2 ABCB1 FCGR2A SVIL ABCC2 SEC61A1 ATP6V0E1 PPFIBP2 TTYH2 TP53I3 CBR1 GSR MRPL18 SLC34A1 ATP6V0E2 UBE3C PNPLA7 TM2D1 NNT ACSL5

1.14e-04120222126ctd:C012655
Drugcyproconazole

HAO1 ABCB1 ABCC2 SEC61A1 SLC23A1 PDE11A ARHGEF28 ATP6V0E1 NEBL GSR PNPLA7 CTSD

1.17e-0433622112ctd:C093628
DrugIdoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

KIAA0232 HEG1 PTPRS JAG1 C3 DPYSL2 NNT FILIP1L CPNE7

1.18e-0419322191480_UP
DrugAC1L1IBS

GMPR2 JAG1 GMPR GSR

1.27e-04272214CID000004509
DrugBenfotiamine [22457-89-2]; Up 200; 8.6uM; PC3; HT_HG-U133A

HECW1 ITGA4 PASK SYT5 ABCC2 TAL1 FKBP1A DEPDC5 HCFC1

1.27e-0419522194312_UP
DrugMedrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A

MCM4 MVB12B MED20 TRIM2 CASP1 APC MLLT10 SERPINB2 OGDHL

1.27e-0419522193705_DN
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

ATP6V1B1 HECW1 DOCK6 MOS PDE11A ARHGEF28 TNN DEPDC5 AHNAK2

1.32e-0419622194119_UP
Drug(-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A

JAG1 KRT20 C3 PIGO ARHGEF28 CASP1 APC RUNX2 HCFC1

1.32e-0419622193530_UP
DrugDigoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ATP6V1B1 SPEG JAG1 C3 ABCC2 DOCK6 PPFIBP2 APC CDK6

1.32e-0419622193397_DN
DrugMephenytoin [50-12-4]; Up 200; 18.4uM; PC3; HT_HG-U133A

HECW1 FOXN3 PDE10A NEBL SNED1 SIGLEC6 OGDHL FILIP1L CPNE7

1.32e-0419622195801_UP
Drugpyrachlostrobin

BOC RETSAT ABCB1 HEG1 AMOT SVIL C3 ATP6V0E1 TTYH2 VWA7 SLC1A6 SLC4A2 UGT1A1 PNPLA7 NNT CDH9 PROS1 PLCE1 CDK6 PCOLCE

1.34e-0481122120ctd:C513428
Drugcopper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A

SETD1A FCHO1 GMPR TRIM2 APC SLC4A2 SHANK2 HCFC1 CPNE7

1.38e-041972219438_UP
DrugAltretamine [654-05-6]; Up 200; 19uM; PC3; HT_HG-U133A

SETD1A SCAMP5 SCN10A PIGO MVB12B CASP1 APC GRIA3 MLLT10

1.38e-0419722194627_UP
DrugBetaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; PC3; HT_HG-U133A

MBTPS1 POLR3D NFYA PIGO DPYSL3 MLLT10 MADD NNT PCOLCE

1.38e-0419722194608_DN
DrugMedrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A

HEG1 SCN10A DMRT1 NEBL MUC5B RFX3 SNED1 EFR3B CPNE7

1.38e-0419722194727_UP
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A

MBTPS1 SCN10A GMPR PIGO MED20 NEBL CASP1 ATP12A HCFC1

1.38e-0419722195939_DN
Drugsodium

ATP6V1B1 HECW1 PDZK1 MDH1 ADCY8 SLC22A6 SCN9A SCN10A GMPR ABCC2 SLC23A1 SLC29A4 GRIA3 SLC34A3 SLC1A1 SLC1A2 SLC1A6 SLC4A2 CRYZ GUCY2C SLC34A1 ATP12A

1.39e-0494422122CID000000923
Drugdimethylnitramine

GMPR2 FARP2 GMPR

1.41e-04112213CID000020120
Drugcarbanilide

BOC ITGA4 CTSD

1.41e-04112213CID000007595
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

HECW1 PASK HEG1 PTPRS JAG1 ARHGEF28 NEBL SEC61A2 AHNAK2

1.43e-0419822191544_UP
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

SETD1A PTPRS JAG1 ATF7IP2 NEBL RUNX2 SIGLEC6 FILIP1L PLCE1

1.43e-0419822196248_UP
Drug5-deazariboflavin

HAO1 C3 GSR FRRS1

1.47e-04282214CID000159867
Drugerucin

ABCB1 ABCC2 UGT1A1 CRYZ

1.47e-04282214CID000078160
DrugClofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A

PDE10A SCN10A C3 NEBL APC MUC5B EFR3B CDH9 AHNAK2

1.48e-0419922193239_UP
DrugAC1MRR4B

BOC MDH1 NDUFS1 BPTF APC TAMM41 THAP12 ACSL5 PROS1

1.48e-041992219CID003522484
Drugnordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A

SETD1A FCHO1 HEG1 PIGO APC SH3PXD2A HCFC1 CPNE7 CDK6

1.48e-0419922192683_DN
DrugEthamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A

ACTN2 SYT5 MVB12B MLNR RFX2 SLC1A2 OPRL1 SNED1 OGDHL

1.48e-0419922194399_UP
DrugMethylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; PC3; HT_HG-U133A

GMPR PIGO FAT4 MADD SNED1 CELSR3 MRPS11 CPNE7 PLCE1

1.54e-0420022194618_DN
DiseaseSchizophrenia

SETD1A PDZK1 LAMA1 NPAS3 MDH1 NDUFS1 ABCB1 NRXN1 JAG1 NGFR DIO3 APC GRIA3 SLC1A1 SLC1A2 SLC1A6 OPA1 TENM4 SH3PXD2A TNXB

8.18e-0688321520C0036341
Diseaseneurodegenerative disease (implicated_via_orthology)

VAPA FAT4 GRIA3 SLC1A1 SLC1A2 SLC1A6 OGDHL PNPLA7

1.18e-051452158DOID:1289 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

ABCB1 SCAMP5 SCN9A SCN10A SLC1A1 SLC1A6 DEPDC5 ATP12A

2.75e-051632158DOID:1826 (implicated_via_orthology)
DiseaseHepatic fibrosis

FOXN3 SDK1 SDK2 ATP12A CDH3

2.88e-05492155HP_0001395
Diseasehereditary hypophosphatemic rickets with hypercalciuria (is_implicated_in)

SLC34A3 SLC34A1

5.28e-0522152DOID:0050947 (is_implicated_in)
DiseaseCystic Kidney Diseases

IFT80 SEC61A1 FAT4

6.03e-05112153C1691228
DiseaseHereditary Diffuse Gastric Cancer

FILIP1 GMPR2 NDUFS1 KRT20 FAT4 APC SLC1A2 SERPINB2 MRPS11 PLCE1

6.30e-0529321510C1708349
DiseaseStomach Neoplasms

FILIP1 GMPR2 NDUFS1 KRT20 FAT4 APC SLC1A2 SERPINB2 MRPS11 PLCE1

7.05e-0529721510C0038356
DiseaseMalignant neoplasm of stomach

FILIP1 GMPR2 NDUFS1 KRT20 FAT4 APC SLC1A2 SERPINB2 MRPS11 PLCE1

7.66e-0530021510C0024623
DiseaseInflammatory Bowel Diseases

ITGA4 ITGAL MUC19 APC

1.20e-04352154C0021390
DiseaseAutistic Disorder

ITGA4 FARP2 PASK NRXN1 SCAMP5 APC SHANK2 SNRPN CDH9

1.36e-042612159C0004352
DiseasePrimary Erythermalgia

SCN9A SCN10A

1.58e-0432152C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN9A SCN10A

1.58e-0432152C1833661
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX11 DDX11L8

1.58e-0432152DOID:0060535 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease

VAPA BOC TET2 SETD1A SPEG KIF1B NPAS3 SVIL ARHGEF28 NEBL RUNX2 VWA7 SLC1A2 TENM4 SH3PXD2A

1.73e-0468821515EFO_0000341
DiseaseColorectal Carcinoma

BOC TET2 CPAMD8 LAMA1 ADCY8 ABCB1 PTPRS KRT20 ABCC2 PIGO DPYSL2 APC GUCY2C ACSL5 PROS1

2.15e-0470221515C0009402
DiseaseBipolar Disorder

VAPA NPAS3 PDE10A ADCY8 NRXN1 DPYSL2 GRIA3 SLC1A1 SLC1A2 SLC1A6 TENM4 SHANK2

2.15e-0447721512C0005586
DiseaseChromosome 2q37 deletion syndrome

FARP2 PASK

3.14e-0442152C2931817
DiseaseHyperbilirubinemia

ABCC2 UGT1A1

3.14e-0442152C0020433
DiseaseAmyotrophic Lateral Sclerosis, Sporadic

CASP1 GRIA3 CTSD OTOG

4.15e-04482154C1862941
DiseaseAmyotrophic Lateral Sclerosis, Familial

CASP1 GRIA3 CTSD OTOG

4.15e-04482154C4551993
DiseaseIntellectual Disability

SETD1A LAMA1 BPTF NRXN1 SCAMP5 APC ST3GAL3 OSGEP SLC1A2 SHANK2 MACF1

4.73e-0444721511C3714756
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

CASP1 GRIA3 CTSD OTOG

4.85e-04502154C1862939
Diseasebilirubin metabolic disorder (implicated_via_orthology)

ABCC2 UGT1A1

5.21e-0452152DOID:2741 (implicated_via_orthology)
Diseaseage at first sexual intercourse measurement

SPEG SMC5 BPTF NRXN1 SDK1 APC ST3GAL3 VIRMA TENM4 CPNE7

5.41e-0438321510EFO_0009749
Diseaselung non-small cell carcinoma (is_implicated_in)

TET2 ABCB1 ABCC2 RUNX2 UGT1A1 CDK6

5.61e-041392156DOID:3908 (is_implicated_in)
Diseasepulse pressure measurement

TET2 UBAP1 SUCLA2 DDX5 TTC8 DIP2A JAG1 SCN10A IFT80 GNB2 NEBL FRYL SYT10 MADD OPRL1 TGIF1 TENM4 NNT HCFC1 FILIP1L PLCE1 CDK6

5.66e-04139221522EFO_0005763
DiseaseMental Depression

ADCY8 ABCB1 NRXN1 NGFR DPYSL2 GRIA3 SLC1A1 SLC1A2

5.81e-042542158C0011570
DiseaseDegenerative polyarthritis

DPYSL2 TRIM2 RUNX2 OPA1 CTSD

6.06e-04932155C0029408
DiseaseOsteoarthrosis Deformans

DPYSL2 TRIM2 RUNX2 OPA1 CTSD

6.06e-04932155C0086743
DiseaseSquamous cell carcinoma of esophagus

ABCC2 FKBP1A FAT4 TNXB PLCE1

6.67e-04952155C0279626
DiseaseFEV/FEC ratio

VAPA BOC TET2 KIAA0232 SPEG KIF1B SEC11C ADCY8 DDX5 FCGR2A ANAPC1 CROCC2 SVIL TAL1 ARHGEF28 NEBL RUNX2 SLC1A2 SH3PXD2A TNXB

7.01e-04122821520EFO_0004713
Diseaseforced expiratory volume

VAPA BOC TET2 FILIP1 SETD1A GMPR2 ADCY8 CROCC2 TAL1 PDE11A SLC34A1 SH3PXD2A DROSHA NNT TNXB

7.23e-0478921515EFO_0004314
DiseaseCystic kidney

IFT80 FAT4

7.78e-0462152C0022679
Diseasebilirubin metabolic disorder (is_implicated_in)

ABCC2 UGT1A1

7.78e-0462152DOID:2741 (is_implicated_in)
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A1 SLC1A6

7.78e-0462152DOID:0050994 (implicated_via_orthology)
Diseasecorpus callosum mid-anterior volume measurement

JAG1 SLC1A2 SEPSECS

9.81e-04272153EFO_0010297
DiseaseColorectal Neoplasms

BOC TET2 CPAMD8 LAMA1 ABCB1 ABCC2 APC GUCY2C

1.02e-032772158C0009404
Diseaseresponse to opioid

LRTM2 MVB12B MUC16 NNT

1.03e-03612154EFO_0008541
DiseaseAutism spectrum disorder

SHANK2 SNRPN

1.08e-0372152cv:C1510586
DiseaseCongenital Pain Insensitivity

SCN9A SCN10A

1.08e-0372152C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN9A SCN10A

1.08e-0372152C0020075
Diseaseable to hear with hearing aids

FILIP1 ARHGEF28

1.08e-0372152EFO_0009720
Diseasehyperthyroidism (biomarker_via_orthology)

GSR UGT1A1 SLC34A1

1.09e-03282153DOID:7998 (biomarker_via_orthology)
Diseasechronic kidney disease (biomarker_via_orthology)

CBR1 OPA1 SLC34A1

1.09e-03282153DOID:784 (biomarker_via_orthology)
Diseaseintelligence, response to cranial radiation therapy

ADCY8 TRIM2 RUNX2

1.09e-03282153EFO_0004337, EFO_0010950
Diseasecorpus callosum central volume measurement

JAG1 PIGO MLLT10

1.09e-03282153EFO_0010296
DiseaseEpilepsy

SETD1A ABCB1 SCN9A SLC1A1 SLC1A2

1.24e-031092155C0014544
DiseaseDepressive disorder

ADCY8 ABCB1 NRXN1 NGFR DPYSL2 GRIA3 SLC1A1 SLC1A2

1.33e-032892158C0011581
DiseaseCrohn's disease (is_implicated_in)

ABCB1 FCGR2A UGT1A1

1.34e-03302153DOID:8778 (is_implicated_in)
DiseaseX-linked Adrenal Hypoplasia

MCM4 NNT

1.44e-0382152C0342482
Diseaseblindness (implicated_via_orthology)

ATP6V0E1 PNPLA7

1.44e-0382152DOID:1432 (implicated_via_orthology)
DiseaseAdenocarcinoma

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0001418
DiseaseCarcinoma, Granular Cell

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0205644
DiseaseAdenocarcinoma, Tubular

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0205645
DiseaseAdenocarcinoma, Oxyphilic

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0205642
DiseaseCarcinoma, Cribriform

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0205643
DiseaseAdenocarcinoma, Basal Cell

GMPR2 KRT20 FAT4 APC PLCE1

1.63e-031162155C0205641
Diseasedentures

HAO1 ADCY8 OPA1 CDH9

1.73e-03702154EFO_0010078
Diseasedental caries, dentures

HAO1 ADCY8 OPA1 CDH9

1.73e-03702154EFO_0003819, EFO_0010078
DiseaseRheumatoid Arthritis

ABCB1 FCGR2A ABCC2 RUNX2 CTSD CDK6

1.79e-031742156C0003873
DiseaseRNA-binding protein 24 measurement

C3 PIKFYVE

1.84e-0392152EFO_0802030
Diseasevital capacity

TET2 FILIP1 GMPR2 ADCY8 DDX5 TMEM184A CROCC2 PDE11A RUNX2 MLLT10 OPRL1 SLC34A1 EFR3B NNT TNXB FILIP1L OTOG PLCE1 CDK6

1.85e-03123621519EFO_0004312
Diseaserefractive error, self reported educational attainment

PDE10A RDH5 ARID2

1.93e-03342153EFO_0004784, MONDO_0004892
Diseaseatopic dermatitis (is_marker_for)

FCGR2A NGFR C3

2.10e-03352153DOID:3310 (is_marker_for)
DiseaseDNA-directed RNA polymerases I and III subunit RPAC1 measurement

C3 PIKFYVE

2.29e-03102152EFO_0801535
Diseasenephritis (implicated_via_orthology)

ITGA4 ITGAL

2.29e-03102152DOID:10952 (implicated_via_orthology)
Diseaseabdominal obesity-metabolic syndrome (implicated_via_orthology)

DDX5 GUCY2C

2.29e-03102152DOID:0060611 (implicated_via_orthology)
Diseasepostburn hypertrophic scarring severity measurement

ATF7IP2 DSG1

2.29e-03102152EFO_0007747
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN9A SCN10A

2.29e-03102152DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN9A SCN10A

2.29e-03102152DOID:0080422 (implicated_via_orthology)
DiseaseOCIA domain-containing protein 1 measurement

C3 PIKFYVE

2.29e-03102152EFO_0008252
Diseasepneumonia (implicated_via_orthology)

ITGA4 C3

2.29e-03102152DOID:552 (implicated_via_orthology)
Diseaseasthma (is_marker_for)

ABCB1 FCGR2A C3 CASP1 MUC5B

2.35e-031262155DOID:2841 (is_marker_for)
Diseaseheart failure

FOXN3 ACTN2 KLHL3 BPTF OCRL CDK6

2.43e-031852156EFO_0003144
Diseaseresponse to risperidone

ATF7IP2 MVB12B SLC1A1

2.67e-03382153GO_0097336
Diseaseaspartate aminotransferase measurement

STRA8 ABCB1 FCGR2A IFT80 ABCC2 MOS MUC19 OCRL MLLT10 MADD WBP4 CTSD SNRPN PLCE1 CDK6

2.73e-0390421515EFO_0004736
DiseaseSodium measurement

IFT80 UGT1A1

2.78e-03112152C0337443
DiseaseAdverse Event by CTCAE Category

IFT80 UGT1A1

2.78e-03112152C1879645
DiseaseAlzheimer's disease (is_marker_for)

BPTF NGFR CASP1 APC OPA1 GSR CTSD

2.89e-032572157DOID:10652 (is_marker_for)
Diseasenervous system disease (implicated_via_orthology)

KIF1B ATP12A

3.32e-03122152DOID:863 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN9A SCN10A

3.32e-03122152DOID:0060170 (implicated_via_orthology)
Diseasesialic acid-binding Ig-like lectin 14 measurement

ARHGEF28 SIGLEC6

3.32e-03122152EFO_0008284
DiseaseAdverse reaction to drug

ABCB1 C3 ABCC2 UGT1A1

3.36e-03842154C0041755
DiseaseDrug toxicity

ABCB1 C3 ABCC2 UGT1A1

3.36e-03842154C0013221
DiseaseAutism Spectrum Disorders

DIP2A NRXN1 DIO3 SLC1A1

3.50e-03852154C1510586
DiseaseAlcoholic Intoxication, Chronic

PDE10A ANAPC1 DPYSL2 VWF SLC1A2 OPRL1 CDH9

3.64e-032682157C0001973
DiseaseRespiratory Depression

IFT80 SLC23A1

3.91e-03132152C0235063
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

KIF1B C3

3.91e-03132152DOID:332 (biomarker_via_orthology)
DiseaseRespiratory Failure

IFT80 SLC23A1

3.91e-03132152C1145670
Diseaserhinitis (biomarker_via_orthology)

C3 OPA1

3.91e-03132152DOID:4483 (biomarker_via_orthology)
DiseaseRespiratory Insufficiency

IFT80 SLC23A1

3.91e-03132152C0035229
DiseaseMalignant neoplasm of salivary gland

PDZK1 JAG1 SON

4.32e-03452153C0220636
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

HECW1 ITGA4 NRXN1 ATF7IP2 KRT20 FKBP1A RUNX2 PROS1

4.47e-033522158EFO_0007015
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

HECW1 FAT4

4.54e-03142152EFO_0004670, EFO_0006794
Diseaserhinitis (is_marker_for)

NGFR C3 CASP1

4.60e-03462153DOID:4483 (is_marker_for)
DiseaseThrombus

FCGR2A VWF PROS1

4.60e-03462153C0087086
DiseaseSalivary Gland Neoplasms

PDZK1 JAG1 SON

4.89e-03472153C0036095
Diseaseanemia (implicated_via_orthology)

APC SLC4A2

5.21e-03152152DOID:2355 (implicated_via_orthology)
Diseasecolorectal cancer, colorectal adenoma

BOC TET2 HAO1 APC CDH3

5.22e-031522155EFO_0005406, MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
CVPVSIGRIMVSNVT

UMODL1

701

Q5DID0
GGVRMEVVSVTNGSI

UMODL1

841

Q5DID0
GIIDPGSTVTVSVML

VAPA

66

Q9P0L0
MDSTGVSGRIQVPEE

ADCY8

1121

P40145
IGSMTGAEQALLPRV

SLC4A2

241

P04920
MRNSEEQPSGGTTVL

AMOT

1

Q4VCS5
RIMTLVDPNGQGTVT

ACTN2

796

P35609
IPEGTNGVEERMSVI

DPYSL3

351

Q14195
TLSGLEVSMVTAVPG

GSR

301

P00390
GSSSPMGIIVAVVIA

FCGR2A

211

P12318
LTVQAMDRGVPSLTG

FAT4

321

Q6V0I7
GPVQSMVLNVTVRET

FCRL4

366

Q96PJ5
QVATGQMVTIAGVPS

ARID2

871

Q68CP9
SDMVQAERSGIPIVT

C3

336

P01024
VTVPLGTMRATGDFV

AASDH

416

Q4L235
RTGIIFMPGTIQLTA

ACSM4

136

P0C7M7
RVQTGEEGMPLSTIR

CDK6

46

Q00534
MGVQVETISPGDGRT

FKBP1A

1

P62942
MEVADTTGISPTVVG

DNHD1

2126

Q96M86
MEQLSVPVVGTLRGN

C1orf94

86

Q6P1W5
GMTVIRTPLQQSTLG

BPTF

2186

Q12830
LSPGGTQEMEGIVIV

FAM200A

11

Q8TCP9
SVGRSGGMQVVSLAP

ASTL

156

Q6HA08
LGTTTMRVDIPALGV

MUC5B

5181

Q9HC84
MVREPGEGLAVTVSL

PCOLCE

346

Q15113
TRMAGAIPLVTAGSQ

TP53I3

161

Q53FA7
VGSRGTIEINPRDTM

CRYZ

246

Q08257
PGRLVAEMEVGTEQT

RIMBP3B

1511

A6NNM3
PGRLVAEMEVGTEQT

RIMBP3C

1511

A6NJZ7
IPQGEVGSSNMVSRK

RIC1

1386

Q4ADV7
GRGPQILMIAVFTLT

GUCY2C

426

P25092
SVPIIMGVNVGTSIT

SLC34A3

156

Q8N130
SVPENISSGTRVLMV

PCDHGA11

251

Q9Y5H2
TDITPQGVAMRAGVL

PDZK1

161

Q5T2W1
PTEGMVSVDGQDIRT

ABCB1

446

P08183
NLPTRTMTRQDGETG

ARHGEF28

1681

Q8N1W1
NGSMVRITIPEIATS

ANAPC1

601

Q9H1A4
FDRTGQMSVVITPGV

DEPDC5

326

O75140
VTGELTMTFPAGIVR

FCHO1

651

O14526
AGVRMVVPTQSAQGT

HCFC1

521

P51610
MGGVRLVTPVTVSAV

HCFC1

851

P51610
PRTGIVDISILTTGM

MCM4

776

P33991
NPGLVITTDRMGISR

MUC16

8301

Q8WXI7
VGNVRLVGEVPSSMT

NRXN1

286

P58400
VTSTPVIVMRGAAGL

PASK

871

Q96RG2
TRGTQRLIPQAGTVM

KIAA0100

1356

Q14667
QDSVIGVSPAVMIRS

MADD

1176

Q8WXG6
PTVVNVTILNGMGVT

MBTPS1

511

Q14703
GVSVVMGIPSVRREV

MGAT4B

141

Q9UQ53
IPEGTNGTEERMSVI

DPYSL2

351

Q16555
MPRQATSRLVVGEGE

DIO3

1

P55073
VITEAGDQGMVSVGP

HECW1

421

Q76N89
SVTSIQERIMSTPGG

KIF1B

456

O60333
LMVTGPVATVGIFAT

AQP7P3

146

A6NL99
EGTVTGMVINTGDRT

ATP12A

266

P54707
PVALSGLDMVGVAQT

DDX5

126

P17844
MSEPIRVLVTGAAGQ

MDH1

1

P40925
PNTISIGGLFMRNTV

GRIA3

31

P42263
VVTIAGTDVFMTPGN

KIAA0232

966

Q92628
MVSGTSFQRVIPEDG

OGDHL

861

Q9ULD0
MATGITNIISGRSQP

MUC19

8011

Q7Z5P9
PIVSRGSVIGVVQMV

PDE10A

371

Q9Y233
MPIRSSDGEIIGVAQ

PDE11A

326

Q9HCR9
VIAATGSVGPTVLEM

EFR3B

321

Q9Y2G0
IVMGPNSNIRTVASV

FRYL

1651

O94915
VLGQRVSMPICVGAT

HAO1

66

Q9UJM8
TPIAAMLRGQSDVGV

KLHL9

526

Q9P2J3
TQITAGLDPVGRIQM

GNB2

31

P62879
IMAGQLVAVIGPVGS

ABCC2

661

Q92887
GLPGFSVENIMTLRT

FOXC2

266

Q99958
SGVPIIAANMDTVGT

GMPR2

46

Q9P2T1
SVRNGPESGSKIMVQ

MED17

581

Q9NVC6
TVSRSVAPMRGGEIT

HEG1

441

Q9ULI3
VGNVRLVGEVPSSMT

NRXN1

1291

Q9ULB1
VVIAGGTMQPVSDFR

DDX11

616

Q96FC9
GMGAPLVSVAVVART

OSGEP

81

Q9NPF4
LQAPVVSTVGMQRLG

KRT20

16

P35900
VSTVGMQRLGTTPSV

KRT20

21

P35900
VVTERVIQPTSGMIG

DSG1

921

Q02413
LTRPGEMVGQLAVLT

PNPLA7

521

Q6ZV29
IVMVTQGPSERTLSI

PPFIBP2

316

Q8ND30
ESQVIMSGLIAPETG

MACF1

1581

Q9UPN3
SMDPITGVGVVASRN

MVB12B

46

Q9H7P6
VRMVVGAAGGTQITT

GGTLC3

121

B5MD39
SRVILQPIEGIMGSD

PTPRS

1431

Q13332
SVPVMGVSVALGTIE

THAP12

371

O43422
VSSAIPIIMGSNIGT

SLC34A1

181

Q06495
RSTSMPQLGERSGVI

PCTP

136

Q9UKL6
LVDLPGVINTVTSGM

OPA1

396

O60313
VMPSEVSEVLSVGGR

BTBD18

576

B2RXH4
EVAVVMPTLARGGAA

C6orf132

781

Q5T0Z8
IRLPEMSGGQTNRTT

PIKFYVE

1716

Q9Y2I7
TGMLRSTLAQQGTPV

IFT80

136

Q9P2H3
PMTTARSRVGVAVVN

KLHL18

321

O94889
TIERPVGTGAMVARS

BOC

836

Q9BWV1
IPRRTGAEVDITGMT

CASP1

176

P29466
IAGTINPSVAMAIAG

DOCK6

1206

Q96HP0
PGGRSSELMDVATVQ

CROCC2

1351

H7BZ55
ERTMSPIQVLAVTGS

FILIP1L

996

Q4L180
MTFRPGDQIEVTLSG

FRRS1

56

Q6ZNA5
TRFVLPVGATINMDG

SLC1A2

386

P43004
ITPIGVTAAMRNGIT

FOXN3

296

O00409
EAIVDTGTSLMVGPV

CTSD

291

P07339
TGTSLMVGPVDEVRE

CTSD

296

P07339
ERATASIIGDVMGPT

CPAMD8

1116

Q8IZJ3
SRLPMSIIIVGVGNA

CPNE7

536

Q9UBL6
RAVVIAGGTMQPVSD

DDX11L8

616

A8MPP1
GRVRVIVTGAAPMST

ACSL5

411

Q9ULC5
VVTRTMVRTENGSEP

SLC1A6

206

P48664
PQGRVVNVSSIMSVR

CBR1

131

P16152
GVVQMPESTVTSTVG

ATF7IP2

176

Q5U623
MTEQVIGANSVPGII

MS4A18

1

Q3C1V0
GAPMQSTIREEGRVF

ITGA4

326

P13612
PMNTRRSSVGVGVVE

KLHL3

426

Q9UH77
MPVQLTTALRVVGTS

HAS3

1

O00219
LSVLTVQDVGQVMPG

DIP2A

711

Q14689
AQPSETTVGNMVRRV

EIF2B2

71

P49770
SGIPIIVANMDTVGT

GMPR

46

P36959
SVNEDRPMGSTIVVI

CELSR3

866

Q9NYQ7
IMTGTVQRVALEGRP

GRIP2

896

Q9C0E4
MRLGAQTPVGVSTLE

FARP2

16

O94887
VHLSNVGPEMTGVTV

SDK1

716

Q7Z5N4
RGPLDSTVIDGMSVV

SDK2

406

Q58EX2
FGTNIGSAVVMLIPT

SCAMP5

141

Q8TAC9
GSTMARVGSIVSPLV

SLC22A6

461

Q4U2R8
ASVPEMSGVGTSVIQ

CDH9

166

Q9ULB4
QIMTTAPRQGGLGVV

CCDC184

91

Q52MB2
RGSVLEGVLPGTSVM

CDH3

221

P22223
EGVLPGTSVMQVTAT

CDH3

226

P22223
RFVLPVGATINMDGT

SLC1A1

356

P43005
GATATVTVLVERVMP

CDH16

546

O75309
GRMVIQDIPAVTSRG

DMRT1

181

Q9Y5R6
VGVSGNVVTVMLIGR

MLNR

51

O43193
QEVSGRPCITMGSVI

JAG1

856

P78504
DGTILQQVTVPVSGM

NFYA

176

P23511
VGTVTMGPSARGISV

MED20

126

Q9H944
PEGSVDGDTRMVLVN

SERPINB2

186

P05120
TSGVLPVAEGTASMV

OTOG

1896

Q6ZRI0
RTPAGSNSLGTIIME

MOS

126

P00540
ALASVVGVPVAIMGS

OPRL1

176

P41146
TLTAAIGGADMPVVI

NNT

821

Q13423
IGGADMPVVITVLNS

NNT

826

Q13423
QQLGTVRPGLGMTSV

RETSAT

376

Q6NUM9
GEVPDGTVVTVMAGN

RUNX2

146

Q13950
MLPVIRSTAGGDSVQ

RRN3

536

Q9NYV6
AIGEVRVPMSSVDLG

SYT5

206

O00445
VGTPMSLTGQRFTVQ

TAF9

176

Q16594
TGISPIDVMNSIARG

ATP6V1B1

166

P15313
EGRGGSITQIPILTM

ATP6V1B1

336

P15313
GPNRGVIITMLVTCS

ATP6V0E1

31

O15342
PMDQVGDSTVVGTSR

DROSHA

426

Q9NRR4
VSVGLGDSRTGEMTV

POLR3D

361

P05423
GSESPIVVVLSGSME

SEC11C

56

Q9BY50
SNRGTLMELGISPIV

SEC61A2

71

Q9H9S3
VMTPQGRGTVAAAAV

SNRPN

141

P63162
VSMPQTTAGTILDGV

SVIL

1716

O95425
VGRQTLATTPMGDVE

RIMS4

106

Q9H426
VQPVMGISLTLSRGT

TMEM132A

641

Q24JP5
NGRRMVDVPVTSTGV

FILIP1

791

Q7Z7B0
PASVRRAMGTVIIAG

LRTM2

301

Q8N967
VDGQSVMVEPGTTVL

NDUFS1

36

P28331
MGISPLGNQSVIIET

PLCE1

161

Q9P212
RVAEATGETPIAVMG

RFX2

656

P48378
RVAQATGETPIAVMG

RFX3

641

P48380
PGRLVAEMEVGTEQT

RIMBP3

1511

Q9UFD9
ASVTAELPGDGRMVQ

TAL1

106

P17542
MSNVSGILETAGVPL

TMEM184A

1

Q6ZMB5
ITVDGRESPMVTVVG

LAMA1

2811

P25391
AGVASMNITLGVPRI

POLR3A

1056

O14802
GMRVVVNALIGAIPS

SCN9A

1306

Q15858
QVTFPGAGVTMERTI

SIGLEC6

216

O43699
RGNIPTLGSVAVTMA

ST3GAL3

296

Q11203
VEGSNPTMRGVLQRI

SLC25A41

316

Q8N5S1
GRTVPSQIMGLVVVA

NPAS3

301

Q8IXF0
VGAESQMIVLSSRPV

ITGAL

601

P20701
TLNIRPSTGTGVMLA

PROS1

511

P07225
RVLNVNTMGPIGVTL

RDH5

131

Q92781
PTAGTVGRVLAMLVQ

SETD1A

786

O15047
IRDIATETVGTGIMG

OCRL

336

Q01968
ITMERSFQGPVLIGS

SUCLA2

171

Q9P2R7
MAEVETTTNVGVPGR

SNED1

236

Q8TER0
PGRTIVAVGSMEEAV

SHANK2

1371

Q9UPX8
QTMDLLTGSGIITPQ

STRA8

156

Q7Z7C7
VPGTGSIQMSEISVT

BRS3

371

P32247
IGPVGTGLDSRVMVT

AHNAK2

5751

Q8IVF2
GIVGALNGVMQTPVT

MLLT10

911

P55197
SVPASVVSRIMGRGG

ANKHD1

1701

Q8IWZ3
VGNGSVPMRTVGLEN

APC

2706

P25054
MVLAQSRVSAGVGSP

TGIF1

1

Q15583
IMGGLEVISITDNTP

MRPS11

166

P82912
MAQVRETSLPSGSGV

USP51

1

Q70EK9
STQSGRPGTMEQAIR

TTC8

126

Q8TAM2
RNILVGTTGPIMAQL

UBAP1

181

Q9NZ09
PTACTIQLRGGQIMT

VWF

2646

P04275
DGAPQVVAVTGRMVT

SPEG

1286

Q15772
PRIREVQGAIMVSSV

SLC23A1

151

Q9UHI7
EQSSTVLTGLRPGME

TNN

846

Q9UQP3
SNRGTLMELGISPIV

SEC61A1

71

P61619
NVPIMVTETSGRAGI

GTF2A1L

136

Q9UNN4
VVTTVMGSSQPVVTR

NGFR

231

P08138
GMRVVVDALVGAIPS

SCN10A

1266

Q9Y5Y9
MTGRRPLSQATGAVV

SH2D3A

96

Q9BRG2
QMAGSVVVQLSGLPV

TTYH2

176

Q9BSA4
SGTPAVKMRNGVRQV

SH3PXD2A

961

Q5TCZ1
GRLSQVSEVPLMVVS

WDR97

1391

A6NE52
HDGQRMGPLSVVIVT

TNXB

1546

P22105
GQRMGPVSVVGVTAA

TNXB

2061

P22105
GIVVFSLGSMVSEIP

UGT1A1

301

P22309
TVTSLGVMADGVAPV

WBP4

341

O75554
LQSAMTEGGVVLREP

MRPL18

161

Q9H0U6
ILISMQIVGPSDGSS

TM2D1

166

Q9BX74
ACVIRGQVMTSDGTP

TENM4

921

Q6N022
GPNRGVIITMLVATA

ATP6V0E2

31

Q8NHE4
VPAGRSMLVVARGSQ

SGSM1

451

Q2NKQ1
MGTEPVLQRGETTTS

SYT10

191

Q6XYQ8
VQTGITAAEPGGRTM

TAMM41

361

Q96BW9
ANLPRTGAGMVEVTS

ZNF644

1291

Q9H582
IHGPIRIRSMQTGIT

USP37

6

Q86T82
STQEGARPGMVLSDI

ZGRF1

1396

Q86YA3
VSGASMVLPRAVAGL

PIGO

736

Q8TEQ8
SQDPTMIGVAVDTVG

PSMD5

306

Q16401
MGSVGSQRLEEPSVA

SLC29A4

1

Q7RTT9
SGARVVPLGSMQTVS

SEPSECS

401

Q9HD40
TGEGLRQTIIGQPMS

TRIM2

331

Q9C040
RQTIIGQPMSVTITT

TRIM2

336

Q9C040
GPFVEGSIVRISMEN

SMC5

46

Q8IY18
VEMSGPVTVLTRQTT

TET2

1056

Q6N021
VVMVTVTAGGREANP

VWA7

801

Q9Y334
NLMTPEGVGLTTALR

VIRMA

921

Q69YN4
TGTGLTPVMTQALRR

PRR11

321

Q96HE9
TTATGLLGQPEATMV

SON

531

P18583
VGETSVTVGVDPLMA

SON

696

P18583
PGTTMLRVAGGVITT

YEATS2

941

Q9ULM3
ITGSMVPLLQVISRG

UBE3C

471

Q15386
AEMAATIERTTGPVG

TRERF1

1126

Q96PN7
APMNTRRSSVGVGVV

KLHL2

431

O95198
SGVMGISSDQVRLLP

LEG1

146

Q6P5S2
GQLGRATTLSVTPEM

NEBL

721

O76041