Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalmodulin binding

PHKB MYO15A AEBP1 MYO7A MAPKAPK3

4.75e-05230355GO:0005516
DomainMYTH4

ARHGAP39 MYO15A MYO7A

4.19e-079333PS51016
DomainMyTH4_dom

ARHGAP39 MYO15A MYO7A

4.19e-079333IPR000857
DomainMyTH4

ARHGAP39 MYO15A MYO7A

4.19e-079333SM00139
DomainMyTH4

ARHGAP39 MYO15A MYO7A

4.19e-079333PF00784
DomainVWFC_1

DGCR2 VWC2

1.84e-0336332PS01208
DomainMYOSIN_MOTOR

MYO15A MYO7A

2.05e-0338332PS51456
DomainVWC

DGCR2 VWC2

2.05e-0338332SM00214
DomainMyosin_head

MYO15A MYO7A

2.05e-0338332PF00063
DomainMyosin_head_motor_dom

MYO15A MYO7A

2.05e-0338332IPR001609
DomainMYSc

MYO15A MYO7A

2.05e-0338332SM00242
DomainVWFC_2

DGCR2 VWC2

2.05e-0338332PS50184
DomainVWF_dom

DGCR2 VWC2

2.49e-0342332IPR001007
DomainFERM_M

MYO15A MYO7A

2.98e-0346332PF00373
DomainFERM_central

MYO15A MYO7A

3.38e-0349332IPR019748
DomainFERM_domain

MYO15A MYO7A

3.38e-0349332IPR000299
DomainFERM_1

MYO15A MYO7A

3.52e-0350332PS00660
DomainFERM_2

MYO15A MYO7A

3.52e-0350332PS00661
DomainBand_41_domain

MYO15A MYO7A

3.52e-0350332IPR019749
DomainB41

MYO15A MYO7A

3.52e-0350332SM00295
DomainFERM_3

MYO15A MYO7A

3.52e-0350332PS50057
DomainSH3

MYO15A MYO7A TP53BP2

6.45e-03216333PS50002
DomainSH3

MYO15A MYO7A TP53BP2

6.45e-03216333SM00326
DomainSH3_domain

MYO15A MYO7A TP53BP2

6.78e-03220333IPR001452
DomainIQ

MYO15A MYO7A

6.97e-0371332PF00612
DomainIQ

MYO15A MYO7A

8.99e-0381332SM00015
DomainIQ_motif_EF-hand-BS

MYO15A MYO7A

1.10e-0290332IPR000048
DomainIQ

MYO15A MYO7A

1.17e-0293332PS50096
Pubmed

Investigation of MYO15A and MYO7A Mutations in Iranian Patients with Nonsyndromic Hearing Loss.

MYO15A MYO7A

9.84e-07235231997689
Pubmed

Cy3-ATP labeling of unfixed, permeabilized mouse hair cells.

MYO15A MYO7A

9.84e-07235234903829
Pubmed

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.

PHKB LSR PDZD11 TP53BP2

1.80e-068735417979178
Pubmed

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.

MYO15A MYO7A

2.95e-06335215654330
Pubmed

ASPP2 suppression promotes malignancy via LSR and YAP in human endometrial cancer.

LSR TP53BP2

2.95e-06335232266459
Pubmed

Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.

MYO15A MYO7A

5.90e-06435230275467
Pubmed

Heterogeneity of Hereditary Hearing Loss in Iran: a Comprehensive Review.

MYO15A MYO7A

5.90e-06435227743438
Pubmed

Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia.

MYO15A MYO7A

5.90e-06435212966030
Pubmed

The role of mouse mutants in the identification of human hereditary hearing loss genes.

MYO15A MYO7A

5.90e-06435210320095
Pubmed

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

MYO15A MYO7A

5.90e-06435215590698
Pubmed

Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia.

MYO15A MYO7A

9.82e-06535218160714
Pubmed

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.

MYO15A MYO7A

9.82e-06535220332152
Pubmed

Genomics and hearing impairment.

MYO15A MYO7A

1.47e-0563529927480
Pubmed

Myosins: a diverse superfamily.

MYO15A MYO7A

2.06e-05735210722873
Pubmed

Tails of unconventional myosins.

MYO15A MYO7A

2.06e-05735211212352
Pubmed

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.

MYO15A MYO7A

2.06e-05735221436032
Pubmed

[Studies on the genetics and pathology of the development of 8 labyrinth mutants (deaf-waltzer-shaker mutants) in the mouse (Mus musculus)].

MYO15A MYO7A

2.06e-05735213853422
Pubmed

Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV.

MYO15A MYO7A

2.74e-05835215702992
Pubmed

Molecular characterization of seizure-related genes isolated by differential screening.

DGCR2 SEZ6

3.53e-0593528645260
Pubmed

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.

MYO15A MYO7A

3.53e-05935219339464
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PHKB LSR ACOT2 KANK2 PI4KA TP53BP2

4.08e-0564535625281560
Pubmed

Gene mapping of SEZ group genes and determination of pentylenetetrazol susceptible quantitative trait loci in the mouse chromosome.

DGCR2 SEZ6

4.40e-051035210700579
Pubmed

Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation.

MYO15A MYO7A

6.45e-051235229769265
Pubmed

CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.

MYO15A MYO7A

6.45e-051235228663585
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PHKB ARHGAP39 MYO7A KANK2 AJM1 PI4KA TP53BP2 STAU1

7.02e-05143135837142655
Pubmed

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.

MYO15A MYO7A

8.89e-051435226754646
Pubmed

Identification of genes concordantly expressed with Atoh1 during inner ear development.

MYO15A MYO7A

1.66e-041935221519551
Pubmed

An Ideal PPAR Response Element Bound to and Activated by PPARĪ±.

ACOT2 CDH15

1.85e-042035226241474
Pubmed

The small GTPase Rac1 regulates auditory hair cell morphogenesis.

MYO15A MYO7A

2.46e-042335220016102
Pubmed

The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

ACOT2 CDH15

3.93e-042935228364022
Pubmed

Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system.

SELPLG ACOT2

6.76e-043835218407958
Pubmed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

LSR AEBP1 ERAP1 STAU1

7.95e-0441735419199708
Pubmed

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

MYO15A MYO7A

9.06e-044435227534441
Cytoband22q11.21

DGCR2 PI4KA

3.27e-0311135222q11.21
CytobandEnsembl 112 genes in cytogenetic band chr9q33

RC3H2 B3GALT9

5.00e-03138352chr9q33
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO15A MYO7A

1.99e-03502421293
GeneFamilyActins|Deafness associated genes

MYO15A MYO7A

9.77e-031132421152
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TP53BP2 STAU1

2.38e-02181242694
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FMOD TM6SF2 PDZD11 SEZ6

6.36e-06154354cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWC2 FMOD AEBP1 KHDRBS2

8.76e-06167354351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWC2 FMOD AEBP1 KHDRBS2

8.76e-06167354c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LSR FMOD MYO7A RADX

9.62e-06171354b113fbebb89056af0b9c775d2fb6552206a80467
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LSR FMOD AEBP1 KHDRBS2

9.84e-061723549a256db817c1af1802203cc88a55d608fb328c63
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

AADAC LSR KANK2 ASCL5

9.84e-061723540be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 AEBP1 RGS7 CDH15

1.43e-051893546b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 AEBP1 RGS7 CDH15

1.43e-05189354344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AADAC FMOD AEBP1 KANK2

1.61e-051953540866aaf053762d1a021fcbccff058526078a99da
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

AADAC FMOD AEBP1 KANK2

1.78e-05200354c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell18-Airway-Mesenchymal|Airway / Age, Tissue, Lineage and Cell class

LAPTM4A FMOD AEBP1 KANK2

1.78e-05200354aca1e8def8ed6ae5749402d0288ad90656213de1
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

ARHGAP39 CFAP44 ASCL5

1.72e-0413835393497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG VWC2 KHDRBS2

2.42e-04155353f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG VWC2 KHDRBS2

2.42e-041553530e24e767a3895d31d34cabeaca0354aadae34e44
ToppCell356C-Lymphocytic-ILC-ILC-2|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO7A RADX SEZ6

2.42e-041553530fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG RADX MAPKAPK3

2.61e-041593535c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELPLG RGS7 CDH15

2.66e-04160353dee756a2dc9725520d439e7273c489c2284015d8
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG MYO7A MAPKAPK3

2.76e-0416235358fe827198c172eeaa26273b0fad7991a718b0bf
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG RADX MAPKAPK3

2.81e-04163353476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM6SF2 RADX PI4KA

2.96e-041663530a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LSR FMOD AEBP1

2.96e-04166353545f6c91102568791443717e522f89cb3bd1a070
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

FMOD AEBP1 KANK2

3.07e-04168353838ce47d4958ba12047882f97925eddd02f081c7
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMOD AEBP1 KANK2

3.07e-04168353b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELPLG LSR MYO15A

3.07e-04168353ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AADAC LSR RGS7

3.17e-04170353fcaa32607bcbd8be6f040f9487c3d71e976e1077
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NDFIP2 LSR MAPKAPK3

3.17e-04170353aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VWC2 AEBP1 SEZ6

3.17e-0417035314aa86a4f526ed6986afcb28c49225522055550c
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAPTM4A FMOD AEBP1

3.23e-041713532e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AADAC LSR FMOD

3.23e-04171353a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SELPLG AEBP1 RGS7

3.23e-041713531f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAPTM4A FMOD AEBP1

3.23e-04171353e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell3'_v3-GI_small-bowel-Mast-Mast_cell_granulo-myelo|GI_small-bowel / Manually curated celltypes from each tissue

VWC2 LAPTM4A AADAC

3.28e-041723533df11aefc09762fd1f94441324551178e030b249
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDFIP2 LSR MAPKAPK3

3.34e-041733530f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWC2 NDFIP2 LAPTM4A

3.34e-041733533a39c7f290a9914fcf747e6bc6f13a509413b33c
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

VWC2 NDFIP2 AEBP1

3.45e-04175353eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

VWC2 NDFIP2 AEBP1

3.45e-04175353ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

FMOD MYO7A RADX

3.45e-041753537de1023161233b64f11e130881c742f4cf2bff65
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VWC2 AEBP1 SEZ6

3.51e-0417635305ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC MYO15A CFAP44

3.63e-041783538b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC MYO15A CFAP44

3.63e-0417835358857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC MYO15A CFAP44

3.63e-04178353b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AADAC FMOD AEBP1

3.75e-04180353c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AADAC FMOD AEBP1

3.75e-0418035332c6a3886428d82fb4355d987c6d2645f333447b
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWC2 NDFIP2 AEBP1

3.81e-04181353f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR MYO7A RADX

3.87e-041823533dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

AEBP1 RGS7 KHDRBS2

3.87e-04182353310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDFIP2 LSR MAPKAPK3

3.94e-0418335326b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR MYO7A RADX

3.94e-0418335342dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 MYO15A KANK2

3.94e-04183353262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 MYO15A KANK2

3.94e-04183353c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AADAC LSR FMOD

4.00e-04184353e93633d89a9c54c8d2819f56372815b4ca149f06
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LSR ARHGAP39 MYO7A

4.00e-0418435315ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LSR ARHGAP39 MYO7A

4.00e-04184353bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.06e-041853537b1c5d99bd7a6e148524029758cee244a17f5d09
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LSR MYO7A RADX

4.06e-0418535357c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.06e-04185353e9033a03d574956cf3ae228740b3166e40a6397f
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR MYO7A RADX

4.06e-04185353afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR MYO7A RADX

4.06e-04185353775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellILEUM-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SELPLG AEBP1 RGS7

4.06e-04185353308a98f111895071d8772bc010554471cc12fab2
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.06e-04185353578f12c6b2e33d09598dc8e022a20c8555d1325c
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR ARHGAP39 MYO7A

4.13e-041863538f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VWC2 LSR FMOD

4.13e-041863531587667e5084ac43505d027af925ba711e228150
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR ARHGAP39 MYO7A

4.13e-04186353f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell367C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VWC2 NDFIP2 LAPTM4A

4.19e-041873537d416693cb719df4197a11acc6b4e19171352515
ToppCellControl-Fibroblasts-Pathological_FB|Control / group, cell type (main and fine annotations)

LAPTM4A FMOD AEBP1

4.19e-04187353b7280b8baa0fba9c2b4bff660c240ed96f6ff9b7
ToppCell367C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VWC2 NDFIP2 LAPTM4A

4.19e-04187353b1341d272d9fc07c6f7590d6d398d7a5cf42240b
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AADAC LSR FMOD

4.39e-04190353422f58447e2b308f6f9dad822c4600c78e571c5d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 SEZ6 KHDRBS2

4.39e-041903539b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC LSR MAPKAPK3

4.39e-04190353a124e1c12af70161b9ead5d677afa660610444ee
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 SEZ6 KHDRBS2

4.39e-04190353d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

VWC2 NDFIP2 LAPTM4A

4.46e-04191353781f6005673fc3504a85801a68af3e16ca84952f
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWC2 AEBP1 RGS7

4.46e-0419135324dc77ee8de01b42559f92721655f4281b114e17
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDFIP2 CFAP44 B3GALT9

4.53e-04192353dcf2d0c2e8868104c4dba410456207f0d947029a
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FMOD AEBP1 KANK2

4.53e-04192353c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD TM6SF2 AEBP1

4.53e-04192353b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NDFIP2 LAPTM4A AADAC

4.53e-041923539ad9dce4fcbb133b135079eb4cc32c7ead7f0243
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDFIP2 CFAP44 B3GALT9

4.53e-04192353a22952b885c8a7704a4a9602fa03e4f2c786bf75
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 MYO15A KANK2

4.60e-04193353f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 MYO15A KANK2

4.60e-041933534ccf984baebbb13ae916727137ce593fda7514a2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.60e-041933535bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AADAC FMOD AEBP1

4.67e-0419435302b8102be9414d6964cd71019613edff6d88b893
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AADAC FMOD AEBP1

4.67e-0419435329f83cdd63314fff41258937d70b881a5503bfcc
ToppCell3'_v3-Lung-Mast|Lung / Manually curated celltypes from each tissue

VWC2 NDFIP2 LAPTM4A

4.67e-041943535e6eb81ddc9d5e22c1297734689f476d5a05bff6
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FMOD AEBP1 KANK2

4.67e-0419435329a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AADAC FMOD AEBP1

4.67e-04194353d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell3'_v3-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

VWC2 NDFIP2 LAPTM4A

4.67e-041943537b7f1714c4a9d9519c4d0e460cb87f2eb82392dd
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.81e-04196353b55aa507429ddce89ad4f42ab6daeca2f34fd676
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.81e-04196353cda3681f032f740cb09c64c62b9153cb62dbb5d2
ToppCellCOPD-Stromal-Myofibroblast|COPD / Disease state, Lineage and Cell class

FMOD AEBP1 KANK2

4.81e-04196353af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

FMOD AEBP1 KANK2

4.81e-041963532d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDFIP2 LSR MAPKAPK3

4.81e-0419635322fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.81e-0419635369ad90a429af4dad5a45556544224001ebcb1607
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAPTM4A FMOD AEBP1

4.81e-0419635361bee32ca299219f31a30b57124e44e85b798e9f
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

NDFIP2 MYO7A MAPKAPK3

4.81e-041963535a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.81e-041963534da96672a9c72268cfcc82d61eb3caae6e02d4c4
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMOD AEBP1 KANK2

4.81e-04196353f78951b460913866d092ba92af70ea76a2afa73e
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

SELPLG PHKB TP53BP2

4.88e-04197353c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMOD AEBP1 KANK2

4.88e-04197353da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

FMOD AEBP1 KANK2

4.88e-04197353d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VWC2 FMOD AEBP1

4.88e-04197353a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
Diseasesensorineural hearing loss (is_implicated_in)

MYO15A MYO7A

5.53e-0433312DOID:10003 (is_implicated_in)
Diseasemouth morphology measurement

FMOD RGS7

1.27e-0350312EFO_0007955
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

MYO15A MYO7A

1.32e-0351312cv:CN043650
Diseaseaspartate aminotransferase measurement

MYO15A TM6SF2 MYO7A STAU1 KHDRBS2

2.34e-03904315EFO_0004736
DiseaseNonsyndromic genetic hearing loss

MYO15A MYO7A

2.90e-0376312cv:C5680182
DiseaseNonsyndromic Deafness

MYO15A MYO7A

3.29e-0381312C3711374
Diseasecarpal tunnel syndrome

AEBP1 KANK2

3.95e-0389312EFO_0004143
Diseasecholesteryl ester measurement, intermediate density lipoprotein measurement

TM6SF2 KANK2

4.40e-0394312EFO_0008595, EFO_0010351
Diseasehearing impairment

MYO15A MYO7A

4.77e-0398312C1384666
DiseaseHbA1c measurement

MYO15A AEBP1 CDH15 SEZ6

5.23e-03675314EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
PPYYDAYAGVFPYVP

ASCL5

126

Q7RTU5
AYYIYTPLPDNVEEP

AADAC

16

P22760
YDDMDYYFGPPPPQK

AEBP1

311

Q8IUX7
TFDAYYPRPYPSEEL

AJM1

301

C9J069
CYPETGHYIEPPYFP

ACOT2

416

P49753
FPDIIIYEYPSLRPY

CFAP44

206

Q96MT7
PHVLDVYLEEYPPYP

TP53BP2

856

Q13625
IPFEVPQYPQTGYYP

RC3H2

606

Q9HBD1
PSSPRYGYEPPLYEE

ARHGAP39

301

Q9C0H5
YGYEPPLYEEPPVEY

ARHGAP39

306

Q9C0H5
PLYEEPPVEYQAPIY

ARHGAP39

311

Q9C0H5
YYPYPPVPETFSKYS

RADX

506

Q6NSI4
PYETYEPYPYGVDEG

FMOD

46

Q06828
PYYVAPEVLGPEKYD

MAPKAPK3

206

Q16644
APYPPYDLPYHTPYD

MYO15A

351

Q9UKN7
AIYPPEVPYFYPEES

MYO15A

391

Q9UKN7
YPAFEAPPQYVLPTY

LAPTM4A

201

Q15012
EFYEDYFSIPYPLPK

ERAP1

291

Q9NZ08
PYDDYPVVFLPAYEN

PDZD11

6

Q5EBL8
YYDIPDAPYRITVPD

PI4KA

1031

P42356
VYGEFYPVPPPYSVA

NDFIP2

166

Q9NV92
PHYYTPPYLTAEPEV

PDP2

381

Q9P2J9
FHDPPPPYTAYKYPD

DGCR2

426

P98153
KDPDPPYSVETPYGY

KANK2

26

Q63ZY3
YRAPPPPAHEAYEEY

KHDRBS2

256

Q5VWX1
YGCPPPYHTFEEPVY

MT-CO1

496

P00395
PSVPPYDTALIYDYE

CDH15

726

P55291
EGYPVVPKYYYVPAD

PHKB

401

Q93100
EEEAYYPPAPPPYSE

LSR

611

Q86X29
AEPDLLYYPPGVVVY

RXFP3

441

Q9NSD7
YEYLDYDFLPETEPP

SELPLG

46

Q14242
YTEQYLEYDPFLLPP

RGS7

286

P49802
PAPYFAAEARYPIYV

TENT5D

351

Q8NEK8
DFVPLSEYPEKYYPD

B3GALT9

226

A8MXE2
LEPYFPQEPYGDYRP

C11orf53

56

Q8IXP5
EYYYPDGKDFPIPSP

UHRF1BP1L

506

A0JNW5
APTPEPPEEYVYPDY

VWC2

136

Q2TAL6
YFYPFPVPPLLYQVE

STAU1

116

O95793
APPVYDSYEVEYLPI

SEZ6

481

Q53EL9
IYQYEPYLRDPVAYP

TM6SF2

251

Q9BZW4
PYTLEEFSYDYFRPP

MYO7A

1711

Q13402