Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin binding

MYH7 SPATA31A1 SPATA31A3 MYO1A IQGAP2 MYO6 MYH7B SIPA1L1 SPATA31A7 PPP1R9A DIAPH2 MYO15A SPATA31A5 PDLIM5

1.89e-084798714GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH7 SPATA31A1 SPATA31A3 MYO1A IQGAP2 MYO6 MYH7B MYOC SIPA1L1 SPATA31A7 PPP1R9A KIF19 DIAPH2 NAV3 IQCJ-SCHIP1 MYO15A NEDD1 SPATA31A5 PDLIM5 KIF7

3.83e-0810998720GO:0008092
GeneOntologyMolecularFunctionATP-dependent activity

MYH7 MYO1A CCT3 MYO6 MYH7B DDX60 DHX38 KIF19 ERCC6L2 NAV3 NAV2 ABCC2 MYO15A HSPA9 KIF7

5.96e-086148715GO:0140657
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH7 MYO1A MYO6 MYH7B MYO15A

6.26e-0738875GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH7 MYO1A MYO6 MYH7B KIF19 MYO15A KIF7

8.32e-07118877GO:0003774
GeneOntologyMolecularFunctionactin filament binding

MYH7 MYO1A IQGAP2 MYO6 MYH7B SIPA1L1 PPP1R9A MYO15A

6.66e-06227878GO:0051015
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH7 CCT3 DDX60 DHX38 KIF19 NAV3 NAV2 ABCC2 HSPA9 KIF7

2.19e-054418710GO:0016887
GeneOntologyMolecularFunctioncalmodulin binding

MYH7 MYO1A IQGAP2 MYO6 ASPM IQCJ-SCHIP1 MYO15A

6.56e-05230877GO:0005516
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

CNTN5 PKP2 PDLIM5 CNTN1

1.45e-0461874GO:0098632
GeneOntologyMolecularFunctioncell adhesion mediator activity

CNTN5 PKP2 PDLIM5 CNTN1

3.40e-0476874GO:0098631
GeneOntologyMolecularFunctionpyrophosphatase activity

MYH7 CCT3 DCP1B DDX60 DHX38 KIF19 NAV3 NAV2 ABCC2 HSPA9 KIF7

1.03e-038398711GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MYH7 CCT3 DCP1B DDX60 DHX38 KIF19 NAV3 NAV2 ABCC2 HSPA9 KIF7

1.04e-038408711GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MYH7 CCT3 DCP1B DDX60 DHX38 KIF19 NAV3 NAV2 ABCC2 HSPA9 KIF7

1.04e-038408711GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYH7 CCT3 DDX60 DHX38 KIF19 NAV3 NAV2 ABCC2 HSPA9 KIF7

1.97e-037758710GO:0017111
GeneOntologyMolecularFunctionprotein phosphatase activator activity

PPP2R5A PPP2R5E

2.45e-0317872GO:0072542
GeneOntologyBiologicalProcesssupramolecular fiber organization

SLAIN2 FAM171A1 MYH7 MYO1A IQGAP2 ADAMTS3 MYO6 MYOC PPP1R9A KIF19 DIAPH2 MKX NAV3 PKP2 CGNL1 MYO15A NEDD1 PCM1

7.88e-089578718GO:0097435
GeneOntologyBiologicalProcessactin filament-based process

FAM171A1 MYH7 MYO1A IQGAP2 MYO6 MYH7B MYOC SIPA1L1 PPP1R9A DIAPH2 PKP2 CGNL1 MYO15A PDLIM5

2.64e-059128714GO:0030029
GeneOntologyCellularComponentmyosin complex

MYH7 MYO1A MYO6 MYH7B CGNL1 MYO15A

1.76e-0759886GO:0016459
GeneOntologyCellularComponentactin cytoskeleton

MYH7 MYO1A IQGAP2 MYO6 MYH7B SIPA1L1 PPP1R9A DIAPH2 CGNL1 MYO15A PDLIM5

2.97e-055768811GO:0015629
GeneOntologyCellularComponentsupramolecular fiber

SLAIN2 MYH7 PPP2R5A MYO1A CCT3 IQGAP2 MYO6 MYH7B KIF19 ASPM DIAPH2 NAV3 PKP2 PDLIM5 KIF7

1.11e-0411798815GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

SLAIN2 MYH7 PPP2R5A MYO1A CCT3 IQGAP2 MYO6 MYH7B KIF19 ASPM DIAPH2 NAV3 PKP2 PDLIM5 KIF7

1.20e-0411878815GO:0099081
GeneOntologyCellularComponentpericentriolar material

DYNC2I1 NEDD1 PCM1

2.19e-0428883GO:0000242
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

SLAIN2 MYO1A CCT3 IQGAP2 MYO6 KIF19 ASPM DIAPH2 NAV3 PKP2 PDLIM5 KIF7

3.77e-048998812GO:0099513
GeneOntologyCellularComponentfilamentous actin

MYO1A MYO6 PDLIM5

5.47e-0438883GO:0031941
GeneOntologyCellularComponentmicrotubule end

SLAIN2 ASPM NAV3

5.47e-0438883GO:1990752
GeneOntologyCellularComponentactin-based cell projection

MYO1A PTPRH IQGAP2 MYO6 PPP1R9A MYO15A

1.14e-03278886GO:0098858
DomainIQ

MYH7 MYO1A IQGAP2 MYO6 MYH7B ASPM MYO15A

7.67e-0881847SM00015
DomainIQ_motif_EF-hand-BS

MYH7 MYO1A IQGAP2 MYO6 MYH7B ASPM MYO15A

1.60e-0790847IPR000048
DomainIQ

MYH7 MYO1A IQGAP2 MYO6 MYH7B ASPM MYO15A

2.00e-0793847PS50096
DomainMyosin_head_motor_dom

MYH7 MYO1A MYO6 MYH7B MYO15A

7.29e-0738845IPR001609
DomainMYOSIN_MOTOR

MYH7 MYO1A MYO6 MYH7B MYO15A

7.29e-0738845PS51456
DomainMyosin_head

MYH7 MYO1A MYO6 MYH7B MYO15A

7.29e-0738845PF00063
DomainMYSc

MYH7 MYO1A MYO6 MYH7B MYO15A

7.29e-0738845SM00242
DomainP-loop_NTPase

CACNB1 MYH7 MYO1A MYO6 MYH7B DDX60 DHX38 KIF19 ASPM ERCC6L2 NAV3 NAV2 NLRC5 ABCC2 MYO15A KIF7

9.97e-078488416IPR027417
DomainIQ

MYO1A IQGAP2 MYO6 ASPM MYO15A

1.68e-0571845PF00612
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.88e-0512843PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.88e-0512843IPR027970
DomainMyosin_tail_1

MYH7 MYH7B CGNL1

6.82e-0518843PF01576
DomainMyosin_tail

MYH7 MYH7B CGNL1

6.82e-0518843IPR002928
DomainMyosin-like_IQ_dom

MYH7 MYH7B ASPM

8.07e-0519843IPR027401
Domain-

MYH7 MYH7B ASPM

8.07e-05198434.10.270.10
DomainPP2A_B56

PPP2R5A PPP2R5E

1.98e-045842IPR002554
DomainB56

PPP2R5A PPP2R5E

1.98e-045842PF01603
DomainCH

IQGAP2 ASPM NAV3 NAV2

2.09e-0465844SM00033
DomainCH

IQGAP2 ASPM NAV3 NAV2

2.78e-0470844PF00307
Domain-

IQGAP2 ASPM NAV3 NAV2

2.94e-04718441.10.418.10
DomainCH

IQGAP2 ASPM NAV3 NAV2

3.27e-0473844PS50021
DomainCH-domain

IQGAP2 ASPM NAV3 NAV2

3.63e-0475844IPR001715
DomainMyosin_N

MYH7 MYH7B

2.02e-0315842PF02736
DomainMyosin_N

MYH7 MYH7B

2.02e-0315842IPR004009
DomainTSP_1

ADAMTS3 ADGRB2 RSPO1

2.87e-0363843PF00090
DomainFurin_repeat

IGF1R RSPO1

2.92e-0318842IPR006212
DomainFU

IGF1R RSPO1

2.92e-0318842SM00261
DomainTSP1

ADAMTS3 ADGRB2 RSPO1

3.14e-0365843SM00209
DomainTSP1_rpt

ADAMTS3 ADGRB2 RSPO1

3.14e-0365843IPR000884
DomainTSP1

ADAMTS3 ADGRB2 RSPO1

3.14e-0365843PS50092
DomainARM-type_fold

PPP2R5A PPP2R5E ASPM DIAPH2 PKP2 LRBA

4.24e-03339846IPR016024
DomainKazal_1

SPARCL1 SPINK5

4.36e-0322842PF00050
Domainfn3

IGF1R PTPRH CNTN5 CNTN1

6.15e-03162844PF00041
DomainWD40

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

6.26e-03259845PF00400
Domain-

CACNB1 DDX60 DHX38 ERCC6L2 NAV3 NAV2 NLRC5 ABCC2 MYO15A

6.27e-037468493.40.50.300
DomainS100_CABP

RPTN FLG2

6.52e-0327842PS00303
DomainS_100

RPTN FLG2

6.52e-0327842PF01023
DomainS100_Ca-bd_sub

RPTN FLG2

7.00e-0328842IPR013787
DomainS100/CaBP-9k_CS

RPTN FLG2

7.00e-0328842IPR001751
DomainS_100

RPTN FLG2

7.00e-0328842SM01394
DomainWD40

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

7.20e-03268845SM00320
DomainARM-like

PPP2R5A PPP2R5E ASPM PKP2 LRBA

7.43e-03270845IPR011989
DomainWD40_repeat

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

7.66e-03272845IPR001680
DomainWD_REPEATS_1

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

8.37e-03278845PS00678
DomainWD_REPEATS_2

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

8.49e-03279845PS50082
DomainWD_REPEATS_REGION

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

8.49e-03279845PS50294
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SFXN1 SLAIN2 CCT3 IQGAP2 UBR5 MYO6 LEMD3 SURF6 KDM3B PKP2 CGNL1 LRBA FLG2 MGA TASOR HSPA9 PCM1

1.22e-11777891735844135
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5

5.99e-10689420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5

5.99e-10689425930072
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FAM171A1 CACNB1 RANBP2 CCT3 IQGAP2 UBR5 FAM120C SIPA1L1 PPP1R9A ADGRB2 DIAPH2 MGA HSPA9 PCM1 CNTN1 KIF7

2.81e-09963891628671696
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 ADAMTS3 SPATA31A7 SPATA31A5

4.01e-092489532212159
Pubmed

Novel myosin mutations for hereditary hearing loss revealed by targeted genomic capture and massively parallel sequencing.

MYH7 MYO6 MYO15A

1.62e-08389324105371
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SLAIN2 ZNF609 PPP2R5A TUT4 PPP2R5E UBR5 FAM120C TNFSF13B SIPA1L1 SURF6 ASPM PKP2 MGA PSMG3-AS1 PCM1 KIF7

2.23e-081116891631753913
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

FAM171A1 MYO6 FAM120C SIPA1L1 SURF6 PKP2 PCM1

3.53e-0812589729467281
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

IRF2BP2 RANBP2 CCT3 MYO6 SURF6 DHX38 KDM3B CGNL1 LRBA NEDD1 TASOR HSPA9 PDLIM5 PCM1

1.09e-07934891433916271
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SLAIN2 IRF2BP2 RANBP2 ZNF609 MYO6 DHX38 KDM3B ZMYM1 NEDD1 MGA

2.15e-07444891034795231
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZNF609 TUT4 DCP1B LEMD3 KDM3B DYNC2I1 ZMYM1 NEDD1 MGA TASOR PDLIM5 PCM1

3.79e-07733891234672954
Pubmed

Myosins: a diverse superfamily.

MYO1A MYO6 MYO15A

5.63e-07789310722873
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

SFXN1 A2M RANBP2 MYH7 MYO1A UBR5 MYO6 MYH7B LRBA FLG2 HSPA9

8.34e-07647891126618866
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

SLAIN2 RANBP2 ZNF609 PPP2R5A PPP2R5E CCT3 UBR5 LEMD3 DHX38 ASPM DYNC2I1 ZMYM1 NEDD1 PCM1

1.38e-061155891420360068
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SLAIN2 RANBP2 UBR5 SIPA1L1 DYNC2I1 CGNL1 NEDD1 MGA HSPA9 PDLIM5 PCM1 KIF7

1.85e-06853891228718761
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FAM120C DDX60 ASPM CGNL1 LRBA FLG2 HSPA9

2.46e-0623489736243803
Pubmed

Functional proteomics mapping of a human signaling pathway.

A2M PPP2R5E DCP1B UBR5 MYO6 LEMD3 KDM3B PKP2 SPARCL1 MGA

2.84e-06591891015231748
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

A2M IRF2BP2 RANBP2 CCT3 MYO6 PKP2 FLG2 HSPA9 PCM1

3.84e-0647789931300519
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

RANBP2 ERCC4 CCT3 UBR5 DHX38 KDM3B MGA HSPA9

3.91e-0635789837059091
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RANBP2 MYH7 CCT3 IQGAP2 MYO6 SIPA1L1 PKP2 FLG2 HSPA9 PCM1

4.72e-06626891033644029
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

IRF2BP2 IGF1R MYO6 SURF6 KIF19 ERCC6L2 DIAPH2 NAV2 LRBA

5.34e-0649789936774506
Pubmed

Interaction of myocilin with the C-terminal region of hevin.

MYOC SPARCL1

6.48e-06289216316624
Pubmed

Inhibition of IGF-IR increases chemosensitivity in human colorectal cancer cells through MRP-2 promoter suppression.

IGF1R ABCC2

6.48e-06289222275271
Pubmed

The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss.

MYO1A MYO6

6.48e-06289225080041
Pubmed

Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI.

MYO1A MYO6

6.48e-06289226286357
Pubmed

Multiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing loss.

MYO1A MYO6

6.48e-06289212736868
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

SLAIN2 IRF2BP2 UBR5 SIPA1L1 MGA PCM1

8.16e-0618489632908313
Pubmed

JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase.

RANBP2 NEDD1 HSPA9

8.86e-061689326291670
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

SFXN1 IRF2BP2 PPP2R5A PPP2R5E IQGAP2 MYO6 GOLIM4 PKP2 HSPA9

1.38e-0556089935241646
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

FAM171A1 RANBP2 ZNF609 PPP2R5A PPP2R5E PTPRH CCT3 LEMD3 PPP1R9A DHX38 GOLIM4 KIF7

1.49e-051049891227880917
Pubmed

Human transcription factor protein interaction networks.

SFXN1 IRF2BP2 ZNF609 ERCC4 CCT3 DCP1B MYO6 SURF6 RLIM ZMYM1 FLG2 MGA PCM1 KIF7

1.57e-051429891435140242
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CCT3 MYH7B DDX60 SIPA1L1 HSPA9 PHTF1

1.64e-0520889633230847
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SFXN1 RANBP2 ZNF609 TUT4 MYO6 FAM120C DDX60 ZMYM1 MGA PDLIM5

1.66e-05724891036232890
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

CCT3 MYO6 LEMD3 SIPA1L1 PKP2 HSPA9 PDLIM5

1.71e-0531589726777405
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RANBP2 MYH7 MYO1A CCT3 IQGAP2 TTC16 MYH7B PPP1R9A ASPM NAV2 ABCC2 TASOR HSPA9 PHTF1

1.73e-051442891435575683
Pubmed

Functional and Structural Insights into a Vif/PPP2R5 Complex Elucidated Using Patient HIV-1 Isolates and Computational Modeling.

PPP2R5A PPP2R5E

1.94e-05389232847850
Pubmed

Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells.

RANBP2 IGF1R

1.94e-05389224909165
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV3 NAV2

1.94e-05389212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV3 NAV2

1.94e-05389215158073
Pubmed

Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications.

MYOC SPARCL1

1.94e-05389220926826
Pubmed

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

NAV3 NAV2

1.94e-05389212062803
Pubmed

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.

PPP2R5A PPP2R5E

1.94e-05389221878643
Pubmed

IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers.

IGF1R CD34

1.94e-05389229951828
Pubmed

COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children.

MYOC MKX

1.94e-05389236834493
Pubmed

FAM188B enhances cell survival via interaction with USP7.

UBR5 HSPA9 PCM1 KIF7

2.41e-056589429795372
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SFXN1 ZNF609 TUT4 IGF1R TULP4 MYO6 FAM120C PPP1R9A AFF3 NLRC5 DYNC2I1 LRBA NEDD1 PCM1

2.47e-051489891428611215
Pubmed

Genetic Hearing Loss Overview

MYO1A MYO6 DSPP MYO15A

3.23e-057089420301607
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

TUT4 CCT3 UBR5 SIPA1L1 DIAPH2 PCM1

3.25e-0523589630258100
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

RANBP2 CCT3 MYO6 PKP2 MGA HSPA9 PCM1

3.53e-0535389727545878
Pubmed

A human MAP kinase interactome.

RANBP2 CCT3 MYO6 DIAPH2 NAV3 NAV2 CGNL1 MGA

3.60e-0548689820936779
Pubmed

Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system.

CNTN5 CNTN1

3.87e-0548921838307
Pubmed

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.

MYO6 MYO15A

3.87e-05489222105175
Pubmed

Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia.

MYO6 MYO15A

3.87e-05489212966030
Pubmed

Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.

MYH7 MYH7B

3.87e-05489219948655
Pubmed

In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear.

MYO6 DIAPH2

3.87e-05489236689403
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MYO1A DCP1B UBR5 MYO6 RPTN SIPA1L1 PPP1R9A DHX38 KDM3B FEM1A KIF7

5.19e-051005891119615732
Pubmed

The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits.

PPP2R5A PPP2R5E

6.44e-0558928694763
Pubmed

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12.

PPP2R5A PPP2R5E

6.44e-0558928812429
Pubmed

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice.

PPP2R5A PPP2R5E

6.44e-05589215095873
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 FAM171A1 IGF1R DCP1B SIPA1L1 KDM3B NAV2 PKP2 CGNL1 PCM1

7.15e-05861891036931259
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

SLAIN2 RANBP2 DDX60 KDM3B FLG2 MGA

7.31e-0527289631010829
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SFXN1 RANBP2 ZNF609 IGF1R CCT3 TULP4 MYO6 SIPA1L1 PKP2 MGA HSPA9 PDLIM5

7.97e-051247891227684187
Pubmed

Genomics and hearing impairment.

MYO6 MYO15A

9.65e-0568929927480
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RANBP2 ZNF609 UBR5 LRBA MGA TASOR PCM1

1.02e-0441889734709266
Pubmed

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells.

CCT3 UBR5 MGA PDLIM5

1.07e-049589429490077
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

PPP2R5A PPP2R5E PTPRH CCT3 UBR5 MYO6 PPP1R9A DHX38

1.13e-0457389828330616
Pubmed

Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.

PPP2R5A PPP2R5E CCT3

1.18e-043789326811472
Pubmed

Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse.

MYO6 MYO15A

1.35e-04789216962269
Pubmed

Tails of unconventional myosins.

MYO6 MYO15A

1.35e-04789211212352
Pubmed

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

PPP2R5A PPP2R5E

1.35e-0478928703017
Pubmed

Identification of a new family of protein phosphatase 2A regulatory subunits.

PPP2R5A PPP2R5E

1.35e-0478927592815
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

NAV3 NAV2

1.35e-04789225065758
Pubmed

Helios is a key transcriptional regulator of outer hair cell maturation.

MYO6 MYO15A

1.35e-04789230464345
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

SFXN1 RANBP2 UBR5 LRBA HSPA9

1.56e-0419789531620119
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SFXN1 CACNB1 RANBP2 TUT4 FAM120C SIPA1L1 ADGRB2 NAV3 SPARCL1 HSPA9 PCM1

1.57e-041139891136417873
Pubmed

Expression, functional, and structural analysis of proteins critical for otoconia development.

DSPP SPARCL1

1.79e-04889220803598
Pubmed

TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21/FoxM1.

A2M MYH7 HSPA9

1.86e-044389331992359
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DCP1B UBR5 SIPA1L1 PCM1 WIPI2

2.06e-0420989536779422
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

MYO6 SIPA1L1 RLIM TASOR KIF7

2.20e-0421289533853758
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

A2M RANBP2 FAM120C SIPA1L1 NAV3 NEDD1 PCM1

2.23e-0447589731040226
Pubmed

A protein interaction landscape of breast cancer.

UBR5 MYO6 DDX60 NAV2 GOLIM4 ZMYM1 PDLIM5 PCM1

2.25e-0463489834591612
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

PPP2R5A PPP2R5E CCT3

2.27e-044689318782753
Pubmed

Apoptosis Inducing Factor Binding Protein PGAM5 Triggers Mitophagic Cell Death That Is Inhibited by the Ubiquitin Ligase Activity of X-Linked Inhibitor of Apoptosis.

SFXN1 HSPA9

2.30e-04989227218139
Pubmed

The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling.

IGF1R UBR5

2.30e-04989222033112
Pubmed

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression.

PPP2R5A PPP2R5E

2.30e-04989223345399
Pubmed

De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.

PPP2R5A PPP2R5E

2.30e-04989230595372
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

DCP1B TSBP1 SIPA1L1 CNTN5 NAV2 PKP2 MYO15A PHTF1 KIF7

2.41e-0481489923251661
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

SFXN1 CCT3 IQGAP2 UBR5 MGA

2.66e-0422189529991511
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SECISBP2L A2M ZNF609 ERCC4 DHX38 DIAPH2 KDM3B TASOR

2.67e-0465089838777146
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

IRF2BP2 RANBP2 ERCC4 AFF3 MGA

2.72e-0422289537071664
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L TULP4 MYO6 DHX38 CGNL1 MGA TASOR

2.79e-0449389715368895
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PPP2R5E CCT3 IQGAP2 MYO6 FAM120C SIPA1L1 PPP1R9A CGNL1 HSPA9 PDLIM5 PCM1 CNTN1

2.86e-041431891237142655
Pubmed

Secreted factor R-Spondin 2 is involved in refinement of patterning of the mammalian cochlea.

MYO6 RSPO1

2.88e-041089223192966
Pubmed

Rho-family GTPase 1 (Rnd1) is a biomechanical stress-sensitive activator of cardiomyocyte hypertrophy.

MYH7 NEDD1

2.88e-041089230797814
Pubmed

The transcription factor GATA-6 regulates pathological cardiac hypertrophy.

MYH7 ADAMTS3

2.88e-041089220705924
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

CCT3 DCP1B NEDD1 PDLIM5 PCM1

2.95e-0422689525900982
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

SFXN1 IRF2BP2 RANBP2 ZNF609 CCT3 IQGAP2 HSPA9 PCM1

3.10e-0466589830457570
Pubmed

Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival.

MYH7 PCM1

3.51e-041189231286143
Pubmed

Restoring physiological cell heterogeneity in the mesenchyme during tooth engineering.

DSPP CD34

3.51e-041189223319349
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SFXN1 A2M CCT3 MYO6 DDX60 SIPA1L1 SURF6 DHX38 PKP2 FLG2 HSPA9

3.64e-041257891136526897
InteractionAPC interactions

RANBP2 PPP2R5A UBR5 MYO6 FAM120C NAV3 NAV2 PKP2 CGNL1 KIF7

6.82e-063898710int:APC
InteractionBICD1 interactions

RANBP2 UBR5 CGNL1 NEDD1 HSPA9 PDLIM5 PCM1 KIF7

1.26e-05250878int:BICD1
InteractionMAD2L1 interactions

IGF1R ERCC4 UBR5 PPP1R9A KDM3B FLG2 MGA KIF7

1.33e-05252878int:MAD2L1
InteractionARL16 interactions

SFXN1 MYO6 MGA TASOR PCM1

2.97e-0583875int:ARL16
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

1.03e-048892chr9q12
CytobandEnsembl 112 genes in cytogenetic band chr4q22

DSPP SPARCL1 PDLIM5

4.13e-0474893chr4q22
GeneFamilyEF-hand domain containing|S100 fused type protein family

RPTN FLG2

2.18e-0475921350
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R5A PPP2R5E

1.07e-0315592696
GeneFamilyMyosin heavy chains

MYH7 MYH7B

1.07e-03155921098
GeneFamilyWD repeat domain containing

TULP4 DYNC2I1 LRBA NEDD1 WIPI2

1.63e-03262595362
GeneFamilyFibronectin type III domain containing

IGF1R PTPRH CNTN5 CNTN1

1.84e-03160594555
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SECISBP2L FAM171A1 RANBP2 PPP2R5A TUT4 IGF1R PPP2R5E UBR5 SIPA1L1 NAV3 KDM3B TASOR PDLIM5

5.49e-068568813M4500
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 IGF1R SIPA1L1 PPP1R9A AFF3 DIAPH2 NAV2 LRBA

5.87e-09196898ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 IGF1R SIPA1L1 PPP1R9A AFF3 DIAPH2 NAV2 LRBA

6.36e-091988981996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

A2M ADAMTS3 DIAPH2 NAV3 NAV2 SPARCL1 IQCJ-SCHIP1

1.46e-07198897b8bd1ba268480f54451648e01631b615a3401144
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAM171A1 TUT4 UBR5 PPP1R9A DIAPH2 SPARCL1 FAM124B

1.56e-07200897dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A TUT4 PPP1R9A DIAPH2 SPARCL1 FAM124B

1.56e-07200897a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 MYO6 DDX60 CD34 AFF3 NLRC5

2.08e-06187896f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 MYO6 DDX60 CD34 AFF3 NLRC5

2.42e-06192896c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 DCP1B PPP1R9A PKP2 IQCJ-SCHIP1 PDLIM5

2.49e-06193896dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A SPARCL1 FAM124B

2.49e-06193896af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A NAV3 FAM124B

2.49e-06193896e1d546165dcc2392f540162206852c4717d7306f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF2BP2 TULP4 MYO6 NAV2 MGA PCM1

2.64e-061958967796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellILEUM-non-inflamed-(7)_ACKR1+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

A2M FAM171A1 TNFSF13B CD34 SPARCL1 SPINK5

2.89e-06198896f8a6a75c9f2fbe32a22b14b6a029411c73c09f68
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SLAIN2 PPP2R5E IQGAP2 MYO6 RLIM CNTN1

2.97e-0619989653ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SLAIN2 PPP2R5E IQGAP2 MYO6 RLIM DYNC2I1

2.97e-06199896fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 IGF1R UBR5 PPP1R9A AFF3 LRBA

2.97e-0619989694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A PPP1R9A SPARCL1 IQCJ-SCHIP1 FAM124B

3.06e-06200896eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A MYO6 CD34 SPARCL1 FAM124B

3.06e-06200896b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A TUT4 PPP1R9A SPARCL1 FAM124B

3.06e-06200896b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A MYO6 CD34 AFF3 SPARCL1

3.06e-06200896432384faeade8e609154fab3d96c955a8ec868dd
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

A2M TNFSF13B RNF25 FLG2 SPINK5

8.22e-06137895dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SECISBP2L SLAIN2 ZNF609 ADAMTS3 SPINK5

1.91e-05163895d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

FAM171A1 ADAMTS3 CD34 NAV3 SPARCL1

2.47e-05172895c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M IGF1R DDX60 TNFSF13B GOLIM4

2.47e-05172895d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellIonocyte-iono-2|World / Class top

PPP2R5A NAPEPLD SURF6 AFF3 CGNL1

2.54e-05173895e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MYO6 PPP1R9A NAV2 IQCJ-SCHIP1 CGNL1

2.99e-05179895a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

3.07e-0518089530cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 PPP1R9A SPARCL1 MYO15A CNTN1

3.32e-05183895262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 PPP1R9A SPARCL1 MYO15A CNTN1

3.32e-05183895c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellIPF-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

TNFSF13B PPP1R9A AFF3 GOLIM4 FAM124B

3.32e-051838959b507547e6adf78e46e7f542cd9958224ec5826a
ToppCellEndothelial-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

A2M FAM171A1 CD34 SPARCL1 FAM124B

3.68e-05187895fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

3.77e-0518889573f6ec915934154f435a376cb274b058ff7c5f35
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M CD34 AFF3 NAV3 SPARCL1

3.77e-05188895117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

A2M FAM171A1 CD34 SPARCL1 FAM124B

3.77e-051888950824d567356d360fd8e78e840c30529c139f98a1
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

IGF1R UBR5 MYO6 NAV2 CGNL1

3.77e-05188895b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

FAM171A1 CD34 NAV3 SPARCL1 IQCJ-SCHIP1

3.87e-05189895c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

3.87e-0518989571397e993a77d70b2eeede240bdfc7660b558987
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 IQGAP2 CD34 PPP1R9A HSPA9

3.87e-05189895533685a921a65d84107d8d33c43b4fffde019143
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

3.87e-051898954eea4759520c312bd17a681034d8074e47093d2b
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

A2M FAM171A1 CD34 SPARCL1 FAM124B

3.87e-0518989504b565855f58ca0f343904d04be657b66e109076
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 IQGAP2 CD34 PPP1R9A HSPA9

3.87e-05189895dca56ab02bf0505f9a352ff907edaef30906d854
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 IQGAP2 CD34 PPP1R9A HSPA9

3.97e-05190895a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

3.97e-05190895474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

A2M FAM171A1 CD34 SPARCL1 FAM124B

4.07e-05191895f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.07e-0519189539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SECISBP2L MYO6 PPP1R9A NAV2 CGNL1

4.07e-05191895d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.07e-05191895ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.17e-05192895bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV3 NAV2 CNTN1

4.17e-051928955105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

4.17e-0519289504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

MYH7 MYH7B PPP1R9A PKP2 PDLIM5

4.17e-05192895ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

4.17e-05192895c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

MYO6 PPP1R9A AFF3 NAV2 CGNL1

4.17e-05192895efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.17e-051928950ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A FAM124B

4.27e-05193895e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellPND03-Epithelial-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH7 PPP1R9A NAV2 PKP2 SPINK5

4.27e-051938955dfa69a680a0859900141c40a446d217aaa747d3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH7 PPP1R9A NAV2 PKP2 SPINK5

4.27e-05193895ebea35704ac5d21e947ae094313cf2a5205e7014
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

4.27e-0519389502f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A FAM124B

4.27e-051938956e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A AFF3

4.27e-05193895aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 SPARCL1 CGNL1 MYO15A CNTN1

4.27e-05193895f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A CD34 PPP1R9A AFF3

4.27e-05193895c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 PPP2R5A MYO6 CD34 AFF3

4.27e-051938955122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IGF1R MYO6 PPP1R9A CGNL1 LRBA

4.27e-051938953866667dd221612589ae50f5c52f73a183a49ce6
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 MYO6 CD34 AFF3 NLRC5

4.27e-05193895a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TUT4 UBR5 PPP1R9A LRBA PCM1

4.27e-05193895e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 SPARCL1 CGNL1 MYO15A CNTN1

4.27e-051938954ccf984baebbb13ae916727137ce593fda7514a2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.38e-0519489581713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 MKX NAV3 NAV2 CNTN1

4.38e-05194895c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M FAM171A1 AFF3 NAV3 SPARCL1

4.38e-0519489571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO6 PPP1R9A AFF3 NAV2 CGNL1

4.38e-0519489553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 IGF1R CD34 PPP1R9A FAM124B

4.38e-051948950b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.38e-05194895e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 MKX SPARCL1 PDLIM5

4.38e-051948955c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

MYH7B PPP1R9A PKP2 IQCJ-SCHIP1 PDLIM5

4.38e-05194895c3535f7cc0076653c72db582047cff053c322397
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 MKX SPARCL1 PDLIM5

4.38e-05194895ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 MKX SPARCL1 PDLIM5

4.38e-05194895ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M AFF3 NAV2 PDLIM5 CNTN1

4.38e-05194895627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 MYH7B PPP1R9A PKP2 PDLIM5

4.49e-05195895f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 MYH7B PPP1R9A PKP2 PDLIM5

4.49e-0519589575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM171A1 MYO6 PPP1R9A CGNL1 LRBA

4.49e-051958956477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 AFF3 NAV3 NAV2 CNTN1

4.49e-051958953c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellILEUM-inflamed-(6)_ILC3|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IRF2BP2 TNFSF13B PPP1R9A AFF3 FAM124B

4.49e-05195895c6968da7d2b60c2163e1ff0ffa41340e1ec1d2ed
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF2BP2 MYO6 NAV2 MGA PCM1

4.49e-051958953e519cffa6144a62b06124642a14c9ff39b76554
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO6 PPP1R9A NAV2 CGNL1 LRBA

4.49e-051958959406866f99555198a9be311fbd65751b70f35446
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

LEMD3 ASPM DIAPH2 MGA TASOR

4.60e-05196895b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

A2M MYO6 TTC16 KIF19 NLRC5

4.60e-05196895af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M NAV3 NAV2 IQCJ-SCHIP1 CNTN1

4.71e-05197895f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SLAIN2 IRF2BP2 PPP2R5E RLIM DYNC2I1

4.94e-0519989561b1ed2db71b96157b92b7535d1955a4033098da
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD34 NAV3 SPARCL1 CGNL1 CNTN1

4.94e-05199895103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD34 NAV3 SPARCL1 CGNL1 CNTN1

4.94e-051998959846d6a31635fde759d55674631c11ab9270a603
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD34 NAV3 SPARCL1 CGNL1 CNTN1

4.94e-0519989583383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

SLAIN2 PPP2R5E MYO6 RLIM CNTN1

4.94e-05199895d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

A2M CD34 SPARCL1 CGNL1 FAM124B

5.06e-052008955ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A MYO6 SPARCL1 PDLIM5

5.06e-0520089581e76508c9050d533853d5fd2f3097b27613d836
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

FAM171A1 TUT4 PPP1R9A DIAPH2 FAM124B

5.06e-052008953b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A SPARCL1 IQCJ-SCHIP1 FAM124B

5.06e-05200895f15fffefe372005c33e31845982e2d2714ac26af
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

A2M CD34 KIF19 SPARCL1 PDLIM5

5.06e-052008959c1b30fa96565515a7160f439cadcd51482c41e9
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M MYOC NAV3 NAV2 SPARCL1

5.06e-05200895b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A MYO6 CD34 FAM124B

5.06e-05200895a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 PPP2R5A MYO6 CD34 FAM124B

5.06e-052008951d105eeda5a2c51f9a4654ffc79b7e2348ad593b
DrugSparteine (-) [90-39-1]; Up 200; 17uM; PC3; HT_HG-U133A

A2M CACNB1 CNTN5 NAV3 ABCC2 PDLIM5 JHY SPINK5

8.76e-071998684568_UP
Drugformycin triphosphate

MYH7 MYO1A MYO6 MYH7B MYO15A

1.40e-0651865CID000122274
Drugpurealin

MYH7 MYO1A MYO6 MYH7B MYO15A

2.68e-0658865CID006419303
DrugChloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A

A2M CACNB1 IGF1R PTPRH NAV3 ABCC2 PDLIM5

7.00e-061878674589_UP
DrugMethylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A

MYOC CD34 AFF3 DIAPH2 PDLIM5 CNTN1 SPINK5

9.52e-061968676785_UP
Drugnocodazole

RANBP2 MYH7 PPP2R5A PPP2R5E MYO6 MYH7B GOLIM4 GRAMD4 PCM1 CNTN1

1.27e-054778610CID000004122
DiseaseSPARC-like protein 1 measurement

DSPP DHX38 SPARCL1

4.27e-076833EFO_0008289
DiseaseLeft ventricular noncompaction

MYH7 MYH7B PKP2

7.64e-0614833C1960469
Diseaseneutropenia, leukopenia, chemotherapy-induced cytotoxicity measurement

TNFSF13B NLRC5

7.82e-062832EFO_0004233, EFO_0010978, MONDO_0001475
Diseaseblood lead measurement, bone density

NAV2 WIPI2

2.34e-053832EFO_0003923, EFO_0007040
Diseasecardiomyopathy (implicated_via_orthology)

MYH7 MYH7B SPARCL1 PDLIM5

4.90e-0571834DOID:0050700 (implicated_via_orthology)
Diseaseatrial fibrillation

MYH7 IGF1R CNTN5 NAV2 PKP2 CGNL1 PCM1

8.58e-05371837EFO_0000275
Diseasesensorineural hearing loss (is_implicated_in)

MYO1A MYO6 MYO15A

1.10e-0433833DOID:10003 (is_implicated_in)
Diseasecorpus callosum anterior volume measurement

NAV3 NAV2 IQCJ-SCHIP1

1.82e-0439833EFO_0010295
DiseaseQRS duration

IGF1R UBR5 MYH7B SIPA1L1 PDLIM5 CNTN1

1.98e-04298836EFO_0005055
Diseasemyopathy (implicated_via_orthology)

MYH7 MYH7B PDLIM5

3.39e-0448833DOID:423 (implicated_via_orthology)
Diseaseheart disease (is_marker_for)

A2M MYH7

3.47e-0410832DOID:114 (is_marker_for)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH7 MYH7B

3.47e-0410832DOID:0111596 (implicated_via_orthology)
Diseasemonokine induced by gamma interferon measurement

ERCC6L2 FAM124B PHTF1

4.29e-0452833EFO_0008236
Diseasedistal myopathy (implicated_via_orthology)

MYH7 MYH7B

5.07e-0412832DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH7 MYH7B

5.07e-0412832DOID:2106 (implicated_via_orthology)
DiseaseCommon variable immunodeficiency

IRF2BP2 LRBA

5.98e-0413832cv:C0009447
Diseaserostral anterior cingulate cortex volume measurement

SFXN1 CGNL1

5.98e-0413832EFO_0010327
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

5.98e-0413832DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH7 MYH7B

8.02e-0415832DOID:0050646 (implicated_via_orthology)
DiseaseParoxysmal atrial fibrillation

MYH7 IGF1R NAV2 PKP2

9.99e-04156834C0235480
Diseasefamilial atrial fibrillation

MYH7 IGF1R NAV2 PKP2

9.99e-04156834C3468561
DiseasePersistent atrial fibrillation

MYH7 IGF1R NAV2 PKP2

9.99e-04156834C2585653
DiseaseAtrial Fibrillation

MYH7 IGF1R NAV2 PKP2

1.10e-03160834C0004238
Diseasejuvenile idiopathic arthritis

TSBP1 AFF3 PHTF1

1.20e-0374833EFO_0002609
Diseaseanthropometric measurement

IGF1R ADAMTS3 MKX PDLIM5

1.31e-03168834EFO_0004302
Diseaseage at menarche

IGF1R MYO6 CNTN5 AFF3 KDM3B PSMG3-AS1 JHY

1.43e-03594837EFO_0004703
Diseasecoagulation factor measurement

ASPM CNTN1

1.44e-0320832EFO_0004634
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B PDLIM5

1.51e-0380833DOID:12930 (implicated_via_orthology)
Diseasetotal blood protein measurement

ZNF609 IQGAP2 TNFSF13B CD34 DHX38 AFF3

1.69e-03449836EFO_0004536
Diseasehypertrophic cardiomyopathy (is_implicated_in)

MYH7 MYH7B

1.74e-0322832DOID:11984 (is_implicated_in)
Diseasevenous thromboembolism

SFXN1 IQGAP2 LEMD3 TNFSF13B SURF6 NAV2

1.91e-03460836EFO_0004286
Diseasedrug-induced liver injury

TSBP1 LRBA

2.07e-0324832EFO_0004228
DiseaseDwarfism

ERCC4 KDM3B

2.25e-0325832C0013336
DiseaseLeft ventricular mass to end-diastolic volume ratio

IGF1R SIPA1L1

2.25e-0325832EFO_0010556
DiseaseMicronuclei, Chromosome-Defective

ERCC4 PPP2R5E

2.43e-0326832C1449861
DiseaseMicronuclei, Genotoxicant-Induced

ERCC4 PPP2R5E

2.43e-0326832C1449862
Diseasehearing impairment

MYO1A DSPP MYO15A

2.69e-0398833C1384666
Diseasesmoking behavior

IGF1R ERCC4 ADGRB2 NAV3 NAV2

2.78e-03341835EFO_0004318

Protein segments in the cluster

PeptideGeneStartEntry
RQKRSQSSSQFRSQG

PPP2R5E

26

Q16537
ANGTQQRSRKCSVAG

ADGRB2

436

O60241
SDGQQRATQQGSLRT

AFF3

156

P51826
LRQNRLGSSKSGDNS

CACNB1

176

Q02641
KGQAQASNGAERRSQ

GRAMD4

146

Q6IC98
AGATNRSNTNGNTDK

DSPP

146

Q9NZW4
GAQVNTQGEISNKRS

ANKRD61

156

A6NGH8
GRSNKRSAGNRAANE

DIAPH2

21

O60879
FNSVNVNGQRGENSK

ASPM

281

Q8IZT6
SQRQKDNGCFRSSGS

A2M

1071

P01023
AENSRGKNSFRGQLQ

CNTN5

371

O94779
GSSQQKNSGFRRSDD

RANBP2

1116

P49792
GNAKTVRNDNSSRFG

MYH7

231

P12883
QQQHRSGGRGNKTRN

LEMD3

51

Q9Y2U8
SGGRGNKTRNSNNNN

LEMD3

56

Q9Y2U8
RLGRQGNLSSSGNQE

FLG2

161

Q5D862
GNLSSSGNQEGSQKR

FLG2

166

Q5D862
SARKGRGDALSLQQN

FAM171A1

751

Q5VUB5
SQRNQVKISRSNSEG

JHY

611

Q6NUN7
QRAQAGSNQSRGKCG

PSMG3-AS1

81

Q96PY0
VNKRSVNVNAASGGV

NEDD1

321

Q8NHV4
RNEGGNSESSLKNRS

MGA

806

Q8IWI9
SFGNAKTVRNDNSSR

MYO15A

1356

Q9UKN7
GNAKTIRNNNSSRFG

MYO1A

146

Q9UBC5
NTGERSNTGERSNDK

SPINK5

831

Q9NQ38
RGSLNGGNRVNNAKN

KIAA1109

2626

Q2LD37
ESQNGEHRNRGASSK

DYNC2I1

291

Q8WVS4
ENNTASKRHVGRQAG

DDX60

946

Q8IY21
RQSKGDINTRNNGER

IGF1R

471

P08069
GNAKTLRNDNSSRFG

MYH7B

276

A7E2Y1
SQGRATAANNKRQLS

PCM1

121

Q15154
NNTRGNANKTQKDTG

PCM1

711

Q15154
TSSNRKNQLDTNGRR

PCM1

1236

Q15154
TLENGSNKGESAANR

MKX

281

Q8IYA7
SKVQGASNLNRRSQS

NAV3

261

Q8IVL0
SNAGRKTSLDGSQNQ

NAV3

1106

Q8IVL0
SEKSGQLRQGSAQSQ

KIF7

986

Q2M1P5
GARTAQLRKANDQSG

MYOC

31

Q99972
KGSRSQASGENSRNS

KDM3B

451

Q7LBC6
GKQSIRSQALGNQNS

LRBA

2036

P50851
ALQRRQEKSSQQNSG

ABCC2

256

Q92887
AEGQRRGSQGDSKQQ

PDLIM5

221

Q96HC4
QRQATKDAGQISGLN

HSPA9

201

P38646
QESDGQRKGAQSRSL

NLRC5

831

Q86WI3
AQETLNKGRQDSNSR

GOLIM4

96

O00461
LAGSERASQTQNRGQ

KIF19

251

Q2TAC6
GTSRGVQNASRTQNL

DCP1B

341

Q8IZD4
GANLRQRSAQQAGSK

ADAMTS3

1126

O15072
RSQRNQGKRSQGHSL

FAM124B

281

Q9H5Z6
QTLKSRAAGSAQGNN

CGNL1

586

Q0VF96
AENNRGKANSTGTLV

CNTN1

486

Q12860
QGRSRSQVNGNSGAL

FAM120C

1026

Q9NX05
EQGAQVNRRSAKGNT

FEM1A

171

Q9BSK4
QNQTTLGSSRAKLGN

C1RL

241

Q9NZP8
RNNDNSRNTDDKRNG

ERCC6L2

951

Q5T890
ANGANGSKAVARTAR

IRF2BP2

341

Q7Z5L9
NRGAQENGTGQATSR

CD34

356

P28906
KQNEQLRSRSGAVQG

SLAIN2

26

Q9P270
NGNRLGESANAAKQA

SFXN1

211

Q9H9B4
AGGQINSDQRRNLGS

IQGAP2

1126

Q13576
QQSRSLGAQSSKAGE

SPATA31A7

936

Q8IWB4
KTRGGSTTANNRRSQ

NAV2

296

Q8IVL1
GAGSRRRKGQQQQQQ

RSPO1

236

Q2MKA7
DRQNTQSDIGGSGKS

SIPA1L1

1186

O43166
RESGRKVQSGNINAA

CCT3

16

P49368
EKNQTFSRGGRQTEQ

SECISBP2L

326

Q93073
FSRGGRQTEQRNNSQ

SECISBP2L

331

Q93073
VNNGGTERGSNNARL

PRR32

146

B1ATL7
NQDNTEVKGASRAAG

WIPI2

21

Q9Y4P8
QQARTRAGKTQGSET

SURF6

26

O75683
GQARTNSTSAQKNER

IQCJ-SCHIP1

321

B3KU38
NNSRGEAIISGKQRS

TASOR

656

Q9UK61
KRSQGSSQFRSQGSQ

PPP2R5A

36

Q15172
QQSRSLGAQSSKAGE

SPATA31A3

936

Q5VYP0
SQLAQGRGAAQRSDN

TULP4

966

Q9NRJ4
QQSRSLGAQSSKAGE

SPATA31A1

936

Q5TZJ5
RKTVNGDGSRENGNN

PHTF1

166

Q9UMS5
QQSRSLGAQSSKAGE

SPATA31A5

936

Q5VU36
NRSSKHSQGLRDQGN

SPARCL1

176

Q14515
GTRSNQQRLGETQKA

RNF25

321

Q96BH1
SNDKGSGDQSAAQRR

RLIM

6

Q9NVW2
RQTGNTTRSGQRGNQ

RLIM

106

Q9NVW2
TRAGANSKGRRGSQN

ZNF609

401

O15014
NSKGRRGSQNSSEHR

ZNF609

406

O15014
SQANANQRSGRAGRT

DHX38

846

Q92620
QRRNSSKTRATQGQG

TTC16

716

Q8NEE8
STDTRKAGGQEQNGT

ERCC4

666

Q92889
LRGNDQSVSSVNKGN

ZMYM1

571

Q5SVZ6
NKSHGGRTSQQERGQ

RPTN

91

Q6XPR3
GEGNSSQNSRNKRAV

TNFSF13B

121

Q9Y275
CGGTARSQNSREENK

TSBP1

236

Q5SRN2
AGSAQQQGDQSIRTR

TUT4

1401

Q5TAX3
GKNGINSSRETRNAT

PTPRH

191

Q9HD43
QQTLARKGRSSVGNG

PKP2

61

Q99959
NNDGSKLNSNSGAGR

UBR5

86

O95071
AFGNAKTVRNNNSSR

MYO6

191

Q9UM54
VRKRQNSARNSGASD

NAPEPLD

21

Q6IQ20
SQQSRGRKYGSNVNR

PPP1R9A

51

Q9ULJ8