Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	interleukin-1, type II receptor binding	ERAP1 IL1RN	2.58e-05	2	102	2	GO:0005151
GeneOntologyMolecularFunction	cell adhesion molecule binding	SPTAN1 ITGA3 ITGAV DST PTPRO NECTIN1 CGN GIGYF2 KIRREL1 MACF1 CTNNA2 SNX2	5.49e-05	599	102	12	GO:0050839
GeneOntologyMolecularFunction	microtubule minus-end binding	CEP290 MACF1 NIN	5.63e-05	15	102	3	GO:0051011
GeneOntologyMolecularFunction	quaternary ammonium group binding	ABCA1 CHRM3 PITPNM1 HACL1	8.88e-05	46	102	4	GO:0050997
GeneOntologyMolecularFunction	lipid transfer activity	ABCA1 APOB STAR PITPNM1	2.06e-04	57	102	4	GO:0120013
GeneOntologyMolecularFunction	small GTPase binding	ABCA1 RANBP3 NCF2 NPC1L1 DENND5A FGD6 USP33 PLCE1	2.42e-04	321	102	8	GO:0031267
GeneOntologyMolecularFunction	cholesterol transfer activity	ABCA1 APOB STAR	2.42e-04	24	102	3	GO:0120020
GeneOntologyMolecularFunction	sterol transfer activity	ABCA1 APOB STAR	2.74e-04	25	102	3	GO:0120015
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	CHRM3 PLCG2 PLCE1	3.09e-04	26	102	3	GO:0004435
GeneOntologyMolecularFunction	phospholipase C activity	CHRM3 PLCG2 PLCE1	4.29e-04	29	102	3	GO:0004629
GeneOntologyMolecularFunction	lipid transporter activity	ABCA1 ABCA13 APOB STAR PITPNM1 NPC1L1	5.11e-04	196	102	6	GO:0005319
GeneOntologyMolecularFunction	GTPase binding	ABCA1 RANBP3 NCF2 NPC1L1 DENND5A FGD6 USP33 PLCE1	5.19e-04	360	102	8	GO:0051020
GeneOntologyMolecularFunction	microtubule binding	CEP290 DST SUN2 CGN MACF1 DNAI7 NIN	1.03e-03	308	102	7	GO:0008017
GeneOntologyCellularComponent	endocytic vesicle	ABCA1 STAB2 NCF2 APOB ECPAS ITGAV PIK3R4 CCL2 RAB13	1.02e-04	384	101	9	GO:0030139
GeneOntologyCellularComponent	lamellipodium	ITGAV PTPRO CTNNA2 FGD6 RAB13 SNX2 PLCE1	1.27e-04	230	101	7	GO:0030027
GeneOntologyCellularComponent	cell leading edge	ITGAV DST PTPRO MACF1 CTNNA2 PLCG2 FGD6 RAB13 SNX2 PLCE1	1.54e-04	500	101	10	GO:0031252
GeneOntologyCellularComponent	perinuclear region of cytoplasm	ABCA1 USP29 PTPN22 ITGA3 TSPAN1 CASK DST CCL2 KIRREL1 PLCG2 UGT2B28 COPS5 FKBP4 USP33	1.58e-04	934	101	14	GO:0048471
GeneOntologyCellularComponent	axon	IL31RA SPTA1 SPTAN1 ITGA3 CHRM3 NEFL DST PTPRO NECTIN1 CCL2 CTNNA2 FKBP4 NIN	3.57e-04	891	101	13	GO:0030424
GeneOntologyCellularComponent	cell cortex	ZHX3 SPTA1 SPTAN1 DST PDE4DIP MACF1 CD302 CTNNA2	4.39e-04	371	101	8	GO:0005938
GeneOntologyCellularComponent	rod photoreceptor outer segment	CEP290 GUCY2F	8.14e-04	9	101	2	GO:0120200
GeneOntologyCellularComponent	spectrin	SPTA1 SPTAN1	8.14e-04	9	101	2	GO:0008091
GeneOntologyCellularComponent	inner dynein arm	DNAH2 DNAI7	1.01e-03	10	101	2	GO:0036156
GeneOntologyCellularComponent	growth cone	ITGA3 NEFL PTPRO NECTIN1 FKBP4 NIN	1.22e-03	245	101	6	GO:0030426
GeneOntologyCellularComponent	distal axon	ITGA3 CHRM3 NEFL PTPRO NECTIN1 CCL2 FKBP4 NIN	1.23e-03	435	101	8	GO:0150034
GeneOntologyCellularComponent	site of polarized growth	ITGA3 NEFL PTPRO NECTIN1 FKBP4 NIN	1.44e-03	253	101	6	GO:0030427
GeneOntologyCellularComponent	basal plasma membrane	ABCA1 ITGA3 CHRM3 CASK SLC6A12 DST CTNNA2	1.66e-03	354	101	7	GO:0009925
GeneOntologyCellularComponent	cuticular plate	SPTA1 SPTAN1	1.74e-03	13	101	2	GO:0032437
MousePheno	abnormal kidney cortex morphology	ABCA1 SPTA1 CEP290 PTPN22 NCF2 ITGA3 BBS10 PTPRO KIRREL1 PLCG2 BICC1	5.10e-06	324	87	11	MP:0000521
MousePheno	abnormal renal corpuscle morphology	ABCA1 SPTA1 PTPN22 NCF2 ITGA3 BBS10 PTPRO KIRREL1 PLCG2 BICC1	1.35e-05	293	87	10	MP:0002827
MousePheno	abnormal nephron morphology	ABCA1 SPTA1 CEP290 PTPN22 NCF2 ITGA3 BBS10 PTPRO KIRREL1 PLCG2 BICC1	6.45e-05	426	87	11	MP:0003881
Domain	Spectrin	SPTA1 SPTAN1 DST MACF1	6.85e-06	23	102	4	PF00435
Domain	Spectrin_repeat	SPTA1 SPTAN1 DST MACF1	1.79e-05	29	102	4	IPR002017
Domain	SPEC	SPTA1 SPTAN1 DST MACF1	2.68e-05	32	102	4	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTAN1 DST MACF1	2.68e-05	32	102	4	IPR018159
Domain	SH3	SPTA1 SPTAN1 NCF2 CASK DST MACF1 PLCG2	1.83e-04	216	102	7	PS50002
Domain	SH3_domain	SPTA1 SPTAN1 NCF2 CASK DST MACF1 PLCG2	2.05e-04	220	102	7	IPR001452
Domain	-	DST MACF1	4.37e-04	6	102	2	3.90.1290.10
Domain	GAR	DST MACF1	4.37e-04	6	102	2	PS51460
Domain	EFhand_Ca_insen	SPTA1 SPTAN1	4.37e-04	6	102	2	PF08726
Domain	GAS2	DST MACF1	4.37e-04	6	102	2	PF02187
Domain	EF-hand_Ca_insen	SPTA1 SPTAN1	4.37e-04	6	102	2	IPR014837
Domain	-	DST MACF1	4.37e-04	6	102	2	3.30.920.20
Domain	GAS_dom	DST MACF1	4.37e-04	6	102	2	IPR003108
Domain	GAS2	DST MACF1	4.37e-04	6	102	2	SM00243
Domain	Plectin	DST MACF1	6.09e-04	7	102	2	PF00681
Domain	Plectin_repeat	DST MACF1	6.09e-04	7	102	2	IPR001101
Domain	PLEC	DST MACF1	6.09e-04	7	102	2	SM00250
Domain	PTPc	PTPN22 PTPRG PTPRO	9.91e-04	36	102	3	SM00194
Domain	EF-hand-dom_pair	SPTA1 SPTAN1 DST MACF1 PLCG2 PLCE1 NIN	1.00e-03	287	102	7	IPR011992
Domain	TYR_PHOSPHATASE_PTP	PTPN22 PTPRG PTPRO	1.25e-03	39	102	3	PS50055
Domain	PTPase_domain	PTPN22 PTPRG PTPRO	1.45e-03	41	102	3	IPR000242
Domain	Y_phosphatase	PTPN22 PTPRG PTPRO	1.45e-03	41	102	3	PF00102
Domain	ABC_A	ABCA1 ABCA13	1.88e-03	12	102	2	IPR026082
Domain	SH3_1	SPTA1 SPTAN1 NCF2 DST PLCG2	2.06e-03	164	102	5	PF00018
Domain	P-loop_NTPase	ABCA1 ERCC3 ERCC6 ABCA13 DNAH2 MCM6 MSH3 DHX33 CASK SAMD9L PARPBP RAB13	2.25e-03	848	102	12	IPR027417
Domain	-	ABCA1 ERCC3 ERCC6 ABCA13 DNAH2 MCM6 MSH3 DHX33 CASK SAMD9L RAB13	2.51e-03	746	102	11	3.40.50.300
Domain	EF-hand_like	PLCG2 PLCE1	2.96e-03	15	102	2	PF09279
Domain	PI-PLC-Y	PLCG2 PLCE1	2.96e-03	15	102	2	PF00387
Domain	PLCYc	PLCG2 PLCE1	2.96e-03	15	102	2	SM00149
Domain	Spectrin_alpha_SH3	SPTA1 SPTAN1	2.96e-03	15	102	2	IPR013315
Domain	PLipase_C_Pinositol-sp_Y	PLCG2 PLCE1	2.96e-03	15	102	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCG2 PLCE1	2.96e-03	15	102	2	PS50008
Domain	PI-PLC_fam	PLCG2 PLCE1	2.96e-03	15	102	2	IPR001192
Domain	PLC_EF-hand-like	PLCG2 PLCE1	2.96e-03	15	102	2	IPR015359
Domain	-	SPTA1 SPTAN1 DST MACF1 PLCE1 NIN	3.09e-03	261	102	6	1.10.238.10
Domain	Integrin_alpha_C_CS	ITGA3 ITGAV	3.37e-03	16	102	2	IPR018184
Domain	PTPc_motif	PTPN22 PTPRG PTPRO	4.12e-03	59	102	3	SM00404
Domain	Tyr_Pase_cat	PTPN22 PTPRG PTPRO	4.12e-03	59	102	3	IPR003595
Domain	Integrin_alpha-2	ITGA3 ITGAV	4.27e-03	18	102	2	IPR013649
Domain	PI-PLC-X	PLCG2 PLCE1	4.27e-03	18	102	2	PF00388
Domain	INTEGRIN_ALPHA	ITGA3 ITGAV	4.27e-03	18	102	2	PS00242
Domain	PLCXc	PLCG2 PLCE1	4.27e-03	18	102	2	SM00148
Domain	Integrin_alpha2	ITGA3 ITGAV	4.27e-03	18	102	2	PF08441
Domain	Integrin_alpha	ITGA3 ITGAV	4.27e-03	18	102	2	IPR000413
Domain	Int_alpha	ITGA3 ITGAV	4.75e-03	19	102	2	SM00191
Domain	Int_alpha_beta-p	ITGA3 ITGAV	4.75e-03	19	102	2	IPR013519
Domain	PIPLC_X_DOMAIN	PLCG2 PLCE1	4.75e-03	19	102	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCG2 PLCE1	4.75e-03	19	102	2	IPR000909
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	POMGNT1 SLC39A10 COG3 ITGAV PIK3R4 DST ZFYVE9 LRIG1 SUN2 EMC2 SNX2 USP33	3.13e-08	504	102	12	34432599
Pubmed	RGD-containing ankyrin externalized onto the cell surface triggers αVβ3 integrin-mediated erythrophagocytosis.	SPTA1 SPTAN1 ITGAV	2.44e-07	5	102	3	21406181
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	APOB ITGA3 SLC39A10 CASK PTPRG NECTIN1 KIRREL1 FGD6 RAB13 IPMK ARAP2	9.49e-07	569	102	11	30639242
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RANBP3 SPTAN1 PIK3R4 KIAA1671 DST TCERG1 CGN GIGYF2 MACF1 FGD6 SNX2 BICC1 ARAP2	1.48e-06	861	102	13	36931259
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SPTAN1 CEP290 PTPN22 SLC39A10 CASK KIAA1671 NEFL ZFYVE9 PTPRG SUN2 CGN KIRREL1 FKBP4 NIN	2.39e-06	1049	102	14	27880917
Pubmed	alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus.	ERCC3 ERCC6 SPTA1 SPTAN1	3.02e-06	34	102	4	16889989
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	ZHX3 CCDC30 CEP290 MSH3 PP2D1 CHRNA1 SAMD9L GOLPH3L FGD6 SNX2 BICC1	5.69e-06	686	102	11	29987050
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ERCC3 RANBP3 MCM6 MSH3 ECPAS CASK TCERG1 MED23 COPS5 SNX2	6.12e-06	560	102	10	35241646
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	CEP290 PDE4DIP NIN	6.86e-06	13	102	3	17920017
Pubmed	Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.	APOB NPC1L1	8.52e-06	2	102	2	18031309
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	8.52e-06	2	102	2	11002341
Pubmed	Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.	ABCA1 APOB	8.52e-06	2	102	2	28694219
Pubmed	Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: implications for oxidative stress-impaired reverse cholesterol transport.	ABCA1 STAR	8.52e-06	2	102	2	24269887
Pubmed	Binding of brain spectrin to the 70-kDa neurofilament subunit protein.	SPTAN1 NEFL	8.52e-06	2	102	2	3121319
Pubmed	αII-spectrin regulates invadosome stability and extracellular matrix degradation.	SPTA1 SPTAN1	8.52e-06	2	102	2	25830635
Pubmed	PLCε cooperates with the NF-κB pathway to augment TNFα-stimulated CCL2/MCP1 expression in human keratinocyte.	CCL2 PLCE1	8.52e-06	2	102	2	21951843
Pubmed	Allele polymorphisms of tumor integrins correlate with peritoneal carcinosis capability of gastric cancer cells in radically resected patients.	ITGA3 ITGAV	8.52e-06	2	102	2	20926544
Pubmed	Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium.	ABCA1 APOB	8.52e-06	2	102	2	30076206
Pubmed	Integrators of the cytoskeleton that stabilize microtubules.	NEFL DST	8.52e-06	2	102	2	10428034
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	SPTAN1 DHX33 PITPNM1 DST GIGYF2 MACF1 CTNNA2 SOS1	8.80e-06	347	102	8	17114649
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ERCC3 ERCC6 SPTAN1 MCM6 MSH3 DHX33 NMD3 PIK3R4 NAA35 DST TCERG1 MACF1 AKAP10 PLCG2 RAB13	9.54e-06	1353	102	15	29467282
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	MAGEB1 ABCA1 RANBP3 DST LRIG1 PDE4DIP USP33 NIN	1.22e-05	363	102	8	14691545
Pubmed	A human MAP kinase interactome.	RIPK1 SPTAN1 CEP290 DST TCERG1 GIGYF2 MACF1 COPS5 SOS1	1.37e-05	486	102	9	20936779
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	IL31RA POMGNT1 APOB ITGA3 COG3 PDE4DIP RBM5 MACF1 CTNNA2 EMC2 RAB13 SNX2 BICC1	1.40e-05	1061	102	13	33845483
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	MCM6 ECPAS CASK KIAA1671 NEFL TCERG1 CGN RBM5 FGD6 FKBP4 ARAP2 SOS1	1.60e-05	916	102	12	32203420
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	SLC39A10 ITGAV CASK DST PTPRG KIRREL1 CTNNA2 RAB13	1.60e-05	377	102	8	38117590
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTA1 SPTAN1 ITGA3	1.94e-05	18	102	3	12119179
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ERCC6 ABCA13 SPTAN1 APOB SLC39A10 CHRM3 DST KIRREL1 PARPBP	2.10e-05	513	102	9	25798074
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SPTAN1 CEP290 MSH3 CASK PIK3R4 NEFL DST TCERG1 PDE4DIP MACF1 DNAI7 COPS5 USP33 SOS1	2.36e-05	1285	102	14	35914814
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	2.55e-05	3	102	2	12399109
Pubmed	Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells.	ITGA3 ITGAV	2.55e-05	3	102	2	27974569
Pubmed	Co- and post-transcriptional regulation of Rbm5 and Rbm10 in mouse cells as evidenced by tissue-specific, developmental and disease-associated variation of splice variant and protein expression levels.	DST RBM5	2.55e-05	3	102	2	26784654
Pubmed	Clinicopathological significance of expression of Tspan-1, Jab1 and p27 in human hepatocellular carcinoma.	TSPAN1 COPS5	2.55e-05	3	102	2	20890423
Pubmed	Recently reported familial hypercholesterolemia-related mutations from cases in the Middle East and North Africa region.	ABCA1 APOB	2.55e-05	3	102	2	30694837
Pubmed	Fibroblast expression of α-smooth muscle actin, α2β1 integrin and αvβ3 integrin: influence of surface rigidity.	ITGA3 ITGAV	2.55e-05	3	102	2	21530503
Pubmed	Interaction domains of neurofilament light chain and brain spectrin.	SPTAN1 NEFL	2.55e-05	3	102	2	1902666
Pubmed	CCL2 increases αvβ3 integrin expression and subsequently promotes prostate cancer migration.	ITGAV CCL2	2.55e-05	3	102	2	23845726
Pubmed	Mass spectrometric based mapping of the disulfide bonding patterns of integrin alpha chains.	ITGA3 ITGAV	2.55e-05	3	102	2	14596610
Pubmed	Interaction of integrin alpha(v)beta3 with nectin. Implication in cross-talk between cell-matrix and cell-cell junctions.	ITGAV NECTIN1	2.55e-05	3	102	2	16679515
Pubmed	Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.	STAB2 ITGAV	2.55e-05	3	102	2	22566688
Pubmed	The COP9 signalosome controls ubiquitinylation of ABCA1.	ABCA1 COPS5	2.55e-05	3	102	2	19268428
Pubmed	Ankyrin-independent membrane protein-binding sites for brain and erythrocyte spectrin.	SPTA1 SPTAN1	2.55e-05	3	102	2	2971657
Pubmed	Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival.	ERAP1 NCF2	2.55e-05	3	102	2	33651148
Pubmed	Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B.	CHRM3 PLCE1	2.55e-05	3	102	2	11877431
Pubmed	Synchronous regulation of the determinants of endometrial receptivity to interleukin 1 at key stages of early embryo implantation in vivo.	CCL2 IL1RN	2.55e-05	3	102	2	24534280
Pubmed	Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex.	ITGA3 ITGAV	2.55e-05	3	102	2	10069334
Pubmed	Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.	ABCA1 NPC1L1	2.55e-05	3	102	2	15604518
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZHX3 SLC39A10 PDE4DIP GIGYF2 MACF1 USP33 ARAP2 PLCE1	2.76e-05	407	102	8	12693553
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SPTAN1 KIAA1671 DST NECTIN1 CGN GIGYF2 MACF1 CTNNA2 SNX2	4.44e-05	565	102	9	25468996
Pubmed	A novel function of apolipoprotein E: upregulation of ATP-binding cassette transporter A1 expression.	ABCA1 APOB	5.09e-05	4	102	2	21779326
Pubmed	M-cadherin distribution in the mouse adult neuromuscular system suggests a role in muscle innervation.	CHRNA1 NEFL	5.09e-05	4	102	2	8921257
Pubmed	Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex.	SPTA1 SPTAN1	5.09e-05	4	102	2	10551855
Pubmed	MCP-1 impacts RCT by repressing ABCA1, ABCG1, and SR-BI through PI3K/Akt posttranslational regulation in HepG2 cells.	ABCA1 CCL2	5.09e-05	4	102	2	23402987
Pubmed	Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.	ERAP1 USP33	5.09e-05	4	102	2	35192681
Pubmed	Mouse IL-1 receptor antagonist protein. Molecular characterization, gene mapping, and expression of mRNA in vitro and in vivo.	SPTAN1 IL1RN	5.09e-05	4	102	2	1828262
Pubmed	Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.	ITGA3 ITGAV	5.09e-05	4	102	2	16731529
Pubmed	Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.	SPTA1 SPTAN1	5.09e-05	4	102	2	12571280
Pubmed	Large-Scale Discovery and Validation Studies Demonstrate Significant Reductions in Circulating Levels of IL8, IL-1Ra, MCP-1, and MIP-1β in Patients With Type 1 Diabetes.	CCL2 IL1RN	5.09e-05	4	102	2	26158606
Pubmed	Endometrial receptivity: expression of alpha3beta1, alpha4beta1 and alphaVbeta1 endometrial integrins in women with impaired fertility.	ITGA3 ITGAV	5.09e-05	4	102	2	14666169
Pubmed	Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis.	CASK KIRREL1	5.09e-05	4	102	2	16874800
Pubmed	Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.	SPTA1 SPTAN1	5.09e-05	4	102	2	9593709
Pubmed	p53 modulation of TFIIH-associated nucleotide excision repair activity.	ERCC3 ERCC6	5.09e-05	4	102	2	7663514
Pubmed	In vivo phenotypic and molecular characterization of retinal degeneration in mouse models of three ciliopathies.	CEP290 BBS10	5.09e-05	4	102	2	31302159
Pubmed	The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.	SPTA1 SPTAN1	5.09e-05	4	102	2	21566095
Pubmed	Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.	SPTA1 SPTAN1	5.09e-05	4	102	2	3862089
Pubmed	Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sample.	ITGA3 ITGAV	5.09e-05	4	102	2	21182210
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	5.09e-05	4	102	2	8954775
Pubmed	Mapping of a spectrin-binding domain of human erythrocyte membrane protein 4.2.	SPTA1 SPTAN1	5.09e-05	4	102	2	12049649
Pubmed	Morphofunctional studies of the glomerular wall in mice lacking entactin-1.	ITGA3 ITGAV	5.09e-05	4	102	2	14566019
Pubmed	Disruption of spectrin-like cytoskeleton in differentiating keratinocytes by PKCδ activation is associated with phosphorylated adducin.	SPTA1 SPTAN1	5.09e-05	4	102	2	22163289
Pubmed	Characterization of the mouse JAB1 cDNA and protein.	DST COPS5	5.09e-05	4	102	2	10721695
Pubmed	The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins.	ITGA3 ITGAV	5.09e-05	4	102	2	15361064
Pubmed	Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.	SPTA1 SPTAN1	5.09e-05	4	102	2	12820899
Pubmed	The impact of APOA5, APOB, APOC3 and ABCA1 gene polymorphisms on ischemic stroke: Evidence from a meta-analysis.	ABCA1 APOB	5.09e-05	4	102	2	28865324
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	SPTAN1 ECPAS KIAA1671 DST CGN GIGYF2 KIRREL1 NIN	5.26e-05	446	102	8	24255178
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTA1 SPTAN1 SOS1	5.37e-05	25	102	3	8493579
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZHX3 ERAP1 DST GIGYF2 MACF1 NIN	5.50e-05	225	102	6	12168954
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	ABCA1 ERCC6 APOB MSH3 CCL2 IL1RN	6.07e-05	229	102	6	19948975
Pubmed	Functional proteomics mapping of a human signaling pathway.	ERCC6 CASK DST ZFYVE9 PDE4DIP MACF1 PLCG2 COPS5 SDK1	6.27e-05	591	102	9	15231748
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	ERCC6 CEP290 POMGNT1 BBS10 CCL2 MACF1	6.68e-05	233	102	6	32290105
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SPTAN1 MCM6 APOB MSH3 ECPAS NMD3 PIK3R4 TCERG1 RBM5 GIGYF2 EMC2 MED23 FKBP4 SNX2	7.21e-05	1425	102	14	30948266
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	ZHX3 ABCA1 APOB NPC1L1 MACF1	7.31e-05	146	102	5	20686565
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ERCC3 RIPK1 CEP290 SLC39A10 ECPAS SUN2 PDE4DIP GIGYF2 EMC2 NIN	7.66e-05	754	102	10	33060197
Pubmed	Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction.	CGN RAB13	8.47e-05	5	102	2	11025210
Pubmed	Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines.	PLCG2 SOS1	8.47e-05	5	102	2	10706702
Pubmed	A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.	ABCA1 NPC1L1	8.47e-05	5	102	2	18356535
Pubmed	The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons.	NEFL DST	8.47e-05	5	102	2	9971739
Pubmed	Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate.	SPTA1 PTPRO	8.47e-05	5	102	2	23533167
Pubmed	Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling.	ERAP1 CCL2	8.47e-05	5	102	2	16034137
Pubmed	Genome-wide association study of orthostatic hypotension and supine-standing blood pressure changes in two korean populations.	STAR CTNNA2	8.47e-05	5	102	2	24124408
Pubmed	Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.	SPTA1 SPTAN1	8.47e-05	5	102	2	3027087
Pubmed	Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.	DNAH2 DNAI7	8.47e-05	5	102	2	30060180
Pubmed	Spectrin interacts with EVL (Enabled/vasodilator-stimulated phosphoprotein-like protein), a protein involved in actin polymerization.	SPTA1 SPTAN1	8.47e-05	5	102	2	16336193
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SPTAN1 DST PDE4DIP MACF1 SOS1	8.57e-05	151	102	5	17043677
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RANBP3 SPTAN1 MSH3 DST CGN MACF1 SNX2	9.55e-05	360	102	7	33111431
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CCDC30 APOB SLC39A10 CASK KIAA1671 DST RBM5 KIRREL1 SDK1 ARAP2	9.80e-05	777	102	10	35844135
Pubmed	A protein interaction landscape of breast cancer.	ERAP1 MSH3 ECPAS KIAA1671 DST MACF1 CTNNA2 COPS5 FKBP4	1.07e-04	634	102	9	34591612
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	ERAP1 SPTAN1 APOB ITGA3 GALNT7 ITGAV NAA35 DST MACF1 HACL1 CTNNA2 FKBP4 RAB13	1.09e-04	1297	102	13	33545068
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ZHX3 ERCC6 PTPN22 ECPAS PIK3R4 GIGYF2 DNAI7 COPS5	1.11e-04	497	102	8	36774506
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RANBP3 SPTAN1 SLC39A10 NDUFS4 CASK NAA35 SUN2 KIRREL1 MACF1 EMC2 FKBP4 SNX2 USP33 NIN	1.13e-04	1487	102	14	33957083
Interaction	MAPRE1 interactions	ERCC6 SPTAN1 CEP290 MCM6 CASK PIK3R4 DST PDE4DIP GIGYF2 MACF1 COPS5 NIN	1.12e-05	514	102	12	int:MAPRE1
Interaction	RND2 interactions	SPTAN1 MCM6 SLC39A10 ITGAV CASK DST ZFYVE9 PTPRG SUN2 KIRREL1 EMC2	1.42e-05	440	102	11	int:RND2
Interaction	CYP2J2 interactions	ECPAS NDUFS4 SUN2 PDE4DIP	1.53e-05	30	102	4	int:CYP2J2
Interaction	HRAS interactions	SPTA1 SPTAN1 USP29 APOB ITGA3 SLC39A10 ECPAS NECTIN1 KIRREL1 FGD6 RAB13 ARAP2 PLCE1 SOS1	1.71e-05	725	102	14	int:HRAS
Interaction	GJA1 interactions	SPTAN1 APOB SLC39A10 CASK PIK3R4 DST ZFYVE9 PTPRG KIRREL1 MACF1 SDK1 ARAP2	3.87e-05	583	102	12	int:GJA1
Interaction	ARF6 interactions	SLC39A10 COG3 ECPAS CHRM3 CASK ZFYVE9 PTPRG PDE4DIP KIRREL1 FKBP4 SNX2 ARAP2	3.94e-05	584	102	12	int:ARF6
Interaction	OCLN interactions	SPTAN1 SLC39A10 CASK KIAA1671 DST ZFYVE9 PTPRG CGN KIRREL1 MACF1 ARAP2	4.58e-05	500	102	11	int:OCLN
Interaction	RHOU interactions	SPTAN1 MCM6 SLC39A10 ITGAV NMD3 CASK DST PTPRG KIRREL1 MACF1 EMC2	5.47e-05	510	102	11	int:RHOU
Interaction	DIRAS3 interactions	SPTAN1 SLC39A10 ECPAS DST PTPRG KIRREL1 MACF1 FKBP4	5.61e-05	262	102	8	int:DIRAS3
Interaction	RHOH interactions	SPTAN1 MCM6 SLC39A10 ITGAV CASK DST PTPRG SUN2 KIRREL1 EMC2 SNX2	5.67e-05	512	102	11	int:RHOH
Interaction	H2BC9 interactions	ABCA13 SPTAN1 CEP290 MCM6 MSH3 DST PDE4DIP RBM5 GIGYF2 FGD6	8.83e-05	446	102	10	int:H2BC9
Interaction	LAMP1 interactions	SPTAN1 ITGA3 SLC39A10 ITGAV CASK DST ZFYVE9 PTPRG KIRREL1 MACF1 EMC2 RAB13	1.00e-04	644	102	12	int:LAMP1
Interaction	SPTA1 interactions	ERCC3 ERCC6 SPTA1 PTPN22 PTPRO	1.16e-04	94	102	5	int:SPTA1
Interaction	ABI1 interactions	SPTA1 SPTAN1 ITGA3 DST TCERG1 SOS1 NIN	1.40e-04	223	102	7	int:ABI1
Interaction	FLOT1 interactions	ABCA1 SPTAN1 SLC39A10 ECPAS CASK DST ZFYVE9 KIRREL1 MACF1 NIN	1.48e-04	475	102	10	int:FLOT1
Interaction	RAB7A interactions	POMGNT1 SLC39A10 COG3 ITGAV PIK3R4 DST ZFYVE9 LRIG1 SUN2 EMC2 COPS5 RAB13 SNX2 USP33	1.48e-04	886	102	14	int:RAB7A
Interaction	RHOF interactions	SPTAN1 MSH3 SLC39A10 ECPAS ITGAV NMD3 CASK PTPRG SUN2 KIRREL1 MACF1 EMC2	1.51e-04	673	102	12	int:RHOF
Interaction	TMOD1 interactions	SPTAN1 ECPAS KIAA1671 MACF1 COPS5 NIN	1.69e-04	161	102	6	int:TMOD1
Interaction	C11orf52 interactions	SPTAN1 SLC39A10 CASK DST PTPRG KIRREL1 MACF1 ARAP2	1.84e-04	311	102	8	int:C11orf52
Interaction	PLTP interactions	FUT10 ABCA1 GALNT7 NMD3	1.86e-04	56	102	4	int:PLTP
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTAN1	4.00e-04	7	80	2	1113
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC3 ERCC6	4.00e-04	7	80	2	1268
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	5.32e-04	8	80	2	939
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA13	1.70e-03	14	80	2	805
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA3 ITGAV	2.83e-03	18	80	2	1160
GeneFamily	EF-hand domain containing	SPTA1 SPTAN1 DST MACF1 NIN	2.87e-03	219	80	5	863
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCG2 PLCE1	3.15e-03	19	80	2	832
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRG PTPRO	3.84e-03	21	80	2	813
GeneFamily	Bardet-Biedl syndrome associated\|BBSome	CEP290 BBS10	3.84e-03	21	80	2	980
GeneFamily	Ataxins\|Trinucleotide repeat containing	CASK GIGYF2	5.43e-03	25	80	2	775
GeneFamily	Fibronectin type III domain containing	IL31RA PTPRG PTPRO SDK1	5.55e-03	160	80	4	555
GeneFamily	Sterile alpha motif domain containing	SAMD9L BICC1 ARAP2	6.99e-03	88	80	3	760
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ZHX3 MSH3 CASK PIK3R4 DST ZFYVE9 LRIG1 GIGYF2 MACF1 AKAP10 DENND5A EMC2 SNX2 ARAP2 PLCE1 SOS1	2.00e-07	856	102	16	M4500
Coexpression	BAELDE_DIABETIC_NEPHROPATHY_DN	MCM6 ITGA3 ITGAV DST LRIG1 PTPRO PDE4DIP AKAP10 PLCG2 PLCE1	8.14e-06	437	102	10	M4665
Coexpression	GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN	CEP290 PTPN22 DHX33 ITGA3 CHRNA1 AKAP10 FGD6	1.36e-05	200	102	7	M4338
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	ABCA1 ITGA3 DST ZFYVE9 CGN ARAP2 PLCE1	1.55e-07	174	102	7	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|normal_Lymph_Node / Location, Cell class and cell subclass	NCF2 CLEC12A SLC6A12 CGN CCL2 CD302 IL1RN	2.03e-07	181	102	7	921e917f83105896ad8918dc134b871708024021
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA13 SPTA1 APOB GUCY2F SDK1 PLCE1	2.27e-07	184	102	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA13 SPTA1 APOB GUCY2F SDK1 PLCE1	2.27e-07	184	102	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA13 SPTA1 APOB GUCY2F SDK1 PLCE1	2.27e-07	184	102	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 ITGAV DST PTPRO PDE4DIP KIRREL1 PLCE1	2.53e-07	187	102	7	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERAP1 NCF2 CLEC12A SAMD9L PTPRO DENND5A IL1RN	2.72e-07	189	102	7	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHRM3 STAR PTPRG MACF1 PLCG2 FGD6 ARAP2	3.03e-07	192	102	7	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO CCL2 KIRREL1 LIX1 PLCE1	3.25e-07	194	102	7	43eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell	BAL-Mild-Myeloid-TRAM\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	8a31a459491aa8625802c5211d38d57c1e8be76b
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	4e518651ff219e163cfd9deb58566df6308aa3f7
ToppCell	Mild_COVID-19-Myeloid-TRAM3\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	4ab5da8ab757e8294c743949a5374b6e6a388913
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	af167e7a16c3537ce0aa821f608cdcb0c3abc07f
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	4b88ce864dc75ed8596a076ce4498f73639bbac8
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NCF2 CLEC12A DST PDE4DIP CD302 IL1RN RAB13	3.86e-07	199	102	7	bae7aa25f9e23fea19371390b8306e9dc3e4d549
ToppCell	mild-CD163+_Monocytes_(Sample_ID1_d7)\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA1 NCF2 CLEC12A SAMD9L CCL2 IL1RN FGD6	3.99e-07	200	102	7	82126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A SLC6A12 PTPRO CCL2 PLCG2	1.50e-06	154	102	6	27f76e4b3c055aa382708f1610c685f02d6d6114
ToppCell	facs-Lung-Endomucin-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A SLC6A12 PTPRO CCL2 PLCG2	1.50e-06	154	102	6	8746663a822d93a8510081c81a8c971b51653067
ToppCell	droplet-Fat-Scat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN SNX2	2.48e-06	168	102	6	749eccebe4ee066f827d2a3980512f195f23ac27
ToppCell	10x5'-Liver-Myeloid_Mac-Intermediate_macrophages\|Liver / Manually curated celltypes from each tissue	ABCA1 NCF2 CD302 DENND5A IL1RN RAB13	2.75e-06	171	102	6	25e0333743affdb662223fb5220b8a61fa02ad9f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 ABCA1 ABCA13 SAMD9L DNAI7 NIN	3.14e-06	175	102	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	NCF2 COG3 CHRNA1 DST CD302 DENND5A	3.25e-06	176	102	6	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IL31RA STAB2 CHRM3 CNTNAP5 DST PLCG2	3.69e-06	180	102	6	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGA3 DST ZFYVE9 CGN ARAP2 PLCE1	4.19e-06	184	102	6	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGA3 DST ZFYVE9 CGN ARAP2 PLCE1	4.19e-06	184	102	6	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO PDE4DIP KIRREL1 PLCE1	4.33e-06	185	102	6	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO PDE4DIP KIRREL1 PLCE1	4.33e-06	185	102	6	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO PDE4DIP KIRREL1 PLCE1	4.33e-06	185	102	6	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IL31RA STAB2 CHRM3 CNTNAP5 DST PLCG2	4.60e-06	187	102	6	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRG SDK1 LIX1 BICC1	4.89e-06	189	102	6	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	moderate-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IL31RA STAB2 CHRM3 CNTNAP5 DST PLCG2	4.89e-06	189	102	6	6011b747e27d61d222380a7bffdd921a68e9b657
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRG SDK1 LIX1 BICC1	4.89e-06	189	102	6	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 ITGAV PTPRO SUN2 KIRREL1 PLCE1	5.04e-06	190	102	6	92710caaff05123cf8e909319d7ac441d9b31a66
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	ABCA13 SPTA1 PTPN22 CNTNAP5 CTNNA2 ARAP2	5.04e-06	190	102	6	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA1 FSIP1 PTPRG CCL2 SDK1 BICC1	5.19e-06	191	102	6	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 ITGAV DST PTPRO KIRREL1 PLCE1	5.35e-06	192	102	6	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 ITGAV DST PTPRO KIRREL1 PLCE1	5.51e-06	193	102	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC30 ABCA13 DNAH2 CFAP65 LRIG1 SDK1	5.51e-06	193	102	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ABCA13 DNAH2 TSPAN1 CFAP65 CGN FBXO15	5.68e-06	194	102	6	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST PTPRG PDE4DIP KIRREL1 SDK1 BICC1	5.68e-06	194	102	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	IL31RA PTPN22 NCF2 CLEC12A PLCG2 IL1RN	5.68e-06	194	102	6	6b48383151b678489bcd6133d389a5d8b3a50186
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 FSIP1 ABCA13 DNAH2 PLCG2 DNAI7	5.68e-06	194	102	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST KIRREL1 SDK1 LIX1 BICC1	5.85e-06	195	102	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST KIRREL1 SDK1 LIX1 BICC1	5.85e-06	195	102	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	VE-granulo1-\|VE / Condition, Cell_class and T cell subcluster	NCF2 CLEC12A CCL2 CD302 IL1RN RAB13	6.02e-06	196	102	6	ab3f2ce294c7e503d86254a195be0cf500a2c5e4
ToppCell	VE-granulo1\|VE / Condition, Cell_class and T cell subcluster	NCF2 CLEC12A CCL2 CD302 IL1RN RAB13	6.02e-06	196	102	6	6dbd3acb30173d7f0b7bca0a82f435f00ca85835
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA1 DST CCL2 MACF1 CD302 DNAI7	6.20e-06	197	102	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 ITGA3 DST CGN ARAP2 PLCE1	6.20e-06	197	102	6	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 FSIP1 CEP290 DNAH2 CFAP65 DNAI7	6.20e-06	197	102	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	390C-Myeloid-Monocyte-CD16+_Monocyte\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABCA1 NCF2 PDE4DIP CCL2 DENND5A IL1RN	6.20e-06	197	102	6	01f5f5c34e904cc0146e978cc05ed1cd86a41533
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 NCF2 CLEC12A PTPRO CD302 RAB13	6.38e-06	198	102	6	579a22199643440b98e381147779ced630d4ed66
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 NCF2 CLEC12A CD302 IL1RN RAB13	6.57e-06	199	102	6	c4fc638a8dad3a9b77634e8912a9326c8a2f11f5
ToppCell	BAL-Mild-Myeloid-TRAM\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCF2 CLEC12A DST CD302 IL1RN RAB13	6.57e-06	199	102	6	27c63da6b29a1fc57ed2568443ba5029f3cdb186
ToppCell	Mild-Myeloid-Macrophages-FCN1+SPP1+\|Mild / Condition, Lineage, Cell class and cell subclass	NCF2 CLEC12A DST CD302 IL1RN RAB13	6.57e-06	199	102	6	2cbaef86af870a228cb46895dd765ea8894c83c5
ToppCell	distal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 DNAH2 TSPAN1 CFAP65 DNAI7 FBXO15	6.57e-06	199	102	6	7e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 NCF2 CLEC12A CD302 IL1RN RAB13	6.57e-06	199	102	6	697a9a58c0cdb77222700d029873355d37f6ab28
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 NCF2 CLEC12A CD302 IL1RN RAB13	6.57e-06	199	102	6	6783d571d28eac891fcc70380f176b53f35c88ba
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTAN1 DST PTPRG MACF1 FGD6 NIN	6.76e-06	200	102	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CCDC30 ABCA13 TSPAN1 CFAP65 DNAI7 PLCE1	6.76e-06	200	102	6	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC30 ABCA13 DNAH2 TSPAN1 CFAP65 DNAI7	6.76e-06	200	102	6	ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Ciliated\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CCDC30 ABCA13 DNAH2 TSPAN1 CFAP65 DNAI7	6.76e-06	200	102	6	a521cf837cadf280505ff9d7e641a205af7d6513
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC30 ABCA13 DNAH2 TSPAN1 CFAP65 DNAI7	6.76e-06	200	102	6	918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEP290 MCM6 STAR KIAA1671 EMC2	1.84e-05	141	102	5	b5e85f89b930a0ec70cc95733c5ab76ac3e9497f
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN	2.32e-05	148	102	5	bbf4933582b50b3412c805de5ed137107c996236
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN	2.32e-05	148	102	5	6543860e3207a7de92a35bb6004be51287582f7a
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN	2.32e-05	148	102	5	79e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCell	facs-Lung-Endomucin-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A SLC6A12 PTPRO IL1RN	2.64e-05	152	102	5	962f5bf632da79bd933193d3edd7d89941a85831
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|390C / Donor, Lineage, Cell class and subclass (all cells)	FSIP1 CHRNA1 SAMD9L NECTIN1 PARPBP	2.89e-05	155	102	5	afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELAPOR2 ABCA13 USP29 CNTNAP5 GUCY2F	3.58e-05	162	102	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCF2 CLEC12A PTPRO CD302 SNX2	3.79e-05	164	102	5	f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC30 SPTA1 LRIG1 EMC2 IL1RN	4.25e-05	168	102	5	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 ITGAV PTPRO KIRREL1 PLCE1	4.25e-05	168	102	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	FUT10 ECPAS ITGAV DENND5A EMC2	4.25e-05	168	102	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	droplet-Fat-Scat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN	4.25e-05	168	102	5	02dfe8037e61f9d4ac5f8df3929673bc212fd2cd
ToppCell	droplet-Fat-Scat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO CCL2 IL1RN	4.25e-05	168	102	5	94916feefd413c84bb7d3fd2d3e403036b705b69
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO KIRREL1 PLCE1	4.25e-05	168	102	5	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAV DST PTPRO KIRREL1 PLCE1	4.25e-05	168	102	5	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO PLCG2 IL1RN	4.37e-05	169	102	5	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO PLCG2 IL1RN	4.37e-05	169	102	5	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CLEC12A PTPRO PLCG2 IL1RN	4.37e-05	169	102	5	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTA1 CHRNA1 CNTNAP5 CTNNA2 LIX1	4.63e-05	171	102	5	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CCDC30 ABCA13 TSPAN1 CFAP65 DNAI7	4.76e-05	172	102	5	187ae91148d293537afc77e10da2b64302322224
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 DST PTPRO KIRREL1 PLCE1	4.76e-05	172	102	5	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL31RA ZFYVE9 TCERG1 GIGYF2 NIN	4.89e-05	173	102	5	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	NCF2 CLEC12A CD302 IL1RN RAB13	4.89e-05	173	102	5	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL31RA ZFYVE9 TCERG1 GIGYF2 NIN	4.89e-05	173	102	5	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZHX3 DST PTPRG KIRREL1 MACF1	5.16e-05	175	102	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	COVID-19-Myeloid-MoAM4\|COVID-19 / Condition, Lineage and Cell class	SLC39A10 CLEC12A NEFL DST PTPRO	5.45e-05	177	102	5	ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 STAB2 SLC39A10 DST PDE4DIP	5.45e-05	177	102	5	26bad614560609d318bfc9c235a698bca4e1c22c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 ABCA1 CEP290 DST PDE4DIP	5.60e-05	178	102	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 USP29 CLEC12A CCL2 DENND5A	5.60e-05	178	102	5	fbf49766e1504df554856b84c0576c06f3167329
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 PITPNM1 RMI1 DNAI7 PLCE1	5.75e-05	179	102	5	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 PITPNM1 RMI1 DNAI7 PLCE1	5.75e-05	179	102	5	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 SLC6A12 PTPRG LIX1 BICC1	6.06e-05	181	102	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SPTAN1 SLC39A10 LRIG1 MACF1 ARAP2	6.06e-05	181	102	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CCDC30 ABCA13 DNAH2 CFAP65 DNAI7	6.22e-05	182	102	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 SLC6A12 PTPRG LIX1 BICC1	6.22e-05	182	102	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IL31RA PTPN22 NCF2 CLEC12A IL1RN	6.38e-05	183	102	5	aed12b743334f3813db0c70d4fe7df90e0673f54
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	CCDC30 NCF2 PITPNM1 RMI1 DNAI7	6.38e-05	183	102	5	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA3 PTPRO PDE4DIP KIRREL1 PLCE1	6.38e-05	183	102	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
Drug	Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; HL60; HG-U133A	ZHX3 ABCA1 ERAP1 NMD3 ZFYVE9 MACF1 IL1RN SOS1	3.21e-06	199	102	8	1436_UP
Drug	Harzol	ABCA1 APOB STAR NPC1L1 CCL2	9.35e-06	63	102	5	CID000006744
Drug	Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; HL60; HT_HG-U133A	ZHX3 ABCA1 SPTAN1 PTPN22 ITGAV PDE4DIP IL1RN	9.58e-06	165	102	7	2136_UP
Disease	cerebrospinal fluid clusterin measurement	ABCA13 DST CTNNA2 IPMK	6.00e-06	35	100	4	EFO_0007657
Disease	fibromyalgia (is_marker_for)	CCL2 IL1RN	3.40e-05	3	100	2	DOID:631 (is_marker_for)
Disease	nephrotic syndrome (is_implicated_in)	IL1RN PLCE1	1.13e-04	5	100	2	DOID:1184 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_implicated_in)	ERCC3 ERCC6 MSH3 IL1RN SDHC	1.13e-04	139	100	5	DOID:3908 (is_implicated_in)
Disease	Lissencephaly	MACF1 CTNNA2	1.69e-04	6	100	2	C0266463
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC3 ERCC6	1.69e-04	6	100	2	DOID:2962 (implicated_via_orthology)
Disease	familial hyperlipidemia (is_implicated_in)	APOB CCL2	3.14e-04	8	100	2	DOID:1168 (is_implicated_in)
Disease	Henoch-Schoenlein purpura (is_implicated_in)	CCL2 IL1RN	3.14e-04	8	100	2	DOID:11123 (is_implicated_in)
Disease	anterior uveitis (is_implicated_in)	CCL2 IL1RN	3.14e-04	8	100	2	DOID:1407 (is_implicated_in)
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma	CNTNAP5 CTNNA2 ARAP2	3.16e-04	39	100	3	EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Disease	pulmonary tuberculosis (is_implicated_in)	PTPN22 CCL2 IL1RN	3.94e-04	42	100	3	DOID:2957 (is_implicated_in)
Disease	alopecia areata (is_implicated_in)	PTPN22 IL1RN	4.03e-04	9	100	2	DOID:986 (is_implicated_in)
Disease	linoleic acid measurement	ZHX3 ZNF311 ABCA1 APOB BICC1	4.38e-04	186	100	5	EFO_0006807
Disease	cardiovascular system disease (is_marker_for)	APOB CCL2	5.03e-04	10	100	2	DOID:1287 (is_marker_for)
Disease	cystic kidney disease (implicated_via_orthology)	CEP290 BICC1	5.03e-04	10	100	2	DOID:2975 (implicated_via_orthology)
Disease	Graves ophthalmopathy (is_implicated_in)	PTPN22 IL1RN	5.03e-04	10	100	2	DOID:0081120 (is_implicated_in)
Disease	response to carboplatin, response to antineoplastic agent	LRIG1 PLCG2	5.03e-04	10	100	2	GO_0097327, GO_0097328
Disease	omega-6 polyunsaturated fatty acid measurement	ZHX3 ZNF311 ABCA1 APOB RMI1	5.68e-04	197	100	5	EFO_0005680
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	6.13e-04	11	100	2	DOID:3717 (is_implicated_in)
Disease	antihyperlipidemic drug use measurement	ABCA1 MCM6 APOB NPC1L1	6.44e-04	115	100	4	EFO_0803367
Disease	Leigh disease (implicated_via_orthology)	NDUFS4 SDHC	7.34e-04	12	100	2	DOID:3652 (implicated_via_orthology)
Disease	Bronchial Hyperreactivity	CCL2 IL1RN	7.34e-04	12	100	2	C0085129
Disease	anxiety disorder, stress-related disorder	GIGYF2 SDK1	7.34e-04	12	100	2	EFO_0006788, EFO_0010098
Disease	hyperglycemia (is_marker_for)	ITGAV IL1RN	8.66e-04	13	100	2	DOID:4195 (is_marker_for)
Disease	Graves ophthalmopathy (is_marker_for)	CCL2 IL1RN	8.66e-04	13	100	2	DOID:0081120 (is_marker_for)
Disease	Myasthenia gravis	PTPN22 CHRNA1	8.66e-04	13	100	2	EFO_0004991
Disease	Bardet-Biedl Syndrome	CEP290 BBS10	8.66e-04	13	100	2	C0752166
Disease	Hyperlipoproteinemia Type IIb	ABCA1 APOB	8.66e-04	13	100	2	C1704417
Disease	docosahexaenoic acid measurement	ABCA1 APOB CTNNA2 IPMK	9.33e-04	127	100	4	EFO_0007761
Disease	anti-basement membrane glomerulonephritis (implicated_via_orthology)	CCL2 IL1RN	1.01e-03	14	100	2	DOID:4780 (implicated_via_orthology)
Disease	rheumatoid arthritis (is_implicated_in)	PTPN22 NCF2 IL1RN	1.02e-03	58	100	3	DOID:7148 (is_implicated_in)
Disease	Endometrial Neoplasms	MSH3 STAR CCL2	1.02e-03	58	100	3	C0014170
Disease	autoimmune thrombocytopenic purpura (is_implicated_in)	PTPN22 IL1RN	1.16e-03	15	100	2	DOID:8924 (is_implicated_in)
Disease	systemic lupus erythematosus (is_implicated_in)	PTPN22 CCL2 IL1RN	1.24e-03	62	100	3	DOID:9074 (is_implicated_in)
Disease	ceramide measurement	ABCA1 APOB NMD3 PLCG2 SDK1	1.25e-03	235	100	5	EFO_0010222
Disease	Hyperlipoproteinemia Type IIa	ABCA1 APOB	1.32e-03	16	100	2	C0745103
Disease	temporal arteritis (is_implicated_in)	PTPN22 CCL2	1.32e-03	16	100	2	DOID:13375 (is_implicated_in)
Disease	pulmonary fibrosis (is_implicated_in)	CHRM3 IL1RN	1.32e-03	16	100	2	DOID:3770 (is_implicated_in)
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ABCA1 APOB NPC1L1 MACF1	1.48e-03	144	100	4	EFO_0004611, EFO_0020943
Disease	Bardet-Biedl syndrome 1 (disorder)	CEP290 BBS10	1.50e-03	17	100	2	C2936862
Disease	lupus nephritis (is_marker_for)	CCL2 IL1RN	1.50e-03	17	100	2	DOID:0080162 (is_marker_for)
Disease	graft-versus-host disease (is_implicated_in)	PTPN22 IL1RN	1.50e-03	17	100	2	DOID:0081267 (is_implicated_in)
Disease	stem Cell Factor measurement	FUT10 ABCA1 PLCG2	1.55e-03	67	100	3	EFO_0008291
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	ABCA1 APOB MACF1	1.55e-03	67	100	3	EFO_0008595, EFO_0020946
Disease	late-onset myasthenia gravis	PTPN22 CHRNA1	1.68e-03	18	100	2	EFO_1001490
Disease	Bardet-Biedl syndrome	CEP290 BBS10	1.68e-03	18	100	2	cv:C0752166
Disease	Hypercholesterolemia, Familial	ABCA1 APOB	1.68e-03	18	100	2	C0020445
Disease	Sjogren's syndrome (is_implicated_in)	PTPN22 IL1RN	1.68e-03	18	100	2	DOID:12894 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ABCA1 APOB GOLPH3L NPC1L1	1.85e-03	153	100	4	EFO_0004611, EFO_0020944
Disease	cerebral infarction (is_marker_for)	APOB SOS1	1.87e-03	19	100	2	DOID:3526 (is_marker_for)
Disease	Endometrial Carcinoma	MSH3 STAR CCL2	1.90e-03	72	100	3	C0476089
Disease	type 1 diabetes mellitus (is_marker_for)	APOB CCL2 IL1RN	1.90e-03	72	100	3	DOID:9744 (is_marker_for)
Disease	coronary artery disease	ZHX3 ABCA1 CCDC30 APOB PTPRO GIGYF2 PLCG2 DENND5A FGD6 BICC1 PLCE1	2.40e-03	1194	100	11	EFO_0001645
Disease	colorectal carcinoma (is_implicated_in)	ERCC6 MSH3	2.51e-03	22	100	2	DOID:0080199 (is_implicated_in)
Disease	progression free survival, ovarian serous carcinoma	ABCA13 CTNNA2	2.51e-03	22	100	2	EFO_0004920, EFO_1001516
Disease	Rheumatoid Arthritis	PTPN22 NCF2 CLEC12A IL1RN	2.95e-03	174	100	4	C0003873
Disease	Sjogren's syndrome (is_marker_for)	NEFL IL1RN	2.99e-03	24	100	2	DOID:12894 (is_marker_for)
Disease	Behcet Syndrome	ERAP1 APOB	2.99e-03	24	100	2	C0004943
Disease	interstitial lung disease (is_marker_for)	CCL2 IL1RN	3.24e-03	25	100	2	DOID:3082 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GFDNESSNKTWMKNT	PTPRG	106	P23470
KTWELANNMQEAQSI	COPS5	11	Q92905
SQAMKKWVQGNTDEA	AKAP10	616	O43572
DNSNMTFDKWTDQDD	CD302	106	Q8IX05
MTGLDTKNNVKVWFN	ABCA1	1581	O95477
TTKSWKPSSEQMDQD	CHRM3	316	P20309
KKDNWNVSNVLMTFT	ABCA13	2751	Q86UQ4
QMDIENSFITKWKDT	ARAP2	1306	Q8WZ64
FFQKIMEETNTQIAW	BICC1	76	Q9H694
AQFQTSQFWIMEKTK	BBS10	281	Q8TAM1
SQAQTEAFWENKQME	ERCC6	1161	Q03468
NTKLWAQMQIDKASE	RANBP3	456	Q9H6Z4
TDEKSFENIQNWMKS	RAB13	91	P51153
FENIQNWMKSIKENA	RAB13	96	P51153
SFDKNADTTMKWQTK	PTPN22	386	Q9Y2R2
KDDYMISKDNWNNVN	PARPBP	436	Q9NWS1
TDTWKEMLKFQDATA	HACL1	491	Q9UJ83
MKSDQESNNAAAEWK	CHRNA1	406	P02708
KWTEEFNMEETQTSL	MSH3	1121	P20585
AMEKTKQEQQASCTW	CASK	686	O14936
VKEWEKVFEMSQDKN	MCM6	331	Q14566
KGNSATEEEIWKFMN	MAGEB1	211	P43366
TDNTWMFKDSTEEKS	KIAA1671	1681	Q9BY89
MTFAWKKDNEVLTNA	LRIG1	526	Q96JA1
SEDSMKDAWGQVKNY	NCF2	406	P19878
NSTSWMEVNFAKNRK	IL31RA	166	Q8NI17
DKDMVQSKLDFSQVW	DST	5576	Q03001
WNEQSTKFMDQKNSL	CFAP65	1711	Q6ZU64
FVDKTEWIKSLMNNS	ECPAS	691	Q5VYK3
KNTKNEDLWDSMASI	ERAP1	471	Q9NZ08
NMENKTTWFSVDIDS	ITGA3	966	P26006
KWKSMSNENDIITHF	MED23	766	Q9ULK4
DTKENNMKYWEKNQS	PLCG2	911	P16885
QDATSWMEANQKKLV	RBM5	151	P52756
NDQCQEMDTTTDKWV	ELAPOR2	221	A8MWY0
KVENLEQDNGWKSMS	IPMK	336	Q8NFU5
VSMLQEFWESKQQQK	LIX1	31	Q8N485
SIDEMNNAWENLNKT	MACF1	6086	Q9UPN3
ETRNDFWKMVLQQKS	PTPRO	1016	Q16827
NQTLMGQTSQVDWKD	NPC1L1	506	Q9UHC9
FEWNTGTNVDTKKMT	APOB	1176	P04114
KVAQDNMDVFKDQWE	CTNNA2	476	P26232
TKNSNMGFWDDAVKE	GIGYF2	1071	Q6Y7W6
QAWEQETKLGNESSM	CEP290	1026	O15078
KWVQDSMDHLDKQTQ	CCL2	81	P13500
RSNWKFNSVEKIAMS	FBXO15	126	Q8NCQ5
WFAKLQTQMDQDEGT	COG3	111	Q96JB2
EMWISSFEQSKKEAQ	FUT10	441	Q6P4F1
DSSKTTQKWEMNNIH	GALNT7	641	Q86SF2
TNQDVKLDWMFKSSL	GUCY2F	636	P51841
SLLWTETFMNKENQN	ITGAV	931	P06756
GTTAKEEMERFWNKN	SDHC	31	Q99643
NSEKKMESEEDSNWE	GOLPH3L	16	Q9H4A5
MSQEKNEMFESEWSK	CCDC30	1	Q5VVM6
QEMNTFISLWKEKTN	DNAI7	111	Q6TDU7
KDWCKENFVNSKNMT	DHX33	576	Q9H6R0
NKTWKEMRATQEDFD	ELMO3	451	Q96BJ8
DKESWFTNREQMQNF	DENND5A	541	Q6IQ26
EAWQSKEEMENTKKF	FSIP1	161	Q8NA03
WTKKDSNMVLSNSNQ	KIRREL1	341	Q96J84
KSSKMQAFRIWDVNQ	IL1RN	31	P18510
KDNMKYASWAASQIN	EMC2	251	Q15006
NSAVSVEQWKAQFKM	ERCC3	366	P19447
SFEKAKESWEMNSEE	FKBP4	251	Q02790
TLFDQVNSNWKAIMD	DNAH2	1471	Q9P225
YWEADSQNETEKMKV	SDK1	1741	Q7Z5N4
GKQKWFMKQNTEEST	SLC39A10	526	Q9ULF5
VNNTKKWKMEFDTRE	NDUFS4	91	O43181
KQEDSIWTFAGNMNA	CNTNAP5	121	Q8WYK1
TKNDTVWDLNMYKSE	TAS2R10	156	Q9NYW0
TIKMNESDAWFEEKQ	SNX2	296	O60749
ATMKQEQKSWEHQSA	NIN	1741	Q8N4C6
VSDENSNEKCWEKIM	PLCE1	81	Q9P212
NNWSEKNVSEQMTNE	RMI1	371	Q9H9A7
NQYEDKTTNMWEKIS	SAMD9L	471	Q8IVG5
MEKDDDFTTWTQLAK	POMGNT1	581	Q8WZA1
DQVKDRGQWTNKMEF	SLC6A12	31	P48065
SFKMWSKLNNEEHNE	RIPK1	161	Q13546
FSAKSAEEKNNWMAA	SOS1	526	Q07889
WQSMFQKNKEDLRAT	CGN	571	Q9P2M7
FLSDDVQTWQESKMA	CLEC12A	146	Q5QGZ9
QDSNVNEEWKSMFGS	PIK3R4	851	Q99570
KEMTKWNSNDFIDAF	PITPNM1	366	O00562
KMEKSNTNWVDITQD	NAA35	21	Q5VZE5
LKSEWQSMTQESFQE	SUN2	391	Q9UH99
SIQKWQFSMSAIKEE	TCERG1	596	O14776
WKKESQQDNGDKVMS	STAR	96	P49675
TEQVDNWMSKQEAFL	SPTAN1	476	Q13813
KFWSQEKNMLVQESQ	SOGA1	651	O94964
KTQELEWQNSSSMED	FGD6	771	Q6ZV73
KSQQPMKSDDDWSVF	USP29	106	Q9HBJ7
DMDQDEKSFWLSQSN	STAB2	1041	Q8WWQ8
KASALNNWCEKMEEN	SPTA1	2051	P02549
MQQVKRWSDIQKDSF	UGT2B28	91	Q9BY64
KTQMSSQQVKQWFAE	ZHX3	871	Q9H4I2
SQQVKQWFAEKMGEE	ZHX3	876	Q9H4I2
NWKLTKLNEMNDSQV	ZFYVE9	401	O95405
QDDENNSEMSKDWQK	USP33	351	Q8TEY7
ADKMWPENEKASSQQ	ZNF311	141	Q5JNZ3
GSQEDFTQVWNTTMK	TSPAN1	131	O60635
DRNSTWKADMNDKFT	PP2D1	176	A8MPX8
WKADMNDKFTVVSNF	PP2D1	181	A8MPX8
QNLQWLKEEMETKFS	PDE4DIP	556	Q5VU43
WVQKTSEMNTDKQYF	NMD3	346	Q96D46
KNMQNAEEWFKSRFT	NEFL	271	P07196
MVSQNDGSFISKKEW	NECTIN1	501	Q15223