Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	HGFAC PRSS1 PRSS2 KLK6 RHBDL1 HTRA3 CELA2B F2 PRSS3P2 LPA TMPRSS3 TMPRSS11D KLKB1	1.42e-08	190	176	13	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	HGFAC PRSS1 PRSS2 KLK6 RHBDL1 HTRA3 CELA2B F2 PRSS3P2 LPA TMPRSS3 TMPRSS11D KLKB1	3.95e-08	207	176	13	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	HGFAC PRSS1 PRSS2 KLK6 RHBDL1 HTRA3 CELA2B F2 PRSS3P2 LPA TMPRSS3 TMPRSS11D KLKB1	5.23e-08	212	176	13	GO:0017171
GeneOntologyMolecularFunction	endopeptidase activity	HGFAC PRSS1 PRSS2 KLK6 ADAM21 RHBDL1 HTRA3 CELA2B F2 PIK3IP1 PRSS3P2 USP6 CNTNAP5 LPA TMPRSS3 TMPRSS11D KLKB1	2.77e-07	430	176	17	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	HGFAC PRSS1 PRSS2 KLK6 ADAM21 RHBDL1 HTRA3 CELA2B F2 PIK3IP1 PRSS3P2 METAP1 USP6 CNTNAP5 LPA TMPRSS3 TMPRSS11D USPL1 KLKB1	5.43e-06	654	176	19	GO:0008233
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL3A1 COL6A3 LAMA3 COLQ SRPX2 HMCN2 NID1 COL14A1 MUC5AC PCOLCE	6.76e-06	188	176	10	GO:0005201
GeneOntologyMolecularFunction	UDP phosphatase activity	ENTPD7 ENTPD4 ENTPD2	5.44e-05	9	176	3	GO:0045134
GeneOntologyMolecularFunction	structural molecule activity	COL3A1 COL6A3 OBSCN LAMA3 EVPL FLG2 COLQ CRYBA2 JUP SRPX2 HMCN2 LORICRIN MACF1 NID1 COL14A1 TLN2 BSN MUC5AC PCOLCE MYBPC3	1.20e-04	891	176	20	GO:0005198
GeneOntologyMolecularFunction	GDP phosphatase activity	ENTPD7 ENTPD4 ENTPD2	1.40e-04	12	176	3	GO:0004382
GeneOntologyMolecularFunction	nucleoside diphosphate phosphatase activity	ENTPD7 ENTPD4 ENTPD2	6.87e-04	20	176	3	GO:0017110
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL3A1 COL6A3 COLQ COL14A1	7.13e-04	46	176	4	GO:0030020
GeneOntologyMolecularFunction	collagen binding	ITGA11 ITGA10 NID1 COL14A1 PCOLCE	7.50e-04	81	176	5	GO:0005518
GeneOntologyMolecularFunction	collagen binding involved in cell-matrix adhesion	ITGA11 ITGA10	7.59e-04	5	176	2	GO:0098639
GeneOntologyMolecularFunction	cell adhesion molecule binding	COL3A1 FLNB ITGA11 OBSCN ITGA10 EVPL NLGN1 JAML GFRA1 JUP TENM3 CNTN5 MACF1 TLN2	8.83e-04	599	176	14	GO:0050839
GeneOntologyMolecularFunction	calcium ion binding	PRSS1 PRSS2 STAB2 REG4 ENPP3 CUBN FLG2 F2 USP6 FAT2 HMCN2 CELSR2 RPTN MACF1 NID1 PCDH8	9.94e-04	749	176	16	GO:0005509
GeneOntologyMolecularFunction	MAP kinase kinase kinase kinase activity	MAP4K3 MAP4K2	1.13e-03	6	176	2	GO:0008349
GeneOntologyMolecularFunction	CTPase activity	ENTPD7 ENTPD4	1.13e-03	6	176	2	GO:0043273
GeneOntologyBiologicalProcess	cell-cell adhesion	BOC IL12B ITGA11 ITGA10 LAMA3 NLGN1 JAML IGDCC4 METAP1 JUP FAT2 SRPX2 LRFN4 KLHL25 HMCN2 CELSR2 TENM3 CNTN5 PKHD1 COL14A1 TLN2 SIGLEC1 ATP1B2 PCDH8 MEGF11	3.75e-06	1077	173	25	GO:0098609
GeneOntologyCellularComponent	external side of plasma membrane	FCRL2 IL12B ITGA11 STAB2 ADAM21 ENPP3 ITGA10 PRND NLGN1 CUBN F2 CR2 GFRA1 FCRL3 LPA PKHD1 FCRL5 OSMR ATP1B2	8.68e-08	519	176	19	GO:0009897
GeneOntologyCellularComponent	cell surface	BOC FCRL2 IL12B ITGA11 STAB2 ADAM21 ENPP3 ITGA10 PRND NLGN1 CUBN F2 CR2 GFRA1 SRPX2 LRFN4 FCRL3 IGF2R LPA ENTPD2 TMPRSS11D TREM2 PKHD1 FCRL5 OSMR BSN ATP1B2 HSPA2	1.91e-07	1111	176	28	GO:0009986
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL3A1 PRSS1 COL6A3 PRSS2 WNT8A LAMA3 CELA2B F2 COLQ ITIH5 SRPX2 HMCN2 LPA ENTPD2 NID1 COL14A1 KAZALD1 PCOLCE	5.79e-07	530	176	18	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	COL3A1 PRSS1 COL6A3 PRSS2 WNT8A LAMA3 CELA2B F2 COLQ ITIH5 SRPX2 FCGBP HMCN2 LPA ENTPD2 NID1 COL14A1 KAZALD1 MUC5AC PCOLCE	7.22e-07	656	176	20	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL3A1 PRSS1 COL6A3 PRSS2 WNT8A LAMA3 CELA2B F2 COLQ ITIH5 SRPX2 FCGBP HMCN2 LPA ENTPD2 NID1 COL14A1 KAZALD1 MUC5AC PCOLCE	7.57e-07	658	176	20	GO:0030312
GeneOntologyCellularComponent	side of membrane	FCRL2 IL12B ITGA11 STAB2 ADAM21 ENPP3 ITGA10 PRND NLGN1 CUBN F2 CR2 GFRA1 JUP FCRL3 LORICRIN LPA CNTN5 PKHD1 FCRL5 OSMR ATP1B2	4.66e-06	875	176	22	GO:0098552
GeneOntologyCellularComponent	cornified envelope	KLK6 EVPL FLG2 JUP LORICRIN RPTN	2.53e-05	69	176	6	GO:0001533
GeneOntologyCellularComponent	intercalated disc	AKAP6 OBSCN OBSL1 JUP TLN2	2.71e-04	68	176	5	GO:0014704
GeneOntologyCellularComponent	striated muscle myosin thick filament	OBSCN MYBPC3	4.18e-04	4	176	2	GO:0005863
GeneOntologyCellularComponent	keratohyalin granule	CELA2B FLG2	6.93e-04	5	176	2	GO:0036457
GeneOntologyCellularComponent	cell-cell contact zone	AKAP6 OBSCN OBSL1 JUP TLN2	1.20e-03	94	176	5	GO:0044291
Domain	IGc2	BOC FCRL2 IL12B KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 FCRL3 HMCN2 PXDNL CNTN5 KAZALD1 SIGLEC1 FCRL5 MYBPC3	6.19e-11	235	172	17	SM00408
Domain	Ig_sub2	BOC FCRL2 IL12B KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 FCRL3 HMCN2 PXDNL CNTN5 KAZALD1 SIGLEC1 FCRL5 MYBPC3	6.19e-11	235	172	17	IPR003598
Domain	Ig-like_fold	IGSF8 BOC FCRL2 IL12B FLNB COL6A3 KALRN SPEG OBSCN OBSL1 JAML IGDCC4 FAM187B LRFN4 FCRL3 HMCN2 NFATC3 PXDNL CNTN5 TREM2 PKHD1 COL14A1 KAZALD1 SIGLEC1 FCRL5 OSMR MYBPC3	3.30e-10	706	172	27	IPR013783
Domain	-	IGSF8 BOC FCRL2 IL12B FLNB COL6A3 KALRN SPEG OBSCN OBSL1 JAML IGDCC4 FAM187B LRFN4 FCRL3 NFATC3 PXDNL CNTN5 TREM2 PKHD1 COL14A1 KAZALD1 SIGLEC1 FCRL5 OSMR MYBPC3	4.27e-10	663	172	26	2.60.40.10
Domain	Ig_I-set	BOC FCRL2 KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 HMCN2 PXDNL CNTN5 KAZALD1 SIGLEC1 MYBPC3	2.55e-09	190	172	14	IPR013098
Domain	I-set	BOC FCRL2 KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 HMCN2 PXDNL CNTN5 KAZALD1 SIGLEC1 MYBPC3	2.55e-09	190	172	14	PF07679
Domain	Ig-like_dom	IGSF8 BOC FCRL2 IL12B KALRN SPEG OBSCN OBSL1 JAML IGDCC4 FAM187B LRFN4 FCRL3 HMCN2 PXDNL CNTN5 TREM2 KAZALD1 SIGLEC1 FCRL5 MYBPC3	8.04e-09	503	172	21	IPR007110
Domain	IG	IGSF8 BOC FCRL2 KALRN SPEG OBSCN OBSL1 JAML IGDCC4 LRFN4 FCRL3 HMCN2 PXDNL CNTN5 TREM2 KAZALD1 SIGLEC1 FCRL5 MYBPC3	1.26e-08	421	172	19	SM00409
Domain	Ig_sub	IGSF8 BOC FCRL2 KALRN SPEG OBSCN OBSL1 JAML IGDCC4 LRFN4 FCRL3 HMCN2 PXDNL CNTN5 TREM2 KAZALD1 SIGLEC1 FCRL5 MYBPC3	1.26e-08	421	172	19	IPR003599
Domain	Trypsin_dom	HGFAC PRSS1 PRSS2 KLK6 HTRA3 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	1.56e-08	121	172	11	IPR001254
Domain	Trypsin	HGFAC PRSS1 PRSS2 KLK6 HTRA3 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	1.56e-08	121	172	11	PF00089
Domain	Peptidase_S1_PA	HGFAC PRSS1 PRSS2 KLK6 HTRA3 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	1.85e-08	123	172	11	IPR009003
Domain	IG_LIKE	IGSF8 BOC FCRL2 IL12B KALRN SPEG OBSCN OBSL1 JAML IGDCC4 LRFN4 FCRL3 HMCN2 PXDNL CNTN5 TREM2 KAZALD1 SIGLEC1 FCRL5 MYBPC3	2.82e-08	491	172	20	PS50835
Domain	fn3	BOC IL12B KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 CNTN5 COL14A1 OSMR MYBPC3	3.44e-08	162	172	12	PF00041
Domain	TRYPSIN_HIS	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	3.81e-08	103	172	10	IPR018114
Domain	FN3	BOC IL12B COL6A3 KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 CNTN5 COL14A1 OSMR MYBPC3	4.07e-08	199	172	13	PS50853
Domain	TRYPSIN_SER	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	5.02e-08	106	172	10	PS00135
Domain	TRYPSIN_HIS	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	5.49e-08	107	172	10	PS00134
Domain	FN3_dom	BOC IL12B COL6A3 KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 CNTN5 COL14A1 OSMR MYBPC3	7.25e-08	209	172	13	IPR003961
Domain	Peptidase_S1A	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	9.26e-08	113	172	10	IPR001314
Domain	TRYPSIN_DOM	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	1.09e-07	115	172	10	PS50240
Domain	Tryp_SPc	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 LPA TMPRSS3 TMPRSS11D KLKB1	1.29e-07	117	172	10	SM00020
Domain	TRYPSIN_SER	HGFAC PRSS1 PRSS2 KLK6 CELA2B F2 TMPRSS3 TMPRSS11D KLKB1	1.44e-07	90	172	9	IPR033116
Domain	FN3	BOC COL6A3 KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 CNTN5 COL14A1 OSMR MYBPC3	1.49e-07	185	172	12	SM00060
Domain	EGF-like_dom	HGFAC STAB2 ADAM21 LAMA3 CUBN FAT2 CNTNAP5 FCGBP HMCN2 CELSR2 TENM3 NID1 MEGF11	5.47e-07	249	172	13	IPR000742
Domain	EGF_1	HGFAC STAB2 ADAM21 LAMA3 CUBN FAT2 CNTNAP5 HMCN2 CELSR2 TENM3 NID1 MEGF11	4.44e-06	255	172	12	PS00022
Domain	EGF_2	HGFAC STAB2 ADAM21 LAMA3 CUBN FAT2 CNTNAP5 HMCN2 CELSR2 TENM3 NID1 MEGF11	6.58e-06	265	172	12	PS01186
Domain	Kringle-like	HGFAC F2 PIK3IP1 IGF2R LPA	1.03e-05	32	172	5	IPR013806
Domain	EGF	HGFAC STAB2 LAMA3 CUBN FAT2 CNTNAP5 FCGBP CELSR2 TENM3 NID1 MEGF11	1.18e-05	235	172	11	SM00181
Domain	EGF_3	HGFAC STAB2 ADAM21 CUBN FAT2 CNTNAP5 HMCN2 CELSR2 TENM3 NID1 MEGF11	1.18e-05	235	172	11	PS50026
Domain	Kringle_CS	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	IPR018056
Domain	KRINGLE_1	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	PS00021
Domain	KR	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	SM00130
Domain	Kringle	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	IPR000001
Domain	KRINGLE_2	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	PS50070
Domain	Kringle	HGFAC F2 PIK3IP1 LPA	1.51e-05	17	172	4	PF00051
Domain	VWC	COL3A1 KCP FCGBP PXDNL MUC5AC	2.45e-05	38	172	5	SM00214
Domain	EGF-like_CS	HGFAC STAB2 ADAM21 LAMA3 CUBN FAT2 HMCN2 CELSR2 TENM3 NID1 MEGF11	3.12e-05	261	172	11	IPR013032
Domain	VWF_dom	COL3A1 KCP FCGBP PXDNL MUC5AC	4.03e-05	42	172	5	IPR001007
Domain	GDA1_CD39_NTPase	ENTPD7 ENTPD4 ENTPD2	4.15e-05	8	172	3	IPR000407
Domain	GDA1_CD39	ENTPD7 ENTPD4 ENTPD2	4.15e-05	8	172	3	PF01150
Domain	GDA1_CD39_NTPASE	ENTPD7 ENTPD4 ENTPD2	4.15e-05	8	172	3	PS01238
Domain	Growth_fac_rcpt_	STAB2 LAMA3 HTRA3 CUBN HMCN2 CELSR2 NID1 KAZALD1	1.00e-04	156	172	8	IPR009030
Domain	VWFA	COL6A3 ITGA11 ITGA10 ITIH5 HMCN2 COL14A1	1.10e-04	82	172	6	PS50234
Domain	VWC	COL3A1 KCP PXDNL MUC5AC	1.20e-04	28	172	4	PF00093
Domain	VWA	COL6A3 ITGA11 ITGA10 ITIH5 HMCN2 COL14A1	1.25e-04	84	172	6	SM00327
Domain	EGF_dom	STAB2 CUBN NID1	1.59e-04	12	172	3	IPR024731
Domain	EGF_3	STAB2 CUBN NID1	1.59e-04	12	172	3	PF12947
Domain	VWA	COL6A3 ITGA11 ITGA10 ITIH5 COL14A1	1.63e-04	56	172	5	PF00092
Domain	Laminin_G	LAMA3 FAT2 CNTNAP5 CELSR2 COL14A1	1.93e-04	58	172	5	IPR001791
Domain	SPEC	AKAP6 KALRN EVPL MACF1	2.04e-04	32	172	4	SM00150
Domain	Spectrin/alpha-actinin	AKAP6 KALRN EVPL MACF1	2.04e-04	32	172	4	IPR018159
Domain	Unchr_dom_Cys-rich	KCP FCGBP MUC5AC	2.05e-04	13	172	3	IPR014853
Domain	C8	KCP FCGBP MUC5AC	2.05e-04	13	172	3	SM00832
Domain	TIL_dom	KCP FCGBP MUC5AC	2.59e-04	14	172	3	IPR002919
Domain	EGF_Lam	STAB2 LAMA3 CELSR2 MEGF11	2.91e-04	35	172	4	SM00180
Domain	VWF_A	COL6A3 ITGA11 ITGA10 ITIH5 HMCN2 COL14A1	3.09e-04	99	172	6	IPR002035
Domain	VWFC_1	COL3A1 KCP PXDNL MUC5AC	3.25e-04	36	172	4	PS01208
Domain	ig	BOC FCRL2 OBSCN OBSL1 FCRL3 CNTN5 SIGLEC1 FCRL5	3.86e-04	190	172	8	PF00047
Domain	Immunoglobulin	BOC FCRL2 OBSCN OBSL1 FCRL3 CNTN5 SIGLEC1 FCRL5	3.86e-04	190	172	8	IPR013151
Domain	VWF_type-D	KCP FCGBP MUC5AC	3.94e-04	16	172	3	IPR001846
Domain	VWFD	KCP FCGBP MUC5AC	3.94e-04	16	172	3	PS51233
Domain	VWD	KCP FCGBP MUC5AC	3.94e-04	16	172	3	SM00216
Domain	VWD	KCP FCGBP MUC5AC	3.94e-04	16	172	3	PF00094
Domain	VWFC_2	COL3A1 KCP PXDNL MUC5AC	4.02e-04	38	172	4	PS50184
Domain	LAM_G_DOMAIN	LAMA3 FAT2 CNTNAP5 CELSR2	4.02e-04	38	172	4	PS50025
Domain	Laminin_EGF	STAB2 LAMA3 CELSR2 MEGF11	4.02e-04	38	172	4	IPR002049
Domain	Laminin_G_2	LAMA3 FAT2 CNTNAP5 CELSR2	4.90e-04	40	172	4	PF02210
Domain	G2F	HMCN2 NID1	5.00e-04	4	172	2	PF07474
Domain	NIDOGEN_G2	HMCN2 NID1	5.00e-04	4	172	2	PS50993
Domain	GPR40-rel_orph	FFAR3 GPR42	5.00e-04	4	172	2	IPR013312
Domain	MAPKKKK	MAP4K3 MAP4K2	5.00e-04	4	172	2	IPR021160
Domain	GFP	HMCN2 NID1	5.00e-04	4	172	2	IPR009017
Domain	G2_nidogen/fibulin_G2F	HMCN2 NID1	5.00e-04	4	172	2	IPR006605
Domain	Ig_2	FCRL2 FCRL3 CNTN5 SIGLEC1 FCRL5	5.66e-04	73	172	5	PF13895
Domain	VWC_out	KCP FCGBP MUC5AC	6.67e-04	19	172	3	SM00215
Domain	LamG	LAMA3 FAT2 CNTNAP5 CELSR2	7.07e-04	44	172	4	SM00282
Domain	EGF_CA	STAB2 CUBN FAT2 HMCN2 CELSR2 NID1	9.36e-04	122	172	6	SM00179
Domain	EGF-like_Ca-bd_dom	STAB2 CUBN FAT2 HMCN2 CELSR2 NID1	1.02e-03	124	172	6	IPR001881
Domain	EGF	HGFAC STAB2 CUBN FAT2 CELSR2 NID1	1.11e-03	126	172	6	PF00008
Domain	-	EVPL MACF1	1.23e-03	6	172	2	3.90.1290.10
Domain	-	IGF2R OS9	1.23e-03	6	172	2	2.70.130.10
Domain	Plectin	EVPL MACF1	1.72e-03	7	172	2	PF00681
Domain	Plectin_repeat	EVPL MACF1	1.72e-03	7	172	2	IPR001101
Domain	PLEC	EVPL MACF1	1.72e-03	7	172	2	SM00250
Domain	WD40_repeat_dom	DMXL2 TBL1Y BCAS3 DTL FBXW4 PEX7 PIK3R4 STRN TENM3	1.77e-03	297	172	9	IPR017986
Domain	Kelch	KLHL25 KLHL33 KLHL17 KLHL4	2.00e-03	58	172	4	SM00612
Domain	BACK	KLHL25 KLHL33 KLHL17 KLHL4	2.27e-03	60	172	4	SM00875
Domain	Man6P_isomerase_rcpt-bd_dom	IGF2R OS9	2.28e-03	8	172	2	IPR009011
Domain	Spectrin_repeat	KALRN EVPL MACF1	2.35e-03	29	172	3	IPR002017
Domain	BACK	KLHL25 KLHL33 KLHL17 KLHL4	2.41e-03	61	172	4	IPR011705
Domain	BACK	KLHL25 KLHL33 KLHL17 KLHL4	2.41e-03	61	172	4	PF07707
Domain	Ig_V-set	IGSF8 BOC FCRL2 OBSCN JAML TREM2 SIGLEC1	2.50e-03	199	172	7	IPR013106
Domain	EGF_LAM_2	STAB2 LAMA3 CELSR2	2.60e-03	30	172	3	PS50027
Domain	EGF_LAM_1	STAB2 LAMA3 CELSR2	2.60e-03	30	172	3	PS01248
Domain	WD40	DMXL2 TBL1Y BCAS3 DTL FBXW4 PEX7 PIK3R4 STRN	2.81e-03	259	172	8	PF00400
Domain	LisH	RANBP10 TBL1Y	2.91e-03	9	172	2	PF08513
Domain	WD40	DMXL2 TBL1Y BCAS3 DTL FBXW4 PEX7 PIK3R4 STRN	3.46e-03	268	172	8	SM00320
Domain	WD40_repeat	DMXL2 TBL1Y BCAS3 DTL FBXW4 PEX7 PIK3R4 STRN	3.78e-03	272	172	8	IPR001680
Domain	Kelch_1	KLHL25 KLHL33 KLHL17 KLHL4	3.97e-03	70	172	4	PF01344
Pathway	PID_INTEGRIN1_PATHWAY	IGSF8 COL3A1 COL6A3 ITGA11 ITGA10 LAMA3 NID1	3.23e-06	66	136	7	M18
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 PRSS1 COL6A3 PRSS2 ITGA11 ITGA10 LPA NID1 COL14A1 KLKB1 PCOLCE	4.04e-05	258	136	11	MM14572
Pathway	REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS	ENTPD7 ENTPD4 ENTPD2	4.75e-05	8	136	3	M27737
Pathway	REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS	ENTPD7 ENTPD4 ENTPD2	4.75e-05	8	136	3	MM15486
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL3A1 PRSS1 COL6A3 PRSS2 LAMA3 NID1 COL14A1 KLKB1	6.26e-05	140	136	8	M587
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL3A1 PRSS1 COL6A3 PRSS2 LPA NID1 KLKB1	1.16e-04	114	136	7	MM14571
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 PRSS1 COL6A3 PRSS2 ITGA11 ITGA10 LAMA3 NID1 COL14A1 KLKB1 PCOLCE	1.55e-04	300	136	11	M610
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL3A1 COL6A3 LAMA3 COL14A1 PCOLCE	2.99e-04	61	136	5	M27103
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	IGSF8 BOC FCRL2 KALRN SPEG OBSCN OBSL1 JAML IGDCC4 FAM187B LRFN4 PTPRA CNTN5 SIGLEC1	1.44e-13	162	178	14	25826454
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL3A1 PRSS1 COL6A3 PRSS2 LAMA3 CELA2B F2 HMCN2 LPA NID1 COL14A1	1.92e-09	175	178	11	28071719
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL3A1 COL6A3 LAMA3 COLQ ITIH5 SRPX2 HMCN2 LPA NID1 COL14A1	1.69e-08	167	178	10	22159717
Pubmed	Activation of the zymogen of hepatocyte growth factor activator by thrombin.	HGFAC F2 KLKB1	1.32e-07	3	178	3	8226803
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS1 PRSS2 PRSS3P2	1.32e-07	3	178	3	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS1 PRSS2 PRSS3P2	1.32e-07	3	178	3	9732462
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 RANBP10 KALRN BCAS3 SPEG FBXL14 OBSCN POLRMT PFAS IGF2R KLHL25 CELSR2 NEK8 ENTPD2 TLN2 KAZALD1 LTK TTC5 TOP3B GAREM1 KLHL17	2.67e-07	1105	178	21	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP10 DMXL2 KALRN TBL1Y TBC1D5 GOLGA6A CRMP1 ARF5 STRN CNTNAP5 IGF2R SF3B1 CELSR2 NFATC3 MACF1 TLN2 BSN TOP3B PCDH8	5.90e-07	963	178	19	28671696
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IGSF8 PRSS1 FLNB DMXL2 KALRN MAP4K3 BCAS3 CMAS LANCL2 CRMP1 ARF4 ARF5 PIK3R4 JUP STRN PTPRA SF3B1 SLC27A1 MACF1 TLN2 HADHB BSN HSPA2	1.27e-06	1431	178	23	37142655
Pubmed	Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.	FCRL2 FCRL3 FCRL5	1.31e-06	5	178	3	18704934
Pubmed	Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia.	FCRL2 FCRL3 FCRL5	1.31e-06	5	178	3	16849395
Pubmed	IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.	FCRL2 FCRL3 FCRL5	1.31e-06	5	178	3	11929751
Pubmed	Identification of a family of Fc receptor homologs with preferential B cell expression.	FCRL2 FCRL3 FCRL5	1.31e-06	5	178	3	11493702
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	PRSS1 FLNB PRSS2 ITGA11 OBSCN FLG2 JUP IGF2R NEK8 ZNF561 HADHB MUC5AC HSPA2 KLHL4	1.42e-06	564	178	14	21565611
Pubmed	An investigation into the human serum "interactome".	PRSS1 KIAA0232 OBSL1 F2 IGDCC4 PRSS3P2 MACF1 TLN2	2.03e-06	162	178	8	15174051
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP6 NPC1 FLNB DMXL2 KALRN OBSL1 FBXW4 CMAS CRMP1 PIK3R4 METAP1 PTPRA SF3B1 TMEM168 SERGEF MACF1 TLN2 USPL1 HSPA2 GEN1 KLHL4	2.95e-06	1285	178	21	35914814
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	BOC OCA2 ALX4 IGF2R	7.71e-06	25	178	4	29475039
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL3A1 COL6A3 LAMA3 HMCN2 NID1 COL14A1 PCOLCE	1.09e-05	146	178	7	27068509
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL3A1 COL6A3 COLQ ITIH5 SRPX2 NID1 COL14A1	1.48e-05	153	178	7	25037231
Pubmed	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.	KLK6 EVPL FLG2 JUP LORICRIN	1.70e-05	62	178	5	26644517
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	NPC1 FLNB COL6A3 KALRN ENPP3 GPT EVPL LAMP2 CUBN GFRA1 JUP FCGBP IGF2R TMPRSS11D PKHD1 NID1 HSPA2	2.04e-05	1016	178	17	19056867
Pubmed	Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.	LAMA3 NKX2-1 NID1	2.11e-05	11	178	3	12051813
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	NPC1 LAMA3 LAMP2 IGF2R ENTPD2 OS9 CHPF2	2.31e-05	164	178	7	32409323
Pubmed	Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.	FFAR3 GPR42	2.60e-05	2	178	2	25637492
Pubmed	Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.	FFAR3 GPR42	2.60e-05	2	178	2	30478340
Pubmed	Molecular basis of oculocutaneous albinism.	OCA2 TYR	2.60e-05	2	178	2	7963676
Pubmed	The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase.	OCA2 TYR	2.60e-05	2	178	2	12028586
Pubmed	Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.	FFAR3 GPR42	2.60e-05	2	178	2	35858247
Pubmed	Oculocutaneous albinism (OCA) in Colombia: first molecular screening of the TYR and OCA2 genes in South America.	OCA2 TYR	2.60e-05	2	178	2	25455140
Pubmed	The Linkage of Dark-Eye and Color in Mice.	OCA2 TYR	2.60e-05	2	178	2	17246260
Pubmed	Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.	FFAR3 GPR42	2.60e-05	2	178	2	22506074
Pubmed	Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.	PRSS1 PRSS3P2	2.60e-05	2	178	2	11702203
Pubmed	Variations of Linkage in Rats and Mice.	OCA2 TYR	2.60e-05	2	178	2	17246029
Pubmed	Linkage of a Dilute Color Factor and Dark-Eye in Mice.	OCA2 TYR	2.60e-05	2	178	2	17246039
Pubmed	The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.	FFAR3 GPR42	2.60e-05	2	178	2	24748202
Pubmed	Linkage of Albino Allelomorphs in Rats and Mice.	OCA2 TYR	2.60e-05	2	178	2	17246054
Pubmed	Genetic basis of susceptibility to splenic lipofuscinosis in mice.	OCA2 TYR	2.60e-05	2	178	2	7117836
Pubmed	The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.	FFAR3 GPR42	2.60e-05	2	178	2	36362376
Pubmed	Genetic Causes of Oculocutaneous Albinism in Pakistani Population.	OCA2 TYR	2.60e-05	2	178	2	33800529
Pubmed	Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.	OBSCN MYBPC3	2.60e-05	2	178	2	19403693
Pubmed	Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.	FFAR3 GPR42	2.60e-05	2	178	2	20399779
Pubmed	Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.	PRSS1 PRSS2	2.60e-05	2	178	2	36191639
Pubmed	Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.	FFAR3 GPR42	2.60e-05	2	178	2	23110765
Pubmed	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	FFAR3 GPR42	2.60e-05	2	178	2	26522986
Pubmed	Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.	FFAR3 GPR42	2.60e-05	2	178	2	27664183
Pubmed	Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.	PRSS1 PRSS2	2.60e-05	2	178	2	33202925
Pubmed	Effects of ETV5 (ets variant gene 5) on testis and body growth, time course of spermatogonial stem cell loss, and fertility in mice.	ETV5 GFRA1	2.60e-05	2	178	2	18032421
Pubmed	Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.	PRSS1 PRSS2	2.60e-05	2	178	2	20484960
Pubmed	G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.	FFAR3 GPR42	2.60e-05	2	178	2	37019194
Pubmed	A novel P gene missense mutation in a Japanese patient with oculocutaneous albinism type II (OCA2).	OCA2 TYR	2.60e-05	2	178	2	12727022
Pubmed	3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.	FFAR3 GPR42	2.60e-05	2	178	2	38040866
Pubmed	Interaction properties of the procollagen C-proteinase enhancer protein shed light on the mechanism of stimulation of BMP-1.	COL3A1 PCOLCE	2.60e-05	2	178	2	12105202
Pubmed	Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.	FFAR3 GPR42	2.60e-05	2	178	2	35408893
Pubmed	FFAR3 modulates insulin secretion and global gene expression in mouse islets.	FFAR3 GPR42	2.60e-05	2	178	2	26091414
Pubmed	Germline and somatic albinism variants in amelanotic/hypomelanotic melanoma: Increased carriage of TYR and OCA2 variants.	OCA2 TYR	2.60e-05	2	178	2	32966289
Pubmed	Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.	PRSS1 PRSS3P2	2.60e-05	2	178	2	25546417
Pubmed	GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.	FFAR3 GPR42	2.60e-05	2	178	2	27550964
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	2.60e-05	2	178	2	15185077
Pubmed	Prenatal molecular diagnosis of oculocutaneous albinism (OCA) in a large cohort of Israeli families.	OCA2 TYR	2.60e-05	2	178	2	19626598
Pubmed	Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.	FFAR3 GPR42	2.60e-05	2	178	2	32073900
Pubmed	Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation.	IGF2R BRCA1	2.60e-05	2	178	2	15232000
Pubmed	Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.	PRSS1 PRSS2	2.60e-05	2	178	2	27846138
Pubmed	Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses.	ARF4 ARF5	2.60e-05	2	178	2	22105072
Pubmed	Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).	PRSS1 PRSS2	2.60e-05	2	178	2	14695529
Pubmed	Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.	PRSS1 PRSS2	2.60e-05	2	178	2	15776435
Pubmed	Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.	FFAR3 GPR42	2.60e-05	2	178	2	19630535
Pubmed	Linkage in Mice and Rats.	OCA2 TYR	2.60e-05	2	178	2	17245945
Pubmed	Genetic risk of FCRL3 and FCRL5 polymorphisms in children with asthma and allergic rhinitis in a Chinese Han population.	FCRL3 FCRL5	2.60e-05	2	178	2	30771554
Pubmed	Distinguishing self from nonself: immunogenicity of the murine H47 locus is determined by a single amino acid substitution in an unusual peptide.	OCA2 TYR	2.60e-05	2	178	2	11254699
Pubmed	Tail short variable: characterization of a new mouse mutant, and its possible analogy to certain human vascular disruption defects.	OCA2 TYR	2.60e-05	2	178	2	8278937
Pubmed	Mutational Analysis of the TYR and OCA2 Genes in Four Chinese Families with Oculocutaneous Albinism.	OCA2 TYR	2.60e-05	2	178	2	25919014
Pubmed	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.	FFAR3 GPR42	2.60e-05	2	178	2	14722361
Pubmed	Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.	PRSS1 PRSS2	2.60e-05	2	178	2	18461367
Pubmed	Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.	PRSS1 PRSS2	2.60e-05	2	178	2	15651064
Pubmed	Pink-eyed dilution protein controls the processing of tyrosinase.	OCA2 TYR	2.60e-05	2	178	2	12058062
Pubmed	Immunoreactive anionic and cationic trypsin in human serum.	PRSS1 PRSS2	2.60e-05	2	178	2	2598466
Pubmed	Microdissection and microcloning from the proximal region of mouse chromosome 7: isolation of clones genetically linked to the pudgy locus.	OCA2 TYR	2.60e-05	2	178	2	3319884
Pubmed	Novel and recurrent mutations in the tyrosinase gene and the P gene in the German albino population.	OCA2 TYR	2.60e-05	2	178	2	10987646
Pubmed	Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.	FFAR3 GPR42	2.60e-05	2	178	2	26260360
Pubmed	Inheritance of the macrophage alloantigenic marker (Mph-1) in inbred mice.	OCA2 TYR	2.60e-05	2	178	2	1225761
Pubmed	Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.	PRSS1 PRSS2	2.60e-05	2	178	2	35089416
Pubmed	Kallikrein activates prothrombin.	F2 KLKB1	2.60e-05	2	178	2	18160576
Pubmed	Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.	PRSS1 PRSS2	2.60e-05	2	178	2	18063422
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	BOC FCRL2 HGFAC REG4 JAML ITIH5 TMPRSS3 CHPF2 KAZALD1 FCRL5 SPINK6	2.77e-05	460	178	11	20562862
Pubmed	The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL.	FCRL2 FCRL3 FCRL5	2.80e-05	12	178	3	17273841
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	RANBP10 KALRN GPT OBSCN FLG2 CRY1 STRN FIG4 MYBPC3	2.93e-05	304	178	9	32235678
Pubmed	Assessment of splice variant-specific functions of desmocollin 1 in the skin.	JUP LORICRIN RPTN	3.63e-05	13	178	3	14673151
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL25 KLHL33 KLHL17 KLHL4	5.79e-05	41	178	4	23676014
Pubmed	Functional proteomics mapping of a human signaling pathway.	TTF2 FLNB MRI1 ANKRD27 METAP1 JUP STRN SF3B1 TENM3 MACF1 NID1 OS9	5.83e-05	591	178	12	15231748
Pubmed	Signal peptide prediction based on analysis of experimentally verified cleavage sites.	FCRL2 HGFAC REG4 LAMP2 JAML PIK3IP1 KAZALD1 SPINK6	6.96e-05	264	178	8	15340161
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL3A1 PRSS1 COL6A3 ITIH5 NID1 COL14A1	7.19e-05	135	178	6	28675934
Pubmed	Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.	ARF4 ARF5	7.79e-05	3	178	2	31201232
Pubmed	Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.	PRSS1 PRSS2	7.79e-05	3	178	2	24146905
Pubmed	GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis.	ARF4 ARF5	7.79e-05	3	178	2	22185782
Pubmed	Human and Giardia ADP-ribosylation factors (ARFs) complement ARF function in Saccharomyces cerevisiae.	ARF4 ARF5	7.79e-05	3	178	2	1447192
Pubmed	Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.	PRSS1 PRSS2	7.79e-05	3	178	2	23882137
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	KALRN NLGN1	7.79e-05	3	178	2	31801062
Pubmed	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.	FFAR3 GPR42	7.79e-05	3	178	2	12496283
Pubmed	Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.	ARF4 ARF5	7.79e-05	3	178	2	20921225
Pubmed	Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.	FFAR3 GPR42	7.79e-05	3	178	2	23665276
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC KALRN SPEG OBSCN OBSL1 IGDCC4 LRFN4 HMCN2 PXDNL CNTN5 KAZALD1 SIGLEC1 MYBPC3	5.81e-11	161	121	13	593
GeneFamily	Fibronectin type III domain containing	BOC KALRN OBSCN IGDCC4 LRFN4 CNTN5 COL14A1 OSMR MYBPC3	1.29e-06	160	121	9	555
GeneFamily	Immunoglobulin like domain containing	BOC FCRL2 IL12B OBSL1 IGDCC4 FCRL3 HMCN2 CNTN5 FCRL5	6.03e-06	193	121	9	594
GeneFamily	Proteases, serine	PRSS1 PRSS2 KLK6 TMPRSS3 TMPRSS11D	6.37e-05	63	121	5	738
GeneFamily	Kelch like\|BTB domain containing	KLHL25 KLHL33 KLHL17 KLHL4	1.76e-04	42	121	4	617
GeneFamily	WD repeat domain containing	DMXL2 TBL1Y BCAS3 DTL FBXW4 PEX7 PIK3R4 STRN	3.84e-04	262	121	8	362
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K3 MAP4K2	4.38e-04	5	121	2	655
GeneFamily	CD molecules\|MRH domain containing	IGF2R OS9	6.55e-04	6	121	2	1233
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG2 RPTN	9.13e-04	7	121	2	1350
GeneFamily	EF-hand domain containing\|Plakins	EVPL MACF1	1.21e-03	8	121	2	939
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IGSF8 FCRL2 ENPP3 LAMP2 CR2 FCRL3 IGF2R SIGLEC1 FCRL5	1.34e-03	394	121	9	471
GeneFamily	Collagens	COL3A1 COL6A3 COL14A1	3.60e-03	46	121	3	490
GeneFamily	Kallikreins	KLK6 KLKB1	5.01e-03	16	121	2	616
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA11 ITGA10	6.34e-03	18	121	2	1160
Coexpression	NABA_MATRISOME	COL3A1 IL12B HGFAC PRSS1 COL6A3 PRSS2 REG4 ADAM21 WNT8A KCP LAMA3 HTRA3 CELA2B FLG2 F2 COLQ ITIH5 PIK3IP1 SRPX2 HMCN2 PXDNL RPTN LPA NID1 COL14A1 KAZALD1 MUC5AC MEGF11 PCOLCE	6.34e-11	1026	177	29	M5889
Coexpression	NABA_MATRISOME	COL3A1 IL12B HGFAC PRSS1 COL6A3 PRSS2 REG4 ADAM21 WNT8A KCP LAMA3 HTRA3 CELA2B FLG2 F2 COLQ ITIH5 PIK3IP1 SRPX2 HMCN2 RPTN LPA NID1 COL14A1 KAZALD1 MUC5AC MEGF11 PCOLCE	2.10e-10	1008	177	28	MM17056
Coexpression	NABA_MATRISOME_ASSOCIATED	IL12B HGFAC PRSS1 PRSS2 REG4 ADAM21 WNT8A HTRA3 CELA2B FLG2 F2 ITIH5 PIK3IP1 RPTN LPA KAZALD1 MUC5AC MEGF11	2.87e-06	738	177	18	MM17058
Coexpression	NABA_CORE_MATRISOME	COL3A1 COL6A3 KCP LAMA3 COLQ SRPX2 HMCN2 PXDNL NID1 COL14A1 PCOLCE	2.91e-06	275	177	11	M5884
Coexpression	NABA_MATRISOME_ASSOCIATED	IL12B HGFAC PRSS1 PRSS2 REG4 ADAM21 WNT8A HTRA3 CELA2B FLG2 F2 ITIH5 PIK3IP1 RPTN LPA KAZALD1 MUC5AC MEGF11	3.66e-06	751	177	18	M5885
Coexpression	GSE6875_TCONV_VS_TREG_UP	AKAP6 HGFAC DCBLD1 PRND ALX4 STRN SLC27A1 NID1 TOP3B	8.56e-06	198	177	9	M6799
Coexpression	NABA_CORE_MATRISOME	COL3A1 COL6A3 KCP LAMA3 COLQ SRPX2 HMCN2 NID1 COL14A1 PCOLCE	1.62e-05	270	177	10	MM17057
Coexpression	NABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS	PRSS1 PRSS2 CELA2B F2	2.68e-05	26	177	4	MM17051
Coexpression	VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	COL3A1 COL6A3 JUP IGF2R NID1	3.21e-05	54	177	5	M4737
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 ADAM21 HTRA3 CELA2B F2 ITIH5 LPA KAZALD1	3.68e-05	238	177	9	M3468
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 ADAM21 HTRA3 CELA2B F2 ITIH5 LPA KAZALD1	4.19e-05	242	177	9	MM17062
Coexpression	NABA_ECM_GLYCOPROTEINS	KCP LAMA3 COLQ SRPX2 HMCN2 PXDNL NID1 PCOLCE	5.87e-05	196	177	8	M3008
Coexpression	BENPORATH_ES_WITH_H3K27ME3	FBXL14 HTRA3 EVX1 OCA2 SIM1 FAM43B CR2 ANKRD27 ALX4 CRMP1 ITIH5 CRYBA2 CNTNAP5 NKX2-1 ENTPD2 KAZALD1 LTK PCDH8 SLC30A10 KLHL17	6.93e-05	1115	177	20	M10371
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR	COL3A1 F2 NID1 COL14A1	8.94e-05	35	177	4	MM17054
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	ETV5 TRANK1 COL14A1 KAZALD1 ATP1B2 PCOLCE	2.51e-05	72	171	6	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	COL3A1 COL6A3 KALRN DTL ETV5 CRY1 CNTNAP5 TENM3 LORICRIN COL14A1 ATP1B2 KLHL4 PCOLCE	3.58e-05	418	171	13	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_200	COL14A1 KAZALD1 ATP1B2 PCOLCE	3.80e-05	24	171	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_200
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 BOC COL6A3 ITGA11 HTRA3 NLGN1 GFRA1 IGDCC4 SRPX2 ENTPD2 COL14A1 PCOLCE	2.86e-11	199	177	12	6e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 PCOLCE	3.38e-10	192	177	11	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 KCP HTRA3 GFRA1 ITIH5 SRPX2 ENTPD2 NID1 PCOLCE	3.38e-10	192	177	11	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 KCP HTRA3 GFRA1 ITIH5 SRPX2 ENTPD2 NID1 PCOLCE	3.38e-10	192	177	11	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 PCOLCE	3.38e-10	192	177	11	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 PCOLCE	3.38e-10	192	177	11	ac1477433704573f95111eee6263b93668d2845e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL3A1 BOC COL6A3 HTRA3 NLGN1 GFRA1 IGDCC4 NID1 COL14A1 TLN2 PCOLCE	3.57e-10	193	177	11	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL3A1 BOC HTRA3 NLGN1 GFRA1 IGDCC4 HMCN2 ENTPD2 COL14A1 TLN2 PCOLCE	3.77e-10	194	177	11	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COL3A1 BOC COL6A3 OBSL1 HTRA3 GFRA1 SRPX2 NID1 COL14A1 OSMR PCOLCE	4.44e-10	197	177	11	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COL3A1 BOC COL6A3 OBSL1 HTRA3 GFRA1 SRPX2 NID1 COL14A1 OSMR PCOLCE	4.44e-10	197	177	11	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COL3A1 BOC COL6A3 OBSL1 HTRA3 GFRA1 SRPX2 NID1 COL14A1 OSMR PCOLCE	4.44e-10	197	177	11	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	distal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 BOC COL6A3 ITGA11 HTRA3 GFRA1 IGDCC4 SRPX2 ENTPD2 COL14A1 PCOLCE	4.94e-10	199	177	11	547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 BOC COL6A3 HTRA3 NLGN1 GFRA1 SRPX2 NID1 COL14A1 TLN2 PCOLCE	5.21e-10	200	177	11	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 BOC COL6A3 ITGA11 HTRA3 FAM43B GFRA1 IGDCC4 ENTPD2 COL14A1 PCOLCE	5.21e-10	200	177	11	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL6A3 ITGA11 HTRA3 NLGN1 GFRA1 ITIH5 SRPX2 NID1 COL14A1 PCOLCE	5.21e-10	200	177	11	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 BOC ITGA11 ITGA10 GFRA1 IGDCC4 SRPX2 TENM3 KAZALD1 OSMR PCOLCE	5.21e-10	200	177	11	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL6A3 ITGA11 HTRA3 NLGN1 GFRA1 ITIH5 SRPX2 NID1 COL14A1 PCOLCE	5.21e-10	200	177	11	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 BOC ITGA11 ITGA10 GFRA1 IGDCC4 SRPX2 TENM3 KAZALD1 OSMR PCOLCE	5.21e-10	200	177	11	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 PAQR6 IGDCC4 ENTPD2 NID1 COL14A1 KAZALD1	4.04e-09	186	177	10	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL3A1 BOC COL6A3 HTRA3 SRPX2 IGF2R MACF1 NID1 COL14A1 PCOLCE	4.48e-09	188	177	10	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 BOC COL6A3 HTRA3 ARF4 IGDCC4 ENTPD2 NID1 COL14A1 PCOLCE	4.96e-09	190	177	10	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 BOC COL6A3 HTRA3 ITIH5 TENM3 ENTPD2 NID1 COL14A1 PCOLCE	5.22e-09	191	177	10	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 KCP HTRA3 GFRA1 ITIH5 SRPX2 ENTPD2 NID1 PCOLCE	5.22e-09	191	177	10	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 BOC COL6A3 HTRA3 ITIH5 TENM3 ENTPD2 NID1 COL14A1 PCOLCE	5.22e-09	191	177	10	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	5.49e-09	192	177	10	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 BOC COL6A3 HTRA3 FAM43B GFRA1 ITIH5 SRPX2 COL14A1 PCOLCE	5.49e-09	192	177	10	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	5.49e-09	192	177	10	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	5.49e-09	192	177	10	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL3A1 BOC COL6A3 HTRA3 NLGN1 GFRA1 IGDCC4 COL14A1 TLN2 PCOLCE	5.49e-09	192	177	10	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 HTRA3 GFRA1 ITIH5 SRPX2 ENTPD2 COL14A1 KAZALD1 PCOLCE	5.77e-09	193	177	10	ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 PCOLCE	5.77e-09	193	177	10	160691b671710be10220803d788c2c961c236af1
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 HTRA3 GFRA1 ITIH5 SRPX2 ENTPD2 COL14A1 KAZALD1 PCOLCE	5.77e-09	193	177	10	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 KAZALD1 PCOLCE	6.06e-09	194	177	10	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 KAZALD1 PCOLCE	6.06e-09	194	177	10	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 KAZALD1 PCOLCE	6.06e-09	194	177	10	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 FAM43B GFRA1 PXDNL NID1 COL14A1 PCOLCE	7.02e-09	197	177	10	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 BOC COL6A3 HTRA3 TENM3 ENTPD2 COL14A1 KAZALD1 PCDH8 PCOLCE	7.37e-09	198	177	10	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 GFRA1 IGDCC4 PXDNL NID1 COL14A1 PCOLCE	7.73e-09	199	177	10	9672230aa0bc6a7289050c955f5154ca183a5159
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 GFRA1 IGDCC4 PXDNL NID1 COL14A1 PCOLCE	7.73e-09	199	177	10	e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell	distal-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 BOC COL6A3 HTRA3 FAM43B GFRA1 SRPX2 TENM3 COL14A1 PCOLCE	7.73e-09	199	177	10	97b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL3A1 COL6A3 ITIH5 PXDNL LPA MACF1 NID1 COL14A1 OSMR PCOLCE	8.11e-09	200	177	10	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 FAM43B GFRA1 SRPX2 NID1 COL14A1 PCOLCE	8.11e-09	200	177	10	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL3A1 COL6A3 ITIH5 PXDNL LPA MACF1 NID1 COL14A1 ATP1B2 PCOLCE	8.11e-09	200	177	10	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A3 JAML ALX4 ITIH5 SRPX2 NID1 KAZALD1 PCOLCE	1.58e-08	159	177	9	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	4.61e-08	180	177	9	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	AKAP6 COL3A1 ITGA11 KALRN SPEG NLGN1 PXDNL COL14A1 TLN2	4.61e-08	180	177	9	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 GFRA1 PXDNL NID1 COL14A1 PCOLCE	5.07e-08	182	177	9	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 TMEM121B HTRA3 ITIH5 ENTPD2 NID1 PCOLCE	5.32e-08	183	177	9	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 TMEM121B HTRA3 ITIH5 ENTPD2 NID1 PCOLCE	5.32e-08	183	177	9	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 TMEM121B HTRA3 ITIH5 ENTPD2 NID1 PCOLCE	5.32e-08	183	177	9	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL3A1 BOC ITGA11 HTRA3 GFRA1 IGDCC4 SRPX2 NID1 KLHL33	5.57e-08	184	177	9	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 PAQR6 ALX4 ENTPD2 NID1 COL14A1	5.84e-08	185	177	9	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 PAQR6 ALX4 ENTPD2 NID1 COL14A1	5.84e-08	185	177	9	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 BOC COL6A3 ITGA11 KCP IGDCC4 SRPX2 TLN2 PCOLCE	6.11e-08	186	177	9	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 BOC COL6A3 ITGA11 KCP IGDCC4 SRPX2 TLN2 PCOLCE	6.11e-08	186	177	9	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A3 HTRA3 JAML ITIH5 SRPX2 NID1 PCOLCE	6.69e-08	134	177	8	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC ITGA11 HTRA3 PAQR6 ENTPD2 NID1 COL14A1 PCOLCE	7.01e-08	189	177	9	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 BOC COL6A3 HTRA3 GFRA1 IGDCC4 NID1 COL14A1 PCOLCE	7.01e-08	189	177	9	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC ITGA11 HTRA3 PAQR6 ENTPD2 NID1 COL14A1 PCOLCE	7.01e-08	189	177	9	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 COL6A3 GFRA1 IGDCC4 TENM3 PXDNL COL14A1 OSMR PCOLCE	7.67e-08	191	177	9	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 BOC COL6A3 HTRA3 IGDCC4 ENTPD2 NID1 COL14A1 PCOLCE	7.67e-08	191	177	9	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL3A1 BOC HTRA3 NLGN1 GFRA1 IGDCC4 HMCN2 COL14A1 PCOLCE	8.02e-08	192	177	9	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	8.02e-08	192	177	9	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ENPP3 HTRA3 ENTPD2 NID1 COL14A1 PCOLCE	8.02e-08	192	177	9	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 OSMR PCOLCE	8.02e-08	192	177	9	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL3A1 BOC COL6A3 NLGN1 GFRA1 IGDCC4 COL14A1 TLN2 PCOLCE	8.02e-08	192	177	9	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 OSMR PCOLCE	8.02e-08	192	177	9	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 COL6A3 HTRA3 ITIH5 TENM3 ENTPD2 NID1 COL14A1 PCOLCE	8.02e-08	192	177	9	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ENPP3 HTRA3 ENTPD2 NID1 COL14A1 PCOLCE	8.02e-08	192	177	9	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	8.02e-08	192	177	9	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 OSMR PCOLCE	8.02e-08	192	177	9	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	COL3A1 BOC COL6A3 ITGA11 NLGN1 GFRA1 IGDCC4 NID1 COL14A1	8.02e-08	192	177	9	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 COL14A1 OSMR	8.02e-08	192	177	9	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 COL3A1 COL6A3 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 PCOLCE	8.02e-08	192	177	9	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 HTRA3 GFRA1 SRPX2 HMCN2 TENM3 ATP1B2 HSPA2 PCDH8	8.39e-08	193	177	9	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ENPP3 HTRA3 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 COL6A3 HTRA3 ITIH5 TENM3 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 COL3A1 COL6A3 HTRA3 ITIH5 SRPX2 ENTPD2 NID1 PCOLCE	8.39e-08	193	177	9	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 ITGA11 HTRA3 GFRA1 ITIH5 ENTPD2 COL14A1 PCOLCE	8.39e-08	193	177	9	64edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	8.39e-08	193	177	9	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 COL6A3 GFRA1 IGDCC4 TENM3 PXDNL COL14A1 OSMR PCOLCE	8.76e-08	194	177	9	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL6A3 ITGA11 HTRA3 GFRA1 IGDCC4 ENTPD2 COL14A1 PCOLCE	8.76e-08	194	177	9	35b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL6A3 ITGA11 KALRN GFRA1 SRPX2 TENM3 NID1 COL14A1	8.76e-08	194	177	9	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	9.16e-08	195	177	9	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL3A1 BOC COL6A3 ITIH5 SRPX2 TENM3 NID1 COL14A1 PCOLCE	9.16e-08	195	177	9	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL6A3 ITGA11 KALRN GFRA1 SRPX2 TENM3 NID1 COL14A1	9.16e-08	195	177	9	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL6A3 ITGA11 KALRN GFRA1 SRPX2 TENM3 NID1 COL14A1	9.16e-08	195	177	9	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL3A1 BOC COL6A3 ITIH5 SRPX2 TENM3 NID1 COL14A1 PCOLCE	9.16e-08	195	177	9	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL3A1 BOC COL6A3 ITGA11 GFRA1 SRPX2 TENM3 NID1 OSMR	9.16e-08	195	177	9	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	facs-GAT-Fat-3m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	9.16e-08	195	177	9	1cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 HTRA3 ITIH5 ENTPD2 NID1 COL14A1 PCOLCE	9.16e-08	195	177	9	9cef6f18664518060af7c192310dddce6d70345a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL6A3 ITGA11 KALRN SPEG HMCN2 CNTN5 NID1 COL14A1	9.57e-08	196	177	9	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL6A3 ITGA11 KALRN SPEG HMCN2 CNTN5 NID1 COL14A1	9.57e-08	196	177	9	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 BOC COL6A3 ENPP3 HTRA3 LAMP2 ENTPD2 NID1 COL14A1	9.57e-08	196	177	9	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 TENM3 ENTPD2 COL14A1 PCOLCE	9.57e-08	196	177	9	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL6A3 ITGA11 HTRA3 ITIH5 TENM3 ENTPD2 COL14A1 PCOLCE	9.57e-08	196	177	9	34020d6553309daa269dff05de0a8567211ea4d2
Drug	Bvpam	BOC PRSS1 PRSS2 F2 TYR KLKB1	9.33e-09	21	175	6	CID000125185
Drug	Db04336	PRSS1 PRSS2 F2 KLKB1	5.00e-08	6	175	4	CID000002014
Drug	4Amf	PRSS1 PRSS2 F2 KLKB1	4.12e-07	9	175	4	CID000150955
Drug	FK-401	PRSS1 PRSS2 F2 KLKB1	4.12e-07	9	175	4	CID000135041
Drug	diisopropylamine	BOC PRSS1 PRSS2 ENPP3 GOLGA6A KLKB1	5.85e-07	40	175	6	CID000007912
Drug	4-ethylpiperidine	PRSS1 PRSS2 F2	1.78e-06	4	175	3	CID000076704
Drug	NSC-13568	PRSS1 PRSS2 F2	1.78e-06	4	175	3	CID000224783
Drug	NSC-45351	PRSS1 PRSS2 F2	1.78e-06	4	175	3	CID000018046
Drug	phenyl 4-guanidinobenzoate	PRSS1 PRSS2 F2 KLKB1	2.28e-06	13	175	4	CID003015798
Drug	N-acetylhexosamine	IL12B HGFAC PRSS1 PRSS2 ITGA11 REG4 GPT ITGA10 NLGN1 CMAS GFRA1 PIK3R4 IGF2R ALDOB MUC5AC	3.97e-06	472	175	15	CID000000899
Drug	ONO-3307	PRSS1 PRSS2 F2 KLKB1	4.31e-06	15	175	4	CID000127139
Drug	BAME	PRSS1 PRSS2 ETV5 F2 KLKB1	4.31e-06	32	175	5	CID000150869
Drug	4-TGPAP	PRSS1 PRSS2 F2	4.41e-06	5	175	3	CID000132086
Drug	PTA-Arg	PRSS1 PRSS2 F2	4.41e-06	5	175	3	CID000194378
Drug	2,6-diphenoxypyridine	PRSS1 PRSS2 F2	4.41e-06	5	175	3	CID000824772
Drug	Ile-Phe-Lys-CH2Cl	PRSS1 PRSS2 KLKB1	4.41e-06	5	175	3	CID000124393
Drug	PTA-GPA	PRSS1 PRSS2 F2	4.41e-06	5	175	3	CID000139330
Drug	6-amidinoindole	PRSS1 PRSS2 F2	4.41e-06	5	175	3	CID003018291
Drug	FFRck	PRSS1 PRSS2 KLK6 F2 KLKB1	5.88e-06	34	175	5	CID000126484
Drug	cyanogen-bromide	COL3A1 BOC PRSS1 PRSS2 KLKB1	5.88e-06	34	175	5	CID000010476
Drug	(1S,2R)-1-amino-1-thiazolidin-2-yl-propan-2-ol	COL3A1 MKKS BOC COL6A3 ENPP3 PRND METAP1	6.14e-06	90	175	7	CID015942693
Drug	Tosylarginine Methyl Ester	PRSS1 PRSS2 F2 KLKB1	7.42e-06	17	175	4	CID000013481
Drug	4-TAPAP	PRSS1 PRSS2 F2	8.78e-06	6	175	3	CID000133476
Drug	CHCl	BOC PRSS1 PRSS2 KLK6 F2 KLKB1	1.07e-05	65	175	6	CID006432229
Drug	b-Ti	PRSS1 PRSS2 CRY1 SGMS1	1.19e-05	19	175	4	CID011840927
Drug	S2266	PRSS1 PRSS2 KLK6 F2 KLKB1	1.34e-05	40	175	5	CID000122333
Drug	S 2251	PRSS1 PRSS2 F2 LPA KLKB1	1.34e-05	40	175	5	CID000124997
Drug	0ZI	BOC PRSS1 PRSS2 F2	1.48e-05	20	175	4	CID000122235
Drug	S 2160	PRSS1 PRSS2 F2 KLKB1	1.48e-05	20	175	4	CID000189147
Drug	Phe-pro-arg	BOC PRSS1 PRSS2 PRND F2	1.52e-05	41	175	5	CID000133189
Drug	NPGB	PRSS1 PRSS2 F2 TYR KLKB1	1.52e-05	41	175	5	CID000030744
Drug	Kki 8	PRSS1 PRSS2 KLKB1	1.53e-05	7	175	3	CID000064584
Drug	bz-Ar	PRSS1 PRSS2 F2	1.53e-05	7	175	3	CID000137302
Drug	Arg-OEt	BOC PRSS1 PRSS2	1.53e-05	7	175	3	CID000439495
Drug	Cbz-phe-arg-chn2	PRSS1 PRSS2 KLKB1	1.53e-05	7	175	3	CID005492392
Drug	Z-Glu-Tyr	PRSS1 PRSS2 ALDOB	1.53e-05	7	175	3	CID000096820
Drug	Kki 7	PRSS1 PRSS2 KLKB1	1.53e-05	7	175	3	CID003082667
Drug	EACA	HGFAC PRSS1 PRSS2 KLK6 F2 CRY1 LPA KLKB1	2.27e-05	151	175	8	CID000000564
Drug	Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	AKAP6 HGFAC KALRN PIK3IP1 ENTPD2 COL14A1 TLN2 PCDH8 KLHL4	2.36e-05	198	175	9	4230_UP
Drug	HMTi	PRSS1 PRSS2 TMPRSS11D	2.43e-05	8	175	3	CID000195636
Drug	AC1NDMP4	PRSS1 PRSS2 F2	2.43e-05	8	175	3	CID004628293
Drug	Bio-Phe-CH2Cl	PRSS1 PRSS2 F2	2.43e-05	8	175	3	CID000083924
Drug	Bio-Arg-CH2Cl	PRSS1 PRSS2 F2	2.43e-05	8	175	3	CID000083923
Drug	Boc hydrazine	BOC PRSS1 PRSS2	2.43e-05	8	175	3	CID000070091
Drug	PPACK	COL3A1 PRSS1 COL6A3 PRSS2 PRND F2 COL14A1	2.74e-05	113	175	7	CID003036757
Drug	8-azaguanine	COL3A1 COL6A3 ENPP3 UGT1A1 TMPRSS11D LTK	3.07e-05	78	175	6	CID000008646
Drug	APMSF	BOC PRSS1 PRSS2 F2 TYR	3.32e-05	48	175	5	CID000001719
Drug	PtdIns(3,5)P	PRSS1 PRSS2 TBL1Y	3.62e-05	9	175	3	CID000643961
Drug	p-guanidino-L-phenylalanine	PRSS1 PRSS2 F2	3.62e-05	9	175	3	CID000165028
Drug	tlmE	PRSS1 PRSS2 F2	3.62e-05	9	175	3	CID000188322
Drug	dansyl-L-arginine	PRSS1 PRSS2 F2	3.62e-05	9	175	3	CID000119895
Drug	Sialic acids	COL3A1 PRSS1 PRSS2 REG4 LAMP2 NLGN1 CMAS LPA SIGLEC1 ALDOB MUC5AC	5.08e-05	329	175	11	CID000349960
Drug	TAPAP	PRSS1 PRSS2 F2	5.15e-05	10	175	3	CID000126363
Drug	tert-butylcatechol	PRSS1 PRSS2 TYR	5.15e-05	10	175	3	CID000077643
Drug	SR 26831	PRSS1 PRSS2 F2	5.15e-05	10	175	3	CID000132270
Drug	LMWH	COL3A1 BOC IL12B PRSS1 COL6A3 PRSS2 KLK6 POLRMT LAMA3 F2 PIK3IP1 LPA TMPRSS11D COL14A1 CHPF2 KLKB1	5.60e-05	663	175	16	CID000000772
Drug	pMEU	ETV5 TYR	5.87e-05	2	175	2	CID000451930
Drug	Hemi-Babim	PRSS1 F2	5.87e-05	2	175	2	DB01767
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB07131
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB07091
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB07095
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB07088
Drug	2-NAPHTHALENESULFONIC ACID	PRSS1 F2	5.87e-05	2	175	2	DB08254
Drug	hydrazinoacetic acid	BOC LANCL2	5.87e-05	2	175	2	CID000084227
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB06850
Drug	N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	PRSS1 F2	5.87e-05	2	175	2	DB06853
Drug	N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	PRSS1 F2	5.87e-05	2	175	2	DB06858
Drug	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide	PRSS1 F2	5.87e-05	2	175	2	DB06845
Drug	S 2366	PRSS1 PRSS2 F2 KLKB1	6.89e-05	29	175	4	CID000126364
Drug	Mephe-pro-arg	BOC PRND F2	7.04e-05	11	175	3	CID000133064
Drug	L-Phe-pro	BOC PRSS1 PRSS2 PRND F2	7.05e-05	56	175	5	CID000162656
Drug	abrine	PRSS2 STAB2 KALRN ADAM21 LAMA3 CR2 FCGBP NKX2-1 PKHD1 KLKB1	7.52e-05	285	175	10	ctd:C496492
Drug	polybrene	PRSS1 PRSS2 F2 LTK KLKB1	7.68e-05	57	175	5	CID000024769
Drug	glycine methyl ester	NPC1 BOC PRND OCA2	7.91e-05	30	175	4	CID000069221
Drug	N-benzoyl-L-arginine	PRSS1 PRSS2 KLK6 F2 KLKB1	8.35e-05	58	175	5	CID000097369
Drug	Patamostat	PRSS1 PRSS2 F2	9.33e-05	12	175	3	CID000065921
Drug	Chromozym Pk	PRSS1 PRSS2 KLKB1	9.33e-05	12	175	3	CID003080855
Drug	5-amidinoindole	PRSS1 PRSS2 F2	9.33e-05	12	175	3	CID000122670
Drug	4-amidinophenylpyruvic acid	PRSS1 PRSS2 F2	9.33e-05	12	175	3	CID000151496
Drug	Rgd Peptide	COL3A1 BOC COL6A3 ITGA11 SPEG LAMA3 F2 PIK3R4 NID1	1.01e-04	239	175	9	CID000104802
Drug	Gly-pro-arg	PRSS1 PRSS2 F2 PIK3R4	1.02e-04	32	175	4	CID000170776
Drug	foscarnet	COL3A1 COL6A3 ADAM21 POLRMT PFAS OS9 COL14A1 BSN	1.15e-04	190	175	8	CID000003414
Drug	AC1LAKND	COL3A1 BOC COL6A3 LAMP2 COL14A1	1.15e-04	62	175	5	CID000470146
Drug	fenpropathrin	PRSS1 PRSS2 F2 PKHD1 KLKB1	1.15e-04	62	175	5	CID000047326
Drug	ps x	OCA2 USP6 NID1	1.21e-04	13	175	3	CID009549234
Drug	4-chloro-3-ethoxy-7-guanidinoisocoumarin	PRSS1 PRSS2 KLKB1	1.21e-04	13	175	3	CID000196678
Drug	PAMBA	BOC F2 LPA	1.21e-04	13	175	3	CID000065526
Drug	Pd-Ti	PRSS1 PRSS2 CNTN5	1.21e-04	13	175	3	CID006452040
Drug	Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A	HGFAC DMXL2 ETV5 OAS3 OCA2 NLGN1 KLHL25 COL14A1	1.28e-04	193	175	8	2275_UP
Drug	benzamidine	HGFAC PRSS1 PRSS2 KLK6 F2 TYR KLKB1	1.45e-04	147	175	7	CID000002332
Drug	haloperidol; Up 200; 10uM; PC3; HT_HG-U133A	KIAA0232 CRMP1 NFATC3 TLN2 CHPF2 KAZALD1 PCOLCE MYBPC3	1.48e-04	197	175	8	1244_UP
Drug	sulfate	BOC HGFAC PRSS1 COL6A3 PRSS2 MRI1 TBL1Y ENPP3 ITGA10 LAMA3 OCA2 F2 ARF5 TYR IGF2R FIG4 LPA ENTPD2 NID1 CHPF2 SIGLEC1 MUC5AC KLKB1	1.50e-04	1292	175	23	CID000001117
Drug	Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	LAMA3 CMAS PTPRA TMPRSS3 MACF1 TLN2 HSPA2 GAREM1	1.53e-04	198	175	8	5532_DN
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	NPC1 ZNF93 MAP4K3 LAMA3 PFAS LANCL2 CRY1 CHPF2	1.53e-04	198	175	8	6242_DN
Drug	Pizotifen malate [5189-11-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A	ZNF93 COL6A3 KIAA0232 SPEG ETV5 OSMR ALDOB MYBPC3	1.53e-04	198	175	8	5491_UP
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	COL3A1 ZNF93 STAB2 SPEG OCA2 PTPRA SIGLEC1 TOP3B	1.53e-04	198	175	8	7224_UP
Drug	Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	ZNF93 FSCN3 OCA2 PTPRA CNTN5 COL14A1 LTK MUC5AC	1.58e-04	199	175	8	7234_UP
Drug	Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A	IL12B STAB2 FSCN3 OBSL1 PAQR6 STRN SIGLEC1 PCOLCE	1.58e-04	199	175	8	5094_UP
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A	KALRN FSCN3 ETV5 OCA2 CUBN TENM3 ALDOB MUC5AC	1.58e-04	199	175	8	3546_UP
Drug	S-2238	PRSS1 PRSS2 F2 KLKB1	1.64e-04	36	175	4	CID000123853
Disease	thrombin measurement	TTF2 F2 KLKB1	1.03e-05	8	170	3	EFO_0020768
Disease	total lipids in VLDL measurement	HGFAC IGF2R CELSR2 LPA LPAL2	2.53e-05	60	170	5	EFO_0022314
Disease	cholesterol in very large VLDL measurement	HGFAC IGF2R CELSR2 LPA LPAL2	3.74e-05	65	170	5	EFO_0022230
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	HGFAC CRY1 IGF2R CELSR2 LPA MACF1 LPAL2 MAP4K2	4.97e-05	224	170	8	EFO_0004530, EFO_0008317
Disease	free cholesterol to total lipids in large LDL percentage	HGFAC CELSR2 LPA MACF1 LPAL2	6.99e-05	74	170	5	EFO_0022280
Disease	neuroligin-1 measurement	STAB2 NLGN1	9.86e-05	3	170	2	EFO_0802802
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	CELSR2 LPA LPAL2	1.20e-04	17	170	3	EFO_0022232
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	HGFAC ADAM21 TBC1D5 IGF2R CELSR2 LPA	1.48e-04	137	170	6	EFO_0004611, EFO_0008591
Disease	Alzheimer disease, dementia, family history of Alzheimer’s disease	ITGA11 KCNH8 DCBLD1 TREM2	1.70e-04	48	170	4	EFO_0009268, MONDO_0001627, MONDO_0004975
Disease	prothrombin measurement	TTF2 F2	1.96e-04	4	170	2	EFO_0020692
Disease	C-reactive protein measurement	AKAP6 NPC1 HGFAC DMXL2 KCP NLGN1 ZNF112 METAP1 STRN TRANK1 CELSR2 LPA TREM2 MACF1 NID1 SCAF11 BSN MYBPC3	2.19e-04	1206	170	18	EFO_0004458
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	CELSR2 LPA LPAL2	2.32e-04	21	170	3	EFO_0022246
Disease	phospholipids in medium VLDL measurement	HGFAC IGF2R CELSR2 LPA	2.32e-04	52	170	4	EFO_0022154
Disease	interleukin 1 receptor antagonist measurement	AKAP6 OCA2 TRANK1 MEGF11	2.50e-04	53	170	4	EFO_0004754
Disease	free cholesterol to total lipids in small LDL percentage	ZNF229 CELSR2 LPA LPAL2	2.50e-04	53	170	4	EFO_0022286
Disease	obesity (implicated_via_orthology)	MKKS NT5DC4 TBC1D5 ETV5 SIM1 F2 JUP	2.61e-04	215	170	7	DOID:9970 (implicated_via_orthology)
Disease	total lipids in medium VLDL	HGFAC IGF2R CELSR2 LPA	2.69e-04	54	170	4	EFO_0022153
Disease	triglycerides in medium VLDL measurement	HGFAC CELSR2 LPA LPAL2	2.88e-04	55	170	4	EFO_0022155
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	HGFAC CRYBA2 IGF2R CELSR2 LPA MACF1 LPAL2 MYBPC3	3.00e-04	291	170	8	EFO_0008317, EFO_0020946
Disease	triglycerides in LDL measurement	HGFAC IGF2R CELSR2 LPA	3.09e-04	56	170	4	EFO_0022320
Disease	free cholesterol to total lipids in large HDL percentage	HGFAC CELSR2 LPA LPAL2	3.09e-04	56	170	4	EFO_0022279
Disease	PANCREATITIS, HEREDITARY	PRSS1 PRSS2	3.26e-04	5	170	2	167800
Disease	oculocutaneous albinism (implicated_via_orthology)	OCA2 TYR	3.26e-04	5	170	2	DOID:0050632 (implicated_via_orthology)
Disease	Hereditary pancreatitis	PRSS1 PRSS2	3.26e-04	5	170	2	cv:C0238339
Disease	Autosomal Dominant Hereditary Pancreatitis	PRSS1 PRSS2	3.26e-04	5	170	2	C4080064
Disease	Liver Cirrhosis	NPC1 COL3A1 F2 SLC30A10 PCOLCE	3.32e-04	103	170	5	C0023890
Disease	phospholipids:total lipids ratio	HGFAC IGF2R CELSR2 LPA MACF1 LPAL2 MYBPC3	3.62e-04	227	170	7	EFO_0020946
Disease	Fibrosis, Liver	NPC1 COL3A1 F2 SLC30A10 PCOLCE	3.63e-04	105	170	5	C0239946
Disease	phospholipids in VLDL measurement	HGFAC IGF2R CELSR2 LPA	3.78e-04	59	170	4	EFO_0022301
Disease	cholesterol to total lipids in IDL percentage	ZNF229 LPA MACF1 LPAL2	4.03e-04	60	170	4	EFO_0022233
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	HGFAC IGF2R CELSR2 LPA LPAL2 MAP4K2	4.15e-04	166	170	6	EFO_0004530, EFO_0004611
Disease	free cholesterol in VLDL measurement	HGFAC IGF2R CELSR2 LPA	4.30e-04	61	170	4	EFO_0022276
Disease	digestive system infectious disorder	NPC1 FLNB CNTN5	4.43e-04	26	170	3	MONDO_0043424
Disease	triglycerides in medium LDL measurement	HGFAC IGF2R CELSR2 LPA	4.57e-04	62	170	4	EFO_0022322
Disease	free cholesterol in very large HDL measurement	HGFAC CELSR2 LPA LPAL2	4.57e-04	62	170	4	EFO_0022273
Disease	trefoil factor 1 measurement	TMPRSS3 MUC5AC	4.88e-04	6	170	2	EFO_0021865
Disease	Malignant neoplasm of breast	AKAP6 BOC FLNB KALRN OBSCN OCA2 SIM1 CUBN PIK3R4 FCRL3 BRCA1 MACF1 HADHB FCRL5 GEN1 PCDH8	5.06e-04	1074	170	16	C0006142
Disease	triglycerides in small LDL measurement	HGFAC CELSR2 LPA LPAL2	5.48e-04	65	170	4	EFO_0022323
Disease	cholesterol in large VLDL measurement	HGFAC IGF2R CELSR2 LPA	5.48e-04	65	170	4	EFO_0021902
Disease	total lipids in very large HDL measurement	HGFAC CELSR2 LPA LPAL2	5.80e-04	66	170	4	EFO_0022312
Disease	total lipids in large VLDL	HGFAC CELSR2 LPA LPAL2	6.14e-04	67	170	4	EFO_0022175
Disease	cholesterol to total lipids in very small VLDL percentage	ZNF229 CELSR2 LPA LPAL2	6.14e-04	67	170	4	EFO_0022245
Disease	longevity, healthspan, parental longevity	TYR CELSR2 LPA	6.15e-04	29	170	3	EFO_0004300, EFO_0007796, EFO_0009762
Disease	free cholesterol in large VLDL measurement	HGFAC CELSR2 LPA LPAL2	6.50e-04	68	170	4	EFO_0022265
Disease	creatinine measurement	HGFAC BCAS3 SPEG OBSCN ETV5 CELA2B SIM1 CUBN CRMP1 IGF2R CELSR2 LPA PKHD1 BSN ALDOB	6.73e-04	995	170	15	EFO_0004518
Disease	Hereditary pancreatitis	PRSS1 PRSS2	6.80e-04	7	170	2	C0238339
Disease	fructosamine measurement	CNTN5 MAP4K2	6.80e-04	7	170	2	EFO_0009303
Disease	Albinism, Oculocutaneous	OCA2 TYR	6.80e-04	7	170	2	C0078918
Disease	Oculocutaneous albinism	OCA2 TYR	6.80e-04	7	170	2	cv:C0078918
Disease	lipoprotein A measurement, apolipoprotein A 1 measurement	LPA LPAL2	6.80e-04	7	170	2	EFO_0004614, EFO_0006925
Disease	triglycerides to total lipids in very small VLDL percentage	HGFAC CELSR2 LPA LPAL2	6.87e-04	69	170	4	EFO_0022341
Disease	cholesterol in very large HDL measurement	HGFAC CELSR2 LPA LPAL2	6.87e-04	69	170	4	EFO_0022229
Disease	lipid measurement, high density lipoprotein cholesterol measurement	HGFAC OBSL1 ETV5 COLQ METAP1 CELSR2 LPA LPAL2	6.87e-04	330	170	8	EFO_0004529, EFO_0004612
Disease	cholesteryl esters to total lipids in large LDL percentage	HGFAC CELSR2 LPA	7.50e-04	31	170	3	EFO_0022249
Disease	cholesteryl esters to total lipids in very small VLDL percentage	HGFAC ZNF229 LPA LPAL2	7.65e-04	71	170	4	EFO_0022259
Disease	intraocular pressure measurement	TTF2 COL6A3 KALRN BCAS3 F2 TYR PKHD1 KAZALD1 SLC30A10 MYBPC3	7.77e-04	509	170	10	EFO_0004695
Disease	Liver diseases	NPC1 COL3A1 GPT JUP	8.06e-04	72	170	4	C0023895
Disease	Liver Dysfunction	NPC1 COL3A1 GPT JUP	8.06e-04	72	170	4	C0086565
Disease	argininate measurement	CELA2B IGF2R	9.03e-04	8	170	2	EFO_0800055
Disease	heart failure, body fat percentage	NPC1 LPA	9.03e-04	8	170	2	EFO_0003144, EFO_0007800
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	CELSR2 LPA LPAL2	9.86e-04	34	170	3	EFO_0008317, EFO_0008596, EFO_0020944
Disease	chylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	CELSR2 LPA LPAL2	9.86e-04	34	170	3	EFO_0008317, EFO_0008596, EFO_0020947
Disease	myocardial infarction	COL6A3 KALRN BCAS3 DCBLD1 OAS3 CELSR2 TENM3 LPA	1.00e-03	350	170	8	EFO_0000612
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	HGFAC IGF2R LPA LPAL2	1.09e-03	78	170	4	EFO_0022187
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	HGFAC CRYBA2 IGF2R CELSR2 LPA LPAL2 MAP4K2	1.10e-03	274	170	7	EFO_0004530, EFO_0004612
Disease	plasma renin activity measurement	TENM3 KLKB1	1.16e-03	9	170	2	EFO_0006828
Disease	Pancreatitis, Chronic	PRSS1 PRSS2	1.16e-03	9	170	2	C0149521
Disease	familial Mediterranean fever (is_marker_for)	F2 LPA	1.16e-03	9	170	2	DOID:2987 (is_marker_for)
Disease	Endomyocardial Fibrosis	COL3A1 IGF2R	1.16e-03	9	170	2	C0553980
Disease	cholesteryl esters to total lipids in medium LDL percentage	HGFAC IGF2R LPA	1.26e-03	37	170	3	EFO_0022252
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	HGFAC CRYBA2 IGF2R LPA LPAL2 MAP4K2	1.28e-03	206	170	6	EFO_0004612, EFO_0020947
Disease	apolipoprotein A 1 measurement	NPC1 HGFAC ITGA10 METAP1 TRANK1 CELSR2 NFATC3 LPA MACF1 LPAL2 ALDOB SLC30A10 MYBPC3	1.32e-03	848	170	13	EFO_0004614
Disease	snoring measurement	SIM1 TYR MACF1 ATP1B2	1.43e-03	84	170	4	EFO_0008341
Disease	hair colour measurement, eye colour measurement, skin pigmentation measurement	OCA2 TYR	1.44e-03	10	170	2	EFO_0007009, EFO_0007822, EFO_0009764
Disease	aspirin use measurement	CELSR2 LPA LPAL2	1.47e-03	39	170	3	EFO_0007013
Disease	platelet component distribution width	NPC1 COL3A1 KALRN KIAA0232 TBC1D5 ETV5 CUBN FAM187B TRANK1 CNTN5 MACF1 SIGLEC1	1.50e-03	755	170	12	EFO_0007984
Disease	ciliopathy (implicated_via_orthology)	MKKS MAP4K3 MAP4K2	1.59e-03	40	170	3	DOID:0060340 (implicated_via_orthology)
Disease	apolipoprotein B measurement	HGFAC ZNF112 SIM1 ZNF229 IGF2R SGMS1 CELSR2 FIG4 LPA LPAL2 KLKB1	1.68e-03	663	170	11	EFO_0004615
Disease	Fatty Liver	COL3A1 GPT F2 HADHB	1.70e-03	88	170	4	C0015695
Disease	Steatohepatitis	COL3A1 GPT F2 HADHB	1.70e-03	88	170	4	C2711227
Disease	venous thromboembolism, response to antineoplastic agent	KALRN CNTN5 PKHD1	1.71e-03	41	170	3	EFO_0004286, GO_0097327
Disease	pigmentation disease (is_implicated_in)	OCA2 TYR	1.75e-03	11	170	2	DOID:10123 (is_implicated_in)
Disease	venous thromboembolism, von Willebrand factor measurement	TTF2 STAB2 F2	1.83e-03	42	170	3	EFO_0004286, EFO_0004629
Disease	aortic stenosis, aortic valve calcification	FLNB LPA TREM2	1.83e-03	42	170	3	EFO_0000266, EFO_0005239
Disease	cholesteryl esters to total lipids in small LDL percentage	HGFAC LPA LPAL2	1.83e-03	42	170	3	EFO_0022255
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	HGFAC IGF2R CELSR2 LPA MACF1 LPAL2	1.87e-03	222	170	6	EFO_0008317, EFO_0020943
Disease	sleep duration, low density lipoprotein cholesterol measurement	BOC IGF2R CELSR2 LPA	1.93e-03	91	170	4	EFO_0004611, EFO_0005271
Disease	HbA1c measurement	PFAS NLGN1 CR2 JUP FIG4 CNTN5 MACF1 BSN ATP1B2 MAP4K2 MYBPC3	1.93e-03	675	170	11	EFO_0004541
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	HGFAC METAP1 IGF2R CELSR2 LPA LPAL2	1.95e-03	224	170	6	EFO_0004574, EFO_0008317
Disease	cholesteryl esters to total lipids in small HDL percentage	CELSR2 LPA LPAL2	1.96e-03	43	170	3	EFO_0022254
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	HGFAC IGF2R CELSR2 LPA LPAL2	1.97e-03	153	170	5	EFO_0004611, EFO_0020944
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	HGFAC TBC1D5 IGF2R CELSR2 LPA LPAL2	2.00e-03	225	170	6	EFO_0008317, EFO_0010351
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	HGFAC IGF2R CELSR2 LPA MACF1 LPAL2	2.00e-03	225	170	6	EFO_0008317, EFO_0020947
Disease	Thromboembolism	F2 LPA	2.10e-03	12	170	2	C0040038
Disease	cholesterol to total lipids in large VLDL percentage	CELSR2 LPA LPAL2	2.23e-03	45	170	3	EFO_0022236
Disease	aspartate aminotransferase measurement	ENTPD7 HGFAC FLNB KALRN TBC1D5 OBSCN CUBN METAP1 KLHL25 HMCN2 BRCA1 SLC30A10 MYBPC3	2.32e-03	904	170	13	EFO_0004736
Disease	alkaline phosphatase measurement	ENPP3 FBXW4 KCP FAM43B CRMP1 METAP1 TRANK1 NFATC3 MACF1 CHPF2 ALDOB MAP4K2 KLHL17 MYBPC3	2.32e-03	1015	170	14	EFO_0004533
Disease	parental longevity	NLGN1 COLQ ANKRD27 TYR IGF2R CELSR2 LPA BSN LPAL2	2.36e-03	494	170	9	EFO_0007796
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	CELSR2 LPA LPAL2	2.38e-03	46	170	3	EFO_0008317, EFO_0008596, EFO_0020943
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	HGFAC SIM1 CELSR2 LPA	2.62e-03	99	170	4	EFO_0004611, EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
EGSSGHSAALQVPCY	ALX4	141	Q9H161
ILQACGGHSLGAYSV	GPT	111	P24298
QGNRFGHCGINGTTY	ADAM21	536	Q9UKJ8
CQAAKGQYVHTGSSG	ALDOB	336	P05062
QATCATQGTGLYDGL	ARF5	156	P84085
CATGNAEYQHSKGSG	EVX1	131	P49640
SGEFCTYGELGTQAH	CRYBA2	171	P53672
LESGAAYNCSLHGAS	ASB6	281	Q9NWX5
YCSLHGAQGGGLASV	DMXL2	2161	Q8TDJ6
GSVLGNYSCAAQGTQ	CELSR2	1496	Q9HCU4
QSLLTGYQCSGNDEH	DTL	26	Q9NZJ0
HQSRGGACGDNIQSY	BCAS3	251	Q9H6U6
GACGAYTTAILQHQA	CELF6	241	Q96J87
QYGLVAACAAGGQGH	HADHB	451	P55084
KDSGHYQCLATNTVG	CNTN5	166	O94779
AVGVIEGNYSCLAHG	IGDCC4	111	Q8TDY8
PQLSHSAVGGYCNGN	NKX2-1	76	P43699
INGTCFYTKNGHSLG	RANBP10	176	Q6VN20
VVCAGIAEQHGYGFS	OCA2	791	Q04671
YNQAASDSGSCGHVP	OSMR	861	Q99650
YSGRATSGTEHQFCG	PCOLCE	146	Q15113
GGCHSPGDSQYQELA	GOLGA6A	61	Q9NYA3
EYENGGHCLGSTALT	NIBAN3	136	Q86XR2
EFCGGGSLQEIYHAT	MAP4K2	91	Q12851
DNNGNTPLHLACTYG	ANKRD27	526	Q96NW4
GVILADQGTYGCESH	OBSL1	1511	O75147
DYTADQHGTCGDGLL	COLQ	366	Q9Y215
GGSQSCSNGQHEYGS	FLG2	386	Q5D862
LSQSSGFEQHVCGSG	FLG2	436	Q5D862
EFCGGGSLQDIYHVT	MAP4K3	91	Q8IVH8
SVVQEGCGHNSSYIQ	MEGF11	996	A6BM72
VCGGQDFYSHSNTLA	KLHL33	276	A6NCF5
LHNGFGGYVCTTSQS	MKKS	46	Q9NPJ1
QSPLCGSDGHTYSQI	KAZALD1	131	Q96I82
QANGFSVVRSYCGHG	METAP1	281	P53582
ASLNTQGIYAGGGVC	LAMA3	376	Q16787
NLNYGLVVDCGSSGS	ENTPD7	81	Q9NQZ7
FYIANSEGLSSNCHG	ITIH5	826	Q86UX2
CTGSSSNIGAGYVVH	IGLV1-50	41	A0A075B6I6
CGATSAAYAGGEGLQ	GARIN4	231	Q8IYT1
AQVQVGDSGHYECTA	HMCN2	1131	Q8NDA2
DAGTYDCVAHNLLGS	HMCN2	4366	Q8NDA2
QLGNCSGIGDSTHYG	ATP1B2	156	P14415
YLGNAVTLHAKGDGC	FAM43B	76	Q6ZT52
GCGSSSYTVTPHLNG	GPR137C	386	Q8N3F9
ICHGTAGNGYSFLSL	LANCL2	366	Q9NS86
LNSTGSYGHELDLGQ	BSN	936	Q9UPA5
QHSSCDVPGGGISSY	ENTPD2	71	Q9Y5L3
SGRHGPTQTQCDGAY	LTK	76	P29376
DDHKNGSCGVSYIAQ	FLNB	2241	O75369
DLGTTYSCVGVFQHG	HSPA2	11	P54652
LHSDYCSQNTCLNGG	FAT2	3946	Q9NYQ8
AEHSGNYSCEANNGL	FCRL5	626	Q96RD9
CNESPHGDGYSSGVI	KIAA0232	811	Q92628
SGANGQVRCALYGHE	PCDH8	421	O95206
TAQHYGIAGCGTLLI	PEX7	36	O00628
YGITTALSQCPQGHN	NID1	1196	P14543
RGQSLGSLYTHLQGC	EVPL	221	Q92817
LSVCVYGNNLHGNSE	GAREM1	386	Q9H706
QDSGIYTCIATNDHG	KALRN	2541	O60229
DCYTFGSNQHGQLGT	NEK8	581	Q86SG6
ISDHGTVTYNGSICG	LAMP2	66	P13473
FSGQAVQCQSYGGVS	LORICRIN	151	P23490
SCSHEQALGANYGEK	ETV5	101	P41161
EYTLVQNHCGGKDST	MUC5AC	926	P98088
ELATGLQYFGCSIHG	ITGA11	596	Q9UKX5
GAGGSCVNLLTLSHY	NLGN1	301	Q8N2Q7
SYICGFLNASIHTGN	OR5B12	146	Q96R08
LASAPVSGAGNHSYC	PIK3IP1	56	Q96FE7
GHGCGQEALSTSHGY	PAQR6	211	Q6TCH4
NLSGCYNLTDNGLGH	FBXL14	96	Q8N1E6
SGDISHSQGTNGTCY	GPR42	156	O15529
NGGSCSNTQDPQSYH	HGFAC	171	Q04756
GQYTCHKGGEVLSHS	IL12B	86	P29460
TYDSGIHSGANTCVP	JUP	21	P14923
NTGSCLQQEGYEHRG	KLHL4	31	Q9C0H6
VGSSVGSVNGYHTCK	MACF1	4416	Q9UPN3
CGKGGHAAYSSAVNI	NPC1	1011	O15118
TAEDQGEYHCGLAQG	OBSCN	4686	Q5VST9
GTSTGPHQHCAVYSG	NT5DC4	281	Q86YG4
HDQGQYECQAVSSLG	PXDNL	481	A1KZ92
YQGSSVSNLHVEPCG	BRCA1	261	P38398
GNATGHLVGRYCGNS	CUBN	1801	O60494
ACGGNVYIHDADSAG	CUBN	2216	O60494
HTSGNILGRYCGNTI	CUBN	2401	O60494
GTDGHTYANVCALQA	HTRA3	91	P83110
TAAVLTNGLYCFHQG	HIGD2B	56	Q4VC39
VVGGAQAGDAGTYHC	IGSF8	256	Q969P0
ALYVAGGNDGTSCLN	KLHL17	531	Q6TDP4
HGSAELENCLYVVGG	KLHL25	381	Q9H0H3
CHALASGNKLYVVGG	KLHL25	531	Q9H0H3
YLSGISGRACANGIH	BOC	921	Q9BWV1
VNTSCQDGYQLTGHA	CR2	681	P20023
VHGIGSLTSVLGCNY	CELA2B	231	P08218
NVSGNTHLCISNGNY	GFRA1	406	P56159
RSKSNTNCGGGNHGY	ENPP3	471	O14638
IHAYVSACQAAGGQV	FCGBP	2706	Q9Y6R7
GGGNLSILCSNIHAY	FCGBP	3896	Q9Y6R7
DHGDTLSLQYGGSQL	FIG4	536	Q92562
QESTVGGGTTRHCFY	COL14A1	961	Q05707
LCNHDVVLGNESTYG	CENPJ	806	Q9HC77
GGLLAGQTYHVAVVC	COL6A3	3046	P12111
SSGSCSQGSGILHYA	CRY1	526	Q16526
SGDISHSQGTNGTCY	FFAR3	156	O14843
GYVGSSSGHDLIQCN	FSCN3	396	Q9NQT6
QSPGVQDCYHGDGQS	LPA	1161	P08519
NYSCEADNGLGAQHS	FCRL3	541	Q96P31
YCLQTDGNHLLATGS	FBXW4	341	P57775
CAKGHLGDYQLGNSS	ITGA10	86	O75578
YLNAGGHVDGCLTND	GEN1	141	Q17RS7
TRESNPHCGSDGQTY	SPINK6	41	Q6UWN8
GSSGYSLRLCNTGDN	KLKB1	366	P03952
EAVEGGCSHLGQSYA	COL3A1	26	P02461
SGNDILLYCNSSGAH	FAM187B	36	Q17R55
EHSGNYSCEANNGLG	FCRL2	361	Q96LA5
ELGDGCGHLVTYQDS	DCBLD1	36	Q8N8Z6
GTSCKGYALAHTQEG	SCAF11	281	Q99590
QDGSCNGLQHYAALG	POLRMT	921	O00411
LQVTGSGHCPYSTAQ	CRMP1	326	Q14194
SSYGSICHNGGKCVE	CNTNAP5	961	Q8WYK1
QLSGHLNYTCGAENS	DRD3	6	P35462
NPQYAGAIVVHCSAG	PTPRA	431	P18433
LECQSYGNGAHLASI	REG4	56	Q9BYZ8
VYSTLLNSGCQGGEH	OAS3	166	Q9Y6K5
NIQLSYSDGDDCGHG	IGF2R	561	P11717
SNGEQCYSGGTDGLI	STRN	526	O43815
GSEHNLAIIGGVCYS	SERGEF	341	Q9UGK8
PYQVSLNSGSHFCGG	PRSS3P2	36	Q8NHM4
HCISENEGGAHGYVN	TMEM121B	556	Q9BXQ6
TGPSVQECYHSNGQS	LPAL2	21	Q16609
CTGSSSNIGAGYDVH	IGLV1-40	41	P01703
NIDGCLTNGHIYVSG	CMAS	281	Q8NFW8
LQGVRESDGGNYTCS	JAML	221	Q86YT9
ESDGGNYTCSIHLGN	JAML	226	Q86YT9
QGCRYHGVTTASGET	KCP	841	Q6ZWJ8
NVNYGIVVDCGSSGS	ENTPD4	86	Q9Y227
TIRNYSLGCNGSHFD	SIM1	726	P81133
THCNTGALATAGYGT	MRI1	166	Q9BV20
GTLQCHVEGDYIGSQ	PKHD1	211	P08F94
GSGGVYALCSAHLAN	RHBDL1	311	O75783
HSQTYGNGSKCDLNG	OS9	171	Q13438
AASQSYECLHKVGNG	AKAP6	451	Q13023
QATCATQGTGLYEGL	ARF4	156	P18085
SLGVGCVSQHQGQQY	CHPF2	266	Q9P2E5
CQGSHYLAIASDNGA	PIK3R4	1051	Q99570
QASLQFQGYHLCGGS	TMPRSS3	231	P57727
VCNAPHSYNGAILSG	TMPRSS11D	336	O60235
HSYNGAILSGMLCAG	TMPRSS11D	341	O60235
GLNGACSVHEYTGTF	TOP3B	31	O95985
NGCAEHNGGPSLDTY	SLC30A10	426	Q6XR72
ECGQAFAQYSGLSIH	ZNF561	341	Q8N587
HTGGYNGLNQCSTTT	ZNF93	126	P35789
STSCGAQLNHSSYGN	USPL1	856	Q5W0Q7
STGAQDGGVYTCTAQ	SPEG	1546	Q15772
DGGVYTCTAQNLAGE	SPEG	1551	Q15772
HAGLYECSATNVLGS	SPEG	2651	Q15772
LYHSAGNIIGVGQCL	SLC27A1	291	Q6PCB7
GGNYHSSLGTRCELS	SRPX2	76	O60687
QHGYLTCTSAGDNYG	SRPX2	271	O60687
SLGVYGFGCEDSLNH	SF3B1	1196	O75533
PDGIHYNGCSEANVT	PRND	86	Q9UKY0
AHVVAGTAGYCFGNL	PFAS	341	O15067
THAGSHGVYESICNG	UGT1A1	371	P22309
LGPCSDGHYQSASGQ	TTC5	301	Q8N0Z6
EYNSHQSLCNGTPEG	TYR	281	P14679
HIEKYSINSCSVNGG	NFATC3	601	Q12968
GGLSITGSHNMCGDY	SGMS1	266	Q86VZ5
ASQNCGSGVVGIVDY	STAB2	2261	Q8WWQ8
QCSGHGTYLQESGSC	TENM3	651	Q9P273
GAYHCQAQAPGSATT	SIGLEC1	956	Q9BZZ2
HELGNCLGGTSVGYA	TMEM168	401	Q9H0V1
LNSGYHFCGGSLISE	PRSS2	41	P07478
TNITVNEDLGYCSGG	VN1R4	156	Q7Z5H5
LVHSYQGTGGIFEVC	TBL1Y	486	Q9BQ87
GLYQCQSLHGSEADT	TREM2	106	Q9NZC2
CGKGFSYTSGLRNHQ	ZNF229	801	Q9UJW7
CGKGFSRNSYLQGHQ	ZNF112	586	Q9UJU3
QLLTCAAQGNEHYTG	TLN2	1106	Q9Y4G6
GNCAEGLGTNYRGHV	F2	106	P00734
ADNHYCSSGQGQGRG	TBC1D5	671	Q92609
LNSGYHFCGGSLINE	PRSS1	41	P07477
GIYGTEGRECLQNSH	WNT8A	266	Q9H1J5
CYQTGQLSGIAEAHF	TRANK1	1976	O15050
LGCGQTDRQGQSSHY	RPTN	281	Q6XPR3
CGDGYSNGQLGNHSE	USP6	1281	P35125
AGGSSQCYRGHTNQD	TTF2	516	Q9UNY4
QAALYTSGHLLCGGV	KLK6	36	Q92876
HLQTGGAAYTQAQLC	KCNH8	936	Q96L42
TGAGDAGGYTCIATN	LRFN4	341	Q6PJG9
DAGHYALCTSGGQAL	MYBPC3	521	Q14896