Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase I

BAZ1B UBTF

1.40e-0437102GO:0045943
GeneOntologyBiologicalProcessregulation of transcription by RNA polymerase I

BAZ1B UBTF

2.56e-0450102GO:0006356
GeneOntologyBiologicalProcesstranscription by RNA polymerase I

BAZ1B UBTF

6.39e-0479102GO:0006360
DomainHMG_box_2

HMGXB3 HMGB3 UBTF

9.27e-099103PF09011
DomainHMG_box

HMGXB3 HMGB3 UBTF

2.55e-0653103PF00505
DomainHMG

HMGXB3 HMGB3 UBTF

2.70e-0654103SM00398
DomainHMG_BOX_2

HMGXB3 HMGB3 UBTF

2.70e-0654103PS50118
Domain-

HMGXB3 HMGB3 UBTF

2.86e-06551031.10.30.10
DomainHMG_box_dom

HMGXB3 HMGB3 UBTF

4.74e-0665103IPR009071
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

BAZ1B TADA3 UBTF

3.03e-0425483M27131
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

AHNAK IRS4 BAZ1B TADA3 RBM28 HMGB3 UBTF

1.28e-0995410736373674
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

AHNAK IRS4 BAZ1B RBM28 UBTF

5.36e-0765310522586326
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HMGXB3 BAZ1B HIVEP2 HMGB3 UBTF

8.04e-0770910522988430
Pubmed

Human transcription factor protein interaction networks.

IRS4 BAZ1B TADA3 RBM28 HMGB3 UBTF

8.67e-07142910635140242
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

IRS4 BAZ1B RBM28 UBTF

1.60e-0633010433301849
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

AHNAK BAZ1B RBM28

4.49e-0611810337105989
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

AHNAK BAZ1B TADA3 HMGB3 UBTF

4.65e-06101410532416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

AHNAK IRS4 BAZ1B RBM28 UBTF

4.88e-06102410524711643
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

AHNAK BAZ1B TADA3 RBM28 UBTF

1.52e-05129410530804502
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

AHNAK BAZ1B RBM28 UBTF

1.71e-0560110433658012
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

IRS4 BAZ1B RBM28 UBTF

2.20e-0564110436057605
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

BAZ1B RBM28 UBTF

3.23e-0522810330471916
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

AHNAK IRS4 HMGB3

3.85e-0524210334011540
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

AHNAK RBM28 UBTF

4.00e-0524510321182205
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

AHNAK RBM28 UBTF

5.22e-0526810333024031
Pubmed

Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action.

AHNAK RBM28

6.07e-054110219805454
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

IRS4 BAZ1B HIVEP2

8.99e-0532210326514267
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

AHNAK IRS4 BAZ1B UBTF

9.54e-0593410433916271
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

HMGXB3 AHNAK BAZ1B

9.84e-0533210337433992
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

BAZ1B RBM28 UBTF

9.84e-0533210325693804
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

IRS4 TADA3 UBTF

1.05e-0433910330415952
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

AHNAK BAZ1B UBTF

1.06e-0434010329478914
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

AHNAK IRS4

1.06e-045410225631074
Pubmed

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

BAZ1B UBTF

1.18e-045710221555454
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

AHNAK BAZ1B RBM28 UBTF

1.19e-0498910436424410
Pubmed

Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA.

AHNAK RBM28

1.53e-046510234645483
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HMGXB3 BAZ1B RBM28 UBTF

1.70e-04108410411544199
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TADA3 RBM28 HMGB3 UBTF

1.81e-04110310434189442
Pubmed

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.

BAZ1B RBM28

1.88e-047210233106477
Pubmed

Nucleolar proteome dynamics.

BAZ1B RBM28 UBTF

1.96e-0441910315635413
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

BAZ1B RBM28 UBTF

2.11e-0443010338172120
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

IRS4 RBM28 UBTF

2.26e-0444010334244565
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

AHNAK BAZ1B

2.68e-048610237253089
InteractionSMC5 interactions

AHNAK IRS4 BAZ1B TADA3 RBM28 HMGB3 UBTF

7.63e-081000107int:SMC5
InteractionKLF8 interactions

IRS4 BAZ1B TADA3 RBM28 UBTF

2.65e-07329105int:KLF8
InteractionDNAJC9 interactions

BAZ1B TADA3 RBM28 UBTF

8.93e-06296104int:DNAJC9
InteractionCGAS interactions

BAZ1B RBM28 HMGB3 UBTF

1.36e-05329104int:CGAS
InteractionSIRT7 interactions

AHNAK IRS4 BAZ1B RBM28 UBTF

1.46e-05744105int:SIRT7
InteractionMYCN interactions

IRS4 BAZ1B TADA3 RBM28 HMGB3 UBTF

1.64e-051373106int:MYCN
InteractionH3C1 interactions

AHNAK BAZ1B RBM28 HMGB3 UBTF

3.69e-05901105int:H3C1
InteractionKLF16 interactions

IRS4 BAZ1B RBM28 UBTF

3.70e-05425104int:KLF16
InteractionZNF330 interactions

BAZ1B RBM28 HMGB3 UBTF

4.47e-05446104int:ZNF330
InteractionZBTB2 interactions

IRS4 BAZ1B RBM28 UBTF

4.63e-05450104int:ZBTB2
InteractionMTNR1A interactions

IRS4 BAZ1B HIVEP2

6.31e-05166103int:MTNR1A
InteractionLHX2 interactions

BAZ1B RBM28 HMGB3

8.43e-05183103int:LHX2
InteractionUTP23 interactions

BAZ1B RBM28 UBTF

9.58e-05191103int:UTP23
InteractionH2BC8 interactions

BAZ1B TADA3 HMGB3 UBTF

1.21e-04576104int:H2BC8
InteractionCBX3 interactions

BAZ1B TADA3 HMGB3 UBTF

1.88e-04646104int:CBX3
InteractionPOLD1 interactions

AHNAK BAZ1B RBM28

5.10e-04337103int:POLD1
InteractionRHBDD1 interactions

AHNAK IRS4 BAZ1B

5.50e-04346103int:RHBDD1
InteractionDAXX interactions

BAZ1B RBM28 UBTF

5.84e-04353103int:DAXX
InteractionFBXO43 interactions

AHNAK RBM28

5.87e-0474102int:FBXO43
InteractionAXL interactions

AHNAK BAZ1B RBM28

6.64e-04369103int:AXL
InteractionOBSL1 interactions

AHNAK BAZ1B RBM28 UBTF

6.74e-04902104int:OBSL1
InteractionLYAR interactions

BAZ1B RBM28 UBTF

6.85e-04373103int:LYAR
InteractionRFX1 interactions

HIVEP2 TADA3

7.03e-0481102int:RFX1
InteractionMEX3A interactions

HMGXB3 AHNAK BAZ1B

7.46e-04384103int:MEX3A
InteractionCHD4 interactions

AHNAK BAZ1B RBM28 UBTF

7.82e-04938104int:CHD4
InteractionDCPS interactions

AHNAK BAZ1B UBTF

8.03e-04394103int:DCPS
InteractionACTN4 interactions

AHNAK HMGB3 UBTF

8.39e-04400103int:ACTN4
InteractionTAF1B interactions

RBM28 UBTF

9.06e-0492102int:TAF1B
InteractionNAA40 interactions

AHNAK IRS4 BAZ1B UBTF

9.15e-04978104int:NAA40
InteractionKLF9 interactions

BAZ1B RBM28

9.25e-0493102int:KLF9
InteractionKAT8 interactions

BAZ1B TADA3

9.65e-0495102int:KAT8
InteractionKLF6 interactions

TADA3 RBM28

9.65e-0495102int:KLF6
InteractionKANSL1 interactions

BAZ1B TADA3

9.86e-0496102int:KANSL1
InteractionBRD2 interactions

BAZ1B TADA3 UBTF

1.03e-03429103int:BRD2
InteractionNDN interactions

AHNAK IRS4 TADA3

1.20e-03453103int:NDN
InteractionMYBBP1A interactions

BAZ1B RBM28 UBTF

1.28e-03463103int:MYBBP1A
InteractionYWHAH interactions

AHNAK IRS4 HIVEP2 HMGB3

1.43e-031102104int:YWHAH
InteractionACE2 interactions

IRS4 BAZ1B RBM28 UBTF

1.45e-031106104int:ACE2
InteractionLARP7 interactions

IRS4 RBM28 HMGB3 UBTF

1.49e-031113104int:LARP7
InteractionPOLR1G interactions

TADA3 RBM28 UBTF

1.50e-03489103int:POLR1G
InteractionTEK interactions

BAZ1B RBM28

1.51e-03119102int:TEK
InteractionISG15 interactions

AHNAK RBM28 UBTF

1.54e-03494103int:ISG15
InteractionBRD3 interactions

BAZ1B HMGB3 UBTF

1.54e-03494103int:BRD3
InteractionH3C3 interactions

BAZ1B HMGB3 UBTF

1.55e-03495103int:H3C3
InteractionPNMA8A interactions

RBM28 UBTF

1.58e-03122102int:PNMA8A
InteractionRNF151 interactions

RBM28 UBTF

1.61e-03123102int:RNF151
InteractionETV3 interactions

BAZ1B RBM28

1.74e-03128102int:ETV3
InteractionDDR2 interactions

BAZ1B RBM28

1.96e-03136102int:DDR2
InteractionNPM1 interactions

BAZ1B HIVEP2 RBM28 LECT2

1.97e-031201104int:NPM1
InteractionUSP53 interactions

BAZ1B RBM28

2.02e-03138102int:USP53
InteractionFBXW7 interactions

AHNAK BAZ1B RBM28 UBTF

2.06e-031215104int:FBXW7
InteractionMERTK interactions

BAZ1B RBM28

2.08e-03140102int:MERTK
InteractionCST1 interactions

TADA3 HMGB3

2.11e-03141102int:CST1
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK LECT2

5.14e-041541021e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellfacs-Brain_Myeloid-Cerebellum|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK HMGB3

5.28e-0415610228c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRS4 HMGB3

5.97e-041661021f39c7507ac6881aa1a30f8be22f98a1837d926b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK HIVEP2

6.04e-04167102ced6ed9b412739c6ced622523347c10295edbf53
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK LECT2

6.26e-04170102ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK LECT2

6.26e-04170102a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRS4 HMGB3

6.41e-04172102bd01b39a5699824ab14827cc9dc98e547d65b160
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B HIVEP2

6.48e-04173102a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B HIVEP2

6.48e-04173102639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRS4 HMGB3

6.56e-04174102911eac6f6ec1e5e85348a7fe774243498388a810
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

BAZ1B UBTF

6.94e-0417910268511e87b12b8253de7771e5ccfc5869248b8450
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BAZ1B

7.33e-041841021154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TADA3 HMGB3

7.48e-04186102bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM28 HMGB3

7.81e-0419010236e83995021ba16690f84e2077a9e8baec547d05
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM28 HMGB3

7.81e-04190102d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AHNAK HIVEP2

7.97e-04192102ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AHNAK HIVEP2

7.97e-04192102b016e229300c183e14c0e2bba494bf49c7899112
ToppCellfacs-SCAT-Fat-18m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK HIVEP2

7.97e-04192102cd004f8b00ebdb7f6d889f58d2cd6cbab4b809dd
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK HIVEP2

8.05e-04193102194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B HIVEP2

8.14e-041941028ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BAZ1B HMGB3

8.30e-04196102de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCellproximal-Epithelial-Ionocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 HMGB3

8.39e-04197102e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCellproximal-Epithelial-Ionocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 HMGB3

8.39e-04197102f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIVEP2 HMGB3

8.39e-041971020f37afad46b94c748a149d9ee681472d7a3e6937
ToppCellproximal-3-Epithelial-Ionocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 HMGB3

8.39e-04197102288492fc67d8e81349d38e82caf1f1890276b299
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

HIVEP2 HMGB3

8.39e-041971022cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

AHNAK RBM28

8.39e-041971020fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell(2)_Fibroblasts-(24)_Fibro-5|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

AHNAK HIVEP2

8.39e-0419710283a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HIVEP2 HMGB3

8.39e-041971024f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

AHNAK HIVEP2

8.47e-041981026333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_small-bowel / Manually curated celltypes from each tissue

AHNAK HIVEP2

8.56e-04199102508a6efc11b1b45899a968888865731088cac668
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

RBM28 HMGB3

8.64e-042001024e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

RBM28 HMGB3

8.64e-042001029769185abae084ffac36420c749625e679b70ca8
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

RBM28 HMGB3

8.64e-042001026e367abd1a4b87e20eb9095b8337723163e8bbae
DrugAC1L36FJ

HMGB3 UBTF

3.63e-0521102CID000083911
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

BAZ1B HIVEP2 UBTF

5.06e-051741037105_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

BAZ1B HIVEP2 UBTF

5.42e-051781035086_DN
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A

AHNAK BAZ1B UBTF

6.47e-051891035208_DN
DrugGabazine [105538-73-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A

HMGXB3 BAZ1B HIVEP2

6.57e-051901033253_DN
Drugprochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A

BAZ1B HIVEP2 TADA3

7.10e-051951031156_UP
DrugDequalinium dichloride [522-51-0]; Up 200; 7.6uM; HL60; HT_HG-U133A

AHNAK BAZ1B TADA3

7.21e-051961031276_UP
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

HMGXB3 HIVEP2 TADA3

7.21e-051961031021_DN
DrugZuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A

HMGXB3 AHNAK BAZ1B

7.21e-051961032936_DN
DrugTocainide hydrochloride; Down 200; 17.4uM; HL60; HT_HG-U133A

HMGXB3 AHNAK BAZ1B

7.32e-051971032931_DN
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; HL60; HT_HG-U133A

HMGXB3 HIVEP2 UBTF

7.32e-051971032463_DN
DrugLovastatin [75330-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

HMGXB3 TADA3 UBTF

7.32e-051971032854_DN
DrugNaftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2 UBTF

7.43e-051981037032_DN
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

AHNAK IRS4 HIVEP2

7.43e-051981036907_UP
DrugDexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A

AHNAK IRS4 BAZ1B

7.43e-051981032242_UP
DrugXylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A

HMGXB3 HIVEP2 UBTF

7.54e-051991037020_DN
Drugpioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A

AHNAK IRS4 HIVEP2

7.54e-051991035925_DN
DrugDoxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; PC3; HT_HG-U133A

BAZ1B HIVEP2 UBTF

7.54e-051991036337_DN
DrugTetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; PC3; HT_HG-U133A

AHNAK TADA3 LECT2

7.54e-051991035728_UP
DrugArecoline hydrobromide [300-08-3]; Down 200; 17uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2 TADA3

7.54e-051991035423_DN
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A

AHNAK IRS4 TADA3

7.66e-052001036128_UP
Drugd(GpG

HMGB3 UBTF

1.03e-0435102CID000161113
Drugalpha-GalCer

BAZ1B LECT2

1.43e-03131102CID002826713
DrugAGN 194204

AHNAK HMGB3

2.18e-03162102ctd:C430898
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.45e-031721024344_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.45e-031721026439_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.45e-031721027073_DN
DrugMG-262; Down 200; 0.1uM; PC3; HT_HG-U133A

AHNAK HIVEP2

2.48e-031731027068_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.48e-031731024565_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

BAZ1B UBTF

2.51e-031741025580_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

BAZ1B UBTF

2.51e-031741025065_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.54e-031751026736_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.54e-031751025908_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

HIVEP2 UBTF

2.57e-031761021535_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BAZ1B UBTF

2.60e-031771023227_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

BAZ1B UBTF

2.62e-031781024436_DN
DrugSAHA; Down 200; 10uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.62e-031781024444_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BAZ1B UBTF

2.62e-031781024710_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.65e-031791026609_DN
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

IRS4 UBTF

2.65e-03179102331_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.65e-031791024483_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BAZ1B UBTF

2.68e-031801026454_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.68e-031801025981_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.71e-031811027077_DN
Drug15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.74e-031821021231_DN
DrugRifabutin [72559-06-9]; Down 200; 4.8uM; PC3; HT_HG-U133A

BAZ1B UBTF

2.77e-031831024527_DN
DrugF0447-0125; Down 200; 10uM; PC3; HT_HG-U133A

AHNAK HIVEP2

2.80e-031841026429_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.80e-031841027555_DN
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

BAZ1B HIVEP2

2.86e-031861024463_UP
DrugPimozide [2062-78-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

AHNAK LECT2

2.86e-031861023178_UP
DrugDexamethasone acetate [1177-87-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

HIVEP2 UBTF

2.92e-031881022079_DN
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

HMGXB3 UBTF

2.92e-031881024845_DN
DrugLansoprazole [103577-45-3]; Down 200; 10.8uM; HL60; HT_HG-U133A

AHNAK HIVEP2

2.95e-031891022967_DN
DrugSecurinine [5610-40-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A

HIVEP2 TADA3

2.95e-031891026831_DN
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

AHNAK BAZ1B

2.95e-031891022231_UP
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A

HMGXB3 AHNAK

2.98e-031901021636_DN
DrugLidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A

AHNAK BAZ1B

2.98e-031901024421_DN
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2

3.01e-031911026024_DN
DrugLY294002; Up 200; 10uM; PC3; HT_HG-U133A

AHNAK TADA3

3.01e-031911025970_UP
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A

HMGXB3 UBTF

3.01e-031911027376_DN
DrugThiostrepton [1393-48-2]; Down 200; 2.4uM; PC3; HT_HG-U133A

HIVEP2 UBTF

3.01e-031911024563_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

HIVEP2 UBTF

3.01e-031911027503_DN
DrugTiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2

3.04e-031921022292_DN
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

AHNAK BAZ1B

3.04e-031921022123_UP
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A

BAZ1B UBTF

3.04e-031921022271_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

IRS4 TADA3

3.04e-031921022523_UP
DrugNitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A

AHNAK IRS4

3.04e-031921023087_UP
Drug5707885; Down 200; 50uM; PC3; HT_HG-U133A

AHNAK BAZ1B

3.04e-031921026438_DN
DrugEthynodiol diacetate [297-76-7]; Up 200; 10.4uM; PC3; HT_HG-U133A

AHNAK BAZ1B

3.08e-031931026678_UP
DrugSTOCK1N-35215; Down 200; 10uM; MCF7; HT_HG-U133A

HIVEP2 UBTF

3.08e-031931026422_DN
Drugionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA

HMGXB3 UBTF

3.08e-03193102979_DN
Drugphenanthridinone; Up 200; 51.2uM; MCF7; HT_HG-U133A_EA

BAZ1B RBM28

3.08e-031931021115_UP
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; PC3; HT_HG-U133A

HIVEP2 UBTF

3.08e-031931026751_DN
Drug3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A

AHNAK BAZ1B

3.08e-031931024426_DN
DrugEtilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; HL60; HT_HG-U133A

AHNAK UBTF

3.08e-031931022930_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2

3.08e-031931024410_DN
DrugGraveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2

3.08e-031931023614_DN
DrugButoconazole nitrate [32872-77-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

HIVEP2 LECT2

3.11e-031941023288_UP
DrugPrilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A

TADA3 UBTF

3.11e-031941024284_DN
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A

TADA3 UBTF

3.11e-031941024331_DN
Drug5194442; Up 200; 20uM; PC3; HT_HG-U133A

AHNAK BAZ1B

3.11e-031941026553_UP
Drugnordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A

HMGXB3 UBTF

3.11e-031941021223_DN
DrugUrapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A

TADA3 UBTF

3.11e-031941026696_UP
DrugICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A

BAZ1B HIVEP2

3.11e-031941021205_UP
DrugSyrosingopine [84-36-6]; Down 200; 6uM; MCF7; HT_HG-U133A

BAZ1B UBTF

3.11e-031941022753_DN
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

IRS4 HIVEP2

3.11e-031941024961_UP
Drug17-AAG; Down 200; 1uM; MCF7; HG-U133A

TADA3 UBTF

3.11e-03194102428_DN
DrugMethyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

TADA3 UBTF

3.11e-031941024325_DN
Drug2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A

BAZ1B TADA3

3.11e-031941026199_DN
DrugButoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A

AHNAK TADA3

3.11e-031941022427_DN
DrugSparteine (-) [90-39-1]; Down 200; 17uM; MCF7; HT_HG-U133A

BAZ1B HIVEP2

3.11e-031941024391_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; HL60; HT_HG-U133A

BAZ1B TADA3

3.14e-031951022432_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

HMGXB3 AHNAK

3.14e-031951021045_UP
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

HMGXB3 AHNAK BAZ1B

4.25e-0523993EFO_0010934
Diseaseintellectual disability (implicated_via_orthology)

IRS4 HIVEP2

2.27e-047592DOID:1059 (implicated_via_orthology)
DiseaseIntellectual Disability

HIVEP2 RBM28 HMGB3

2.71e-0444793C3714756
Diseasemigraine disorder

HMGXB3 BAZ1B

4.97e-0335792MONDO_0005277
Diseasebirth weight

BAZ1B HIVEP2

6.17e-0339992EFO_0004344
Diseasecystatin C measurement

BAZ1B HIVEP2

6.26e-0340292EFO_0004617
Diseaseuric acid measurement

BAZ1B UBTF

1.40e-0261092EFO_0004761
Diseasemonocyte percentage of leukocytes

HMGXB3 AHNAK

1.97e-0273192EFO_0007989
Diseaseeosinophil percentage of leukocytes

HIVEP2 LECT2

2.04e-0274692EFO_0007991

Protein segments in the cluster

PeptideGeneStartEntry
ELGAPPKHGKPKKQK

TADA3

91

O75528
PKHGKPKKQKLEGKA

TADA3

96

O75528
KKGPPAKKPGKHSDK

BAZ1B

386

Q9UIG0
KIPKFKKPKFGFGAK

AHNAK

4971

Q09666
KGKVKPVHPKKPKPQ

RBM28

686

Q9NW13
PGPPKKKKKYKIHGE

HMGXB3

26

Q12766
KPIKYKGPIKKGEKL

LECT2

106

O14960
KDYGPAKGGKKKKDP

HMGB3

76

O15347
TKGYKIKPKPQKPTH

IRS4

896

O14654
VKNPYKGKKLKKHPD

UBTF

96

P17480
KGKKLKKHPDFPKKP

UBTF

101

P17480
AHKKEHKPKKPGKYI

HIVEP2

176

P31629