Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1B CACNA1D CACNA1E

2.99e-0591443GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1B CACNA1D CACNA1E

2.99e-0591443GO:0099626
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1B CACNA1D CACNA1E

1.26e-04141443GO:0008331
GeneOntologyBiologicalProcesscilium assembly

SPAG1 SYNE1 SPEF2 TTC36 ARMC2 ASAP1 DNAH1 ARL3 ATP6V1D SNX10 CC2D2A CFAP74 CEP19

1.36e-0544414313GO:0060271
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

SPAG1 RAPGEF6 PODXL SYNE1 SPEF2 APC TTC36 ARMC2 ASAP1 DNAH1 ARL3 ATP6V1D SNX10 CC2D2A CFAP74 CEP19

1.71e-0567014316GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

SPAG1 RAPGEF6 PODXL SYNE1 SPEF2 APC TTC36 ARMC2 ASAP1 DNAH1 ARL3 ATP6V1D SNX10 CC2D2A CFAP74 CEP19

2.24e-0568514316GO:0030031
GeneOntologyBiologicalProcesscilium organization

SPAG1 SYNE1 SPEF2 TTC36 ARMC2 ASAP1 DNAH1 ARL3 ATP6V1D SNX10 CC2D2A CFAP74 CEP19

2.81e-0547614313GO:0044782
HumanPhenoObesity

MYT1L MIA3 ATRX SYNE1 CDHR1 SKI GHR SETD2 ARL3 KLHL7 RTL1 CC2D2A TAF1 RERE SPEN PHIP CEP19

9.25e-064256317HP:0001513
HumanPhenoIncreased body weight

MYT1L MIA3 ATRX SYNE1 CDHR1 SKI GHR KMT2C SETD2 ARL3 KLHL7 RTL1 CC2D2A TAF1 RERE SPEN PHIP CEP19

1.59e-054916318HP:0004324
HumanPhenoFunctional abnormality of the middle ear

CACNA1B SPAG1 CDHR1 SPEF2 SKI DNAH1 SETD2 ARL3 OTOF KLHL7 CC2D2A CFAP74 TSHZ1 RERE SPEN

4.96e-053866315HP:0011452
HumanPhenoPuberty and gonadal disorders

MYT1L SOX11 SPAG1 MIA3 ATRX CDHR1 SPEF2 WRN SKI ZFPM2 DNAH1 GHR KMT2C SETD2 ARL3 KLHL7 RTL1 FIP1L1 CC2D2A RNF216 CFAP74 RERE SPEN CEP19

9.07e-059006324HP:0008373
HumanPhenoAnteverted nares

CACNA1B SOX11 IRX5 ATRX APC SKI SETD2 ARL3 PIEZO2 TRPM3 RTL1 CC2D2A TAF1 RERE SPEN PHIP DYNC1I2 KIF11

9.14e-055596318HP:0000463
HumanPhenoUpturned nose

CACNA1B SOX11 IRX5 ATRX APC SKI SETD2 ARL3 PIEZO2 TRPM3 RTL1 CC2D2A TAF1 RERE SPEN PHIP DYNC1I2 KIF11

9.14e-055596318HP:0000427
HumanPhenoLong nose

SOX11 SETD2 PIEZO2 TRPM3 ZBTB18

1.31e-0441635HP:0003189
HumanPhenoAbnormal nostril morphology

CACNA1B SOX11 IRX5 ATRX APC SKI SETD2 ARL3 PIEZO2 TRPM3 RTL1 CC2D2A TAF1 RERE SPEN PHIP DYNC1I2 KIF11

1.32e-045756318HP:0005288
HumanPhenoConductive hearing impairment

CACNA1B SPAG1 CDHR1 SPEF2 SKI DNAH1 SETD2 ARL3 KLHL7 CC2D2A CFAP74 TSHZ1 RERE SPEN

1.36e-043736314HP:0000405
HumanPhenoAbnormal male reproductive system physiology

MYT1L SOX11 SPAG1 EVC2 IRX5 ATRX PODXL SYNE1 CDHR1 SPEF2 WRN SKI ARMC2 ZFPM2 DNAH1 KMT2C ARL3 PIEZO2 TRPM3 SACS KLHL7 RTL1 CC2D2A CFAP74 KDR RERE SPEN PHIP DSE CEP19

1.43e-0413146330HP:0012874
HumanPhenoProminent stem of antihelix

TCF3 RERE

1.51e-042632HP:0011240
HumanPhenoAbnormality of stem of antihelix

TCF3 RERE

1.51e-042632HP:0011244
HumanPhenoDilatation of the renal pelvis

MIA3 ATRX APC SKI ARL3 PIEZO2 RTL1 RERE SPEN ZBTB18 DSE CEP19

1.79e-042906312HP:0010946
HumanPhenoThin vermilion border

SOX11 EVC2 IRX5 ATRX APC ZFPM2 PIEZO2 CLCN6 KDR TAF1 SPEN ZBTB18 PHIP DSE KIF11

1.84e-044336315HP:0000233
HumanPhenoAbnormal renal pelvis morphology

MIA3 ATRX APC SKI ARL3 PIEZO2 RTL1 RERE SPEN ZBTB18 DSE CEP19

2.46e-043006312HP:0010944
HumanPhenoFinger clinodactyly

MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RTL1 RNF216 KDR RERE SPEN PHIP CEP19

2.96e-044526315HP:0040019
HumanPhenoTapered finger

IRX5 ATRX KMT2C TRPM3 TNNT3 SPEN PHIP DSE

3.02e-04141638HP:0001182
HumanPhenoBilateral talipes equinovarus

MYT1L SYNE1 PIEZO2 TRPM3 DSE

3.09e-0449635HP:0001776
HumanPhenoAbdominal situs inversus

SPAG1 EVC2 SPEF2 DNAH1 ARL3 PIEZO2 CC2D2A CFAP74

3.17e-04142638HP:0003363
HumanPhenoSitus inversus totalis

SPAG1 EVC2 SPEF2 DNAH1 ARL3 PIEZO2 CC2D2A CFAP74

3.17e-04142638HP:0001696
HumanPhenoAbnormal spatial orientation of the cardiac segments

SPAG1 EVC2 SPEF2 DNAH1 ARL3 PIEZO2 CC2D2A CFAP74

3.17e-04142638HP:0011534
HumanPhenoAbnormality of abdominal situs

SPAG1 EVC2 SPEF2 DNAH1 ARL3 PIEZO2 CC2D2A CFAP74

3.17e-04142638HP:0011620
HumanPhenoHydronephrosis

MIA3 ATRX APC SKI ARL3 PIEZO2 RTL1 RERE SPEN DSE CEP19

3.26e-042646311HP:0000126
HumanPhenoAbnormal 5th finger morphology

SOX11 MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 CC2D2A RNF216 KDR RERE SPEN PHIP CEP19

3.31e-045096316HP:0004207
HumanPhenoHeterotaxy

SPAG1 EVC2 SPEF2 DNAH1 ARL3 PIEZO2 CC2D2A CFAP74

3.66e-04145638HP:0030853
HumanPhenoClinodactyly

SOX11 MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RTL1 RNF216 KDR RERE TNNT3 SPEN PHIP CEP19

4.19e-045746317HP:0030084
HumanPhenoClinodactyly of the 5th finger

MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RNF216 KDR RERE SPEN PHIP CEP19

4.70e-044206314HP:0004209
HumanPhenoClinodactyly of hands

MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RNF216 KDR RERE SPEN PHIP CEP19

4.82e-044216314HP:0001157
HumanPhenoDeviation of the 5th finger

MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RNF216 KDR RERE SPEN PHIP CEP19

4.82e-044216314HP:0009179
HumanPhenoAbnormal morphology of the nasal alae

CACNA1B SOX11 IRX5 ATRX APC SKI SETD2 ARL3 PIEZO2 TRPM3 RTL1 CC2D2A TAF1 RERE SPEN PHIP DYNC1I2 KIF11

5.01e-046396318HP:0000429
HumanPhenoFunctional abnormality of male internal genitalia

MYT1L SOX11 SPAG1 EVC2 IRX5 ATRX SYNE1 CDHR1 SPEF2 WRN SKI ARMC2 ZFPM2 DNAH1 KMT2C ARL3 PIEZO2 TRPM3 KLHL7 RTL1 CC2D2A CFAP74 KDR RERE SPEN PHIP DSE CEP19

5.26e-0412696328HP:0000025
HumanPhenoAbnormal cheek morphology

MYT1L SOX11 IRX5 ZFPM2 TRPM3 KLHL7 RTL1 CC2D2A KDR RERE KIF11

5.74e-042826311HP:0004426
HumanPhenoAbnormal midface morphology

MYT1L SOX11 IRX5 ATRX APC SKI ZFPM2 GHR KMT2C SETD2 TRPM3 KLHL7 RTL1 CC2D2A KDR RERE SPEN DSE KIF11

5.75e-047046319HP:0000309
HumanPhenoLong philtrum

IRX5 SYNE1 APC SKI PIEZO2 CLCN6 RTL1 TAF1 RERE SPEN PHIP DSE KIF11 CEP19

5.83e-044296314HP:0000343
HumanPhenoCoiled sperm flagella

SPEF2 ARMC2 DNAH1 CFAP74

5.89e-0432634HP:0032560
HumanPhenoDeviation of finger

MIA3 EVC2 IRX5 ATRX SKI ZFPM2 PIEZO2 TRPM3 RTL1 RNF216 KDR RERE TNNT3 SPEN PHIP CEP19

6.07e-045376316HP:0004097
DomainDUF1220

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

1.13e-08111445PF06758
DomainNBPF_dom

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

1.13e-08111445IPR010630
DomainNBPF

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

1.13e-08111445PS51316
DomainDUF1220

NBPF3 NBPF11 NBPF1 NBPF9

4.14e-0791444SM01148
DomainCa_chan_IQ

CACNA1B CACNA1D CACNA1E

1.54e-0571443SM01062
DomainCa_chan_IQ

CACNA1B CACNA1D CACNA1E

1.54e-0571443PF08763
DomainVDCC_a1su_IQ

CACNA1B CACNA1D CACNA1E

1.54e-0571443IPR014873
DomainGPHH

CACNA1B CACNA1D CACNA1E

1.54e-0571443PF16905
DomainGPHH_dom

CACNA1B CACNA1D CACNA1E

1.54e-0571443IPR031649
DomainBromodomain_CS

BAZ1A TAF1 TAF1L PHIP

4.44e-05261444IPR018359
DomainVDCCAlpha1

CACNA1B CACNA1D CACNA1E

5.18e-05101443IPR002077
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

5.90e-0521442IPR022591
DomainTBP-binding

TAF1 TAF1L

5.90e-0521442PF09247
DomainDUF3591

TAF1 TAF1L

5.90e-0521442PF12157
DomainTAF_II_230-bd

TAF1 TAF1L

5.90e-0521442IPR009067
Domain-

TAF1 TAF1L

5.90e-05214421.10.1100.10
DomainTAF1_animal

TAF1 TAF1L

5.90e-0521442IPR011177
DomainBROMODOMAIN_1

BAZ1A TAF1 TAF1L PHIP

1.84e-04371444PS00633
DomainBromodomain

BAZ1A TAF1 TAF1L PHIP

2.04e-04381444PF00439
DomainBROMODOMAIN_2

BAZ1A TAF1 TAF1L PHIP

2.75e-04411444PS50014
DomainBromodomain

BAZ1A TAF1 TAF1L PHIP

3.02e-04421444IPR001487
DomainBROMO

BAZ1A TAF1 TAF1L PHIP

3.02e-04421444SM00297
Domain-

BAZ1A TAF1 TAF1L PHIP

3.02e-044214441.20.920.10
DomainTIF_beta_prop-like

WDHD1 EIF3B

5.81e-0451442IPR013979
DomaineIF2A

WDHD1 EIF3B

5.81e-0451442PF08662
DomainHMG_BOX_2

SOX11 BBX WDHD1 TAF1

7.95e-04541444PS50118
DomainHMG

SOX11 KMT2C BBX WDHD1

7.95e-04541444SM00398
DomainIRO

IRX5 IRX4

8.68e-0461442SM00548
DomainIroquois_homeo

IRX5 IRX4

8.68e-0461442IPR003893
DomainHMG_box_dom

SOX11 KMT2C BBX WDHD1

1.59e-03651444IPR009071
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF3 NBPF8 NBPF12 NBPF11 NBPF1 NBPF19 NBPF9 NBPF10 NBPF14

1.63e-1621156916079250
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12 NBPF1 NBPF9 NBPF14

4.21e-1010156522973535
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 SPAG1 SFPQ NBPF12 TTC36 NBPF11 NBPF1 NBPF9 NBPF10 NBPF14

5.66e-091701561023314748
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

STRN3 ATRX BMP2K SYNE1 WRN APC ARHGEF12 NBPF26 SRPK2 DAXX NOL9 DDX27 GRSF1 DHX8 PRR12 KMT2C ESYT2 SETD2 NOP14 BBX BAZ1A METTL18 EIF3B SPEN TAF1L

1.45e-0814971562531527615
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 SYNE1 SPEF2 NBPF1 SETD2 SPHKAP CFAP74 EXOC4

2.10e-08102156811214970
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1E STRN3 SPAG1 SFPQ ANK2 ATRX SYNE1 SPEF2 U2SURP MAGI3 SKI NOP14 BBX SACS SETSIP BAZ1A CC2D2A CFAP74 KDR SPEN DYNC1I2 PRRC2B KIF11 DOP1A

3.11e-0814421562435575683
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CUL1 STRN3 SFPQ MIA3 BMP2K SYNE1 SRPK2 NOL9 TIMMDC1 DDX27 GRSF1 TMX1 ESYT2 NOP14 CLMN OSBPL11 RERE C9orf72 ACBD3 PHIP SOAT1 PRRC2B USP33 EXOC4

6.17e-0814961562432877691
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 CACNA1E NES STRN3 SFPQ MIA3 ANK2 SYNE1 APC ARHGEF12 SRPK2 NOL9 GRM1 FRY KLHL7 SPHKAP GIGYF2 PRRC2B KIF11

7.35e-089631561928671696
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

STRN3 RAPGEF6 ATRX DAXX TMX1 ESYT2 SETD2 WDHD1 FHOD1 OSBPL11 FIP1L1 PLA2G4A GIGYF2 EIF3B RERE SPEN DYNC1I2

8.31e-087741561715302935
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L SFPQ MIA3 RAPGEF6 ATRX BMP2K APC DDI2 NOL9 SLC39A10 GRSF1 ASAP1 KMT2C WDHD1 BAZ1A CLMN OSBPL11 ANKRD40 DSE KIF11

9.60e-0810841562011544199
Pubmed

Genomic analysis of mouse retinal development.

CUL1 SOX11 NES TCF3 YIPF4 CDHR1 APC SRPK2 RNF187 CCDC43 ARL3 TRPM3 SPHKAP NUB1 SNCB SLC24A1 PRRC2B IP6K2 USP33

1.44e-0710061561915226823
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TANC2 CACNA1B CACNA1E HSP90B2P ATRX APC ARHGEF12 MAGI3 PRR12 FRY CLMN PHIP PRRC2B

2.59e-074751561331040226
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC42BPG MIA3 RAPGEF6 ATRX APC SRPK2 NOL9 NPLOC4 PRR12 OSBPL11 GIGYF2 RNF216 PRRC2B USP33 EXOC4

2.69e-076501561538777146
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

MIA3 TMEM87A NPLOC4 TMX1 CCDC43 ESYT2 OSBPL11 PLA2G4A GIGYF2 C9orf72 ACBD3 SOAT1 USP33 EXOC4

3.12e-075681561437774976
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

STRN3 MIA3 BMP2K DIS3L APC MAGI3 KLC4 DDX27 ASAP1 CCDC43 ESYT2 KLHL7 PPM1F GIGYF2 DYNC1I2 PRRC2B EXOC4

3.26e-078531561728718761
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L ANK2 ATRX DIS3L SYNE1 APC MAGI3 SRPK2 BLOC1S2 DDX27 FRY ZNF532 OTOF SACS KLHL7 FIP1L1 RNF216 TAF1 ACBD3 USP33 EXOC4

3.33e-0712851562135914814
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 NBPF12 SYNE1 SLC39A10 ASAP1 PRR12 ESYT2

4.41e-07103156710574462
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF8 SFPQ NBPF12 ABCA13 U2SURP SLC39A10 NBPF11 NBPF1 PRR12 NBPF9 NBPF10 NBPF14 DSE

6.16e-075131561325798074
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1B CACNA1D CACNA1E

8.79e-075156311296258
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1B CACNA1D CACNA1E

8.79e-075156315451373
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

RAPGEF6 ATRX SYNE1 CHMP4BP1 ARMC2 IRX4 BBX KIF11

9.91e-07168156830631154
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

STRN3 SFPQ RAPGEF6 ANK2 ATRX U2SURP NPLOC4 CCDC43 SETD2 BAZ1A CLMN FHOD1 OSBPL11 GIGYF2 ACBD3 PRRC2B KIF11

1.13e-069341561733916271
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CUL1 TCF3 SFPQ ATRX U2SURP WRN NOL9 SKI DHX8 PRR12 KMT2C ESYT2 SETD2 PRDM11 BBX BAZ1A FIP1L1 SPEN TAF1L SOAT1

1.53e-0612941562030804502
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

CUL1 SFPQ U2SURP SRPK2 DAXX DDX27 GRSF1 ESYT2 NOP14 WDHD1 FIP1L1 NUB1 EIF3B KIF11

1.62e-066531561433742100
Pubmed

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

SOX11 RNF187 ZFPM2 SPON1

2.20e-0621156424057671
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 BDP1 CDC42BPG TCF3 MIA3 ATRX MAGI3 SRPK2 SKI ARMC2 NPLOC4 NBPF1 DNAH1 KMT2C ZBTB46 ESYT2 ZNF532 CLMN RERE DOP1A EXOC4

3.46e-0614891562128611215
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PRUNE2 RAPGEF6 GRM1 ASAP1 NBPF19 ZNF532 NBPF9 KDR TSHZ1 SPEN NBPF14

4.25e-064301561135044719
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CACNA1B HSP90B2P ABCA13 SPEF2 KMT2C SPEN KIF11 DOP1A

4.86e-06208156833230847
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1B CACNA1D CACNA1E

4.88e-068156328330839
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TANC2 CUL1 SPAG1 PODXL YIPF4 SYNE1 APC MAGI3 TMEM87A KSR1 NOP14 FHOD1 OSBPL11 KIF11

4.91e-067191561435337019
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ABCA13 ARHGEF12 SRPK2 GHR OTOF BAZ1A FIP1L1 SPEN PRRC2B KIF11

5.88e-063611561026167880
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

ANK2 ARHGEF12 TMEM87A NPLOC4 TMX1 OSBPL11 GIGYF2 RAB15 ACBD3 USP33 KIF11

6.39e-064491561131732153
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

CUL1 SFPQ ATRX SYNE1 U2SURP NOL9 GRM1 DDX27 GRSF1 DHX8 TMX1 BAZ1A CC2D2A GIGYF2 EIF3B TDRD6 SPEN PHIP SOAT1 KIF11

6.49e-0614251562030948266
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

ATRX TAF1 TAF1L

7.29e-06915637874112
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 NES RAPGEF6 APC MAGI3 KLC4 KSR1 ESYT2 CLMN FIP1L1 GIGYF2 NUB1 KIF11 DOP1A EXOC4

8.44e-068611561536931259
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYT1L PRUNE2 SYNE1 KMT2C ESYT2 CLCN6 SPON1 GIGYF2

8.64e-06225156812168954
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

TCF3 ZFPM2 PRR12 BBX SPEN PHIP

1.02e-05109156633554859
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CUL1 NES SFPQ U2SURP SNX17 NOL9 DDX27 GRSF1 ASAP1 NOP14 BAZ1A PPM1F FHOD1 FIP1L1 EIF3B PHIP DYNC1I2 KIF11 EXOC4

1.12e-0513531561929467282
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

STRN3 DIS3L U2SURP SRPK2 NOL9 ESYT2 NOP14 WDHD1 FIP1L1 RNF216 NUB1 EIF3B DYNC1I2

1.13e-056701561322990118
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MIA3 ANK2 ATRX SYNE1 SRPK2 NOL9 SLC39A10 TIMMDC1 DDX27 GRSF1 TMX1 ESYT2 NOP14 SACS CLMN C9orf72 ACBD3 SOAT1 USP33 EXOC4

1.21e-0514871562033957083
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

CUL1 STRN3 WRN APC MAGI3 BLOC1S2 NPLOC4 DHX8 SHQ1 EIF4EBP3 OSBPL11 GIGYF2 EIF3B PRRC2B USP33 KIF11

1.28e-0510051561619615732
Pubmed

A human MAP kinase interactome.

SFPQ SYNE1 APC DAXX DDX27 ASAP1 KMT2C FHOD1 GIGYF2 TAF1 ZBTB18

1.34e-054861561120936779
Pubmed

Y chromosome damage underlies testicular abnormalities in ATR-X syndrome.

ATRX DAXX ZFPM2

1.42e-0511156338616920
Pubmed

DNA cloning using in vitro site-specific recombination.

NBPF3 CUL1 EVC2 YIPF4 APC COA4 GRM1 TIMMDC1 ARMC2 FIP1L1 RNF216 DYNC1I2 DRC3 EXOC4

1.50e-057941561411076863
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CUL1 STRN3 PODXL APC NPLOC4 KMT2C KSR1 ESYT2 WDHD1 TRPM3 CLMN TAF1L PRRC2B

1.51e-056891561336543142
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TANC2 PRUNE2 DIS3L MAGI3 PRR12 SETD2 TRPM3 SACS SPON1 DOP1A EXOC4

1.53e-054931561115368895
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SYNE1 ARHGEF12 SLC39A10 ASAP1 SPHKAP GIGYF2 RERE SPEN PRRC2B USP33

1.66e-054071561012693553
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SNX17 SLC39A10 TMEM87A BLOC1S2 TMX1 ESYT2 OSBPL11 C9orf72 ACBD3 SOAT1 USP33

1.87e-055041561134432599
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TANC2 STRN3 TCF3 RAPGEF6 BMP2K DIS3L SNX17 DAXX NOL9 SHQ1 KSR1 SETD2 WDHD1 FIP1L1 GIGYF2 RNF216

1.89e-0510381561626673895
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

ATRX U2SURP SRPK2 NOL9 BAZ1A GIGYF2 SPEN PRRC2B

1.90e-05251156828077445
Pubmed

DAXX, ATRX, and MSI in PanNET and Their Metastases: Correlation with Histopathological Data and Prognosis.

ATRX DAXX

2.00e-052156235691289
Pubmed

Identification and characterisation of a novel GHR defect disrupting the polypyrimidine tract and resulting in GH insensitivity.

SFPQ GHR

2.00e-052156219812236
Pubmed

Daxx inhibits muscle differentiation by repressing E2A-mediated transcription.

TCF3 DAXX

2.00e-052156219308989
Pubmed

ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.

ATRX DAXX

2.00e-052156231454099
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

2.00e-052156215610184
Pubmed

Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.

ATRX DAXX

2.00e-052156227578458
Pubmed

Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.

APC SETD2

2.00e-052156228825595
Pubmed

Alternative Lengthening of Telomeres in Primary Pancreatic Neuroendocrine Tumors Is Associated with Aggressive Clinical Behavior and Poor Survival.

ATRX DAXX

2.00e-052156227663587
Pubmed

Compromised Telomeric Heterochromatin Promotes ALTernative Lengthening of Telomeres.

ATRX DAXX

2.00e-052156228741530
Pubmed

Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors.

ATRX DAXX

2.00e-052156227407094
Pubmed

Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis.

CACNA1D ANK2

2.00e-052156223436330
Pubmed

Suppression of intestinal polyposis in Apc(delta 716) knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene.

APC PLA2G4A

2.00e-052156210969066
Pubmed

Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors.

ATRX DAXX

2.00e-052156228371511
Pubmed

Clinicopathologic significance of immunostaining of α-thalassemia/mental retardation syndrome X-linked protein and death domain-associated protein in neuroendocrine tumors.

ATRX DAXX

2.00e-052156223954140
Pubmed

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies.

ATRX DAXX

2.00e-052156212953102
Pubmed

Structural basis for DAXX interaction with ATRX.

ATRX DAXX

2.00e-052156228875424
Pubmed

EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription.

ATRX DAXX

2.00e-052156222102817
Pubmed

A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein.

ATRX DAXX

2.00e-052156214990586
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

2.00e-052156238804708
Pubmed

The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71.

ATRX DAXX

2.00e-052156223135716
Pubmed

The dynamics of DAXX protein distribution in the nucleus of mouse early embryos.

ATRX DAXX

2.00e-052156231029404
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

2.00e-052156222842574
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

2.00e-052156227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

2.00e-052156234403156
Pubmed

Altered telomeres in tumors with ATRX and DAXX mutations.

ATRX DAXX

2.00e-052156221719641
Pubmed

Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL.

PLA2G4A SOAT1

2.00e-052156225617738
Pubmed

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone.

ATRX DAXX

2.00e-052156226773061
Pubmed

Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.

ATRX DAXX

2.00e-052156224148618
Pubmed

Clinical features of ATRX or DAXX mutated neuroblastoma.

ATRX DAXX

2.00e-052156225487495
Pubmed

Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.

NBPF11 NBPF1

2.00e-05215627700633
Pubmed

Loss of ATRX and DAXX in pancreatic neuroendocrine tumors: Association with recurrence risk, cellular phenotype, and heterogeneity.

ATRX DAXX

2.00e-052156238909708
Pubmed

Single-cell analysis of Daxx and ATRX-dependent transcriptional repression.

ATRX DAXX

2.00e-052156222976303
Pubmed

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation.

CACNA1D ANK2

2.00e-052156221859974
Pubmed

Loss of ATRX/DAXX expression and alternative lengthening of telomeres in uterine leiomyomas.

ATRX DAXX

2.00e-052156230423196
Pubmed

Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx.

ATRX DAXX

2.00e-052156220147399
Pubmed

Impact of DAXX and ATRX expression on telomere length and prognosis of breast cancer patients.

ATRX DAXX

2.00e-052156232856116
Pubmed

ATRX and DAXX: Mechanisms and Mutations.

ATRX DAXX

2.00e-052156228062559
Pubmed

Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice.

APC SOAT1

2.00e-052156234914638
Pubmed

Expression and prognostic impact of alpha thalassemia/mental retardation X-linked and death domain-associated protein in human lung cancer.

ATRX DAXX

2.00e-052156231374064
Pubmed

DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.

ATRX DAXX

2.00e-052156238038252
Pubmed

Prognostic Significance of Altered ATRX/DAXX Gene in Pancreatic Neuroendocrine Tumors: A Meta-Analysis.

ATRX DAXX

2.00e-052156234220718
Pubmed

Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization.

ATRX DAXX

2.00e-052156230335163
Pubmed

Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.

CACNA1D CACNA1E

2.00e-05215628071363
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

2.00e-052156210070062
Pubmed

Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness.

CACNA1D OTOF

2.00e-052156233036242
Pubmed

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

CACNA1B CACNA1E

2.00e-052156212074836
Pubmed

SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.

SFPQ C9orf72

2.00e-052156233495278
Pubmed

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease.

CACNA1D ANK2

2.00e-052156218832177
Pubmed

Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells.

CACNA1D OTOF

2.00e-052156228193694
Pubmed

ATRX-DAXX Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.

ATRX DAXX

2.00e-052156231361513
Cytoband1q21.1

NBPF8 NBPF11 NBPF9 NBPF10 NBPF14

2.35e-066215651q21.1
GeneFamilyNeuroblastoma breakpoint family

NBPF3 NBPF8 NBPF12 NBPF26 NBPF11 NBPF1 NBPF19 NBPF9 NBPF10 NBPF14

7.76e-172311510662
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA1D CACNA1E

5.86e-04261153253
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CUL1 STRN3 ATRX BMP2K PODXL U2SURP WRN APC SRPK2 TMEM87A SETD2 BBX WDHD1 SACS BAZ1A GIGYF2 SPEN ZBTB18 NBPF14 ACBD3 PHIP KIF11

6.52e-0985615422M4500
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

CUL1 ATRX BBX WDHD1 SACS BAZ1A METTL18 SPEN PHIP KIF11 DOP1A

1.73e-0630015411M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CUL1 STRN3 ATRX U2SURP WRN SRPK2 SETD2 BBX BAZ1A GIGYF2 SPEN PHIP KIF11

4.04e-0646615413M13522
CoexpressionMURARO_PANCREAS_BETA_CELL

TANC2 PRUNE2 CACNA1D MIA3 ATRX U2SURP APC RNF187 BLOC1S2 ASAP1 KMT2C BBX ATP6V1D GIGYF2 RAB15 TSHZ1 RERE PRRC2B

1.20e-0594615418M39169
CoexpressionGSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP

MYT1L MIA3 BMP2K PLA2G4A ANKRD40 ZBTB18 PRRC2B DRC3

2.26e-051971548M5363
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

APC FRY SACS BAZ1A SNX10 SLC24A1 ZBTB18 PRRC2B

2.52e-052001548M4456
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PRUNE2 SOX11 EVC2 ANK2 P4HA3 PIEZO2 EIF3B SLC24A1

3.36e-0719015489ce301841ce9486701fa28eb2a9929e35d476878
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYT1L CACNA1B CACNA1E SRPK2 GRM1 SPHKAP RAB15 SNCB

3.64e-0719215484c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPAG1 SYNE1 SPEF2 ARMC2 CLMN CC2D2A CFAP74 DRC3

4.43e-07197154871fea4aa6ce96c7693fa94792d08770622873850
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

MYT1L ANK2 ATRX APC ARHGEF12 TRPM3 ZBTB18 DYNC1I2

4.78e-0719915481b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

MYT1L ANK2 ATRX APC ARHGEF12 TRPM3 ZBTB18 DYNC1I2

4.78e-0719915484bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 SFPQ ATRX KMT2C SETD2 APOL6 NUB1 PHIP

4.96e-07200154812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SPEF2 AK9 ARMC2 WDR93 CFAP74 DRC3

2.08e-06169154714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SOX11 ANK2 PODXL FRY PIEZO2 KDR SLC24A1

3.04e-06179154799777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P4HA3 ZFPM2 ASAP1 PIEZO2 KDR SNCB SLC24A1

3.40e-06182154753c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BDP1 SPEF2 NBPF26 PRR12 PLA2G4A C9orf72 CEP19

3.78e-0618515471b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BDP1 SPEF2 NBPF26 PRR12 PLA2G4A C9orf72 CEP19

3.78e-06185154702cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D NBPF26 ZFPM2 PRR12 PLA2G4A TNNT3 CEP19

3.92e-0618615471bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P4HA3 ZFPM2 ASAP1 PIEZO2 KDR SNCB SLC24A1

3.92e-06186154740070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D NBPF26 ZFPM2 PRR12 PLA2G4A TNNT3 CEP19

3.92e-06186154759db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFPQ SPEF2 APC MAGI3 BAZ1A SNX10 SOAT1

4.06e-061871547b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

ANK2 FSD2 SLC5A1 FRY GALNT17 KLHL7 SPHKAP

4.36e-0618915479c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES PODXL SYNE1 ARHGEF12 ZFPM2 ZBTB46 KDR

4.51e-0619015470e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

4.51e-0619015473a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES PODXL SYNE1 ARHGEF12 ZFPM2 ZBTB46 KDR

4.67e-061911547f229abf69a1217194f74b0502486907e07dba989
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

4.67e-0619115476688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

4.83e-06192154799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 ASAP1 NBPF19 KMT2C RERE NBPF14 EXOC4

5.00e-061931547779276e775cb2492e8dd36436295a536084a6415
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PODXL P4HA3 ASAP1 PIEZO2 PPM1F KDR SLC24A1

5.00e-061931547bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 SYNE1 SPEF2 AK9 CFAP74 DRC3

5.17e-0619415474a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D MIA3 ATRX KMT2C SPHKAP TSHZ1 RERE

5.35e-0619515473e519cffa6144a62b06124642a14c9ff39b76554
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 SPEF2 ARMC2 CLMN CC2D2A CFAP74 DRC3

5.35e-0619515473486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D MIA3 ATRX KMT2C SPHKAP TSHZ1 RERE

5.35e-0619515477796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

5.53e-0619615477d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 SPEF2 AK9 ARMC2 CC2D2A CFAP74 DRC3

5.72e-0619715476865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 SYNE1 SPEF2 CLMN CC2D2A DRC3

5.72e-06197154791637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SPEF2 AK9 ARMC2 WDR93 CFAP74 DRC3

5.72e-06197154774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL SYNE1 ASAP1 ZBTB46 PIEZO2 PPM1F KDR

5.91e-06198154731ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 SPEF2 AK9 CLMN CC2D2A CFAP74 DRC3

5.91e-061981547ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

5.91e-06198154726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

5.91e-0619815478f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PODXL SYNE1 P4HA3 ASAP1 PIEZO2 KDR SLC24A1

5.91e-06198154799d6a64f3410dae3019161feef20a8f06081a24b
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

BMP2K SYNE1 NBPF26 NBPF19 TRPM3 SPON1 NBPF10

6.31e-062001547d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

BMP2K SYNE1 NBPF26 NBPF19 TRPM3 SPON1 NBPF10

6.31e-062001547f861509b54185d89931db64da1b9d81986cc7938
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MYT1L CACNA1B BDP1 CACNA1D SYNE1 FRY GALNT17

6.31e-06200154748d801219bc771d6c7e151dc88ca4c179988de85
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

SYNE1 SPEF2 AK9 CLMN CC2D2A TNNT3 DRC3

6.31e-0620015473305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

BMP2K SYNE1 NBPF26 NBPF19 TRPM3 SPON1 NBPF10

6.31e-06200154716f468217427921fa18c6d078ffa990eb019b257
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 SYNE1 ZFPM2 GHR ESYT2 SPHKAP TSHZ1

6.31e-06200154702cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

BMP2K SYNE1 NBPF26 NBPF19 TRPM3 SPON1 NBPF10

6.31e-0620015470442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

BMP2K SYNE1 NBPF26 NBPF19 TRPM3 SPON1 NBPF10

6.31e-06200154701819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell(04)_Pre-ciliated-(4)_1wkpi|(04)_Pre-ciliated / shred by cell type and Timepoint

MYT1L CACNA1E P4HA3 KDR SNCB

1.45e-05891545846c2fec66981bf41be64a2e1812ec1b1b833961
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1E ZNF710 WDHD1 FIP1L1 KDR C9orf72

1.50e-0515215460652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 CACNA1B KMT2C FRY CLMN PLA2G4A

2.64e-0516815468072d0496b7b730c4601009eaa69ec5366d26d73
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D CACNA1E SPEF2 SPON1 SNCB SLC24A1

2.91e-05171154620ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D MAGI3 TRPM3 SPON1 APOL6 EXOC4

3.53e-051771546b7fee75de7e96924af488a5baa2334711889ae7c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES SFPQ ATRX SYNE1 TMEM87A KDR

3.65e-05178154601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PODXL ZFPM2 ASAP1 PIEZO2 KDR SLC24A1

3.65e-051781546ad3de3e03a401dac64431a541899445262246347
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K P4HA3 ZFPM2 ASAP1 PIEZO2 KDR

4.13e-05182154641b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K P4HA3 ZFPM2 ASAP1 PIEZO2 KDR

4.13e-0518215465e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K P4HA3 ZFPM2 ASAP1 PIEZO2 KDR

4.13e-051821546b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

ANK2 P4HA3 ZFPM2 GHR TSHZ1 TNNT3

4.25e-051831546de08f9ea02b7244d5a8788064631d10f06565337
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 ABCA13 GRM1 DNAH1 PIEZO2 TRPM3

4.39e-0518415462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GHR NBPF19 CLMN SPON1 NBPF10 NBPF14

4.39e-051841546658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 ABCA13 GRM1 DNAH1 PIEZO2 TRPM3

4.39e-051841546ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 ABCA13 GRM1 DNAH1 PIEZO2 TRPM3

4.39e-0518415462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L PRUNE2 GRM1 SPHKAP SNCB ZBTB18

4.39e-0518415467d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

NES PODXL SYNE1 ARHGEF12 ZFPM2 KDR

4.52e-051851546a28187c2fd23564314b35759479ff2ca21f61485
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ATRX APC ARHGEF12 OSBPL11 GIGYF2 TAF1

4.66e-05186154603db813598b67b1e08f759758a1c2023396921fa
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZFPM2 ASAP1 PIEZO2 SPHKAP KDR SLC24A1

4.66e-05186154620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PODXL ZBTB46 PPM1F KDR TDRD6 TNNT3

4.66e-051861546a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CACNA1D ZFPM2 GHR PIEZO2 GALNT17 SPON1

4.80e-05187154692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1D GHR PIEZO2 GALNT17 SPON1 FHOD1

4.80e-051871546e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

NES PODXL SYNE1 ARHGEF12 ZFPM2 KDR

4.80e-05187154654d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ABCA13 SPEF2 AK9 ARMC2 CFAP74 DRC3

5.09e-0518915463e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX11 ZFPM2 ASAP1 PIEZO2 SPHKAP KDR

5.24e-051901546876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ANK2 FSD2 SLC5A1 GALNT17 KLHL7 SPHKAP

5.24e-051901546de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES PODXL SYNE1 ZFPM2 ZBTB46 KDR

5.24e-0519015460a351609a72fd638c84b2435782e312ee6a33aac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX11 ZFPM2 ASAP1 PIEZO2 SPHKAP KDR

5.24e-051901546be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX11 ZFPM2 ASAP1 PIEZO2 SPHKAP KDR

5.24e-05190154609a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

ANK2 FSD2 ZFPM2 GALNT17 KLHL7 SPHKAP

5.40e-05191154625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CACNA1B SRPK2 GRM1 RNF187 SPHKAP SNCB

5.40e-0519115465d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CACNA1B SRPK2 GRM1 RNF187 SPHKAP SNCB

5.40e-05191154673dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17

5.55e-0519215468d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

ANK2 FSD2 FRY GALNT17 KLHL7 SPHKAP

5.55e-051921546ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ANK2 ZFPM2 GHR PIEZO2 GALNT17 SPON1

5.55e-051921546a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL ASAP1 ZBTB46 PIEZO2 PPM1F KDR

5.55e-051921546c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ABCA13 SPEF2 AK9 ARMC2 CFAP74 DRC3

5.72e-0519315460e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L CACNA1B CACNA1E RTL1 SPHKAP RAB15

5.72e-051931546461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L CACNA1B CACNA1E RTL1 SPHKAP RAB15

5.72e-0519315460dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 SPEF2 ARMC2 CLMN CFAP74 DRC3

5.72e-051931546ea345d34440b25f65358a53dc72831998d1c3620
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SYNE1 SPEF2 AK9 ARMC2 CFAP74 DRC3

5.72e-051931546ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL SYNE1 ASAP1 ZBTB46 PIEZO2 KDR

5.72e-051931546456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 SPEF2 ARL3 CLMN DRC3

5.88e-0519415463cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BDP1 SOX11 SFPQ ATRX ASAP1 KDR

5.88e-051941546e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL ARHGEF12 GHR PIEZO2 PPM1F KDR

5.88e-051941546f159ef8541d75a4e98468947f231bb463bec922c
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 SYNE1 SPEF2 AK9 CC2D2A DRC3

5.88e-051941546b4ce60c06568123008b1081d644733cb91c28f51
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1D ANK2 ZFPM2 GHR PIEZO2 GALNT17

5.88e-051941546439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D ANK2 SYNE1 PIEZO2 GALNT17 SPON1

5.88e-05194154660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

CUL1 SKI KMT2C OTOF APOL6 DSE

5.88e-051941546d1366b169d14011194e61d16b6b0953349febc78
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1D ZFPM2 PIEZO2 GALNT17 SPON1 FHOD1

5.88e-05194154635f132cc38ac133be01834ed0946188aa0757eb4
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D ANK2 SYNE1 PIEZO2 GALNT17 SPON1

5.88e-0519415466e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 SYNE1 SPEF2 AK9 CC2D2A DRC3

5.88e-0519415467a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL ASAP1 ZBTB46 PIEZO2 PPM1F KDR

5.88e-051941546e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ABCA13 SPEF2 ARL3 CLMN DRC3

6.05e-051951546d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL SYNE1 ASAP1 ZBTB46 PIEZO2 KDR

6.05e-05195154623ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MIA3 ANK2 SPHKAP TSHZ1 PRRC2B

6.05e-051951546bd8e24dd598990204998d1dd853ba7a53dc0107e
DrugmAHP

CACNA1B CACNA1D CACNA1E NES GRM1

8.34e-07271505CID000220531
Druggadolinium

CACNA1B CACNA1D CACNA1E GRM1 GHR TMX1 TRPM3 SACS KDR RERE

8.40e-0719915010CID000023982
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TCF3 APC GHR WDHD1 BAZ1A FHOD1 OSBPL11 FIP1L1 PRRC2B

5.11e-0619115091059_DN
Drugionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA

NES U2SURP ASAP1 TMX1 WDHD1 OSBPL11 SPEN SOAT1 PRRC2B

6.57e-061971509882_DN
DrugPesticides

NBPF8 CACNA1D NBPF12 NBPF11 NBPF1 NBPF9 NBPF10 NBPF14

7.03e-061501508ctd:D010575
DiseaseIntellectual Disability

MYT1L TANC2 CACNA1B CACNA1E SYNE1 APC PRR12 KMT2C SETD2 FRY TRPM3 SACS TAF1 PHIP DYNC1I2

4.76e-0944714215C3714756
DiseaseNeurodevelopmental Disorders

MYT1L TANC2 ANK2 KMT2C SETD2 GIGYF2

6.04e-06931426C1535926
DiseaseColorectal Carcinoma

TCF3 EVC2 ANK2 ABCA13 SYNE1 WRN APC GRM1 KMT2C SACS PPM1F KDR PHIP EXOC4

7.96e-0670214214C0009402
DiseaseGlobal developmental delay

CACNA1B CACNA1E PRR12 TRPM3 TAF1 ZBTB18

4.64e-051331426C0557874
DiseasePancreatic Endocrine Carcinoma

ATRX DAXX

6.88e-0531422C1328479
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1B CACNA1E

6.88e-0531422DOID:0111181 (implicated_via_orthology)
DiseaseAdenoid Cystic Carcinoma

SOX11 ATRX IRX4 KMT2C SETD2

1.25e-041001425C0010606
Diseasemigraine (implicated_via_orthology)

CACNA1B CACNA1E

1.37e-0441422DOID:6364 (implicated_via_orthology)
Diseaseimmature platelet count

ZFPM2 ASAP1 ESYT2 SETD2 TRPM3

1.65e-041061425EFO_0803544
Diseaseatrophic macular degeneration, age-related macular degeneration, wet macular degeneration

SPEF2 SRPK2 NPLOC4 TRPM3

2.03e-04601424EFO_0001365, EFO_0004683, EFO_1001492
DiseaseGlioblastoma Multiforme

CDC42BPG ATRX APC SRPK2 TAF1L

2.05e-041111425C1621958
Diseasesarcoma (is_marker_for)

ATRX KDR

2.28e-0451422DOID:1115 (is_marker_for)
DiseaseChromosome 1p36 Deletion Syndrome

SKI RERE

2.28e-0451422C1842870
DiseaseARTHROGRYPOSIS, DISTAL, TYPE 2B

PIEZO2 TNNT3

3.41e-0461422C1834523
Diseasemean platelet volume

STRN3 DIS3L U2SURP ZFPM2 ASAP1 ZNF710 CCDC43 ESYT2 SETD2 FRY BBX TRPM3 PHIP DSE

4.23e-04102014214EFO_0004584
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1B CACNA1E

4.75e-0471422DOID:0050951 (implicated_via_orthology)
DiseaseKartagener Syndrome

SPAG1 SPEF2 DNAH1

6.38e-04351423C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

SPAG1 SPEF2 DNAH1

6.38e-04351423C4551906
DiseasePolynesian Bronchiectasis

SPAG1 SPEF2 DNAH1

6.38e-04351423C4317124
DiseaseDistal arthrogryposis

PIEZO2 TNNT3

8.10e-0491422cv:C0265213
Diseasenasopharynx carcinoma (is_marker_for)

KMT2C KDR SPEN

1.17e-03431423DOID:9261 (is_marker_for)
Diseasechronotype measurement

TANC2 ANK2 PODXL YIPF4 DDI2 DNAH1 WDHD1 TSHZ1 RERE SOAT1 IP6K2 EXOC4

1.18e-0388214212EFO_0008328
Diseasemeningitis

CACNA1E RERE

1.23e-03111422MONDO_0021108
DiseaseNeuroendocrine Tumors

ATRX DAXX

1.23e-03111422C0206754
Diseasereaction time measurement

PODXL APC SETD2 PRDM11 SPON1 CC2D2A GIGYF2 TSHZ1 RERE DYNC1I2

1.36e-0365814210EFO_0008393
DiseaseCrohn's disease

CUL1 SLC52A1 ANK2 MAGI3 KSR1 TRPM3 PLA2G4A HSP90AA4P

1.37e-034411428EFO_0000384
DiseasePancreatic Neoplasm

ATRX APC DAXX KDR

1.41e-031001424C0030297
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

SYNE1 ZFPM2 RERE HSP90AA4P

1.46e-031011424EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
DiseaseSalivary Gland Neoplasms

SOX11 IRX4 SPEN

1.52e-03471423C0036095
DiseasePrimary Ciliary Dyskinesia

SPAG1 SPEF2 DNAH1

1.52e-03471423C4551720
DiseaseMalignant neoplasm of pancreas

ATRX APC DAXX KDR

1.52e-031021424C0346647
Diseaseforced expiratory volume

CACNA1D BMP2K PODXL SYNE1 AK9 SKI ARMC2 PRDM11 KDR PHIP PRRC2B

1.56e-0378914211EFO_0004314
Diseaseschizophrenia, anorexia nervosa

SRPK2 GIGYF2 RERE

1.61e-03481423MONDO_0005090, MONDO_0005351
DiseaseRetinitis Pigmentosa

IRX5 CDHR1 ARL3 KLHL7

1.63e-031041424C0035334
Diseasecognitive function measurement, self reported educational attainment

TANC2 CACNA1E WRN SRPK2 PRR12 IP6K2 EXOC4

1.71e-033551427EFO_0004784, EFO_0008354
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

TANC2 TCF3 GIGYF2

1.71e-03491423DOID:0060037 (implicated_via_orthology)
Diseaseimmature platelet fraction

ZFPM2 ASAP1 ESYT2 TRPM3

2.28e-031141424EFO_0009187
Diseaseglycerol-3-phosphate measurement

NBPF3 ACBD3

2.32e-03151422EFO_0010488
DiseaseNasal Cavity Polyp

MIA3 SPEF2 GIGYF2

2.38e-03551423EFO_1000391
Diseasevascular endothelial growth factor measurement

EVC2 ZFPM2 ZNF710

2.51e-03561423EFO_0004762
Diseasecathepsin L1 measurement

GRM1 C9orf72

2.64e-03161422EFO_0010619
Diseasecolorectal cancer (is_implicated_in)

TCF3 APC SETD2 KDR

2.83e-031211424DOID:9256 (is_implicated_in)
Diseasemean arterial pressure

CACNA1D PODXL ARHGEF12 ARL3 CLCN6 RERE TNNT3 PHIP

2.95e-034991428EFO_0006340
Diseaseautoimmune thyroid disease

SPEF2 MAGI3 TIMMDC1 RERE

3.27e-031261424EFO_0006812
DiseaseMalignant Neoplasms

WRN APC SETD2 KDR

3.46e-031281424C0006826
Diseaseplatelet component distribution width

PRUNE2 BMP2K SYNE1 U2SURP SKI ZFPM2 ASAP1 ZNF710 SETD2 TRPM3

3.66e-0375514210EFO_0007984
Diseaseurate measurement

CDC42BPG HSP90B2P SLC52A1 PODXL U2SURP SNX17 SKI SLC5A1 DNAH1 PLA2G4A PRRC2B

4.10e-0389514211EFO_0004531
DiseaseDeaf Mutism

CACNA1D OTOF

4.13e-03201422C4082305
DiseaseDeafness, Acquired

CACNA1D OTOF

4.13e-03201422C0751068
DiseaseHearing Loss, Extreme

CACNA1D OTOF

4.13e-03201422C0086395
DiseaseComplete Hearing Loss

CACNA1D OTOF

4.13e-03201422C0581883
DiseaseBilateral Deafness

CACNA1D OTOF

4.13e-03201422C3665473
DiseasePrelingual Deafness

CACNA1D OTOF

4.13e-03201422C0011052
Diseasesusceptibility to mononucleosis measurement

MYT1L CUL1 PRDM11

4.53e-03691423EFO_0008403

Protein segments in the cluster

PeptideGeneStartEntry
AEEAKEPAEADITEL

BLOC1S2

26

Q6QNY1
NLPSEKEDTEVELDE

ERICH6B

26

Q5W0A0
GQELEIELFDEDPDK

ESYT2

451

A0FGR8
PEVIDATEEIDKDLE

BDP1

916

A6H8Y1
VKIEAIDEDAEEPNN

CDHR1

591

Q96JP9
DDVSEEELLGDVLKD

EIF3B

161

P55884
EDEEEDIDKVQLLGA

BBX

46

Q8WY36
ASPLKEAEIREDEEE

CACNA1E

1096

Q15878
ETTIDPEEDLNKLDD

CEP19

96

Q96LK0
EDVELQDGDLSPEEK

APOL6

26

Q9BWW8
PKADLQEEDAEIEVD

ARMC2

251

Q8NEN0
LKEQETEEEIPDDAQ

EIF4EBP3

81

O60516
EETGQELAELLEEEK

ARL3

101

P36405
ELLEDDKEKFNIPED

ABCA13

3271

Q86UQ4
DIDPDEETIKIEDDS

DOP1A

1186

Q5JWR5
DDDDDDNLPQLKKES

ANKRD40

101

Q6AI12
AELEELEQEEPDKNL

CHMP4BP1

126

P59074
PKSSEEEEQDDEEVL

BMP2K

751

Q9NSY1
AEEDRNAEEKSPLDV

CACNA1B

401

Q00975
QEKELDLSELDDPDS

DAXX

206

Q9UER7
EPKEQEDLQENDEEG

DDX27

151

Q96GQ7
DTKDLTEALDEDADP

BAZ1A

501

Q9NRL2
EGDNDEEDPSKLKEE

ARHGEF12

1151

Q9NZN5
NELALAELEEEEGKP

RAB15

186

P59190
EEKELELSDLDDFDP

IRX4

251

P78413
EENIDLEKNDEDEPQ

IRX5

191

P78411
ELAPSKLEEEVDDVF

GRSF1

136

Q12849
QLAEKDEFDIPDLTD

CDC42BPG

1381

Q6DT37
EKVEQDLPAFEDLEG

P4HA3

121

Q7Z4N8
AVNEILEDIPEHEED

NUB1

571

Q9Y5A7
SKETVDDEADLLPDD

ANK2

3171

Q01484
TKDSLDDLFPNEEEE

KLC4

171

Q9NSK0
GILQEEEEEEKLDAL

CCDC43

46

Q96MW1
AEEKLSEEATEEPDA

CT47A1

216

Q5JQC4
DALEFADEEKESPVE

NOL9

476

Q5SY16
PLDNLTKDDLDEEED

PODXL

541

O00592
DKTVLDLAVVEEPDE

HSP90B2P

346

Q58FF3
GVEVKDLDDEDLENL

KMT2C

2706

Q8NEZ4
LPEEEEDEDKEAING

MAGI3

236

Q5TCQ9
EEEEEKGNEEPLSLD

SLC24A1

886

O60721
KEAAPDQEEEAEAER

HDGFL1

161

Q5TGJ6
PEVVLDSDAEDLEDL

IP6K2

341

Q9UHH9
ENNKEETIPDVDVEE

KIF11

966

P52732
QIKRPLEDAIEDEEE

ZFPM2

11

Q8WW38
AQPKEDEEEDDDVVA

DYNC1I2

166

Q13409
ADVDPKLLELTADEE

EID3

21

Q8N140
LKPILEESENEDEDG

PNMA6F

551

A0A0J9YX94
DDQPKADVLEAHEAE

KSR1

546

Q8IVT5
ELLEDPKAEVVDEIA

NPLOC4

286

Q8TAT6
KDLDENEVERPEEEN

FIP1L1

41

Q6UN15
PEEVDKESQRNLEEE

NES

906

P48681
KDDAPEAVTEEQAEL

EVC2

811

Q86UK5
QILAQKELPIDEDEE

DSE

841

Q9UL01
TLEDEENDVNEPDVK

METTL18

236

O95568
EKELEPEAAEEALEN

ACBD3

346

Q9H3P7
ELKDAEPDIIEQLVE

KLHL7

86

Q8IXQ5
DLESNVESEEENEKP

NOP14

381

P78316
KLSPENDEDEDEDVQ

NBPF1

161

Q3BBV0
QKLSPENDEDEDEDV

NBPF1

431

Q3BBV0
QKLSPENDDDEDEDV

NBPF3

216

Q9H094
ADDAQKDLDEALPAL

DNAH1

2906

Q9P2D7
QDIKEDLELDPEENS

EXOC4

261

Q96A65
ESDDEKPLDDETVNE

ATRX

91

P46100
DEHIASEEPAEKEDL

CLCN6

691

P51797
LPLLEKSQGEDVEDD

CC2D2A

1531

Q9P2K1
EPDDEEGLKHLEQQA

GIGYF2

481

Q6Y7W6
IELDIDEPDEKTEES

GHR

346

P10912
LEDENANVDEVELKP

CUL1

651

Q13616
LSVVDDIPEFKDLDE

DIS3L

601

Q8TF46
DDNSDEEELKVPLEE

GALNT17

191

Q6IS24
QEEIDESDDDLDDKP

ASAP1

711

Q9ULH1
FPDAEENKILKESDE

FRY

1546

Q5TBA9
SVTKEDLELPEDEEE

HSP90AA4P

251

Q58FG1
DPFDLEAQAKIEEDI

DDI2

196

Q5TDH0
KIVEGDLDEDLPNDL

DRC3

426

Q9H069
ENALKLEDGDIEEAP

FHOD1

331

Q9Y613
EEEEDLQAASKLTPD

GRM1

1126

Q13255
EDINKDKNLVPEDEA

SLC39A10

386

Q9ULF5
KDAEENEIEVEGLPL

SACS

3141

Q9NZJ4
DLQDDEPEETKREEE

CACNA1D

1661

Q01668
ELEKLDKEQEEEQPA

CFAP74

711

Q9C0B2
PEEIDIADTVLNDDD

C9orf72

196

Q96LT7
LPKVDDEEDEDLEIE

DHX8

426

Q14562
QEPSGIDLEEKEEVD

OTOF

1346

Q9HC10
EEDDDEEEKAPVTLL

PPM1F

106

P49593
LAREPEEINADDEIE

OSBPL11

336

Q9BXB4
PRETEEEKEIADFDI

PLA2G4A

656

P47712
DLADVFNPKEADDET

RTL1

561

A6NKG5
TDLKPEEVAQEAAEE

SNCB

91

Q16143
DIENILEDEFPKDEE

AK9

1231

Q5TCS8
DDDELQLQIKQEPDE

SOX11

231

P35716
NKIIVDDAEEADTEP

SPHKAP

1321

Q2M3C7
NDEEDALPVLQEEIK

SPEF2

616

Q9C093
DLTDDPDTEEALKEF

STRN3

291

Q13033
NVDDIVADLAPEEKD

SPON1

421

Q9HCB6
EEDEDQRNPAKESLE

SOAT1

21

P35610
LEKEPADKTDDDIEQ

RAPGEF6

256

Q8TEU7
PDDESKEFLELESIE

TDRD6

1841

O60522
IDINVDELDTPDEAD

PRUNE2

2831

Q8WUY3
QEAEKEEGLPEDELA

RNF187

191

Q5TA31
KSEPLDAAIIEEELD

SYNE1

8176

Q8NF91
KEDEENQEDFDELPL

MIA3

316

Q5JRA6
EKEDDDDALVPDSKQ

MIA3

411

Q5JRA6
KLSPENDEDEDEDVQ

NBPF8

126

Q3BBV2
IIPENESDDEEEEEK

NBPF8

491

Q3BBV2
KLSPENDEDEDEDVQ

NBPF9

161

P0DPF3
IIPENESDDEEEEEK

NBPF9

526

P0DPF3
KLSPENDEDEDEDVQ

NBPF10

161

Q6P3W6
IIPENESDDEEEEEK

NBPF10

526

Q6P3W6
KLSPENDEDEDEDVQ

NBPF11

161

Q86T75
IIPENESDDEEEEEK

NBPF11

526

Q86T75
KLSPENDEDEDEDVQ

NBPF12

161

Q5TAG4
QKLSPENDEDEDEDV

NBPF12

431

Q5TAG4
IIPENESDDEEEEEK

NBPF14

186

Q5TI25
DRIKKDQEEEEDQDP

NBPF19

1211

A0A087WUL8
IIPENESDDEEEEEK

NBPF26

186

B4DH59
KEAALEEAELESLDP

TAF1L

1641

Q8IZX4
DENLILEIPDEKEEA

TAF1

506

P21675
EVIPLNEALESAKDE

FSD2

201

A1L4K1
QLEDEEEEPSSFKAD

PRDM11

411

Q9NQV5
DAGADELEEVIKDDI

SETSIP

221

P0DME0
LQDELSDVIDIKDPD

SHQ1

161

Q6PI26
LDLPEKDEEEVERAQ

TANC2

1011

Q9HCD6
PQQHEEEDLDDDVIL

RNF216

51

Q9NWF9
LGLPTKEEEEDDENE

WRN

501

Q14191
VQIKEEALDDAEEPE

RERE

1091

Q9P2R6
FEADEDKADVPADIR

PRR12

1101

Q9ULL5
VAAPEEDKDSEAEVE

SKI

471

P12755
IIEEKETEDVPDDLD

U2SURP

681

O15042
PELDDNKAEEGDILA

APC

1711

P25054
PELEAEDIFDSDKEV

CLMN

291

Q96JQ2
KKDDEEEDPLDQLIS

COA4

16

Q9NYJ1
EQLDDEDGLPEKLAQ

SFPQ

451

P23246
DVLEAVAAKLDLPDD

SNX17

141

Q15036
PISSAEEFDDDEKIE

ZNF532

131

Q9HCE3
DEEEENEAKEPAETL

SPEN

1961

Q96T58
IDDPIDEEEEFEELK

PHIP

1746

Q8WWQ0
EEEEKEEEEALPLQE

SLC52A1

241

Q9NWF4
DEDEDDLLPPEQKAE

TCF3

531

P15923
REEEVDIDLDDPEIN

TRPM3

641

Q9HCF6
EDLDDDDPKFINVGE

WDHD1

41

O75717
EDEPENDAKKIEALL

TIMMDC1

256

Q9NPL8
PSDEDEGEDEKLNIL

ZBTB18

156

Q99592
TEDLSKVLDVEPDND

SPAG1

296

Q07617
KDEDDVDQELANIDP

SRPK2

361

P78362
EPANLLAEEKDEDLL

ATP6V1D

231

Q9Y5K8
EKDEELQDIQVEGEP

PIEZO2

626

Q9H5I5
LQDIQVEGEPKEEEE

PIEZO2

631

Q9H5I5
LEEPAEEEVLEVEAA

ZNF710

76

Q8N1W2
PTAEKDEDEENDASL

PRRC2B

981

Q5JSZ5
KEDLDQLENVPVEEE

SETD2

1906

Q9BYW2
FPEEDEEGKKENDID

SNX10

156

Q9Y5X0
EAEKEEREEDEVFPQ

TTC36

31

A6NLP5
DDEQDHVLVDPDEEL

WDR93

36

Q6P2C0
VQEDTAEEDAEEEKP

TNNT3

36

P45378
VEDDDPEDNKPLLEE

YIPF4

66

Q9BSR8
KSLSDVEEEEAPEDL

KDR

981

P35968
IDLDAEEENIQEGPK

SLC5A1

571

P13866
PLKKVEEEQEADEED

TMX1

231

Q9H3N1
VPEEELKAAEIDEEH

TSHZ1

16

Q6ZSZ6
PLVAVFDDLDIEADE

USP33

161

Q8TEY7
APEDALLADDKDEED

ZBTB46

556

Q86UZ6
FSPLSEEEEEDEQKE

TMEM87A

471

Q8NBN3
IDEDESKDITPEDLD

MYT1L

831

Q9UL68