Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

1.53e-0651083GO:0030156
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

MAP4K3 PSKH1 PAK5 DGKB MAP3K4 ITPKB PIK3C2B MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

6.34e-0670910815GO:0016773
GeneOntologyMolecularFunctionkinase activity

MAP4K3 PSKH1 PAK5 DGKB MAP3K4 ITPKB PIK3C2B MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

1.54e-0576410815GO:0016301
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

MAP4K3 PSKH1 PAK5 DGKB MAP3K4 ITPKB PIK3C2B MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10 PARP12

4.34e-0593810816GO:0016772
GeneOntologyMolecularFunctionJUN kinase activity

MAPK8 MAPK10

8.66e-0531082GO:0004705
GeneOntologyMolecularFunctionprotein kinase activity

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

9.79e-0560010812GO:0004672
GeneOntologyMolecularFunctionprotein serine kinase activity

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10 ULK2

1.58e-043631089GO:0106310
GeneOntologyMolecularFunctionMAP kinase kinase kinase kinase activity

MAP4K3 MAP4K5

4.29e-0461082GO:0008349
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10 ULK2

7.09e-044461089GO:0004674
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT3P GGTLC3

1.02e-0391082GO:0036374
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1B CACNA1E

1.02e-0391082GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1B CACNA1E

1.02e-0391082GO:0099626
GeneOntologyMolecularFunctionprotein transporter activity

ABCA1 RHBDF2 PEX12

1.52e-03421083GO:0140318
MousePhenoabnormal sperm number

ABCA1 SETX RHBDF2 CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

3.98e-066248415MP:0002673
MousePhenoectopic manchette

IQCN RIMBP3 RIMBP3C RIMBP3B

4.39e-0619844MP:0009377
MousePhenoabnormal acrosome morphology

SETX IQCN RIMBP3 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

4.92e-06159848MP:0008898
MousePhenodecreased male germ cell number

ABCA1 SETX RHBDF2 CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

5.42e-066408415MP:0004901
MousePhenoabnormal manchette morphology

IQCN RIMBP3 DCAF17 RIMBP3C RIMBP3B

7.03e-0645845MP:0009376
MousePhenoabnormal male germ cell morphology

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 IHO1 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.12e-058598417MP:0006362
MousePhenodecreased germ cell number

ABCA1 SETX RHBDF2 CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.27e-056878415MP:0002209
MousePhenoabnormal gametes

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.47e-057858416MP:0001124
MousePhenoabnormal spermatogenesis

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 IHO1 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

2.37e-059108417MP:0001156
MousePhenoabnormal germ cell morphology

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 IHO1 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

3.88e-059468417MP:0002208
MousePhenoabnormal foam cell morphology

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 IHO1 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

4.31e-059548417MP:0009840
MousePhenooligozoospermia

ABCA1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B

9.83e-053848410MP:0002687
MousePhenoabnormal long-term spatial reference memory

CACNA1B NEXMIF DGKB SIPA1L2

1.04e-0441844MP:0008432
MousePhenodetached acrosome

RIMBP3 DCAF17 RIMBP3C RIMBP3B

1.37e-0444844MP:0009231
MousePhenoteratozoospermia

SETX IQCN CNBD2 RIMBP3 FSIP2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.62e-044088410MP:0005578
MousePhenoabnormal sperm head morphology

SETX IQCN RIMBP3 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.70e-04261848MP:0009230
MousePhenoabnormal gametogenesis

ABCA1 SETX RHBDF2 IQCN CNBD2 TDRD1 GGT3P MAP3K4 IHO1 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

1.77e-0410708417MP:0001929
MousePhenoinfertility

ABCA1 SETX NEXMIF SRY IQCN CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3 PARP12

2.00e-0411888418MP:0001924
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B

2.57e-0421843MP:0008893
MousePhenoovotestis

SRY MAP3K4

3.53e-045842MP:0002996
MousePhenoabnormal stomach non-glandular epithelium morphology

KEAP1 TP63

3.53e-045842MP:0000472
MousePhenomale infertility

SETX NEXMIF IQCN CNBD2 TDRD1 GGT3P MAP3K4 RIMBP3 FSIP2 CCNE2 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

4.51e-049448415MP:0001925
MousePhenoabnormal spermiogenesis

SETX RIMBP3 DNAH17 DCAF17 RIMBP3C RIMBP3B JAM3

5.51e-04237847MP:0001932
DomainPROTEIN_KINASE_ATP

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

1.15e-0545910612PS00107
DomainKinase-like_dom

MAP4K3 PSKH1 PAK5 MAP3K4 PIK3C2B MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

1.21e-0554210613IPR011009
DomainProt_kinase_dom

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

2.15e-0548910612IPR000719
DomainPROTEIN_KINASE_DOM

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2 MUSK EPHA10

2.32e-0549310612PS50011
DomainS_TKc

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2

3.77e-0535910610SM00220
DomainPkinase

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 PEAK1 MAPK8 MAPK10 ULK2

6.21e-0538110610PF00069
DomainSH3_2

MPP3 RIMBP3 MAP3K9 RIMBP3C RIMBP3B

1.29e-04861065PF07653
DomainSH3_2

MPP3 RIMBP3 MAP3K9 RIMBP3C RIMBP3B

1.29e-04861065IPR011511
DomainMAPKKKK

MAP4K3 MAP4K5

1.90e-0441062IPR021160
DomainSer/Thr_kinase_AS

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10 ULK2

1.98e-043571069IPR008271
DomainPROTEIN_KINASE_ST

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10 ULK2

2.20e-043621069PS00108
DomainMAPK_JNK

MAPK8 MAPK10

3.16e-0451062IPR008351
DomainCa_chan_IQ

CACNA1B CACNA1E

6.58e-0471062SM01062
DomainCa_chan_IQ

CACNA1B CACNA1E

6.58e-0471062PF08763
DomainVDCC_a1su_IQ

CACNA1B CACNA1E

6.58e-0471062IPR014873
DomainGPHH

CACNA1B CACNA1E

6.58e-0471062PF16905
DomainGPHH_dom

CACNA1B CACNA1E

6.58e-0471062IPR031649
DomainFN3

RIMBP3 ASTN1 RIMBP3C RIMBP3B MDGA1 EPHA10

9.57e-041991066PS50853
DomainSH3_9

RIMBP3 MAP3K9 RIMBP3C RIMBP3B

1.01e-03781064PF14604
DomainFN3_dom

RIMBP3 ASTN1 RIMBP3C RIMBP3B MDGA1 EPHA10

1.23e-032091066IPR003961
DomainVDCCAlpha1

CACNA1B CACNA1E

1.39e-03101062IPR002077
DomainProtein_kinase_ATP_BS

MAP4K3 PSKH1 PAK5 MAP3K4 MAP4K5 MAP3K9 ULK2 MUSK

1.43e-033791068IPR017441
DomainSH3

MPP3 RIMBP3 MAP3K9 RIMBP3C RIMBP3B TP53BP2

1.46e-032161066SM00326
DomainSH3

MPP3 RIMBP3 MAP3K9 RIMBP3C RIMBP3B TP53BP2

1.46e-032161066PS50002
DomainSH3_domain

MPP3 RIMBP3 MAP3K9 RIMBP3C RIMBP3B TP53BP2

1.60e-032201066IPR001452
DomainMAPK

MAPK8 MAPK10

2.03e-03121062PS01351
DomainMAP_kinase_CS

MAPK8 MAPK10

2.03e-03121062IPR003527
DomainIg-like_fold

MYCBP2 LILRB2 RIMBP3 IGSF10 ASTN1 RIMBP3C RIMBP3B MDGA1 MUSK EPHA10 JAM3

2.23e-0370610611IPR013783
DomainCNH

MAP4K3 MAP4K5

2.78e-03141062SM00036
DomainCNH

MAP4K3 MAP4K5

3.19e-03151062PF00780
DomainCNH

MAP4K3 MAP4K5

3.19e-03151062PS50219
DomainCNH_dom

MAP4K3 MAP4K5

3.19e-03151062IPR001180
DomainSushi

CSMD2 CR1 C1S

3.21e-03521063PF00084
DomainCCP

CSMD2 CR1 C1S

3.57e-03541063SM00032
DomainEGF-like_CS

LAMC2 ITGB6 FBN1 C1S ASTN1 EPHA10

3.74e-032611066IPR013032
DomainSUSHI

CSMD2 CR1 C1S

3.96e-03561063PS50923
DomainEGF_2

LAMC2 ITGB6 FBN1 C1S ASTN1 EPHA10

4.03e-032651066PS01186
DomainFN3

ASTN1 RIMBP3C RIMBP3B MDGA1 EPHA10

4.09e-031851065SM00060
DomainSushi_SCR_CCP_dom

CSMD2 CR1 C1S

4.16e-03571063IPR000436
Domain-

MYCBP2 RIMBP3 IGSF10 ASTN1 RIMBP3C RIMBP3B MDGA1 MUSK EPHA10 JAM3

4.44e-03663106102.60.40.10
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

MAP4K3 PAK5 ITGB6 MAP4K5 MAPK8 MAPK10

1.42e-0747736M39829
PathwayBIOCARTA_MAPK_PATHWAY

MAP4K3 MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10

3.74e-0681736M13863
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

MAP4K3 CBLB MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10

5.24e-06132737M39338
PathwayWP_INSULIN_SIGNALING

MAP4K3 CBLB MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10

1.85e-05160737MM15956
PathwayWP_INSULIN_SIGNALING

MAP4K3 CBLB MAP3K4 MAP4K5 MAP3K9 MAPK8 MAPK10

1.85e-05160737M39482
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAP3K9 MAPK8 MAPK10

2.83e-0512733M47929
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAP3K4 MAP3K9 MAPK8 MAPK10

3.44e-0536734M39908
PathwayBIOCARTA_MAPK_PATHWAY

MAP4K3 MAP3K4 MAP4K5 MAPK8 MAPK10

4.50e-0576735MM1433
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1B CACNA1E MAPK8 MAPK10

9.97e-0547734M19708
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP

PTPRR MAPK8 MAPK10

1.43e-0420733M47928
PathwayKEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

2.62e-045732M47570
PathwayKEGG_MEDICUS_ENV_FACTOR_PARAQUAT_TO_FAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

2.62e-045732M49021
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

2.62e-045732M49005
PathwayWP_MAPK_SIGNALING

CACNA1B CACNA1E MAP4K3 MAP3K4 PTPRR MAPK8 MAPK10

2.77e-04246737M39597
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

3.91e-046732M47680
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

3.91e-046732M47698
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY

MAPK8 MAPK10

3.91e-046732M47712
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA1B CACNA1E MAP4K3 MAP3K4 PTPRR MAPK8 MAPK10

4.54e-04267737M10792
PathwayREACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS

TP63 MAPK8 TP53BP2

4.89e-0430733M17814
PathwayPID_CD40_PATHWAY

CBLB MAPK8 MAPK10

5.40e-0431733M45
PathwayKEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

5.46e-047732M47697
PathwayKEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

5.46e-047732M47711
PathwayBIOCARTA_AGR_PATHWAY

PAK5 MAPK8 MUSK

6.50e-0433733M6220
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY

MAPK8 MAPK10

7.26e-048732M47814
PathwayREACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA

TP63 TP53BP2

9.30e-049732M26946
PathwayKEGG_ERBB_SIGNALING_PATHWAY

PAK5 CBLB MAPK8 MAPK10

1.07e-0387734M12467
PathwayWP_OXIDATIVE_DAMAGE_RESPONSE

MAP3K9 C1S MAPK10

1.15e-0340733M39340
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK8 MAPK10

1.16e-0310732MM15135
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK8 MAPK10

1.16e-0310732M13962
PathwayWP_ERBB_SIGNALING

PAK5 CBLB MAPK8 MAPK10

1.31e-0392734M39715
PathwayWP_OXIDATIVE_DAMAGE_RESPONSE

MAP3K9 C1S MAPK10

1.32e-0342733MM15945
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1B CACNA1E

1.41e-0311732MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1B CACNA1E

1.41e-0311732M26913
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1B CACNA1E

1.41e-0311732M47958
PathwayWP_MAPK_SIGNALING_PATHWAY

MAP4K3 MAP3K4 PTPRR MAPK8 MAPK10

1.43e-03160735MM15990
PathwayWP_EGFEGFR_SIGNALING

CBLB MAP3K4 PIK3C2B PTPRR MAPK8

1.51e-03162735M39334
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_DEATH_RECEPTORS_AND_LIGANDS

TP63 TP53BP2

1.69e-0312732M27631
PathwayWP_PLEURAL_MESOTHELIOMA

MAP4K3 PAK5 LAMC2 MAP3K4 MAP3K9 MAPK8 MAPK10 ULK2

1.90e-03439738M42563
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SETX MYCBP2 BCAS3 PAK5 FAM98A PITPNC1 ITPKB FSIP2 NHSL1 FAM117A PIK3C2B MAP3K9 PEAK1 SIPA1L2 MUSK TP53BP2

1.58e-088611111636931259
Pubmed

A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.

MAPKBP1 MAPK8 MAPK10

1.26e-074111310471813
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

1.26e-074111319091768
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

3.15e-075111317855024
Pubmed

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.

MYCBP2 MAPK8 MAPK10

1.10e-067111323979718
Pubmed

The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis.

TP63 MAPK8 MAPK10

3.74e-0610111315375216
Pubmed

A human MAP kinase interactome.

SETX MAP4K3 PAK5 POM121C CBLB DDX27 MAP3K4 MAP4K5 KIAA1328 MAPK10

3.79e-064861111020936779
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

1.01e-052111215610184
Pubmed

Expression of p40 and laminin 332 in metaplastic spindle cell carcinoma of the breast compared with other malignant spindle cell tumours.

LAMC2 TP63

1.01e-052111225795733
Pubmed

p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.

RHBDF2 TP63

1.01e-052111229523849
Pubmed

JNK1 inhibits transcriptional and pro-apoptotic activity of TAp63γ.

TP63 MAPK8

1.01e-052111226519559
Pubmed

ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes.

SETX TP63

1.01e-052111235235452
Pubmed

Neuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms.

MAPK8 MAPK10

1.01e-052111228664455
Pubmed

c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.

MAPK8 MAPK10

1.01e-052111221824499
Pubmed

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

CACNA1B CACNA1E

1.01e-052111212074836
Pubmed

Correlation between immunohistochemical expression of Ki-67and P63 and aggressiveness of urinary bladder urothelial carcinoma.

TP63 MKI67

1.01e-052111233206579
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

MAP4K3 CSMD2 TDRD1 PIK3C2B MAP4K5 TPX2 MKI67 TP53BP2

1.12e-05329111817474147
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

1.12e-0514111317662146
Pubmed

Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice.

TP63 MKI67 MAPK8

1.40e-0515111326116174
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

MAP4K3 CBLB PIK3C2B MAP4K5 PEAK1

2.06e-05103111521706016
Pubmed

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

SRY MAP3K4 MAPK8

2.08e-0517111319753101
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PIK3C2B MAPK8 MAPK10

2.08e-0517111312960231
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

TP63 MKI67 MAPK8

2.49e-0518111336057966
Pubmed

Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.

SRY MAP3K4 MKI67

2.49e-0518111323102580
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EPRS1 MIS18BP1 SETX MYCBP2 MAP4K3 FAM98A DDX27 KIF20B SUGP2 GGCT MAP4K5 POP1 MKI67 TP53BP2 PARP12

2.68e-0513531111529467282
Pubmed

HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.

LCT TP63 MKI67

2.95e-0519111331345929
Pubmed

JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy.

MAPK8 MAPK10

3.02e-053111230685843
Pubmed

p63 is an essential proapoptotic protein during neural development.

TP63 MKI67

3.02e-053111216337913
Pubmed

Cataloguing the dead: breathing new life into pseudokinase research.

PSKH1 EPHA10

3.02e-053111232053275
Pubmed

JNK1 is required to preserve cardiac function in the early response to pressure overload.

MAPK8 MAPK10

3.02e-053111216579967
Pubmed

Specific pathophysiological functions of JNK isoforms in the brain.

MAPK8 MAPK10

3.02e-053111215673436
Pubmed

Predictive value of p63, ki-67, and survivin expression in oral leukoplakia: A tissue microarray study.

TP63 MKI67

3.02e-053111228346726
Pubmed

Human c-Jun N-terminal kinase expression and activation in the nervous system.

MAPK8 MAPK10

3.02e-053111210101227
Pubmed

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells.

MAPK8 MAPK10

3.02e-053111223485395
Pubmed

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.

PAK5 MAP3K9

3.02e-053111223836671
Pubmed

Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model.

MAPK8 MAPK10

3.02e-053111217056565
Pubmed

The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases.

MAPK8 MAPK10

3.02e-053111234502556
Pubmed

USP11 controls R-loops by regulating senataxin proteostasis.

SETX KEAP1

3.02e-053111234526504
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1B CACNA1E

3.02e-053111238996073
Pubmed

Differential expression of cyclin E, p63, and Ki-67 in gestational trophoblastic disease and its role in diagnosis and management: A prospective case-control study.

TP63 MKI67

3.02e-053111230706860
Pubmed

Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning.

MAPK8 MAPK10

3.02e-053111220926661
Pubmed

Pin1 and JNK1 cooperatively modulate TAp63γ.

TP63 MAPK8

3.02e-053111233548094
Pubmed

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis.

MAPK8 MAPK10

3.02e-053111219609503
Pubmed

C57BL/6J-T-associated sex reversal in mice is caused by reduced expression of a Mus domesticus Sry allele.

SRY MAP3K4

3.02e-053111211514455
Pubmed

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.

CR1 C1S

3.02e-053111233804666
Pubmed

Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity.

MAPK8 MAPK10

3.02e-053111215246824
Pubmed

A critical role of neural-specific JNK3 for ischemic apoptosis.

MAPK8 MAPK10

3.02e-053111214657393
Pubmed

SAPKgamma/JNK1 and SAPKalpha/JNK2 mRNA transcripts are expressed in early gestation human placenta and mouse eggs, preimplantation embryos, and trophoblast stem cells.

MAPK8 MAPK10

3.02e-053111215474087
Pubmed

ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.

TP63 TP53BP2

3.02e-053111224127607
Pubmed

Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome.

SRY MAP3K4

3.02e-05311122806881
Pubmed

p63 protein is essential for the embryonic development of vibrissae and teeth.

TP63 MKI67

3.02e-053111216410075
Pubmed

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.

MAPK8 MAPK10

3.02e-053111214517246
Pubmed

ASK1/JNK-mediated TAp63 activation controls the cell survival signal of baicalein-treated EBV-transformed B cells.

TP63 MAPK8

3.02e-053111226694167
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1B CACNA1E

3.02e-053111224523520
Pubmed

Knockout of c-Jun N-terminal kinases 1, 2 or 3 isoforms induces behavioural changes.

MAPK8 MAPK10

3.02e-053111223428746
Pubmed

Gene expression profile in JNK3 null mice: a novel specific activation of the PI3K/AKT pathway.

MAPK8 MAPK10

3.02e-053111221255018
Pubmed

P53, p63 and Ki-67 assessment in HPV-induced cervical neoplasia.

TP63 MKI67

3.02e-053111219690760
Pubmed

Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study.

TP63 MKI67

3.02e-053111218256893
Pubmed

Canonical notch signaling functions as a commitment switch in the epidermal lineage.

ITGB6 TP63 MKI67

4.04e-0521111317079689
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MPP3 CRYBG2 RHBDF2 MYCBP2 BCAS3 POM121C NHSL1 SUGP2 PIK3C2B MAPKBP1 SIPA1L2 ULK2 RAI1

5.29e-0511051111335748872
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ZDBF2 KEAP1 NHSL1 PEAK1 SIPA1L2 TP53BP2

5.87e-05209111636779422
Pubmed

An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome.

TP63 MKI67

6.03e-054111223775923
Pubmed

Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).

MAPK8 MAPK10

6.03e-054111215228592
Pubmed

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis.

MAPK8 MAPK10

6.03e-054111212818176
Pubmed

JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.

MAPK8 MAPK10

6.03e-054111220525557
Pubmed

JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases.

MAPK8 MAPK10

6.03e-05411129393873
Pubmed

c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.

MAPK8 MAPK10

6.03e-054111215528206
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1B CACNA1E

6.03e-054111237141091
Pubmed

A selective small-molecule inhibitor of c-Jun N-terminal kinase 1.

MAPK8 MAPK10

6.03e-054111219527717
Pubmed

ASPP1 and ASPP2: common activators of p53 family members.

TP63 TP53BP2

6.03e-054111214729977
Pubmed

Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

MAP3K4 MAPK8

6.03e-054111215731347
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1B CACNA1E

6.03e-054111232616470
Pubmed

c-JUN N-terminal kinase-1 (JNK1) but not JNK2 or JNK3 is involved in UV signal transduction in human epidermis.

MAPK8 MAPK10

6.03e-054111216824735
Pubmed

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

MAPK8 MAPK10

6.03e-054111222372722
Pubmed

Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein.

MAPK8 MAPK10

6.03e-054111215693750
Pubmed

MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival.

MAPK8 MAPK10

6.03e-054111217724133
Pubmed

APP upregulation contributes to retinal ganglion cell degeneration via JNK3.

MAPK8 MAPK10

6.03e-054111229238071
Pubmed

Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation.

MAP3K4 MAPK8

6.03e-054111212878610
Pubmed

Cortical interneurons require Jnk1 to enter and navigate the developing cerebral cortex.

MAPK8 MAPK10

6.03e-054111224899703
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MAP4K3 ANKRD50 CBLB NHSL1 PIK3C2B MAP4K5 PEAK1 SIPA1L2

6.43e-05421111836976175
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

MAP4K3 CBLB NHSL1 PEAK1 SIPA1L2 TP53BP2

7.41e-05218111633378226
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MYCBP2 ZFC3H1 POM121C DDX27 MAP3K4 POP1 TPX2 MKI67

8.73e-05440111834244565
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1B CACNA1E

1.00e-04511128825650
Pubmed

Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase.

GGT3P GGTLC3

1.00e-04511122904146
Pubmed

The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.

MAPK8 MAPK10

1.00e-045111212714584
Pubmed

Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons.

MAPK8 MAPK10

1.00e-04511129403476
Pubmed

The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity.

MAPK8 MAPK10

1.00e-045111216007099
Pubmed

SPECC1L regulates palate development downstream of IRF6.

TP63 MKI67

1.00e-045111231943082
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1B CACNA1E

1.00e-045111211296258
Pubmed

Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73.

TP63 TP53BP2

1.00e-045111218275817
Pubmed

gp160 of HIV or anti-CD4 monoclonal antibody ligation of CD4 induces inhibition of JNK and ERK-2 activities in human peripheral CD4+ T lymphocytes.

MAPK8 MAPK10

1.00e-04511129045910
Pubmed

Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses.

CACNA1E LAMC2

1.00e-04511129927670
Pubmed

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease.

MAPK8 MAPK10

1.00e-045111214704277
Pubmed

Expression of multiple gamma-glutamyltransferase genes in man.

GGT3P GGTLC3

1.00e-04511127906515
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1B CACNA1E

1.00e-045111215451373
Pubmed

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

MAPK8 MAPK10

1.00e-045111210230788
Pubmed

Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.

MAPK8 MAPK10

1.00e-045111220534829
Pubmed

JNK regulates the photic response of the mammalian circadian clock.

MAPK8 MAPK10

1.00e-045111222441692
Pubmed

cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein.

MAPK8 MAPK10

1.00e-045111210756100
Pubmed

A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.

KEAP1 ASTN1

1.00e-045111231169361
Cytoband22q11.21

GGT3P RIMBP3 GGTLC3 RIMBP3C RIMBP3B

7.89e-06111111522q11.21
Cytoband1p34.3

CSMD2 ZSCAN20 EPHA10

4.69e-046211131p34.3
GeneFamilyMitogen-activated protein kinase kinase kinase kinases

MAP4K3 MAP4K5

1.60e-045732655
GeneFamilyMitogen-activated protein kinases

MAPK8 MAPK10

1.22e-0313732651
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT3P GGTLC3

1.22e-0313732564
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 CR1 C1S

1.58e-03577331179
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

GPKOW SUGP2

3.53e-0322732579
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K4 MAP3K9

4.19e-0324732654
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA1E

4.91e-0326732253
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

MPP3 CACNA1E FKBP15 THSD7A MYCBP2 SOBP PAK5 POU2F2 LAMC2 PITPNC1 CSMD2 CHRM5 FSIP2 SUGP2 MAP3K9 MDGA1 NDRG4 RAI1

6.91e-07110610918M39071
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B PLB1 PAK5 DGKB SAXO1 C1S ASTN1

1.57e-071601117c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B PLB1 PAK5 DGKB SAXO1 C1S ASTN1

1.57e-07160111725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellFibroblast-E_(Early_Fibroblastic_progenitor)|World / shred on cell class and cell subclass (v4)

MIS18BP1 KIF20B FBN1 CCNE2 TPX2 MKI67 JAM3

4.68e-071881117be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA1B CACNA1E MYCBP2 ZDBF2 CHRM5 ANKRD34B EPHA10

4.68e-071881117b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 KIF20B CCNE2 TPX2 MKI67 C1S

3.66e-06165111696f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MIS18BP1 KIF20B CCNE2 TP63 TPX2 MKI67

3.92e-061671116bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B IGSF10 FBN1 TPX2 MKI67

5.13e-061751116a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B PAK5 POU2F2 PTPRR MAPK10 NDRG4

6.03e-061801116368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PAK5 DGKB RIMBP3 PTPRR NDRG4 EPHA10

6.42e-061821116a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA1B MYCBP2 ZDBF2 ANKRD34B NDRG4 EPHA10

7.27e-0618611169d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MPP3 CACNA1B MYCBP2 ZDBF2 NDRG4 EPHA10

8.21e-061901116416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

SOBP LAMC2 CBLB FBN1 C1S MUSK

8.21e-06190111612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MPP3 CACNA1B CACNA1E MYCBP2 ZDBF2 NDRG4

8.72e-0619211164c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SOBP PITPNC1 CBLB FBN1 C1S MUSK

9.25e-06194111611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C THSD7A ITPKB PIK3C2B SIPA1L2 JAM3

9.25e-0619411160b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellproximal-3-Endothelial-Vein|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PSKH1 PITPNC1 PIK3C2B PTPRR MDGA1 NDRG4

9.52e-061951116c81eb541c15b866f9b6ca6a5f1751c5f1243f4fb
ToppCellproximal-Endothelial-Vein-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PSKH1 PITPNC1 PIK3C2B PTPRR MDGA1 NDRG4

9.52e-061951116df00f94facc5d6107aac83cef3c64fefc7f8e562
ToppCellproximal-Endothelial-Vein|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PSKH1 PITPNC1 PIK3C2B PTPRR MDGA1 NDRG4

9.52e-0619511160aebdd635a956dd2367883c1cf73d73ce9790635
ToppCellsevere-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PITPNC1 LCT CBLB GPKOW ECI2 CNN2

9.80e-06196111614baf176bce5750ef50d6838b748caf68c151e05
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B POU2F2 PTPRR ASTN1 MAPK10 NDRG4

1.01e-05197111627c044833e471a312a572e0b1c83e4bc8a36e896
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MIS18BP1 CR1 KIF20B TPX2 MKI67 SIPA1L2

1.01e-051971116d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellsevere-dn_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PITPNC1 LCT CBLB GPKOW ECI2 CNN2

1.04e-051981116d4f2213af45ada47e6c62675f468ce05692db507
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

MAP4K3 BCAS3 NHSL1 KIAA1328 PEAK1 MAPK10

1.04e-0519811161996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1B CACNA1E MYCBP2 PAK5 ANKRD50 PTPRR

1.10e-052001116bad32a95b759fad509401b07bc96a56687c2a592
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PSKH1 POM121C ZNF836 KIAA1328 C1S

2.67e-0514011150e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITPNC1 CBLB GPKOW ECI2 CNN2

3.96e-051521115405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITPNC1 CBLB GPKOW ECI2 CNN2

3.96e-05152111506fa7d8acc8f56de00af9bee17884595b300410e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITPNC1 CBLB GPKOW ECI2 CNN2

4.08e-051531115b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PITPNC1 CBLB GPKOW ECI2 CNN2

4.08e-051531115487388082bb596809ba1caf9197626b6814792ab
ToppCellCOVID-19_Severe-Lymphoid_T/NK-dn_T|COVID-19_Severe / Disease group, lineage and cell class

PITPNC1 CBLB GPKOW ECI2 CNN2

4.48e-05156111583f25683e0f55472b56f915ee176fc05efc33a31
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CACNA1B PAK5 KEAP1 ITPKB SIPA1L2

5.68e-05164111581c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA1 MIS18BP1 TPX2 MKI67 ULK2

6.02e-051661115bb8135119dc37fdbba476599a56d368f422688dc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB ZNF18 C1S MAPK10 MDGA1

6.02e-0516611159e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GGCT TPX2 MKI67 MAPKBP1 MDGA1

6.02e-05166111543f84d3cd58e93ce00c241656c4cba27604b4932
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

6.19e-05167111550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYBG2 ITGB6 GGCT TP63 MUSK

6.19e-05167111569caf4a53805f8c104d7dd8f88665fc992e23720
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP15 MIS18BP1 TPX2 MKI67 SIPA1L2

6.37e-0516811159b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP15 MIS18BP1 TPX2 MKI67 SIPA1L2

6.37e-0516811154b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP15 MIS18BP1 TPX2 MKI67 SIPA1L2

6.37e-051681115c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEXMIF PSKH1 KIF20B DPP9 CCNE2

6.37e-05168111508f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 FBN1 C1S MAPK10 MUSK

6.55e-051691115c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

6.55e-051691115bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B PIK3C2B TPX2 MKI67

6.73e-051701115e08a6c5ac34c456da8c7318f104e06fca585be1f
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B FBN1 TPX2 MKI67

7.12e-051721115c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LILRB2 POU2F2 CR1 TPX2 MKI67

7.12e-051721115ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NEXMIF PITPNC1 CCNE2 TPX2 MKI67

7.31e-05173111520889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NEXMIF PITPNC1 CCNE2 TPX2 MKI67

7.31e-05173111546e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 MIS18BP1 KIF20B TPX2 MKI67

7.52e-05174111572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 MIS18BP1 KIF20B TPX2 MKI67

7.52e-051741115c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MIS18BP1 KIF20B IHO1 TPX2 MKI67

7.52e-051741115dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CSMD2 IGSF10 TPX2 MKI67 ULK2

7.72e-051751115cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CSMD2 IGSF10 TPX2 MKI67 ULK2

7.72e-051751115a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOBP ANKRD50 FBN1 PTPRR PEAK1

7.72e-0517511151b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B PTPRR TPX2 MKI67

7.72e-051751115d43ae33a6256606ce848247cad32d74f21b38988
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B TPX2 MKI67 C1S

7.72e-05175111515c69dd5635c9251c535f1e22467712e9667ae92
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CSMD2 IGSF10 TPX2 MKI67 ULK2

7.72e-0517511158a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 DGKB KIF20B TPX2 MKI67

7.72e-0517511153e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CSMD2 IGSF10 TPX2 MKI67 ULK2

7.72e-051751115378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MPP3 MIS18BP1 KIF20B TPX2 MKI67

7.93e-0517611158385435074cc5235b7af7424974f609388fc2cff
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

8.59e-05179111554191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 LAMC2 KIF20B TPX2 MKI67

8.59e-051791115dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

8.82e-0518011155e1680088065be14447d5d5465f91f7edd071a1e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CSMD2 KIF20B CCNE2 TPX2 MKI67

8.82e-051801115f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-0518111150c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-051811115e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-051811115f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-0518111152be3d44619adb25d339e7a27b500a56e07e8de01
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-051811115cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20B TPX2 MKI67 MAP3K9 MAPKBP1

9.05e-0518111153fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-05181111574311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCellLymphoid-Lymphoid-T_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

9.05e-051811115b6b41cd5d43543fe7a093033dae52a789199db0e
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 LAMC2 ITGB6 ANKRD34B TP53BP2

9.29e-051821115573771130247e869e4e58f22d4a1cb31989635cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC2 IQCN ITGB6 ULK2 RAI1

9.29e-051821115a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 LAMC2 ITGB6 ANKRD34B TP53BP2

9.29e-0518211156cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLB1 DGKB LAMC2 ITGB6 TPX2

9.78e-05184111561caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLB1 DGKB LAMC2 ITGB6 TPX2

9.78e-05184111503da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLB1 DGKB LAMC2 ITGB6 TPX2

9.78e-0518411159ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.00e-0418511150e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.00e-04185111589b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCellInfluenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class

ABCA1 PEX12 CR1 MANSC1 ANKRD34B

1.03e-0418611151dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF20B IHO1 FBN1 TPX2 MKI67

1.05e-041871115e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF20B IHO1 FBN1 TPX2 MKI67

1.05e-041871115cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPT NHSL1 TP63 MAPKBP1 CNN2

1.05e-0418711159c1013720c248ef201d010806b6e7ad24205e8ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MIS18BP1 POU2F2 KIF20B TPX2 MKI67

1.05e-04187111573931a5ea73799095daff100b5f18853c57c74dc
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.08e-041881115b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPT NHSL1 TP63 MAPKBP1 CNN2

1.08e-0418811158cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 KIF20B TPX2 MKI67 MAPK10

1.11e-041891115815afad947ed77a8b03724bf78014799fed34f54
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOBP IGSF10 FBN1 C1S ASTN1

1.11e-041891115f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOBP IGSF10 FBN1 C1S ASTN1

1.11e-041891115378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A FBN1 PIK3C2B NDRG4 JAM3

1.11e-041891115b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB FBN1 PEAK1 MUSK JAM3

1.14e-0419011151121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB FBN1 PEAK1 MUSK JAM3

1.14e-041901115048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.16e-04191111515dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCellEndothelial-D_(cycle)|World / shred on cell class and cell subclass (v4)

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.16e-04191111549a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.16e-04191111545c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.16e-041911115a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

SOBP CBLB FBN1 C1S MUSK

1.16e-041911115d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C THSD7A FBN1 PIK3C2B NDRG4

1.16e-0419111154b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

SOBP FBN1 C1S MAPK10 MUSK

1.19e-041921115356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 KIF20B CCNE2 TPX2 MKI67

1.19e-041921115e8d47504b744040a762ec9b670a66cc060b2ae86
Drugalmagel

CACNA1B CACNA1E LCT

1.03e-0651083CID003080942
Drugirisolidone

GPT MAPK8 MAPK10

1.22e-05101083CID005281781
DrugAC1NURR2

GPT MAPK8 MAPK10

1.67e-05111083CID005490351
Drugaristolactam AII

CACNA1B CACNA1E

2.23e-0521082CID000148657
Drugalkosin

CACNA1B CACNA1E

2.23e-0521082CID005488638
Drugnorcepharadione B

CACNA1B CACNA1E

2.23e-0521082CID000189168
Drugpiperolactam A

CACNA1B CACNA1E

2.23e-0521082CID003081016
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1B CACNA1E

3.68e-0531042DOID:0111181 (implicated_via_orthology)
DiseaseMetastatic melanoma

PAK5 MAP3K9 PEAK1 ULK2

4.02e-05541044C0278883
Diseasemigraine (implicated_via_orthology)

CACNA1B CACNA1E

7.35e-0541042DOID:6364 (implicated_via_orthology)
DiseaseMANSC domain-containing protein 1 measurement

MANSC1 MAP4K5

7.35e-0541042EFO_0801784
Diseaseeosinophil count

PLB1 RHBDF2 POU2F2 CBLB ITGB6 ITPKB IHO1 PIK3C2B MAP4K5 C1S PEAK1 MUSK CNN2 EPHA10 RAI1

2.25e-04148810415EFO_0004842
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1B CACNA1E

2.55e-0471042DOID:0050951 (implicated_via_orthology)
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT3P GGTLC3

2.55e-0471042DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT3P GGTLC3

3.40e-0481042DOID:0050741 (biomarker_via_orthology)
Disease1-stearoyl-2-docosapentaenoyl-GPC (18:0/22:5n3) measurement

MAP4K5 MUSK

3.40e-0481042EFO_0800455
Diseasetriglyceride measurement, alcohol drinking

MPP3 PLB1 ABCA1 MUSK

4.24e-04991044EFO_0004329, EFO_0004530
Diseasetriglyceride measurement, alcohol consumption measurement

MPP3 PLB1 ABCA1 MUSK

4.57e-041011044EFO_0004530, EFO_0007878
Disease1-palmitoyl-2-oleoyl-GPE (16:0/18:1) measurement

MAP4K5 MUSK

5.44e-04101042EFO_0800608
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement

MAP4K5 MUSK

5.44e-04101042EFO_0800507
Diseasesystolic blood pressure, self reported educational attainment

THSD7A ANKRD34B

5.44e-04101042EFO_0004784, EFO_0006335
Disease1-stearoyl-2-oleoyl-GPE (18:0/18:1) measurement

MAP4K5 MUSK

6.63e-04111042EFO_0800269
Diseasemeningitis

CACNA1E ITPKB

6.63e-04111042MONDO_0021108
Diseasephosphatidylcholine 34:4 measurement

MAP4K5 MUSK

7.94e-04121042EFO_0010378
Diseasetriacylglycerol 53:2 measurement

MAP4K5 MUSK

7.94e-04121042EFO_0021484
Disease1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement

MAP4K5 MUSK

7.94e-04121042EFO_0800453
Diseaseextrapulmonary tuberculosis

THSD7A DGKB

7.94e-04121042MONDO_0000368
Diseaselevel of Phosphatidylcholine (16:0_20:2) in blood serum

MAP4K5 MUSK

7.94e-04121042OBA_2045074
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

MPP3 ABCA1 MAP4K5 MAPKBP1 MUSK RAI1

8.92e-043151046EFO_0004612, EFO_0008591
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

MPP3 ABCA1 MAP4K5 MAPKBP1 MUSK RAI1

8.92e-043151046EFO_0004574, EFO_0004612
Diseasesleep duration, high density lipoprotein cholesterol measurement

ABCA1 LILRB2 PSKH1 MUSK

9.02e-041211044EFO_0004612, EFO_0005271
DiseasePeripheral Nervous System Diseases

CACNA1B ABCA1 MKI67

9.26e-04541043C4721453
Diseaselevel of Phosphatidylcholine (16:0_18:3) in blood serum

MAP4K5 MUSK

9.36e-04131042OBA_2045072
Diseaselevel of Phosphatidylcholine (16:1_18:1) in blood serum

MAP4K5 MUSK

9.36e-04131042OBA_2045082
Diseasetriglycerides in large VLDL measurement

MPP3 MAP4K5 MUSK

1.03e-03561043EFO_0022178
Diseaseresponse to methotrexate, aspartate aminotransferase measurement

PLB1 PITPNC1

1.09e-03141042EFO_0004736, GO_0031427
Diseaselevel of Phosphatidylethanolamine (18:2_0:0) in blood serum

MAP4K5 MUSK

1.09e-03141042OBA_2045143
Diseaselipid measurement, high density lipoprotein cholesterol measurement

MPP3 ABCA1 MAP4K5 MAPKBP1 MUSK RAI1

1.13e-033301046EFO_0004529, EFO_0004612
Diseaselevel of Triacylglycerol (53:3) in blood serum

MAP4K5 MUSK

1.25e-03151042OBA_2045165
Diseasetriglycerides in medium LDL measurement

ABCA1 MAP4K5 MUSK

1.38e-03621043EFO_0022322
Diseasevitamin C measurement

BCAS3 MUSK

1.43e-03161042EFO_0600003
Diseasephosphatidylcholine 32:2 measurement

MAP4K5 MUSK

1.43e-03161042EFO_0010374
Diseaseurate measurement, bone density

PLB1 ITGB6 ITPKB FSIP2 MANSC1 MAP4K5 PEAK1 MAPK8

1.58e-036191048EFO_0003923, EFO_0004531
Diseasecholesterol in very large VLDL measurement

MPP3 MAP4K5 MUSK

1.59e-03651043EFO_0022230
Diseaselevel of Phosphatidylcholine (14:0_18:2) in blood serum

MAP4K5 MUSK

1.62e-03171042OBA_2045063
Diseasetotal lipids in very large HDL measurement

ABCA1 MAP4K5 MUSK

1.66e-03661043EFO_0022312
DiseaseAlzheimer disease

ABCA1 BCAS3 LILRB2 CR1 C1S SIPA1L2 CNN2

1.68e-034851047MONDO_0004975
Diseasetotal lipids in large VLDL

MPP3 MAP4K5 MUSK

1.73e-03671043EFO_0022175
Diseasefatty acid measurement, linoleic acid measurement

MAP4K5 C1S MUSK

1.81e-03681043EFO_0005110, EFO_0006807
Diseaselysophosphatidylcholine 22:6 measurement

SIPA1L2 MUSK

1.81e-03181042EFO_0010365
Diseasecholesterol in very large HDL measurement

ABCA1 MAP4K5 MUSK

1.88e-03691043EFO_0022229
DiseaseHypertriglyceridemia

LAMC2 MAP4K5

2.02e-03191042EFO_0004211
Diseaseleucine measurement

DCDC1 MAP4K5 MAPK10

2.21e-03731043EFO_0009770
Diseaserenal system measurement

DCDC1 BCAS3

2.24e-03201042EFO_0004742
Diseasecoagulation factor V measurement

PAK5 MUSK

2.24e-03201042EFO_0008087
Diseasenon-small cell lung carcinoma

SAXO1 TP63 MUSK

2.39e-03751043EFO_0003060
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

ABCA1 MUSK

2.47e-03211042OBA_2045104
Diseaselevel of Phosphatidylcholine (16:1_18:2) in blood serum

MAP4K5 MUSK

2.47e-03211042OBA_2045083
Diseaserenal system measurement, blood urea nitrogen measurement

DCDC1 BCAS3

2.71e-03221042EFO_0004741, EFO_0004742
Diseasetriacylglycerol 54:6 measurement

MAP4K5 MUSK

2.71e-03221042EFO_0010424
Diseasefree cholesterol in large HDL measurement

ABCA1 MAP4K5 MUSK

2.77e-03791043EFO_0022157
Diseasemosaic loss of chromosome Y measurement

FAM117A TPX2 SLC35B1

2.87e-03801043EFO_0007783
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

MPP3 ABCA1 MAP4K5 MUSK

2.87e-031661044EFO_0004530, EFO_0004611
DiseaseBMI-adjusted fasting blood glucose measurement

MAP4K5 MUSK

2.97e-03231042EFO_0008036
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

MAP4K5 MUSK

2.97e-03231042OBA_2045158
Diseasehigh density lipoprotein particle size measurement

ABCA1 MAP4K5 MUSK RAI1

3.13e-031701044EFO_0008592
Diseaseairway responsiveness measurement

BCAS3 SOBP

3.23e-03241042EFO_0006897
Diseaselevel of Phosphatidylethanolamine (16:0_18:2) in blood serum

MAP4K5 MUSK

3.23e-03241042OBA_2045136
Diseasestomach carcinoma (is_marker_for)

CBLB KDM4A

3.23e-03241042DOID:5517 (is_marker_for)
Diseasealpha-linolenic acid measurement

LCT MUSK

3.50e-03251042EFO_0007759
Diseasesystemic mastocytosis

CACNA1E ABCA1

3.50e-03251042MONDO_0016586
Diseasediacylglycerol 34:2 measurement

MAP4K5 MUSK

3.50e-03251042EFO_0010353
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

DGKB MAP4K5

3.50e-03251042EFO_0004465, EFO_0004466, EFO_0004469
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

MPP3 MAP4K5 MUSK

3.52e-03861043EFO_0008595, EFO_0020945

Protein segments in the cluster

PeptideGeneStartEntry
PMQAIKCVLAGVKPS

TDRD1

601

Q9BXT4
LKLMSVRLCPPVPGQ

GPT

341

P24298
GIPCNIKITDMPPLL

DCAF17

271

Q5H9S7
NGTKPVCKALMCKPP

CSMD2

3001

Q7Z408
MSPPLGLGKRCPSKV

CACNA1E

1771

Q15878
PTGSAFCPVNLMKPL

FAM117A

376

Q9C073
SSDKIKKMLPVCPPG

ABCA1

1466

O95477
QLSPVCNGGIMTPPK

CCNE2

381

O96020
CNGGIMTPPKSTEKP

CCNE2

386

O96020
AAPPKQMPAESQCKI

ANKRD50

1316

Q9ULJ7
KMKGCPVNTEPSGPT

HCCS

31

P53701
CKVKPPPQISPSKSM

BCAS3

561

Q9H6U6
KMQKPSCGIVPLASP

C2orf73

121

Q8N5S3
MSPPLGLGKKCPARV

CACNA1B

1756

Q00975
MGFKQPTPIQKACIP

DDX27

236

Q96GQ7
VVPSMGTKPKPAGQQ

TP53BP2

536

Q13625
GAKSPCAMPSQVPDK

ASTN1

1096

O14525
GMQDPLSPKAPLICT

RAI1

886

Q7Z5J4
ALCPAPSAKVIKMPR

RIMBP3B

1426

A6NNM3
ALCPAPSAKVIKMPR

RIMBP3C

1426

A6NJZ7
PFQICPGPMITKTLL

IQCN

326

Q9H0B3
SLLSCGQKVLMPTVP

ANKRD34B

471

A5PLL1
CPRKQTDPNKVVVMP

MDGA1

916

Q8NFP4
PSCITPIQLAPMKTI

PAK5

56

Q9P286
KLAGPPSCIVPLMRQ

PAK5

701

Q9P286
FIQPGKQPLLSMCPT

GGT3P

441

A6NGU5
VPSSPPMKKPICKTT

DCDC1

916

M0R2J8
LPPTPKVHMGACFSK

MAP4K3

536

Q8IVH8
PLVKTPQCQHVSPGM

MIS18BP1

1031

Q6P0N0
TPCPEFMKKLQPTVR

MAPK10

281

P53779
PVCPILGGTVMPNKT

IHO1

511

Q8IYA8
MGCGTSKVLPEPPKD

PSKH1

1

P11801
ALPAMKGKNTIICAP

DDX58

251

O95786
PTGSPKSSPCMVRKQ

CBLB

526

Q13191
PPPITCSSLGKKYLM

FSIP2

4156

Q5CZC0
ATMPQVPGGSVKPKI

NHSL1

826

Q5SYE7
SINEKDCPKPPNIPM

ITGB6

696

P18564
LGTPCPEFMKKLQPT

MAPK8

241

P45983
KLPPSCMIGGIKETQ

PEAK1

191

Q9H792
PMAAKPDNPSGKVCV

FKBP15

1066

Q5T1M5
QPNKMAVKHPGCTTP

KIF20B

1631

Q96Q89
KEKRINPCSAAPMLP

POU2F2

351

P09086
APQKQRTKPLIPEMC

KDM4A

696

O75164
LKLPDCPSTMKNPAS

LCT

281

P09848
VSKKPSLSVQPGPVM

LILRB2

221

Q8N423
PNEEACPLKPAKGLM

MANSC1

101

Q9H8J5
PTLAIPMIQKGCTPS

GPKOW

126

Q92917
ESAPPSPQYKKIICM

GGCT

131

O75223
TPVCRVPKAVPVGKM

JAM3

141

Q9BX67
KITKMPCQSLQPEPI

MKI67

1001

P46013
MTIDKNTKIPCKSPP

MKI67

2576

P46013
SKMVQDPEPPKCALT

EPHA10

901

Q5JZY3
SLRPPKKLMPCASCT

H1-10-AS1

41

Q4G0G2
CESPGRKPAVPTEKM

KIAA1328

271

Q86T90
PGKQPLLSMCPTIMV

GGTLC3

101

B5MD39
VCPSPFKMKPIGLQE

PTPRR

321

Q15256
CPSRMQPKIQKDPSV

PIK3C2B

561

O00750
MQTCNTKFPGPKSIP

PARP12

471

Q9H0J9
ESLKKMQTPPSLPPC

POM121C

576

A8CG34
SEVPCAPMPKKTHQP

POP1

741

Q99575
KGSPEPHTMICVPAK

POP1

866

Q99575
AKTCPIQIKVMTPPP

TP63

206

Q9H3D4
ALVPLKTPMPCLGAK

CCDC71

181

Q8IV32
PLCMNPRTSKGKPLA

IGSF10

256

Q6WRI0
PACVGKRMQPSPTGK

C9orf92

31

A6NGG3
RKSCKTPPDPVNGMV

CR1

551

P17927
RKSCKTPPDPVNGMV

CR1

1001

P17927
MIIPCLGFPQSLKSK

DNAH17

61

Q9UFH2
KTQCSGPRMDPKICP

DPP9

181

Q86TI2
NKLCSVPMVIPGRPE

FBN1

386

P35555
PALIQLISKTPCMPQ

GPR148

16

Q8TDV2
SLKPMRLGCPSVEKP

CRYBG2

1151

Q8N1P7
KVPGMKPDCKSSPIT

IGFL4

91

Q6B9Z1
KDPVKMGPTVSPICL

C1S

536

P09871
LMGPPPKTGLFCSLV

DGKB

781

Q9Y6T7
CGMKPPFLPEALLTV

CYP4F30P

91

Q9H0H9
EKTPNPMECTKPGAA

MAPKBP1

1391

O60336
HKPTQVMPCRAPKVG

KEAP1

311

Q14145
ITAPLMPLGKTLPCG

LAMC2

296

Q13753
PCNMPKPGVFDLINK

ECI2

76

O75521
VAMNKLALPIPSTCP

MAP3K9

361

P80192
SPCSVLSPMSKPKFI

FAM166A

51

Q6J272
LPPTPKVLMGACFSK

MAP4K5

486

Q9Y4K4
AIQEKRKTPPMSPAC

MPP3

506

Q13368
LGCSNAKLPVSVPMP

MAP3K4

191

Q9Y6R4
APSMGAKSLCIPFKP

EPRS1

1471

P07814
QKMKSCLLDLPPTPV

SMYD4

786

Q8IYR2
ISCKPLAMPKLCNIP

SAXO1

186

Q8IYX7
SKPMDLKLCTGPIPN

THSD7A

486

Q9UPZ6
ALCPAPSAKVIKMPR

RIMBP3

1426

Q9UFD9
GSCKSQRPMFPPIHK

SPATA31A6

1091

Q5VVP1
LKGICIALGMSKPPA

FAM98A

146

Q8NCA5
CSSQVKKGMPPLPGR

ITPKB

226

P27987
KPCMQSPPSPLGLIE

NEXMIF

71

Q5QGS0
KSKCADPGLMPLPDT

SIPA1L2

1556

Q9P2F8
GDPKQLPPTVISMKA

SETX

2206

Q7Z333
NMIFPSPGSCAVLKK

MYCBP2

3181

O75592
PGTVPNAKTLRCPVM

NDRG4

216

Q9ULP0
EPLSVKHGRPMKCPS

PLB1

321

Q6P1J6
NSDSPLLPKMKTVCP

PEX12

291

O00623
PTQVLGKSCKPIPVM

SLC35B1

111

P78383
GKSCKPIPVMLLGVT

SLC35B1

116

P78383
KIMPCPFPVAKEPST

CHRM5

401

P08912
PAQSIKCAMINIKPG

CNBD2

386

Q96M20
CTLMNKLQPGSVPKI

CNN2

61

Q99439
AVKPSTLCPKAPDMG

ZSCAN20

611

P17040
CVIQPVPKPAEKAAM

SOBP

826

A7XYQ1
VPKPAEKAAMAPCII

SOBP

831

A7XYQ1
GMIPAPKRVCLIQEP

SUGP2

961

Q8IX01
NLPGMHSSDKPCRPK

PITPNC1

316

Q9UKF7
EFPASCTKVLKPMQP

ZDBF2

1991

Q9HCK1
VKKSCPVPVPMYSGS

ULK2

276

Q8IYT8
CLKGMLIPCIPKIQS

ZUP1

381

Q96AP4
KMLPKNCSLLPADPA

SRY

136

Q05066
FLKSATVVQPPGMPC

ZBTB49

116

Q6ZSB9
KGQPRAPMAQKLPTC

ZNF18

396

P17022
SFQGTESPKPCKMPK

RHBDF2

171

Q6PJF5
AQSKTMEVKPCPFRP

ZFC3H1

1131

O60293
FLGILPKCMTKELPP

ZNF836

46

Q6ZNA1
PKCMTKELPPIGNSN

ZNF836

51

Q6ZNA1
SPEKAKGRHTVPCMP

TPX2

186

Q9ULW0
KGRHTVPCMPPAKQK

TPX2

191

Q9ULW0
VPCMPPAKQKFLKST

TPX2

196

Q9ULW0
PSPANPITVEMKGLK

LRRC8C

86

Q8TDW0
LKAVLPCTTMGNPKP

MUSK

136

O15146