Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1	4.44e-06	5	159	3	GO:0090131
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	CUL3 KBTBD6 KBTBD8 KBTBD7 KLHL13	1.15e-05	39	160	5	GO:0031463
Domain	Gal_Oxase/kelch_b-propeller	ATRN KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	9.29e-06	59	155	6	IPR011043
Domain	Kelch_1	ATRN KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	2.51e-05	70	155	6	PF01344
Domain	Kelch_1	ATRN KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	2.51e-05	70	155	6	IPR006652
Domain	ACTINS_1	ACTA1 ACTA2 ACTC1	3.05e-05	8	155	3	PS00406
Domain	BTB	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5	1.12e-04	131	155	7	PF00651
Domain	Kelch	KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	1.19e-04	58	155	5	SM00612
Domain	BTB	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5 KCNS3	1.31e-04	180	155	8	SM00225
Domain	BACK	KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	1.40e-04	60	155	5	SM00875
Domain	BACK	KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	1.51e-04	61	155	5	IPR011705
Domain	BACK	KLHL10 KBTBD6 KBTBD8 KBTBD7 KLHL13	1.51e-04	61	155	5	PF07707
Domain	BTB/POZ_dom	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5 KCNS3	1.59e-04	185	155	8	IPR000210
Domain	SKP1/BTB/POZ	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5 KCNS3	1.84e-04	189	155	8	IPR011333
Domain	Actin_CS	ACTA1 ACTA2 ACTC1	2.90e-04	16	155	3	IPR004001
Domain	ACTINS_2	ACTA1 ACTA2 ACTC1	3.50e-04	17	155	3	PS00432
Domain	BTB	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5	3.82e-04	160	155	7	PS50097
Domain	COE	EBF3 EBF1	4.06e-04	4	155	2	PS01345
Domain	Bestrophin	BEST3 BEST4	4.06e-04	4	155	2	PF01062
Domain	Transcription_factor_COE	EBF3 EBF1	4.06e-04	4	155	2	IPR003523
Domain	Bestrophin/UPF0187	BEST3 BEST4	4.06e-04	4	155	2	IPR021134
Domain	COE_HLH	EBF3 EBF1	4.06e-04	4	155	2	IPR032201
Domain	COE_DBD	EBF3 EBF1	4.06e-04	4	155	2	IPR032200
Domain	Bestrophin	BEST3 BEST4	4.06e-04	4	155	2	IPR000615
Domain	Transcription_factor_COE_CS	EBF3 EBF1	4.06e-04	4	155	2	IPR018350
Domain	COE1_HLH	EBF3 EBF1	4.06e-04	4	155	2	PF16423
Domain	COE1_DBD	EBF3 EBF1	4.06e-04	4	155	2	PF16422
Domain	Actin/actin-like_CS	ACTA1 ACTA2 ACTC1	4.17e-04	18	155	3	IPR020902
Domain	BTB-kelch_protein	KLHL10 KBTBD8 KBTBD7 KLHL13	4.38e-04	43	155	4	IPR017096
Domain	ACTINS_ACT_LIKE	ACTA1 ACTA2 ACTC1	4.93e-04	19	155	3	PS01132
Domain	-	ATRN KBTBD6 KBTBD8 KBTBD7	6.68e-04	48	155	4	2.120.10.80
Domain	Kelch-typ_b-propeller	ATRN KBTBD6 KBTBD8 KBTBD7	1.12e-03	55	155	4	IPR015915
Domain	PKD	PKD1L1 SORCS3	1.40e-03	7	155	2	PF00801
Pubmed	Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.	CUL3 CAND1 KBTBD6 GPS1 KBTBD8 KBTBD7 KLHL13	9.08e-09	57	162	7	34878901
Pubmed	Dimerization quality control ensures neuronal development and survival.	CUL3 KBTBD6 KBTBD8 KBTBD7 KLHL13	8.15e-08	24	162	5	30190310
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	9.92e-08	3	162	3	7780165
Pubmed	TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 Signaling.	DVL2 GLI2 TBX1	9.92e-08	3	162	3	31963474
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1 TBX1	1.46e-07	11	162	4	22207710
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	CUL3 CAND1 KBTBD6 GPS1 KBTBD8 KBTBD7 KLHL13	1.79e-07	87	162	7	37495603
Pubmed	Regulating the functions of the HIV-1 matrix protein.	ACTA1 ACTA2 ACTC1 KPNA1	4.38e-07	14	162	4	17411366
Pubmed	Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin.	ACTA1 ACTA2 CCT5	9.85e-07	5	162	3	11580270
Pubmed	Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways.	ACTA2 DLX2 TBX1	9.85e-07	5	162	3	11971873
Pubmed	The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development.	ACTA1 ACTC1 ADAR	9.85e-07	5	162	3	32362246
Pubmed	The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells.	CUL3 DVL2 GLI2	9.85e-07	5	162	3	27477274
Pubmed	Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.	ACTA1 ACTA2 ACTC1 TEAD1	1.66e-06	19	162	4	18316483
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	9971772
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	10074138
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	11709093
Pubmed	Tbx1 regulates proliferation and differentiation of multipotent heart progenitors.	ACTA2 ACTC1 TBX1	1.96e-06	6	162	3	19745164
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	12009869
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	23017337
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTC1	1.96e-06	6	162	3	9841925
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	22535526
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	22640593
Pubmed	Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.	CUL3 KBTBD6 KBTBD7	3.42e-06	7	162	3	33990333
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	17504171
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	22465675
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	3.42e-06	7	162	3	30289203
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 CAND1 UGGT1 GPS1 ACTA2 CKAP5 HNRNPA2B1 KBTBD7 PDIA4 CCT5 KLHL13 KPNA1	3.96e-06	495	162	12	28581483
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CUL3 CAND1 MAN2B1 EIF4A3 UGGT1 GPS1 ACTA1 DVL2 HNRNPA2B1 AKAP12 PDIA4 BLMH RBM12 KIF15 CCT5 PLPBP RIC8A SMS DNM1 DYNC1H1 KPNA1	4.44e-06	1455	162	21	22863883
Pubmed	Fibulin-1 is required for morphogenesis of neural crest-derived structures.	SOX10 ACTA1 ACTA2	5.46e-06	8	162	3	18538758
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	5.46e-06	8	162	3	20096780
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTC1	5.46e-06	8	162	3	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTC1	5.46e-06	8	162	3	20147394
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTC1	5.46e-06	8	162	3	23260110
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	WAPL ACTA1 CKAP5 ADAR PRPF40A HNRNPA2B1 TMPO DYNC1H1 KPNA1	5.71e-06	272	162	9	31010829
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	ACTA1 ACTA2 LAMA4 ACTC1	6.26e-06	26	162	4	24742657
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	VTN CAND1 ATP5PO EIF4A3 UGGT1 ACTA1 CKAP5 ACTC1 ADAR PRPF40A HNRNPA2B1 ITPR3 PDIA4 BLMH CCT5 TMPO DYNC1H1	6.48e-06	1024	162	17	24711643
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTC1	8.16e-06	9	162	3	10556093
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	8.16e-06	9	162	3	12297046
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTC1	8.16e-06	9	162	3	8892894
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTC1	8.16e-06	9	162	3	18775311
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	CUL3 AMPD1 CAND1 ATP5PO EIF4A3 UGGT1 ACTC1 ADAR HNRNPA2B1 PDIA4 ORC4 ABCB10 CCT5 DYNC1H1	8.36e-06	725	162	14	27025967
Pubmed	An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.	CUL3 CAND1 KBTBD6 GPS1 KLHL13	8.42e-06	59	162	5	19295130
Pubmed	Defining the membrane proteome of NK cells.	CUL3 GDPD1 FKBP15 CAND1 ERAP1 EIF4A3 CKAP5 ACTC1 ITGA1 MED1 ADAR PRPF40A HNRNPA2B1 ITPR3 KIF15 TMPO ADPGK DYNC1H1	9.42e-06	1168	162	18	19946888
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	CAND1 ATP5PO EIF4A3 ACTA2 CKAP5 ACTC1 MTERF4 ADAR PRPF40A HNRNPA2B1 PDIA4 CCT5 TMPO DYNC1H1 KPNA1	1.10e-05	847	162	15	35235311
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTC1	1.16e-05	10	162	3	1907279
Pubmed	Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo.	SOX10 ACTA2 TBX1	1.16e-05	10	162	3	15996652
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	1.16e-05	10	162	3	21749862
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTC1	1.16e-05	10	162	3	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTC1	1.16e-05	10	162	3	23575248
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTC1	1.59e-05	11	162	3	30962377
Pubmed	PRDM16 regulates arterial development and vascular integrity.	ACTA2 NR2F2 HEY2	1.59e-05	11	162	3	37324380
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTC1	1.59e-05	11	162	3	23294842
Pubmed	CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.	CUL3 KBTBD6 KBTBD7	1.59e-05	11	162	3	25684205
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTC1	1.59e-05	11	162	3	19639585
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CUL3 CAND1 EBF3 EIF4A3 CKAP5 MED1 ADAR HNRNPA2B1 PDIA4 BLMH RBM12 RESF1 CCT5 KLF5 TMPO SMS DYNC1H1	1.69e-05	1103	162	17	34189442
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	2.12e-05	12	162	3	31042497
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTC1	2.12e-05	12	162	3	23071112
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	2.16e-05	2	162	2	20706863
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	2.16e-05	2	162	2	3023046
Pubmed	Impact of Hey2 and COUP-TFII on genes involved in arteriovenous differentiation in primary human arterial and venous endothelial cells.	NR2F2 HEY2	2.16e-05	2	162	2	23744056
Pubmed	The microtubule-associated protein tumor overexpressed gene binds to the RNA trafficking protein heterogeneous nuclear ribonucleoprotein A2.	CKAP5 HNRNPA2B1	2.16e-05	2	162	2	15703215
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	2.16e-05	2	162	2	3075543
Pubmed	Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.	ACTA1 ACTC1	2.16e-05	2	162	2	19468071
Pubmed	alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.	ACTA1 ACTC1	2.16e-05	2	162	2	1893870
Pubmed	Cullin3 is a KLHL10-interacting protein preferentially expressed during late spermiogenesis.	CUL3 KLHL10	2.16e-05	2	162	2	16162871
Pubmed	Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.	ACTA2 ACTC1	2.16e-05	2	162	2	10686609
Pubmed	A Cul3-based E3 ligase regulates mitosis and is required to maintain the spindle assembly checkpoint in human cells.	CUL3 KLHL13	2.16e-05	2	162	2	18075312
Pubmed	A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.	ACTA1 ACTC1	2.16e-05	2	162	2	2731651
Pubmed	A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.	ACTA1 ACTC1	2.16e-05	2	162	2	6897014
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	CUL3 WAPL CAND1 EBF1 ITPR3 CCT5 DNM1 ESPL1 DYNC1H1	2.19e-05	322	162	9	26514267
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FKBP15 IQSEC3 CKAP5 SNX19 PLEKHG1 STARD9 KLHL13 PACS2 CAMTA1 DYNC1H1	2.30e-05	407	162	10	12693553
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX10 ZBTB38 EBF3 E4F1 EBF1 TEAD1 DMBX1 NR2F2 GLI2 KLF5 HEY2 DLX2 CAMTA1 TBX1 TP73	2.46e-05	908	162	15	19274049
Pubmed	Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.	SOX10 ACTC1 TBX1	2.74e-05	13	162	3	24821700
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF3 EBF1 TP73	2.74e-05	13	162	3	22421355
Pubmed	Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.	ACTA1 ACTA2 ACTC1	2.74e-05	13	162	3	18400219
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	CUL3 CAND1 ADAMTS1 UGGT1 ACTA2 CKAP5 ACTC1 ADAR PRPF40A HNRNPA2B1 AKAP12 PDIA4 BLMH CCT5 TMPO DYNC1H1 KPNA1	2.83e-05	1149	162	17	35446349
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	ACTA1 ACTA2 ACTC1	3.48e-05	14	162	3	21923909
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CUL3 SDK2 WAPL CAND1 KIF26A EIF4A3 RBM12 CCT5 ZBTB5 ESPL1 ACAP3	4.12e-05	529	162	11	14621295
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	DOCK3 MICAL1 ZBTB38 SLC38A9 TEAD1 ITPR3 PDIA4	4.22e-05	198	162	7	20881960
Pubmed	Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.	ACTA1 ACTA2 ACTC1	4.33e-05	15	162	3	24598388
Pubmed	Serum response factor is required for sprouting angiogenesis and vascular integrity.	ACTA1 ACTA2 ITGA1 HEY2	4.86e-05	43	162	4	18804439
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	WAPL TDH CKAP5 CCT5 GLI2 TMPO DYNC1H1	4.94e-05	203	162	7	22083510
Pubmed	Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.	EBF1 GLI2 DLX2	5.31e-05	16	162	3	15647317
Pubmed	Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.	ACTA1 ACTA2 ACTC1	5.31e-05	16	162	3	16638982
Pubmed	Serum response factor is essential for mesoderm formation during mouse embryogenesis.	ACTA1 ACTA2 ACTC1	5.31e-05	16	162	3	9799237
Pubmed	Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad.	SOX10 ACTA1 ACTA2	5.31e-05	16	162	3	18397758
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	CUL3 UGGT1 KLHL13	5.31e-05	16	162	3	28619731
Pubmed	CAND1 enhances deneddylation of CUL1 by COP9 signalosome.	CUL3 CAND1 GPS1	5.31e-05	16	162	3	16036220
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	CAND1 ATP5PO UGGT1 ACTA2 HNRNPA2B1 CCT5 DYNC1H1	6.12e-05	210	162	7	26217791
Pubmed	Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.	ACTA1 ACTA2 ACTC1	6.43e-05	17	162	3	17360745
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	ACTA1 ACTA2 ACTC1	6.43e-05	17	162	3	8997639
Interaction	FBXL17 interactions	CUL3 MICAL1 KLHL10 KBTBD6 KBTBD8 DVL2 KBTBD7 KLHL13	2.98e-07	85	155	8	int:FBXL17
Interaction	PXDNL interactions	CUL3 KLHL10 GPS1 KBTBD7	1.19e-05	19	155	4	int:PXDNL
GeneFamily	Actins	ACTA1 ACTA2 ACTC1	3.98e-06	6	107	3	929
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL10 ZBTB38 KBTBD6 KBTBD8 KBTBD7 KLHL13 ZBTB5	1.48e-05	134	107	7	861
GeneFamily	Bestrophins	BEST3 BEST4	2.07e-04	4	107	2	866
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	CAND1 KIF26A EBF3 FAT3 ACTA1 ACTA2 LAMA4 ACTC1 SEMA5A TEAD1 GDF10 PCDH17 FAM193A GLI2 KLF5 CAMTA1 DNM1 CPLANE1 ARMH4	6.28e-06	806	154	19	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500	EBF3 FAT3 ACTA1 ACTA2 LAMA4 ACTC1 SEMA5A PCDH17 FAM193A KLF5 DNM1 CPLANE1 ARMH4	8.86e-06	407	154	13	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500	CAND1 ACTA2 LAMA4 ACTC1 SEMA5A ITGA1 TEAD1 GDF10 PCDH17 VPS13A SORCS3 CPLANE1	3.09e-05	393	154	12	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_100	ACTA2 ACTC1 EBF1 ITGA1 OR51E1 HEY2	4.11e-05	87	154	6	gudmap_kidney_P0_JuxtaGlom_Ren1_100
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_100	ACTA2 EBF1 ITGA1 OR51E1	4.76e-05	28	154	4	gudmap_kidney_P0_JuxtaGlom_Ren1_k3_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	FAT3 ACTA2 ACTC1 MUC16 NT5DC3 NR2F2 GLI2 KLHL13 SORCS3 DNM1 ARMH4	9.07e-05	373	154	11	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	KIF26A FAT3 LAMA4 SEMA5A TEAD1 GDF10 PCDH17 FAM193A DNM1 CPLANE1	9.66e-05	312	154	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500	FAT3 LAMA4 SEMA5A PCDH17 FAM193A DNM1 CPLANE1	1.09e-04	149	154	7	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	KBTBD6 FAT3 ACTA2 MUC16 SEMA5A TBC1D8B KBTBD7 NR2F2 PDIA4 STARD9 GLI2 KLHL13 GMPR DNM1 ZMAT1 ARMH4	1.50e-04	768	154	16	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	ACTA1 THEM5 LAMA4 ACTC1 SEMA5A KBTBD7 PCDH17 PLEKHG1 FAM193A GLI2 KLF5 VPS13A HEY2 DLX2 DNM1 CPLANE1	1.53e-04	769	154	16	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_200	EBF3 ASAH2 LAMA4 EBF1 PCDH17 ARHGAP18	2.03e-04	116	154	6	gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k3_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	FAT3 ACTA2 MUC16 TBC1D8B NR2F2 GLI2 ARMH4	2.05e-04	165	154	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS1 FAT3 ACTA2 LAMA4 SEMA5A EBF1 PMEPA1 GLI2 KLHL13 HEY2	1.82e-09	186	163	10	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS1 FAT3 ACTA2 LAMA4 SEMA5A EBF1 PMEPA1 GLI2 KLHL13 HEY2	2.35e-09	191	163	10	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 ACTA2 SEMA5A EBF1 ITGA1 NR2F2 OR51E1 APOL5 HEY2	3.00e-08	186	163	9	1e3ab663e4756975db6d802b2c6c054a94a79393
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA1 ACTA2 EBF1 ITGA1 PMEPA1 NR2F2 OR51E1 HEY2 KCNS3	3.78e-08	191	163	9	239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 KLHL13 HEY2	3.78e-08	191	163	9	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 FAT3 LAMA4 SEMA5A GDF10 NR2F2 ABCA6 GLI2 SORCS3	3.95e-08	192	163	9	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	Pericytes\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ACTA2 LAMA4 ACTC1 EBF1 ITGA1 MYRFL AKAP12 HEY2	3.95e-08	192	163	9	057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 FAT3 LAMA4 SEMA5A GDF10 NR2F2 ABCA6 GLI2 SORCS3	4.32e-08	194	163	9	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 EBF1 ITGA1 PMEPA1 NR2F2 OR51E1 HEY2 KCNS3	4.51e-08	195	163	9	d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	4.51e-08	195	163	9	9b3fa1d42ec5aa2911f27a99cd8b57714c6bd604
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	4.93e-08	197	163	9	b7e399b8e1a1ffc2b359f14929f199b93d9bbcce
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	EBF3 ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	5.14e-08	198	163	9	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 NR2F2 AKAP12 ABCA6 SORCS3	5.37e-08	199	163	9	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Parenchyma_COVID-19-Stromal-TX-Smooth_muscle-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 MYRFL NR2F2 OR51E1 HEY2	5.37e-08	199	163	9	c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 MYRFL NR2F2 OR51E1 HEY2	5.37e-08	199	163	9	78b245d40c1e169ff2d26907b63d732e34529c5f
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 MYRFL NR2F2 OR51E1 HEY2	5.37e-08	199	163	9	8e1e95c3a4b856415af208be6ad977e575bac189
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	ADAMTS1 FAT3 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	5.37e-08	199	163	9	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ACTA2 LAMA4 SEMA5A EBF1 ITGA1 MYRFL NR2F2 AKAP12	5.37e-08	199	163	9	7c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 NR2F2 AKAP12 ABCA6 SORCS3	5.61e-08	200	163	9	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 NR2F2 AKAP12 ABCA6 SORCS3	5.61e-08	200	163	9	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 ACTA1 ACTC1 BEST3 CPT1B PTPRQ TBX1 TP73	1.94e-07	167	163	8	d78356bf0c473816dbabaee51984940bd822f84e
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 EBF1 ITGA1 PMEPA1 ETV3L NR2F2 HEY2 KCNS3	2.22e-07	170	163	8	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3 ADPGK	2.33e-07	171	163	8	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	OR4K13 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 PLEKHG1 TBX1	3.03e-07	177	163	8	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 MYRFL AKAP12 HEY2	3.59e-07	181	163	8	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	ACTA2 LAMA4 EBF1 PMEPA1 PCDH17 OR51E1 GLI2 APOL5	4.41e-07	186	163	8	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 AKAP12 HEY2	4.41e-07	186	163	8	c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBC1D8B HNRNPA2B1 NR2F2 KLHL13 SORCS3 DLX2 ARHGAP18	4.47e-07	127	163	7	f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	ADAMTS1 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 PLEKHG1 TBX1	4.59e-07	187	163	8	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 OR51E1 HEY2	4.98e-07	189	163	8	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 FAT3 LAMA4 SEMA5A GDF10 ABCA6 GLI2 SORCS3	4.98e-07	189	163	8	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 ACTC1 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	5.18e-07	190	163	8	a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	FAT3 ACTA2 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	5.18e-07	190	163	8	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 FAT3 LAMA4 SEMA5A GDF10 ABCA6 GLI2 SORCS3	5.39e-07	191	163	8	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 SEMA5A EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	5.84e-07	193	163	8	47d189bac0ef4df2f5c6dd987e46aca85bd7e2af
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SOX10 ADAMTS1 VEPH1 LAMA4 SEMA5A AKAP12 HEY2 GMPR	5.84e-07	193	163	8	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EBF3 SEMA5A EBF1 TBC1D8B AKAP12 ABCA6 KLHL13 DNM1	6.07e-07	194	163	8	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	metastatic_Brain-Fibroblasts-Pericytes\|metastatic_Brain / Location, Cell class and cell subclass	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2 OR51E1 HEY2	6.07e-07	194	163	8	d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	6.07e-07	194	163	8	a7731378f44ca1a229311686caf5740c742d21ba
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 EBF1 ITGA1 TEAD1 NR2F2 OR51E1 HEY2	6.07e-07	194	163	8	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	6.31e-07	195	163	8	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	6.31e-07	195	163	8	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS1 FAT3 ACTA2 LAMA4 EBF1 ITGA1 NR2F2 ABCA6	6.31e-07	195	163	8	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 AKAP12 ABCA6 GLI2	6.31e-07	195	163	8	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	(5)_Fibroblast-K_(Pericytes)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ADAMTS1 ACTA1 ACTA2 ACTC1 EBF1 ITGA1 MYRFL HEY2	6.56e-07	196	163	8	e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCell	IPF-Stromal-Pericyte\|IPF / Disease state, Lineage and Cell class	ADAMTS1 ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2 AKAP12	6.56e-07	196	163	8	8b6ff47ce5291d223f5e639fc45cd9267f418256
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ACTA1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 AKAP12	6.56e-07	196	163	8	70b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 PMEPA1 NR2F2 OR51E1	6.56e-07	196	163	8	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	6.56e-07	196	163	8	9a420a4eb46cb554bec641726fea5398ff60f630
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 PMEPA1 NR2F2 OR51E1	6.56e-07	196	163	8	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ACTA1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 AKAP12	6.56e-07	196	163	8	ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 ACTA2 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	6.56e-07	196	163	8	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 ACTA2 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	6.56e-07	196	163	8	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 SEMA5A EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	6.81e-07	197	163	8	452be45f4aac8459dd860493171f5f715368d663
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	6.81e-07	197	163	8	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	6.81e-07	197	163	8	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	6.81e-07	197	163	8	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 NR2F2 ABCA6 SORCS3	7.35e-07	199	163	8	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 AKAP12 ABCA6 SORCS3	7.35e-07	199	163	8	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 AKAP12 ABCA6 GLI2	7.35e-07	199	163	8	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2 AKAP12	7.35e-07	199	163	8	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	proximal-3-mesenchymal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 ACTA2 LAMA4 EBF1 ITGA1 GDF10 NR2F2 ABCA6	7.64e-07	200	163	8	94250991f78ea56810412d00a4bb645eb975478c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 AKAP12 ABCA6 SORCS3	7.64e-07	200	163	8	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SDK2 ADAMTS1 LAMA4 SEMA5A GDF10 AKAP12 ABCA6 SORCS3	7.64e-07	200	163	8	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SDK2 ADAMTS1 FAT3 LAMA4 ITGA1 GDF10 NR2F2 ABCA6	7.64e-07	200	163	8	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SDK2 ADAMTS1 FAT3 LAMA4 ITGA1 GDF10 NR2F2 ABCA6	7.64e-07	200	163	8	a510deaada669e690329183e18df02870bd204b3
ToppCell	proximal-mesenchymal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 ACTA2 LAMA4 EBF1 ITGA1 GDF10 NR2F2 ABCA6	7.64e-07	200	163	8	29f3a5c85404c6537d6405d599ebae281e0d4d4f
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 FAT3 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	7.64e-07	200	163	8	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 FAT3 ACTA2 LAMA4 ACTC1 EBF1 ITGA1 AKAP12	7.64e-07	200	163	8	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SDK2 ADAMTS1 FAT3 LAMA4 ITGA1 GDF10 NR2F2 ABCA6	7.64e-07	200	163	8	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF26A THEM5 LAMA4 NR2F2 AKAP12 PLEKHG1 TBX1	2.69e-06	166	163	7	5ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF26A THEM5 LAMA4 NR2F2 AKAP12 PLEKHG1 TBX1	2.69e-06	166	163	7	6bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	ADAMTS1 ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2	3.28e-06	171	163	7	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	LAMA4 EBF1 ITGA1 NR2F2 AKAP12 PLEKHG1 TBX1	3.54e-06	173	163	7	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SEMA5A EBF1 ITGA1 PMEPA1 PCDH17 HEY2	4.11e-06	177	163	7	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SEMA5A EBF1 ITGA1 PMEPA1 PCDH17 HEY2	4.11e-06	177	163	7	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	4.27e-06	178	163	7	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	COPD-Stromal-SMC\|COPD / Disease state, Lineage and Cell class	ADAMTS1 ACTA2 ACTC1 EBF1 NR2F2 AKAP12 HEY2	4.43e-06	179	163	7	5c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCell	Control-Stromal-SMC\|Control / Disease state, Lineage and Cell class	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 AKAP12	4.43e-06	179	163	7	1378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACTA2 LAMA4 EBF1 ITGA1 NR2F2 OR51E1 KCNS3	4.60e-06	180	163	7	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	ADAMTS1 FAT3 ACTA2 LAMA4 EBF1 ITGA1 AKAP12	4.60e-06	180	163	7	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 FAT3 ITPRID1 NR2F2 ABCA6 GLI2 SORCS3	4.60e-06	180	163	7	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 KIF26A LAMA4 ITGA1 PCDH17 PLEKHG1 HEY2	4.77e-06	181	163	7	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	4.94e-06	182	163	7	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS1 EBF3 SEMA5A EBF1 ITGA1 NR2F2 PLEKHG1	4.94e-06	182	163	7	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LAMA4 EBF1 ITGA1 AKAP12 ABCA6 GLI2	4.94e-06	182	163	7	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ACTA1 ACTA2 ACTC1 EBF1 MYRFL HEY2	5.12e-06	183	163	7	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	ADAMTS1 ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2	5.12e-06	183	163	7	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	Control-Stromal-SMC\|World / Disease state, Lineage and Cell class	ADAMTS1 ACTA2 ACTC1 EBF1 ITGA1 NR2F2 AKAP12	5.31e-06	184	163	7	88b1a4c9a96a99fc3a39f7a2c3d0838739606f3e
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	LAMA4 EBF1 ITGA1 NR2F2 AKAP12 PLEKHG1 TBX1	5.50e-06	185	163	7	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SOX10 WDR64 SLC22A11 ACTC1 CSMD2 PMEPA1 DLX2	5.50e-06	185	163	7	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	LAMA4 EBF1 ITGA1 NR2F2 AKAP12 PLEKHG1 TBX1	5.50e-06	185	163	7	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 LAMA4 SEMA5A EBF1 ITGA1 NR2F2 HEY2	5.70e-06	186	163	7	6568358812f0ca4e0161a1a1b29682fbced35c79
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA4 ITGA1 TEAD1 CPT1B MLF1 ZBTB5 KCNS3	5.70e-06	186	163	7	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 SEMA5A EBF1 ITGA1 ETV3L NR2F2 APOL5	5.70e-06	186	163	7	0b2ce9b8a4382d583240647217ad5e2d3fa555c1
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA4 ITGA1 TEAD1 CPT1B MLF1 ZBTB5 KCNS3	5.70e-06	186	163	7	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA4 ITGA1 TEAD1 CPT1B MLF1 ZBTB5 KCNS3	5.70e-06	186	163	7	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SEMA5A EBF1 ITGA1 PMEPA1 GLI2 HEY2	5.90e-06	187	163	7	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 EBF1 ITGA1 NR2F2 OR51E1 HEY2 KCNS3	5.90e-06	187	163	7	6820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 ACTA2 SEMA5A EBF1 ITGA1 NR2F2 APOL5	5.90e-06	187	163	7	b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	7.96e-06	8	156	3	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	7.96e-06	8	156	3	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	7.96e-06	8	156	3	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	7.96e-06	8	156	3	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.69e-05	10	156	3	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.69e-05	10	156	3	DOID:13832 (implicated_via_orthology)
Disease	uncharacterized protein C17orf78 measurement	VTN QSOX1	8.30e-05	3	156	2	EFO_0802191
Disease	colorectal health	ADAMTS1 PKD1L1 SEMA5A TEAD1 SORCS3 KCNS3 ESPL1	1.01e-04	201	156	7	EFO_0008460
Disease	Mammary Carcinoma, Human	ADAMTS1 WNT10B ACTA2 TRMT11 GDF10 ADAR AKAP12 CCT5 HEY2 RIC8A TP73	1.17e-04	525	156	11	C4704874
Disease	Mammary Neoplasms, Human	ADAMTS1 WNT10B ACTA2 TRMT11 GDF10 ADAR AKAP12 CCT5 HEY2 RIC8A TP73	1.17e-04	525	156	11	C1257931
Disease	Mammary Neoplasms	ADAMTS1 WNT10B ACTA2 TRMT11 GDF10 ADAR AKAP12 CCT5 HEY2 RIC8A TP73	1.21e-04	527	156	11	C1458155
Disease	Breast Carcinoma	ADAMTS1 WNT10B ACTA2 TRMT11 GDF10 ADAR AKAP12 CCT5 HEY2 RIC8A TP73	1.44e-04	538	156	11	C0678222
Disease	asparagine measurement, amino acid measurement	KIF26A ASPG	1.65e-04	4	156	2	EFO_0005134, EFO_0009766
Disease	Hypertrophic Cardiomyopathy	ACTA1 ACTC1 HEY2 TMPO	2.39e-04	57	156	4	C0007194
Disease	Colorectal Carcinoma	AMPD1 ITPRID1 AKAP12 CNPPD1 ABCB10 SULT2B1 ABCA6 GUCY2C KLF5 VPS13A DIP2C TBX1	3.73e-04	702	156	12	C0009402
Disease	Malignant neoplasm of breast	MICAL1 ADAMTS1 WNT10B ACTA2 KBTBD8 TRMT11 GDF10 ADAR AKAP12 ABCB10 CCT5 HEY2 DIP2C RIC8A TP73	5.98e-04	1074	156	15	C0006142
Disease	colorectal adenoma	FAT3 CSMD2 FAM193A	7.04e-04	33	156	3	EFO_0005406
Disease	Primary dilated cardiomyopathy	LAMA4 ACTC1 TMPO	7.69e-04	34	156	3	cv:C0007193
Disease	epilepsy (is_implicated_in)	POLG TBX1	9.76e-04	9	156	2	DOID:1826 (is_implicated_in)
Disease	free cholesterol in medium LDL measurement	ITGA1 ABCA6 PCSK9	1.24e-03	40	156	3	EFO_0022268
Disease	nucleus accumbens volume change measurement	MUC16 ITPRID1	1.48e-03	11	156	2	EFO_0021493
Disease	serum metabolite measurement	ERAP1 ASPG PKD1L1 VEPH1 SLC22A11 CKAP5 THEM5 TEAD1 HEY2 DIP2C SORCS3 PCSK9 ARMH4	1.59e-03	945	156	13	EFO_0005653
Disease	Familial dilated cardiomyopathy	LAMA4 ACTC1 TMPO	1.64e-03	44	156	3	C0340427
Disease	multisite chronic pain	PMEPA1 ITPR3 SORCS3 OR52W1	1.65e-03	95	156	4	EFO_0010100
Disease	smoking cessation	CUL3 KIF26A VEPH1 PMEPA1 NR2F2 ITPR3 CAMTA1	1.77e-03	325	156	7	EFO_0004319
Disease	hemoglobin A1 measurement	CUL3 ZBTB38 SLC38A9 EBF1 SLC25A37 PLEKHG1 ABCB10 VPS13A RIC8A	1.86e-03	520	156	9	EFO_0007629
Disease	Cardiomyopathy	LAMA4 ACTC1 TMPO	1.98e-03	47	156	3	cv:C0878544
Disease	Cardiomyopathy, Dilated	ACTA1 ACTC1 TMPO	2.11e-03	48	156	3	C0007193
Disease	phospholipids in medium LDL measurement	ITGA1 ABCA6 PCSK9	2.23e-03	49	156	3	EFO_0022183
Disease	free cholesterol in LDL measurement	ITGA1 ABCA6 PCSK9	2.37e-03	50	156	3	EFO_0022266
Disease	free cholesterol in large LDL measurement	ITGA1 ABCA6 PCSK9	2.51e-03	51	156	3	EFO_0022176
Disease	phospholipids in very small VLDL measurement	SULT2B1 ABCA6 PCSK9	2.51e-03	51	156	3	EFO_0022300
Disease	schizophrenia, intelligence, self reported educational attainment	FAM184A FAT3 TEAD1 PMEPA1 SNX19 PCDH17 SORCS3	2.52e-03	346	156	7	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	Schizophrenia	SOX10 ARHGAP32 GPS1 CSMD2 PCDH17 CNPPD1 KLF5 KCNS3 ARHGAP18 DNM1 TBX1 KPNA1	2.64e-03	883	156	12	C0036341
Disease	total lipids in medium LDL	ITGA1 ABCA6 PCSK9	2.65e-03	52	156	3	EFO_0022180
Disease	total lipids in LDL measurement	ITGA1 ABCA6 PCSK9	2.65e-03	52	156	3	EFO_0022308
Disease	myocardial infarction	EIF4A3 VEPH1 ITGA1 PMEPA1 PLEKHG1 PCSK9 ARMH4	2.68e-03	350	156	7	EFO_0000612
Disease	Alobar Holoprosencephaly	GLI2 DISP1	2.79e-03	15	156	2	C0431363
Disease	phospholipids in large LDL measurement	ITGA1 ABCA6 PCSK9	2.80e-03	53	156	3	EFO_0022174
Disease	free cholesterol in small LDL measurement	ITGA1 ABCA6 PCSK9	2.80e-03	53	156	3	EFO_0022271
Disease	Lobar Holoprosencephaly	GLI2 DISP1	3.17e-03	16	156	2	C0431362
Disease	Semilobar Holoprosencephaly	GLI2 DISP1	3.17e-03	16	156	2	C0751617
Disease	Drug habituation	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0013170
Disease	Drug abuse	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0013146
Disease	Prescription Drug Abuse	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C4316881
Disease	Substance-Related Disorders	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0236969
Disease	Drug Use Disorders	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0013222
Disease	Drug Dependence	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C1510472
Disease	antihyperlipidemic drug use measurement	PMEPA1 ABCA6 RTL9 PCSK9	3.30e-03	115	156	4	EFO_0803367
Disease	Substance Dependence	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0038580
Disease	Substance Use Disorders	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FKBP15 FAM184A QSOX1 OR51E1	3.30e-03	115	156	4	C0029231
Disease	Substance abuse problem	FKBP15 FAM184A QSOX1 OR51E1	3.40e-03	116	156	4	C0740858
Disease	total lipids in large LDL	ITGA1 ABCA6 PCSK9	3.44e-03	57	156	3	EFO_0022163
Disease	cholesterol in large LDL measurement	ITGA1 ABCA6 PCSK9	3.44e-03	57	156	3	EFO_0021901
Disease	Holoprosencephaly	GLI2 DISP1	3.59e-03	17	156	2	C0079541
Disease	phospholipids in LDL measurement	ITGA1 ABCA6 PCSK9	3.61e-03	58	156	3	EFO_0022294
Disease	Colorectal Neoplasms	CNPPD1 ABCB10 SULT2B1 ABCA6 GUCY2C KLF5	3.65e-03	277	156	6	C0009404
Disease	phospholipids in small LDL measurement	ITGA1 ABCA6 PCSK9	3.79e-03	59	156	3	EFO_0022297
Disease	bone mineral content measurement	BEST3 PDIA4 GUCY2C DIP2C	5.10e-03	130	156	4	EFO_0007621
Disease	age at initiation of smoking	CUL3 ITPR3 SORCS3	5.20e-03	66	156	3	EFO_0021784

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPTMDHVVEAGFMTT	BEST3	151	Q8N1M1
FPTMEHVVDAGFMSQ	BEST4	151	Q8NFU0
AAGSMMQTHGDFDVA	BBS4	241	Q96RK4
FSHDLSNGAMNMLEV	ADPGK	231	Q9BRR6
SEGGASTMAYMHVAE	CAMTA1	836	Q9Y6Y1
STMAYMHVAEVVSAA	CAMTA1	841	Q9Y6Y1
VFSHSEMMGVTLNST	CSMD2	1166	Q7Z408
MESAGIHETTYNSIM	ACTA1	271	P68133
ESQVHMMAAAVADGT	AKAP12	886	Q02952
EMSQTAQVSHEGMEG	ARMH4	341	Q86TY3
NEMELAHSSFSEMQT	ABCA6	811	Q8N139
MESAGIHETTYNSIM	ACTA2	271	P62736
MSDMTKLHQAVAAGD	ANKRD66	6	B4E2M5
MGSAHMTVGELSSFL	ABCB10	421	Q9NRK6
ILDSMLSFMHAQSSF	ACAP3	186	Q96P50
AGALTHLMTAFMIAD	AMPD1	576	P23109
MTGVFDSLVADMHST	DLX2	1	Q07687
SAMAMAALTTFVAGA	DISP1	1081	Q96F81
GENNFTDTMRHMLSS	FAM193A	181	P78312
GLSVHTDMASVTKAM	DVL2	416	O14641
TAQLAGHSMDYSQEM	FAM184A	26	Q8NB25
TQGVVSAFSTMMSVH	ATP5PO	121	P48047
VSVHGMPFSAMENDV	RBM12	306	Q9NTZ6
MASDQMARVFADVHS	PCDH17	1091	O14917
DCASHFEQMAAASMH	QSOX1	451	O00391
HASPMSADRVVAFMD	NR2F2	276	P24468
ETMLVADQSMAEFHG	ADAMTS1	261	Q9UHI8
HNGSYEISVLMMGNS	GUCY2C	31	P25092
MSEMSSFLHIGDIVS	ITPR3	1	Q14573
TASHPFMTAVDLMEA	ORC4	291	O43929
ATQREAAAMTSSMAH	HEY2	161	Q9UBP5
MTHGFSQLDVTTLMS	MUC16	5006	Q8WXI7
SQGFSHSQMTALMSR	MUC16	9111	Q8WXI7
MFFVHALTAMESGVL	OR52W1	106	Q6IF63
VNFLGTLSMHASMFV	GPR82	91	Q96P67
TFTMMGPSESDNFSH	KIF15	116	Q9NS87
AAFDEVKMAAHTMGN	TMPO	631	P42166
LGFMVTHVTEMQDSF	ITPRID1	566	Q6ZRS4
VVIHGTDTMAFAASM	ASPG	111	Q86U10
ENGSDSFMHSMDPQL	DNM1	641	Q05193
EFASHGMQNMTVVIS	ASAH2	556	Q9NR71
MLVFGGNTHNDTSMS	ATRN	566	O75882
KMREANFTVSSMHGD	EIF4A3	296	P38919
MADRAEMFSLSTFHS	MAPK8IP2	1	Q13387
SMQDSEMILTATFHF	GDF10	121	P55107
ISESDMHVSQMAISF	CAND1	701	Q86VP6
IAHMVMGTTNQFSTR	ERAP1	871	Q9NZ08
SQAAAHVAGIAAMML	PCSK9	386	Q8NBP7
LNGTDMFHMVQSAGV	FAT2	2006	Q9NYQ8
LQMFAIHSLSGMEST	OR51E1	101	Q8TCB6
LHGFSFMESSVLLAM	OR51Q1	106	Q8NH59
VGFVHSSSQMAFMLT	OR4K13	151	Q8NH42
HGFNVAQTMFTLLMT	PDE6B	561	P35913
MHRMAAAFNTTVAAL	GPS1	386	Q13098
SGDMASFLMTEARQH	FKBP15	501	Q5T1M5
AGGAHSFETAMMEST	VEPH1	651	Q14D04
SMHMAISGLSSFQRS	POLG	296	P54098
ASAMGINTAHQTGMI	MYRFL	486	Q96LU7
EMMDLQHGSLFFSTS	LDHC	61	P07864
AHVMMVTCFDISVAA	KIF26A	1856	Q9ULI4
HGQPDVSAFDFTSMM	MICAL1	356	Q8TDZ2
HAMAAMPSSQETAEA	GLI2	1401	P10070
TMAAFQHAVKIGTDM	GDPD1	56	Q8N9F7
AMCVHSMSEFQNEDG	KCNS3	201	Q9BQ31
TGGMYESQQASVTMH	KBTBD7	101	Q8WVZ9
NSSHFMGTDKMASVF	OR5B12	261	Q96R08
AASTGGSHLTAVAMM	OR5C1	241	Q8NGR4
TLAAGSISMAEVMQH	PACS2	131	Q86VP3
ASFEMEMSQTGFSAH	ITGA1	371	P56199
NHVDVLFSGRISMAM	ARHGAP32	561	A7KAX9
AHSGTLMMAFRDVTV	IQSEC3	476	Q9UPP2
MHRLMGVNSTAAAAA	PMEPA1	1	Q969W9
GMTASEMIICFDAAH	KBTBD8	281	Q8NFY9
FTEHMISVSAFTIMG	PTPRQ	581	Q9UMZ3
TTMSTMAAAEAAAAV	PRPF40A	266	O75400
TTMDITHDGFGFMLA	TM7SF2	246	O76062
ISAGEAHSMALSMSG	HERC5	196	Q9UII4
DSSMDVFHLEGMTTS	TP73	46	O15350
VFHLEGMTTSVMAQF	TP73	51	O15350
SASSFAQGISMEAMS	INO80C	46	Q6PI98
AMSGHIDQFLIATFM	CKAP5	1576	Q14008
HVSSSDLFLISMMVA	CNPPD1	116	Q9BV87
GQELTDHMGMTASYT	ESPL1	446	Q14674
MEMESAAASTRFHQP	KLHL10	1	Q6JEL2
TDDAFPVHRVMMASA	KLHL13	101	Q9P2N7
SHASSEAGNMVMLGD	DOCK3	1686	Q8IZD9
AMKALHGEATNSMAS	ADAR	676	P55265
MLQDDNTSAGLHFMA	CPLANE1	2531	Q9H799
KAEENGSNSFMHSMV	DNM1P34	11	Q6PK57
VNGYSLHAMNSLSAM	DMBX1	6	Q8NFW5
MHTTGSMEVSAESNR	BPI	391	P17213
DMSISNTTMDEFRQH	CUL3	476	Q13618
MVKEAMDSGLHFTQS	FAT3	1971	Q8TDW7
MLAGVKMSHAATSAF	DIP2C	1146	Q9Y2E4
NTSVHAGMMGVNSFS	EBF1	426	Q9UH73
GESLMTHAMTFTAVS	BLMH	366	Q13867
AATGIMSDQMQRHSY	MARVELD1	111	Q9BSK0
HTVMTMGSDFQYENA	MAN2B1	311	O00754
ATGTFDNEIVMMNHV	MAST3	161	O60307
HMFVSTNLGESFMSI	DYNC1H1	4006	Q14204
MEGAMAVRVTAAHTA	E4F1	1	Q66K89
DTVGTFEMAAVMSQH	GMPR	56	P36959
HTGMMGVNSFSSQLA	EBF3	431	Q9H4W6
SMLFAHQAMVEQLTG	ETV3L	166	Q6ZN32
THMLDNGSAVSTNMT	SLC22A11	51	Q9NSA0
GHSEMMSLDESSFPA	SDK2	1976	Q58EX2
MANMNSDSRHLGTSE	SLC38A9	1	Q8NBW4
TAAFAAAISMVVAMA	NKG7	96	Q16617
FGDSSGVEMRLHNMS	PKD1L1	326	Q8TDX9
TGSMNVIHMLESFTF	DYRK3	266	O43781
ESTAFVQAMMEGSHT	CPT1B	611	Q92523
TGGMYESQQASVTMH	KBTBD6	101	Q86V97
FNMSMSIKDRHESVG	MED1	576	Q15648
MMDNHSSATEFHLLG	OR9A2	1	Q8NGT5
MMFDGQSAVEVHSRT	LAMA4	836	Q16363
ELMRASASGHMSTAQ	RTL9	926	Q8NET4
SASGHMSTAQTTAMV	RTL9	931	Q8NET4
MAAARHSTLDFMLGA	SMS	1	P52788
NTSMDAGLSFIMANH	TRMT11	196	Q7Z4G4
VAHSTFSAMKANTMS	SULT2B1	241	O00204
QEMFGSMFHAETLTA	SLC26A9	776	Q7LBE3
EAGMETHIMTVFGHF	SORCS3	661	Q9UPU3
GHSSSAMLMLLSVVF	SORCS3	1121	Q9UPU3
TALSMVMHNYESSGI	RESF1	736	Q9HCM1
VMSDGGFHEAQISNM	KPNA1	61	P52294
MSSLLDMGFSNAHIN	MTERF4	96	Q7Z6M4
SSHGNTMKQFMDIFS	NT5DC3	206	Q86UY8
TSASVSTHMTAGAMA	SLC25A37	41	Q9NYZ2
AAMNFQTMHNVTTET	ST3GAL5	381	Q9UNP4
DSTQVHMISAAMAGF	SLC25A36	116	Q96CQ1
HMISAAMAGFTAITA	SLC25A36	121	Q96CQ1
TNDGATILSMMDVDH	CCT5	71	P48643
ITDSMVAAAMAHRGV	MRI1	226	Q9BV20
SHMMDVQGSTQDSAI	PDIA4	371	P13667
HLSVMAAQSVYDTSM	STARD9	4616	Q9P2P6
LSMGMSADFQHAVEV	PLPBP	221	O94903
HGDSTEFMGVNMDVI	RIC8A	296	Q9NPQ8
FNMFHMIAVGLSSSI	SEMA5A	966	Q13591
MESAGIHETTYNSIM	ACTC1	271	P68032
NLMSTVHSDEAGMLS	APOL5	61	Q9BWW9
STMSEGAQTMIEHNS	STK3	341	Q13188
EQQSDMVAMGTHANA	TEX13D	181	A0A0J9YY54
QLMMNGATSSFENGH	ZBTB5	561	O15062
VADFGLITMTNTFHM	VPS13A	1231	Q96RL7
MAHFVQGTSRMIAAE	TNIP3	1	Q96KP6
SMAEVDAAMAARPHS	HNRNPA2B1	71	P22626
MLANLQATSEDMHGF	SPATA31A1	966	Q5TZJ5
QLTEHMTDMTFFSSV	TBC1D8B	631	Q0IIM8
FAHGGSLAAMMDETF	THEM5	156	Q8N1Q8
FHERSSNMLSMENVG	SPATA31D1	756	Q6ZQQ2
HTDVSSFQTMDQMVS	MLF1	66	P58340
ISHEVMSNMETFDVA	SOX10	281	P56693
AHGMVAMVFKTLDDS	WAPL	696	Q7Z5K2
MSVMDSHAVAQSVLT	SNX19	146	Q92543
EFVMAAGTANTMHLL	ARHGAP18	501	Q8N392
EEMSNMFQSSGVQHH	STARD7	106	Q9NQZ5
GSFGSRMTLVSNSHM	PLEKHG1	26	Q9ULL1
MHFSTVTRDMEAFTA	TBX1	1	O43435
VIMHSNAIAAMTSSN	ZBTB38	726	Q8NAP3
HMAAMSSAQIVSATA	TEAD1	121	P28347
ESAFSFSMLAAGVMH	WNT10B	116	O00744
FSMLAAGVMHAVATA	WNT10B	121	O00744
SSLSAVFEHFAMMQR	VTN	296	P04004
MLENFALMASLGHTS	ZNF772	56	Q68DY9
AHETTAELMNTAEMF	UGGT1	506	Q9NYU2
VHAELMGETMQSRFS	TDH	196	Q8IZJ6
FQMLSLEMSGSFHSS	HSD52	26	Q0P140
YDANHGMLITGSSVM	WDR64	421	B1ANS9
SIAFTSLDMFRSHMQ	ZMAT1	181	Q5H9K5
SLDMFRSHMQGSEHQ	ZMAT1	186	Q5H9K5
MSAAMAGLNTHTSAV	KLF5	256	Q13887