Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal respiratory system morphology

GATA3 FUZ GSX2 SMPD1 BMPR2 EGR1 PRDM16 BTBD7 ACAN CIC RC3H1

3.22e-0610272911MP:0002132
MousePhenoabnormal motor neuron morphology

FUZ GBX1 ZNF106 TOP2B UNC5C

1.33e-05151295MP:0000937
MousePhenoabnormal lung morphology

FUZ SMPD1 BMPR2 EGR1 PRDM16 BTBD7 ACAN CIC RC3H1

1.59e-05767299MP:0001175
MousePhenoabnormal spinal cord morphology

FUZ GBX1 ZNF106 ACAN TOP2B UNC5C

1.89e-05278296MP:0000955
MousePhenoabnormal spinal cord grey matter morphology

FUZ GBX1 ZNF106 TOP2B UNC5C

3.18e-05181295MP:0008503
MousePhenomandible hypoplasia

GATA3 FUZ PRDM16

4.60e-0534293MP:0000460
MousePhenoabnormal Meckel's cartilage morphology

GATA3 FUZ PRDM16

8.12e-0541293MP:0005587
MousePhenoabnormal tongue morphology

GATA3 FUZ PRDM16 ACAN

9.73e-05118294MP:0000762
MousePhenodecreased submandibular gland size

PRDM16 BTBD7

1.15e-048292MP:0009520
MousePhenoabnormal choroid plexus morphology

FUZ SMPD1 PRDM16

1.30e-0448293MP:0000820
MousePhenoabnormal tela choroidea morphology

FUZ SMPD1 PRDM16

1.30e-0448293MP:0013306
MousePhenoabnormal cranial cartilage morphology

GATA3 FUZ PRDM16

1.47e-0450293MP:0030464
MousePhenopulmonary hypoplasia

FUZ PRDM16 ACAN

1.85e-0454293MP:0001178
MousePhenofacial bone hypoplasia

GATA3 FUZ PRDM16

2.18e-0457293MP:0030386
MousePhenosmall maxilla

GATA3 FUZ PRDM16

2.41e-0459293MP:0004540
MousePhenomaxilla hypoplasia

GATA3 FUZ

2.71e-0412292MP:0000457
MousePhenocleft palate

GATA3 FUZ PRDM16 ACAN TOP2B

2.88e-04289295MP:0000111
MousePhenooral cleft

GATA3 FUZ PRDM16 ACAN TOP2B

2.98e-04291295MP:0021164
MousePhenopersistent truncus arteriosus

GATA3 FUZ BMPR2

3.52e-0467293MP:0002633
MousePhenoabnormal aorticopulmonary septum morphology

GATA3 FUZ BMPR2

3.67e-0468293MP:0010650
MousePhenoaorticopulmonary septal defect

GATA3 FUZ BMPR2

3.67e-0468293MP:0010651
MousePhenoabnormal palate morphology

GATA3 FUZ PRDM16 ACAN TOP2B

4.67e-04321295MP:0003755
MousePhenoabnormal striatum morphology

FUZ GSX2 CBARP

4.90e-0475293MP:0004077
MousePhenoabnormal salivary gland morphology

PRDM16 BTBD7 PHRF1

5.30e-0477293MP:0000613
MousePhenoabnormal innervation

GATA3 ACAN TOP2B UNC5C

6.38e-04193294MP:0002184
MousePhenoneonatal lethality, complete penetrance

FUZ GSX2 PRDM16 ACAN RC3H1 TOP2B

6.77e-04534296MP:0011087
MousePhenoabnormal truncus arteriosus septation

GATA3 FUZ BMPR2

6.83e-0484293MP:0010454
MousePhenoabnormal nervous system development

GATA3 FUZ GSX2 SMPD1 EGR1 PALLD RC3H1 TOP2B UNC5C

7.12e-041257299MP:0003861
MousePhenolethality during fetal growth through weaning, complete penetrance

FUZ GSX2 BMPR2 PRDM16 PALLD BTBD7 ACAN RC3H1 TOP2B

7.63e-041269299MP:0011111
MousePhenosmall uterus

CRTC1 EGR1 PHRF1

8.90e-0492293MP:0002637
MousePhenoabnormal merocrine gland morphology

PRDM16 BTBD7 PHRF1

1.04e-0397293MP:0013544
MousePhenoabnormal respiration

GSX2 SMPD1 PRDM16 BTBD7 ACAN TOP2B

1.22e-03598296MP:0001943
Domain-

ZC3H6 RC3H1

2.54e-03403524.10.1000.10
DomainSET

SETD1B PRDM16

3.35e-0346352SM00317
DomainZnF_C3H1

ZC3H6 RC3H1

3.65e-0348352SM00356
Domainzf-CCCH

ZC3H6 RC3H1

3.80e-0349352PF00642
DomainSET_dom

SETD1B PRDM16

3.95e-0350352IPR001214
DomainSET

SETD1B PRDM16

3.95e-0350352PS50280
DomainZnf_CCCH

ZC3H6 RC3H1

5.28e-0358352IPR000571
DomainZF_C3H1

ZC3H6 RC3H1

5.28e-0358352PS50103
Domainzf-C3HC4

RFPL1 RC3H1 PHRF1

8.30e-03223353PF00097
Pubmed

A human MAP kinase interactome.

ZNF106 CRTC1 SORBS1 EGR1 RBM33 CIC

1.59e-0548639620936779
Pubmed

Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway.

ETV3 SBNO2

1.83e-05639218025162
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

GATA3 ETV3 EGR1 PRDM16 ZC3H6 BTBD7 CIC

2.86e-0580839720412781
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ZNF106 CRTC1 CBARP BMPR2 SORBS1 PALLD CIC

4.29e-0586139736931259
Pubmed

Regulation of GATA-3 expression during CD4 lineage differentiation.

GATA3 EGR1

5.48e-051039221357543
Pubmed

miRNAs control tracheal chondrocyte differentiation.

EGR1 ACAN

8.03e-051239221945074
Pubmed

Gene expression changes in the secondary palate and mandible of Prdm16(-/-) mice.

PRDM16 ACAN

9.48e-051339223149718
Pubmed

Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

GATA3 TOP2B

1.46e-041639216923961
Pubmed

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.

SCAP ACAN

1.85e-041839229899135
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FUZ BMPR2 ACAN

1.96e-0410039325807483
Pubmed

Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia.

GATA3 ACAN

2.30e-042039224385915
Pubmed

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

GSX2 UNC5C

2.54e-042139223312517
Pubmed

Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases.

GATA3 GSX2

2.79e-042239233711282
Pubmed

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2.

GSX2 GBX1

2.79e-042239233821423
Pubmed

Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons.

GATA3 UNC5C

3.33e-042439214534138
Pubmed

Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.

GSX2 GBX1

3.62e-042539223042297
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

PRDM16 ACAN

3.62e-042539229475039
Pubmed

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.

GATA3 GSX2

4.23e-042739220081190
Pubmed

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

BMPR2 ACAN

4.55e-042839219224984
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

GATA3 BMPR2

4.55e-042839223103586
Pubmed

Genetic mapping of eight SH3 domain genes on seven mouse chromosomes.

SORBS1 ACAN

4.55e-042839210087302
Pubmed

A census of human transcription factors: function, expression and evolution.

GATA3 ETV3 GSX2 GBX1 EGR1 CIC

4.87e-0490839619274049
Pubmed

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

ETV3 ACAN

4.88e-042939226097038
Pubmed

Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants.

GSX2 ACAN

5.58e-043139224014668
Pubmed

c-Jun is required for the specification of joint cell fates.

GATA3 ACAN

5.58e-043139223475960
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

GATA3 SF3A1 TOP2B NOL6

5.70e-0434139432971831
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

RBM33 SF3A1 TOP2B

6.17e-0414839332538781
Pubmed

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.

GATA3 UNC5C

6.33e-043339218480165
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

RBM33 CIC RC3H1

6.66e-0415239338360978
Pubmed

The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.

GSX2 GBX1

6.72e-043439220181579
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

RC3H1 TOP2B UNC5C PHRF1

6.83e-0435839432460013
Pubmed

β-Catenin regulates endocardial cushion growth by suppressing p21.

BMPR2 ACAN

7.12e-043539237385754
Pubmed

Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.

BMP2K EGR1

7.96e-043739222432025
Pubmed

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

GATA3 SMPD1

7.96e-043739229044125
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

SORBS1 TOP2B UNC5C

9.37e-0417139320201926
Pubmed

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

SMPD1 SCAP

9.77e-044139219878569
Cytoband22q12.2

RFPL1 SF3A1

1.13e-035839222q12.2
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1B PRDM16

9.23e-0434242487
GeneFamilyZinc fingers CCCH-type

ZC3H6 RC3H1

9.78e-043524273
GeneFamilyHOXL subclass homeoboxes

GSX2 GBX1

2.15e-0352242518
GeneFamilyRing finger proteins

RFPL1 RC3H1 PHRF1

5.56e-0327524358
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PALLD UNC5C

1.91e-02161242593
CoexpressionGSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP

GATA3 ETV3 RILP EGR1 PALLD SBNO2

4.00e-07199386M7885
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

GATA3 BMPR2 EGR1 PALLD UNC5C

5.56e-06177385M39245
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SORBS1 PRDM16 PALLD UNC5C

1.56e-05173394cb6389536195443633adb06e5f1b7483530773d1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

1.64e-05175394d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

1.64e-05175394454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMPR2 BTBD7 TOP2B

1.67e-05176394749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PRDM16 ACAN UNC5C

2.21e-051893947fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

2.21e-051893942cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PRDM16 ACAN UNC5C

2.21e-0518939406b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

2.21e-05189394127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.26e-051903942e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

GBX1 SORBS1 PRDM16 PALLD

2.26e-05190394de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.26e-0519039470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.26e-051903940028f886c789ba238c031eae5d96acaed4af8c25
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.30e-0519139404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

2.35e-05192394b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GBX1 SORBS1 ACAN UNC5C

2.35e-05192394bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

B3GNT9 EGR1 PALLD UNC5C

2.35e-05192394e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

BMPR2 EGR1 PRDM16 PALLD

2.50e-0519539456f88ce95495260360bf08f9c76cc36e395dc6a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.55e-051963941522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD ACAN UNC5C

2.55e-051963941c8294014713684b50885e638668f2ce75f357f0
ToppCellmLN-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

ETV3 SETD1B BMP2K PALLD

2.76e-052003943813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBARP CIC NOL6

8.65e-059839395162072f3afc95e46f29db3d79ebd930bc09726
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

SORBS1 PRDM16 PALLD

1.66e-041223931cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CBARP PALLD UNC5C

1.95e-04129393e7a15f98c3e6e4ee317e21958be3e413e3acd101
ToppCellPND28-Immune-Immune_Myeloid-DC-maDC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 BMP2K PALLD

3.22e-04153393b03375c54aa701817c0fc2c3fef32b870169e697
ToppCellPND28-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 BMP2K PALLD

3.22e-0415339318bd770a18e642581a6df144d47184c1ac383713
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ETV3 SORBS1 PALLD

3.41e-041563930f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ETV3 SORBS1 PALLD

3.41e-04156393cb87f12443fdc5538b856f765fcbac9406044e10
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SORBS1 NACAD UNC5C

3.47e-04157393432b8719a8afd289cf48068e12c26a349d753fcc
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

SORBS1 PALLD UNC5C

3.67e-04160393fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

SORBS1 PALLD UNC5C

3.74e-0416139364891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PALLD UNC5C

3.95e-04164393b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV3 BMP2K PALLD

3.95e-0416439378de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 GSX2 EGR1

4.02e-041653933f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D19 GATA3 NOL6

4.09e-04166393ceb0a48c0d853448fd45ac31dde046df9a178571
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSX2 RILP ACAN

4.09e-04166393a867dbcb36f7449062bd3d2293c67b67d14e2f99
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CBARP SORBS1 EGR1

4.16e-04167393c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EGR1 PRDM16 ACAN

4.38e-04170393a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K EGR1

4.61e-04173393869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K EGR1

4.61e-041733930672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SORBS1 PALLD UNC5C

4.61e-04173393a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K EGR1

4.61e-04173393870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SORBS1 PRDM16 UNC5C

4.77e-041753931125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RILP PRDM16 SSH3

4.77e-04175393c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR2 SORBS1 PRDM16

4.77e-04175393316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR2 SORBS1 PRDM16

4.77e-04175393a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

4.85e-041763939bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

4.85e-041763933f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 EGR1 ACAN

4.93e-0417739388403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 EGR1 ACAN

4.93e-041773938903aeaab61abd81a148ea623038c5114b8a183b
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

SORBS1 NACAD UNC5C

5.09e-041793931526a130565a97c291a25a7a988089bffc1515c1
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

SORBS1 PRDM16 UNC5C

5.09e-04179393a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.09e-04179393666072c0e8448dbaec1683d18368ec2502453f90
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SORBS1 PALLD UNC5C

5.18e-04180393d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

ETV3 BMP2K PALLD

5.26e-041813936252184ef098b911df50be4fe1b5565849a5b6b8
ToppCellRV|World / Chamber and Cluster_Paper

GBX1 SORBS1 PRDM16

5.26e-04181393bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EGR1 PALLD UNC5C

5.26e-041813936d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

ETV3 BMP2K PALLD

5.26e-04181393982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 EGR1 TOP2B

5.35e-041823931710eab3037a87609d21838be2d2d29c3bc36651
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 EGR1 PALLD

5.35e-04182393728a2152c166551ac229370c0900fe2bc426ea9b
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

5.35e-04182393eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 EGR1 TOP2B

5.35e-04182393e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.35e-041823935f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

SORBS1 PRDM16 UNC5C

5.43e-04183393818fd886e0188091310825f9145fa53328f2c979
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 CBARP EGR1

5.43e-04183393a0a3e4d07ac73dbbb1e019fd11e88ccffe6cf2ca
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

5.43e-04183393667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

5.43e-0418339328cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

5.43e-041833933fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.43e-041833932e831a4d99c6f983793df71c0994124c943c6da9
ToppCellPericytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

NACAD PALLD ACAN

5.52e-041843933d2d55d0f22874be21665ab37da710482f77fc36
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

5.52e-04184393e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 EGR1 TOP2B

5.52e-041843931154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 NACAD PALLD

5.52e-04184393590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 EGR1 TOP2B

5.61e-041853937adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 CBARP EGR1

5.69e-0418639311929e36d8c9b4c4bc2f5e912f139f474f91ab00
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

SORBS1 BMP2K PALLD

5.69e-04186393def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

SORBS1 PALLD UNC5C

5.78e-04187393464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.87e-04188393eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 ACAN UNC5C

5.87e-04188393b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PALLD ACAN UNC5C

5.87e-04188393116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.87e-04188393bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALLD ACAN UNC5C

5.97e-04189393fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 PRDM16 UNC5C

5.97e-041893937eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellASK452-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TBC1D19 GATA3 RUSC1-AS1

5.97e-04189393f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

SORBS1 PRDM16 PALLD

5.97e-041893935e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

SORBS1 PRDM16 PALLD

6.06e-04190393fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

BMPR2 EGR1 PALLD

6.15e-04191393ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

6.15e-0419139360c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

6.15e-04191393107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

GBX1 SORBS1 PALLD

6.15e-0419139325f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SORBS1 ACAN UNC5C

6.15e-04191393fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

B3GNT9 PALLD UNC5C

6.15e-04191393a05e9a7eb137d804570dd7d8905975d735738767
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

6.15e-04191393bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

6.15e-0419139309db184cb90fe282a14474d7217068c58092c6f8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GATA3 CBARP EGR1

6.15e-0419139365083daf317f66556dc047eb19297dcbe9c70299
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 BMP2K TOP2B

6.15e-04191393973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

SORBS1 PRDM16 ACAN

6.24e-041923939b06c7336624ef21f8e5393725b56038a8028e57
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EGR1 PALLD UNC5C

6.24e-041923932802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCellASK452-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SORBS1 BMP2K PALLD

6.24e-041923938269b88ff6073a908f547fcc7c5941f2e8289694
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 PALLD UNC5C

6.24e-0419239324e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 EGR1 PALLD

6.34e-041933934aa976b596830b585e8d9c808d5072ed23d13a7c
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

GATA3 FUZ BMPR2 SETD1B ACAN SSH3 SBNO2

1.70e-08179387331_DN
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A

TBC1D19 SMPD1 CLCN4 EGR1 NOL6

1.70e-051943852485_DN
DrugIopanoic acid [96-83-3]; Up 200; 7uM; HL60; HT_HG-U133A

CRTC1 SMPD1 CLCN4 BTBD7 MAN1B1

1.70e-051943852965_UP
DrugEpiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A

BMPR2 CLCN4 BMP2K SSH3 SBNO2

1.75e-051953852444_DN
DrugMinocycline hydrochloride [13614-98-7]; Down 200; 8uM; PC3; HT_HG-U133A

CRTC1 SMPD1 CLCN4 BMP2K SBNO2

1.75e-051953855077_DN
DrugBetonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A

CRTC1 CLCN4 EGR1 ACAN CIC

1.79e-051963853745_UP
DrugThioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; MCF7; HT_HG-U133A

CRTC1 BMP2K BTBD7 SSH3 SF3A1

1.79e-051963852236_DN
Drugphenformin hydrochloride; Up 200; 10uM; MCF7; HG-U133A

CLCN4 CIC SSH3 SBNO2 NOL6

1.83e-0519738521_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

FUZ SMPD1 EGR1 CIC SSH3

1.88e-051983853292_DN
DrugAmrinone [60719-84-8]; Down 200; 21.4uM; HL60; HT_HG-U133A

BMPR2 BMP2K EGR1 CIC SBNO2

1.88e-051983852724_DN
DrugCisapride [81098-60-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A

TBC1D19 BTBD7 CIC SSH3 SBNO2

1.88e-051983853305_DN
DrugThiocolchicoside [602-41-5]; Up 200; 7uM; PC3; HT_HG-U133A

ETV3 CRTC1 SORBS1 EGR1 ACAN

1.88e-051983855095_UP
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; HL60; HT_HG-U133A

TBC1D19 CLCN4 PALLD ACAN SSH3

1.88e-051983852206_UP
DrugArcaine sulfate [14923-17-2]; Up 200; 14.8uM; HL60; HT_HG-U133A

SMPD1 CBARP CLCN4 ACAN SSH3

1.88e-051983853010_UP
Drugalizarin red S

SCAP PALLD ACAN TOP2B

1.88e-0595384CID000008534
DrugBupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; HL60; HT_HG-U133A

BMP2K EGR1 SSH3 MAN1B1 SBNO2

1.93e-051993852404_DN
Drugexemestane; Up 200; 0.01uM; MCF7; HG-U133A

SMPD1 SETD1B EGR1 ACAN NOL6

1.93e-05199385165_UP
DrugZomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; HL60; HT_HG-U133A

SMPD1 BMP2K EGR1 SSH3 MAN1B1

1.93e-051993852713_DN
DrugAC1Q5ZRG

EGR1 CIC TOP2B

2.95e-0536383CID000004526
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

GATA3 SETD1B BTBD7 SBNO2

1.70e-041673843979_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

GATA3 SETD1B SSH3 SBNO2

1.90e-041723844112_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

GATA3 SETD1B SSH3 SBNO2

1.99e-041743845580_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

GATA3 SETD1B BTBD7 SBNO2

2.12e-041773843227_DN
DrugCamptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; PC3; HT_HG-U133A

SMPD1 CLCN4 EGR1 ACAN

2.21e-041793844541_UP
DrugMetergoline [17692-51-2]; Up 200; 10uM; MCF7; HT_HG-U133A

SORBS1 SETD1B EGR1 CIC

2.41e-041833843221_UP
Drug2-propylpentanoic acid; Down 200; 10000uM; MCF7; HG-U133A

GATA3 SETD1B ACAN SBNO2

2.67e-04188384345_DN
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A

SORBS1 EGR1 ACAN SBNO2

2.78e-041903845786_UP
DrugPrednisolone [50-24-8]; Up 200; 11uM; HL60; HT_HG-U133A

TBC1D19 CRTC1 PRDM16 PALLD

2.83e-041913842393_UP
DrugEtofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A

TBC1D19 EGR1 PRDM16 CIC

2.89e-041923844108_UP
DrugFlunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A

CLCN4 ACAN SSH3 SF3A1

2.89e-041923844303_UP
DrugEthynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A

TBC1D19 CRTC1 SETD1B SSH3

2.95e-041933845024_DN
DrugSulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A

BMPR2 EGR1 ACAN SSH3

2.95e-041933841817_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

BMPR2 BMP2K EGR1 PALLD

3.01e-041943844134_DN
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

SMPD1 BMPR2 BMP2K SBNO2

3.01e-041943843747_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A

CRTC1 EGR1 CIC SSH3

3.01e-041943843969_DN
DrugDipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A

CRTC1 EGR1 CIC SF3A1

3.01e-041943844310_UP
DrugAntazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; HL60; HG-U133A

SMPD1 ACAN SSH3 MAN1B1

3.01e-041943841556_UP
DrugGlipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A

SETD1B PRDM16 ACAN CIC

3.07e-041953844991_UP
Drugrapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A

GATA3 SMPD1 CBARP NOL6

3.07e-041953845980_DN
DrugClioquinol [130-26-7]; Down 200; 13uM; HL60; HT_HG-U133A

BMPR2 BTBD7 SSH3 MAN1B1

3.07e-041953843084_DN
DrugCAY10397; Up 200; 10uM; PC3; HT_HG-U133A

BMPR2 SETD1B BTBD7 SSH3

3.07e-041953847087_UP
DrugGuanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; PC3; HT_HG-U133A

GATA3 CRTC1 SORBS1 SSH3

3.07e-041953844660_DN
DrugGW8510; Up 200; 10uM; PC3; HT_HG-U133A

BMPR2 CLCN4 EGR1 SSH3

3.07e-041953847085_UP
DrugHexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; HL60; HT_HG-U133A

CRTC1 BMPR2 CLCN4 SSH3

3.07e-041953842708_DN
DrugCyanocobalamin [68-19-9]; Up 200; 3uM; MCF7; HT_HG-U133A

SETD1B PRDM16 CIC SSH3

3.13e-041963843252_UP
DrugBoldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TBC1D19 FUZ SMPD1 SBNO2

3.13e-041963844122_DN
DrugPiperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A

SMPD1 CLCN4 EGR1 BTBD7

3.13e-041963843763_UP
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SMPD1 BMP2K EGR1 BTBD7

3.13e-041963846263_DN
DrugEstropipate [7280-37-7]; Down 200; 9.2uM; PC3; HT_HG-U133A

CRTC1 SORBS1 BTBD7 SSH3

3.13e-041963844472_DN
DrugHarpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A

BMPR2 SSH3 MAN1B1 SBNO2

3.13e-041963842935_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A

CRTC1 BMP2K EGR1 SSH3

3.13e-041963841864_DN
DrugDemeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A

SMPD1 SORBS1 EGR1 PRDM16

3.13e-041963843604_UP
DrugMethoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A

CRTC1 SMPD1 BMP2K SBNO2

3.13e-041963845007_DN
Drugvalinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A

GATA3 CRTC1 ACAN SSH3

3.13e-041963845962_DN
DrugEdrophonium chloride [116-38-1]; Up 200; 19.8uM; HL60; HG-U133A

BTBD7 ACAN MAN1B1 NOL6

3.13e-041963842019_UP
DrugEnoxacin [74011-58-8]; Down 200; 12.4uM; PC3; HT_HG-U133A

FUZ CRTC1 SORBS1 CLCN4

3.13e-041963844655_DN
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A

CRTC1 CLCN4 EGR1 ACAN

3.13e-041963843729_UP
DrugMifepristone [84371-65-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

CIC SSH3 SF3A1 NOL6

3.13e-041963847183_DN
DrugEthotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A

CRTC1 BMP2K BTBD7 SSH3

3.13e-041963844366_DN
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; HL60; HT_HG-U133A

CLCN4 EGR1 SBNO2 NOL6

3.13e-041963843118_DN
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

SETD1B BMP2K ACAN SSH3

3.13e-041963846673_DN
DrugProcarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A

BMP2K BTBD7 MAN1B1 SBNO2

3.13e-041963843533_DN
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; HL60; HT_HG-U133A

BMPR2 CLCN4 CIC SSH3

3.19e-041973842141_DN
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A

SMPD1 BMP2K SSH3 SBNO2

3.19e-041973842554_DN
DrugNorcyclobenzaprine [303-50-4]; Down 200; 15.4uM; PC3; HT_HG-U133A

GATA3 CRTC1 CLCN4 BMP2K

3.19e-041973844190_DN
DrugPiromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A

CRTC1 BMP2K BTBD7 SBNO2

3.19e-041973844575_DN
Drugrapamycin; Down 200; 0.1uM; MCF7; HG-U133A

CLCN4 PALLD MAN1B1 NOL6

3.19e-04197384326_DN
DrugLorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; PC3; HT_HG-U133A

GATA3 FUZ SORBS1 CLCN4

3.19e-041973844658_DN
DrugChlorpropamide [94-20-2]; Down 200; 14.4uM; PC3; HT_HG-U133A

SCAP BMP2K SF3A1 MAN1B1

3.19e-041973846291_DN
DrugRamipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A

FUZ BMP2K BTBD7 SBNO2

3.19e-041973843572_DN
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A

TBC1D19 CLCN4 BMP2K BTBD7

3.19e-041973845939_UP
DrugTrimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A

CRTC1 BMP2K BTBD7 CIC

3.19e-041973842307_DN
DrugClebopride maleate [84370-95-6]; Up 200; 8.2uM; PC3; HT_HG-U133A

TBC1D19 SETD1B BTBD7 SBNO2

3.19e-041973846311_UP
DrugAlclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; HL60; HT_HG-U133A

FUZ BMP2K SSH3 SBNO2

3.19e-041973842532_DN
DrugColistin sulfate [1264-72-8]; Down 200; 3uM; HL60; HT_HG-U133A

FUZ EGR1 BTBD7 SSH3

3.19e-041973842491_DN
DrugBendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

FUZ SMPD1 SCAP SSH3

3.19e-041973843415_DN
DrugUngerine nitrate; Down 200; 10.2uM; HL60; HT_HG-U133A

BMP2K EGR1 BTBD7 SBNO2

3.19e-041973842514_DN
DrugBenfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A

CRTC1 CLCN4 EGR1 PRDM16

3.19e-041973842177_UP
DrugArcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

TBC1D19 EGR1 BTBD7 SSH3

3.19e-041973844974_DN
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A

FUZ SMPD1 SF3A1 SBNO2

3.19e-041973846663_DN
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A

CRTC1 CIC SSH3 SBNO2

3.19e-041973843877_DN
DrugArecoline hydrobromide [300-08-3]; Up 200; 17uM; HL60; HT_HG-U133A

BMP2K EGR1 SBNO2 NOL6

3.19e-041973841303_UP
DrugMinaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

SMPD1 BTBD7 CIC SSH3

3.19e-041973841468_DN
DrugChlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A

CRTC1 BMP2K EGR1 BTBD7

3.19e-041973841541_DN
DrugMephenytoin [50-12-4]; Down 200; 18.4uM; PC3; HT_HG-U133A

FUZ SMPD1 EGR1 BTBD7

3.19e-041973845801_DN
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A

GATA3 CRTC1 SSH3 SBNO2

3.19e-041973845735_DN
DrugLY294002; Down 200; 10uM; SKMEL5; HG-U133A

CRTC1 SORBS1 ACAN NOL6

3.25e-04198384501_DN
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; HL60; HT_HG-U133A

SMPD1 CLCN4 EGR1 BTBD7

3.25e-041983841291_DN
Drugnocodazole; Down 200; 1uM; MCF7; HG-U133A

FUZ BMPR2 CIC NOL6

3.25e-04198384621_DN
DrugNitrendipine [39562-70-4]; Down 200; 11uM; PC3; HT_HG-U133A

GATA3 FUZ BMP2K MAN1B1

3.25e-041983846304_DN
DrugTiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A

CLCN4 PALLD SSH3 SBNO2

3.25e-041983842492_UP
DrugDoxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A

ZNF106 SORBS1 BTBD7 SSH3

3.25e-041983843479_UP
DrugFlutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A

GATA3 EGR1 SSH3 MAN1B1

3.25e-041983842358_UP
DrugOxyphenbutazone [129-20-4]; Up 200; 12.4uM; HL60; HT_HG-U133A

TBC1D19 CRTC1 PALLD ACAN

3.25e-041983846160_UP
DrugBiotin [58-85-5]; Down 200; 16.4uM; HL60; HT_HG-U133A

FUZ CLCN4 BMP2K SBNO2

3.25e-041983842428_DN
DrugBromopride [4093-35-0]; Down 200; 11.6uM; HL60; HT_HG-U133A

BMPR2 EGR1 SSH3 SBNO2

3.25e-041983842182_DN
DrugEquilin [474-86-2]; Down 200; 15uM; PC3; HT_HG-U133A

FUZ CRTC1 SORBS1 CLCN4

3.25e-041983844659_DN
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

TBC1D19 EGR1 BTBD7 SSH3

3.25e-041983845793_DN
DrugAzapropazone [13539-59-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A

FUZ CRTC1 SORBS1 CLCN4

3.25e-041983846522_UP
DrugMetronidazole [443-48-1]; Up 200; 23.4uM; PC3; HG-U133A

CLCN4 BMP2K EGR1 ACAN

3.25e-041983841921_UP
Diseasecardiovascular disease

TBC1D19 CRTC1 SORBS1 PRDM16 UNC5C

2.53e-04457375EFO_0000319
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

GATA3 CRTC1

2.58e-0419372EFO_0000220, GO_0097327
Diseaseasthma (is_marker_for)

GATA3 BMPR2 EGR1

5.31e-04126373DOID:2841 (is_marker_for)
DiseaseFEV/FEC ratio

GSX2 ZNF106 CRTC1 CLCN4 PRDM16 ACAN TOP2B

7.31e-041228377EFO_0004713
DiseaseRheumatoid Arthritis

GATA3 B3GNT9 ACAN

1.35e-03174373C0003873
Diseaseadipose tissue measurement

SORBS1 PRDM16

1.46e-0345372EFO_0004764
Diseaseoptic disc size measurement

GSX2 PRDM16 UNC5C

2.16e-03205373EFO_0004832
Diseasepulmonary hypertension (is_marker_for)

BMPR2 EGR1

2.94e-0364372DOID:6432 (is_marker_for)
Diseasekeratoconus

ZNF106 CRTC1

3.12e-0366372MONDO_0015486
Diseasepulmonary hypertension (biomarker_via_orthology)

BMPR2 EGR1

4.55e-0380372DOID:6432 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
AVAFPHPRPFLASPP

CBARP

366

Q8N350
AVSPVFFQLPAPHPP

LINC01590

6

Q5TEZ4
HESTPVNSFPPPFIE

SMPD1

321

P17405
PPVPTASSRFHFPPL

ETV3

141

P41162
FTEEPPELPANSPHP

CLCN4

676

P51793
NHPPEDPFGSVPFIS

BMP2K

671

Q9NSY1
FAPSPTLPPTFHPEE

RC3H1

776

Q5TC82
FPSHLFLEQRSPPPP

RBM33

471

Q96EV2
DHPPPPESKIQSFFG

RILP

331

Q96NA2
APTFPTPNTDIFPEP

EGR1

206

P18146
SLPEPHPGPDFFIPL

GSX2

21

Q9BZM3
HPEPFTPPSSPQVGF

NOL6

886

Q9H6R4
SELPFPSHVLPEPGF

PHRF1

1451

Q9P1Y6
PSHVLPEPGFPDTDP

PHRF1

1456

Q9P1Y6
PPPPPHRDFISVTLS

MAN1B1

41

Q9UKM7
PSEEPFPSVRPFPSV

ACAN

801

P16112
PFPSVELFPSEEPFP

ACAN

811

P16112
HFPPPPPILETSSLE

PALLD

561

Q8WX93
ASPHLFTFPPTPPKD

GATA3

146

P23771
PPPPHFSETFPSLPA

GBX1

166

Q14549
NIHFPSPLPTPLDPE

CRTC1

251

Q6UUV9
FPPPDTTPLSPPHSF

BMPR2

131

Q13873
TDLDSFVAFHPPLPP

BTBD7

746

Q9P203
SHPDPAFSIFPPDAP

SCAP

571

Q12770
LVTSTHFPPEPGPPE

FUZ

336

Q9BT04
EEPLHLFFAPPSPPN

RFPL1

276

O75677
FPSDFPTEPPSLPRT

TOP2B

1586

Q02880
IPVGPPSPFPTSEDF

PRDM16

46

Q9HAZ2
EAFPPPPHFSFPAPL

SBNO2

1266

Q9Y2G9
HFPPPPEEPTATAAF

SETD1B

406

Q9UPS6
SSDPPPAFSVFCHPP

RUSC1-AS1

216

Q66K80
PPPEFEFIADPPSIS

SF3A1

146

Q15459
EEHPAPEVSTPFPPL

SSH3

486

Q8TE77
DTPAPPTPTGPFDFA

B3GNT9

71

Q6UX72
SSFTHCRPPLDPEPP

CIC

501

Q96RK0
DPEIAAETPPPPHAS

CNK3/IPCEF1

621

G9CGD6
VGLLPTPPEHFPFSD

ZC3H6

396

P61129
PLTFPTLDDFIPPHL

SORBS1

201

Q9BX66
LSVFPLPSHPAAPPE

TBC1D19

71

Q8N5T2
ETFPSDPPEPLPHFL

UNC5C

51

O95185
FPLFLEPPSSHVSPS

ZNF106

1156

Q9H2Y7
LSVPSPPPDPDSFFT

NACAD

161

O15069