Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	FLNA FLNB FLNC MYO5A MYO6 CD2AP TRIOBP MYO5C GAS2L2 MYO18B	4.68e-06	227	140	10	GO:0051015
GeneOntologyMolecularFunction	actin binding	EPS8 FLNA FLNB FLNC MYO5A MYO6 CD2AP TRIOBP GBP3 SHANK3 MYO5C GAS2L2 MYO18B ALDOA	7.14e-06	479	140	14	GO:0003779
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	HS3ST5 HS3ST6 HS3ST2	1.16e-05	7	140	3	GO:0008467
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	HS3ST5 HS3ST6 HS3ST2	1.44e-04	15	140	3	GO:0034483
GeneOntologyMolecularFunction	2'-5'-oligoadenylate synthetase activity	OAS2 OAS3	4.81e-04	5	140	2	GO:0001730
GeneOntologyMolecularFunction	sulfotransferase activity	TPST2 HS3ST5 HS3ST6 HS3ST2	5.98e-04	55	140	4	GO:0008146
GeneOntologyMolecularFunction	cytoskeletal protein binding	EPS8 FLNA FLNB FLNC MYO5A GAPDH MYO6 CD2AP TRIOBP GBP3 MAST2 SHANK3 MYO5C EML5 GAS2L2 CCSER2 MYO18B ALDOA	6.84e-04	1099	140	18	GO:0008092
GeneOntologyMolecularFunction	fructose binding	SLC2A5 ALDOA	7.19e-04	6	140	2	GO:0070061
GeneOntologyCellularComponent	actin cytoskeleton	FLNA FLNB FLNC MYO5A MYO6 CD2AP TRIOBP GBP3 MYO5C GAS2L2 AHNAK MYO18B ALDOA ARHGAP21	2.85e-05	576	138	14	GO:0015629
GeneOntologyCellularComponent	unconventional myosin complex	MYO5A MYO6 MYO18B	4.47e-05	11	138	3	GO:0016461
GeneOntologyCellularComponent	actin filament	FLNA MYO5A MYO6 CD2AP GAS2L2 MYO18B	4.22e-04	146	138	6	GO:0005884
GeneOntologyCellularComponent	brush border	EPS8 FLNA FLNB TMPRSS15 MYO6 PDZK1	5.23e-04	152	138	6	GO:0005903
GeneOntologyCellularComponent	myosin complex	MYO5A MYO6 MYO5C MYO18B	6.25e-04	59	138	4	GO:0016459
GeneOntologyCellularComponent	cluster of actin-based cell projections	EPS8 FLNA FLNB TMPRSS15 MYO6 PDZK1 TRIOBP	7.12e-04	223	138	7	GO:0098862
MousePheno	decreased fetal size	FLNC POLR2A POGZ OLA1 SUCLA2 ALKBH1 SAFB CSF2 NIPBL NOVA1	1.09e-05	229	108	10	MP:0004200
MousePheno	abnormal fetal size	FLNC POLR2A POGZ OLA1 SUCLA2 ALKBH1 SAFB CSF2 NIPBL NOVA1	1.47e-05	237	108	10	MP:0004198
Domain	P-loop_NTPase	TPST2 THNSL1 MYO5A MYO6 HS3ST5 GBP3 ABCC9 RECQL MSH5 OLA1 CLPX CMSS1 RUVBL2 ABCA9 MYO5C AK5 YLPM1 HS3ST6 MYO18B HS3ST2 ATP5F1A	1.09e-06	848	138	21	IPR027417
Domain	MAM	TMPRSS15 NRP2 MEP1A PTPRM	6.30e-06	17	138	4	SM00137
Domain	MAM	TMPRSS15 NRP2 MEP1A PTPRM	8.06e-06	18	138	4	PF00629
Domain	MAM_dom	TMPRSS15 NRP2 MEP1A PTPRM	8.06e-06	18	138	4	IPR000998
Domain	MAM_2	TMPRSS15 NRP2 MEP1A PTPRM	8.06e-06	18	138	4	PS50060
Domain	-	TPST2 THNSL1 HS3ST5 GBP3 ABCC9 RECQL MSH5 OLA1 CLPX CMSS1 RUVBL2 ABCA9 AK5 YLPM1 HS3ST6 HS3ST2 ATP5F1A	3.66e-05	746	138	17	3.40.50.300
Domain	IG_FLMN	FLNA FLNB FLNC	4.56e-05	10	138	3	SM00557
Domain	Filamin	FLNA FLNB FLNC	6.24e-05	11	138	3	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB FLNC	6.24e-05	11	138	3	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB FLNC	6.24e-05	11	138	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB FLNC	6.24e-05	11	138	3	IPR017868
Domain	PDZ	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	8.56e-05	141	138	7	PF00595
Domain	PDZ	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	1.16e-04	148	138	7	SM00228
Domain	-	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	1.26e-04	150	138	7	2.30.42.10
Domain	PDZ	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	1.31e-04	151	138	7	PS50106
Domain	PDZ	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	1.37e-04	152	138	7	IPR001478
Domain	Sulfotransfer_1	TPST2 HS3ST5 HS3ST6 HS3ST2	1.40e-04	36	138	4	PF00685
Domain	Sulfotransferase_dom	TPST2 HS3ST5 HS3ST6 HS3ST2	1.40e-04	36	138	4	IPR000863
Domain	ATP-grasp_succ-CoA_synth-type	ACLY SUCLA2	1.62e-04	3	138	2	IPR013650
Domain	Succ-CoA_synthase_bsu_CS	ACLY SUCLA2	1.62e-04	3	138	2	IPR017866
Domain	ATP-grasp_2	ACLY SUCLA2	1.62e-04	3	138	2	PF08442
Domain	SPOC_met	RBM15 RBM15B	1.62e-04	3	138	2	IPR010912
Domain	SUCCINYL_COA_LIG_3	ACLY SUCLA2	1.62e-04	3	138	2	PS01217
Domain	Myosin_head_motor_dom	MYO5A MYO6 MYO5C MYO18B	1.73e-04	38	138	4	IPR001609
Domain	MYOSIN_MOTOR	MYO5A MYO6 MYO5C MYO18B	1.73e-04	38	138	4	PS51456
Domain	Myosin_head	MYO5A MYO6 MYO5C MYO18B	1.73e-04	38	138	4	PF00063
Domain	MYSc	MYO5A MYO6 MYO5C MYO18B	1.73e-04	38	138	4	SM00242
Domain	IQ	MYO5A MYO6 MYO5C CEP131 MYO18B	1.80e-04	71	138	5	PF00612
Domain	MAM_1	TMPRSS15 MEP1A PTPRM	2.06e-04	16	138	3	PS00740
Domain	-	ACLY CPS1 SUCLA2	2.97e-04	18	138	3	3.30.470.20
Domain	CoA_ligase	ACLY SUCLA2	3.22e-04	4	138	2	IPR005811
Domain	OAS1_C	OAS2 OAS3	3.22e-04	4	138	2	PF10421
Domain	2-5-oligoadenylate_synth_CS	OAS2 OAS3	3.22e-04	4	138	2	IPR006117
Domain	25A_SYNTH_3	OAS2 OAS3	3.22e-04	4	138	2	PS50152
Domain	Succinyl-CoA_synth-like	ACLY SUCLA2	3.22e-04	4	138	2	IPR016102
Domain	2-5-oligoAdlate_synth_1_dom2/C	OAS2 OAS3	3.22e-04	4	138	2	IPR018952
Domain	2-5A_synthase	OAS2 OAS3	3.22e-04	4	138	2	IPR026774
Domain	SPOC	RBM15 RBM15B	3.22e-04	4	138	2	PS50917
Domain	-	OAS2 OAS3	3.22e-04	4	138	2	1.10.1410.20
Domain	25A_SYNTH_1	OAS2 OAS3	3.22e-04	4	138	2	PS00832
Domain	25A_SYNTH_2	OAS2 OAS3	3.22e-04	4	138	2	PS00833
Domain	Ligase_CoA	ACLY SUCLA2	3.22e-04	4	138	2	PF00549
Domain	-	ACLY SUCLA2	3.22e-04	4	138	2	3.40.50.261
Domain	IQ	MYO5A MYO6 MYO5C CEP131 MYO18B	3.34e-04	81	138	5	SM00015
Domain	CUB	TMPRSS15 CSMD2 ADGRG6 NRP2	4.67e-04	49	138	4	PF00431
Domain	CUB	TMPRSS15 CSMD2 ADGRG6 NRP2	5.05e-04	50	138	4	SM00042
Domain	-	RBM15 RBM15B	5.34e-04	5	138	2	2.40.290.10
Domain	2-5-oligoadenylate_synth_N	OAS2 OAS3	5.34e-04	5	138	2	IPR006116
Domain	Myosin_S1_N	MYO5A MYO5C	5.34e-04	5	138	2	IPR008989
Domain	SPOC-like_C_dom	RBM15 RBM15B	5.34e-04	5	138	2	IPR016194
Domain	IQ_motif_EF-hand-BS	MYO5A MYO6 MYO5C CEP131 MYO18B	5.44e-04	90	138	5	IPR000048
Domain	-	TMPRSS15 CSMD2 ADGRG6 NRP2	5.87e-04	52	138	4	2.60.120.290
Domain	ACTININ_2	FLNA FLNB FLNC	6.27e-04	23	138	3	PS00020
Domain	ACTININ_1	FLNA FLNB FLNC	6.27e-04	23	138	3	PS00019
Domain	Actinin_actin-bd_CS	FLNA FLNB FLNC	6.27e-04	23	138	3	IPR001589
Domain	CUB	TMPRSS15 CSMD2 ADGRG6 NRP2	6.31e-04	53	138	4	PS01180
Domain	IQ	MYO5A MYO6 MYO5C CEP131 MYO18B	6.32e-04	93	138	5	PS50096
Domain	Dilute_dom	MYO5A MYO5C	7.97e-04	6	138	2	IPR002710
Domain	SPOC_C	RBM15 RBM15B	7.97e-04	6	138	2	IPR012921
Domain	DIL	MYO5A MYO5C	7.97e-04	6	138	2	PF01843
Domain	DILUTE	MYO5A MYO5C	7.97e-04	6	138	2	PS51126
Domain	DIL	MYO5A MYO5C	7.97e-04	6	138	2	SM01132
Domain	SPOC	RBM15 RBM15B	7.97e-04	6	138	2	PF07744
Domain	CUB_dom	TMPRSS15 CSMD2 ADGRG6 NRP2	8.32e-04	57	138	4	IPR000859
Domain	CH	FLNA FLNB FLNC GAS2L2	1.36e-03	65	138	4	SM00033
Domain	ATP_grasp_subdomain_2	ACLY CPS1 SUCLA2	1.52e-03	31	138	3	IPR013816
Domain	CH	FLNA FLNB FLNC GAS2L2	1.79e-03	70	138	4	PF00307
Domain	-	FLNA FLNB FLNC GAS2L2	1.89e-03	71	138	4	1.10.418.10
Domain	CH	FLNA FLNB FLNC GAS2L2	2.09e-03	73	138	4	PS50021
Domain	CH-domain	FLNA FLNB FLNC GAS2L2	2.31e-03	75	138	4	IPR001715
Domain	NTP_transf_2	OAS2 OAS3	2.85e-03	11	138	2	PF01909
Domain	Polymerase_NTP_transf_dom	OAS2 OAS3	2.85e-03	11	138	2	IPR002934
Domain	ATP_GRASP	CPS1 SUCLA2	4.65e-03	14	138	2	PS50975
Domain	ATP-grasp	CPS1 SUCLA2	4.65e-03	14	138	2	IPR011761
Domain	-	CPS1 SUCLA2	5.34e-03	15	138	2	3.30.1490.20
Domain	ConA-like_dom	TMPRSS15 COL15A1 ADGRG6 NRP2 MEP1A PTPRM	5.79e-03	219	138	6	IPR013320
Domain	Post-SET_dom	ASH1L KMT2C	6.08e-03	16	138	2	IPR003616
Domain	PostSET	ASH1L KMT2C	6.08e-03	16	138	2	SM00508
Domain	POST_SET	ASH1L KMT2C	6.08e-03	16	138	2	PS50868
Pathway	REACTOME_OAS_ANTIVIRAL_RESPONSE	FLNA OAS2 OAS3	3.08e-05	9	103	3	M27859
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNA FLNB FLNC	5.99e-05	11	103	3	M48099
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNA FLNB FLNC RBM15 MYO5A TCOF1 GAPDH ACLY POLR2A OLA1 RUVBL2 MYO5C SAFB GANAB RPAP1 SUGP2 AHNAK TBK1 MDC1 YLPM1 SAFB2 CEP131 NOP2 NIPBL ATP5F1A	6.59e-13	1024	142	25	24711643
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLNA RBM15 PTTG1 TCOF1 ACLY POLR2A USP24 ZNF507 POGZ POLR1G GPRIN1 EMSY SAFB RPAP1 SUGP2 MDC1 YLPM1 TPX2 RBM15B SAFB2 NOP2 NIPBL	9.57e-13	774	142	22	15302935
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	FLNA TCOF1 GAPDH ACLY POLR2A CD2AP USP24 MPDZ POGZ GPRIN1 RUVBL2 EMSY KMT2C YEATS4 SUGP2 AHNAK MDC1 YLPM1 TPX2	1.30e-12	549	142	19	38280479
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA FLNB FLNC RBM15 MYO5A GAPDH MYO6 ACLY POLR2A OAS3 RECQL POGZ CLPX CMSS1 POLR1G RUVBL2 ALKBH1 SAFB NOP14 SUGP2 AHNAK MDC1 SAFB2 ALDOA NOP2 NIPBL ATP5F1A	7.56e-12	1353	142	27	29467282
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	FLNA FLNB FLNC MYO5A ITIH2 GANAB AHNAK ATP5F1A	1.45e-11	46	142	8	33403043
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	FLNA FLNB FLNC RBM15 TCOF1 GAPDH ACLY POLR2A RECQL CMSS1 POLR1G RUVBL2 SAFB NOP14 SUGP2 AHNAK MDC1 FDXR YLPM1 TPX2 SAFB2 NOP2 ATP5F1A	1.62e-11	989	142	23	36424410
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA FLNB FLNC RBM15 MYO5A TCOF1 ACLY POLR2A USP24 RECQL POGZ GANAB NOP14 SUGP2 AHNAK MDC1 YLPM1 NOP2 NIPBL	2.60e-11	653	142	19	22586326
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNA FLNB FLNC RBM15 TCOF1 GAPDH ACLY CD2AP TRIOBP EMSY SAFB GANAB SNCAIP AHNAK NIPBL	2.62e-11	360	142	15	33111431
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	EPS8 FLNA FLNB COL15A1 GAPDH MYO6 ACLY PDZK1 CD2AP OLA1 GFUS SUCLA2 SLC2A5 GANAB EML5 AHNAK NID1 ALDOA BBOX1 CPVL NIPBL ATP5F1A GOT1	2.77e-11	1016	142	23	19056867
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	FLNA FLNB RBM15 MYO5A TCOF1 GAPDH MYO6 ACLY CPS1 CMSS1 POLR1G MYO5C SAFB GANAB AHNAK TBK1 MDC1 TPX2 SAFB2 ALDOA NOP2 ATP5F1A	4.98e-11	949	142	22	36574265
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNA FLNB RBM15 TCOF1 GAPDH MYO6 ACLY POLR2A RECQL POGZ OLA1 CLPX SUCLA2 MAST2 RUVBL2 SAFB GANAB TBK1 MDC1 RBM15B SAFB2 MYO18B ALDOA NOP2 NIPBL ATP5F1A	1.37e-10	1425	142	26	30948266
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	FLNA FLNB RBM15 TCOF1 GAPDH POLR2A POGZ RUVBL2 SAFB GANAB AHNAK MDC1 TPX2 SAFB2 ALDOA NOP2 NIPBL ATP5F1A	2.09e-10	652	142	18	31180492
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB FLNC CD4	1.33e-09	5	142	4	19366992
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FLNA FLNB RBM15 MYO5A GAPDH MYO6 ACLY OAS3 RECQL CMSS1 KRT79 RUVBL2 ITIH2 SAFB NOP14 AHNAK MDC1 TPX2 RBM15B SAFB2 ALDOA NOP2 ATP5F1A	1.73e-09	1257	142	23	36526897
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	FLNA RBM15 TCOF1 GAPDH MYO6 ACLY OAS3 POGZ OLA1 CLPX CMSS1 SUCLA2 RUVBL2 ITIH2 SUGP2 AHNAK TBK1 YLPM1 TPX2 RBM15B CEP131 ALDOA NOP2 ATP5F1A	1.75e-09	1371	142	24	36244648
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	FLNA RBM15 GAPDH POLR2A CD2AP POGZ RFX5 EMSY SAFB SUGP2 AHNAK MDC1 YLPM1 TPX2 RBM15B SAFB2 ALDOA NOP2 NIPBL ATP5F1A	2.29e-09	954	142	20	36373674
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	EPS8 FLNA FLNB CLTCL1 COL15A1 MYO5A GAPDH ACLY CD2AP KRT79 ITIH2 SLC2A5 MYO5C GANAB CLN5 NID1 PABPC1L ALDOA CPVL ATP5F1A GOT1	2.81e-09	1070	142	21	23533145
Pubmed	Human transcription factor protein interaction networks.	MYO5A MYO6 ZNF507 MECOM POGZ CLPX RUVBL2 RFX5 EMSY MYO5C KMT2C YEATS4 GANAB NOP14 SUGP2 MDC1 YLPM1 TPX2 PABPC1L CEP131 TAL1 NOP2 CPVL NIPBL	3.91e-09	1429	142	24	35140242
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	FLNA RBM15 GAPDH ACLY ZNF507 RECQL POGZ OLA1 CMSS1 RUVBL2 RFX5 EMSY KMT2C SAFB NOP14 SUGP2 TPX2 SAFB2 ALDOA NOP2 NIPBL	4.77e-09	1103	142	21	34189442
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	FLNA TCOF1 GAPDH MYO6 ACLY POLR2A GPRIN1 EMSY SAFB SUGP2 AHNAK YLPM1 TPX2 SAFB2 ALDOA NOP2 NIPBL ARHGAP21 ATP5F1A	9.67e-09	934	142	19	33916271
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	FLNA FLNB MYO5A GAPDH MYO6 ACLY RUVBL2 MYO5C AHNAK ALDOA ATP5F1A	1.52e-08	268	142	11	33024031
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TICRR RBM15 TCOF1 POLR2A MECOM POGZ POLR1G RUVBL2 RFX5 EMSY KMT2C SAFB YEATS4 AHNAK MDC1 YLPM1 TPX2 RBM15B SAFB2 NOP2 NIPBL ATP5F1A	1.52e-08	1294	142	22	30804502
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	FLNA FLNB RBM15 MYO5A TCOF1 POLR2A CMSS1 SAFB NOP14 SUGP2 YLPM1 RBM15B SAFB2 ALDOA NOP2 NOVA1 NOVA2	3.74e-08	807	142	17	22681889
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNA FLNB FLNC CLTCL1 GAPDH ACLY POLR2A ASH1L GBP3 OLA1 KRT79 RUVBL2 SAFB GANAB AHNAK ALDOA ATP5F1A	3.74e-08	807	142	17	30575818
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNA FLNB RBM15 MYO5A ACLY MAST2 AHNAK MDC1 TPX2 NOP2	4.80e-08	234	142	10	36243803
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM15 MYO5A TCOF1 GAPDH CMSS1 POLR1G RUVBL2 SAFB NOP14 SUGP2 RBM15B SAFB2 ALDOA NOP2 ATP5F1A NOVA2	5.75e-08	731	142	16	29298432
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB FLNC	6.66e-08	3	142	3	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB FLNC	6.66e-08	3	142	3	11153914
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB FLNC	6.66e-08	3	142	3	11252955
Pubmed	RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.	RBM15 TCOF1 MYO6 RECQL POGZ RUVBL2 SAFB NOP2 ATP5F1A	6.95e-08	183	142	9	28186131
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	FLNA FLNB FLNC RBM15 GAPDH MYO6 ACLY GANAB SUGP2 AHNAK ALDOA NOP2 ATP5F1A	9.03e-08	477	142	13	31300519
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	EPS8 FLNA FLNB RBM15 MYO5A MYO6 ACLY RECQL RUVBL2 SAFB AHNAK MDC1 YLPM1 SAFB2 NOP2	9.45e-08	660	142	15	32780723
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	FLNA RBM15 TMPRSS15 TCOF1 GAPDH ACLY USP24 RECQL CLPX POLR1G SUCLA2 RUVBL2 EMSY SAFB GANAB NOP14 AHNAK SAFB2 NOP2 NIPBL ATP5F1A	9.97e-08	1318	142	21	30463901
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNA FLNB FLNC GAPDH MYO6 ACLY AHNAK ALDOA ATP5F1A	1.00e-07	191	142	9	33762435
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNA FLNB FLNC USP13 RBM15 THNSL1 TCOF1 MYO6 MPDZ CLPX CMSS1 USP37 SUCLA2 KRT79 SAFB TBK1 YLPM1 ALDOA	1.64e-07	1005	142	18	19615732
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	EPS8 FLNA FLNB TCOF1 GAPDH MYO6 RUVBL2 YEATS4 MDC1 YLPM1 TPX2 NOP2 ATP5F1A	1.78e-07	506	142	13	30890647
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	FLNA FLNB FLNC TCOF1 GAPDH CD2AP OAS3 RECQL OLA1 CLPX GFUS GPRIN1 SUCLA2 RUVBL2 EMSY SAFB AHNAK YLPM1 ALDOA NOP2 ATP5F1A	1.83e-07	1367	142	21	32687490
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	FLNA FLNC TCOF1 GAPDH ACLY CD2AP OLA1 RUVBL2 GANAB AHNAK TBK1 YLPM1 ALDOA NOP2 ARHGAP21 ATP5F1A	2.26e-07	809	142	16	32129710
Pubmed	Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.	FLNA FLNB ACLY GANAB AHNAK RBM15B ALDOA ATP5F1A	2.26e-07	152	142	8	16009940
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB TCOF1 GAPDH MYO6 ACLY CD2AP USP24 MPDZ GPRIN1 RUVBL2 GRIP1 GANAB AHNAK ARHGAP21 ATP5F1A	2.32e-07	708	142	15	39231216
Pubmed	A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.	FLNA FLNB FLNC CLTCL1 GAPDH RUVBL2 ALDOA ATP5F1A	2.38e-07	153	142	8	27462432
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB FLNC	2.66e-07	4	142	3	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB FLNC	2.66e-07	4	142	3	22802962
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNA FLNC MYO5A MYO6 ACLY CD2AP TRIOBP RECQL POGZ OLA1 RUVBL2 SUGP2 AHNAK YLPM1 NOP2	3.08e-07	724	142	15	36232890
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	FLNA FLNB TCOF1 GAPDH ACLY POLR2A USP24 RECQL OLA1 CPS1 CLPX CMSS1 KRT79 RUVBL2 GANAB AHNAK MDC1 ALDOA NOP2 NIPBL ATP5F1A	3.22e-07	1415	142	21	28515276
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TICRR FLNB GAPDH TOPAZ1 ACLY POLR2A CSMD2 GPRIN1 KMT2C FRY RPAP1 GALNT11 SYDE2 AHNAK TBK1	3.79e-07	736	142	15	29676528
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	FLNB RBM15 POLR2A CD2AP MECOM RECQL RFX5 YEATS4 AHNAK TBK1 TPX2 CEP131 NOP2 CPVL	4.49e-07	645	142	14	25281560
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FLNC ZCWPW1 ACLY POLR2A MECOM RECQL POGZ CPS1 CMSS1 EMSY YEATS4 NOP14 SUGP2 TPX2 NOVA1 NOVA2	4.86e-07	857	142	16	25609649
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	FLNA RBM15 ACLY POLR2A OLA1 CLPX SAFB GANAB NOP14 YLPM1 TPX2 SAFB2 ALDOA NOP2	5.20e-07	653	142	14	33742100
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB FLNC	6.62e-07	5	142	3	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB FLNC	6.62e-07	5	142	3	17360453
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	FLNA FLNC MYO5A GAPDH MYO6 ACLY CLPX AHNAK ALDOA ATP5F1A	6.84e-07	312	142	10	37120454
Pubmed	Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.	TCOF1 CD2AP POLR1G ITIH2 GPR179 SAFB AHNAK ALDOA ATP5F1A	7.63e-07	243	142	9	36964488
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	FLNA FLNB CLTCL1 TCOF1 GAPDH MYO6 RUVBL2 AHNAK NOP2	8.17e-07	245	142	9	21182205
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	FLNA FLNB FLNC TCOF1 GAPDH ACLY RUVBL2 GANAB AHNAK TPX2 ALDOA NOP2	9.69e-07	494	142	12	26831064
Pubmed	Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.	FLNA MYO6 ACLY ATP5F1A	9.84e-07	19	142	4	32888949
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	FLNA FLNB ACLY POLR2A USP24 OLA1 GPRIN1 RUVBL2 GRIP1 SUGP2 AHNAK ARHGAP21	1.05e-06	498	142	12	36634849
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNA FLNB FLNC MYO5A TCOF1 GAPDH MYO6 ACLY CD2AP MPDZ RECQL RUVBL2 GANAB AHNAK ALDOA CPVL ATP5F1A GOT1	1.13e-06	1149	142	18	35446349
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLNA FLNB RBM15 PTTG1 TCOF1 USP24 POLR1G SAFB TPX2 CEP131 NOP2 NIPBL	1.17e-06	503	142	12	16964243
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	FLNA POLR2A MECOM OAS3 POGZ SUCLA2 RUVBL2 GANAB SUGP2 AHNAK TBK1 SBF2 ATP5F1A	1.23e-06	601	142	13	33658012
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNA FLNB CD2AP USP24 ZNF507 MECOM POGZ AHNAK TBK1 CEP131 ARHGAP21	1.29e-06	418	142	11	34709266
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	TCOF1 GAPDH POLR2A POGZ RUVBL2 NOP14 SUGP2 NOP2 NIPBL	1.29e-06	259	142	9	30404004
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB USP13 SPRED2 MYO5A TCOF1 MYO6 PLA2G3 ASH1L TRIOBP POGZ ARMCX4 RFX5 PLEKHH1 FRY YLPM1 ALDOA NIPBL ARHGAP21 ATP5F1A	1.31e-06	1285	142	19	35914814
Pubmed	Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.	MYO5A MYO6 GRIP1	1.32e-06	6	142	3	25673849
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	TCOF1 POLR2A POGZ EMSY NOP14 MDC1 YLPM1 TPX2 SAFB2 NOP2	1.52e-06	341	142	10	32971831
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	FLNA FLNB TCOF1 GAPDH ACLY RUVBL2	1.60e-06	87	142	6	24169447
Pubmed	Interaction network of human early embryonic transcription factors.	GAPDH MECOM POGZ EMSY KMT2C YEATS4 TBK1 MDC1 CPVL NIPBL	1.97e-06	351	142	10	38297188
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	FLNA RBM15 TCOF1 GAPDH ACLY POLR2A SAFB NOP14 SAFB2 NOP2 ATP5F1A	2.17e-06	441	142	11	31239290
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MYO5A TCOF1 TRIOBP MPDZ ARMCX4 GABBR2 SHANK3 EMSY FRY TBK1 YLPM1 SAFB2 CEP131 NOP2 NIPBL ARHGAP21	2.21e-06	963	142	16	28671696
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	FLNA FLNB ACLY POLR2A CPS1 NOP2 ATP5F1A	2.25e-06	144	142	7	35681168
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB FLNC	2.30e-06	7	142	3	16076904
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RBM15 MYO6 POLR2A TRIOBP RUVBL2 EMSY MYO5C TPX2 NOP2 ARHGAP21	2.53e-06	361	142	10	30344098
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	TCOF1 SAFB SUGP2 MDC1 YLPM1 TPX2 NOP2	2.70e-06	148	142	7	32538781
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB FLNC	3.68e-06	8	142	3	17145501
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	EPS8 FLNA FLNB TCOF1 GAPDH POLR2A POGZ RUVBL2 SAFB NOP14 MDC1 ALDOA NOP2	4.02e-06	670	142	13	22990118
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	FLNA FLNB GAPDH ACLY ALDOA ATP5F1A	4.55e-06	104	142	6	36055981
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	FLNA FLNB MYO5A GAPDH MYO6 ACLY OAS3 CPS1 AHNAK ALDOA NOP2 ATP5F1A	5.04e-06	580	142	12	35676659
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB FLNC	5.50e-06	9	142	3	11807098
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	FLNA FLNB MYO5A GAPDH ACLY OLA1 SUCLA2 RUVBL2 NRP2 GANAB AHNAK ALDOA ATP5F1A GOT1	5.74e-06	803	142	14	36517590
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	FLNC RBM15 MYO5A MYO6 POLR2A CLPX RUVBL2 RBM15B NID1	6.05e-06	313	142	9	38270169
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPS8 FLNA FLNB FLNC MYO5A GAPDH MYO6 ACLY DGKB OLA1 SUCLA2 KRT79 SHANK3 SAFB SUGP2 ALDOA ARHGAP21 ATP5F1A GOT1	6.21e-06	1431	142	19	37142655
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RBM15 MYO5A POLR2A TRIOBP CLPX GPRIN1 YEATS4 GANAB NOP14 PTPRM AHNAK SBF2 YLPM1 CEP131 CPVL ATP5F1A	6.52e-06	1049	142	16	27880917
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MYO6 POLR2A RECQL GMPR2 CPS1 CLPX SUCLA2 RUVBL2 RPAP1 SUGP2 FDXR NIPBL ATP5F1A	6.84e-06	704	142	13	29955894
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNA FLNB FLNC UBTD2 CLTCL1 MYO5A ASH1L CLPX KRT79 SAFB NOP14 KIAA0825 AHNAK YLPM1 SAFB2 PABPC1L NIPBL ARHGAP21 ATP5F1A	6.92e-06	1442	142	19	35575683
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RBM15 TCOF1 GAPDH MECOM SAFB NOP14 SUGP2 MDC1 YLPM1 RBM15B NOP2 ATP5F1A	7.70e-06	605	142	12	28977666
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	FLNA FLNB FLNC CD2AP CSMD2 SHANK3 TPX2 MYO18B TAL1	9.03e-06	329	142	9	17474147
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBM15 POGZ RUVBL2 KMT2C SAFB AHNAK RBM15B SAFB2	9.61e-06	251	142	8	31076518
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	FLNA FLNB POLR2A SAFB AHNAK MDC1 TPX2 SAFB2 NIPBL	9.70e-06	332	142	9	32786267
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	FLNB RBM15 TCOF1 CPS1 POLR1G RUVBL2 SAFB NOP14 SUGP2 MDC1 TPX2 RBM15B SAFB2 NOP2	1.05e-05	847	142	14	35850772
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNA FLNB FLNC	1.07e-05	11	142	3	36579465
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	FLNA FLNB MYO5A TCOF1 GAPDH MYO6 RUVBL2 SHANK3 SAFB AHNAK ALDOA ATP5F1A	1.08e-05	626	142	12	33644029
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNA FLNB TCOF1 ACLY POLR2A CD2AP AHNAK TPX2	1.11e-05	256	142	8	33397691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS8 MYO5A POLR2A PDZK1 CD2AP TRIOBP MPDZ OLA1 CMSS1 POLR1G EMSY KMT2C NOP14 MDC1 TPX2 RBM15B CEP131 NIPBL ATP5F1A	1.17e-05	1497	142	19	31527615
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	FLNA RBM15 TCOF1 GAPDH RUVBL2 AHNAK MDC1 TPX2 NIPBL	1.17e-05	340	142	9	24332808
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNA FLNB FLNC USP24 OAS3 CPS1 CLPX GANAB ALDOA	1.29e-05	344	142	9	30333137
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TCOF1 POLR2A ASH1L MECOM OAS3 POGZ CLPX C11orf16 POLR1G MAST2 RUVBL2 YEATS4 EML5 SUGP2 TBK1 NOVA2	1.40e-05	1116	142	16	31753913
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	PDZK1 MPDZ MAST2 ARHGAP21	1.42e-05	36	142	4	26053890
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	FLNB CLTCL1 MYO6 ACLY SUCLA2 RUVBL2 ITIH2 GANAB AHNAK PABPC1L ALDOA ATP5F1A	1.50e-05	647	142	12	26618866
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	FLNA FLNC MYO6 CD2AP RECQL CPS1 EMSY SAFB AHNAK ALDOA	1.54e-05	444	142	10	34795231
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	EPS8 RBM15 MPDZ MAST2 RUVBL2 GRIP1 TBK1 CCSER2 CEP131 CPVL	1.60e-05	446	142	10	24255178
Interaction	CIT interactions	FLNA FLNB FLNC RBM15 CLTCL1 TCOF1 GAPDH MYO6 POLR2A ASH1L OAS3 RECQL POGZ GMPR2 CPS1 CLPX POLR1G RUVBL2 SHANK3 SAFB GANAB NOP14 SUGP2 AHNAK MDC1 TPX2 SAFB2 PABPC1L NOP2 NIPBL ATP5F1A	1.18e-08	1450	139	31	int:CIT
Interaction	H3C1 interactions	GAPDH MYO6 POLR2A ASH1L MECOM RECQL POGZ OLA1 CLPX POLR1G GPRIN1 RUVBL2 RFX5 ITIH2 GRIP1 KMT2C YEATS4 TMEM132D AHNAK MDC1 TPX2 NOP2 CPVL NIPBL	1.19e-08	901	139	24	int:H3C1
Interaction	OBSL1 interactions	FLNA FLNB FLNC RBM15 TCOF1 GAPDH ACLY POLR2A CMSS1 POLR1G RUVBL2 SAFB GANAB SUGP2 FAM222A AHNAK MDC1 YLPM1 SAFB2 ALDOA NOP2 NIPBL ATP5F1A	5.55e-08	902	139	23	int:OBSL1
Interaction	YAP1 interactions	FLNA FLNB CLTCL1 TCOF1 GAPDH MYO6 ACLY POLR2A CD2AP TRIOBP MPDZ POGZ KRT79 RUVBL2 KMT2C YEATS4 AHNAK TBK1 MDC1 YLPM1 TPX2 ALDOA CPVL ATP5F1A	4.48e-07	1095	139	24	int:YAP1
Interaction	CDC73 interactions	FLNA FLNB FLNC CLTCL1 GAPDH POLR2A RECQL USP37 POLR1G RUVBL2 RFX5 KMT2C ALDOA ATP5F1A	4.74e-07	386	139	14	int:CDC73
Interaction	DTX3 interactions	FLNA FLNB FLNC MYO5A ITIH2 GANAB AHNAK ATP5F1A	8.24e-07	108	139	8	int:DTX3
Interaction	SIRT7 interactions	FLNA FLNB FLNC RBM15 MYO5A TCOF1 ACLY POLR2A USP24 RECQL POGZ GANAB NOP14 SUGP2 AHNAK MDC1 YLPM1 NOP2 NIPBL	8.81e-07	744	139	19	int:SIRT7
Interaction	LAD1 interactions	FLNA FLNB FLNC TOPAZ1 OLA1 GOT1	1.90e-06	54	139	6	int:LAD1
Interaction	CCDC8 interactions	FLNA FLNB MYO5A GAPDH ACLY POLR2A RUVBL2 MYO5C RPAP1 SUGP2 FAM222A AHNAK TBK1 CEP131 NOP2 NIPBL ATP5F1A	2.86e-06	656	139	17	int:CCDC8
Interaction	PRC1 interactions	FLNA FLNB FLNC RBM15 CLTCL1 GAPDH POLR2A RECQL CPS1 CMSS1 RUVBL2 SHANK3 NRP2 SAFB AHNAK MDC1 TPX2 SAFB2 PABPC1L NOP2 ATP5F1A	3.28e-06	973	139	21	int:PRC1
Interaction	PPP1R9B interactions	EPS8 FLNA MYO5A TCOF1 GAPDH MYO6 ACLY MECOM RECQL SUCLA2 SHANK3 SYDE2 NID1 ALDOA ATP5F1A GOT1	6.82e-06	626	139	16	int:PPP1R9B
Interaction	ACE2 interactions	FLNA FLNB RBM15 TCOF1 GAPDH MYO6 ACLY PDZK1 TRIOBP MAST2 RUVBL2 SHANK3 SAFB GANAB NOP14 MDC1 YLPM1 CCSER2 SAFB2 ALDOA NOP2 ATP5F1A	6.91e-06	1106	139	22	int:ACE2
Interaction	KIF23 interactions	FLNA FLNB MYO5A GAPDH ACLY CD2AP CPS1 CLPX MAST2 RFX5 MYO5C FRY SAFB NOP14 SUGP2 AHNAK SAFB2 PABPC1L NOP2 ARHGAP21 ATP5F1A	8.01e-06	1031	139	21	int:KIF23
Interaction	TNIP1 interactions	FLNA FLNB RBM15 MYO5A TCOF1 GAPDH MYO6 ACLY CPS1 CMSS1 POLR1G MYO5C SAFB GANAB AHNAK TBK1 MDC1 TPX2 SAFB2 ALDOA NOP2 CPVL ATP5F1A	9.59e-06	1217	139	23	int:TNIP1
Interaction	CEBPA interactions	FLNA RBM15 GAPDH ACLY POLR2A ZNF507 RECQL POGZ OLA1 CMSS1 RUVBL2 RFX5 EMSY KMT2C SAFB NOP14 SUGP2 AK5 TPX2 SAFB2 ALDOA NOP2 NIPBL	1.38e-05	1245	139	23	int:CEBPA
Interaction	FGD5 interactions	FLNA FLNB FLNC GAPDH MYO6 ACLY AHNAK ALDOA ATP5F1A	1.38e-05	207	139	9	int:FGD5
Interaction	SUMO2 interactions	FLNA FLNB GAPDH POLR2A POGZ MAST2 SAFB AHNAK TBK1 MDC1 TPX2 SAFB2 ALDOA NOP2 NIPBL	1.46e-05	591	139	15	int:SUMO2
Interaction	SMC5 interactions	FLNA RBM15 GAPDH POLR2A CD2AP POGZ RFX5 EMSY SAFB SUGP2 AHNAK MDC1 YLPM1 TPX2 RBM15B SAFB2 ALDOA NOP2 NIPBL ATP5F1A	1.76e-05	1000	139	20	int:SMC5
Interaction	CHMP4C interactions	FLNA FLNB FLNC CLTCL1 GAPDH ACLY HS3ST5 CPS1 RUVBL2 SAFB GANAB AHNAK MDC1 SAFB2 ALDOA NOP2	2.15e-05	687	139	16	int:CHMP4C
Interaction	KCNA3 interactions	FLNB TCOF1 GAPDH MYO6 ACLY CD2AP USP24 MPDZ GPRIN1 RUVBL2 MYO5C GRIP1 KMT2C GANAB AHNAK ALDOA ARHGAP21 ATP5F1A	3.14e-05	871	139	18	int:KCNA3
Interaction	SNIP1 interactions	TCOF1 GAPDH POLR2A POGZ OLA1 RUVBL2 NOP14 SUGP2 TPX2 RBM15B NOP2 NIPBL	3.29e-05	417	139	12	int:SNIP1
Interaction	RECQL interactions	RBM15 TCOF1 MYO6 RECQL POGZ RUVBL2 SAFB MDC1 NOP2 ATP5F1A	3.30e-05	289	139	10	int:RECQL
Interaction	ISG15 interactions	FLNA FLNB MYO5A GAPDH MYO6 ACLY RUVBL2 MYO5C GANAB AHNAK RBM15B ALDOA ATP5F1A	3.87e-05	494	139	13	int:ISG15
Interaction	KLF16 interactions	ZNF507 MECOM POGZ CLPX RUVBL2 EMSY YEATS4 GANAB NOP14 TPX2 CPVL NIPBL	3.96e-05	425	139	12	int:KLF16
Interaction	SLX4 interactions	FLNA RBM15 GAPDH POLR2A POGZ EMSY SAFB NOP14 SUGP2 MDC1 TPX2 ALDOA NIPBL ATP5F1A	4.25e-05	572	139	14	int:SLX4
Interaction	NAA40 interactions	FLNA TCOF1 GAPDH MYO6 ACLY POLR2A GPRIN1 EMSY SAFB SUGP2 AHNAK YLPM1 TPX2 SAFB2 ALDOA NOP2 NIPBL ARHGAP21 ATP5F1A	4.31e-05	978	139	19	int:NAA40
Interaction	CAPZA2 interactions	FLNA FLNB CLTCL1 MYO5A MYO6 CD2AP TRIOBP SHANK3 MYO5C AHNAK CPVL ARHGAP21	4.43e-05	430	139	12	int:CAPZA2
Interaction	PIH1D1 interactions	FLNA FLNB TCOF1 GAPDH ACLY POLR2A USP24 RECQL CPS1 POLR1G RUVBL2 AHNAK SBF2 ALDOA NOP2 ATP5F1A	4.54e-05	731	139	16	int:PIH1D1
Interaction	PPP1CC interactions	FLNA RBM15 MYO6 POLR2A TRIOBP RUVBL2 SHANK3 EMSY MYO5C SNCAIP YLPM1 TPX2 SAFB2 CEP126 NOP2 ARHGAP21	5.08e-05	738	139	16	int:PPP1CC
Interaction	AR interactions	FLNA MYO5A GAPDH MYO6 ACLY RECQL RUVBL2 RFX5 EMSY MYO5C GRIP1 KMT2C SUGP2 MDC1 YLPM1 TPX2 CEP131 NIPBL ATP5F1A	5.22e-05	992	139	19	int:AR
Interaction	UBC interactions	FLNB USP13 MYO5A TCOF1 MYO6 USP24 RECQL OLA1 USP37 SUCLA2 AHNAK ATP5F1A	6.29e-05	446	139	12	int:UBC
Interaction	AIMP2 interactions	EPS8 FLNA FLNB FLNC GAPDH ACLY CD2AP RUVBL2 SAFB CEP126 ALDOA ATP5F1A	6.29e-05	446	139	12	int:AIMP2
Interaction	PINK1 interactions	FLNA FLNB FLNC RBM15 COL15A1 GAPDH MYO6 ACLY GANAB SNCAIP SUGP2 AHNAK ALDOA NOP2 ATP5F1A	7.17e-05	679	139	15	int:PINK1
Interaction	CUL7 interactions	FLNA FLNB RBM15 TCOF1 GAPDH ACLY POLR2A OLA1 RUVBL2 SAFB GANAB AHNAK MDC1 RBM15B SAFB2 NOP2 ATP5F1A	7.37e-05	845	139	17	int:CUL7
Interaction	NUPR1 interactions	EPS8 FLNA FLNB RBM15 MYO5A MYO6 ACLY RECQL RUVBL2 SAFB AHNAK MDC1 YLPM1 SAFB2 NOP2	7.66e-05	683	139	15	int:NUPR1
Interaction	AGR2 interactions	FLNA FLNB FLNC CLTCL1 GAPDH ACLY POLR2A ASH1L GBP3 POGZ OLA1 KRT79 RUVBL2 SAFB GANAB AHNAK ALDOA ATP5F1A	7.73e-05	934	139	18	int:AGR2
Interaction	CDK9 interactions	FLNA FLNB MYO5A TCOF1 GAPDH POLR2A RECQL RUVBL2 SAFB GANAB TBK1 RBM15B TAL1 NOP2 ATP5F1A	7.91e-05	685	139	15	int:CDK9
Interaction	PPP1R12A interactions	FLNA CLTCL1 GAPDH ASH1L TRIOBP RECQL SHANK3 MYO5C SYDE2 AHNAK	8.15e-05	322	139	10	int:PPP1R12A
Interaction	HS3ST4 interactions	CLTCL1 ITIH2 HS3ST2	8.73e-05	13	139	3	int:HS3ST4
Interaction	HNRNPA1 interactions	FLNA RBM15 GAPDH MYO6 RECQL KRT79 RUVBL2 SAFB CD4 CSF2 RPAP1 SUGP2 TBK1 YLPM1 RBM15B SAFB2 ALDOA ATP5F1A	8.96e-05	945	139	18	int:HNRNPA1
Interaction	ACTC1 interactions	EPS8 FLNA FLNB TCOF1 GAPDH MYO6 CD2AP RUVBL2 MYO5C YEATS4 MDC1 YLPM1 TPX2 NOP2 ATP5F1A	9.15e-05	694	139	15	int:ACTC1
Interaction	KIF20A interactions	FLNA FLNB FLNC CLTCL1 MYO6 CPS1 POLR1G RUVBL2 EMSY SAFB SUGP2 AHNAK MDC1 YLPM1 TPX2 SAFB2 PABPC1L NOP2 ATP5F1A	1.13e-04	1052	139	19	int:KIF20A
Interaction	ZC3H18 interactions	RBM15 MYO5A TCOF1 GAPDH RECQL CMSS1 POLR1G RUVBL2 SAFB NOP14 SUGP2 RBM15B SAFB2 ALDOA NOP2 ATP5F1A NOVA2	1.16e-04	877	139	17	int:ZC3H18
Interaction	BRCA1 interactions	FLNA FLNB FLNC TCOF1 GAPDH ACLY POLR2A RECQL OLA1 CLPX USP37 RUVBL2 EMSY GANAB AHNAK MDC1 TPX2 ALDOA NOP2 NIPBL ARHGAP21	1.31e-04	1249	139	21	int:BRCA1
Interaction	PHF21A interactions	FLNA FLNB USP24 ZNF507 MECOM YEATS4 AHNAK TBK1 CEP131 ARHGAP21	1.37e-04	343	139	10	int:PHF21A
Interaction	FOXO1 interactions	TCOF1 CD2AP RECQL POLR1G ITIH2 GPR179 SAFB AHNAK ALDOA ATP5F1A	1.50e-04	347	139	10	int:FOXO1
Interaction	ACOT7 interactions	TCOF1 GAPDH OLA1 SHANK3 GANAB ATP5F1A GOT1	1.67e-04	168	139	7	int:ACOT7
Interaction	MYO15A interactions	EPS8 USP13 SHANK3	1.68e-04	16	139	3	int:MYO15A
Interaction	ITGB3 interactions	EPS8 FLNA FLNB FLNC OAS3 GANAB NID1	1.80e-04	170	139	7	int:ITGB3
Interaction	RNF123 interactions	TICRR FLNB FLNC GAPDH TOPAZ1 ACLY POLR2A CSMD2 GPRIN1 KMT2C FRY RPAP1 GALNT11 SYDE2 AHNAK TBK1	1.82e-04	824	139	16	int:RNF123
Interaction	WAPL interactions	FLNA USP13 RBM15 USP37 RUVBL2 ZSWIM9 NIPBL	2.01e-04	173	139	7	int:WAPL
Interaction	EP300 interactions	FLNA RBM15 CLTCL1 GAPDH ACLY POLR2A USP24 ABCC9 OLA1 CLPX RUVBL2 GRIP1 SAFB GANAB NOP14 MDC1 YLPM1 TPX2 SAFB2 ALDOA TAL1 NOP2	2.37e-04	1401	139	22	int:EP300
Interaction	NR2C2 interactions	FLNA RBM15 TMPRSS15 TCOF1 GAPDH ACLY CD2AP USP24 RECQL CLPX POLR1G SUCLA2 RUVBL2 EMSY SAFB GANAB NOP14 AHNAK SAFB2 NOP2 NIPBL ATP5F1A	2.41e-04	1403	139	22	int:NR2C2
Interaction	RICTOR interactions	FLNA FLNB FLNC MYO5A GAPDH MYO6 ACLY CD2AP CPS1 CLPX RUVBL2 SUGP2 AHNAK ALDOA ATP5F1A	2.43e-04	759	139	15	int:RICTOR
Interaction	AURKB interactions	FLNA CLTCL1 CPS1 USP37 POLR1G RUVBL2 GANAB SUGP2 AHNAK MDC1 TPX2 PABPC1L CEP131 NOP2 ATP5F1A	2.50e-04	761	139	15	int:AURKB
Interaction	CHD4 interactions	RBM15 TCOF1 GAPDH MECOM POGZ RUVBL2 SAFB GANAB NOP14 SUGP2 AHNAK MDC1 YLPM1 RBM15B TAL1 NOP2 ATP5F1A	2.56e-04	938	139	17	int:CHD4
Interaction	ERLEC1 interactions	TPST2 TRIOBP MYO5C SAFB CLN5 CPVL	2.63e-04	128	139	6	int:ERLEC1
Interaction	BAP1 interactions	FLNA FLNB FLNC MYO5A TCOF1 GAPDH MYO6 ACLY CD2AP MPDZ RECQL CPS1 POLR1G RUVBL2 KMT2C GANAB AHNAK ALDOA CPVL ATP5F1A GOT1	2.63e-04	1314	139	21	int:BAP1
Interaction	CTTN interactions	FLNA FLNB RBM15 MYO5A MYO6 ACLY CD2AP SHANK3 MYO5C AHNAK RBM15B	2.93e-04	450	139	11	int:CTTN
Interaction	BTRC interactions	FLNA PTTG1 CLTCL1 TCOF1 POLR2A CLPX USP37 MAST2 KRT79 SAFB GANAB EML5 TBK1 CPVL ATP5F1A	3.03e-04	775	139	15	int:BTRC
Interaction	RPA4 interactions	FLNA TCOF1 CD2AP POGZ RUVBL2 SAFB SUGP2 AHNAK TPX2 SAFB2 ALDOA	3.05e-04	452	139	11	int:RPA4
Interaction	OXCT1 interactions	TCOF1 SUCLA2 AHNAK FDXR ATP5F1A GOT1	3.23e-04	133	139	6	int:OXCT1
Interaction	CDK2 interactions	FLNA FLNB FLNC MYO5A TCOF1 GAPDH MYO6 POLR2A USP37 POLR1G GANAB AHNAK ALDOA NOP2 ATP5F1A	3.38e-04	783	139	15	int:CDK2
Interaction	SPDL1 interactions	FLNA FLNB FLNC THNSL1 CLTCL1 GAPDH AHNAK YLPM1 CEP126	3.45e-04	315	139	9	int:SPDL1
Interaction	MYO19 interactions	FLNA FLNB CLTCL1 MYO5A MYO6 MYO5C AHNAK ARHGAP21	3.68e-04	252	139	8	int:MYO19
Interaction	SYNPO interactions	FLNA FLNB MYO5A MYO6 SHANK3 MYO5C ARHGAP21	3.78e-04	192	139	7	int:SYNPO
Interaction	XDH interactions	GRIP1 NIPBL GOT1	3.90e-04	21	139	3	int:XDH
Interaction	SIRT6 interactions	FLNA FLNB TCOF1 GAPDH ACLY POLR2A RUVBL2 MDC1 YLPM1 TPX2 CCSER2 CEP131 NOP2	4.14e-04	628	139	13	int:SIRT6
Interaction	PPP1CB interactions	FLNA FLNB MYO5A MYO6 TRIOBP USP37 MYO5C SAFB YLPM1 SAFB2 ARHGAP21	4.16e-04	469	139	11	int:PPP1CB
Interaction	FBLIM1 interactions	FLNA FLNB FLNC EMSY	4.21e-04	51	139	4	int:FBLIM1
Interaction	SNCA interactions	FLNA FLNB GAPDH ACLY POLR2A USP24 OLA1 GPRIN1 RUVBL2 GRIP1 SNCAIP SUGP2 AHNAK ARHGAP21	4.38e-04	716	139	14	int:SNCA
Interaction	GAGE5 interactions	MYO5A TRIOBP MYO5C TPX2	4.54e-04	52	139	4	int:GAGE5
Interaction	TOP3B interactions	TPST2 FLNA FLNC RBM15 CLTCL1 SPRED2 MYO6 POLR2A CLPX MAST2 KMT2C SAFB RPAP1 SUGP2 AHNAK SBF2 MDC1 SAFB2 CEP131 NOP2 CPVL ARHGAP21	4.59e-04	1470	139	22	int:TOP3B
Interaction	ERI2 interactions	FLNC ERI2	4.66e-04	5	139	2	int:ERI2
Interaction	KLF8 interactions	MECOM POGZ CLPX RUVBL2 EMSY GANAB NOP14 CPVL NIPBL	4.72e-04	329	139	9	int:KLF8
Interaction	HNRNPD interactions	FLNA USP13 GAPDH ACLY POLR2A USP24 GPRIN1 SAFB CD4 EML5 AHNAK SBF2 YLPM1	4.80e-04	638	139	13	int:HNRNPD
Interaction	HSPB2 interactions	FLNC GAPDH ABCC9 POGZ NID1 ALDOA ATP5F1A	4.83e-04	200	139	7	int:HSPB2
Interaction	MYO1E interactions	FLNA MYO5A RECQL RUVBL2 MYO5C TPX2 ARHGAP21	5.12e-04	202	139	7	int:MYO1E
Interaction	PHLPP1 interactions	FLNA FLNB RBM15 TCOF1 ACLY POLR2A CD2AP AHNAK TPX2	5.15e-04	333	139	9	int:PHLPP1
Interaction	KALRN interactions	MYO5A GPRIN1 SHANK3 SNCAIP ATP5F1A	5.37e-04	96	139	5	int:KALRN
Interaction	ARHGAP24 interactions	FLNA GAPDH ACLY GMPR2 OLA1 CPS1 CLPX GANAB NOP2 ATP5F1A GOT1	5.60e-04	486	139	11	int:ARHGAP24
Interaction	HSPB7 interactions	FLNA FLNB FLNC	5.84e-04	24	139	3	int:HSPB7
Interaction	MDC1 interactions	EPS8 FLNA FLNB USP13 POLR2A RECQL POGZ EMSY MDC1 TPX2	6.08e-04	414	139	10	int:MDC1
Interaction	MATR3 interactions	MECOM RUVBL2 SAFB GANAB SUGP2 GALNT11 YLPM1 RBM15B SAFB2 NOP2 ATP5F1A NOVA1 NOVA2	6.14e-04	655	139	13	int:MATR3
Interaction	HDAC1 interactions	FLNA FLNB GAPDH CD2AP USP24 ZNF507 MECOM USP37 POLR1G RUVBL2 EMSY GRIP1 GANAB AHNAK TBK1 CEP131 TAL1 ARHGAP21	6.20e-04	1108	139	18	int:HDAC1
GeneFamily	PDZ domain containing	PDZK1 MPDZ MAST2 SHANK3 GRIP1 AHNAK ARHGAP21	5.80e-06	152	82	7	1220
GeneFamily	Sulfotransferases, membrane bound	TPST2 HS3ST5 HS3ST6 HS3ST2	2.32e-05	37	82	4	763
GeneFamily	Myosins, class V	MYO5A MYO5C	6.08e-05	3	82	2	1100
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	ASH1L MECOM KMT2C	4.86e-04	34	82	3	487
GeneFamily	INO80 complex \|SRCAP complex	RUVBL2 YEATS4	7.17e-04	9	82	2	1329
GeneFamily	Ubiquitin specific peptidases	USP13 USP24 USP37	2.10e-03	56	82	3	366
GeneFamily	RNA binding motif containing	RBM15 SAFB RBM15B SAFB2 PABPC1L	2.83e-03	213	82	5	725
Coexpression	GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN	TCOF1 CD2AP USP24 POGZ POLR1G NOP14 EML5 MDC1	5.01e-06	175	141	8	M2940
Coexpression	AIZARANI_LIVER_C9_LSECS_1	FLNB USP13 MYO6 TRIOBP SHANK3 NRP2 CD4 NID1 TAL1 NOVA2	6.15e-06	304	141	10	M39113
Coexpression	GSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_UP	USP13 TMPRSS15 COL15A1 SPRED2 MYO5A USP24 CCR2 RBM15B	1.28e-05	199	141	8	M8425
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	COL15A1 MPDZ POLR1G ZNF385D FRY MDC1 NID1 PLCXD3 NOVA2	9.47e-09	187	142	9	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-tip_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 MYO6 MPDZ MECOM SHANK3 NRP2 PTPRM NID1 NOVA2	1.49e-08	197	142	9	b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	TPST2 FLNB CD2AP MECOM SHANK3 ADGRG6 AK5 HS3ST2	2.04e-07	193	142	8	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MYO6 MPDZ ABCC9 SHANK3 ADGRG6 NRP2 NID1 NOVA2	2.38e-07	197	142	8	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 FLNA FLNC DGKB CPS1 PANK1 AK5 MYO18B	2.38e-07	197	142	8	470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 MYO6 MPDZ SHANK3 NRP2 PTPRM NID1 NOVA2	2.47e-07	198	142	8	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 MYO6 MPDZ SHANK3 NRP2 PTPRM NID1 NOVA2	2.47e-07	198	142	8	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	10x3'2.3-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPDZ ABCC9 SHANK3 ADGRG6 NRP2 PTPRM NID1 NOVA2	2.57e-07	199	142	8	41f046646fff65b7e51b63d3204f76ef32054781
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPDZ ABCC9 SHANK3 ADGRG6 NRP2 PTPRM NID1 NOVA2	2.57e-07	199	142	8	ef7f7f7c861827574b120f48cf4052c563929081
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 MPDZ ABCC9 SHANK3 NRP2 PTPRM NID1 NOVA2	2.67e-07	200	142	8	77ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 MYO5A OAS2 ABCA9 MSR1 CD4 GOT1	9.11e-07	162	142	7	228e33678c7f963b3032a218333f206e5fff1292
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-4\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TCOF1 OLA1 CMSS1 POLR1G SAFB TPX2 PABPC1L	1.07e-06	166	142	7	52293b8a74d46e6161fb6a2e7e86e51fd9e89a5b
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	FLNC MYO5A NRP2 MSR1 CD4 MYO18B CPVL	1.26e-06	170	142	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PTTG1 OAS2 POLR1G RFX5 TPX2 PABPC1L GOT1	1.77e-06	179	142	7	5787ffba96918db80256ced076a455a84ba01384
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MYO6 ITPRID1 GABBR2 SHANK3 PTPRM PLCXD3 NOVA2	1.91e-06	181	142	7	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 COL15A1 MECOM ABCA9 ZNF385D NID1 NOVA1	1.98e-06	182	142	7	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	MPDZ MECOM SHANK3 SLC2A5 ZNF385D MDC1 TAL1	2.06e-06	183	142	7	6c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCOF1 CD2AP ABCA9 MSR1 CCR2 AHNAK NIPBL	2.21e-06	185	142	7	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB MECOM ADGRG6 SNCAIP PTPRM FLRT1 CPVL	2.29e-06	186	142	7	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO6 GBP3 OAS2 OAS3 SHANK3 PTPRM NOVA1	2.37e-06	187	142	7	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MECOM SHANK3 ADGRG6 ZNF385D PTPRM PLCXD3 NOVA2	2.37e-06	187	142	7	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB COL15A1 GBP3 ARMCX4 PLEKHH1 FRY PTPRM	2.37e-06	187	142	7	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB COL15A1 GBP3 ARMCX4 PLEKHH1 FRY PTPRM	2.37e-06	187	142	7	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB CD2AP USP24 DGKB MECOM ABCA9 MYO5C	2.37e-06	187	142	7	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	COL15A1 MYO5A TCOF1 MECOM ERI2 ZNF385D PLCXD3	2.37e-06	187	142	7	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 MECOM SHANK3 ITIH2 MYO5C PTPRM TAL1	2.55e-06	189	142	7	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO6 SHANK3 FRY PTPRM PLCXD3 TAL1 NOVA2	2.55e-06	189	142	7	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	FLNB MECOM SHANK3 ADGRG6 PTPRM AK5 HS3ST2	2.55e-06	189	142	7	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB CD2AP USP24 DGKB MECOM ABCA9 MYO5C	2.55e-06	189	142	7	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLNC COL15A1 ABCC9 ZNF385D FRY PLCXD3 MYO18B	2.64e-06	190	142	7	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	MECOM SHANK3 MYO5C ADGRG6 NRP2 ZNF385D PTPRM	2.64e-06	190	142	7	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	TPST2 FLNB MECOM SHANK3 ADGRG6 PTPRM NOVA2	2.73e-06	191	142	7	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OAS2 OAS3 CCR2 AHNAK ALDOA CPVL ATP5F1A	2.92e-06	193	142	7	4fb020f11fd7aff06952bfeaabc79b2c7b8873f6
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OAS2 OAS3 CCR2 AHNAK ALDOA CPVL ATP5F1A	3.02e-06	194	142	7	885355ebe98e974f841cc59dce3b5228c642c5d0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL15A1 MECOM SHANK3 ADGRG6 FRY PTPRM NID1	3.13e-06	195	142	7	4658fb197657d7692ee344ae76b11b0210c418ba
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EPS8 MYO5A ABCA9 ADGRG6 NRP2 MSR1 CD4	3.13e-06	195	142	7	4008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 COL15A1 ABCC9 ABCA9 SNCAIP NID1 PLCXD3	3.13e-06	195	142	7	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPDZ ABCC9 SHANK3 ADGRG6 NRP2 NID1 NOVA2	3.35e-06	197	142	7	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TPST2 SHANK3 ADGRG6 ZNF385D PLCXD3 TAL1 NOVA2	3.35e-06	197	142	7	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	3'-Child09-12-SmallIntestine-Endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 MECOM SHANK3 NRP2 PTPRM TAL1 NOVA2	3.35e-06	197	142	7	86a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	FLNA OAS2 OAS3 KMT2C CD4 AHNAK CPVL	3.46e-06	198	142	7	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC SHANK3 NRP2 ZNF385D SNCAIP TAL1 NOVA2	3.46e-06	198	142	7	9ab0db78394e730f6866b2db80047149024ad5f6
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	EPS8 COL15A1 MYO5A MECOM ERI2 MYO5C ZNF385D	3.46e-06	198	142	7	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC SHANK3 NRP2 ZNF385D SNCAIP TAL1 NOVA2	3.46e-06	198	142	7	e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLNB SHANK3 ADGRG6 ZNF385D PLCXD3 TAL1 NOVA2	3.58e-06	199	142	7	53b6a661d381b1ed3ea96e61e8bd1750de7d9fda
ToppCell	CTRL-Myeloid\|CTRL / Disease state, Lineage and Cell class	FLNA MYO5A CARD16 MSR1 CD4 PTPRM CPVL	3.58e-06	199	142	7	70b89a930709fdb91fde6f96106add8455b11618
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 MECOM SHANK3 ADGRG6 PTPRM TAL1 NOVA2	3.58e-06	199	142	7	0d63da0afa93741c37609d879941de202d9ac86c
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Bronchial_vessel\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FLNB SHANK3 ADGRG6 ZNF385D PLCXD3 TAL1 NOVA2	3.58e-06	199	142	7	9c753043024871b1f1436fc39defac4da85e10cd
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB SHANK3 ADGRG6 ZNF385D PLCXD3 TAL1 NOVA2	3.58e-06	199	142	7	d017dd91f9b10038f1f83753a766e534da2dbe89
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNB ASH1L MPDZ MECOM KMT2C PTPRM NIPBL	3.70e-06	200	142	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	10x5'v1-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPDZ ABCC9 SHANK3 ADGRG6 NRP2 PTPRM NID1	3.70e-06	200	142	7	2488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO6 GBP3 OAS2 OAS3 FRY PTPRM NOVA1	3.70e-06	200	142	7	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage-Macrophages-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TPST2 SHANK3 ADGRG6 ZNF385D PTPRM PLCXD3 NOVA2	3.70e-06	200	142	7	98f6a86fbbe5305c71dae91e7278de9813827935
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO6 GBP3 OAS2 FRY PTPRM AHNAK NOVA1	3.70e-06	200	142	7	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLNB COL15A1 SHANK3 ADGRG6 ZNF385D PLCXD3 NOVA2	3.70e-06	200	142	7	27507c4b41d45c7cc50e4993169c0302be22ee34
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Macrophages\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	TPST2 SHANK3 ADGRG6 ZNF385D PTPRM PLCXD3 NOVA2	3.70e-06	200	142	7	d7b89a721988660d8010c804916f5d0ef2520ee2
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage-Macrophages\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TPST2 SHANK3 ADGRG6 ZNF385D PTPRM PLCXD3 NOVA2	3.70e-06	200	142	7	1ed1c673184f0c6aae04f90edbb1383b1c1f64d9
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EPS8 MPDZ ABCC9 SHANK3 ADGRG6 NRP2 NID1	3.70e-06	200	142	7	ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TPST2 SHANK3 ADGRG6 ZNF385D PTPRM PLCXD3 NOVA2	3.70e-06	200	142	7	2a1ba87ca4adf351ef8fa2b3154b86a5407b8f2f
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	FLNB COL15A1 SHANK3 ADGRG6 ZNF385D PLCXD3 NOVA2	3.70e-06	200	142	7	b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB COL15A1 SHANK3 ADGRG6 ZNF385D PLCXD3 NOVA2	3.70e-06	200	142	7	2cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell	10x5'v1-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPDZ ABCC9 SHANK3 ADGRG6 NRP2 PTPRM NID1	3.70e-06	200	142	7	e786544cf6f891550c4be55ebb4928c92297b504
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 MPDZ ABCA9 SHANK3 FRY AHNAK NOVA1	3.70e-06	200	142	7	7136936d05ab344a560cf159684c881063b5430d
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	RBM15 USP24 ZNF507 ZSWIM9 AHNAK TAL1	1.36e-05	162	142	6	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 MYO5A OAS2 ABCA9 MSR1 GOT1	1.51e-05	165	142	6	cece16b03282d27fb49102eb9c104a2024efd28c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TICRR CLTCL1 HS3ST5 SLC2A5 AK5 TPX2	1.78e-05	170	142	6	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell	COVID-19_Convalescent-cDC\|COVID-19_Convalescent / Disease condition and Cell class	PTTG1 COL15A1 MSH5 ADGRG6 GRIP1 AK5	1.84e-05	171	142	6	9ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	GABBR2 SHANK3 ADGRG6 PLCXD3 TAL1 NOVA2	1.84e-05	171	142	6	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	COVID-19_Convalescent-cDC-\|COVID-19_Convalescent / Disease condition and Cell class	PTTG1 COL15A1 MSH5 ADGRG6 GRIP1 AK5	1.84e-05	171	142	6	fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TICRR PTTG1 UBTD2 ADGRG6 SUGP2 TPX2	1.84e-05	171	142	6	0eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	MECOM PRR25 SHANK3 MYO5C ADGRG6 ZNF385D	2.03e-05	174	142	6	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 HS3ST5 MECOM GPR179 MYO5C GRIP1	2.17e-05	176	142	6	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	3'_v3-blood-Hematopoietic_progenitors\|blood / Manually curated celltypes from each tissue	MPDZ MECOM SHANK3 ADGRG6 ZNF385D TAL1	2.24e-05	177	142	6	22c77077951889e63489abfabf90900655655c82
ToppCell	severe_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	MECOM PRR25 SHANK3 MYO5C ADGRG6 ZNF385D	2.24e-05	177	142	6	289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC MPDZ SHANK3 NRP2 SNCAIP TAL1	2.31e-05	178	142	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	Endothelial\|World / shred by cell class for turbinate	COL15A1 ADGRG6 NID1 PLCXD3 TAL1 NOVA2	2.38e-05	179	142	6	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GAPDH CARD16 GRIP1 CCR2 ALKBH1 CPVL	2.38e-05	179	142	6	61dbfc1b9b0344c06a68142c181cd62993556a67
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAPDH PDZK1 MEP1A PRODH2 GALNT11 ATP5F1A	2.46e-05	180	142	6	b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIP1 ZNF385D SNCAIP PTPRM PLCXD3 HS3ST2	2.54e-05	181	142	6	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP ABCA9 MSR1 CCR2 AHNAK NIPBL	2.62e-05	182	142	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB MECOM ADGRG6 SNCAIP PTPRM FLRT1	2.62e-05	182	142	6	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB MECOM ADGRG6 SNCAIP PTPRM FLRT1	2.62e-05	182	142	6	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	COVID-19_Severe-Hematopoietic_SC-HSPC\|COVID-19_Severe / Disease group, lineage and cell class	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.70e-05	183	142	6	4146b1c0e5f76d25226745abfa28f77127a444fc
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	CD2AP ASH1L GBP3 OAS2 OAS3 KMT2C	2.70e-05	183	142	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	COVID-19_Severe-Hematopoietic_SC\|COVID-19_Severe / Disease group, lineage and cell class	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.70e-05	183	142	6	92aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	a6169613c6493b947a176493f542368bfa935dab
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB MECOM ADGRG6 SNCAIP PTPRM CPVL	2.78e-05	184	142	6	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	51d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MPDZ MECOM SHANK3 MYO5C ADGRG6 ZNF385D	2.78e-05	184	142	6	26edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC9 SHANK3 NRP2 NID1 PLCXD3 NOVA1	2.87e-05	185	142	6	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC9 SHANK3 NRP2 NID1 PLCXD3 NOVA1	2.87e-05	185	142	6	049d793d043d5d434f143025de49dd210d18756c
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	EPS8 MYO6 HS3ST5 MECOM MYO5C GRIP1	2.87e-05	185	142	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
Drug	poly r(A-U	OAS2 OAS3 TBK1 TAL1	9.11e-07	13	139	4	CID000032741
Drug	meprobamate	FLNB TMPRSS15 CARD16 NRP2 MEP1A MSR1 PTPRM	1.14e-06	88	139	7	CID000004064
Drug	Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; PC3; HT_HG-U133A	PLA2G3 DGKB C11orf16 ITIH2 SLC2A5 PRODH2 CD4 AHNAK NOVA1	3.98e-06	200	139	9	6617_UP
Drug	NSC406942	CLTCL1 MYO5A GAPDH CLPX SLC2A5 MYO5C SAFB CD4 NOP14 SAFB2 ALDOA NOP2 CPVL NOVA2	9.77e-06	565	139	14	CID000001115
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB FLNC	9.79e-08	3	137	3	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB FLNC	9.79e-08	3	137	3	DOID:0111190 (implicated_via_orthology)
Disease	iritis	HS3ST5 POLR1G HS3ST6	6.35e-05	17	137	3	EFO_1000997
Disease	myopathy (implicated_via_orthology)	FLNA FLNB FLNC COL15A1	7.38e-05	48	137	4	DOID:423 (implicated_via_orthology)
Disease	Colorectal Carcinoma	FLNC TCOF1 GAPDH ERI2 ITPRID1 ABCA9 ZNF385D KMT2C CSF2 RPAP1 TPX2 NID1	1.11e-04	702	137	12	C0009402
Disease	schizophrenia, grey matter volume measurement	HS3ST5 HS3ST6	2.12e-04	5	137	2	EFO_0005420, MONDO_0005090
Disease	optic disc size measurement	TRIOBP HS3ST5 CMSS1 ZNF385D HS3ST6 ARHGAP21	4.04e-04	205	137	6	EFO_0004832
Disease	Endotoxemia	CPS1 ATP5F1A	5.88e-04	8	137	2	C0376618
Disease	Liver carcinoma	TICRR PTTG1 COL15A1 GAPDH ACLY MSH5 KMT2C TPX2 CEP131	6.25e-04	507	137	9	C2239176
Disease	albuminuria	CPS1 RPAP1 AK5 SBF2	9.82e-04	94	137	4	EFO_0004285
Disease	homocysteine measurement	CD2AP CPS1 GABBR2	1.28e-03	46	137	3	EFO_0004578
Disease	Malignant neoplasm of breast	FLNA FLNB ATP6V0B PDZK1 MECOM RECQL OLA1 EMSY SLC2A5 CSF2 FAM217B ALDOA NIPBL	1.52e-03	1074	137	13	C0006142
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	ZNF507 RPAP1 FLRT1	1.54e-03	49	137	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	EPS8 TRIOBP	1.61e-03	13	137	2	C1846647
Disease	Ischemic stroke, fibrinogen measurement	CPS1 SHANK3 IL1F10	2.15e-03	55	137	3	EFO_0004623, HP_0002140
Disease	clonal hematopoiesis mutation measurement	CARD16 MSR1 CSF2	2.15e-03	55	137	3	EFO_0020949
Disease	serum urea measurement	ASH1L MECOM CPS1 USP37 PLCXD3	2.21e-03	195	137	5	EFO_0009795
Disease	teratocarcinoma-derived growth factor 1 measurement	MYO5A CCR2	2.46e-03	16	137	2	EFO_0008297
Disease	fibrinogen measurement, factor VII measurement	CPS1 SHANK3 IL1F10	2.51e-03	58	137	3	EFO_0004619, EFO_0004623
Disease	caudal anterior cingulate cortex volume measurement	TMPRSS15 ZNF385D	2.78e-03	17	137	2	EFO_0010289
Disease	Mammary Carcinoma, Human	FLNA PDZK1 MECOM RECQL EMSY SLC2A5 CSF2 ALDOA	3.22e-03	525	137	8	C4704874
Disease	Mammary Neoplasms, Human	FLNA PDZK1 MECOM RECQL EMSY SLC2A5 CSF2 ALDOA	3.22e-03	525	137	8	C1257931
Disease	Mammary Neoplasms	FLNA PDZK1 MECOM RECQL EMSY SLC2A5 CSF2 ALDOA	3.30e-03	527	137	8	C1458155
Disease	Liver Cirrhosis, Experimental	FLNA MYO5A CPS1 PLEKHH1 PRODH2 FRY AHNAK NID1 BBOX1 GOT1	3.37e-03	774	137	10	C0023893
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	3.47e-03	19	137	2	DOID:2256 (is_implicated_in)
Disease	anorectal malformation	ZNF507 CSMD2	3.47e-03	19	137	2	MONDO_0019938
Disease	Breast Carcinoma	FLNA PDZK1 MECOM RECQL EMSY SLC2A5 CSF2 ALDOA	3.73e-03	538	137	8	C0678222
Disease	hearing loss	MYO6 TRIOBP MAST2	3.78e-03	67	137	3	EFO_0004238
Disease	venous thromboembolism, fibrinogen measurement	CPS1 SHANK3 IL1F10	3.78e-03	67	137	3	EFO_0004286, EFO_0004623
Disease	citrulline measurement	MECOM CPS1	3.85e-03	20	137	2	EFO_0009777
Disease	Prostate cancer, familial	MECOM EMSY MSR1	4.10e-03	69	137	3	C2931456
Disease	rheumatoid arthritis, ulcerative colitis	EMSY CCR2	4.24e-03	21	137	2	EFO_0000685, EFO_0000729
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	CSMD2 POLR1G TMEM132D	4.44e-03	71	137	3	EFO_0004735, EFO_0007965
Disease	perceived unattractiveness to mosquitos measurement	MEP1A CSF2 NID1	4.62e-03	72	137	3	EFO_0008380

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKLGPATALGNSGRV	nan	106	Q6ZS49
NGSGTIKAFPRAGVK	ZNF385D	236	Q9H6B1
ESGVQKGLIKSFPGR	C2orf16	856	Q68DN1
GKRTKLSPAAVQVGI	FAM222A	131	Q5U5X8
RRKPKGLSGALQEVG	ERI2	191	A8K979
RGRKPKTVLNGILSG	ASH1L	1051	Q9NR48
PGSIKNGTRVGSDLK	CSMD2	1561	Q7Z408
KSNILLLGPTGSGKT	CLPX	286	O76031
AARGKGPGAQKVIKS	ALKBH1	51	Q13686
GDTKPTAGQVILKGS	ABCA9	1341	Q8IUA7
ISKVIPGNGKLLLGS	ADGRG6	281	Q86SQ4
VARGQGTGKPREKLV	FDXR	466	P22570
GIKVDKGVVPLAGTN	ALDOA	106	P04075
GQVGKFKNGTLILSP	C1orf131	266	Q8NDD1
GTPGRIKELVKQGGL	CMSS1	211	Q9BQ75
QGDVKGPQVALKGSR	AHNAK	526	Q09666
IKPGQKVGICGRTGS	ABCC9	1336	O60706
ASGSVTQPKKIRGIG	CD2AP	201	Q9Y5K6
QGRSGLTPEREGKVK	CACNG6	26	Q9BXT2
SQGEVLPGAKNKIRG	ARMCX4	716	Q5H9R4
NAIDGKGPIGSKTRR	ATP5F1A	156	P25705
KITAPGLGKGQLVNL	PRODH2	46	Q9UF12
KQAAGVISLPVGGSK	RBM15B	831	Q8NDT2
KQKQAAGVISLPVGG	RBM15	896	Q96T37
GAGPLARGERKKSVV	RFX5	296	P48382
TSLKIGIVGLPNVGK	OLA1	21	Q9NTK5
RGLPGSFIKEVQKGG	PDZK1	396	Q5T2W1
TGLVGLQDKKVGALP	MECOM	676	Q03112
LRGPSAGGQKLLQKS	HS3ST2	56	Q9Y278
ARTKVPIFLGIQGGS	IL1F10	51	Q8WWZ1
KLKSGIGAVVLPGVS	KMT2C	911	Q8NEZ4
DTKVKRGAGNGVVPA	MDC1	271	Q14676
RTPSAGGLKAEGQLK	KIAA0825	786	Q8IV33
SGIVVNGQLVGAKKP	ITIH2	736	P19823
QVKSRSGTLGQILPG	ITPRID1	676	Q6ZRS4
RIPVKGVSRQDGKGD	GPR179	2026	Q6PRD1
PGSGKGTQSLKIAER	AK5	141	Q9Y6K8
EKPGSGEGLGKIIQR	SBF2	16	Q86WG5
KGGPVSAGTSILRKT	KRT79	511	Q5XKE5
ITPKIVGGSNAKEGA	TMPRSS15	781	P98073
AGKIQKGRELSLVGP	CPVL	51	Q9H3G5
KVTAKGPGLEAVGNI	FLNB	356	O75369
PKAIIIGVRKGGTRA	HS3ST5	91	Q8IZT8
VAEGSPQRVNGKVKG	NID1	426	P14543
GKVKGRIFVGSSQVP	NID1	436	P14543
NKTEAVPRVGGLLGK	FAM217B	166	Q9NTX9
AQGRPSQKGGLVVLK	GALNT11	496	Q8NCW6
SKVRASGPGLERGKV	FLNC	1156	Q14315
LGGRSGALKNFVIPK	NIPBL	946	Q6KC79
RNKAITSLLGGGSPK	NIPBL	2646	Q6KC79
DLGTPKTVKGVIIQG	NRP2	491	O60462
KTKTLSGGIKVNGPR	GBP3	276	Q9H0R5
LVTGGSGLVGKAIQK	GFUS	11	Q13630
IKVGIGPGSVCTTRK	GMPR2	176	Q9P2T1
KGDGKGTRQRIPLTD	PRR25	201	Q96S07
PGLRKSGVGNIFIKN	PABPC1L	91	Q4VXU2
NLVGAILGKGGKTLV	NOVA2	416	Q9UNW9
AKEQRQTPGKGLISG	NOP14	396	P78316
QTPGKGLISGKERAG	NOP14	401	P78316
TAKIQIVRGGSTAKG	OAS2	386	P29728
GNTLTPFTKVRLVGG	MSR1	341	P21757
PSNLGKFTKGTLLGR	CCSER2	146	Q9H7U1
LSTGFKIPQKGILIG	CPS1	1351	P31327
QGLRGSLTKLKGPLT	CSF2	81	P04141
TGKTGRAGDQPLKII	DPH7	151	Q9BTV6
KARGPGLEKTGVAVN	FLNA	676	P21333
IIRKPGSAKVQSGFI	CEP126	756	Q9P2H0
SLKGKLGARQSGPRT	GAS2L2	691	Q8NHY3
KVGIVRLTGASDKPG	BBOX1	146	O75936
RSPRGKNIQGGKTLS	CD4	156	P01730
VFVNPKSGGKQGERI	DGKB	441	Q9Y6T7
LKEKRVGGVQSLGGT	GOT1	96	P17174
GVRPGKNVKVTTQGL	CCR2	336	P41597
VVGARSVLSGKGALP	MAST2	1451	Q6P0Q8
KEVAKGSIGRGVLPA	GABBR2	66	O75899
VQKTTGKGTTIQGLP	EMSY	581	Q7Z589
GKGTTIQGLPGKNVV	EMSY	586	Q7Z589
PKRGVFGKTGDLQTI	EML5	186	Q05BV3
LIVTGGKERPSKEGG	EML5	1616	Q05BV3
GKRKGPGEGVLTLRA	EPS8	306	Q12929
TGAVLPSGNTLRVKK	FRY	521	Q5TBA9
GTKKDNSILEIRGPG	FLRT1	576	Q9NZU1
ERVSVGKAGTVSPGK	GPRIN1	441	Q7Z2K8
LTVSGGIDKDGKPRV	GRIP1	66	Q9Y3R0
LSRPTAAIGLKGEKG	COL15A1	756	P39059
GSEQKRKVLEATGPG	CEP131	51	Q9UPN4
ISGGKSLVLRKQHPG	FAM87A	11	P0C7U9
RIPGLGKELQTGTHK	CARD16	181	Q5EG05
PQALIVGVKKGGTRA	HS3ST6	91	Q96QI5
TRVVAKDGLKLGSGP	PTTG1	16	O95997
TGLLGFVRQVKSKSP	PTPRM	1071	P28827
NLVGAILGKGGKTLV	NOVA1	431	P51513
APRVLKTVKGGSSGR	OAS3	51	Q9Y6K5
LLNRKPQGGSGEIKT	PANK1	101	Q8TE04
GGDKGRVKVITGPNS	MSH5	581	O43196
RAVLIAGQPGTGKTA	RUVBL2	71	Q9Y230
QIDRPATGTGSKVGK	RUVBL2	146	Q9Y230
KGRARGTAPKVTGTQ	SYDE2	206	Q5VT97
GSPNKKHVGVILQRG	SLC47A2	101	Q86VL8
VKKGVNIIGVRASSP	TMEM132D	326	Q14C87
IFGKKARVVITQSPG	TMEM185B	321	Q9H7F4
GLQVKAASVPVKGSL	TCOF1	721	Q13428
TQRAKTGKDPVVGAG	TAL1	251	P17542
AVGKVIPELNGKLTG	GAPDH	216	P04406
VVKQASEGPLKGILG	GAPDH	261	P04406
GAGKPAAVVLQTKGS	GANAB	896	Q14697
SLLVGPLVNKFGRKG	SLC2A5	86	P22732
GLKPGTKVTIRASRG	POGZ	681	Q7Z3K3
TKGKRLSPQGLILQG	MEP1A	606	Q16819
ALLGRETVGKKEPTG	PPP1R32	306	Q7Z5V6
RGVSTVCGKPKVVGK	PRSS47P	66	A8MTI9
VPLSGSQIVKGKLAG	POLR1G	61	O15446
KSKPGVQEGIQVLGS	SNCAIP	586	Q9Y6H5
KLPKGISAGAVQTAG	NOP2	76	P46087
AGARKKRAAGQSGVP	PLA2G3	126	Q9NZ20
VIKAQVLAGGRGKGT	SUCLA2	96	Q9P2R7
KIKVTRGPATATLAG	TRIOBP	1666	Q9H2D6
TQKGPLKAGEQRAGS	TRIOBP	1911	Q9H2D6
KVVGAKVVTNARSPG	SAFB	431	Q15424
KPRLGQEATVGKATG	ACLY	86	P53396
FGPTGNKTLGLAIKR	CLN5	276	O75503
PTSGIIGVNKKGQVL	CLTCL1	311	P53675
KAAKVPLGGVQSVSL	C11orf16	201	Q9NQ32
GKGAAKLRVAGVVAP	RECQL	521	P46063
PKASTVVKGVASGLR	PLCXD3	251	Q63HM9
IGKPGGVSLSKIERS	TPST2	271	O60704
KIQTQKTKPRGLGGD	ZCWPW1	481	Q9H0M4
DVAGEKGIQKIPSGR	TICRR	601	Q7Z2Z1
QKPRGLEGGVLRGSK	ZSWIM9	531	Q86XI8
LKGAPSGTVRIGVAK	MPDZ	771	O75970
GSLRKGIPRTKSVGE	SHANK3	771	Q9BYB0
GVSAKNVTLGVPRLK	POLR2A	1111	P24928
GTGVALGRNQPLKKE	UBTD2	21	Q8WUN7
IIGGGVKAPRIKTKN	ATP6V0B	76	Q99437
TQGLLTAKGGVGKLV	SUGP2	231	Q8IX01
AGKTTVGRIIGQKLG	THNSL1	66	Q8IYQ7
KGRGGSVIKTQPSRG	SPRED2	281	Q7Z698
GKVVGAKVVTNARSP	SAFB2	431	Q14151
AAPAVQLVKKGNRGG	RPAP1	26	Q9BWH6
KTSGLGSPRAIKRGV	PLEKHH1	516	Q9ULM0
GLPGSGKTHVAKLIR	YLPM1	1841	P49750
SVIPGGFIKQLVRGT	MYO18B	31	Q8IUG5
EGQSIVGKGLGTPKT	MYO18B	236	Q8IUG5
PQNSKVDKGVLGRIG	TOPAZ1	1351	Q8N9V7
AISQSGRVLGKSPGK	ZNF507	826	Q8TCN5
GRVLGKSPGKTQLKS	ZNF507	831	Q8TCN5
KVLGNPGRGSIKTVA	USP37	161	Q86T82
VDQGGGGSPRKKVAL	USP24	1936	Q9UPU5
DSGGRVKGVTIVKPI	YEATS4	11	O95619
RPLVTDKGKRVGGSI	ARHGAP21	941	Q5T5U3
VREKVRGASGGALPK	USP13	96	Q92995
KIITGKPSGAISGVQ	TBK1	236	Q9UHD2
TGGLFQGKTPLRKAN	TPX2	51	Q9ULW0
QGVSGVKPTGLRKRT	MYO5A	1636	Q9Y4I1
SLQGISGLKPTGFRK	MYO5C	1521	Q9NQX4
LTTAGGTKGTVIKVP	MYO6	396	Q9UM54