Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process	A1CF YBX1 NCBP1 CAPRIN1 HNRNPU SAMD4A	6.24e-06	132	71	6	GO:0000956
GeneOntologyBiologicalProcess	mRNA catabolic process	YBX2 A1CF YBX1 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	4.18e-05	373	71	8	GO:0006402
GeneOntologyBiologicalProcess	positive regulation of collagen fibril organization	EFEMP2 TNXB	6.98e-05	4	71	2	GO:1904028
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	YBX1 CAPRIN1 HNRNPU SAMD4A	7.45e-05	65	71	4	GO:0000288
GeneOntologyBiologicalProcess	regulation of mRNA catabolic process	YBX2 A1CF YBX1 PUM1 CAPRIN1 HNRNPU SAMD4A	9.26e-05	309	71	7	GO:0061013
GeneOntologyBiologicalProcess	RNA catabolic process	YBX2 A1CF YBX1 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	1.16e-04	432	71	8	GO:0006401
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	YBX2 A1CF YBX1 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	1.38e-04	443	71	8	GO:1903311
GeneOntologyBiologicalProcess	nucleic acid catabolic process	YBX2 A1CF YBX1 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	1.90e-04	464	71	8	GO:0141188
GeneOntologyBiologicalProcess	negative regulation of mRNA catabolic process	YBX2 A1CF YBX1 HNRNPU	2.31e-04	87	71	4	GO:1902373
GeneOntologyBiologicalProcess	positive regulation of mRNA metabolic process	YBX1 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	2.68e-04	259	71	6	GO:1903313
GeneOntologyBiologicalProcess	regulation of translation	YBX2 YBX1 MTIF2 NCBP1 PUM1 CAPRIN1 HNRNPU SAMD4A	2.90e-04	494	71	8	GO:0006417
GeneOntologyCellularComponent	CRD-mediated mRNA stability complex	YBX1 HNRNPU	1.79e-04	6	73	2	GO:0070937
GeneOntologyCellularComponent	cytoplasmic ribonucleoprotein granule	YBX1 KIF3C PUM1 CAPRIN1 HNRNPU SAMD4A	3.55e-04	269	73	6	GO:0036464
GeneOntologyCellularComponent	P-body	YBX1 PUM1 CAPRIN1 SAMD4A	4.49e-04	102	73	4	GO:0000932
GeneOntologyCellularComponent	external encapsulating structure	SNED1 FBN1 DST EFEMP2 ADAMTS17 LAMA2 HAPLN3 PKHD1L1 TNXB	4.62e-04	658	73	9	GO:0030312
GeneOntologyCellularComponent	ribonucleoprotein granule	YBX1 KIF3C PUM1 CAPRIN1 HNRNPU SAMD4A	5.01e-04	287	73	6	GO:0035770
GeneOntologyCellularComponent	neuron projection cytoplasm	DST GRIA2 KIF3C HNRNPU	5.98e-04	110	73	4	GO:0120111
GeneOntologyCellularComponent	dendrite	ERBB4 YBX1 LAMA2 GRIA2 APLP2 KIF3C GRM3 CAPRIN1 HNRNPU SAMD4A	7.68e-04	858	73	10	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ERBB4 YBX1 LAMA2 GRIA2 APLP2 KIF3C GRM3 CAPRIN1 HNRNPU SAMD4A	7.82e-04	860	73	10	GO:0097447
GeneOntologyCellularComponent	basement membrane	FBN1 DST EFEMP2 LAMA2	8.81e-04	122	73	4	GO:0005604
GeneOntologyCellularComponent	microfibril	FBN1 EFEMP2	9.15e-04	13	73	2	GO:0001527
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA2 TNXB	1.58e-03	17	73	2	GO:0098637
GeneOntologyCellularComponent	extracellular matrix	SNED1 FBN1 DST EFEMP2 ADAMTS17 LAMA2 HAPLN3 TNXB	2.01e-03	656	73	8	GO:0031012
Domain	Pectin_lyase_fold/virulence	FBXO11 PKHD1L1 CEMIP2	3.16e-06	8	73	3	IPR011050
Domain	EGF-like_dom	SNED1 FBN1 CELSR2 EFEMP2 LAMA2 ADAM29 C7 TNXB	5.68e-06	249	73	8	IPR000742
Domain	EGF_1	SNED1 FBN1 CELSR2 EFEMP2 LAMA2 ADAM29 C7 TNXB	6.76e-06	255	73	8	PS00022
Domain	EGF-like_CS	SNED1 FBN1 CELSR2 EFEMP2 LAMA2 ADAM29 C7 TNXB	8.01e-06	261	73	8	IPR013032
Domain	EGF_2	SNED1 FBN1 CELSR2 EFEMP2 LAMA2 ADAM29 C7 TNXB	8.95e-06	265	73	8	PS01186
Domain	EGF_3	SNED1 FBN1 CELSR2 EFEMP2 ADAM29 C7 TNXB	3.67e-05	235	73	7	PS50026
Domain	G8	PKHD1L1 CEMIP2	9.00e-05	4	73	2	PF10162
Domain	G8_domain	PKHD1L1 CEMIP2	9.00e-05	4	73	2	IPR019316
Domain	G8	PKHD1L1 CEMIP2	9.00e-05	4	73	2	PS51484
Domain	G8	PKHD1L1 CEMIP2	9.00e-05	4	73	2	SM01225
Domain	COLD_SHOCK	YBX2 YBX1	2.24e-04	6	73	2	PS00352
Domain	PbH1	FBXO11 PKHD1L1	2.24e-04	6	73	2	SM00710
Domain	Cold-shock_CS	YBX2 YBX1	2.24e-04	6	73	2	IPR019844
Domain	PbH1	FBXO11 PKHD1L1	2.24e-04	6	73	2	IPR006626
Domain	EGF	SNED1 FBN1 CELSR2 EFEMP2 LAMA2 TNXB	3.14e-04	235	73	6	SM00181
Domain	Growth_fac_rcpt_	ERBB4 FBN1 CELSR2 EFEMP2 TNXB	3.62e-04	156	73	5	IPR009030
Domain	CSP	YBX2 YBX1	4.16e-04	8	73	2	SM00357
Domain	Cold_shock_prot	YBX2 YBX1	4.16e-04	8	73	2	IPR011129
Domain	CSD	YBX2 YBX1	4.16e-04	8	73	2	PF00313
Domain	CSP_DNA-bd	YBX2 YBX1	4.16e-04	8	73	2	IPR002059
Domain	ASX_HYDROXYL	SNED1 FBN1 CELSR2 EFEMP2	6.34e-04	100	73	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 FBN1 CELSR2 EFEMP2	7.90e-04	106	73	4	IPR000152
Domain	MBOAT_fam	MBOAT2 DGAT1	8.10e-04	11	73	2	IPR004299
Domain	MBOAT	MBOAT2 DGAT1	8.10e-04	11	73	2	PF03062
Domain	UBX	UBXN4 NSFL1C	9.70e-04	12	73	2	SM00166
Domain	UBX	UBXN4 NSFL1C	1.14e-03	13	73	2	PF00789
Domain	UBX	UBXN4 NSFL1C	1.14e-03	13	73	2	PS50033
Domain	UBX_dom	UBXN4 NSFL1C	1.14e-03	13	73	2	IPR001012
Domain	CCP	SNED1 C7 CSMD3	1.23e-03	54	73	3	SM00032
Domain	EGF_CA	SNED1 FBN1 CELSR2 EFEMP2	1.33e-03	122	73	4	SM00179
Domain	SUSHI	SNED1 C7 CSMD3	1.37e-03	56	73	3	PS50923
Domain	EGF-like_Ca-bd_dom	SNED1 FBN1 CELSR2 EFEMP2	1.41e-03	124	73	4	IPR001881
Domain	Sushi_SCR_CCP_dom	SNED1 C7 CSMD3	1.44e-03	57	73	3	IPR000436
Domain	TSP_1	ADAMTS17 C7 THSD1	1.92e-03	63	73	3	PF00090
Domain	TSP1	ADAMTS17 C7 THSD1	2.10e-03	65	73	3	SM00209
Domain	TSP1_rpt	ADAMTS17 C7 THSD1	2.10e-03	65	73	3	IPR000884
Domain	TSP1	ADAMTS17 C7 THSD1	2.10e-03	65	73	3	PS50092
Domain	-	SPINT2 APLP2	2.21e-03	18	73	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	SPINT2 APLP2	2.21e-03	18	73	2	IPR020901
Domain	KU	SPINT2 APLP2	2.21e-03	18	73	2	SM00131
Domain	BPTI_KUNITZ_2	SPINT2 APLP2	2.47e-03	19	73	2	PS50279
Domain	Kunitz_BPTI	SPINT2 APLP2	2.47e-03	19	73	2	PF00014
Domain	BPTI_KUNITZ_1	SPINT2 APLP2	2.47e-03	19	73	2	PS00280
Domain	Kunitz_BPTI	SPINT2 APLP2	3.61e-03	23	73	2	IPR002223
Pubmed	UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.	UBXN4 NSFL1C WDR26 NPLOC4 KLHL22	2.09e-07	62	73	5	18775313
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	ZKSCAN1 YBX1 NCBP1 NOL9 API5 FLG2 VIRMA CAPRIN1 HNRNPU VDAC2	5.47e-07	605	73	10	28977666
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	IVNS1ABP FASN YBX1 TAB1 WDR26 HNRNPU VDAC2	1.16e-06	256	73	7	32698014
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	A1CF DST YBX1 API5 PUM1 CAPRIN1 CNN2	1.22e-06	258	73	7	37794589
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	IVNS1ABP DOCK4 FASN YBX1 TAB1 WDR26 HNRNPU VDAC2	1.45e-06	383	73	8	29331416
Pubmed	Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.	IVNS1ABP YBX1 NCBP1 HNRNPU	1.54e-06	40	73	4	23825951
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	IVNS1ABP DOCK4 CRTC3 ERBB4 DST TAB1 PUM1 WDR26 VIRMA NSD3 SAMD4A	1.77e-06	861	73	11	36931259
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	DOCK4 FASN YBX1 TAB1 TEX15 WDR26	2.56e-06	184	73	6	23402259
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK4 ERBB4 UBXN4 NSFL1C CELSR2 YBX1 GRIA2 TAB1 ALDH6A1 WDR26 CAPRIN1 HNRNPU	4.19e-06	1139	73	12	36417873
Pubmed	Internalization of AMPA-type Glutamate Receptor in the MIN6 Pancreatic β-cell Line.	GRIA2 GRM3	4.35e-06	2	73	2	32581155
Pubmed	A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix.	FBN1 ADAMTS17	4.35e-06	2	73	2	31726086
Pubmed	Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2.	YBX2 YBX1	4.35e-06	2	73	2	9780336
Pubmed	TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes.	FASN TSHR	4.35e-06	2	73	2	25655684
Pubmed	Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches.	IVNS1ABP DOCK4 UBXN4 NSFL1C YBX1 NPLOC4	4.39e-06	202	73	6	29540532
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	FASN A1CF YBX1 PEG3 FBXO11 NCBP1 NOL9 FLG2 VIRMA CAPRIN1 CNN2 NPLOC4 VDAC2	5.00e-06	1371	73	13	36244648
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	IVNS1ABP FASN YBX1 B3GALNT2 FLG2 PUM1 CAPRIN1 CEMIP2 VDAC2	5.51e-06	613	73	9	22268729
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	ZKSCAN1 YBX1 FBXO11 NCBP1 WDR26 CAPRIN1 HNRNPU SAMD4A	5.76e-06	462	73	8	31138677
Pubmed	Cold shock domain family members YB-1 and MSY4 share essential functions during murine embryogenesis.	YBX2 YBX1	1.30e-05	3	73	2	16954378
Pubmed	The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment.	FASN DGAT1	1.30e-05	3	73	2	16894240
Pubmed	Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death.	ERBB4 A1CF	1.30e-05	3	73	2	23929941
Pubmed	CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma progression and lipid metabolism reprogramming by stabilizing PTBP1 to facilitate FASN mRNA cytoplasmic export.	FASN MBOAT2	1.30e-05	3	73	2	36635270
Pubmed	The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function.	A1CF DGAT1	1.30e-05	3	73	2	29563512
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	DST NSFL1C YBX1 TAB1 CNN2 NPLOC4	1.88e-05	261	73	6	33277362
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	IVNS1ABP FASN YBX1 TAB1 API5 WDR26 CAPRIN1 HNRNPU	2.05e-05	551	73	8	34728620
Pubmed	Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.	FASN FBN1 YBX1 CAPRIN1 HNRNPU VDAC2	2.33e-05	271	73	6	26816005
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	FASN TAB1 FLG2 WDR26 CAPRIN1 HNRNPU	2.38e-05	272	73	6	31010829
Pubmed	Elastogenic protein expression of a highly elastic murine spinal ligament: the ligamentum flavum.	FBN1 EFEMP2	2.60e-05	4	73	2	22685574
Pubmed	Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.	SPINT2 APLP2	2.60e-05	4	73	2	25301953
Pubmed	YB-1 binds to GluR2 mRNA and CaM1 mRNA in the brain and regulates their translational levels in an activity-dependent manner.	YBX1 GRIA2	2.60e-05	4	73	2	20614234
Pubmed	Weill-Marchesani Syndrome	FBN1 ADAMTS17	2.60e-05	4	73	2	20301293
Pubmed	Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice.	GRIA2 GRM3	2.60e-05	4	73	2	15619115
Pubmed	ATPase activity of p97/valosin-containing protein is regulated by oxidative modification of the evolutionally conserved cysteine 522 residue in Walker A motif.	NSFL1C NPLOC4	2.60e-05	4	73	2	16234241
Pubmed	Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus.	GRIA2 GRM3	2.60e-05	4	73	2	16733060
Pubmed	Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.	GRIA2 GRM3	2.60e-05	4	73	2	19477188
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	IVNS1ABP FASN DST NSFL1C YBX1 TAB1 NOL9 API5 WDR26 CAPRIN1 HNRNPU	2.66e-05	1149	73	11	35446349
Pubmed	Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.	YBX1 CAPRIN1 HNRNPU	2.80e-05	28	73	3	38492217
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DST CELSR2 ZKSCAN1 GRIA2 NOL9 GRM3 WDR26 VIRMA CAPRIN1 HNRNPU	3.24e-05	963	73	10	28671696
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	UBXN4 SPINT2 APLP2 MBOAT2 CEMIP2	3.56e-05	176	73	5	28692057
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	UBXN4 DST YBX1 RPGR FLG2 PCDH10 PKHD1L1 PCDH9 CEMIP2	3.59e-05	777	73	9	35844135
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IVNS1ABP FASN YBX1 NCBP1 APLP2 KIF3C NOL9 API5 PUM1 CAPRIN1 HNRNPU VDAC2	3.88e-05	1425	73	12	30948266
Pubmed	Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.	FASN WDR26 CAPRIN1	4.21e-05	32	73	3	19542561
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	FASN DST YBX1 DAB2 TRAPPC10 NCBP1 WDR26 CAPRIN1 NPLOC4 HNRNPU VDAC2 SAMD4A	4.30e-05	1440	73	12	30833792
Pubmed	Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.	NSFL1C NPLOC4	4.33e-05	5	73	2	12411482
Pubmed	Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury.	ERBB4 A1CF	4.33e-05	5	73	2	19632177
Pubmed	Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response.	NSFL1C NPLOC4	4.33e-05	5	73	2	27226613
Pubmed	Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.	FBN1 EFEMP2	4.33e-05	5	73	2	17255108
Pubmed	A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.	NSFL1C NPLOC4	4.33e-05	5	73	2	10811609
Pubmed	Differential regulation of elastic fiber formation by fibulin-4 and -5.	FBN1 EFEMP2	4.33e-05	5	73	2	19570982
Pubmed	PEG3 controls lipogenesis through ACLY.	FASN PEG3	4.33e-05	5	73	2	34048454
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	IVNS1ABP YBX1 FBXO11 CAPRIN1 HNRNPU	5.00e-05	189	73	5	29449217
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	DST NPLOC4 HNRNPU	5.53e-05	35	73	3	22337587
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	YBX2 FASN A1CF YBX1 CAPRIN1 HNRNPU VDAC2	5.87e-05	469	73	7	37314180
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FASN DST YBX1 NCBP1 NOL9 FLG2 VIRMA CAPRIN1 HNRNPU NSD3 VDAC2	6.00e-05	1257	73	11	36526897
Pubmed	Molecular composition of IMP1 ribonucleoprotein granules.	YBX1 NCBP1 HNRNPU	6.03e-05	36	73	3	17289661
Pubmed	Proteomic and genomic analysis of PITX2 interacting and regulating networks.	YBX1 HNRNPU	6.48e-05	6	73	2	19174163
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBN1 EFEMP2	6.48e-05	6	73	2	19349279
Pubmed	Single-Cell Transcriptomics Reveals Regulators of Neuronal Migration and Maturation During Brain Development.	CELSR2 PCDH9	6.48e-05	6	73	2	29551912
Pubmed	VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.	NSFL1C NPLOC4	6.48e-05	6	73	2	27913212
Pubmed	Identification of proteins that interact with BRCA1 by Far-Western library screening.	PEG3 APLP2	6.48e-05	6	73	2	11746496
Pubmed	Hierarchical binding of cofactors to the AAA ATPase p97.	NSFL1C NPLOC4	6.48e-05	6	73	2	21645854
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	FASN DST YBX1 FLG2 NPLOC4 HNRNPU VDAC2	6.52e-05	477	73	7	31300519
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	YBX2 CRTC3 FASN YBX1 PUM1 CAPRIN1 HNRNPU VDAC2	6.95e-05	655	73	8	35819319
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FBN1 DST CIAO3 MTIF2 EFEMP2 PEG3 FBXO11 NCBP1 WDR26 CAPRIN1 DSCAML1	7.31e-05	1285	73	11	35914814
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DST YBX1 FBXO11 NCBP1 APLP2 FLG2 TNXB HNRNPU NSD3 VDAC2	8.57e-05	1082	73	10	38697112
Pubmed	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	YBX2 YBX1 CAPRIN1 CNN2 HNRNPU	8.61e-05	212	73	5	23463506
Pubmed	DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage.	NSFL1C NPLOC4	9.06e-05	7	73	2	23042607
Pubmed	Staufen 1 is expressed by neural precursor cells in the developing murine cortex but is dispensable for NPC self-renewal and neuronal differentiation in vitro.	PUM1 SAMD4A	9.06e-05	7	73	2	34678304
Pubmed	Imbalances in p97 co-factor interactions in human proteinopathy.	NSFL1C NPLOC4	9.06e-05	7	73	2	20414249
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	NCBP1 PUM1 VIRMA CAPRIN1	1.00e-04	114	73	4	31553912
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	FASN YBX1 PEG3 NCBP1 API5 WDR26 CAPRIN1 CNN2 NPLOC4 HNRNPU VDAC2	1.02e-04	1335	73	11	29229926
Pubmed	Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate.	NSFL1C YBX1 CAPRIN1 HNRNPU	1.07e-04	116	73	4	27576135
Pubmed	FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.	NSFL1C YBX1 NPLOC4 HNRNPU VDAC2	1.11e-04	224	73	5	28443643
Pubmed	Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.	FBN1 ADAMTS17	1.21e-04	8	73	2	31201465
Pubmed	Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect.	UBXN4 NSFL1C	1.21e-04	8	73	2	25078495
Pubmed	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.	YBX1 HNRNPU	1.21e-04	8	73	2	19029303
Pubmed	Interaction of two multifunctional proteins. Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein.	YBX1 HNRNPU	1.21e-04	8	73	2	10809782
Pubmed	The N-terminal domain of the Schaaf-Yang syndrome protein MAGEL2 likely has a role in RNA metabolism.	NSFL1C YBX1 HNRNPU	1.26e-04	46	73	3	34265304
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	UBXN4 SPINT2 YBX1 CAPRIN1 NPLOC4 VDAC2	1.40e-04	375	73	6	32788342
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	IVNS1ABP UBXN4 NSFL1C KIF3C TAB1 WDR26	1.46e-04	378	73	6	34315543
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	YBX1 NCBP1 VIRMA CNN2 HNRNPU	1.51e-04	239	73	5	26641092
Pubmed	Distribution of protocadherin 9 protein in the developing mouse nervous system.	PCDH10 PCDH9	1.55e-04	9	73	2	22982106
Pubmed	Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.	CAPRIN1 NPLOC4	1.55e-04	9	73	2	34739333
Pubmed	The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins.	YBX2 YBX1	1.55e-04	9	73	2	8871564
Pubmed	Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.	DAB2 APLP2	1.55e-04	9	73	2	11247302
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	IVNS1ABP TAB1 API5 FLG2 HNRNPU	1.69e-04	245	73	5	35652658
Pubmed	A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.	YBX1 CAPRIN1 VDAC2	1.72e-04	51	73	3	26839216
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	IVNS1ABP FASN YBX1 TAB1 FLG2 CAPRIN1 HNRNPU	1.72e-04	558	73	7	27591049
Pubmed	Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.	YBX1 CAPRIN1 HNRNPU	1.82e-04	52	73	3	26265008
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	FASN UBXN4 DST DAB2 CNN2 NPLOC4 CEMIP2	1.92e-04	568	73	7	37774976
Pubmed	E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.	FASN DST FLG2 HNRNPU	1.92e-04	135	73	4	29859926
Pubmed	Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.	FBXO11 NSD3	1.93e-04	10	73	2	22421440
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	YBX2 FASN UBXN4 DST SUGCT YBX1 TTC16 CIAO3 GRIA2 NCBP1 HNRNPU	2.01e-04	1442	73	11	35575683
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FASN NSFL1C ZKSCAN1 YBX1 FBXO11 NCBP1 VIRMA CEMIP2 HNRNPU VDAC2	2.03e-04	1203	73	10	29180619
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SNED1 FASN UBXN4 FBN1 CELSR2 YBX1 MTIF2 EFEMP2 KIF3C HNRNPU VDAC2	2.12e-04	1451	73	11	30550785
Pubmed	The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.	YBX1 PUM1 HNRNPU	2.15e-04	55	73	3	31640799
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	IVNS1ABP CRTC3 FASN NSFL1C YBX1 NCBP1 API5 WDR26 CNN2 NPLOC4 HNRNPU	2.17e-04	1455	73	11	22863883
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK4 PEG3 PUM1 CSMD3 PCDH10 VIRMA	2.18e-04	407	73	6	12693553
Pubmed	A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.	ERBB4 FBN1	2.36e-04	11	73	2	17903305
Pubmed	Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.	A1CF PUM1	2.36e-04	11	73	2	28978771
Pubmed	Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.	FASN DGAT1	2.36e-04	11	73	2	14668353
Interaction	CSDE1 interactions	FASN YBX1 NCBP1 PUM1 VIRMA CAPRIN1 HNRNPU SAMD4A	8.57e-06	284	73	8	int:CSDE1
Interaction	ZFP36L2 interactions	IVNS1ABP FASN YBX1 FBXO11 PUM1 CAPRIN1 HNRNPU	1.13e-05	211	73	7	int:ZFP36L2
Cytoband	5p13	DAB2 C7	3.34e-04	17	73	2	5p13
GeneFamily	Y box binding proteins	YBX2 YBX1	1.90e-05	3	46	2	106
GeneFamily	EF-hand domain containing\|S100 fused type protein family	RPTN FLG2	1.32e-04	7	46	2	1350
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SNED1 C7 CSMD3	4.10e-04	57	46	3	1179
GeneFamily	Non-clustered protocadherins	PCDH10 PCDH9	4.11e-04	12	46	2	21
GeneFamily	UBX domain containing	UBXN4 NSFL1C	4.85e-04	13	46	2	364
GeneFamily	Kelch like\|BTB domain containing	IVNS1ABP KLHL22	5.11e-03	42	46	2	617
GeneFamily	Fibronectin type III domain containing	SNED1 TNXB DSCAML1	7.81e-03	160	46	3	555
GeneFamily	EF-hand domain containing	DST RPTN FLG2	1.82e-02	219	46	3	863
Coexpression	GSE3982_NEUTROPHIL_VS_TH1_UP	IVNS1ABP DOCK4 NSFL1C GRIA2 APLP2 WDR26	1.87e-05	197	73	6	M5532
Coexpression	GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP	IVNS1ABP ERBB4 RPTN KIF3C TSHR HNRNPU	2.04e-05	200	73	6	M5122
Coexpression	GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_UP	IVNS1ABP SPINT2 RPTN TSHR GRM3 PCDH9	2.04e-05	200	73	6	M7903
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN	SNED1 FASN NXPE4 API5 PUM1 NPLOC4	2.04e-05	200	73	6	M6583
Coexpression	GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN	FASN YBX1 RPTN KIF3C ALDH6A1 DGAT1	2.04e-05	200	73	6	M3929
Coexpression	NABA_MATRISOME_POORLY_METASTATIC_BREAST_CANCER	LAMA2 FLG2 TNXB	4.56e-05	25	73	3	M47986
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN	FBN1 ATP8A1 ZKSCAN1 DAB2 MBOAT2 PCDH9 CNN2 SAMD4A	7.95e-05	504	73	8	M2157
Coexpression	ONDER_CDH1_TARGETS_2_UP	DOCK4 SNED1 FBN1 DAB2 ALDH6A1 PCDH9	8.24e-05	257	73	6	M13867
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DOCK4 FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	8.18e-10	187	73	8	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK4 SNED1 FBN1 DST ABCA6 LAMA2 C7 CSMD3	1.09e-09	194	73	8	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SNED1 FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	1.14e-09	195	73	8	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SNED1 FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	1.39e-09	200	73	8	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SNED1 FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	1.39e-09	200	73	8	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SNED1 FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	1.39e-09	200	73	8	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB PCDH9	2.30e-08	185	73	7	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP2 ADAMTS17 LAMA2 C7 GRM3 TNXB	2.30e-08	185	73	7	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP2 ADAMTS17 LAMA2 C7 GRM3 TNXB	2.30e-08	185	73	7	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP2 ADAMTS17 LAMA2 C7 GRM3 TNXB	2.38e-08	186	73	7	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	FBN1 DST ABCA6 SUGCT LAMA2 C7 TNXB	2.47e-08	187	73	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB PCDH9	2.57e-08	188	73	7	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	2.86e-08	191	73	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 ADAMTS17 LAMA2 C7 TNXB	2.97e-08	192	73	7	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	2.97e-08	192	73	7	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 FBN1 DST ABCA6 ADAMTS17 LAMA2 TNXB	3.07e-08	193	73	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 FBN1 DST ABCA6 ADAMTS17 LAMA2 TNXB	3.18e-08	194	73	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SNED1 FBN1 DST ABCA6 LAMA2 C7 TNXB	3.30e-08	195	73	7	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	3.42e-08	196	73	7	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	SNED1 FBN1 DST ABCA6 SUGCT LAMA2 C7	3.54e-08	197	73	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	SNED1 FBN1 DST ABCA6 SUGCT LAMA2 C7	3.54e-08	197	73	7	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	tumor_Lung-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	3.66e-08	198	73	7	2d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SNED1 FBN1 DST ABCA6 LAMA2 C7 SAMD4A	3.66e-08	198	73	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SNED1 FBN1 EFEMP2 LAMA2 C7 FLG2 CNN2	3.79e-08	199	73	7	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	SNED1 FBN1 DST ABCA6 LAMA2 C7 TNXB	3.79e-08	199	73	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FBN1 DST ABCA6 EFEMP2 ADAMTS17 C7 TNXB	3.79e-08	199	73	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DOCK4 FBN1 DST ABCA6 EFEMP2 C7 TNXB	3.79e-08	199	73	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SNED1 FBN1 EFEMP2 LAMA2 C7 FLG2 CNN2	3.79e-08	199	73	7	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DOCK4 FBN1 DST ABCA6 EFEMP2 C7 TNXB	3.92e-08	200	73	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SNED1 FBN1 ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB SAMD4A	3.92e-08	200	73	7	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	343B-Fibroblasts\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	376c1a77031e090be96948b47c78ac0d393f5775
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK4 FBN1 ABCA6 EFEMP2 TEX15 C7 TNXB	3.92e-08	200	73	7	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 DST ABCA6 LAMA2 C7 TNXB SAMD4A	3.92e-08	200	73	7	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK4 FBN1 DST ABCA6 LAMA2 C7 TNXB	3.92e-08	200	73	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SNED1 FBN1 ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB PCDH9	3.92e-08	200	73	7	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	FBN1 DST ABCA6 EFEMP2 C7 TNXB CEMIP2	3.92e-08	200	73	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 ABCA6 EFEMP2 DAB2 LAMA2 C7 TNXB	3.92e-08	200	73	7	74ad0ae592252060ee294d7483327d765a6ba1dd
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK4 FBN1 ABCA6 EFEMP2 TEX15 C7 TNXB	3.92e-08	200	73	7	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Fibroblast\|World / shred by cell class for parenchyma	FBN1 DST ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 DST ABCA6 ADAMTS17 LAMA2 C7 TNXB	3.92e-08	200	73	7	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 ABCA6 EFEMP2 DAB2 LAMA2 C7 TNXB	3.92e-08	200	73	7	7ba292c30d915e66ebc8026fa76492cedf64700e
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SNED1 FBN1 ABCA6 EFEMP2 LAMA2 C7 TNXB	3.92e-08	200	73	7	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK4 FBN1 DST ABCA6 TEX15 C7 TNXB	3.92e-08	200	73	7	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	367C-Fibroblasts-Fibroblast-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 ABCA6 EFEMP2 LAMA2 ADAM29 TNXB	2.05e-07	154	73	6	dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell	367C-Fibroblasts-Fibroblast-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 ABCA6 EFEMP2 LAMA2 ADAM29 TNXB	2.05e-07	154	73	6	4bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	FBN1 ABCA6 LAMA2 GRIA2 C7 TNXB	2.48e-07	159	73	6	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 TEX15 C7 TNXB	3.43e-07	168	73	6	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 FASN FBN1 LAMA2 C7 PCDH10	3.81e-07	171	73	6	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 TEX15 C7 TNXB	3.81e-07	171	73	6	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 FASN FBN1 LAMA2 C7 PCDH10	3.81e-07	171	73	6	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 TEX15 C7 TNXB	4.36e-07	175	73	6	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	4.98e-07	179	73	6	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	6.03e-07	185	73	6	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	6.03e-07	185	73	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 DST ABCA6 LAMA2 C7 TNXB	6.23e-07	186	73	6	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	6.84e-07	189	73	6	d531399749409d614adca13d181830c6e3287508
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK4 DST ABCA6 LAMA2 C7 CSMD3	6.84e-07	189	73	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.05e-07	190	73	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	FBN1 DST ABCA6 LAMA2 C7 TNXB	7.05e-07	190	73	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DOCK4 FBN1 ABCA6 PEG3 ADAMTS17 CNN2	7.27e-07	191	73	6	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.27e-07	191	73	6	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 ABCA6 EFEMP2 LAMA2 C7 TNXB	7.27e-07	191	73	6	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 ADAMTS17 LAMA2 C7	7.27e-07	191	73	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 C7 PCDH10 TNXB	7.50e-07	192	73	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.50e-07	192	73	6	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 ABCA6 EFEMP2 LAMA2 TNXB PCDH9	7.50e-07	192	73	6	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.50e-07	192	73	6	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 C7 PCDH10 TNXB	7.50e-07	192	73	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	SNED1 FBN1 DST ABCA6 SUGCT LAMA2	7.73e-07	193	73	6	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.73e-07	193	73	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	SNED1 FBN1 DST ABCA6 LAMA2 C7	7.73e-07	193	73	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.73e-07	193	73	6	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.96e-07	194	73	6	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	FBN1 DST ABCA6 SUGCT LAMA2 C7	7.96e-07	194	73	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.96e-07	194	73	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.96e-07	194	73	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	(5)_Fibroblast-C_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FBN1 DST ABCA6 EFEMP2 LAMA2 C7	7.96e-07	194	73	6	29a72e565c19407bbd198cfbc2a78106fe830d05
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	7.96e-07	194	73	6	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 FBN1 PEG3 ADAMTS17 C7 CNN2	8.21e-07	195	73	6	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 FBN1 PEG3 ADAMTS17 C7 CNN2	8.21e-07	195	73	6	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 DST ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	FBN1 DST ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 DST ABCA6 LAMA2 C7 TNXB	8.21e-07	195	73	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 ABCA6 EFEMP2 LAMA2 C7 TNXB	8.21e-07	195	73	6	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 FBN1 PEG3 ADAMTS17 C7 CNN2	8.21e-07	195	73	6	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 FBN1 PEG3 ADAMTS17 C7 CNN2	8.21e-07	195	73	6	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABCA6 LAMA2 C7 TNXB SAMD4A	8.45e-07	196	73	6	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 DST ABCA6 LAMA2 C7 TNXB	8.45e-07	196	73	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBN1 DST ABCA6 LAMA2 C7 TNXB	8.45e-07	196	73	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FASN FBN1 ABCA6 LAMA2 C7 TNXB	8.45e-07	196	73	6	988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SNED1 FBN1 DST ABCA6 C7 TNXB	8.71e-07	197	73	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SNED1 FBN1 DST ABCA6 LAMA2 C7	8.71e-07	197	73	6	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 ABCA6 PEG3 GRIA2 C7 TNXB	8.71e-07	197	73	6	6b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SNED1 FBN1 ABCA6 LAMA2 C7 TNXB	8.71e-07	197	73	6	c747c496ac090309b7f8a3e9d840928f12c83f2f
Drug	Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; PC3; HT_HG-U133A	SUGCT EFEMP2 CAPRIN1 PCDH9 ENTPD4 NSD3 KLHL22	3.28e-06	197	73	7	4233_DN
Drug	Cefotetan [69712-56-7]; Up 200; 7uM; PC3; HT_HG-U133A	A1CF PGLYRP4 ATP8A1 EFEMP2 GRM3 SAMD4A KLHL22	3.39e-06	198	73	7	3997_UP
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A	ZKSCAN1 PEG3 LAMA2 THSD1 HNRNPU NSD3 KLHL22	3.39e-06	198	73	7	7313_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	DOCK4 ATP8A1 DAB2 TEX15 ALDH6A1 PCDH9	3.54e-05	192	73	6	2450_UP
Drug	Acetaminophen [103-90-2]; Up 200; 26.4uM; HL60; HT_HG-U133A	SNED1 NXPE4 TSHR ALDH6A1 SAMD4A KLHL22	3.97e-05	196	73	6	3025_UP
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A	TRAPPC10 NCBP1 ALDH6A1 PCDH9 ENTPD4 SAMD4A	3.97e-05	196	73	6	3473_UP
Drug	Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A	A1CF FBN1 PGLYRP4 TEX15 ALDH6A1 SAMD4A	4.09e-05	197	73	6	5823_UP
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A	DOCK4 NCBP1 TAB1 HNRNPU NSD3 KLHL22	4.09e-05	197	73	6	4732_DN
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	IVNS1ABP ATP8A1 NCBP1 KIF3C NSD3 SAMD4A	4.09e-05	197	73	6	4277_DN
Drug	Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; PC3; HT_HG-U133A	EFEMP2 TRAPPC10 THSD1 ALDH6A1 CEMIP2 NSD3	4.21e-05	198	73	6	5837_DN
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A	KIF3C TSHR ALDH6A1 PCDH9 SAMD4A KLHL22	4.45e-05	200	73	6	3056_UP
Drug	3-isoxazolol	GRIA2 GRM3	6.06e-05	4	73	2	CID009964065
Drug	sunifiram	GRIA2 GRM3	6.06e-05	4	73	2	CID004223812
Drug	4-(chloromethyl)-3-methoxy-5-methylisoxazole	GRIA2 GRM3	6.06e-05	4	73	2	CID011105661
Drug	4-CO	FBN1 CIAO3	6.06e-05	4	73	2	CID000446968
Drug	AC1L1YEG	GRIA2 GRM3	1.01e-04	5	73	2	CID000063114
Drug	Chicago acid	GRIA2 GRM3	1.01e-04	5	73	2	CID000065740
Drug	CHEBI:570577	GRIA2 GRM3	1.01e-04	5	73	2	CID011334126
Drug	1-BCP	GRIA2 GRM3	1.01e-04	5	73	2	CID000001370
Drug	irampanel	GRIA2 GRM3	1.01e-04	5	73	2	CID003038472
Drug	beta-N-oxalylaminoalanine	GRIA2 GRM3	1.01e-04	5	73	2	CID000107978
Drug	LY395153	GRIA2 GRM3	1.01e-04	5	73	2	CID000656707
Drug	5-h PCA	GRIA2 GRM3	1.01e-04	5	73	2	CID000129091
Disease	refractive error, age at onset, Myopia	FBN1 LAMA2 API5 GRM3 DSCAML1 NPLOC4	8.57e-06	193	73	6	EFO_0004847, HP_0000545, MONDO_0004892
Disease	aortic aneurysm (is_implicated_in)	FBN1 EFEMP2	1.81e-05	3	73	2	DOID:3627 (is_implicated_in)
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	FBN1 ADAMTS17	1.81e-05	3	73	2	DOID:0050475 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	FBN1 ADAMTS17	3.61e-05	4	73	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 ADAMTS17	3.61e-05	4	73	2	DOID:0050475 (is_implicated_in)
Disease	visual epilepsy (implicated_via_orthology)	ERBB4 C7 VDAC2	8.23e-05	34	73	3	DOID:11832 (implicated_via_orthology)
Disease	interleukin 4 measurement	SUGCT ADAM29 GRM3	9.78e-05	36	73	3	EFO_0008184
Disease	carbonic anhydrase-related protein 10 measurement	CELSR2 C7	1.67e-04	8	73	2	EFO_0020233
Disease	mitral valve prolapse (is_implicated_in)	FBN1 TSHR	2.15e-04	9	73	2	DOID:988 (is_implicated_in)
Disease	Abnormality of refraction	FBN1 ZKSCAN1 LAMA2 API5 GRM3 PCDH9 DSCAML1 NPLOC4	2.56e-04	673	73	8	HP_0000539
Disease	gestational age	ERBB4 A1CF SUGCT GRM3	3.88e-04	138	73	4	EFO_0005112
Disease	cardiomyopathy (is_implicated_in)	TSHR DGAT1	1.00e-03	19	73	2	DOID:0050700 (is_implicated_in)
Disease	pain	CELSR2 SUGCT LAMA2 PCDH9	1.44e-03	196	73	4	EFO_0003843
Disease	retinal vasculature measurement	ERBB4 UBXN4 ZKSCAN1 LAMA2 DSCAML1 NPLOC4	1.77e-03	517	73	6	EFO_0010554
Disease	gastroesophageal reflux disease	ERBB4 ADAMTS17 PCDH9	2.03e-03	101	73	3	EFO_0003948
Disease	ganglion cell inner plexiform layer thickness measurement	ALDH6A1 NPLOC4	2.19e-03	28	73	2	EFO_0600005

Protein segments in the cluster

Peptide	Gene	Start	Entry
GYIVVGAGNNQQFAT	SUGCT	286	Q9HAC7
GGFQGILQINDFAYE	ADAM29	121	Q9UKF5
GNQFVYRDGGFAAEQ	ERBB4	1061	Q15303
PIYGRTSGNGFNFND	CSMD3	2881	Q7Z407
FNGNNRGYAFVTFSN	A1CF	91	Q9NQ94
DGMGRYNVFNFQNVG	GRM3	461	Q14832
FENRNGTDGLSYNGA	ABCA6	936	Q8N139
NLGNFNYEQRGAFRG	API5	491	Q9BZZ5
GNARGQFYLDAQTGA	CELSR2	441	Q9HCU4
AWFVGRFFQGNYGNA	DGAT1	441	O75907
QRDGYQQNFKRGSGQ	CAPRIN1	666	Q14444
NLNYGGASNFGLNFL	ATP8A1	331	Q9Y2Q0
QNEEYGGARYLGNNQ	ADAMTS17	311	Q8TE56
VRFIYGGCGGNRNNF	APLP2	336	Q06481
DYFGQQFDQISNRTG	DAB2	341	P98082
FRGDTNFYGKQGIQF	ALDH6A1	491	Q02252
YGQVQVFGFTISQGQ	NOL9	146	Q5SY16
HRFGGQGNQFSYIQS	FLG2	301	Q5D862
QSPNGRYQFNFHEGQ	HAPLN3	171	Q96S86
GLLNARNYNFGGEFV	NCBP1	91	Q09161
DAINNAAGFGFRGYD	MBOAT2	296	Q6ZWT7
TFDGVIYGFNVNAGN	MTIF2	566	P46199
NTIYAVGGFDGNEFL	IVNS1ABP	606	Q9Y6Y0
GDNKYRFFLGNQFGD	DST	7301	Q03001
LQGFNGTVFAYGQTG	KIF3C	86	O14782
QFGGANVSGFQIVDY	GRIA2	251	P42262
QFNDRKQYGSNEGHF	PCDH9	1191	Q9HC56
QGYNNISLGFAFFGT	PGLYRP4	141	Q96LB8
EFGFQNNGFSVYINR	NPLOC4	36	Q8TAT6
NYNQNFRGRGNNRGY	HNRNPU	781	Q00839
ANAQRGTYFDGTGFA	LAMA2	2936	P24043
YFSLDVQTQGDGNRF	PCDH10	166	Q9P2E7
GQRFYAGGSERSGQQ	NSFL1C	91	Q9UNZ2
IQQRVYEGNAFRGGF	PEG3	361	Q9GZU2
YEGNAFRGGFRFNST	PEG3	366	Q9GZU2
VDYFFQRQHGEQLGG	PUM1	81	Q14671
VYLIGGDNNVQGFRA	KLHL22	351	Q53GT1
AAVNGGVSRYQEAFF	DOCK4	1511	Q8N1I0
NSIFNGNQGGVYIFG	FBXO11	541	Q86XK2
QYGVVVQAFNRAGTG	DSCAML1	1061	Q8TD84
GFQYEQFSGGCQDIN	FBN1	2636	P35555
RQFDGSAFGANYSSQ	CRTC3	116	Q6UUV7
GVFYDANDVGFQRNI	B3GALNT2	161	Q8NCR0
GNGYNELTGQFRNRV	C7	141	P10643
FVGESRNYGFQGGQN	CEMIP2	831	Q9UHN6
GAYNAFQIRAGNSQG	EFEMP2	371	O95967
RGNAGQSNYGFANSA	FASN	2026	P49327
NAVYTFGLGQFGQLG	RPGR	261	Q92834
GVFNGYDGNRVTNFV	TAB1	66	Q15750
NQGYDRVIFTGQFVN	NXPE4	196	Q6UWF7
YVATFLGFGGNAARQ	ENTPD4	321	Q9Y227
IAAQAGFNAGDGQRY	SNED1	211	Q8TER0
DGSYFQINQDGGTRR	CIAO3	46	Q9H6Q4
FKCNGNGNEFYLGNS	C12orf56	241	Q8IXR9
NQSGQVFGLGRQIYD	CNN2	256	Q99439
FNVRNGYGFINRNDT	YBX2	101	Q9Y2T7
FNVRNGYGFINRNDT	YBX1	66	P67809
FDVERNSCNNFIYGG	SPINT2	151	O43291
FQYFDGANGTLRNVS	THSD1	46	Q9NS62
QFDHFLVQYRNGDGQ	TNXB	3086	P22105
TRNNFAVGYRTGDFQ	VDAC2	176	P45880
IRGEGFSQANQFNYG	PKHD1L1	51	Q86WI1
GNNTVRFNPNFYRNG	UBE2Z	171	Q9H832
QYPNGSANGFGAVRN	NSD3	91	Q9BZ95
GLYINRGDCFFQLGN	TTC16	366	Q8NEE8
RQENYGSAFPQGGEN	ZKSCAN1	256	P17029
FVTGGQRGQFYQCDL	WDR26	461	Q9H7D7
GFQQQSNFYPGFQGR	TEX15	1736	Q9BXT5
ALFSQYVVNFGAGDG	TRAPPC10	251	P48553
QEGYQNQGQGFQSRD	RPTN	626	Q6XPR3
RQFAAQTVGNTYGNF	UBXN4	346	Q92575
NYNESRGGQSNFNRG	VIRMA	1736	Q69YN4
GYRQQRNRGFGQSNS	SAMD4A	566	Q9UPU9
NNGFTSVQGYAFNGT	TSHR	186	P16473